{"title":"羊膜移植治疗黄斑孔：解码最佳方法-镶嵌还是覆盖？","authors":"Yali Liu, Li Zhou, Zhouli Tan","doi":"10.1007/s10792-025-03761-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>No consensus has been reached on the treatment of refractory/recurrent macular holes (MHs), chronic MHs, or highly myopic MHs. Although amniotic membrane transplantation (AMT) has been extended from ocular surface surgery to MH treatment, the comparative advantages of inlay versus overlay application of human amniotic membrane (hAM), as well as the impact of different preparation and preservation methods, remain controversial.</p><p><strong>Methods: </strong>A systematic review of recent literature on AMT for MHs was conducted, categorizing applications and summarizing critical surgical considerations.</p><p><strong>Results: </strong>Current studies indicate: Inlay AMT is suitable for complex MHs, providing mechanical support, while overlay AMT promotes better healing. Preparation methods (e.g., freeze-dried vs. fresh amniotic membrane) may affect biological activity. Surgical approaches should be tailored based on MH type, disease duration, and individual patient factors.</p><p><strong>Conclusion: </strong>AMT offers a novel approach to MH treatment, but standardized patient selection criteria and surgical techniques require further refinement. This review provides valuable insights for clinicians in optimizing surgical strategies.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"408"},"PeriodicalIF":1.4000,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Amniotic membrane transplantation for macular holes: decoding the optimal approach-inlay or overlay?\",\"authors\":\"Yali Liu, Li Zhou, Zhouli Tan\",\"doi\":\"10.1007/s10792-025-03761-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>No consensus has been reached on the treatment of refractory/recurrent macular holes (MHs), chronic MHs, or highly myopic MHs. Although amniotic membrane transplantation (AMT) has been extended from ocular surface surgery to MH treatment, the comparative advantages of inlay versus overlay application of human amniotic membrane (hAM), as well as the impact of different preparation and preservation methods, remain controversial.</p><p><strong>Methods: </strong>A systematic review of recent literature on AMT for MHs was conducted, categorizing applications and summarizing critical surgical considerations.</p><p><strong>Results: </strong>Current studies indicate: Inlay AMT is suitable for complex MHs, providing mechanical support, while overlay AMT promotes better healing. Preparation methods (e.g., freeze-dried vs. fresh amniotic membrane) may affect biological activity. Surgical approaches should be tailored based on MH type, disease duration, and individual patient factors.</p><p><strong>Conclusion: </strong>AMT offers a novel approach to MH treatment, but standardized patient selection criteria and surgical techniques require further refinement. This review provides valuable insights for clinicians in optimizing surgical strategies.</p>\",\"PeriodicalId\":14473,\"journal\":{\"name\":\"International Ophthalmology\",\"volume\":\"45 1\",\"pages\":\"408\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s10792-025-03761-6\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10792-025-03761-6","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Amniotic membrane transplantation for macular holes: decoding the optimal approach-inlay or overlay?
Background: No consensus has been reached on the treatment of refractory/recurrent macular holes (MHs), chronic MHs, or highly myopic MHs. Although amniotic membrane transplantation (AMT) has been extended from ocular surface surgery to MH treatment, the comparative advantages of inlay versus overlay application of human amniotic membrane (hAM), as well as the impact of different preparation and preservation methods, remain controversial.
Methods: A systematic review of recent literature on AMT for MHs was conducted, categorizing applications and summarizing critical surgical considerations.
Results: Current studies indicate: Inlay AMT is suitable for complex MHs, providing mechanical support, while overlay AMT promotes better healing. Preparation methods (e.g., freeze-dried vs. fresh amniotic membrane) may affect biological activity. Surgical approaches should be tailored based on MH type, disease duration, and individual patient factors.
Conclusion: AMT offers a novel approach to MH treatment, but standardized patient selection criteria and surgical techniques require further refinement. This review provides valuable insights for clinicians in optimizing surgical strategies.
期刊介绍：
International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
