International Journal of Psychiatry in Clinical Practice最新文献_第2页

Real-world outcomes of long-term use of silexan in patients with anxiety disorders: a single-centre experience. 焦虑症患者长期服用西乐葆的实际效果：单中心经验。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-08-18 DOI: 10.1080/13651501.2024.2391301

Sergio Marchevsky

{"title":"Real-world outcomes of long-term use of silexan in patients with anxiety disorders: a single-centre experience.","authors":"Sergio Marchevsky","doi":"10.1080/13651501.2024.2391301","DOIUrl":"https://doi.org/10.1080/13651501.2024.2391301","url":null,"abstract":"Objective: To evaluate the effectiveness and safety of long-term use of silexan in patients with a wide range of anxiety disorders.Methods: A retrospective chart review was conducted on 50 patients diagnosed with various anxiety disorders who were prescribed silexan. The primary outcomes measured included the resolution of anxiety symptoms, changes in Generalized Anxiety Disorder-7 (GAD-7) scores, and Clinical Global Impressions-Improvement (CGI-I) scores. The duration of silexan use and any reported adverse events were also recorded.Results: Silexan effectively resolved anxiety symptoms in 35 patients, with 24 out of 25 patients who received silexan for more than 12 weeks showing significant improvement. Median GAD-7 and CGI-I scores decreased significantly (p<0.001). By the end of the follow-up period, 46% of patients had minimal anxiety and 24% had mild anxiety. No adverse events were reported during the study period.Conclusions: Long-term use of silexan is feasible, safe, and effective in managing a wide range of anxiety disorders in real-world clinical settings.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-4"},"PeriodicalIF":2.9,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141995678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurobiological and psychological factors to depression. 抑郁症的神经生物学和心理学因素。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-08-05 DOI: 10.1080/13651501.2024.2382091

Malini Turner

引用次数: 0

How to treat subsyndromal anxiety disorder - practical recommendations for implementation in primary care. 如何治疗亚综合征焦虑症--在初级保健中实施的实用建议。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-06-22 DOI: 10.1080/13651501.2024.2362131

Daniel Lucas da Conceição Costa, Rodolfo Furlan Damiano, José Ángel Alcalá, Martin Hatzinger, Francisco Mesa, Giampaolo Perna, György Purebl, Péter Torzsa, Věra Vobořilová, Peter Zwanzger, Roger Ho, Borwin Bandelow

{"title":"How to treat subsyndromal anxiety disorder - practical recommendations for implementation in primary care.","authors":"Daniel Lucas da Conceição Costa, Rodolfo Furlan Damiano, José Ángel Alcalá, Martin Hatzinger, Francisco Mesa, Giampaolo Perna, György Purebl, Péter Torzsa, Věra Vobořilová, Peter Zwanzger, Roger Ho, Borwin Bandelow","doi":"10.1080/13651501.2024.2362131","DOIUrl":"https://doi.org/10.1080/13651501.2024.2362131","url":null,"abstract":"Background: Anxiety is a common and disabling condition that significantly impacts quality of life. Subsyndromal anxiety (SSA) refers to anxiety symptoms that do not meet the full diagnostic criteria for an anxiety disorder but pose a risk for developing such disorders. We aimed to provide practical recommendations for the treatment of SSA in primary care settings.Methods: A narrative review was conducted to identify strategies for recognizing and treating patients with SSA.Results: The recommendations for treating SSA include lifestyle modifications such as exercise and stress reduction techniques, psychotherapy, and pharmacological treatments, including natural compounds like the lavender oil extract Silexan. Regular follow-up care is essential to monitor treatment response and address ongoing symptoms. Additionally, the use of the GAD-7 tool is recommended for accurately identifying patients with SSA.Conclusion: Implementing these recommendations in primary care can lead to effective treatment of SSA, preventing the development of more severe anxiety disorders. An integrative approach, combining lifestyle modifications, psychotherapy, and pharmacotherapy, including natural compounds, offers significant benefits for managing anxiety.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141440466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of suicide attempt, suicide ideation and self-harm at diagnosis in adolescents with eating disorders 患有饮食失调症的青少年在确诊时自杀未遂、自杀意念和自残行为的发生率

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-09 DOI: 10.1080/13651501.2024.2337796

Sinem Akgül, Melis Pehlivantürk Kızılkan, Ayşegül Yıldırım, Orhan Derman

引用次数: 0

Effects of seasonality in emergency admissions for mental disorders: two years of clinical experience 精神障碍急诊入院的季节性影响：两年的临床经验

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-08 DOI: 10.1080/13651501.2024.2331481

Thomas Fraccalini, Valerio Ricci, Beatrice Tarozzo, Luciano Cardinale, Giuseppe Primerano, Meraji Kowsaralsadat, Giacomo Piccininni, Adriana Boccuzzi, Giuseppe Maina, Giovanni Volpicelli

引用次数: 0

Suicide ideation and male-female differences in major depressive disorder 自杀意念与重度抑郁障碍的男女差异

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-08 DOI: 10.1080/13651501.2024.2335950

Paolo Olgiati, Basilio Pecorino, Alessandro Serretti

引用次数: 0

Editorial: Embracing continuity and diversity in psychiatric practice 社论：拥抱精神科实践的连续性和多样性

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-03 DOI: 10.1080/13651501.2024.2336822

Pia Baldinger-Melich

引用次数: 0

The relevance of anti-N-methyl-d-aspartate receptor encephalitis for psychiatrists 抗 N-甲基-d-天冬氨酸受体脑炎对精神科医生的意义

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-03-04 DOI: 10.1080/13651501.2024.2323926

Denis Pavăl, Nicoleta Gherghel-Pavăl, Octavia Oana Căpățînă, Adina Stan, Ioana Valentina Micluția

引用次数: 0

Sertraline with desvenlafaxine and sertraline with mirtazapine as treatment initiation in MDD patients with moderate to severe depression and effect on inflammatory markers. 舍曲林联合地文拉法辛、舍曲林联合米氮平治疗中重度抑郁症患者炎症指标的影响

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-03-01 Epub Date: 2023-11-29 DOI: 10.1080/13651501.2023.2287754

Norman Arockiaraj, Rachna Gupta, Rafat Ahmad, Sumita Halder, M S Bhatia

{"title":"Sertraline with desvenlafaxine and sertraline with mirtazapine as treatment initiation in MDD patients with moderate to severe depression and effect on inflammatory markers.","authors":"Norman Arockiaraj, Rachna Gupta, Rafat Ahmad, Sumita Halder, M S Bhatia","doi":"10.1080/13651501.2023.2287754","DOIUrl":"10.1080/13651501.2023.2287754","url":null,"abstract":"Background: This study evaluated the effect of sertraline with desvenlafaxine and sertraline with mirtazapine on HAM-D score and inflammatory markers (IL-6 and TNF-α levels) in major depressive disorder.Methods: Patients (18-60 years) with MDD diagnosed by DSM-V criteria and HAM-D score 18 or more were included (n = 60). Group A patients (n = 30) received sertraline 50 mg/day and desvenlafaxine 50 mg/day. Group B patients (n = 30) received sertraline 50 mg/day and mirtazapine 30 mg/day. All patients were followed up for 8 weeks for the evaluation of clinical efficacy, safety, serum IL-6, and TNF-α levels.Results: Our study showed a comparatively similar and statistically significant (p < 0.05) reduction in HAM-D score in both groups in the 4th and 8th week of the treatment. Both drug combinations significantly (p < 0.05) decreased serum IL-6 and TNF-α after 8 weeks of treatment.Conclusion: The present study suggests that the combination therapy (as treatment initiation) with sertraline and desvenlafaxine, and sertraline with mirtazapine is effective and well tolerated in MDD patients with moderate to severe depression, and their therapeutic efficacy is accompanied by decreased inflammatory markers (serum IL-6 and TNF-α).","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"9-16"},"PeriodicalIF":3.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Depressive symptoms in the entire spectrum of cognitive ageing in Greece: evidence from the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD). 希腊认知老龄化全过程中的抑郁症状：希腊老龄化和饮食纵向调查（HELIAD）提供的证据。

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-03-01 Epub Date: 2023-12-25 DOI: 10.1080/13651501.2023.2296889

Eleni-Zacharoula Eliza Georgiou, Antonios Politis, Mary H Kosmidis, Mary Yannakoulia, Efthimios Dardiotis, Georgios Hadjigeorgiou, Paraskevi Sakka, Nikolaos Scarmeas, Polychronis Economou, Panagiotis Alexopoulos

{"title":"Depressive symptoms in the entire spectrum of cognitive ageing in Greece: evidence from the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD).","authors":"Eleni-Zacharoula Eliza Georgiou, Antonios Politis, Mary H Kosmidis, Mary Yannakoulia, Efthimios Dardiotis, Georgios Hadjigeorgiou, Paraskevi Sakka, Nikolaos Scarmeas, Polychronis Economou, Panagiotis Alexopoulos","doi":"10.1080/13651501.2023.2296889","DOIUrl":"10.1080/13651501.2023.2296889","url":null,"abstract":"Objectives: To study (i) the prevalence of mild and moderate-to-severe depressive symptoms in the entire spectrum of cognitive ageing in Greece and (ii) the relationship between these symptoms and demographic and clinical data.Methods: The study was based on the randomly selected cohort of the Hellenic Longitudinal Investigation of Aging and Diet (HELIAD). Depressive symptoms were assessed with the 15-item version of the Geriatric Depression Scale. Participants also received a comprehensive neuropsychological assessment, while the clinical diagnoses of dementia and mild cognitive impairment were established according to international diagnostic criteria. Statistical analyses relied on comparison tests and a logistic (proportional odds) ordinal regression model.Results: Depressive symptoms were detected in 19.5% of the 1936 study participants, while 11.3% of both people with MCI and dementia had moderate-to-severe depressive symptoms. The regression model revealed that older adults with more severe depressive symptoms were more likely female, cognitively impaired, less educated, were treated with psychotropic medication and lived in Attica versus Thessaly.Conclusions: Since depressive symptoms were detected in almost one in five older adults, healthcare professionals in Greece should safeguard the timely detection and effective treatment of such symptoms and the post-diagnostic care of older adults with depression.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"27-34"},"PeriodicalIF":3.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139032272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0