Japanese Journal of Oral Biology最新文献_第10页

A Clinical and Histopathological Study Comparing Dental Fluorosis (Mottled Tooth) with Caries and Normal Enamel 氟斑牙伴龋和正常牙釉质的临床和组织病理学比较研究

Japanese Journal of Oral Biology Pub Date : 2001-02-20 DOI: 10.2330/JORALBIOSCI1965.43.72

Ritsuko Sato, F. Katagiri, K. Ishii, M. Katagiri

{"title":"A Clinical and Histopathological Study Comparing Dental Fluorosis (Mottled Tooth) with Caries and Normal Enamel","authors":"Ritsuko Sato, F. Katagiri, K. Ishii, M. Katagiri","doi":"10.2330/JORALBIOSCI1965.43.72","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.72","url":null,"abstract":"エナメル質の斑状白濁は, 歯のフッ素症 (斑状歯) と初期齲蝕に共通な臨床的特徴であるが, 前者は酸に抵抗性を示す。本研究は斑状歯について, 齲蝕歯と埋伏歯を対照歯とし, 0.1N塩酸による脱灰処理前後のエナメル質の構造と質を肉眼像, SEM像やCMR像によって比較し, 酸に対する抵抗性の違いを検索することを目的とした。SEM像によると, 対照歯のエナメル小柱上面観は規則正しく魚鱗状に配列し, 小柱間隙は酸に強く脱灰され幅が広く, 割断面での最表層の無小柱エナメル様の部分は粗であった。斑状歯では, 小柱体が不規則な配列で毛様に残存し, 小柱間隙は狭く, 割断面では比較的平滑であった。CMR像では, 表層の高石灰化層にさらに著しい石灰化の部分が点在していた。以上から, エナメル小柱の構造が酸による脱灰に抵抗していると考えられた。なお, 歯のフッ素症患者の生活環境水中のフッ素の定量分析の結果では6.1-6.7ppmで, 本症の重要な発現因子と考えられた。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"9 1","pages":"72-82"},"PeriodicalIF":0.0,"publicationDate":"2001-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84176230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of the Posterior Margin of the Denture on the Functional Properties of Swallowing. 2. Decrease in Bolus Volume for One Swallowing and Prolongation of the Interval between Swallows in Forced, Repetitive Swallowing. 义齿后缘对吞咽功能特性的影响。在强迫、重复吞咽中，一次吞咽量减少，吞咽间隔时间延长。

Japanese Journal of Oral Biology Pub Date : 2001-01-01 DOI: 10.2330/JORALBIOSCI1965.43.392

K. Hiraba, Nobuhiro Hasegawa, Yoshinori Desaki, Norie Nozaki, T. Ishida, Yoshinobu Tanaka

{"title":"Effects of the Posterior Margin of the Denture on the Functional Properties of Swallowing. 2. Decrease in Bolus Volume for One Swallowing and Prolongation of the Interval between Swallows in Forced, Repetitive Swallowing.","authors":"K. Hiraba, Nobuhiro Hasegawa, Yoshinori Desaki, Norie Nozaki, T. Ishida, Yoshinobu Tanaka","doi":"10.2330/JORALBIOSCI1965.43.392","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.392","url":null,"abstract":"義歯床の後縁の長さが嚥下運動に及ぼす影響を検索する目的で, Ah-lineより後方1.5, 1.0, 0.5, 0cmの4段階の口蓋床を装着させ, その影響を最大嚥下量, 1回嚥下量, 嚥下間隔に着目し, 含水嚥下と連続嚥下の異なる2種類の嚥下運動にて検討した。その結果, 口蓋床の影響は1.5cmの長さのときに最も強い影響が認められ, 後縁の短縮に伴いその影響は順次減少したが, その様相は含水嚥下と連続嚥下とで明らかに異なった。含水嚥下での嚥下間隔は口蓋床の影響をほとんど受けなかったのに対して, 連続嚥下では1.5cmの長さの口蓋床においてコントロール比127.8%もの有意な延長をきたした。また連続嚥下での1回嚥下量は0cmでもコントロールのレベルにまで回復しなかった。一方, 口蓋粘膜の浸潤麻酔は, 連続嚥下での1回嚥下量, 嚥下間隔に対してまったく影響を及ぼさなかったことより, 口蓋床の影響は口蓋粘膜からの感覚情報を遮断した結果ではなく, 舌ならびに軟口蓋などの関係部位の運動を物理的に妨げた結果であると結論した。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"65 1","pages":"392-401"},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84451247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional Roles of Arg-gingipain and Lys-gingipain as Processing Enzymes for Various Cell Surface Proteins in Porphyromonas gingivalis 精氨酸-牙龈蛋白酶和赖氨酸-牙龈蛋白酶在牙龈卟啉单胞菌多种细胞表面蛋白加工酶中的功能作用

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.536

T. Kadowaki

{"title":"Functional Roles of Arg-gingipain and Lys-gingipain as Processing Enzymes for Various Cell Surface Proteins in Porphyromonas gingivalis","authors":"T. Kadowaki","doi":"10.2330/JORALBIOSCI1965.42.536","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.536","url":null,"abstract":"歯周病原性細菌として有力視されているPorphyromonas gingivalis(以下,P . gingivalis)は,種々のタンパク質分解酵素(プロテアーゼ)を菌体表面や菌体外に産生している。これらプロテアーゼは生体のさまざまなタンパク質を分解することから,病原性との相関が指摘されてきた1-9)。近年,本菌の主要なプロテアーゼ活性であるトリプシン様活性が2つの酵素Arg-gingipain (Rgp)とLys-gingipain (Kgp)によるものであることが明らかとなり,これらのビルレンス因子としての重要性が注目されている。RgpおよびKgpは,いずれもSH還元剤で著しく活性化されるシステインプロテアーゼであるが,切断部位がそれぞれ,Rgpはアルギニン残基の , Kgpはリジン残基のC末端側に特異的であるという特徴をもつ10,11)。P. gingivalis由来のさまざまなビルレンス因子は,生体にとって病原性を示す一方で,P. gingivalis自身にとっては生存・増殖のために必須であると考えられる。Rgp・Kgpもエネルギー・栄養源としてのアミノ酸・ペプチドを生成するという役割のほかにも, いくつかの自己タンパク質に対してプロセシング酵素として働くことによりそれらの成熟化ならびに活性化を調節していることがわかり,これら酵素の生理的重要性が明らかにされつつある。本稿では,RgpおよびKgpのP . gingivalisにおける生理的機能と歯周病の病態とのかかわりについて最近の知見をまとめた。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"32 1","pages":"536-545"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81781877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inhibitory Effects of Dequalinium Chloride and Domiphen Bromide on Caries Development in Rats Inoculated with Streptococcus sobrinus 6715 氯化去qualinium and Domiphen Bromide对接种sobrinus Streptococcus 6715大鼠龋发育的抑制作用

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.601

Yasunori Nakamura, H. Kuwashima, Tomohiko Kimura, S. Aoki

{"title":"Inhibitory Effects of Dequalinium Chloride and Domiphen Bromide on Caries Development in Rats Inoculated with Streptococcus sobrinus 6715","authors":"Yasunori Nakamura, H. Kuwashima, Tomohiko Kimura, S. Aoki","doi":"10.2330/JORALBIOSCI1965.42.601","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.601","url":null,"abstract":"非水溶性グルカン合成抑制作用と抗菌作用を有する塩化デカリニウム (DC) と臭化ドミフェン (DB) がう蝕抑制効果をもつか否かを, S. sobrinus 6715株接種ラットを用い, DC, DBそれぞれの0.02%水溶液と水道水 (Cont.) を飲料水として各々54日間給与するう蝕実験で調べた。その結果, S. sobrinusの歯面付着菌量は, Cont. 群に比べ0.02%DC群, 0.02%DB群では試験中期, 後期のいずれの時期においても著明に減少した。う蝕罹患度は, 隣接面では0.02%DC群, Cont. 群, 0.02%DB群の順で低かったが, 平滑面および裂溝部ではCont. 群に比べ0.02%DB群, 0.02%DC群のいずれも明らかに低かった。これらの各部位におけるう蝕スコアーを群別に総計した比較では, Cont. 群のう蝕発生率に対し, 0.02%DC群では68%, 0.02%DB群で34%のう蝕抑制が認められた。本実験条件下ではDBおよびDCの経口毒性はないと思われた。以上の成績から, DC, DBは細菌の歯面への付着を抑制して抗う蝕効果を示すと考えられた。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"73 1","pages":"601-608"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89466807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of Noggin Gene during Development of Maxillofacial Region in Mice Noggin基因在小鼠颌面部发育过程中的表达

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.563

T. Inage, T. Nakada, D. Kamogawa, Yutaka Sakaguchi, Michitomo Sato, M. Ono, H. Kamogawa, T. Sekiwa, M. Terakado, F. Kuwata, Yoshinori Sato, S. Oida

引用次数: 1

Neuropeptide, Substance P Modulates Bone Metabolism 神经肽，P物质调节骨代谢

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.527

T. Goto

引用次数: 0

Phylogenetic Analysis of 16S rDNA of Eubacterium exiguum and the Species-specific Regions for Primer Designation 出口真杆菌16S rDNA的系统发育分析及引物指定区

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.555

T. Hashimura, Michiko Sato, F. Nakazawa, E. Hoshino

引用次数: 0

Remineralization Effect of Xylitol Chewing Gum Containing Gloiopeltis furcata Extract and Calcium Hydrogenphosphate on Initial Caries-like Enamel Lesions 木糖醇口香糖对初发龋样牙釉质损伤的再矿化作用

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.590

Y. Saeki, Mitsuru Takahashi, Shingo Kamikawa, Takumi Tokumoto, Y. Miake, S. Yamada, K. Okuda, T. Yanagisawa

{"title":"Remineralization Effect of Xylitol Chewing Gum Containing Gloiopeltis furcata Extract and Calcium Hydrogenphosphate on Initial Caries-like Enamel Lesions","authors":"Y. Saeki, Mitsuru Takahashi, Shingo Kamikawa, Takumi Tokumoto, Y. Miake, S. Yamada, K. Okuda, T. Yanagisawa","doi":"10.2330/JORALBIOSCI1965.42.590","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.590","url":null,"abstract":": The objective of the present study was to investigate the beneficial effects of xylitol chewing gum containing Gloiopeltis furcata extract and calcium hydrogenphosphate on remineralization of initial caries like enamel lesions. Initial caries-like enamel lesions were artificially prepared by demineralizing human enamel blocks with a O.01M acetate buffer (pH 4.0) at 50℃ . We investigated sucrose gum (control), xylitol gum, and xylitol gum containing G. furcata extract and calcium hydrogenphosphate . In the in vitro intvestiga- tion,the enamel blocks having initial caries-like enamel lesions were immersed in a remineralizing solution containing the extract of each chewing gum at 37℃ for 2 weeks , and then evaluated for degrees of remineralization by contact microradiography . The remineralizing potential of each chewing gum in vivo was also evaluated by an oral device fixed with artificially demineralized human enamel block. Each subject was fixed on this device on the lingual surface of the mandibular molar for one week , and was given chewing gum samples 7 times a day. This in vivo study was carried out by the double-blind method .","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"2 1","pages":"590-600"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79699011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Vascularization of an Unsuccessful Case Following Guided Bone Regeneration 引导骨再生失败病例的血管化

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.573

M. Matsuo, C. Su, M. Saito, Y. Kishi, Kazuto Takahashi

{"title":"Vascularization of an Unsuccessful Case Following Guided Bone Regeneration","authors":"M. Matsuo, C. Su, M. Saito, Y. Kishi, Kazuto Takahashi","doi":"10.2330/JORALBIOSCI1965.42.573","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.42.573","url":null,"abstract":"This study evaluated a case which was unsuccessful after guided bone regeneration (GBR) operation with non-resorbable barrier membranes in the extraction socket of a beagle dog. To clarify the relationship between bone and vascular regeneration, a vascular resin cast model was observed under a scanning electron microscope (SEM).At 30 days post-operation, vessels from the periosteum were seen migrating to the socket through the gap between the membrane and the bone wall. The regenerated bone height was no higher than that of the pre-existing alveolar crest.At 60 days post-operation, the height of the regenerated bone was in accordance with that of the Pre-existing bone. A vascular network of granulation tissue was seen between the membrane and the upper margin of the alveolar bone. This vascular network consisted of a densely arranged vascular loop. The tracing of the circulatory pathway revealed that this network was composed of arteries from the alveolar bone marrow and veins of large diameter, which drained to the oral mucosa. The surface of a granulation tissue vessel showed a rough configuration. Resin was found to be leaking from the vascular loops.The study of this unsuccessful case clearly showed that the membrane was neither in close contact to the surrounding bone wall nor sufficiently supported by it. This resulted in an ingrowth of vessels from the periosteum to the socket. Consequently, there was no increase in bone height growth and new bone apposition did not occur. To succeed with GBR, it is essential that vascularization of the periosteum occur and that the membrane gradually cover and seal the extraction socket.","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"2017 1","pages":"573-579"},"PeriodicalIF":0.0,"publicationDate":"2000-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86760384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Effects of Xylitol on Remineralization of Artificial Demineralized Enamel 木糖醇对人工脱矿牙釉质再矿化的影响

Japanese Journal of Oral Biology Pub Date : 2000-12-20 DOI: 10.2330/JORALBIOSCI1965.42.580

Y. Miake, T. Yanagisawa

引用次数: 4