International Ophthalmology最新文献_第10页

Analysis of differences between keratometric astigmatism and total corneal astigmatism measured by IOLMaster 700. iolmaster700测量角膜屈光度散光与全角膜散光的差异分析。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-02-07 DOI: 10.1007/s10792-024-03394-1

Chunxia Yu, Xiaoling Fang, Jinhua Tao, Yiping Dong, Shenyu Ben, Yulan Wang

{"title":"Analysis of differences between keratometric astigmatism and total corneal astigmatism measured by IOLMaster 700.","authors":"Chunxia Yu, Xiaoling Fang, Jinhua Tao, Yiping Dong, Shenyu Ben, Yulan Wang","doi":"10.1007/s10792-024-03394-1","DOIUrl":"10.1007/s10792-024-03394-1","url":null,"abstract":"Purpose: To compare keratometric astigmatism (ΔK) and total corneal astigmatism (ΔTK) calculated by the IOLMaster 700 in cataract cases with regular corneal astigmatism ≥ 0.75 diopters (D).Methods: This study was a secondary analysis of a database of cataract patients who had undergone examination with IOLMaster 700 between May 2021 and March 2022 at Shanghai Eye Disease Prevention and Treatment Center. The Surgically Induced Astigmatism Calculator v2.1 was used to examine vector errors between ΔK and ΔTK. Subgroup analyses were performed based on ΔK axis, ΔK magnitude, age, gender, mean simulated keratometry (Km), and white-to-white corneal diameter (WTW).Results: In total, 580 eyes in 580 cases were included. The centroid values of ΔK and ΔTK were 0.28 D at 4° ± 1.55 D and 0.51 D at 4° ± 1.60 D, respectively. ΔTK (1.38 [1.02-1.85] D) was significantly larger than ΔK (1.25 [0.98-1.69] D) (P < 0.0001). The absolute value of the vector error between ΔK and ΔTK (|ΔTK - ΔK|) was 0.24 (0.18-0.31) D. Among groups categorized based on ΔK axis, the |ΔTK - ΔK| was markedly reduced in the with-the-rule (WTR) astigmatism group compared with other groups; ΔTK was starkly lower than ΔK in the WTR astigmatism group (P = 0.0006), while ΔTK was larger than ΔK in the against-the-rule (ATR) astigmatism (P < 0.0001). The |ΔTK - ΔK| increased with the magnitude of ΔK and with age. The difference between ΔK and ΔTK showed no correlations with gender, Km, and WTW (all P > 0.05).Conclusions: A significant difference between ΔK and ΔTK obtained by IOLMaster 700 was found in cataract cases with regular corneal astigmatism ≥ 0.75 D. Such a difference was markedly reduced in the WTR astigmatism group. In contrast, this difference increased with the magnitude of ΔK and age. Moreover, this difference was not associated with gender, Km, and WTW.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"66"},"PeriodicalIF":1.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of higher pain in possible open globe injury emergency medical services activations. 在可能的开放性损伤紧急医疗服务激活中较高疼痛的预测因素。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-31 DOI: 10.1007/s10792-025-03418-4

Hassaam S Choudhry, David Mothy, Aneesh Reddy, Aman M Patel, Skyler Peterson, Benjamin Fisher, Mohammad H Dastjerdi

{"title":"Predictors of higher pain in possible open globe injury emergency medical services activations.","authors":"Hassaam S Choudhry, David Mothy, Aneesh Reddy, Aman M Patel, Skyler Peterson, Benjamin Fisher, Mohammad H Dastjerdi","doi":"10.1007/s10792-025-03418-4","DOIUrl":"10.1007/s10792-025-03418-4","url":null,"abstract":"Purpose: To determine predictors of high pain in open globe injury (OGI) cases treated and transported by Emergency Medical Services.Methods: The National Emergency Medical Services Information System database was queried for activations of OGI between 2017 and 2021. Demographic, location, medication, and date and time information was collected. Cases were divided based on the intensity of maximum pain reported (low pain: below 5/10, high pain: above 5/10). Logistic regression was used to identify significant predictors of high maximum pain.Results: Of 53,589 cases of OGI, 20,766 reported high levels of pain. Females were more likely to report high pain than males (OR 1.24, CI 1.195-1.285). All age groups between 16 and 75 years old were more likely to report high pain than patients below 15, while all age groups above 75 were less likely. American Indians/Alaska Natives, Black, and Hispanic Americans were all more likely to report high pain than White Americans (American Indian, OR 1.249, CI 1.067-1.461; Black, OR 1.332, CI 1.277-1.390; Hispanic, OR 1.133, CI 1.064-1.207). OGI cases in the Midwest and South regions were less likely to report high pain than those in the West (Midwest, OR 0.868, CI 0.807-0.933; South, OR 0.800, CI 0.748-0.855). Compared to low pain patients, a greater percentage of high pain patients received opioid analgesia (10.04% vs. 0.44%).Conclusions: Demographic factors and location may contribute to higher pain in OGI patients. This information may prove useful in the management of OGI and may warrant further investigation into the nature of open globe trauma.Kindly check and confirm the inserted city is correct for affiliation 3.Correct.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"53"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11785623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diurnal rhythm-modulated transcriptome analysis of meibomian gland in hyperlipidemic mice using RNA sequencing. 利用RNA测序对高脂血症小鼠睑板腺的昼夜节律调节转录组进行分析。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-31 DOI: 10.1007/s10792-025-03431-7

Qing Zhang, Jinxing Su, Jing Chen, Sainan Wu, Xiaoxuan Qi, Min Chu, Shangquan Jiang, Kan He

{"title":"Diurnal rhythm-modulated transcriptome analysis of meibomian gland in hyperlipidemic mice using RNA sequencing.","authors":"Qing Zhang, Jinxing Su, Jing Chen, Sainan Wu, Xiaoxuan Qi, Min Chu, Shangquan Jiang, Kan He","doi":"10.1007/s10792-025-03431-7","DOIUrl":"https://doi.org/10.1007/s10792-025-03431-7","url":null,"abstract":"Aim: To explore the regulatory mechanism of meibomian gland (MG) in hyperlipidemic mice under a diurnal rhythm by transcriptomic analysis based on high-throughput sequencing.Methods: The mouse model of hyperlipidemia induced by four months of high-fat diet (HFD) feeding to a regular light-dark (LD) cycle for 2 weeks was used in this study. Phenotypic observation and RNA sequencing (RNA-seq) of MGs of the experimental mice were then performed to investigate transcriptional changes due to hyperlipidemia and the diurnal rhythm and their effects on meibomian gland dysfunction (MGD).Results: The expression levels of the identified dysregulated genes were then validated by qRT-PCR. Several significantly regulated genes and enriched pathways were identified as associated with MGD in hyperlipidemic mice under a diurnal rhythm; these genes included some core diurnal clock genes, e.g., Clock, Per2 and Per3. Phenotypic and histological analysis reveals abnormal morphology concomitantly with a modification of the transcriptional landscape of MG caused by HFD.Conclusion: Our findings provide us with a deeper understanding of the diurnal rhythm regulation of MG in hyperlipidemic mice altered by daily nutritional challenge.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"57"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparison of endothelial cell count, central corneal thickness and intraocular pressure in different ethnic groups in the Western Cape, South Africa. 南非西开普省不同种族人群内皮细胞计数、角膜中央厚度和眼压的比较

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-31 DOI: 10.1007/s10792-025-03426-4

Raquel Bhika, Moleen Zunza, Derrick Smit

{"title":"A comparison of endothelial cell count, central corneal thickness and intraocular pressure in different ethnic groups in the Western Cape, South Africa.","authors":"Raquel Bhika, Moleen Zunza, Derrick Smit","doi":"10.1007/s10792-025-03426-4","DOIUrl":"10.1007/s10792-025-03426-4","url":null,"abstract":"Purpose: To compare endothelial cell counts (ECC), central corneal thickness (CCT) and intraocular pressure (IOP) in different ethnic groups.Methods: Between January 2019 and December 2021, we enrolled 373 patients who self-identified as native African (116), ethnically diverse (157) or of European descent (100). Mean intraocular pressure (IOP), CCT and ECC were recorded.Results: IOP was similar between the groups (African mean IOP 15.7 ± 2.2 mmHg, ethnically diverse 15.8 ± 2.2 mmHg, European 16.0 ± 2.0 mmHg, p = 0.48). There were age differences but no gender differences between ethnic groups. Mean CCT was 503.6 ± 30.0 µm (African), 516.8 ± 30.0 µm (ethnically diverse) and 539.1 ± 34.2 µm (European) (p < 0.002 for all). Mean ECC was 2775 ± 272 cells/mm2 (African), 2678 ± 233 cells/mm2 (ethnically diverse) and 2639 ± 313 cells/mm2 (European). These differences were significant between Africans and Europeans (p = 0.001) and Africans and ethnically diverse groups (p = 0.01).Conclusion: ECC was highest in Africans with lowest CCT and conversely, Europeans demonstrated lowest ECC and highest CCT. Ethnically diverse participants demonstrated values between those of Africans and Europeans. We hypothesize that genomic research is required to determine if these differences have a genetic basis.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"56"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11785701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing early detection of keratoconus suspects using interocular corneal tomography asymmetry. 利用眼间角膜断层不对称增强圆锥角膜可疑物的早期发现。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-31 DOI: 10.1007/s10792-025-03423-7

Shuangcheng Li, Yan Huo, Ruisi Xie, Yimei Han, Haohan Zou, Yan Wang

{"title":"Enhancing early detection of keratoconus suspects using interocular corneal tomography asymmetry.","authors":"Shuangcheng Li, Yan Huo, Ruisi Xie, Yimei Han, Haohan Zou, Yan Wang","doi":"10.1007/s10792-025-03423-7","DOIUrl":"https://doi.org/10.1007/s10792-025-03423-7","url":null,"abstract":"Purpose: To evaluate corneal tomography asymmetry of both eyes in keratoconus (KC), keratoconus suspects (KCS), and normal (NL) eyes, and to introduce an interocular asymmetry index (IAI) for early diagnosis of keratoconus.Methods: This prospective case-control study included 210 NL eyes, 140 eyes with KCS, and 40 eyes with KC. New Scheimpflug imaging scans were performed to obtain corneal tomographic parameters. Based on the high and low values of tomographic parameters, each eye was categorized as \"worse\" or \"better.\" Intragroup correlation coefficients (ICC) were used to compare interocular asymmetry. Logistic regression indices were constructed using interocular differences. Receiver operating characteristic (ROC) curves were used to analyze the sensitivity, specificity, and cutoff values of the IAI.Results: In the KC group, 86.7% of the parameters significantly differed between the worse and better eyes. In the KCS group, 66.7% of the parameters showed significant differences between the worse and better eyes, with high consistency between the central and thinnest corneal thickness groups (ICC > 0.6). Strong intragroup correlations were observed in the NL group (ICC > 0.6). IAI effectively distinguished the NL from the KCS group (area under the ROC [AUROC] = 0.891), reaching 67.1% sensitivity and 97.1% specificity at a cutoff value of 0.494. At a cutoff value of 0.778, the IAI reached 95.0% sensitivity and 96.2% specificity in distinguishing NL from KC (AUROC = 0.954).Conclusion: Interocular asymmetry in keratoconus suspects can be detected in the early stages, with increased asymmetry compared to NL eyes observed as keratoconus progresses. Interocular asymmetry can complement monocular diagnostic parameters.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"55"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbiological profiles of infectious corneal ulcers in Derbyshire and North Nottinghamshire-a 10-year analysis. 德比郡和北诺丁汉郡感染性角膜溃疡的微生物谱- 10年分析。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-31 DOI: 10.1007/s10792-025-03432-6

Balázs Fazekas, Delicia Jayakumar, Harminder Singh Dua, Lana Faraj

{"title":"Microbiological profiles of infectious corneal ulcers in Derbyshire and North Nottinghamshire-a 10-year analysis.","authors":"Balázs Fazekas, Delicia Jayakumar, Harminder Singh Dua, Lana Faraj","doi":"10.1007/s10792-025-03432-6","DOIUrl":"https://doi.org/10.1007/s10792-025-03432-6","url":null,"abstract":"Purpose: To assess the spectrum of organisms causing microbial keratitis and their in-vitro anti-microbial sensitivities out of 2 hospitals in the East Midlands Region of the United Kingdom.Methods: A retrospective review was undertaken of all patients who underwent corneal scrapes for infectious keratitis between 2011 and 2021 at Royal Derby Hospital (RDH) in Derby and between 2009 and 2021 at King's Mill Hospital in Mansfield.Results: In total, the results of 645 corneal scrapes (from 622 patients) were analysed after exclusions. Of these, 307 (47.6%) yielded positive cultures. The mean patient age was 52.6 ± 22.1 years (Mean ± St Dev) across both sites and 332 (51.4%) were from female patients. At RDH, there were 195 positive corneal scrape cultures, from which 250 species of organisms were isolated. At RDH, 64% (160/250) were Gram-positive bacteria, 32% (81/250) were Gram-negative bacteria, 2.4% (6/250) were Acanthamoeba species and 1.2% were fungi (3/250). At KMH, there were 112 positive cultures, from which 128 species of organisms were isolated. 14 corneal scrapes from KMH were polymicrobial. At KMH, 96% (123/128) were bacterial (51% Gram positive, 45% Gram negative), 3/128 (2.3%) were fungi and 2/128 (1.6%) were Acanthamoeba. Sensitivity testing confirmed that the fluoroquinolone class of antibiotics appeared to be effective against the majority isolates across the two hospital sites.Conclusion: There are differences in microbiological profiles between these neighbouring hospitals covering neighbouring populations. Despite these differences, reassuringly, the current first-line fluoroquinolone monotherapy treatment is an appropriate first-line treatment for both hospital sites.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"58"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can the combination of citicoline and vitamin B12 be beneficial in the healing of corneal nerves after corneal cross-linking? 胞胆碱与维生素B12联合使用是否有利于角膜交联后角膜神经的愈合？

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-31 DOI: 10.1007/s10792-025-03433-5

Metin Unlu, Furkan Ozer, Esra Sahin Aslan, Hidayet Sener, Kuddusi Erkilic

{"title":"Can the combination of citicoline and vitamin B12 be beneficial in the healing of corneal nerves after corneal cross-linking?","authors":"Metin Unlu, Furkan Ozer, Esra Sahin Aslan, Hidayet Sener, Kuddusi Erkilic","doi":"10.1007/s10792-025-03433-5","DOIUrl":"https://doi.org/10.1007/s10792-025-03433-5","url":null,"abstract":"Purpose: To evaluate the effect of topical citicoline, vitamin B12 and hyaluronic acid (OMK2 eye drops; Omikron Italia Srl, Italy) on the healing of corneal nerve after corneal cross-linking (CXL) treatment in patients with keratoconus (KC).Methods: A total of 44 eyes of 22 patients with KC who underwent CXL were included in this prospective study. After CXL, one eye of these patients received OMK2 eye drop and standard post-CXL treatment (OMK2 group), while the fellow eye received only standard post-CXL treatment (control group). The following parameters were analyzed in the pre- and post-CXL procedure periods (1st, 3rd and 6th months): corneal sensitivity, tear film stability, central corneal thickness (CCT), and the corneal sub-basal nerve plexus (sbNP) parameters (including corneal nerve fiber density [CNFD], corneal nerve branch density [CNBD], corneal nerve fiber length [CNFL], corneal total branch density [CTBD], corneal nerve fiber area [CNFA], corneal nerve fiber width [CNFW]).Results: Following CXL, a comparison of the baseline and month 6 data revealed that CNFA decreased in the control group (p < 0.001) and did not differ in the OMK2 group (p = 0.283). Other corneal sbNP parameters exhibited a decrease when comparing baseline and 6 months in each group (all p < 0.05). In addition, CCT in the OMK2 group was not significantly different between baseline and month 6 (p = 0.052). However, a decline in CCT of the control groups was observed during this specified time interval (p = 0.009). Corneal sensitivity or tear film stability parameters did not differ significantly between groups at any time point or over time within each group (all p > 0.05).Conclusion: The use of OMK2 eye drop after CXL may provide more stable CNFA. In addition, it may also provide faster recovery in CCT.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"54"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bibliometric analysis of published works in ocular trauma: a growing focus on open globe injury. 眼外伤文献计量学分析：越来越关注开放性眼球损伤。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-29 DOI: 10.1007/s10792-025-03417-5

Hassaam S Choudhry, Eric J Kuklinski, Allen Fu, Param Shukla, Matthew Montani, Fareeda Eraky, Marco A Zarbin, Paul D Langer, Neelakshi Bhagat

{"title":"Bibliometric analysis of published works in ocular trauma: a growing focus on open globe injury.","authors":"Hassaam S Choudhry, Eric J Kuklinski, Allen Fu, Param Shukla, Matthew Montani, Fareeda Eraky, Marco A Zarbin, Paul D Langer, Neelakshi Bhagat","doi":"10.1007/s10792-025-03417-5","DOIUrl":"https://doi.org/10.1007/s10792-025-03417-5","url":null,"abstract":"Purpose: The purpose of this study is to analyze the trends and characteristics of ocular trauma research published from 2000 to 2022 to delineate the trajectory of the field's research, provide information about the network of key contributors, and help determine future research strategies and direction.Methods: Web of Science was queried for published works using a series of keywords relating to ocular trauma: \"globe rupture\", \"ruptured globe\", \"globe injury\", \"ocular trauma\", \"intraocular foreign body\", \"eye trauma\", \"eye injury\", and \"traumatic endophthalmitis\". All article information was compiled using the VOSviewer software. Article information analyzed included year of publication, publishing journal, author, institution, country, and keywords/key terms.Results: A total of 3362 articles were identified. In the time period studied, there is a noticeable trend for an increase in the number of papers pertaining to ocular trauma to be published annually. The journal, Eye published the most, and the United States produced the most articles of any country. Important keywords other than \"ocular trauma\" included \"epidemiology\", \"management\", \"children\", \"vitrectomy\" and \"endophthalmitis\".Conclusion: Complications due to ocular trauma are seen worldwide. Many different institutions, journals, and countries have published research on ocular trauma with an increased frequency in recent years. This study provides valuable information on the status of scholarly investigation of ocular trauma in the last 2 decades and sheds light on the trajectory of recent research interest.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"47"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-dimensional semi-autotamatic segmentation of nasolacrimal duct morphometry on computed tomography images. 基于ct图像的鼻泪管形态三维半自动分割。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-29 DOI: 10.1007/s10792-025-03416-6

Kadriye Betul Pence, Nureda Nalcaci Bozkurt, Bahar Tekin, Selva Sen, Gamze Ansen, Tugrul Ormeci, Neslihan Yuzbasioglu

{"title":"Three-dimensional semi-autotamatic segmentation of nasolacrimal duct morphometry on computed tomography images.","authors":"Kadriye Betul Pence, Nureda Nalcaci Bozkurt, Bahar Tekin, Selva Sen, Gamze Ansen, Tugrul Ormeci, Neslihan Yuzbasioglu","doi":"10.1007/s10792-025-03416-6","DOIUrl":"https://doi.org/10.1007/s10792-025-03416-6","url":null,"abstract":"Purpose: Given the potential role of nasolacrimal duct (NLD) morphometry in the aetiology of primary acquired obstructions, it is imperative that clinicians have access to detailed anatomical information. The aim of this study was to determine normative data on nasolacrimal duct morphometry in the Turkish population sample and to provide guidelines for clinicians.Methods: The study included retrospectively computed tomography images of a healthy Turkish population sample of 151 individuals, 79 of whom were female and 72 of whom were male. Images were modeled and analyzed using 3D Slicer version 5.2.2.Results: The total volume and area of the NLD were smaller in females than in males. The right- and left-sided volume of the NLD were smaller in females than in males (In male, right side 219.28 ± 77.53 mm3 and left side 213.14 ± 73.82 mm3; in female, right side 193.82 ± 75.71 mm3, left side, 190.34 ± 82.54 mm3). Although the anteroposterior and transverse diameters of the right-sided NLD were not statistically different between the genders, the anteroposterior and transverse diameters of the left-sided NLD and distance between right and left NLD were smaller in female than in males. The volume and surface area of the right-sided NLD and the distance between the right and left NLD were larger with increasing age. The anteroposterior diameter was observed to be larger on the right side than on the left in both sexes, whereas the transverse diameter was larger on the right side than on the left side exclusively in females.Conclusion: The results of this study may assist clinicians in the surgical approaches.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"46"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary steroids in acute central serous chorioretinopathy. 唾液类固醇治疗急性中枢性浆液性脉络膜视网膜病变。

IF 1.4 4区医学

International Ophthalmology Pub Date : 2025-01-29 DOI: 10.1007/s10792-025-03422-8

Dmitrii S Maltsev, Alexei N Kulikov, Alexander S Vasiliev, Jay Chhablani

{"title":"Salivary steroids in acute central serous chorioretinopathy.","authors":"Dmitrii S Maltsev, Alexei N Kulikov, Alexander S Vasiliev, Jay Chhablani","doi":"10.1007/s10792-025-03422-8","DOIUrl":"https://doi.org/10.1007/s10792-025-03422-8","url":null,"abstract":"Purpose: To analyze levels of salivary steroids, including 17-OH-progesterone (17-OHP), androstenedione, dehydroepiandrosterone, cortisol, cortisone, progesterone, testosterone, and estradiol, in patients with acute central serous chorioretinopathy (CSCR) patients.Methods: Acute CSCR patients and healthy individuals were included in this observational case-control study. Levels of salivary steroids were determined by high-performance liquid chromatography with tandem mass spectrometry detection. Clinical characteristics of CSCR patients were assessed based on multimodal imaging.Results: Seventeen CSCR patients (40.1 ± 4.6 years) and fourteen age-matched healthy controls (40.6 ± 3.8 years) were included. Mean central retinal thickness and subfoveal choroidal thickness in affected eye of CSCR patients were 436.2 ± 131.1 µm and 464.6 ± 132.6 µm, respectively. Mean best-corrected visual acuity was 0.09 ± 0.11 LogMAR. Mean symptoms duration before saliva collection was 0.9 ± 0.6 months. 17-OHP was decreased compared to the normal limits established in healthy controls in 10 out of 17 patients (59%), androstenedione in 15 out of 17 patients (88%), dehydroepiandrosterone in 10 out of 17 patients (59%), cortisol in 6 out of 17 patients (35%), cortisone in 12 out of 17 patients (83%), progesterone in 9 out of 17 patients (53%), testosterone in 10 out of 17 patients (59%), and estradiol in 5 out of 17 patients (29%). In total, among CSCR patients lower level in saliva was found for all studied hormones (p < 0.05), except progesterone and estradiol.Conclusion: Salivary steroids are decreased in acute CSCR male patients compared with age-matched controls. This may indicate inhibition of steroidogenesis caused by chronic stress and personal reactivity preceding manifestation of CSCR.","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"49"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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