International Journal of Psychiatry in Clinical Practice最新文献_第2页

Can simple biomarkers of inflammation guide the diagnosis of psychiatric disorders? 简单的炎症生物标志物能否指导精神疾病的诊断？

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-06-01 Epub Date: 2024-10-07 DOI: 10.1080/13651501.2024.2412641

Ozgur Ozkalayci, Nihal Tastekin

{"title":"Can simple biomarkers of inflammation guide the diagnosis of psychiatric disorders?","authors":"Ozgur Ozkalayci, Nihal Tastekin","doi":"10.1080/13651501.2024.2412641","DOIUrl":"10.1080/13651501.2024.2412641","url":null,"abstract":"Objective: In this study, we wanted to investigate the usability of routine blood samples taken at the beginning of hospitalisation in inpatients to predict the presence of psychotic symptoms in patients.Methods: We divided the hospitalised patients into two groups those with and without psychotic symptoms according to their ICD-10 diagnosis codes. Then, we compared the complete blood count, c-reactive protein (CRP), and fasting glucose levels, which can be used as simple markers of inflammation.Results: In this retrospective study, which included 349 patients, we found that blood leukocytes, neutrophils, CRP, and fasting glucose levels were higher in patients with psychotic symptoms than in patients without psychotic symptoms (p = 0.015; p = 0.013; p = 0.002; and p = 0.001, respectively). According to regression analysis, patients with high glucose levels were 4.9 times more likely to have psychotic symptoms than those with low glucose levels. In addition, according to the ROC analysis results; when we used 87 mg/dl as the cut-off value for fasting glucose, it was observed that it predicted psychotic symptoms with approximately 69% sensitivity and 71% specificity.Conclusion: Although our results still have some limitations, they are promising for the future use of simple biomarkers of inflammation for the differential diagnosis of psychiatric disorders.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"107-113"},"PeriodicalIF":2.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between coping strategies and change in symptom severity in contamination-focused OCD patients during the COVID-19: a one-year follow-up. 在 COVID-19 测试中，以污染为重点的强迫症患者的应对策略与症状严重程度变化之间的关系：一年随访。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-06-01 Epub Date: 2024-10-25 DOI: 10.1080/13651501.2024.2420641

Emine Cengiz Cavusoglu, Arda Kazim Demirkan

{"title":"Relationship between coping strategies and change in symptom severity in contamination-focused OCD patients during the COVID-19: a one-year follow-up.","authors":"Emine Cengiz Cavusoglu, Arda Kazim Demirkan","doi":"10.1080/13651501.2024.2420641","DOIUrl":"10.1080/13651501.2024.2420641","url":null,"abstract":"Objective: To examine the relationship between coping strategies and the change in symptom severity in contamination-focused OCD patients during the COVID-19 pandemic over a one-year follow-up.Methods: In March 2020, a one-year follow-up study was initiated with 56 contamination-focused OCD patients in Turkey. Coping strategies were evaluated using the COPE scale. OCD symptom severity was assessed using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) at the beginning and end of the year. The Fear of COVID-19 Scale was administered mid-year.Results: One year post the onset of COVID-19, 68% of patients showed increased OCD symptom severity, while 32% displayed a decrease. Higher scores on the fear of COVID-19 scale and lower acceptance scores from COPE subscales were correlated with increased OCD symptom severity.Conclusions: The COVID-19 pandemic has intensified OCD symptoms in a substantial proportion of patients, particularly those with heightened fears related to the pandemic, and reduced acceptance-based coping strategies. Tailored interventions emphasising adaptive coping mechanisms may benefit OCD patients in managing their symptoms during external stressors like pandemics.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"145-151"},"PeriodicalIF":2.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The complex clinical and cognitive phenotype of adult patients with attention deficit hyperactivity disorder (ADHD) and comorbid hoarding disorder. 注意缺陷多动障碍（ADHD）合并囤积症成年患者复杂的临床和认知表型。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-06-01 Epub Date: 2024-11-15 DOI: 10.1080/13651501.2024.2427615

Giacomo Grassi, Corinna Moradei, Chiara Cecchelli, Michael van Ameringen

{"title":"The complex clinical and cognitive phenotype of adult patients with attention deficit hyperactivity disorder (ADHD) and comorbid hoarding disorder.","authors":"Giacomo Grassi, Corinna Moradei, Chiara Cecchelli, Michael van Ameringen","doi":"10.1080/13651501.2024.2427615","DOIUrl":"10.1080/13651501.2024.2427615","url":null,"abstract":"Objectives: Several studies consistently showed that patients with attention deficit hyperactivity disorder (ADHD) have high rates of hoarding disorder (HD) comorbidity. The aim of the present study was to compare the clinical and cognitive features of adult ADHD patients with and without hoarding comorbidity according to a self-report measure, and a sample of healthy controls.Methods: Fifty-seven consecutive adult outpatients with a primary diagnosis of ADHD with comorbid hoarding disorder (ADHD+HD), 57 matched ADHD patients without hoarding disorder comorbidity (ADHD-HD), and a control group of 47 healthy controls (HCs) were enrolled. All subjects undergone a comprehensive clinical assessment and a neurocognitive assessment focused on attention, memory, and executive functions.Results: The ADHD groups differed on most of the clinical and cognitive measures compared to HCs. ADHD+HD patients showed similar ADHD symptoms but greater subjective impulsivity, mood and anxiety symptoms, and a greater functional impairment compared to ADHD-HD patients as well as greater attentional and executive functioning impairments.Conclusions: ADHD patients with comorbid hoarding disorder present a more complex clinical and neuropsychological phenotype correlated to a greater functional impairment compared to ADHD patients without this comorbidity. These results further highlight the relevance of assessing and treating hoarding behaviours in adults with ADHD.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"167-176"},"PeriodicalIF":2.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring real-world prescribing patterns for maintenance treatment in bipolar disorders: a focus on antidepressants and benzodiazepines. 探索现实世界中双相情感障碍维持治疗的处方模式：关注抗抑郁药和苯二氮卓类药物。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-06-01 Epub Date: 2024-09-04 DOI: 10.1080/13651501.2024.2398796

Sanja Andric Petrovic, Dusan Jankovic, Nina Kaurin, Vanja Mandic Maravic, Danilo Pesic, Ivan Ristic, Nadja P Maric

{"title":"Exploring real-world prescribing patterns for maintenance treatment in bipolar disorders: a focus on antidepressants and benzodiazepines.","authors":"Sanja Andric Petrovic, Dusan Jankovic, Nina Kaurin, Vanja Mandic Maravic, Danilo Pesic, Ivan Ristic, Nadja P Maric","doi":"10.1080/13651501.2024.2398796","DOIUrl":"10.1080/13651501.2024.2398796","url":null,"abstract":"Objective: Bipolar disorders (BD) are characterized by highly recurrent nature, necessitating adequate maintenance treatment for long-term disorder control. This study aimed to investigate real-world prescribing patterns among outpatients with BD, focusing on the utilisation of antidepressants (AD) and benzodiazepines (BDZ).Methods: We analysed prescription patterns of the five main groups of psychotropic medications (antipsychotics, mood stabilizers, AD, BDZ, and anticholinergic medications) and their relationships with basic socio-demographic and clinical data in a sample of 107 clinically stable BD outpatients (75.7% female, age 44.8 ± 11.7).Results: Maintenance therapy predominantly involved polypharmacy (92.5%), with mood stabilizers (87.9%) and antipsychotics (80.4%, predominantly second-generation) being the most commonly prescribed. Our findings highlight a high percentage of patients prescribed AD (50.5%) and BDZ (54.2%). BDZ patients, compared to the non-BDZ group in maintenance treatment, were significantly older with longer psychiatric history and a decreased likelihood of comorbid personality disorder diagnoses.Conclusions: This study offers insights into prescribing practices within a university psychiatric clinic in the Western Balkans. The prevalent use of polypharmacy in real-world clinical settings, along with high percentage of patients prescribed AD and BDZ, suggests a gap between guideline recommendations and clinical practice, indicating a lack of consensus or standardized approaches in clinical practice.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"94-101"},"PeriodicalIF":2.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurobiological and psychological factors to depression. 抑郁症的神经生物学和心理学因素。

IF 2.9 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-06-01 Epub Date: 2024-08-05 DOI: 10.1080/13651501.2024.2382091

Malini Turner

引用次数: 0

Prevalence of suicide attempt, suicide ideation and self-harm at diagnosis in adolescents with eating disorders 患有饮食失调症的青少年在确诊时自杀未遂、自杀意念和自残行为的发生率

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-09 DOI: 10.1080/13651501.2024.2337796

Sinem Akgül, Melis Pehlivantürk Kızılkan, Ayşegül Yıldırım, Orhan Derman

引用次数: 0

Effects of seasonality in emergency admissions for mental disorders: two years of clinical experience 精神障碍急诊入院的季节性影响：两年的临床经验

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-08 DOI: 10.1080/13651501.2024.2331481

Thomas Fraccalini, Valerio Ricci, Beatrice Tarozzo, Luciano Cardinale, Giuseppe Primerano, Meraji Kowsaralsadat, Giacomo Piccininni, Adriana Boccuzzi, Giuseppe Maina, Giovanni Volpicelli

引用次数: 0

Suicide ideation and male-female differences in major depressive disorder 自杀意念与重度抑郁障碍的男女差异

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-08 DOI: 10.1080/13651501.2024.2335950

Paolo Olgiati, Basilio Pecorino, Alessandro Serretti

引用次数: 0

Editorial: Embracing continuity and diversity in psychiatric practice 社论：拥抱精神科实践的连续性和多样性

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-04-03 DOI: 10.1080/13651501.2024.2336822

Pia Baldinger-Melich

引用次数: 0

The relevance of anti-N-methyl-d-aspartate receptor encephalitis for psychiatrists 抗 N-甲基-d-天冬氨酸受体脑炎对精神科医生的意义

IF 3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2024-03-04 DOI: 10.1080/13651501.2024.2323926

Denis Pavăl, Nicoleta Gherghel-Pavăl, Octavia Oana Căpățînă, Adina Stan, Ioana Valentina Micluția

引用次数: 0