Anterior segment and Schlemm's canal alterations during the menstrual cycle in reproductive-age Turkish women.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2025-05-03 DOI:10.1007/s10792-025-03547-w

Işıl Merve Torun, Hasine Gözde Dalkiliç, Gülcan Toplak, Murat Sönmez

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引用次数: 0

Abstract

Purpose: To investigate variations in central corneal thickness (CCT), corneal aberrations, and anterior chamber depth througout the follicular and luteal phases of the menstrual cycle in reproductive-age women with regular menstruation using corneal topography and changes in Schlemm's canal (SC) diameter and area using the anterior segment (AS) module of enchanced depth imaging optical coherence tomography (EDI-OCT).

Methods: Corneal topography and AS-EDI-OCT of 69 volunteers included in this prospective study were performed between days 1-5 of the cycle for the follicular phase and between days 25-35 for the luteal phase. SC diameter and area calculations were calculated using the ImageJ software.

Results: During the luteal phase, there was a significant increase in CCT and SC diameter and trefoil 0° aberrations compared with the follicular phase. Additionally, a significant positive correlation was obtained between intraocular pressure and SC diameter, and a significant negative correlation between CCT and SC diameter and area.

Conclusions: Changes in corneal and anterior chamber angle were observed due to hormonal changes in the menstrual cycle. This is the first study to investigate the changes in SC diameter and area and corneal aberrations during the menstrual cycle.

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土耳其育龄妇女月经周期中前段和施勒姆管的改变。

目的：利用角膜地形图研究月经规律的育龄女性在月经周期的卵泡期和黄体期的角膜中央厚度（CCT）、角膜像差和前房深度的变化，并利用增强深度成像光学相干断层扫描（edii - oct）的前段（AS）模块研究Schlemm’s canal （SC）直径和面积的变化。方法：在卵泡期周期的第1-5天和黄体期的第25-35天之间对69名志愿者进行角膜地形图和AS-EDI-OCT检查。利用ImageJ软件计算SC直径和面积。结果：与卵泡期相比，黄体期CCT、SC直径和三叶0°像差明显增加。眼压与SC直径呈显著正相关，CCT与SC直径及面积呈显著负相关。结论：经期激素变化可引起角膜和前房角的改变。这是第一个研究月经周期中SC直径、面积和角膜像差变化的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.