International Journal of Psychiatry in Clinical Practice最新文献

{"title":"Relation between serum oxytocin levels and impulsivity in patients under treatment for alcohol use disorder.","authors":"Aylin Çıklacoşkun, Tayfun Turan, Saliha Özsoy, Eser Kılıç, Ali Emre Köse","doi":"10.1080/13651501.2026.2722063","DOIUrl":"https://doi.org/10.1080/13651501.2026.2722063","url":null,"abstract":"<p><strong>Objective: </strong>Due to shared oxytocin pathways in impulsivity and alcohol use disorder (AUD), impulsivity is thought to increase susceptibility to AUD through the oxytocin system. This study investigated this relationship in patients under treatment for alcohol use disorder.</p><p><strong>Method: </strong>The study included 32 AUD patients and 34 healthy controls. First day of alcohol withdrawal, patients were assessed with the Clinical Institute Withdrawal Assessment for Alcohol-Revised (CIWA-Ar) and the Hamilton Depression Rating Scale (HAM-D). On day 14, all these assessments were repeated along with the Michigan alcoholism screening test (MAST) and Barratt Impulsiveness Scale version 11 (BIS-11) then blood samples were taken to measure oxytocin levels. Only the HAM-D and BIS-11 scales were used in the control group, and blood samples were collected for oxytocin measurement.</p><p><strong>Results: </strong>The patient group had significantly lower oxytocin levels. The BIS-11 scores, including all subscales, were significantly higher in the patient group. A significant negative correlation was found between oxytocin levels and both the total BIS-11 score and the motor impulsivity subscale score in the patient group.</p><p><strong>Conclusion: </strong>These findings suggest that impulsivity may increase susceptibility to AUD through the oxytocin system. To better understand this relationship further research is needed.</p><p><strong>Key points: </strong>Serum oxytocin levels in the patient group were statistically significantly lower.All of the BIS-11 subscale scores and total BIS-11 score were statistically significantly higher in the patient group.A statistically significant negative correlation was found between the serum oxytocin levels, and the total BIS-11 score and motor impulsivity subscale score in the patient group.The results of this study are valuable in elucidating the role of impulsivity and oxytocin in AUD.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-7"},"PeriodicalIF":2.3,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gaps in suicide-related clinical competence across European psychiatric training: a multicountry study of trainees and early career psychiatrists.","authors":"Giulio Longo, Filipa Santos Martins, Daniele Cavaleri, Marta Gostiljac, Etienne Karl Duranté, Iliya Petkov Peyneshki, Marija Purić, Serkan Turan, Siirnaz Kukurt, Onochie Emeka, Steve Sammut Alessi, Nedim Huskić, Nuria Laherran-Cantera, Peter Bauer, Anna C Mavromanoli, Martijn Godschalk, Sara Medved, Laura Orsolini, Umberto Volpe","doi":"10.1080/13651501.2026.2715438","DOIUrl":"https://doi.org/10.1080/13651501.2026.2715438","url":null,"abstract":"<p><strong>Objective: </strong>Suicide prevention is a core competence in psychiatric practice, limited data are available on suicide-related knowledge among European psychiatric trainees and early career psychiatrists (ECPs). The study aimed to examine variation in knowledge and perceived suicide-related competence.</p><p><strong>Methods: </strong>An online survey was conducted in a multicountry convenience sample of psychiatric trainees and ECPs across Europe from May 2024 to October 2025. Participants completed a questionnaire on exposure to patient suicide (PS) and related reactions/support, the Suicide Knowledge and Skills Questionnaire, and the Maslach Burnout Inventory.</p><p><strong>Results: </strong>A total of 259 psychiatric trainees and ECPs from 36 countries completed the survey. The mean percentage of correct responses in the suicide knowledge section of the SKSQ was 76.7%. Participants exposed to at least one PS showed higher knowledge scores than those not exposed. In regression models, suicide knowledge was positively associated with personal accomplishment, exposure to PS, and comfort in asking direct suicide-related questions.</p><p><strong>Conclusions: </strong>Findings reveal variability in suicide-related competence across European psychiatric training, suggesting the need to strengthen structured, skills-based suicide prevention training, regular supervision, and post-event support pathways. Such training should not rely on reactive learning after adverse clinical events, but should address both technical, emotional and ethical competencies of psychiatric practice.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-9"},"PeriodicalIF":2.3,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethical considerations for artificial intelligence use in clinical practice: a comparative study of EU member state frameworks.","authors":"Maksymilian Aleksander Brzezicki, Przemysław Temistokles Zakowicz","doi":"10.1080/13651501.2026.2718248","DOIUrl":"https://doi.org/10.1080/13651501.2026.2718248","url":null,"abstract":"<p><strong>Objective: </strong>Regulatory frameworks governing artificial intelligence (AI) in medical practice vary widely across European Union (EU) member states. We assessed the extent to which national medical bodies' codes of conduct address the clinical use of AI.</p><p><strong>Methods: </strong>Codes of conduct issued by national medical regulatory bodies in EU member states were analysed and rated for AI-specific content using a four-point scoring system.</p><p><strong>Results: </strong>Six countries (Belgium, France, Germany, Lithuania, Poland and Spain) had established AI-specific guidance within their medical ethical frameworks, with scores of 3 to 4; the remaining member states had none. France and Belgium showed the most progressive approaches, emphasising innovation while maintaining ethical standards, whereas Germany and Poland were more conservative, imposing stringent requirements for AI deployment in clinical settings. EU-wide instruments such as the AI Act and the High-Level Expert Group (HLEG) guidelines provide overarching frameworks but do not address the codes of medical practice that govern day-to-day clinical decision-making in member states.</p><p><strong>Conclusion: </strong>The heterogeneous landscape reflects the challenge of balancing technological advancement with patient safety. Harmonised national ethical guidelines and closer collaboration between medical regulatory bodies are needed to support responsible AI adoption while preserving ethical practice across the EU.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-9"},"PeriodicalIF":2.3,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of deep brain stimulation for psychiatric and neurological indications on a meta-analytic level.","authors":"Victoria Froschauer, Johan Saelens, Anna Gramser, Julian Thewes, Marco Treven, Christof Brücke, Klaus Novak, Rupert Lanzenberger, Christoph Kraus","doi":"10.1080/13651501.2026.2710644","DOIUrl":"https://doi.org/10.1080/13651501.2026.2710644","url":null,"abstract":"<p><strong>Objective: </strong>Deep brain stimulation (DBS) is used to treat movement disorders, but it is rarely used for psychiatric indications. We aim to demonstrate clinical effects in randomised-controlled trials (RCTs) of DBS for clinically used neurological and psychiatric indications.</p><p><strong>Methods: </strong>We searched databases for RCTs conducting blinded comparisons of active to sham DBS for: obsessive-compulsive disorder (OCD), major depressive disorder (MDD), Gilles-de-la-Tourette syndrome (GTS), Parkinson's Disease (PD), essential tremor (ET), dystonia (DYT) and epilepsy (ED). We compared 28 studies with a meta-analytic approach of the indication-specific scores.</p><p><strong>Results: </strong>For psychiatric indications, we found a standardised mean difference (SMD) of -0.22 for MDD (<i>p</i> = .204), a SMD of -0.72 for OCD (<i>p</i> = .004) and a SMD of -1.22 for GTS (<i>p</i> = .014). For neurological indications, we found a SMD of 0.74 in PD (<i>p</i> < .001), a SMD of -1.42 in ET (<i>p</i> = .0003), a SMD of -0.71 for DYT (<i>p</i> = .006) and a SMD of -0.09 for ED (<i>p</i> = .790).</p><p><strong>Conclusions: </strong>Effect sizes in clinical trials were highest in ET in neurology and in GTS in psychiatry. These results underscore that wider clinical use in the psychiatric indications OCD and GTS is justifiable.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-14"},"PeriodicalIF":2.3,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148669487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in irritability levels during different antidepressant treatments: a naturalistic follow-up study.","authors":"Kürşad Çifteci, Hakan Yılmaz, Betül Nas, Hasan Turan Karatepe, Rümeysa Yeni Elbay, Ebru Turgal, Mehmet Emrah Karadere","doi":"10.1080/13651501.2026.2706181","DOIUrl":"https://doi.org/10.1080/13651501.2026.2706181","url":null,"abstract":"<p><strong>Background and objectives: </strong>Irritability, characterised by heightened negative affect and emotional dysregulation, is clinically significant but understudied during antidepressant treatment. This study examined changes in irritability among patients with depression and anxiety disorders starting antidepressants. It also explored whether these changes were independent of improvements in depression and anxiety and if baseline irritability predicted outcomes.</p><p><strong>Methods: </strong>Eighty adults with depression or anxiety were followed for two months. Assessments at baseline, 2, 4 and 8 weeks included the Brief Irritability Test, Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale. Statistical analyses assessed irritability changes and their association with outcomes.</p><p><strong>Results: </strong>Irritability significantly decreased over time, independent of reductions in depression and anxiety (<i>p</i> < 0.001). Baseline irritability predicted depression (<i>β</i> = 0.185, <i>p</i> = 0.009) and anxiety (<i>β</i> = 0.195, <i>p</i> = 0.019) scores at two months. Irritability reductions did not differ significantly between selective serotonin reuptake inhibitors (<i>p</i> = 0.237).</p><p><strong>Conclusions: </strong>Irritability decreases independently of depressive and anxiety symptom improvements during antidepressant treatment. Baseline irritability predicts depression and anxiety levels at two months. Addressing irritability may enhance treatment and warrants further investigation.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-6"},"PeriodicalIF":2.3,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic drug monitoring of sertraline and symptom change in major depressive disorder: a naturalistic outpatient study.","authors":"Maria Luca, Alessandro Serretti, Antonina Luca, Filippo Drago, Ignazio Maniscalco, Xenia Hart, Georgios Schoretsanitis, Raffaele Ferri, Andreas Conca, Vincenzo Florio","doi":"10.1080/13651501.2026.2706177","DOIUrl":"https://doi.org/10.1080/13651501.2026.2706177","url":null,"abstract":"<p><strong>Background: </strong>Therapeutic drug monitoring (TDM) has been proposed to address interindividual variability in antidepressant exposure and to support concentration-response informed dosing. However, evidence linking sertraline serum concentrations to clinical response remains inconsistent. This study examined whether steady-state serum concentrations of sertraline (SCS) are associated with symptom improvement in major depressive disorder (MDD).</p><p><strong>Methods: </strong>In this study, adult outpatients with MDD receiving sertraline monotherapy were assessed at baseline (<i>t</i>0), 1 month (<i>t</i>1) and 3 months (<i>t</i>2) using the 21-item Hamilton Depression Rating Scale (HAMD-21). Morning steady-state SCS were quantified by LC-MS/MS. Regression models tested associations between SCS and percentage symptom change (delta) at <i>t</i>1 and <i>t</i>2. An exploratory analysis evaluated the association between baseline HAMD-21 severity and delta at 3 months.</p><p><strong>Results: </strong>The sample included 52 patients. No association was observed between SCS and symptom change. In the exploratory analysis, baseline HAMD-21 scores were associated with delta at 3 months.</p><p><strong>Conclusions: </strong>In our study, steady-state sertraline concentrations were not associated with symptom improvement over 3 months in linear models. Baseline symptom severity emerged as a key determinant of change, suggesting that limited baseline severity in part of the sample may have reduced sensitivity to detect concentration-response relationships.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-4"},"PeriodicalIF":2.3,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148548952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is asked, but not heard? Assessing characteristics of youth with severe and enduring mental health problems during diagnostics in child-and-adolescent psychiatry.","authors":"Chanel H Bansema, Laura A Nooteboom, Lian Nijland, Rianne de Soet, Branko M van Hulst, Robert R J M Vermeiren","doi":"10.1080/13651501.2026.2702937","DOIUrl":"https://doi.org/10.1080/13651501.2026.2702937","url":null,"abstract":"<p><strong>Objective: </strong>Severe and enduring mental health problems (SEMHP) in youth often fall outside traditional diagnostic classifications, which may lead to insufficient assessment of these youth's characteristics in classification-based psychiatry practice. Therefore, the objective of this study is to explore how current diagnostic practices in child-and-adolescent psychiatry address specific characteristics of youth with SEMHP by mapping the diagnostic process. Moreover, we aim to identify facilitators and barriers to effective assessment of specific SEMHP-characteristics by analysing stakeholders' perspectives.</p><p><strong>Methods: </strong>The exploration involved: 1) mapping the diagnostic processes (e.g., steps, tools) used in a CAP facility in the Netherlands by conducting semi-structured preparatory interviews with eight professionals in CAP in July-September 2023, and 2) qualitative analysis of stakeholder experiences to understand how SEMHP-characteristics are assessed, and what factors facilitate or hinder adequate assessment of these SEMHP-specific characteristics through focus groups. Separate focus groups with ten clinicians (<i>n = 5, n = 5),</i> eight youth (<i>n = 5, n = 3</i>) and five caregivers (<i>n</i> =<i> 5</i>) were conducted, using a semi-structured topic guide in December 2023 till May 2024. Data was analysed using reflexive thematic analysis to unravel barriers and facilitators in SEMHP-assessment.</p><p><strong>Results: </strong>While all examined SEMHP-characteristics in this study were addressed in the diagnostic process, still participants reported feeling unseen or misunderstood during the assessments. Participants identified factors that hindered and facilitated the diagnostic assessment including distrust in systems, masking behaviour of youth, lack of time and generational differences in recent societal developments such as social media.</p><p><strong>Conclusion: </strong>Our study highlights stakeholder-identified barriers, revealing a shared perception of disconnect within the diagnostic process. This disconnect refers to a mismatch between clinical assessments and the lived experiences of youth and caregivers, in which they feel unheard, share less and experience being overlooked. Overcoming barriers requires viewing diagnostics as a relational process, where, in addition to gathering information, the focus in on building a therapeutic relationship, prioritising youth's story and emphasising individual understanding.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-11"},"PeriodicalIF":2.3,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148548935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Statement: Psychometric properties of the Female Sexual Distress Scale-Revised among a sample of non-clinical Iranian women.","authors":"","doi":"10.1080/13651501.2026.2693352","DOIUrl":"https://doi.org/10.1080/13651501.2026.2693352","url":null,"abstract":"","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1"},"PeriodicalIF":2.3,"publicationDate":"2026-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological and social rhythm differences, daily melatonin secretion and psychiatric symptoms in healthy adults.","authors":"Ümran Eğilmez, Fatih Ekici, Ali Kandeğer, Yavuz Selvi","doi":"10.1080/13651501.2026.2695468","DOIUrl":"https://doi.org/10.1080/13651501.2026.2695468","url":null,"abstract":"<p><strong>Objective: </strong>To examine associations of chronotype and social jetlag (SJL) with psychiatric symptoms and melatonin secretion in healthy adults.</p><p><strong>Methods: </strong>In this cross-sectional study, 95 relatively young, university-affiliated students and staff completed the MEQ, SCL-90-R, MCTQ and a one-week sleep diary. SJL was defined as the workday-free-day difference in midsleep. Overnight workday urinary 6-sulfatoxymelatonin (6-SMT) was assayed by ELISA and indexed to creatinine.</p><p><strong>Results: </strong>Evening chronotypes had longer SJL than intermediate and morning chronotypes (<i>F</i> = 16.70, <i>p</i> < .001). Higher MEQ scores were associated with shorter SJL and earlier midsleep (<i>r</i> = -0.54 to -0.66, all <i>p</i> < .001). Total SCL-90-R scores did not differ across chronotypes (<i>p</i> = .367), whereas obsessive-compulsive symptoms were higher in the evening group (<i>p</i> = .027). Urinary 6-SMT/creatinine did not differ by chronotype (<i>F</i> = 0.823, <i>p</i> = .442) or relate to SJL; BMI correlated inversely with 6-SMT (<i>r</i> = -0.21, <i>p</i> = .043). Lower MEQ scores independently predicted longer SJL (<i>B</i> = -2.82, <i>β</i> = -0.54, <i>p</i> < .001).</p><p><strong>Conclusions: </strong>Eveningness was associated with greater SJL and obsessive-compulsive symptoms, whereas overnight 6-SMT was not linked to chronotype or SJL. The inverse BMI-6-SMT association may suggest metabolic relevance.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-8"},"PeriodicalIF":2.3,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148351902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic utility of pan-immune inflammation value in drug-naïve first-episode psychosis.","authors":"Seda Kiraz, Ezgi Cellat, Bedirhan Şenol, Merve Eltemiz Yıldırım, Erol Göka","doi":"10.1080/13651501.2026.2688109","DOIUrl":"https://doi.org/10.1080/13651501.2026.2688109","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether the pan-immune-inflammation value (PIV), derived from blood parameters, can distinguish first-episode psychosis (FEP) from healthy controls (HCs) and to compare its performance with other indices.</p><p><strong>Methods: </strong>In this retrospective study, 68 drug-naïve patients with FEP and 83 healthy controls were included. Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), C-reactive protein-to-albumin ratio (CAR), and PIV were calculated from complete blood count and biochemistry. Receiver operating characteristic (ROC) analysis identified the optimal PIV cut-off, and its diagnostic value was tested using univariate and multivariate logistic regression.</p><p><strong>Results: </strong>Mean PIV values were 378.10 in the FEP group and 170.07 in HCs, with significantly higher levels in patients (p < 0.001). PIV showed the highest discriminative ability (The area under the ROC curve (AUC) = 0.755 (95% CI: 0.674-0.837)). A cut-off of 170.7 yielded 75.0% sensitivity and 72.3% specificity. Individuals with PIV ≥ 170.7 had increased odds of FEP (univariate OR = 7.83; multivariate OR = 9.31 after adjustment for age and sex; p < 0.001). Other indices were also significant but showed lower AUCs.</p><p><strong>Conclusion: </strong>PIV may outperform traditional inflammation indices in distinguishing drug-naïve FEP patients from HCs and could support risk stratification.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-9"},"PeriodicalIF":2.3,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}