International Ophthalmology最新文献

Visual field outcomes after cataract surgery with or without microinvasive glaucoma surgery in open-angle glaucoma: a systematic review and meta-analysis of RCTs reporting visual field results. 开角型青光眼患者白内障手术伴或不伴微创青光眼手术后的视野结果：报告视野结果的随机对照试验的系统回顾和荟萃分析。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-28 DOI: 10.1007/s10792-025-03579-2

Hajar Nasir Tukur, Orlando Daniel Quintanar-Haro, Okan Toygar

{"title":"Visual field outcomes after cataract surgery with or without microinvasive glaucoma surgery in open-angle glaucoma: a systematic review and meta-analysis of RCTs reporting visual field results.","authors":"Hajar Nasir Tukur, Orlando Daniel Quintanar-Haro, Okan Toygar","doi":"10.1007/s10792-025-03579-2","DOIUrl":"https://doi.org/10.1007/s10792-025-03579-2","url":null,"abstract":"Purpose: To compare the benefits of combining microinvasive glaucoma surgery (MIGS) with cataract surgery (CS) for visual field (VF) preservation in patients with primary open-angle glaucoma (POAG) and coexisting cataracts.Methods: A systematic review and meta-analysis were conducted on randomised controlled trials (RCTs) comparing MIGS + CS to CS alone in POAG patients with cataracts that specifically reported visual field outcomes. Studies included were required to report VF outcomes with a follow-up of at least 12 months. Subanalysis focused on studies with 24-month follow-up durations, and consistent device used.Results: Three RCTs encompassing 857 eyes were included, with 523 eyes in the MIGS + CS group and 334 in the CS group. MIGS + CS was associated with a statistically significant reduced rate of VF deterioration in Mean Deviation (MD) at the 24-month follow-up compared to CS alone (SMD 0.29; p = 0.007), and a significant difference between groups in the rate of VF progression (MD 0.23 decibels (dB)/year; p = 0.00001). However, there was no difference in IOP reduction (MD -0.46 mmHg; p = 0.40). The MIGS + CS group showed a significant reduction in medication use (MD -0.36 medications; p < 0.00001).Conclusion: Among the MIGS devices studied (iStent and Hydrus), combining them with cataract surgery provided VF benefits in terms of rate of deterioration and decline, and reduced medication dependence. Standardised follow-up and reporting practices are essential for evaluating MIGS's role in glaucoma management.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"215"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance of a novel multimodal large language model in ınterpreting meibomian glands quantitatively and qualitatively. 一种新型多模态大型语言模型在ınterpreting睑板腺中的定量和定性表现。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-28 DOI: 10.1007/s10792-025-03587-2

Pelin Kiyat, Melis Palamar

{"title":"Performance of a novel multimodal large language model in ınterpreting meibomian glands quantitatively and qualitatively.","authors":"Pelin Kiyat, Melis Palamar","doi":"10.1007/s10792-025-03587-2","DOIUrl":"https://doi.org/10.1007/s10792-025-03587-2","url":null,"abstract":"Purpose: To evaluate the performance of a multimodal large language model (LLM), Claude 3.5 Sonnet, in interpreting meibography images for Meibomian gland dropout grading and morphological abnormality detection.Methods: A total of 228 meibography images were analyzed by the same researcher and an assessment was performed in terms of gland drop out ratio and morphological abnormalities. Meibomian gland loss was graded from 0 (no loss) to 3 (> 2/3 loss of total gland area). One-hundred and sixty images, comprising 40 images per grade, were included. Claude 3.5 Sonnet, a multimodel LLM, developed by Anthropic (California, United States) was utilized to investigate its performance in evaluating meibography images.Results: Claude 3.5 Sonnet showed high performance in grading Meibomian gland dropout, correctly scoring 97.5%, 92.5%, 95%, and 85% of images in Grades 0, 1, 2, and 3, respectively. In addition, Claude 3.5 Sonnet showed remarkable performance in detecting morphological abnormalities, including heterogeneous lumen diameters, lumen tortuosity, shortened lumen length, and hyperreflective gland residues. The model detected all of the 48 manually identified morphological abnormalities accurately. In 12 images, initially classified as morphologically normal by the manual assessment, the model reported additional subtle abnormalities.Conclusion: Claude 3.5 Sonnet showed promising results in interpreting meibography images, detecting morphological abnormalities and discriminating normal Meibomian glands from abnormal. Claude 3.5 Sonnet might be useful in serving as a complementary educational tool in ophthalmology clinics. The model's ability to perform detailed morphological evaluations and respond to further questions provides a tailored learning experience for young ophthalmic clinicians.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"216"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The spatulated glass rod: low-tech instrument for high-impact ophthalmic diagnosis and treatment. 匙形玻璃棒：低技术含量的高影响眼科诊断和治疗仪器。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-28 DOI: 10.1007/s10792-025-03569-4

Michelle Bai, Michele Y Fu, Grace A Borchert, Natalie S Lee, Amitouj S Sidhu, Ivy Jiang, Peter J Tweedie, Susan C Gaden, Ashish Agar, Ian C Francis

{"title":"The spatulated glass rod: low-tech instrument for high-impact ophthalmic diagnosis and treatment.","authors":"Michelle Bai, Michele Y Fu, Grace A Borchert, Natalie S Lee, Amitouj S Sidhu, Ivy Jiang, Peter J Tweedie, Susan C Gaden, Ashish Agar, Ian C Francis","doi":"10.1007/s10792-025-03569-4","DOIUrl":"https://doi.org/10.1007/s10792-025-03569-4","url":null,"abstract":"Purpose: To describe the utility of the Spatulated Glass Rod (SGR), which is a low-tech but diagnostically and therapeutically high-impact instrument used in Ophthalmology for at least twelve clinical and surgical tasks.Methods: A literature review was conducted, examining the use of the glass rod both historically and in its applications in Ophthalmology. The MEDLINE database was searched for the terms 'double eversion of upper eyelid', 'retained contact lens\", 'spatulated glass rod' and 'spatulated glass rod in ophthalmology'.Results: Detailed descriptions are provided of the specific use of the SGR in twelve disorders, but particularly in the emergent management of acute angle closure using corneal indentation, and inspection of the upper fornix for elusive foreign bodies by double eversion of the upper lid. The authors' Head Stabilisation Technique (HST) is also described as this facilitates safe head stabilisation by a novice assistant during the real-time application of the SGR.Conclusion: The SGR has proven to be an extremely useful instrument, with at least twelve different applications in both diagnostic and therapeutic contexts in Ophthalmology. Safe and effective use of the SGR is supported by the HST.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"214"},"PeriodicalIF":1.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Childhood asthma, inhaled corticosteroid exposure, and risk of cataract in adulthood: a register-based study. 儿童哮喘、吸入皮质类固醇暴露和成年后白内障风险：一项基于登记的研究。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-27 DOI: 10.1007/s10792-025-03586-3

Osman Savran, Daniella Bach-Holm, Jens Christian Nørregaard, Line Kessel, Charlotte Suppli Ulrik

{"title":"Childhood asthma, inhaled corticosteroid exposure, and risk of cataract in adulthood: a register-based study.","authors":"Osman Savran, Daniella Bach-Holm, Jens Christian Nørregaard, Line Kessel, Charlotte Suppli Ulrik","doi":"10.1007/s10792-025-03586-3","DOIUrl":"https://doi.org/10.1007/s10792-025-03586-3","url":null,"abstract":"Background: Cataract is the leading cause of blindness worldwide, with corticosteroid treatment being a known risk factor. The long-term impact of childhood asthma and, particularly, inhaled corticosteroid (ICS) use in adulthood on cataract development remains unclear.Methods: This register-based study investigated the prevalence and risk of cataract in Danish adults diagnosed with childhood asthma who, between 1950 and 1979, spent four months at an asthma care facility in Kongsberg, Norway. Follow-up was conducted in 2021 using Danish national health registries (2006-2018). These individuals were compared to an age- and sex-matched control group with no history of obstructive airway disease. Participants were stratified by ICS treatment duration and daily dose. Conditional logistic regression was used to assess associations.Results: The study included 1394 adults with childhood asthma and 1394 controls (mean age 63 years; 43% female). Cataract prevalence was 6.1% in the childhood asthma cohort versus 4.3% in controls (p = 0.03). Compared to controls, individuals with childhood asthma had increased odds of cataract (OR 1.47, 95% CI 1.04-2.08, p = 0.03). Among those treated with ICS, the odds were higher (OR 1.75, 95% CI 1.19-2.57, p < 0.01), with the risk increasing in proportion to ICS dose and treatment duration. No significant difference in cataract risk was found between individuals with childhood asthma who did not receive ICS and controls (OR 1.12, 95% CI 0.69-1.79, p = 0.65).Conclusions: Childhood asthma diagnosis alone was not associated with increased cataract risk. However, among those treated with ICS in adulthood, there was a significantly elevated risk, which increased with higher doses and longer treatment durations.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"211"},"PeriodicalIF":1.4,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The NYEE-Orbis oculoplastic surgery online curriculum: global access to oculoplastics education. nye - orbis眼科整形外科在线课程：全球获得眼科教育。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-27 DOI: 10.1007/s10792-025-03529-y

Ha Min Kim, Jason J Jo, Jennifer L Patnaik, Helen Liu, Jackson Scharf, David Hunter Cherwek, Daniel Neely, Shailesh Gaurav, Harsha S Reddy

{"title":"The NYEE-Orbis oculoplastic surgery online curriculum: global access to oculoplastics education.","authors":"Ha Min Kim, Jason J Jo, Jennifer L Patnaik, Helen Liu, Jackson Scharf, David Hunter Cherwek, Daniel Neely, Shailesh Gaurav, Harsha S Reddy","doi":"10.1007/s10792-025-03529-y","DOIUrl":"https://doi.org/10.1007/s10792-025-03529-y","url":null,"abstract":"Purpose: This study investigates the global reach of two novel, interactive, online, and free courses entitled \"Basics of Oculoplastic Surgery\" (BOS) and \"Intermediate Oculoplastic Surgery\" (IOS) and assesses how effectively they enhanced knowledge of oculoplastics conditions and procedures.Methods: The two courses were developed and uploaded online via the e-learning platform of Orbis International, Cybersight. Pre- and post-course surveys were administered to all enrollees to assess for demographics, course progress, baseline experience, and learning outcomes. Pre- and post-course survey data were compared using chi-square tests for yes or no questions and student t-tests for Likert scale items for each course separately.Results: As of August 2024, the BOS course had 2776 enrollees from 150 countries, while the IOS course had 1722 enrollees from 139 countries. The most frequent users of both courses were ophthalmologists, residents, medical students, nurses, and optometrists. For the BOS and IOS courses, 518 (18.7%) and 188 (10.9%) enrollees completed the courses, respectively. Pre- and post-course survey participants reported significant improvements in understanding oculoplastic procedures and conditions in the two courses (p < 0.0001 for all). Qualitative feedback for the BOS and IOS were overwhelmingly positive (95.2% and 96.9%, respectively).Conclusion: Both the BOS and IOS courses effectively reached a global audience and improved self-reported comfort and knowledge in oculoplastic procedures and conditions. These courses demonstrate promise as accessible and useful oculoplastic surgery education tools to international audiences of various backgrounds.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"212"},"PeriodicalIF":1.4,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracorneal connective tissue alterations in keratoconus: ultrasonographic evaluation of tendon, plantar fascia, and cartilage. 圆锥角的角膜外结缔组织改变：跟腱、足底筋膜和软骨的超声评估。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-27 DOI: 10.1007/s10792-025-03588-1

Alper Uysal, Çağrı İlhan, Merve Erdem Uysal, Tuğçe Gül, Murat Güzel

{"title":"Extracorneal connective tissue alterations in keratoconus: ultrasonographic evaluation of tendon, plantar fascia, and cartilage.","authors":"Alper Uysal, Çağrı İlhan, Merve Erdem Uysal, Tuğçe Gül, Murat Güzel","doi":"10.1007/s10792-025-03588-1","DOIUrl":"https://doi.org/10.1007/s10792-025-03588-1","url":null,"abstract":"Purpose: Structures such as the cornea, Achilles tendon (AT), plantar fascia (PF), and cartilage share the common feature of containing collagen and being associated with collagenous tissue disorders. However, the relationship between keratoconus and AT and PF thicknesses has not been investigated before. The importance of this study lies in the potential to identify a link between keratoconus and conditions such as Achilles tendinitis, plantar fasciitis, or osteoarthritis.Methods: This prospective, comparative study includes 33 keratoconus patients and 33 age- and gender-matched controls. AT, PF, talar cartilage (TC), and distal femoral cartilage (DFC) thicknesses were obtained by ultrasound (US). US parameters of the study and control groups were compared.Results: The mean AT and PF thicknesses were significantly higher in the study group (p = 0.002 and p < 0.001, respectively). On the other hand, the mean lateral femoral condyle (LFC), medial femoral condyle (MFC), DFC, and TC thicknesses were significantly lower in the study group (p < 0.001, for all). There was a significant correlation between corneal thickness and AT thickness (r = - 0.482, p = 0.005) and between corneal thickness and intercondylar area (IA) thickness (r = 0.367, p = 0.036). No significant relationship was found between maximum keratometry and US parameters, and BCV index and US parameters (p > 0.05, for all).Conclusion: This study clearly demonstrates that patients with keratoconus have significant PF, tendon and cartilage thickness abnormalities. Keratoconus patients may have a tendency to develop conditions such as Achilles tendinitis, plantar fasciitis, or osteoarthritis.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"213"},"PeriodicalIF":1.4,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Awareness of Charles Bonnet syndrome among ophthalmologists: a survey study. 眼科医生对查尔斯·邦纳综合征的认识：一项调查研究。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-26 DOI: 10.1007/s10792-025-03575-6

Gamze Ucan Gunduz, Ozgur Yalcinbayir, Oner Gelisken

{"title":"Awareness of Charles Bonnet syndrome among ophthalmologists: a survey study.","authors":"Gamze Ucan Gunduz, Ozgur Yalcinbayir, Oner Gelisken","doi":"10.1007/s10792-025-03575-6","DOIUrl":"https://doi.org/10.1007/s10792-025-03575-6","url":null,"abstract":"Purpose: Charles Bonnet Syndrome (CBS) is a condition characterized by complex visual hallucinations in individuals with significant visual impairment. Despite its prevalence, CBS remains under-recognized, leading to delayed diagnoses and unnecessary distress for patients and their families. Awareness among ophthalmologists is critical for early identification and management. This study aims to evaluate the awareness and understanding of CBS among ophthalmologists and identify gaps in knowledge, diagnosis, and management practices.Methods: A cross-sectional survey of 322 ophthalmologists was conducted using the SurveyMonkey® platform. The survey assessed demographic characteristics, awareness, and CBS diagnosis and management approaches. Statistical analyses included the Chi-square and Bonferroni methods.Results: While 63.9% of ophthalmologists surveyed were aware of CBS, only 21% of them were able to accurately answer all four questions (questions 8-11) regarding the definition of CBS, the vision levels at which it can be observed, the types of hallucinations it involves, and the ocular diseases in which it may occur. In addition, 66% of the participants had not encountered a CBS case in the past year. Awareness was significantly lower among those with ≤ 5 years of experience (33.3%) compared to those with ≥ 6 years (p < 0.001). General ophthalmologists demonstrated lower awareness (53.2%) than specialists in posterior segment disorders and uveitis (77.2%). Only 16.1% routinely enquired about symptoms of CBS. Most ophthalmologists prefer to refer patients to other specialties rather than manage cases themselves.Conclusions: Ophthalmologists' limited awareness of CBS and their failure to question symptoms in patients with low vision may lead to underdiagnosis of these patients. Comprehensive education programs, awareness campaigns, and clinical guidelines are necessary to improve outcomes for patients with CBS.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"207"},"PeriodicalIF":1.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global research trends on endoplasmic reticulum stress in retinal diseases from 2000 to 2024. 2000 - 2024年视网膜疾病内质网应激的全球研究趋势。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-26 DOI: 10.1007/s10792-025-03584-5

Weiwen Hu, Yahan Tu, Jian Tan, Yeting Lin, Yicang Wang, Qiong Zhou

{"title":"Global research trends on endoplasmic reticulum stress in retinal diseases from 2000 to 2024.","authors":"Weiwen Hu, Yahan Tu, Jian Tan, Yeting Lin, Yicang Wang, Qiong Zhou","doi":"10.1007/s10792-025-03584-5","DOIUrl":"https://doi.org/10.1007/s10792-025-03584-5","url":null,"abstract":"Purpose: To comprehensively explore global research trends on endoplasmic reticulum stress (ERS) in retinal diseases over the past 24 years.Methods: An analysis of 917 publications from the Web of Science Core Collection, spanning from 1 January 2000 to 15 April 2024, was conducted to explore ERS research in retinal diseases. Bibliometric and visualisation software was employed to identify key contributors and research trends.Results: Hideaki Hara and Sarah X. Zhang were identified as the most published and most cited authors, respectively. The United States led in both publications and citations. Sun Yat-sen University ranked highest in publications, while the University of Oklahoma received the most citations. Investigative Ophthalmology & Visual Science was the leading journal in both publications and citations. A total of 108 of the 1385 author keywords, each occurring five or more times, clustered into four major themes: retinal photoreceptor degeneration, glaucoma and optic nerve damage, diabetic retinopathy and age-related macular degeneration. Keywords such as \"in vivo\", \"dominant retinitis pigmentosa\", \"endothelial growth factor\", \"molecular\", and \"quality control\" displayed the strongest citation bursts. ERS research (2000 ~ 2024) has evolved from retinal neuroprotection to include specific cell types and diseases, explored signalling pathways and therapeutic mechanisms, and more recently has focused on molecular insights and gene therapy applications.Conclusion: This bibliometric analysis highlighted significant growth in publications on ERS in retinal diseases, reflecting an increasing scholarly focus. ERS represents a potential target for exploring pathological changes in retinal neuro-microvascular and related disorders, warranting further investigation.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"210"},"PeriodicalIF":1.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic performance of color vision tests for color vision deficiency: a network meta-analysis on comparisons of multiple color vision tests. 色觉缺陷的色觉测试诊断表现：多项色觉测试比较的网络元分析。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-26 DOI: 10.1007/s10792-025-03559-6

Ning Zhang, Jian Yang, Mosheng Hu, Ziye Liu

{"title":"Diagnostic performance of color vision tests for color vision deficiency: a network meta-analysis on comparisons of multiple color vision tests.","authors":"Ning Zhang, Jian Yang, Mosheng Hu, Ziye Liu","doi":"10.1007/s10792-025-03559-6","DOIUrl":"10.1007/s10792-025-03559-6","url":null,"abstract":"Purpose: This network meta-analysis (NMA) was done to compare the performance of color vision tests in the detection of individuals with color vision deficiency (CVD).Methods: Medline (via PubMed), Embase, and Web of Science were comprehensively searched from inception of the databases to 17 January, 2023. Conventional meta-analysis of diagnostic indicators was performed. The superiority of a diagnostic approach was depicted using the Superiority (S) Index.Results: Six studies were enrolled. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio, and area under the curve of summary receiver operating characteristic of the Ishihara tests were 0.89 (0.81, 0.94), 0.99 (0.96, 1.00), 110.8 (18.1, 677.0), 0.10 (0.05, 0.20), 1105 (112, 10,930), and 0.98 (0.96, 0.99). Waggoner Computerized Color Vision Test ranked the best performance in the detection of CVD, followed by CAD test, Ishihara test, Fletcher Lantern test, and HHR test as the rest second to the fifth most effective modalities.Conclusion: This NMA revealed that CAD test, Ishihara test, Fletcher Lantern test, and HHR test had favorable diagnostic validity in the detection of CVD.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"208"},"PeriodicalIF":1.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optical coherence tomography biomarkers and visual functions in tuberculous meningitis: an observational study. 结核性脑膜炎的光学相干断层扫描生物标志物和视觉功能：一项观察性研究。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-05-26 DOI: 10.1007/s10792-025-03594-3

Shweta Singh, Deepika Verma, Sanjiv Kumar Gupta, Pramod Kumar

{"title":"Optical coherence tomography biomarkers and visual functions in tuberculous meningitis: an observational study.","authors":"Shweta Singh, Deepika Verma, Sanjiv Kumar Gupta, Pramod Kumar","doi":"10.1007/s10792-025-03594-3","DOIUrl":"https://doi.org/10.1007/s10792-025-03594-3","url":null,"abstract":"Purpose: To evaluate changes in optical coherence tomography (OCT) parameters and visual function in Tuberculous Meningitis (TBM) patients during a short-term follow-up period. A prospective case-control observational study was performed at a Medical University from August 2020 to July 2021.Method: A study was conducted at a medical institute in Northern India, including 52 patients with TBM who presented within one month of systemic symptoms. Optical Coherence Tomography parameters, retinal nerve fiber layer (RNFL) thickness, central sub-foveal thickness (CST), cube average thickness (CAT), and visual function were evaluated at the time of presentation and after one month of follow-up period.Results: The study included 52 TBM patients, the mean age was 27 (51.9%) and 25 (48.1%) years, out of 52 patients, 24 (46.2%) were male, and 28 (53.8%) were female. OCT revealed significant thickening of the RNFL, mean of 108.7 μm in the right eye and 108.69 μm in the left eye after 1 month of diagnosis. No significant difference was found between macular parameters (CST, CAT) and visual functions.Conclusions: OCT biomarkers, particularly RNFL thickness, are significantly altered in TBM patients, indicating its potential as a sensitive marker for monitoring retinal changes. The macula appears to be spared in the early phase of TBM, and visual acuity remains relatively unaffected in the short-term follow-up.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"209"},"PeriodicalIF":1.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0