International Ophthalmology最新文献

{"title":"Comparative safety and complication profiles of two three-piece intraocular lenses in Yamane technique.","authors":"Erdi Karadağ, Güzide Akçay, Burak Tanyıldız, Ulviye Kıvrak, Esengül Kuş Solmaz","doi":"10.1007/s10792-026-04289-z","DOIUrl":"https://doi.org/10.1007/s10792-026-04289-z","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the mechanical behavior, intraoperative events, and postoperative outcomes of two three-piece intraocular lenses (IOLs) with different haptic materials-polymethyl methacrylate (PMMA) and polyvinylidene fluoride (PVDF)-implanted using the Yamane fixation technique.</p><p><strong>Methods: </strong>This retrospective comparative study included eyes undergoing Yamane scleral fixation with either a PMMA-haptic IOL (Alcon MA60AC) or a PVDF-haptic IOL (Eyecryl Plus TP613). Preoperative and postoperative month 6 best-corrected visual acuity (BCVA), intraocular pressure (IOP), and cylindrical refraction, as well as intraoperative haptic-related complications including haptic tip breakage and optic-haptic junction separation, postoperative IOL dislocation, and other postoperative complications were recorded and analyzed.</p><p><strong>Results: </strong>Seventy-four eyes (37 per group) were included. Baseline demographic and preoperative clinical characteristics were similar between groups. At 6 months, BCVA improved significantly in both groups without a significant intergroup difference, and postoperative IOP values and cylindrical refraction were comparable. Intraoperative complications were more frequent in the Alcon group (32.4%, 95% CI 19.6-48.5% vs. 5.4%, 95% CI 1.5-17.7%; p = 0.003), with haptic-related complications occurring exclusively in this group. Overall postoperative complication rates were similar; however, IOL dislocation occurred only in the Alcon group (16.2%, 95% CI 7.7-31.1% vs. 0%; p = 0.025). Other postoperative complications did not differ significantly.</p><p><strong>Conclusion: </strong>Both IOLs yielded comparable improvements in visual acuity; however, all haptic-related complications and IOL dislocations occurred exclusively in the Alcon MA60AC group. These findings suggest that IOL selection is an important consideration in Yamane fixation, and the Eyecryl Plus TP613 with its PVDF haptics and more favorable design profile may offer greater biomechanical reliability.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual, refractive, and tomographic outcomes after mitomycin-free manual superficial keratectomy for Salzmann nodular degeneration and peripheral hypertrophic subepithelial corneal degeneration: a retrospective cohort study.","authors":"Sofie Mourisse, Isabeau Houben, Thierry Derveaux, Ineke van Gremberghe, Elke O Kreps, Dimitri Roels","doi":"10.1007/s10792-026-04292-4","DOIUrl":"https://doi.org/10.1007/s10792-026-04292-4","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate visual, refractive, keratometric, aberrometric, and densitometric outcomes after manual superficial keratectomy (MSK) without adjuvant mitomycin C (MMC) for Salzmann nodular degeneration (SND) and peripheral hypertrophic subepithelial corneal degeneration (PHSCD).</p><p><strong>Methods: </strong>Retrospective cohort study of patients treated with MSK without adjuvant MMC at Ghent University Hospital. Outcomes included best-corrected visual acuity (BCVA), refraction, and Scheimpflug-based tomography, aberrometry, and densitometry (Pentacam HR). Recurrence and complications were recorded throughout follow-up.</p><p><strong>Results: </strong>Pre- and postoperative outcomes were compared in 56 eyes of 38 patients (50 SND, 6 PHSCD) over a median follow-up of 4.6 (mean 13.8) months (maximum 6.4 years). BCVA improved from 0.20 to 0.08 logMAR, spherical equivalent from + 1.51 to - 0.85 D, refractive cylinder from - 4.56 to - 1.24 D, and corneal astigmatism from 4.31 to 1.40 D (all P < 0.001). K1 increased from 38.92 to 42.26 D (P < 0.001), with a smaller increase in K2 (43.25 to 43.67 D; P = 0.009). Higher-order root-mean-square aberrations decreased from 2.79 to 1.12 µm (P < 0.001) and total root-mean-square aberrations from 7.30 to 3.27 µm (P < 0.001). Corneal densitometry did not change significantly in any prespecified zone. Nodular recurrence occurred in one eye (1.8%); secondary pterygia developed in 4 eyes (7.1%); no intraoperative complications occurred.</p><p><strong>Conclusions: </strong>In this retrospective cohort of eyes with SND or PHSCD, MSK without adjuvant MMC was associated with significant visual, refractive, keratometric, and aberrometric improvement. We consider this approach an effective first-line surgical option in symptomatic or visually significant SND and PHSCD.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical outcomes, cost, and patient perceptions between delayed and immediate sequential bilateral cataract surgery in Thailand: a retrospective case-control study.","authors":"Aim-On Saengsirinavin, Thiti Wichayachiwin, Thanida Voraviwat, Frances Andrea Anover, Ngoc Trong Tuong Than, Negin Yavari, Jia-Horung Hung, Jingli Gou, Christopher Or, Quan Dong Nguyen, Prin Rojanapongpun","doi":"10.1007/s10792-026-04271-9","DOIUrl":"10.1007/s10792-026-04271-9","url":null,"abstract":"<p><strong>Purpose: </strong>To compare clinical outcomes, complication rates, costs, and patient perceptions-encompassing satisfaction, anxiety, pain, and visual function-between delayed sequential bilateral cataract surgery (DSBCS) and immediately sequential bilateral cataract surgery (ISBCS) in Thailand.</p><p><strong>Setting: </strong>King Chulalongkorn Memorial Hospital (KCMH) and Sukhumvit Hospital, Bangkok, Thailand.</p><p><strong>Methods: </strong>A retrospective comparative study was performed, including 201 adult patients (402 eyes) who underwent DSBCS (n = 99) or ISBCS (n = 102), performed by a single surgeon between January 2016 and December 2023. Patient perceptions were assessed through structured interviews.</p><p><strong>Results: </strong>No major intraoperative or postoperative complications-including posterior capsule rupture or endophthalmitis-were observed in either group. Postoperative visual acuity (LogMAR) and refraction within ±0.5D of target were comparable between groups (61.6% DSBCS vs 65.5% ISBCS, p = 0.485). ISBCS patients reported significantly higher anxiety scores (median 3 vs 2, p = 0.002) and lower satisfaction scores (median 8 vs 10, p < 0.001) than DSBCS patients. ISBCS patients also reported significantly higher pain during surgery (p < 0.001). DSBCS patients demonstrated greater improvement in near visual function, specifically reading (median improvement 3 vs 2, p = 0.021) and computer use (p < 0.001). The total healthcare cost was significantly higher for DSBCS (USD 1,624 [IQR 1,492-4,029]) compared to ISBCS (USD 1,012 [IQR 910-1,839]) (p < 0.001).</p><p><strong>Conclusion: </strong>Safety and efficacy outcomes were equivalent for DSBCS and ISBCS. However, ISBCS patients reported higher anxiety, greater pain during surgery, and lower satisfaction compared to DSBCS. DSBCS patients demonstrated greater improvement in near visual function. The overall cost was significantly lower for ISBCS, a finding consistent across both government and private hospital settings. These results highlight the need for interventions to reduce perioperative anxiety and pain in ISBCS patients, and provide Thai-specific evidence to inform healthcare policy decisions regarding the wider implementation of ISBCS.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual outcomes and short-term complication profile following Yamane scleral fixation of intraocular lenses across different surgical indications.","authors":"Ahmad Kunbaz, Esma Ecem Ersoy, Fatime Ucdag, Batuhan Borucu, Fehim Esen, Ebubekir Durmus, Halit Oguz, Veysel Aykut","doi":"10.1007/s10792-026-04294-2","DOIUrl":"https://doi.org/10.1007/s10792-026-04294-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate visual and safety outcomes of double-flanged (Yamane) intrascleral intraocular lens fixation across different clinical scenarios of capsular support loss.</p><p><strong>Methods: </strong>This retrospective cohort study included 55 eyes undergoing Yamane scleral fixation. Eyes were stratified by surgical indication into aphakia (10), dislocated intraocular lens (12), complicated phacoemulsification (15), and dropped intraocular lens managed with pars plana vitrectomy (18). Best-corrected visual acuity, intraocular pressure, and postoperative complications were assessed preoperatively and at 1-week, 1-month, and 3-month follow-up. Multivariable regression analysis was performed to evaluate associations between clinical factors and final visual acuity.</p><p><strong>Results: </strong>Best-corrected visual acuity improved significantly in all groups (p < 0.001), with no intergroup differences at any postoperative time point (all p > 0.05). Postoperative intraocular pressure remained comparable across groups (p > 0.05). Early postoperative complications were more frequent in the phacoemulsification with scleral fixation group (p = 0.01), primarily transient corneal edema (93.3%) and transient intraocular pressure elevation (53.3%). Lens-related complications, including iris optic capture, intraocular lens tilt, and intraocular lens dislocation, each occurred in 6.7% and required surgical repositioning. Later postoperative complication rates at 1 and 3 months were comparable among groups. Postoperative refractive outcomes, including spherical equivalent and prediction error, were comparable across all surgical indications, with no significant intergroup differences (all p > 0.05).</p><p><strong>Conclusions: </strong>Yamane scleral fixation was associated with consistent short-term visual improvement and an acceptable short-term complication profile across a broad range of clinical indications in eyes without capsular support. Combined cataract extraction with scleral fixation was associated with visual outcomes comparable to isolated secondary intraocular lens fixation but was associated with a higher incidence of early postoperative complications.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral eplerenone in first-episode acute central serous chorioretinopathy: results of a double-masked randomized trial.","authors":"Ghodsieh Zamani, Roozbeh Asghari, Nasser Shoeibi, Majid Abrishami, Seyedeh Maryam Hoseini, Mohammad-Reza Ansari-Astaneh, Mojtaba Abrishami, Elham Bakhtiari, Mehrdad Motamed Shariati","doi":"10.1007/s10792-026-04287-1","DOIUrl":"10.1007/s10792-026-04287-1","url":null,"abstract":"<p><strong>Background: </strong>Central serous chorioretinopathy (CSCR) is a pachychoroid disorder characterized by serous retinal detachment driven by choroidal vascular dysfunction and mineralocorticoid receptor (MR) overactivation. Eplerenone, a selective MR antagonist, has been proposed as a therapeutic option, although clinical evidence remains inconsistent.</p><p><strong>Methods: </strong>In a randomized, double-blind, placebo-controlled trial, 44 patients with first-episode acute CSCR received either oral eplerenone (25 mg twice daily) or placebo for three months. Outcomes included best-corrected visual acuity (BCVA), central macular thickness (CMT), subretinal fluid (SRF) height, subfoveal choroidal thickness (CT), and OCT-angiography parameters of retinal and choroidal microvasculature.</p><p><strong>Results: </strong>Both groups demonstrated significant reductions in CMT and SRF over time, but SRF absorption was significantly greater in the eplerenone group at 3 months (P < 0.05). Choriocapillaris vessel density and flow index improved significantly with eplerenone (P < 0.001), while superficial, deep, and radial peripapillary plexus densities did not differ between groups. BCVA improved similarly in both groups.</p><p><strong>Conclusion: </strong>Eplerenone accelerates SRF resolution and enhances choriocapillaris perfusion in acute CSCR, although visual outcomes remain comparable to placebo. Early MR antagonism may offer anatomical and microvascular benefits in CSCR management.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and correlation analysis of CDFI in contralateral healthy eye in patients with CRAO.","authors":"Hongxia Gong, Shiyonog Xie, Tongmei Zhang","doi":"10.1007/s10792-026-04288-0","DOIUrl":"10.1007/s10792-026-04288-0","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate hemodynamic changes in the ophthalmic artery(OA) and central retinal artery(CRA) of contralateral healthy eyes in patients with central retinal artery occlusion (CRAO) and their correlation with the affected eye.</p><p><strong>Methods: </strong>This study included 36 patients with CRAO(affected eye group), 32 healthy contralateral eyes(healthy eye group), and 34 healthy volunteers(control group). All participants underwent comprehensive ophthalmic examinations, including best-corrected visual acuity(BCVA, converted to LogMAR for analysis), slit-lamp microscopy, indirect ophthalmoscopy, intraocular pressure measurement, and color Doppler flow imaging (CDFI). Patients with CRAO also underwent fundus fluorescein angiography(FFA) within 3 days of presentation.</p><p><strong>Results: </strong>Compared to the control group, the systolic peak velocity(Oamax) of the OA was decreased in the affected eyes but increased in the contralateral healthy eyes. The systolic peak velocity(CRAmax) of the CRA was significantly reduced in both the affected and contralateral healthy eyes compared to controls. Correlation analysis revealed significant positive correlations between various OA and CRA flow parameters(e.g.,,OAmax,OAPI,CRAmax,CRAPI,in the healthy eye and their corresponding affected eyes. Conversely, the central retinal artery pulsatility index(CRAPI) in healthy eyes was negatively correlated with the CRA minimum velocity(CRAmin) in affected eyes. Furthermore, in the contralateral healthy eye,CRAmax showed a positive correlation with the time from symptom onset to examination.</p><p><strong>Conclusion: </strong>Blood flow in the contralateral healthy eyes of patients is altered and showed significant correlations with the hemodynamic parameters of the affected eyes, suggesting that these so-called \"healthy\" eyes may be affected by a CRAO event and could potentially have pre-existing subclinical abnormalities.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunctive hyperbaric oxygen therapy in high-risk oculoplastic reconstructions requiring graft-based surgery: a retrospective case series.","authors":"Ismail Uyanik, Husna Topcu, Mehmet Goksel Ulas, Fatma Poslu Karademir, Ayse Cetin Efe, Kubra Serefoglu Cabuk","doi":"10.1007/s10792-026-04286-2","DOIUrl":"10.1007/s10792-026-04286-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the postoperative healing course and clinical outcomes of high-risk oculoplastic reconstructions requiring graft-based surgery, in which adjunctive hyperbaric oxygen therapy (HBOT) was used to support wound healing.</p><p><strong>Methods: </strong>This retrospective case series included 11 patients who underwent oculoplastic surgery with graft-based reconstruction and were considered at high risk for delayed healing and/or tissue compromise. Indications for surgery were orbital implant (sphere) exposure repair (n = 5), cicatricial entropion (n = 1), necrotizing scleritis (n = 1), tissue loss following trauma (n = 1), wound dehiscence and infection after lower eyelid blepharoplasty (n = 1), orbital cellulitis following endophthalmitis and evisceration after cataract surgery (n = 1), and delayed wound healing after dermolipoma excision (n = 1). All patients received graft-based surgical management with adjunctive HBOT. Demographic data, culture results, number of HBOT sessions, and recovery time were analyzed. Patients were evaluated according to HBOT exposure (10 vs. 20 sessions).</p><p><strong>Results: </strong>All patients underwent graft-supported surgical repair in the setting of anticipated difficult healing. Culture growth was detected in 5 patients. Clinical stabilization and wound closure were achieved without the need for additional major reconstructive procedures in most cases. Patients receiving 20 HBOT sessions had a longer observed mean recovery time compared with those receiving 10 sessions (82.6 vs. 40.9 days; p = 0.032).</p><p><strong>Conclusion: </strong>In a heterogeneous cohort of high-risk oculoplastic reconstructions requiring grafting-including orbital implant exposure repair and complex inflammatory, infectious, or traumatic etiologies-adjunctive HBOT was used as a supportive modality and was associated with acceptable healing outcomes. The longer recovery observed with extended (20-session) HBOT courses likely reflects greater baseline disease severity rather than a reduced treatment effect. Given the retrospective design and clinical heterogeneity, further studies are needed to clarify patient selection criteria and define optimal HBOT protocols in oculoplastic reconstruction.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal topographic changes after upper eyelid blepharoplasty prior to cataract surgery.","authors":"Kleopatra Varna-Tigka, Sophia Göhring, Myriam Böhm, Yaroslava Wenner, Thomas Kohnen","doi":"10.1007/s10792-026-04285-3","DOIUrl":"https://doi.org/10.1007/s10792-026-04285-3","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effect of upper eyelid blepharoplasty (UEB) on corneal topography in cataract patients using Scheimpflug technology.</p><p><strong>Methods: </strong>This prospective single-center, longitudinal study included 88 eyes of 45 patients undergoing UEB for dermatochalasis prior to cataract surgery. Scheimpflug imaging (Pentacam®AXL, Wetzlar), was performed preoperatively and at two weeks and three months postoperatively. The primary outcome was change in corneal astigmatism, assessed as the cylindrical component of total corneal refractive power (TCRP). Secondary outcomes included K1, K2, Kmax, Km, astigmatism axis and anterior chamber depth (ACD), front and back Keratometry (FK, BK).</p><p><strong>Results: </strong>The mean age of 67.0 ± 8.7 years; 67% of patients were female (n = 30) and 33% male (n = 15). At three-months, statistically significant changes were observed in cylindrical TCRP (P = 0.010), K1 (P = 0.023), and ACD (P = 0.007). Additionally, FK2 showed a statistically significant change at 2 weeks (P = 0.021) but not at three-months. F-KMax and BKm were not significantly changed at 2 weeks, but showed statistically significant changes at three-months follow-up (P = 0.043 and P = 0.010 respectively).</p><p><strong>Conclusion: </strong>UEB was associated with minor changes in selected corneal topographic parameters and ACD. Although some changes reached statistical significance, their clinical relevance was not established. Repeat corneal measurements after UEB may be considered before cataract or refractive surgery when precise refractive outcomes are intended. These findings do not establish a specific three-month waiting period or demonstrate an effect on intraocular lens (IOL) power calculations or final refractive outcomes.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in cataract management: current status and future perspectives.","authors":"Zizhuo Zhao, Manlu Huang","doi":"10.1007/s10792-026-04283-5","DOIUrl":"10.1007/s10792-026-04283-5","url":null,"abstract":"<p><strong>Purpose: </strong>To summarize recent advances in artificial intelligence (AI) applications across the entire cataract management pathway and to discuss current challenges and future directions.</p><p><strong>Methods: </strong>We conducted a narrative mini review of studies published since 2021 on AI applications in cataract diagnosis and screening, intraocular lens (IOL) power calculation, intraoperative guidance, and postoperative management, with emphasis on deep learning and emerging technologies.</p><p><strong>Results: </strong>AI models have achieved expert-level performance in automated cataract detection and grading from slit-lamp images, with pooled AUC values approaching 0.99 in meta-analyses. AI-based IOL power calculation formulas have shown superior accuracy compared with traditional formulas, especially in challenging cases such as highly myopic eyes. Intraoperatively, AI systems can recognize surgical phases and track instruments with high accuracy, supporting surgical training and quality assessment. Postoperatively, multimodal AI models integrating imaging and clinical data have improved the prediction of visual outcomes and complications. Emerging technologies, including large language models, portable smartphone-based screening devices, and multimodal prediction models, represent promising new directions, although challenges related to data generalizability, algorithm interpretability, and clinical translation remain to be addressed.</p><p><strong>Conclusion: </strong>AI has the potential to significantly improve the efficiency, accuracy, and accessibility of cataract care, but should serve as an assistive tool rather than a replacement for clinical judgment.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk stratification of visual field progression in optic disc drusen with and without glaucoma.","authors":"Rohit Y Reddy, Rongrui Liu, Wesam S Shalaby, Sagar J Shah, Kartik Kumar, Binod Acharya, Qiang Zhang, Joel S Schuman, Jonathan S Myers, Ping Huang","doi":"10.1007/s10792-026-04274-6","DOIUrl":"10.1007/s10792-026-04274-6","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the visual field (VF) progression in patients with optic disc drusen (ODD) with or without glaucoma and identify factors associated with rapid deterioration.</p><p><strong>Methods: </strong>In this single-center retrospective cohort, adult patients with ODD, ≥ 12 months of follow-up, and ≥ 3 reliable standard automated perimetry tests were included. VF progression was quantified as the VF mean deviation (MD) slope (dB/year) using linear mixed-effects modeling. Eyes were categorized as slow progression (MD slope > - 0.5 dB/year) or moderate-fast progression (MD ≤ - 0.5 dB/year). Baseline RNFL thickness and VF MD, Visual acuity, intraocular pressure (IOP), glaucoma diagnosis, and number of IOP-lowering medications (NOM) were extracted from the medical record. Associations with moderate-fast progression were evaluated using logistic regression.</p><p><strong>Results: </strong>A total of 139 eyes from 84 patients were included (mean follow-up 57.4 ± 42.6 months; mean 4.9 perimetry tests/eye). Glaucoma was diagnosed in 83/139 eyes (59.7%). Overall, 91/139 eyes (65.5%) demonstrated VF deterioration (MD slope < 0 dB/year), more frequently in glaucoma-labeled eyes than no-glaucoma eyes (64/83 [77.1%] vs. 27/56 [48.2%]; p < 0.001). Moderate-fast progression occurred in 32/139 eyes (23.0%) and did not differ significantly by glaucoma status (28.9% vs. 14.3%, p = 0.064). In multivariable modeling, higher mean NOM was associated with higher odds of moderate-fast progression (adjusted odds ratio 2.41; 95% CI 1.06-5.45; p = 0.034), whereas glaucoma diagnosis and mean IOP were not independently associated. Severity-stratified analyses showed higher moderate-fast progression with baseline VF MD ≤ -6 dB (34.9% vs. 13.2%, p = 0.004) and RNFL < 80 µm (36.4% vs. 7.0%, p < 0.001).</p><p><strong>Conclusions: </strong>In eyes with ODD, thinner RNFL and worse VF MD at baseline are associated with a higher risk of moderate-fast VF decline, supporting risk-stratified monitoring regardless of glaucoma label or IOP.</p>","PeriodicalId":14473,"journal":{"name":"International Ophthalmology","volume":"46 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}