International Ophthalmology最新文献

{"title":"Bibliometric analysis of published works in ocular trauma: a growing focus on open globe injury.","authors":"Hassaam S Choudhry, Eric J Kuklinski, Allen Fu, Param Shukla, Matthew Montani, Fareeda Eraky, Marco A Zarbin, Paul D Langer, Neelakshi Bhagat","doi":"10.1007/s10792-025-03417-5","DOIUrl":"https://doi.org/10.1007/s10792-025-03417-5","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to analyze the trends and characteristics of ocular trauma research published from 2000 to 2022 to delineate the trajectory of the field's research, provide information about the network of key contributors, and help determine future research strategies and direction.</p><p><strong>Methods: </strong>Web of Science was queried for published works using a series of keywords relating to ocular trauma: \"globe rupture\", \"ruptured globe\", \"globe injury\", \"ocular trauma\", \"intraocular foreign body\", \"eye trauma\", \"eye injury\", and \"traumatic endophthalmitis\". All article information was compiled using the VOSviewer software. Article information analyzed included year of publication, publishing journal, author, institution, country, and keywords/key terms.</p><p><strong>Results: </strong>A total of 3362 articles were identified. In the time period studied, there is a noticeable trend for an increase in the number of papers pertaining to ocular trauma to be published annually. The journal, Eye published the most, and the United States produced the most articles of any country. Important keywords other than \"ocular trauma\" included \"epidemiology\", \"management\", \"children\", \"vitrectomy\" and \"endophthalmitis\".</p><p><strong>Conclusion: </strong>Complications due to ocular trauma are seen worldwide. Many different institutions, journals, and countries have published research on ocular trauma with an increased frequency in recent years. This study provides valuable information on the status of scholarly investigation of ocular trauma in the last 2 decades and sheds light on the trajectory of recent research interest.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"47"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional semi-autotamatic segmentation of nasolacrimal duct morphometry on computed tomography images.","authors":"Kadriye Betul Pence, Nureda Nalcaci Bozkurt, Bahar Tekin, Selva Sen, Gamze Ansen, Tugrul Ormeci, Neslihan Yuzbasioglu","doi":"10.1007/s10792-025-03416-6","DOIUrl":"https://doi.org/10.1007/s10792-025-03416-6","url":null,"abstract":"<p><strong>Purpose: </strong>Given the potential role of nasolacrimal duct (NLD) morphometry in the aetiology of primary acquired obstructions, it is imperative that clinicians have access to detailed anatomical information. The aim of this study was to determine normative data on nasolacrimal duct morphometry in the Turkish population sample and to provide guidelines for clinicians.</p><p><strong>Methods: </strong>The study included retrospectively computed tomography images of a healthy Turkish population sample of 151 individuals, 79 of whom were female and 72 of whom were male. Images were modeled and analyzed using 3D Slicer version 5.2.2.</p><p><strong>Results: </strong>The total volume and area of the NLD were smaller in females than in males. The right- and left-sided volume of the NLD were smaller in females than in males (In male, right side 219.28 ± 77.53 mm³ and left side 213.14 ± 73.82 mm³; in female, right side 193.82 ± 75.71 mm³, left side, 190.34 ± 82.54 mm³). Although the anteroposterior and transverse diameters of the right-sided NLD were not statistically different between the genders, the anteroposterior and transverse diameters of the left-sided NLD and distance between right and left NLD were smaller in female than in males. The volume and surface area of the right-sided NLD and the distance between the right and left NLD were larger with increasing age. The anteroposterior diameter was observed to be larger on the right side than on the left in both sexes, whereas the transverse diameter was larger on the right side than on the left side exclusively in females.</p><p><strong>Conclusion: </strong>The results of this study may assist clinicians in the surgical approaches.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"46"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary steroids in acute central serous chorioretinopathy.","authors":"Dmitrii S Maltsev, Alexei N Kulikov, Alexander S Vasiliev, Jay Chhablani","doi":"10.1007/s10792-025-03422-8","DOIUrl":"https://doi.org/10.1007/s10792-025-03422-8","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze levels of salivary steroids, including 17-OH-progesterone (17-OHP), androstenedione, dehydroepiandrosterone, cortisol, cortisone, progesterone, testosterone, and estradiol, in patients with acute central serous chorioretinopathy (CSCR) patients.</p><p><strong>Methods: </strong>Acute CSCR patients and healthy individuals were included in this observational case-control study. Levels of salivary steroids were determined by high-performance liquid chromatography with tandem mass spectrometry detection. Clinical characteristics of CSCR patients were assessed based on multimodal imaging.</p><p><strong>Results: </strong>Seventeen CSCR patients (40.1 ± 4.6 years) and fourteen age-matched healthy controls (40.6 ± 3.8 years) were included. Mean central retinal thickness and subfoveal choroidal thickness in affected eye of CSCR patients were 436.2 ± 131.1 µm and 464.6 ± 132.6 µm, respectively. Mean best-corrected visual acuity was 0.09 ± 0.11 LogMAR. Mean symptoms duration before saliva collection was 0.9 ± 0.6 months. 17-OHP was decreased compared to the normal limits established in healthy controls in 10 out of 17 patients (59%), androstenedione in 15 out of 17 patients (88%), dehydroepiandrosterone in 10 out of 17 patients (59%), cortisol in 6 out of 17 patients (35%), cortisone in 12 out of 17 patients (83%), progesterone in 9 out of 17 patients (53%), testosterone in 10 out of 17 patients (59%), and estradiol in 5 out of 17 patients (29%). In total, among CSCR patients lower level in saliva was found for all studied hormones (p < 0.05), except progesterone and estradiol.</p><p><strong>Conclusion: </strong>Salivary steroids are decreased in acute CSCR male patients compared with age-matched controls. This may indicate inhibition of steroidogenesis caused by chronic stress and personal reactivity preceding manifestation of CSCR.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"49"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported prevalence and risk factors associated with keratoconus among the adult population of Trinidad and Tobago: a cross-sectional study.","authors":"Ngozika Esther Ezinne, Michael Agyemang Kwarteng, Khathutshelo Percy Mashige, Vanessa R Moodley","doi":"10.1007/s10792-025-03414-8","DOIUrl":"https://doi.org/10.1007/s10792-025-03414-8","url":null,"abstract":"<p><strong>Aim: </strong>To determine the prevalence of keratoconus and its associated risk factors within the adult population of Trinidad and Tobago.</p><p><strong>Method: </strong>A population-based cross-sectional study was conducted among adults in Trinidad and Tobago, utilizing the Keratoconus Risk Assessment Questionnaire (KRIS) for data collection. Data were exported to the Statistical Package for Social Sciences (SPSS) version 27 for analysis. Descriptive statistics were employed to summarize the variables, while logistic regression was used to identify associated risk factors, with a significance level set at p < 0.05.</p><p><strong>Results: </strong>A total of 413 participants were included in the study, yielding a response rate of 97.4% (413/424). The prevalence of keratoconus (KC) was 1.5% (95% CI: 0.33 - 2.67%). The condition was more prevalent among females (98.5%), individuals aged 19-30 years (66.7%), and participants of mixed race (50%). Allergic or atopic diseases were identified as the most common established risk factor for KC, affecting 50.1% of all participants. Among those diagnosed with KC, eye rubbing emerged as the most common established risk factor. Family history of KC (95% CI: 1.841-48.352, p < 0.007) and the use of rigid contact lenses (95% CI: 8.696-286.051, p < 0.001) were statistically significant predictors of KC. Specifically, participants with a family history of KC were 49.8 times more likely to develop the condition (OR = 49.875), while those using rigid contact lenses were 9.4 times more likely (OR = 9.436).</p><p><strong>Conclusion: </strong>The prevalence of KC in Trinidad and Tobago was found to be significant. Among the identified risk factors, atopy was the most common. Additionally, a positive family history and the use of rigid contact lenses were significant predictors of KC. Early screening for keratoconus in this country is strongly recommended to facilitate prompt detection and appropriate management of the condition.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"44"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of inferior oblique anterior transposition on vertical deviation.","authors":"Rui Li, Shounan Qi, Chenguang Wang","doi":"10.1007/s10792-024-03396-z","DOIUrl":"https://doi.org/10.1007/s10792-024-03396-z","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and complications of simplified graded inferior oblique anterior transposition (IOAT) in treating at least 10 PD vertical deviation in the primary position and inferior oblique muscle overaction (IOOA).</p><p><strong>Methods: </strong>This retrospective study reviewed the medical records of 65 patients treated with simplified graded IOAT procedures for both vertical deviation and IOOA. Patients were grouped according to vertical deviation in the primary position. Group 1: vertical deviation of not > 20 PD; the inferior oblique (IO) muscle was fixed 2 mm posterior and 2 mm temporal to the inferior rectus insertion. Group 2: vertical deviation > 20 PD; the muscle was fixed at the level of insertion of the inferior rectus muscle. Postoperative outcomes in vertical deviation (≤ 5 PD, excellent; 5-10 PD, fair; > 10 PD, poor), IOOA, anti-elevation syndrome (AES), abnormal head position (AHP), V-pattern, and foveal disc angle (FDA) were assessed.</p><p><strong>Results: </strong>Patients were categorized as 43 (53.5% men) in group 1 and 22 (54.5% men) in group 2. IOAT improved vertical deviation, IO muscle function, AHP, V-pattern, and FDA. IOOA decreased from + 2.1 to 0.02 in group 1 and from + 2.4 to 0 in group 2. Mean vertical reduction after IOAT was 12.4 ± 3.8 and 23.8 ± 7.3 PD in groups 1 and 2, respectively. Excellent results were achieved in 83.7% and 77.3% of patients and fair results in 16.2% and 18.2%, respectively. Among the 48 asymmetric DVD patients, 83.8% and 82.3% in groups 1 and 2, respectively, achieved satisfactory results. No AES occurred in two groups.</p><p><strong>Conclusion: </strong>The simplified graded IOAT procedure, which is graded only on the basis of vertical deviation, can achieve satisfactory results for resolving IOOA with vertical deviation or DVD, AHP, V-pattern, and FDA. In addition, the modified procedure of fixing posterior fibers at a slight posterior tilt is clinically instructive in correcting vertical deviation > 20 PD while reducing AES complications.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"42"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SMILE for correction of myopia in patients during the incipient phase of presbyopia.","authors":"Ruiyu Zhang, Xiaorui Zhao, Yifei Yuan, Yu Zhang, Yueguo Chen","doi":"10.1007/s10792-025-03427-3","DOIUrl":"https://doi.org/10.1007/s10792-025-03427-3","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate clinical outcomes and visual quality 12 months after small incision lenticule extraction (SMILE) for correction of myopia with or without astigmatism in patients during the incipient phase of presbyopia.</p><p><strong>Setting: </strong>Peking University Third Hospital, Beijing, China.</p><p><strong>Design: </strong>Retrospective observation study.</p><p><strong>Methods: </strong>Patients who had SMILE for myopia and myopic astigmatism with binocular plano target refraction and aged between 39 and 45 years were included. Subjective refraction; distance, intermediate, and near visual acuities; defocus curve; anterior corneal surface aberrations and the Strehl ratio; accommodation function, and a subjective questionnaire assessing visual quality in real-life situations were evaluated 12 months postoperatively.</p><p><strong>Results: </strong>Clinical data of 29 cases were analyzed. The average patient age was 40.10 ± 0.94 years. The mean preoperative manifest refraction was - 4.73 ± 1.11 D (range: - 2.13 to - 6.13 D) of spherical equivalent in right eyes. At the 12-month follow-up, binocular uncorrected distance visual acuity and uncorrected intermediate visual acuity ≥ 20/20 were achieved in all patients, and 96.6% (28/29) of patients achieved uncorrected near visual acuity ≥ 20/25. SMILE induced a statistically significant increase in spherical aberration, coma, and total higher-order aberrations (P < 0.001). For accommodative function, only the negative relative accommodation improved significantly after surgery (P < 0.001). The questionnaire demonstrated high patient satisfaction with near vision, and no one reported having severe visual disturbance.</p><p><strong>Conclusion: </strong>SMILE appeared to be safe and effective in improving distance vision in patients during the incipient phase of presbyopia, and a satisfactory amount of near vision was maintained in this group of subjects.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"50"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drainage from intentional extramacular holes after internal limiting membrane insertion to treat macular hole retinal detachment in highly myopic eyes.","authors":"Zhijian Huang, Qin Ding, Xiao Chen, Li Zhu, Ying Yan, Miao Zeng, Cheng Hu, Nian Xiang","doi":"10.1007/s10792-025-03406-8","DOIUrl":"https://doi.org/10.1007/s10792-025-03406-8","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose is to evaluate the effect of drainage from intentional extramacular holes after internal limiting membrane insertion to treat macular hole retinal detachment (MHRD) in highly myopic eyes.</p><p><strong>Methods: </strong>This study is a retrospective, observational, and comparative case series that included 25 consecutive highly myopic eyes with MHRD. All eyes underwent standard 23-gauge vitrectomy, inverted internal limiting membrane insertion into the macular hole, subretinal fluid drainage from an intentionally created extramacular retinal hole, and tamponade with either silicone oil (SO group, n = 13) or perfluoropropane (C₃F₈ group, n = 12). A facedown position was maintained for 1 week postoperatively. The anatomic and functional outcomes were compared between two groups at the endpoint.</p><p><strong>Results: </strong>There was no significant difference in the retinal reattachment rate between the SO and C₃F₈ groups (100% and 91.67%, P = 0.48). The macular hole closure rates were 92.31% in the SO group and 100% in the C₃F₈ group (P = 0.52). The mean best-corrected visual acuity (BCVA) improved from 2.18 ± 0.60 logarithm of the minimum angle of resolution(logMAR) preoperatively to 1.11 ± 0.36 logMAR (P < 0.01) in the SO group and from 2.20 ± 0.61 to 1.29 ± 0.50 (P < 0.01) in the C₃F₈ group at the endpoint. There was no significant difference in BCVA improvement between the two groups (P = 0.37).</p><p><strong>Conclusion: </strong>The drainage technique from intentional extramacular holes after internal limiting membrane insertion is an effective treatment for MHRD in highly myopic eyes, regardless of whether silicone oil or gas is used as a tamponade.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"43"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of anterior chamber depth on corneal endothelium following phacoemulsification among patients with different axial lengths.","authors":"Moataz A Sallam, Khaled A Zaky","doi":"10.1007/s10792-025-03415-7","DOIUrl":"https://doi.org/10.1007/s10792-025-03415-7","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the effect of anterior chamber depth on corneal endothelium using specular microscopy following uneventful phacoemulsification among cataract patients with different axial lengths.</p><p><strong>Methods: </strong>The study was conducted in a quasi-experimental design including 300 eyes of 300 patients with grade three age-related nuclear cataract distributed equally based on their axial length into three equal groups. All eyes had grade three nuclear cataract. All patients underwent phacoemulsification using the same settings. They were assessed preoperatively and postoperatively at one week, one month and three months using specular microscopy. Outcome measures included endothelial cell density, axial length (AL), anterior chamber depth (ACD), ultrasound time (UST), cumulative dissipated energy (CDE) and intraoperative balanced salt solution (BSS) volume.</p><p><strong>Results: </strong>There were no significant differences (p > 0.05) between study groups regarding age, cataract density, UST, CDE and BSS volume. The endothelial cell density decreased significant (p < 0.001) postoperatively in all groups through the follow up period. However, the amount of change decreased as the end of follow up was approached. A significant negative correlation was found between amount of endothelial cell loss and ACD. However, no significant correlation existed between AL and ACD or ECL.</p><p><strong>Conclusions: </strong>Endothelial cell density changes were significant following phacoemulsification. These changes were more in patients with shallow anterior chamber regardless of the axial length. Surgeons should adjust their surgical pattern considering our results.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"45"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbital inflammatory disease: a joint clinical experience in rheumatology and ophthalmology.","authors":"Semih Gülle, Ceren Durmaz Engin, Denizcan Özizmirliler, Süleyman Men, Fatoş Önen, Meltem Söylev Bajin","doi":"10.1007/s10792-025-03419-3","DOIUrl":"https://doi.org/10.1007/s10792-025-03419-3","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective study aimed to characterize the clinical features, histopathological findings, and treatment outcomes of patients diagnosed with orbital inflammatory disease (OID) co-managed by the rheumatology and ophthalmology departments in a tertiary hospital.</p><p><strong>Methods: </strong>Medical records of 14 patients with OID were analyzed. Data on demographics, clinical presentation, laboratory investigations, radiological imaging, histopathological results, treatment regimens, and disease outcomes were collected and reviewed.</p><p><strong>Results: </strong>The mean age of the patients was 34.5 years, with a female (71.4%) predominance. Periorbital pain (62.5%), periorbital edema (50%) and diplopia (50%) were the most common presenting symptoms. Histopathological evaluation revealed diverse subtypes, including non-specific orbital inflammation (NSOI) (42.8%), orbital myositis (28.5%) and IgG4-related disease (14.3%). Initial treatment with systemic corticosteroids achieved remission in 14.3% of patients, while 85.7% required additional immunosuppressive therapy. Radiotherapy was effective in one patient unresponsive to steroid and azathioprine treatment.</p><p><strong>Conclusion: </strong>OID presents with diverse clinical manifestations and histopathological subtypes, often requiring multidisciplinary management. While corticosteroids remain the first-line therapy, adjunctive immunosuppressive agents or radiotherapy may be necessary in refractory cases.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"48"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of digital eye strain with central corneal thickness: a cross-sectional observational pilot study.","authors":"Rakesh Kumar Jha, Jaya Kaushik, Veerabhadhra Rao Bhavaraj, Bhupesh Bhatkoti","doi":"10.1007/s10792-025-03429-1","DOIUrl":"https://doi.org/10.1007/s10792-025-03429-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate whether the digital eye strain (DES) was associated with the low central corneal thickness (CCT).</p><p><strong>Methods: </strong>This observational cross-sectional pilot study was conducted from April 2023 to October 2023 at a tertiary eye care centre in North India, where CCT values were compared between subjects with DES and those without DES. Two hundred and eighty subjects (n = 280) aged 15-40 years with clear corneas and lenses were initially included in this study. Those with corneal opacity, corneal degeneration, pregnancy, and diabetes were excluded. These subjects were then assessed with a 'computer vision syndrome questionnaire (CVS-Q)' test. Participants having a score ≥ 6 were grouped as the \"DES group\" and participants having a score < 6 were grouped as the \"Control group\". The participants from each group were then examined with Spectral Domain Ocular Coherence Tomography (SD-OCT) to measure CCT. The primary outcome was to evaluate the comparative difference in CCT values between the two groups as well as the association of DES with CCT values.</p><p><strong>Results: </strong>The study included one hundred and forty (n = 140) subjects each in the DES group and the control group. The DES score assessed with the CVS-Q questionnaire ranged from 6 to 32 in the DES group, with a mean ± SD of 17.08 ± 7.01. The overall mean CCT was 507.31 ± 31.01 (median, 512 microns; range, 450-601 microns). There was a significant difference in the mean CCT between the two groups, with lower mean CCT values in the DES group (487.76 ± 23.61 microns) than the control group (526.87 ± 24.53 microns) (p < 0.0001). The CVS-Q test score had moderate inverse correlation in the DES group (Pearson's r = - 0.42, p < 0.01) and negligible correlation (Pearson's r = - 0.14, p = 0.12) in the control group with CCT.</p><p><strong>Conclusion: </strong>Central corneal thickness was observed to be reduced among the subjects with digital eye strain (DES).</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"52"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}