国际医药卫生导报最新文献

{"title":"Comparative study of brain function tests between patients with schizophrenia and normal controls","authors":"L. Bai, H. Gao, Yan Wang, Zhao Zhao, Rui-li Wang, Feng Guo, Yuxiang Jiao","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.002","url":null,"abstract":"Objective To investigate differences in brain function tests between patients with schizophrenia and normal controls.Methods 80 patients who met diagnostic criteria for schizophrenia of International Classification of Diseases (10th edition) received brain function tests,for the same period 52 cases of normal control also received brain function tests.Test results were compared to analyze differences in brain neurotransmitters.Results There were statistically significant differences in GABA and Glu neurotransmitters power between schizophrenia group and normal control group (t =-1.991,P =0.049; t =-2.228,P =0.028).There was statistically significant difference in glutamate neurotransmitter relative power between two groups (t =-2.115,P =0.036).There was statistically significant difference in neurotransmitters total power between two groups (t =-2.631,P =0.010).Conclusion Glutamate neurotransmitter power,relative neurotransmitters power and total neurotransmitters power in schizophrenia group were higher than those in normal control group,which suggested abnormal brain neurotransmitters function in patients with schizophrenia. \u0000 \u0000Key words: \u0000Schizophrenia;  Normal control group;  Brain function tests","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3667-3670"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fiber bronchoscope in treatment of elderly patients with hypostatic pneumonia","authors":"Jinhua Huang, Jiaowu Li, Ying Chen, Qun-jiu Lin","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.022","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.022","url":null,"abstract":"Objective To explore the clinical value of fiber bronchoscope in the treatment of elderly patients with hypostatic pneumonia.Methods 100 elderly patients with hypostatic pneumonia were selected from the Department of Respiratory Medicine at Lecong Hospital of Shunde,Foshan from May,2012 to May,2014.According to different treatment plans,the patients were divided into a treatment group(n=50)and a control group(n=50).In addition of routine treatment,the treatment group accepted sputum aspiration and lavage with bronchofibroscope; the specimens were sampled via protected specimen brush (PSB) or lavage for bacterial culture.The control group received routine treatment; sputum specimens were sampled routinely for bacterial culture.Antibiotics were used and adjusted according to the results of the bacterial culture and the drug sensitive test was carried out in both groups.The therapeutic effect,mortality,results of bacterial culture,hospital stays,and adverse effects of the treatment with fiber bronchoscope were observed.Results The total effective rate and the mortality were 84％ and 8％ in the treatment group and were 64％ and 28％ in the control group,with statistical differences(P ＜ 0.05).88％ patients of the treatment group and 44％ of the control group were positive in bacterial culture.82.0％ patients of the treatment group and 86.4％ of the matched group were positive in Gram negative pathogenic bacteria.After the treatment,the bacterial negative rate was 86.4％ in the treatment group and was 45.5％ in the control group,with a statistical difference(P ＜ 0.05).The mean time of hospital stay was (18.42 ± 4.77) days in the treatment group and was (23.06 ± 6.08) days in the control group,with a statistical difference(P ＜ 0.05).No severe adverse reactions occurred during the treatment with the fiber bronchoscope.Conclusions Fiber bronchoscope in the treatment of elderly patients with hypostatic pneumonia is effective and safe and can reduce the mortality,increase the detectable rate of pathogenic bacteria,shorten the hospital stay,and reduce the hospitalization expense.It is worth being clinically generalized. \u0000 \u0000Key words: \u0000Fiber bronchoscope;  Sputum aspiration and lavage;  Bacterial culture;  Elderly patients with hypostatic pneumonia;  Treatment","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3738-3742"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"不同时间给予布托啡诺预防瑞芬太尼麻醉后早期急性疼痛的效果分析","authors":"王瑞国","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.032","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.032","url":null,"abstract":"目的 分析不同时间给予布托啡诺预防瑞芬太尼麻醉后早期急性疼痛的效果.方法 按就诊顺序号将我院2013年1月至2014年6月收治的于全身麻醉下行腹腔镜手术的96例患者分为A组(手术结束前静脉注射布托啡诺0.02 mg/kg)、B组(手术结束时静脉注射布托啡诺0.02mg/kg)和C组(于气管拔管后静脉注射布托啡诺0.02 mg/kg),每组32例.比较三组患者的VAS评分和镇痛效果.结果 A组术后10 min、20 min和30 min的VAS评分分别为(3.63±0.36)分、(3.95±0.53)分和(4.06±0.41)分,B组分别为(3.19±0.33)分、(2.23±0.59)分和(2.16±0.52)分,C组分别为(3.69±0.38)分、(4.60±0.56)分和(4.35±0.54)分,其中B组各时点的VAS评分明显低于其他两组,差异均具有统计学意义(P＜0.05).A组术后镇痛有效17例,无效15例,镇痛有效率为53.13％;B组术后镇痛有效26例,无效6例,镇痛有效率为81.25％;C组术后镇痛有效15例,无效17例,镇痛有效率为46.88％;B组镇痛有效率明显高于其他两组,差异均具有统计学意义(P＜0.05).结论 于手术结束时给予布托啡诺预防瑞芬太尼麻醉后早期急性疼痛的效果优于其他时点,临床上可加以借鉴和推广。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3769-3771"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"三代喉罩与气管插管在全麻诱导期对循环和BIS的影响","authors":"宋文琴, 陈林穆, 慈爱字","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.025","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.025","url":null,"abstract":"目的 比较气管插管和三代喉罩(PLMA)在全麻诱导期对HR、SBP和BIS的影响,评价三代喉罩在全麻术中的应用价值.方法 将120例腹腔镜胆囊切除全麻术患者120例,按照患者入院先后顺序分为观察组和对照组,各60例.对照组采用气管插管术,观察组采用置入三代喉罩法.记录患者诱导前(T1)、诱导后(T2)、插管(或置入喉罩)后(T3)、插管(或置入喉罩)后1min(T4)、插管(或置入喉罩)后3 min(T5)的SBP、BIS和HR,评价三代喉罩在全麻术中的价值.结果 观察组T3、T4时点的BIS分别为(48±7)、(47±9),显著低于对照组(P＜0.05).观察组T3、T4、T5时点的SBP分别为(106±10) mmHg、(105±9)mmHg和(104±9) mmHg,显著低于对照组(P＜0.05).观察组T3、T4、T5时刻的HR分别为(68±9)次/min、(68±7)次/min、(66±7)次/min,与对照组比较,差异有统计学意义(P＜0.05).结论 与气管插管术相比,在全麻术中使用三代喉罩可以有效保持患者循环系统稳定,避免中枢神经兴奋性提高,值得在临床中推广应用。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3749-3751"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of thymidine kinase 1 in serum of patients with breast carcinoma and its clinical significance","authors":"Juan Huang, X. Tan, Yi-yao Tang","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.018","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.018","url":null,"abstract":"Objective To investigate the influence of surgery on the level of thymidine kinase 1(TK1) in the serum of patients with breast carcinoma detecting its serum level.Methods Sensitive chemiluminescence dot-blot assay was used to detect the serum TK1 levels of 33 healthy women and 65patients with breast carcinoma.The clinical implications were also analyzed.The serum TK1 levels of 38 patients with breast carcinoma were compared between before and after the operatiou.Results The serum TK1 level was higher in the patients with breast carcinoma than in the healthy women,with a statistical difference(P ＜ 0.01).Serum TK1 level didn' t correlated with age and pathologic types but correlated with clinical stage; the serum TK1 level was higher in stage Ⅳ patients than in stage Ⅲ,in stage Ⅲ than in stage Ⅱ,and in stage Ⅱ than in stage Ⅰ (P ＜ 0.01,P ＜ 0.05).The level of serum TK1 was obviously reduced in patients with breast carcinoma after the operation(P ＜ 0.01).Conclusions The serum TK1 levels in patients with breast carcinoma are higher; it could be an indicator assessing the disease status,therapeutic effect,and the prognosis of breast carcinoma. \u0000 \u0000Key words: \u0000Thymidine kinase 1;  Breast carcinoma;  Operation","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3726-3728"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"巨大胃肠外胃肠间质瘤2例报告及诊疗共识","authors":"李传宝, 隋国龙, 刘船","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.031","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.031","url":null,"abstract":"胃肠间质瘤(Gastrointestinal stromal Tumor,GIST)是胃肠道最常见的间叶源性肿瘤,主要发生在胃、小肠、结直肠、阑尾及食道,也有极少数起源于胃肠道外,但临床病理表现、免疫组化表型及分子生物学特征类似于胃肠间质瘤,称为胃肠外胃肠间质瘤(Extra-gastrointestinal stromal tumor,EGIST),占胃肠间质瘤的5％左右,主要位于网膜、肠系膜及腹膜后.我科收治两例典型的巨大胃肠外胃肠间质瘤,现总结其诊疗过程,并结合文献资料,总结临床诊疗共识如下. 关键词：巨大胃肠外胃肠间质瘤;诊疗","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3767-3769"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hazard control effect of occupation disease at a float glass factory","authors":"Jinquan Chen, Qibing Lu, F. Huang, Jianming Tan, Shao-wei Wu, Yanfen Xu","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.014","url":null,"abstract":"Objective To explore the hazard control effect of occupation disease at a float glass factory.Methods Occupational hygienic investigation,occupational hazards and protecting facilities for occupational hazards detection,and occupational health examination were used to evaluate the control effect of occupational hazards.Results The major hazard factors causing occupation diseases were dust,noise,high temperature,chemical toxicants (ammonia,carbon monoxide,carbon dioxide,nitrogen dioxide,sulfur dioxide,two tin oxide,and non-methane total hydrocarbon),and electromagnetic field.Free silica dust in 13 copies (SiO2) of contents was average (34.51 ± 27.38)％ (2.65％ ～ 71.74％).Total dust concentration was detected at 41 points,with a qualified rate of 95.12％ (39/41).The intensity of noise was detected at 32 points,with a qualified rate of 93.75％ (30/32).Chemical toxicant concentrations were detected at 66 points,with a qualified rate of 100.00％.High temperature test was carried out at 8 points,of which 4 points (50.00％) were over the occupation contact limiting value.The detection results of power frequency electric field strength were all qualified.The face velocity of occupation disease prevention facilities was 0.03 ～ 3.26 m/s.389 people took occupation health examination; no one were suspected with occupation disease,and 3 were found with high temperature or noise operation contraindication.Conclusions The occupation disease harm at chemical toxicants and power frequency electric field is controlled well.The control effect of dust and noise hazards is good.The harm of high temperature control effect is poor.Prevention and control work of high temperature,noise,and dust hazards needs to be enhanced. \u0000 \u0000Key words: \u0000Occupation hazards;  Control effect analysis;  Chemical poisons;  Dust;  Noise","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3708-3712"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of curative effect of three kinds of operation method for varicocele","authors":"Quanming Ding, W. Liang, Gang Wang, Shiwei Feng, Zhongkai Qiu, Guilan Sun, Xingliang Zhao","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.023","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.023","url":null,"abstract":"Objective To evaluate clinical application value and curative effect of laparoscopic,retroperitoneal open operation and microscopical treatment of varicocele.Method 85 cases of varicocele who were treated with three kinds of operation method in our hospital from 2005 to 2013 were randomly selected.Results All patients selected had fast recovery after surgery,without recurrence and atrophy of testis.Sperm quality in 77 patients improved in varying degrees after surgery.Sperm count and activity rate after operation were significantly higher than those before operation,with statistically significant difference (P ＜ 0.01).Postoperative pregnancy rate was 25％.Spermiogenesis function in 8 patients did not improve obviously after surgery,whose preoperative sperm count was ＜ 10 × 106/ml.Conclusions Regardless of the degree of varicocele,once bad semen quality is found,and other causes ruled out,operation should be taken as soon as possible.There is no difference between three kinds of operation method for side varicocele,laparoscopic surgery is more appropriate for recurrent and bilateral varicocele. \u0000 \u0000Key words: \u0000Varicocele;  Three kinds of operation method;  Male infertility","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3743-3746"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"肥厚性硬脑膜炎26例临床分析","authors":"胡运新, 包则岩, 王展航, 曾昭龙","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.026","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.026","url":null,"abstract":"目的 探讨肥厚性硬脑膜炎的临床表现、影像学特点及治疗方法与转归,指导临床诊治.方法 通过对26例肥厚性硬脑膜炎患者的病因、临床表现、脑脊液检查、影像学特点进行总结和分析,总结其特点和规律.结果 26例患者均以头痛为首发症状,颅神经损害19例.头颅MRI检查:16例未见明显异常,10例有异常发现,病变处硬脑膜表现为T1WI呈等或稍低信号、T2WI呈低信号;26例MR增强扫描均可见病变处硬脑膜呈明显强化.脑脊液检查中有6例压力轻度升高,12例白细胞升高(10×106/L ～ 320×106/L),17例蛋白升高(9.5～ 1.0g/L).原发性肥厚性硬脑膜炎患者均给予甲基强的松龙冲击治疗后以强的松维持治疗,继发性肥厚性硬脑膜炎患者根据其发病原因的不同,分别给予第三代头孢抗感染、更昔洛韦抗病毒或抗结核治疗,同时配合小剂量地塞米松,效果满意.治疗1个月后,头痛消失14例,减轻12例,颅神经麻痹痊愈10例,好转9例.随访半年,复发4例,死亡1例.结论 肥厚性硬脑膜炎病因复杂,根据患者的临床表现、头颅MRI+增强、脑脊液检查可明确诊断,原发性肥厚性硬脑膜炎单纯应用激素有效,继发性肥厚性硬脑膜炎则以病因治疗为主,可配合小剂量激素。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"16 1","pages":"3751-3754"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"农村妇女乳腺癌早期健康教育干预效果分析","authors":"林顺欢, 刘淳, 蔡彦敏","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.24.047","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.24.047","url":null,"abstract":"目的 探讨在农村妇女乳腺癌患者中实行早期健康教育的干预效果.方法 将100例农村妇女随机分为观察组(n=50例)和对照组(门=50例).对照组妇女仅接受社区的常规宣传教育,观察组妇女接受乳腺癌相关的健康教育.统计100例患者的乳腺筛查结果,通过问卷调查方式了解两组对乳腺癌相关知识的掌握程度.结果 对100例农村妇女进行了乳腺癌的筛查工作,其中乳腺增生20例(20.00％),乳腺良性肿瘤3例(3.00％).干预后观察组的平均分数明显高于对照组(p＜0.05).结论 在农村妇女中开展乳腺癌的健康教育工作,有助于提高她们对乳腺癌知识的掌握程度,有助于早期防治工作的开展。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3808-3810"},"PeriodicalIF":0.0,"publicationDate":"2014-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}