Iranian Endodontic Journal最新文献

{"title":"Erratum.","authors":"","doi":"10.22037/iej.v20i1.47188","DOIUrl":"https://doi.org/10.22037/iej.v20i1.47188","url":null,"abstract":"","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endodontic Treatment of an Upper Lateral Incisor with Oehlers' Type II Dens Invaginatus: A Case Report.","authors":"Ary Alves Mesquita-Júnior, Suelem Brenda Dos Santos, Rebeka de Oliveira Reis, Ingrid Luiza Mendonça Cunha, Aida Renée Assayag Hanan, Emílio Carlos Sponchiado-Júnior","doi":"10.22037/iej.v20i1.46131","DOIUrl":"10.22037/iej.v20i1.46131","url":null,"abstract":"<p><p>Dens invaginatus is a developmental malformation that is caused by the invagination of the enamel organ into the internal region of the dental papilla before tissue calcification. The aim of the present report is to discuss a clinical case of endodontic treatment of tooth #12, using bioceramic sealer. The extraoral examination revealed atypical anatomy, while vitality and percussion tests were negative, palpation test was positive. Edema was observed in the adjacent gingival mucosa. Based on clinical and tomographic findings, the diagnosis was pulp necrosis with chronic periapical abscess and Oehlers' type II dens invaginatus. In the first session, access surgery was performed with spherical drills with the aid of an operating microscope (OM) and an ultrasonic diamond tip. Four canals were located, and they were partially debrided and medicated. In the second session, odontometry and chemical-mechanical preparation with nickel-titanium instruments were performed. The irrigation solution was 2.5% sodium hypochlorite. The root canals were filled with calcium hydroxide paste and the chamber was temporarily sealed. During the third session, ultrasonic irrigation was applied for final washing and the root canals were filled with Bio-C sealer using the classic single-cone technique. At 6-month follow-up, the tooth was asymptomatic and the radiography revealed significant bone repair. It was concluded that tomography, operating microscope, ultrasonic irrigation, and materials with greater flow, such as bioceramic sealers, enhanced the clinical success of the clinical case.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e7"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11808323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Critical Review of the Role of Geristore® in Contemporary Endodontics.","authors":"Mahsa Radafshar, Ardavan Parhizkar","doi":"10.22037/iej.v20i1.48268","DOIUrl":"10.22037/iej.v20i1.48268","url":null,"abstract":"<p><strong>Introduction: </strong>Geristore® (GS) is an advanced dual-cure resin-modified glass ionomer with favourable biological and physical properties, including biocompatibility, fluoride release, and excellent sealing ability. Originally developed for restorative purposes, its clinical versatility has nonetheless extended into endodontics. The current critical review primarily aims to evaluate the biological characteristics, endodontic applications, and possible clinical potential of GS as a biomaterial in modern endodontic practice.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted across major databases (MEDLINE, PubMed, Scopus, Cochrane, EMBASE, Google Scholar, and grey literature) without restrictions on date and/or language. Relevant peer-reviewed studies on the composition, properties, and endodontic uses of GS were identified, screened, investigated, and critically analysed.</p><p><strong>Results: </strong>Geristore® has demonstrated promising outcomes in endodontic procedures, <i>e.g</i>., root-end filling, perforation repair, vital pulp therapy, retrograde vital pulp therapy, intra-orifice barrier placement and the management of external cervical resorption, Additionally, various studies have highlighted its favourable soft tissue compatibility, sealing ability (even in moist environments) as well as its acceptable mechanical properties. However, certain limitations, including reduced flexural strength and higher cytotoxicity compared to calcium silicate-based materials, such as mineral trioxide aggregate, have been reported.</p><p><strong>Conclusion: </strong>Geristore® presents as a clinically useful alternative for specific endodontic indications where biocompatibility, sealability, and ease of handling seem critical. However, further high-quality clinical trials and comparative studies are essential to validate its long-term performance and establish its role relative to established endodontic biomaterials.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Zinc Oxide Nanoparticles on Calcium-enriched Mixture Cement: Physical, Chemical, and Mechanical Properties.","authors":"Mohammadreza Nabavizadeh, Abbas Abbaszadegan, Fatemeh Zebardast","doi":"10.22037/iej.v20i1.46475","DOIUrl":"10.22037/iej.v20i1.46475","url":null,"abstract":"<p><strong>Introduction: </strong>Calcium-enriched mixture (CEM) cement is a water-based biomaterial with properties similar to calcium silicate-based cements (CSCs). Zinc oxide (ZnO), a bioactive material widely used for its antimicrobial properties and beneficial biological effects on body tissues, was incorporated into CEM cement in this study. The objective was to evaluate the impact of ZnO nanoparticles (ZON) on the physical, chemical, and mechanical properties of CEM cement.</p><p><strong>Materials and methods: </strong>ZON powder was blended with CEM cement powder at a 10% weight ratio. The mixture was combined with liquid (1 g powder: 0.33 mL liquid) and cast into test-specific molds. Samples of original CEM cement without ZON served as the control group. The samples were evaluated for changes in setting time (<i>n</i>=6), compressive strength (<i>n</i>=6), solubility (<i>n</i>=10), and pH (<i>n</i>=10).</p><p><strong>Results: </strong>The initial setting time was identical in both groups. ZON incorporation reduced the secondary setting time, though not significantly. Compressive strength remained unchanged. After 7 days, solubility increased significantly in ZON-containing samples. While ZON reduced the pH of CEM cement in deionized water after 5 hours, no significant difference was observed at 24 hours.</p><p><strong>Conclusion: </strong>Incorporating ZON into CEM cement caused minor changes, including a reduced secondary setting time, increased solubility, and transient pH changes, without significantly affecting overall performance.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e23"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of a Late Complication of Strip Perforation with Overextended Gutta-percha Using Intentional Replantation: A 10-Year Follow-up Case Report.","authors":"Saeed Asgary","doi":"10.22037/iej.v20i1.48363","DOIUrl":"10.22037/iej.v20i1.48363","url":null,"abstract":"<p><p>Strip perforation is a severe procedural complication during root canal therapy, often associated with poor prognosis, especially when combined with overextended gutta-percha. While surgical or nonsurgical retreatment is commonly indicated, patient-centered decision-making and long-term follow-up may influence the management strategy. This case report describes the conservative follow-up and eventual successful treatment of a mandibular second molar with an extensive midroot strip perforation and extruded gutta-percha, ultimately managed with intentional replantation and root-end filling using calcium-enriched mixture (CEM) cement. In 2015, a 40-year-old female patient presented for routine examination. A previously treated mandibular second molar (#37), which had a severe strip perforation in the mesial root and overextended gutta-percha one year prior, remained asymptomatic and functional. The patient declined retreatment and opted for annual monitoring. Over five years, the tooth remained functional and symptom-free, and the extruded gutta-percha showed gradual radiographic resorption. In 2023, the patient returned with a symptomatic apical periodontitis and a large periapical lesion associated with the same tooth. Intentional replantation was performed with midroot resection of the mesial root, root-end filling using CEM cement, and immediate replantation. At the 1-year follow-up, the tooth remained functional, asymptomatic, and radiographically healed. The case highlights the long-term clinical risks of untreated strip perforations, the unpredictable resorption of overextended materials, and the efficacy of minimally invasive surgical interventions in preserving tooth function.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Surgical Management of a Mandibular First Molar with Strip Perforation, Separated File, and Canal Ledge: A Case Report.","authors":"Amir Hosein Mehdizadeh, Fatemeh Soltani, Motahareh Yusefi, Razieh Sadeghi, Arash Shahravan","doi":"10.22037/iej.v20i1.48539","DOIUrl":"10.22037/iej.v20i1.48539","url":null,"abstract":"<p><p>Root canal mishaps such as perforations, separated instruments, and canal ledges remain significant challenges in endodontic retreatment. This case report describes the successful non-surgical management of a mandibular first molar presenting with a strip perforation in the mesiobuccal canal, a separated file in the mesiolingual canal, and a ledge in the distal canal. The tooth was generally asymptomatic with only mild sensitivity to percussion, without any pockets of endodontic origin. Radiographic examination revealed periapical and furcation radiolucencies. The tooth had a previous endodontic treatment with an infected root canal system and chronic apical periodontitis. Notably, the tooth was left undressed for approximately three months following the initial mishap, negatively influencing prognosis. Nonetheless, considering the patient's preference and the favorable periodontal and restorative conditions, non-surgical retreatment was initiated. Treatment included thorough chemomechanical preparation, bypassing the separated file and ledge, and sealing the perforation with calcium-enriched mixture cement. The tooth was subsequently restored with bonded composite resin. At 12-month follow-up, radiographic signs of healing were evident, and at 18 months, the tooth remained asymptomatic with no clinical or radiographic signs of apical or furcation pathology.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12554239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145377286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Centering Ability in Artificially Curved Canals with Three Thermomechanically Treated NiTi Instruments: Blue, Pink and Gold.","authors":"Alejandro Félix, José Aranguren, Natalia Navarrete, Alejandro R Pérez","doi":"10.22037/iej.v20i1.44025","DOIUrl":"10.22037/iej.v20i1.44025","url":null,"abstract":"<p><strong>Introduction: </strong>The present study aimed to evaluate the instrumentation time and transportation ability of three file sequences sharing the same physical properties (diameter, tip design, cross-sectional shape, and taper), each manufactured entirely of one single alloy type (Pink, Blue, or Gold).</p><p><strong>Materials and methods: </strong>One hundred and eighty simulated curved resin canals were instrumented using the BlueShaper system, with full Z1-Z4 sequences, each made entirely of a single alloy type (Pink, Blue, or Gold). Images before and after instrumentation of each specimen were overlaid with Photoshop software to evaluate centering ability in the coronal, middle, and apical thirds. Data were analyzed using one-way analysis of variance (ANOVA) with post hoc multiple comparisons or the non-parametric Kruskal-Wallis test for intergroup analysis.</p><p><strong>Results: </strong>No significant differences were found between the different alloys in the centering ability of the simulated canals in the coronal third (<i>P</i>>0.05). The Blue alloy of the BlueShaper system showed significantly less transport ability in the middle third than Pink and Gold alloys (<i>P</i><0.05). A significantly lower centering ability (<i>P</i><0.001) was observed in the apical third between the Blue and Pink alloys than the Gold alloy.</p><p><strong>Conclusions: </strong>It was concluded that the Blue alloy performed better than the Pink and Gold alloys in the middle and apical thirds. The pink alloy performed better than the Gold alloy in the apical third.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e39"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12554235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145377213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytotoxicity of Calcium Silicate-Based Cements: Role of Bonding Time, Strategy, and Thickness in an In Vitro Model.","authors":"Narges Panahandeh, Maryam Torshabi, Roja Askian, Hassan Torabzadeh, Saeed Asgary","doi":"10.22037/iej.v20i1.46162","DOIUrl":"https://doi.org/10.22037/iej.v20i1.46162","url":null,"abstract":"<p><strong>Introduction: </strong>This <i>in vitro</i> study assessed the effects of bonding application time (immediate vs. 24-hour delay) and strategy [self-etch (SE) vs. etch-and-rinse (ER)] on cytotoxicity of three calcium silicate-based cements [calcium-enriched mixture (CEM) cement, ProRoot mineral trioxide aggregate (MTA) and Biodentine] at 1mm and 2mm thicknesses.</p><p><strong>Materials and methods: </strong>Specimens (<i>n</i>=20 per group) were fabricated using CEM, MTA, and Biodentine. Scotchbond Universal was applied immediately or after 24 hours via SE or ER strategies. Cytotoxicity of cement extracts (100%, 50%, and 25% concentrations) on human gingival fibroblasts was evaluated using methyl thiazolyl tetrazolium (MTT) assay. Data were analyzed with four-way ANOVA and Tukey's test (<i>P</i>≤0.05).</p><p><strong>Results: </strong>The biomaterials showed comparable cytotoxicity (<i>P</i>>0.05), with toxicity decreasing progressively at lower concentrations (25% <50%<100%). At 100% concentration, ER bonding significantly improved cell viability for CEM (<i>P</i><0.05), while immediate bonding of 1-mm specimens increased cytotoxicity (<i>P</i><0.05). Immediate SE bonding of 1-mm MTA and Biodentine specimens also resulted in higher cytotoxicity (<i>P</i><0.05). At 50% concentration, SE strategy and 1-mm thickness increased cytotoxicity, with bonding time effects significant only in ER mode. No significant differences were observed at 25% concentration (<i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Delayed bonding (24 hours), ER strategy, and ≥2-mm thickness minimize cytotoxicity of calcium silicate-based cements. Clinically, immediate permanent restoration after vital pulp therapy is viable when considering these parameters, eliminating the need for interim protective layers (<i>e.g</i>., glass ionomer bases).</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tomographic Study of the Internal Anatomy of Mandibular Third Molars Based on Vertucci's Classification.","authors":"André Santos de Almeida, Raissa Barreto Tavares, Samuel Rodrigo de Andrade Veras, Adriano Referino da Silva Sobrinho, Hugo Angelo Gomes de Oliveira, Arnaldo de França Caldas Júnior, Gustavo Pina Godoy, Manuela Medeiros de Menezes Xavier, Jackeline Mayara Inácio Magalhães","doi":"10.22037/iej.v20i1.49495","DOIUrl":"10.22037/iej.v20i1.49495","url":null,"abstract":"<p><strong>Introduction: </strong>Knowledge of the internal anatomy of mandibular third molars is essential for successful endodontic treatment, yet their complex morphology often complicates management. This study evaluated the root canal morphology of mandibular third molars using cone-beam computed tomography (CBCT) according to Vertucci's classification.</p><p><strong>Materials and methods: </strong>A total of 653 CBCT scans were screened, and 274 mandibular third molars meeting the inclusion criteria were analyzed. Root canal configurations were classified according to Vertucci, with atypical cases recorded as \"type 0\" for statistical purposes. Data were analyzed with Fisher's exact test (α=0.05).</p><p><strong>Results: </strong>Vertucci type I was the most prevalent configuration (62.8%), followed by type V (17.4%). Sex and dental arch side significantly influenced the distribution of configurations (<i>P</i>=0.044 and <i>P</i>=0.013, respectively), while age did not (<i>P</i>=0.569). Distal and distolingual roots were predominantly type I, whereas mesial roots showed greater variability, particularly between sexes.</p><p><strong>Conclusion: </strong>Mandibular third molars exhibit considerable anatomical variation, with types I and V being most frequent. Patient sex and arch side significantly affect root canal morphology, underscoring the importance of detailed preoperative assessment with CBCT for accurate endodontic planning.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12554240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145377319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal Behavior Variations among Commercial Gutta-percha Brands: An Optical Thermography Study.","authors":"Moisés Uzal, José Aranguren, Alejandro R Pérez, Ana Ramírez-Muñoz, Natalia Navarrete","doi":"10.22037/iej.v20i1.45131","DOIUrl":"https://doi.org/10.22037/iej.v20i1.45131","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to assess the thermal behavior of five different commercial gutta-percha brands using optical thermography. We focused on temperature differences and heat transfer characteristics at different apical distances.</p><p><strong>Materials and methods: </strong>Gutta-percha cones from the following brands were tested: Autofit Greater Taper, Protaper Gold F2, TruNatomy Prime, ZARC Gutta-percha points # 25/0.06, and Reciproc Blue R25. A specific heating system was used to subject the cones to thermal imaging. Measurements were taken at 1-, 2-, 3-, and 4-mm apical distances for 5 mm and 10 mm cone lengths. Statistical analyses included Student's t-tests and Analysis of Variance with the significance level set at 0.05.</p><p><strong>Results: </strong>Upon intragroup comparison, we found subtle distinctions in thermal behavior when examining gutta-percha cone lengths (5 mm <i>versus</i> 10 mm). TruNatomy exhibited statistically significant variations (<i>P</i><0.05) at 2- and 3-mm distances. Conversely, ZARC and Reciproc Blue R25 displayed notable differences (<i>P</i><0.05) at 2-, 3-, and 4-mm distances. In contrast, Autofit Greater Taper and Protaper Gold F2 consistently diverged across all distances (<i>P</i><0.05). In intergroup comparisons of 5 mm length, significant variances (<i>P</i><0.05) emerged among brands at 1- and 2-mm distances. At 10 mm length, TruNatomy differed significantly (<i>P</i><0.05) from other brands across all distances. The heat tip maintained an average maximum temperature of 154.54^°C.</p><p><strong>Conclusion: </strong>Thermal behavior of gutta-percha brands varied significantly, with implications for endodontic treatments. While differences were observed in heat transfer and maximum temperatures, all brands remained within safe temperature ranges for clinical use. Understanding these variations can aid clinicians in selecting appropriate gutta-percha for specific clinical scenarios, ultimately optimizing root canal obturation quality.</p>","PeriodicalId":14534,"journal":{"name":"Iranian Endodontic Journal","volume":"20 1","pages":"e16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}