International Ophthalmology最新文献

{"title":"Explainable dual-stage context-aware SwinUNet for accurate optic disc and optic cup segmentation in glaucoma assessment.","authors":"P Gopi Kannan, C Balasubramanian, T Jarin","doi":"10.1007/s10792-026-04090-y","DOIUrl":"https://doi.org/10.1007/s10792-026-04090-y","url":null,"abstract":"<p><strong>Purpose: </strong>Accurate segmentation of glaucoma-related anatomical structures from retinal fundus images is crucial for reliable clinical assessment and early disease diagnosis. However, variations in illumination, low contrast, and complex structural patterns make precise boundary delineation of the optic disc (OD) and optic cup (OC) challenging. This study aims to improve the accuracy of OD and OC segmentation for glaucoma assessment.</p><p><strong>Methods: </strong>An Enhanced SwinUNet model is proposed, integrating hierarchical transformer-based feature extraction with a Dual-Stage Context-Aware Feature Refinement (DCF-Refine) module embedded in skip connections. A preprocessing stage is applied using CLAHE-based contrast enhancement in LAB color space along with min-max normalization to improve image quality and stabilize training. The model employs Swin Transformer (ST) blocks to capture both local structural details and long-range dependencies. The DCF-Refine module enhances feature fusion through sequential Spatial Context Refinement (SCR) and Channel Context Refinement (CCR).</p><p><strong>Results: </strong>Experimental evaluation on the Drishti-GS and REFUGE datasets demonstrates that the proposed Enhanced SwinUNet achieves superior performance compared to existing segmentation methods, attaining accuracies of 99.3% and 99.1%, respectively.</p><p><strong>Conclusion: </strong>The proposed model provides highly accurate and reliable segmentation of OD and OC structures, effectively addressing challenges in retinal image analysis. Its strong performance supports improved glaucoma-related structural assessment and has potential for clinical application.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of resident performed surgeries in complex cataract cases and comparative analysis with staff surgeons: a review of 1500 consecutive cases.","authors":"Gozde Derin Sengun, Ebubekir Durmus, Veysel Aykut, Halit Oguz, Fehim Esen","doi":"10.1007/s10792-026-04094-8","DOIUrl":"https://doi.org/10.1007/s10792-026-04094-8","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the intraoperative complication rates and incidence of postoperative day 1 (POD1) intraocular pressure (IOP) elevation in primary phacoemulsification cataract surgery performed by residents and staff surgeons in a teaching hospital and determine the risk factors associated with posterior capsule tear (PCT) and POD1 IOP elevation.</p><p><strong>Methods: </strong>This retrospective study included all cases of primary phacoemulsification in patients aged 18 years or older, performed by residents and staff surgeons from May 27, 2022, to May 31, 2023 in a tertiary eyecare center in Turkey. There were no exclusion criteria. Data collected included primary surgeon, level of experience, preoperative status of cases, intraoperative complications, other operative details and POD1 IOP measurements.</p><p><strong>Results: </strong>A total of 1500 surgeries were included; 68.8% were performed by residents. Overall intraoperative complication rates were similar in groups in simple and complex cases. There was no statistically significant difference in PCT rates between groups in simple (2.4% and 1.9%, p = 0.800) and complex cases (3.7% and 5.1%, p = 0.455). Rate of POD1 IOP elevation above 25 mm Hg was also similar in groups (22.7% and 22.6%, p = 0.903). Pseudoexfoliation + small pupil and special cataracts were significant risk factors for PCT among residents (p = 0.048 and p = 0.033, respectively). Pseudoexfoliation + small pupil, glaucoma or ocular hypertension and uveitis were significant risk factors for POD1 IOP elevation.</p><p><strong>Conclusion: </strong>Overall intraoperative complication and PCT rates were comparable between residents and staff surgeons in both simple and complex cases. Resident involvement was not a risk factor for POD1 IOP elevation.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute dacryocystitis: Microbiological profiles from an infectious diseases perspective.","authors":"Fatma Merve Koçak, Fatma Poslu Karademir","doi":"10.1007/s10792-026-04093-9","DOIUrl":"https://doi.org/10.1007/s10792-026-04093-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the microorganisms isolated, antimicrobial resistance patterns, clinical profiles, and therapeutic approaches in adult acute dacryocystitis cases requiring multidisciplinary management, and to present epidemiological data from Turkey.</p><p><strong>Methods: </strong>We retrospectively analyzed adult patients referred from a tertiary ophthalmology hospital to the infectious diseases (ID) specialist between January 2022 and April 2025. Clinical and microbiological data were obtained from electronic medical records. Pathogen identification and susceptibility testing were performed using routine microbiological methods, and the results were interpreted according to applicable standard criteria.</p><p><strong>Results: </strong>Sixty-eight patients were included (mean age: 54.9 years; 79.4% female). Of the 68 included patients, 49 underwent microbiological sampling when indicated and sufficient material was available; 38 (77.6%) had positive cultures, yielding 49 isolates. Staphylococcus aureus (n = 12) was the most frequent isolate. Pseudomonas aeruginosa and Enterobacteriaceae were the leading Gram-negative pathogens. All tested Gram-positive isolates were susceptible to vancomycin. Susceptibility to other antibiotics varied across pathogen groups. All fungal isolates were Candida species. Prior antibiotic exposure was not associated with lower culture positivity in this sample.</p><p><strong>Conclusion: </strong>In adult acute dacryocystitis, culture-based therapy is essential, particularly for complex or nonresponsive cases. This study presents local epidemiological data and may help guide empirical therapy and support individualized antimicrobial management.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Residual refraction after myopic implantable collamer lens implantation: clinical data vs optical models.","authors":"Adam Oleszko, Maria Muzyka-Woźniak, Malwina Terlecka","doi":"10.1007/s10792-026-04096-6","DOIUrl":"10.1007/s10792-026-04096-6","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the predictive accuracy of four optical modelling scenarios for postoperative refraction after myopic Implantable Collamer Lens (ICL) implantation using patient-specific clinical biometry and to validate the results against clinical postoperative refraction and vault data.</p><p><strong>Methods: </strong>This retrospective study analysed 215 eyes following myopic ICL implantation. Four optical vergence models were implemented using patient-specific preoperative biometry and measured postoperative vault. The scenarios differed in their treatment of corneal and phakic intraocular lens (pIOL) thickness: (A) thick cornea and thick pIOL; (B) thin cornea and thick pIOL; (C) thick cornea and thin pIOL; (D) thin cornea and thin pIOL. Postoperative spherical equivalent refraction was defined by objective autorefraction, with a sensitivity analysis for the subjective refraction in a subset of eyes. Prediction accuracy was assessed using mean error, mean absolute error, refractive accuracy thresholds, and Bland-Altman analysis. Two-dimensional dispersion was evaluated using standard distance deviation and standard deviational ellipses (SDE). Ellipse-aligned variance was compared using Brown-Forsythe tests with Bonferroni correction. The prediction accuracy of all scenarios were contrasted against the standard.</p><p><strong>Results: </strong>Scenarios assuming a centrally thick pIOL (A and B) systematically overestimated postoperative refraction, with biases exceeding + 1.0 D and wide limits of agreement (> ± 3.0 D). Thin-pIOL models demonstrated substantially improved agreement. Scenario C showed the lowest bias (0.30 ± 0.48 D), narrowest limits of agreement (- 0.62-1.21 D), smallest SDE area, and significantly reduced variance along both ellipse-aligned axes compared with Scenarios A and B (p < 0.001). No significant dispersion difference was observed between Scenarios C and D. Scenario C achieved prediction accuracy that was very close to that of the manufacturer's calculation algorithm.</p><p><strong>Conclusion: </strong>For myopic ICLs with central thinning and a central aperture, optical models assuming a thin pIOL provide postoperative refractive prediction. Model selection should prioritize optical relevance along the visual axis rather than anatomical complexity.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13149594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of corneal topography maps of a swept-source OCT biometer and a Scheimpflug device.","authors":"Michael Müller, Eva Hemkeppler, Myriam Böhm, Tyll Jandewerth, Christoph Lwowski, Thomas Kohnen","doi":"10.1007/s10792-026-04088-6","DOIUrl":"10.1007/s10792-026-04088-6","url":null,"abstract":"<p><strong>Purpose: </strong>Rating of central corneal topography of a swept-source OCT biometer (IOL Master 700) and tomographic maps from a Scheimpflug device (Pentacam AXL) by different experienced professionals regarding irregularities to support decisions on implanting premium intraocular lenses (IOLs).</p><p><strong>Methods: </strong>In this prospective study healthy eyes (H), irregular corneas (I) and eyes with previous corneal refractive surgery (P) were randomly selected. Five observers with different experience in corneal map evaluation compared the corneal topography maps of both devices individually. They answered a questionnaire for each picture and eye and the matched pictures. The questionnaire included the similarity in regularity of the cornea, the classification of the pictures regarding the included patient groups and the decision of premium IOL implantation.</p><p><strong>Results: </strong>The study included 25 eyes per group. The correct category (H, I or P) was reported in 52% to 70% of individual cases. Except one observer (p < 0.001) there were no significant difference between the two devices. Most observers rated irregular corneas significantly different than healthy or post refractive surgery eyes (p < 0.001). There were significant inter-observer agreements among the three observers for rating implantation premium IOLs 0.137 to 0.374 (p < 0.05) and rating the correct category 0.435 (p < 0.001).</p><p><strong>Conclusions: </strong>Irregular corneas were rated as significantly different to healthy or post refractive surgery eyes. Most observers rated the images of the swept-source OCT biometer and the Scheimpflug device equally. Regarding the selection of premium IOL experienced colleagues are preferable.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13149648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and multimodal imaging features of ocular syphilis with posterior segment involvement: a 10-case series.","authors":"Lai Wei, Shuang Wei, Zhiyong Wang","doi":"10.1007/s10792-026-04095-7","DOIUrl":"https://doi.org/10.1007/s10792-026-04095-7","url":null,"abstract":"<p><strong>Background: </strong>Ocular syphilis masquerades as posterior uveitis, causing delayed diagnosis. We delineated phenotypes, imaging and outcomes in treatment-naïve disease.</p><p><strong>Methods: </strong>A retrospective, observational case series was conducted on 10 consecutive patients (15 eyes; 6 females, 4 males; mean age 48.3 ± 12.1 years) diagnosed with syphilitic posterior uveitis between January 2013 and December 2024. All patients underwent comprehensive ophthalmic evaluation, serologic confirmation (positive Treponema pallidum particle agglutination and rapid plasma reagin), and multimodal imaging assessment including color fundus photography, fundus fluorescein angiography (FFA), and spectral-domain optical coherence tomography (SD-OCT). The primary outcome was the change in best-corrected visual acuity (BCVA, logMAR) after standard intravenous penicillin G therapy, analyzed using the Wilcoxon signed-rank test.</p><p><strong>Results: </strong>(1) Phenotype distribution: ASPPC was the most prevalent posterior-segment lesion (8/15 eyes, 53.3%), followed by optic perineuritis/papillitis (5 eyes, 33.3%) and retinal vasculitis (2 eyes, 13.3%). (2) Multimodal imaging features: SD-OCT in ASPPC consistently showed outer retinal disruption and ellipsoid zone loss, while FFA revealed characteristic early hypofluorescence with late speckled hyperfluorescence and leakage; optic perineuritis showed early disc hyperfluorescence with marked late-phase leakage; and retinal vasculitis demonstrated arterial wall staining with peripheral non-perfusion. (3) Visual outcomes: Following treatment, 14 eyes (93.3%) showed visual improvement, with median BCVA improving from 0.40 to 0.00 logMAR (P < 0.001). The initial misdiagnosis rate was 60% (6/10).</p><p><strong>Conclusions: </strong>In patients presenting with ocular syphilis as the initial manifestation, ASPPC is the most common posterior segment lesion. Multimodal imaging provides critical diagnostic clues. Despite frequent initial misdiagnosis, prompt penicillin therapy yields favorable visual outcomes. Routine syphilis serology screening is strongly recommended for any patient with unexplained posterior uveitis or optic neuropathy.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Switch to faricimab in various retinal diseases: real-world data.","authors":"Eitan Kaplan, Ori Segal, Elad Moisseiev, GIlad Allon","doi":"10.1007/s10792-026-04092-w","DOIUrl":"https://doi.org/10.1007/s10792-026-04092-w","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of faricimab in various retinal conditions in previously treated patients.</p><p><strong>Methods: </strong>This study included patients who received at least three faricimab injections at a large medical center between April 2023 and October 2024, all of whom were not naive to treatment.</p><p><strong>Results: </strong>A total of 242 eyes from 219 patients were included in the analysis. The diagnoses were: 139 eyes with neovascular age-related macular degeneration (NVAMD), 63 eyes with diabetic macular edema (DME), 24 eyes with polypoidal choroidal vasculopathy (PCV), 5 eyes with choroidal neovascularization (CNV) secondary to central serous retinopathy (CSR), 5 eyes with branch retinal vein occlusion (BRVO) accompanied by cystoid macular edema (CME), 3 eyes with central retinal vein occlusion (CRVO) with CME, and 3 eyes with myopic CNV. Patients had previously received intravitreal injections of medications including bevacizumab, ranibizumab, aflibercept 2 mg, brolucizumab, triamcinolone, and Ozurdex. Following treatment with faricimab, the proportion of eyes with no intraretinal or subretinal fluid increased across all retinal diseases. Additionally, the average central subfield thickness decreased, the interval between injections was extended, and average visual acuity improved in every retinal condition. The average height of the pigment epithelium detachment (PED) decreased in cases of NVAMD and PCV.</p><p><strong>Conclusions: </strong>Faricimab appears to be effective after the failure of other treatment options.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GPT-5-assisted versus expert surgeon refractive planning in smooth incision lenticule keratomileusis (SILK): comparative analysis and visual outcomes.","authors":"Pier Luigi Surico, Tsung-Hsien Tsai, David Hui-Kang Ma, Chao Kai Chang, Gabriele Gallo Afflitto, Hung-Yu Lin, Chih-Chin Pan, Antonio Perri, Antonio Di Zazzo, Paolo Lanzetta, Chi-Chin Sun","doi":"10.1007/s10792-026-04084-w","DOIUrl":"10.1007/s10792-026-04084-w","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the performance of GPT-5 in refractive surgery planning by comparing its recommendations with expert surgeons and reporting visual outcomes of surgeon-planned Smooth Incision Lenticule Keratomileusis (SILK) procedures.</p><p><strong>Methods: </strong>This retrospective, observational study included 134 eyes from 67 patients who underwent SILK procedure using the ELITA femtosecond laser platform from January 2024 to September 2025. GPT-5 generated refractive plans based on manifest and cycloplegic refraction, autorefractometry, visual acuity, keratometry, and pachymetry. These were compared with surgeon-derived values using paired t-tests and correlation analysis. Preoperative and postoperative (1- and 3-month) uncorrected and corrected distance visual acuity (UDVA, CDVA), mean keratometry (Km), and thinnest corneal point were analyzed. Axis concordance was quantified as the absolute angular deviation (Δ Axis) between AI- and surgeon-planned astigmatism axes.</p><p><strong>Results: </strong>AI-generated spherical corrections were more conservative than surgeons' (- 4.29 ± 2.42 D vs. - 4.70 ± 1.98 D; p = 0.0025), whereas cylindrical power did not differ significantly (p = 0.9241). The mean Δ Axis was 61.9° ± 50.1°, indicating substantial misalignment. UDVA improved from 0.74 ± 0.36 logMAR preoperatively to - 0.06 ± 0.07 logMAR at 3 months (p < 0.0001), and postoperative UDVA did not differ significantly from preoperative CDVA, confirming excellent visual recovery.</p><p><strong>Conclusions: </strong>GPT-5 generated refractive plans that were partially consistent with expert surgeon decisions but lacked the clinical precision required for clinical implementation. In contrast, surgeon-planned SILK procedures achieved excellent visual acuity, corneal stability, and refractive predictability, reinforcing the safety and efficacy of Kerato Lenticule Extraction (KLEx) in real-world clinical practice.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy and Safety of Recombinant Human Nerve Growth Factor (rhNGF) in Patients With Dry Eye Disease: A Systematic Review and Meta-analysis.","authors":"Mohammed F Qutub, Talal S Alajmi, Ahmed N Alnabihi, Anas Alamoudi, Salma H Almarwani, Suzan E Ageel, Baraa S Tabbakh, Lama N Alghamdi","doi":"10.1007/s10792-026-04086-8","DOIUrl":"https://doi.org/10.1007/s10792-026-04086-8","url":null,"abstract":"<p><strong>Background: </strong>Dry eye disease (DED) is a multifactorial condition affecting the ocular surface. Recombinant human nerve growth factor (rhNGF) has emerged as a potential new treatment for neurosensory dysfunction. The aim of this study is to evaluate the efficacy and safety of rhNGF in patients with DED.</p><p><strong>Methods: </strong>A comprehensive search of six online databases-Medline, CENTRAL, Web of Science, Ovid Medline, ClinicalTrials.gov, and Google Scholar-was conducted to identify randomized controlled trials (RCTs) evaluating the efficacy and safety of rhNGF in patients with dry eye disease, focusing on outcomes such as tear production, ocular surface integrity, and adverse events.</p><p><strong>Results: </strong>The results demonstrated that rhNGF significantly improved tear production compared with placebo, as measured by the Schirmer test (MD = 3.84; 95% CI: 2.17-5.51; P < 0.00001; I² = 8%). No significant differences were observed in corneal and conjunctival staining (MD = -0.69; 95% CI: -1.62 to 0.25; P = 0.15; I² = 0%) or tear breakup time (TBUT) (MD = 0.18; 95% CI: -1.08 to 1.45; P = 0.78; I² = 80%). Non-severe adverse events were more frequent with rhNGF, while serious adverse events were similar between groups. Non-severe adverse events were more frequent in the rhNGF group, while the incidence of serious adverse events was comparable to that of the placebo group.</p><p><strong>Conclusion: </strong>rhNGF shows promise for improving tear production in patients with dry eye disease, as demonstrated by significant improvement in Schirmer test results. However, evidence for broader clinical efficacy remains limited, with other outcomes showing non-significant or heterogeneous findings. Current data are based on a small number of trials, indicating the need for larger, well-designed studies to clarify the therapeutic role and safety profile of rhNGF in dry eye disease.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative residual refractive astigmatism analysis in cylinder correction with toric IOL in patients with different degrees of astigmatism using AS-OCT and total keratometry.","authors":"Alessandro de Paula, Lucrezia Leucci, Andrea Corsi","doi":"10.1007/s10792-026-04085-9","DOIUrl":"https://doi.org/10.1007/s10792-026-04085-9","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the refractive outcomes in patients with different degrees of astigmatism undergoing cataract surgery with toric monofocal IOL implantation.</p><p><strong>Methods: </strong>A consecutive series of patients that underwent cataract surgery and Toric IOL implantation was reviewed. The preoperative evaluation of anterior and posterior keratometry, corneal topo/tomography was performed with AS-OCT Casia 2. Basing on real cylinder, the patients were divided in three groups. Group 1: total corneal astigmatism ≤ 1D, group 2: total corneal astigmatism between 1 and 1.5 D, group 3: total corneal astigmatism ≥ 1.5D. The residual post-operative refractive astigmatism and the percentage of astigmatic correction were evaluated one months after the surgery. Vector astigmatism analysis was performed applying the Alpins method.</p><p><strong>Results: </strong>100 eyes of 100 patients were enrolled. The mean post-operative refractive astigmatism (in absolute values) was 0.23 ± 0.28 D; 0.16 ± 0.27 D and 0.48 ± 0.44 D in group 1, 2 and 3 respectively. The best percentage of astigmatic correction was found in group 2 (88.05 ± 20.11%) with a significant difference with group 1 and 3. The average AE was 5.68 ± 8.33° in group 1, 2.2 ± 4.13° in group 2 and 3.97 ± 4.89° in group 3. The differences were significant in particularly between the second and the third group and less between the first and the second group. The best DV and IOS were found in group 2.</p><p><strong>Conclusion: </strong>Toric IOL was successfully applied in any amount of astigmatism and that the best refractive results were achieved in mild astigmatism.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}