International Ophthalmology最新文献

{"title":"The effect of caffeine consumption on age-related macular degeneration: a systematic review and meta-analysis.","authors":"Jennifer Electra, Elvina Theodoraliu, Gilbert Lazarus, Yeni Dwi Lestari, Ari Djatikusumo","doi":"10.1007/s10792-025-03531-4","DOIUrl":"https://doi.org/10.1007/s10792-025-03531-4","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the state-of-the-art evidence on the effect of caffeine consumption on the development and progression of age-related macular degeneration (AMD), a significant cause of blindness worldwide.</p><p><strong>Methods: </strong>Eligible primary clinical studies published up to 15 June 2024 were included and appraised using the Joanna Briggs Institute critical appraisal tools for cohort and case-control studies. The available data were then analyzed using random-effects meta-analysis and effect direction-based vote-counting (PROSPERO CRD42023451237).</p><p><strong>Results: </strong>Five studies (9318 patients) were included in this systematic review, three of which investigated the effect of caffeine intake on the development of AMD and two on AMD progression. Caffeine intake from coffee or other beverages showed no significant association with the occurrence of early (adjusted odds ratio 1.11 [95% confidence interval 0.93-1.33], I² = 0.0%) or late AMD. On the other hand, vote-counting analysis indicated that caffeine consumption, mainly tea, may prevent and hinder disease progression, potentially in a dose-dependent manner.</p><p><strong>Conclusion: </strong>The limited available evidence suggests that caffeine consumption may deter and impede the progression of AMD. In contrast, the protective effect of caffeine consumption on the development of AMD remains uncertain. Further prospective, large-scale studies exploring the effects and dose-response relationship of various caffeine beverages across a broader spectrum of AMD and populations are warranted to corroborate our findings.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"158"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid-related orbitopathy: clinical overview, novel medical treatments and the role of orbital surgery.","authors":"Federico Giannuzzi, Matteo Mario Carlà, Emanuele Crincoli, Gloria Gambini, Lorenzo Hu, Francesco Boselli, Giovanni Cuffaro, Claudio Parrilla, Mario Rigante, Monica Maria Pagliara, Stanislao Rizzo, Gustavo Savino","doi":"10.1007/s10792-025-03535-0","DOIUrl":"https://doi.org/10.1007/s10792-025-03535-0","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of our review is to report the thyroid orbitopathy treatments, focusing on novel medicines and ongoing research.</p><p><strong>Design: </strong>Review developed by a research group at Catholic University of the Sacred Heart.</p><p><strong>Methods: </strong>Overview of the literature synthesizing the findings of literature retrieved from searches of computerized databases, hand searches and authoritative texts. Although minimally invasive surgical techniques have been developed, current research is placing greater emphasis on the use of biological and immunosuppressive drugs for the treatment of thyroid eye disease (TED). Teprotumumab, a monoclonal antibody targeting the insulin-like growth factor-1 receptor, has just been approved by the Food and Drug Administration as a therapy for the treatment of TED. This approval is based on its ability to relieve both the clinical signs and symptoms of the condition, such as proptosis and diplopia. Synthetic peptides imitating T cell epitopes and TSHR-CAR-T cells represent a potential and novel immunotherapeutic strategy.</p><p><strong>Conclusions: </strong>The growth of several novel therapies highlights the intricate nature of the disease's aetiology and the multitude of processes involved in its regulation. These advancements reveal a future direction focused on personalized treatment of Graves' orbitopathy. The integration of multiple disciplines is becoming increasingly indispensable in the management of patients with this disease.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"160"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Internal drainage of subretinal fluid during scleral buckling with 27-Gauge wide angle viewing system and flute needle for rhegmatogenous retinal detachment.","authors":"Lijun Xie, Gang Qiao, Xiaojuan Zhang, Ziyan Tang, Qiangxing Zou, Chunmei He, Kui Cao, Wanjiang Dong, Wenyong Liao, Dongbin Chen","doi":"10.1007/s10792-025-03533-2","DOIUrl":"10.1007/s10792-025-03533-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the clinical therapeutic effects and advantages of internal drainage of subretinal fluid using a 27-gauge wide-angle viewing system(WAVS) and a flute needle compared with external drainage of subretinal fluid (SRF) during scleral buckling for the treatment of rhegmatogenous retinal detachment (RRD).</p><p><strong>Methods: </strong>In this prospective randomized case series at two hospitals, we evaluated 43 eyes of 43 patients with RRD who were divided into two groups, A and B. Twenty-two eyes (22 patients) in Group A underwent internal drainage of subretinal fluid with a 27-gauge WAVS and a flute needle, whereas 21 eyes (21 patients) in Group B underwent external drainage of subretinal fluid during scleral buckling surgery. The duration of surgery, rates of retinal reattachment, best corrected visual acuity (BCVA), intraocular pressure (IOPs), occurrence of recurrent RRD, and risk factors of intraoperative or postoperative complications, including subretinal hemorrhage, vitreous hemorrhage, persistent subretinal fluid, postoperative retinal tear, choroidal detachment, vitreous loss, vitreous and retinal incarceration, cystoid macular edema, cataract, glaucoma, and endophthalmitis, of both groups were collected and compared. We followed up these patients for six months after surgery.</p><p><strong>Results: </strong>The mean operating time of Group A (53.36 ± 6.19 min) was significantly shorter than Group B (61.24 ± 6.84 min) (P = 0.00). The final anatomical success rates were 100%(22/22) and 90.48%(19/21) in Group A and B, respectively (P = 0.14). All detached retinas in Group A reattached before the final follow-up, and no intraoperative or postoperative complications were detected. In Group B, 2(9.52%, 2/21) underwent a second vitrectomy surgery because of subretinal hemorrhage during external drainage of the subretinal fluid. However, the retinas of both eyes reattached at the end of the final follow-up. However, there were two (9.52%, 2/21) other eyes' retinas in Group B that had not completely reattached due to persistent subretinal fluid at the end of this study. The final mean BCVA of Group A (0.21 ± 0.15) was significantly superior to that of Group B(0.39 ± 0.35)(P = 0.04). The intraocular pressure in all the patients was within the normal range throughout the study.</p><p><strong>Conclusion: </strong>Although limited by the small sample size, this study suggests that internal drainage of subretinal fluid during scleral buckling with 27-gauge WAVS and flute needle showed advantages superior to external drainage of subretinal fluid in scleral buckling surgery, including increased efficiency and decreased amount of SRF, shortened duration of persistent subretinal fluid, and reduced rate of subretinal hemorrhage.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"159"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior segment and Schlemm's canal alterations during the menstrual cycle in reproductive-age Turkish women.","authors":"Işıl Merve Torun, Hasine Gözde Dalkiliç, Gülcan Toplak, Murat Sönmez","doi":"10.1007/s10792-025-03547-w","DOIUrl":"https://doi.org/10.1007/s10792-025-03547-w","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate variations in central corneal thickness (CCT), corneal aberrations, and anterior chamber depth througout the follicular and luteal phases of the menstrual cycle in reproductive-age women with regular menstruation using corneal topography and changes in Schlemm's canal (SC) diameter and area using the anterior segment (AS) module of enchanced depth imaging optical coherence tomography (EDI-OCT).</p><p><strong>Methods: </strong>Corneal topography and AS-EDI-OCT of 69 volunteers included in this prospective study were performed between days 1-5 of the cycle for the follicular phase and between days 25-35 for the luteal phase. SC diameter and area calculations were calculated using the ImageJ software.</p><p><strong>Results: </strong>During the luteal phase, there was a significant increase in CCT and SC diameter and trefoil 0° aberrations compared with the follicular phase. Additionally, a significant positive correlation was obtained between intraocular pressure and SC diameter, and a significant negative correlation between CCT and SC diameter and area.</p><p><strong>Conclusions: </strong>Changes in corneal and anterior chamber angle were observed due to hormonal changes in the menstrual cycle. This is the first study to investigate the changes in SC diameter and area and corneal aberrations during the menstrual cycle.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"166"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Astigmatic vector analysis after combined surgery for forme fruste keratoconus.","authors":"Ayhan Sağlık, Ali Şimşek","doi":"10.1007/s10792-025-03546-x","DOIUrl":"https://doi.org/10.1007/s10792-025-03546-x","url":null,"abstract":"<p><strong>Purpose: </strong>The Alpins vector analysis approach was used to assess astigmatic changes in eyes with forme fruste keratoconus following combination treatment with photorefractive keratectomy (PRK) and corneal collagen crosslinking (CXL).</p><p><strong>Methods: </strong>This retrospective study was performed in 27 eyes from 20 patients with forme fruste keratoconus undergoing treatment with a combination of PRK, followed immediately by corneal collagen CXL. Spherical error, corneal astigmatism, and manifest astigmatism were assessed preoperatively and at 12 months postoperatively. Scheimpflug imaging was used to determine the thinnest corneal thickness, maximum keratometry (Kmax), steep keratometry (K2), and flat keratometry (K1). Alpins vector analysis was used to evaluate the corneal and refractive astigmatism vectors.</p><p><strong>Results: </strong>The patients ranged in age from 18 to 35 years, with a mean of 22.00 ± 1.16 years. Unilateral surgery was performed in 7 patients, whereas 13 patients underwent bilateral surgery. After surgery, logMAR corrected distance visual acuity improved from 0.22 ± 0.04 to 0.06 ± 0.01 (p < 0.001). On examination of corneal astigmatism, the difference vector (DV) mean was 0.49 diopters (D) at axis 13°, the arithmetic mean was 0.96 D, and the correction index (CI) geometric mean was 0.64. On examination of manifest or refractive astigmatism, the DV mean was 0.10 D at axis 16°, the arithmetic mean was 0.63 D, and the geometric mean CI was 0.89.</p><p><strong>Conclusion: </strong>Patients with forme fruste keratoconus with sufficient corneal thickness may benefit from a combination of surface ablation and crosslinking surgery. Astigmatic changes induced by this treatment can be examined more objectively using Alpins vector analysis.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"165"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of topographic, aberrometric, and endothelial cell features of the cornea in Fabry disease.","authors":"Kübra Kahraman Koç, Nesrin Büyüktortop Gökçinar, Selda Fatma Bülbül","doi":"10.1007/s10792-025-03550-1","DOIUrl":"https://doi.org/10.1007/s10792-025-03550-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated topographic, aberrometric, and endothelial cell characteristics of the cornea in Fabry disease and compared them to healthy eyes.</p><p><strong>Methods: </strong>This prospective, cross-sectional study included 21 patients with Fabry disease and 41 healthy volunteers in Fabry disease (FG) and control (CG) groups, respectively. After ophthalmological examinations, the topographic, tomographic, and aberrometric corneal data were acquired using a Scheimpflug-Placido disk system anterior segment analysis device. The corneal endothelial examination was conducted using a specular microscopy device, and results were compared. A p-values of < 0.05 were considered statistically significant.</p><p><strong>Results: </strong>No significant differences were noted between the age and gender of the groups (p > 0.05). Central and thinnest corneal thickness were significantly lower in the FG than in the CG (p = 0.036 and 0.023, respectively). Although the aberrometric values of the cornea were usually higher in the FG, this difference was not significant. No significant differences were observed between the two groups regarding corneal endothelial data examined by specular microscopy. When the eye data with cornea verticillata in the FG were compared with those of the CG, anterior higher-order aberrations (HOA) were significantly higher in the FG (p = 0.047) than in the CG.</p><p><strong>Conclusions: </strong>Cornea verticillata associated with Fabry disease can increase HOA in the eye.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"169"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolving indications and surgical trends in keratoplasty: a 7-year analysis from a Chinese tertiary referral center.","authors":"Xiaoxuan Wu, He Yu, Liang Yu, Lili Ji, Qiming Liu, Jian Song, He Dong","doi":"10.1007/s10792-025-03548-9","DOIUrl":"https://doi.org/10.1007/s10792-025-03548-9","url":null,"abstract":"<p><strong>Background: </strong>The objectives of this study were to investigate the epidemiological characteristics and spectrum of corneal primary diseases among keratoplasty patients in the southern region of Liaoning Province and to study the changing trends in keratoplasty types and corneal graft materials.</p><p><strong>Methods: </strong>The medical records of 537 patients who underwent keratoplasty at the Department of Ophthalmology of Dalian Third People's Hospital from 2017 to 2023 were retrospectively analyzed. Patient demographic (age and sex), primary corneal disease type, keratoplasty type and corneal graft material data were statistically analyzed.</p><p><strong>Results: </strong>A total of 537 patients who underwent keratoplasty during the 7 years study period were included. The average age of the patients was 56.35±15.93 years, ranging from 5 to 90 years. There were 348 male patients (64.8%) and 189 female patients (35.2%), with a ratio of 1.84:1. Among the primary corneal diseases, infectious keratitis was the most common (243, 45.25%), followed by corneal leukoma (73, 13.59%), corneal endothelial decompensation (48, 8.94%), traumatic corneal injury (36, 6.70%), corneal graft rejection (34, 6.33%), immune corneal ulcer (33, 6.15%), keratoconus (32, 5.96%), corneal dystrophy and degeneration (28, 5.21%), and corneal tumor (10, 1.86%). Among infectious keratitis cases, the detailed etiology was as follows: fungal keratitis (154, 63.37%), bacterial keratitis (54, 22.22%), viral keratitis (34, 13.99%), and Acanthamoeba keratitis (1, 0.41%). According to the classification of ker atoplasty types, the most common was PKP (265, 49.35%), followed by DALK (129, 24.02%), ALK (116, 21.60%), and EK (27, 5.03%). PKP is still the main surgical method for corneal transplantation, but the proportions of patients who undergo DALK, ALK, and EK are increasing. The corneal graft materials were classified as fresh human donor corneal grafts (297, 55.31%), dehydrated human donor corneal grafts (166, 30.91%), corneal stromal lenticules (4, 0.74%), and bioengineered corneal grafts (70, 13.04%).</p><p><strong>Conclusion: </strong>Owing to factors such as economic development and industrial distribution, infectious keratitis is the primary cause of keratoplasty in the southern Liaoning region of China, followed by corneal leukoma and corneal endothelial decompensation. Fungal infection is the leading cause of infectious keratitis. The primary keratoplasty type has shifted from PKP to corneal composition transplantation. The range of materials utilized for corneal grafts has expanded significantly and now includes corneal stroma lenticules and bioengineered corneal grafts, in addition to human donor corneal grafts. The present study delineates the evolving surgical patterns and material innovations related to keratoplasty, providing insights for regional ophthalmic policy-making.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"167"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Choroidal thickness and vascularity in diabetic macular edema: impact of serous macular detachment.","authors":"Ayşenur Paşaoğlu, Mahmut Erkam Arslan, Ender Sirakaya","doi":"10.1007/s10792-025-03541-2","DOIUrl":"https://doi.org/10.1007/s10792-025-03541-2","url":null,"abstract":"<p><strong>Purpose: </strong>This comparative study aimed to investigate the role of the choroidal vascular system in the formation of serous macular detachment (SMD) in diabetic macular edema (DME).</p><p><strong>Methods: </strong>A study population of 126 naive patients was divided into two groups: group 1 (DME without serous macular detachment, n = 90) and group 2 (DME with serous macular detachment, n = 36). The following assessments were conducted: best corrected visual acuity (BCVA), central macular thickness (CMT), the height of the SMD, subfoveal central choroidal thickness (SFCT), choroidal thickness at the nasal (SFNCT) and temporal (SFTCT) borders of the subfoveal 1500-micron area, choroidal thickness at the nasal (SMNCT) and temporal (SMTCT) borders of the submacular 6000-micron area, and subfoveal and submacular choroidal vascularity index (CVI).</p><p><strong>Results: </strong>BCVA was significantly better in group 1, whereas CMT was greater in group 2 (p = 0.002, p < 0.001, respectively). The logMAR BCVA was positively correlated with CMT in both groups (p < 0.001 for both, r = 0.940, and r = 0.920, respectively), but BCVA was not significantly correlated with SFCT, CVI or submacular CVI. Group 2 also showed significantly greater values for SFCT, SFNCT and SFTCT (p < 0.001) and SMNCT (p = 0.046); whereas SMTCT values showed no significant difference (p = 0.074). With regard to the subfoveal and submacular CVI, no significant differences were found between the groups (p = 0.142, p = 0.468).</p><p><strong>Conclusion: </strong>While the presence of SMD in DME affects choroidal thickness, no significant difference was observed in the choroidal vascularity index. These findings may enlighten SMD pathogenesis, supporting the hypothesis that choroidal changes are not directly linked to alterations in vascular structure.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"162"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of inferior visual field on frail status in glaucoma patients.","authors":"Yoshitaka Takizawa, Takanori Ro, Masataka Murono, Takayuki Kamiya, Youngseok Song, Tetsuo Ota, Reiko Kinouchi","doi":"10.1007/s10792-025-03549-8","DOIUrl":"https://doi.org/10.1007/s10792-025-03549-8","url":null,"abstract":"<p><strong>Purpose: </strong>To elucidate the association between frail status and regions of visual field (VF) defect in glaucoma patients, and assess the cut-off threshold of VF defect and visual acuity that should give attention to frailty.</p><p><strong>Methods: </strong>In this cross-sectional study, we recruited 52 glaucoma patients aged 70 to 89 years. We utilized the Fried frailty criteria to evaluate frailty status. We divided the binocular-integrated VF into four regions and analyzed the association between those divided VF and frail status. The receiver operating characteristic (ROC) analysis was performed to assess the cut-off threshold of VF and visual acuity (LogMAR) to be prefrailty.</p><p><strong>Results: </strong>Twenty-three were defined as robust, 24 were prefrail, three were frail, and two patients missed a questionnaire to determine frailty. All four regions of VF were significantly associated with the number of frailty criteria met. The results of structural equation modeling for frailty indicated a larger standardized factor loading in inferior VF than in superior VF. The ROC curve for detection of the combined prefrailty and frailty showed the cut-off threshold of the inferior central VF total deviation was - 3.75 (AUC: 0.825), and that of the worse eye's LogMAR was 0.22 (AUC: 0.810).</p><p><strong>Conclusions: </strong>The impact of the inferior VF on frailty was evident in glaucoma patients. Even minor inferior visual field defects and mild visual acuity loss in the worse eye suggest the need for interventions not to develop frailty in glaucoma patients.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"168"},"PeriodicalIF":1.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pilestone glasses for color blindness: the effect on chromatic discrimination in subjects with congenital color deficiency.","authors":"Esraa S El-Ghoubashy, Alaa M Saleh","doi":"10.1007/s10792-025-03508-3","DOIUrl":"https://doi.org/10.1007/s10792-025-03508-3","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to assess how well the Pilestone color vision glasses worked to improve test results for color deficiency based on the Ishihara color vision test.</p><p><strong>Methods: </strong>Following their consent, sixteen people with color vision defects were enrolled. The Ishihara test was used to evaluate color vision. The incorrect scores were noted. After using Pilestone glasses for color vision impairment, the test was repeated.</p><p><strong>Results: </strong>The median error score was 20 (18-20) on Ishihara. The median error scores were reduced to 8 (1-18.75). Ten patients were satisfied with result of intervention (62.5%) while (37.5%) were non-satisfied.</p><p><strong>Conclusion: </strong>This study demonstrates that individuals were able to pass the color vision tests and that the Pilestone glasses which is the cheapest glasses in the market decreased error scores. Additionally, it might enhance the subjective look of the colorful things in the surrounding.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"45 1","pages":"157"},"PeriodicalIF":1.4,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}