Clara Lombardo, Maria Catena Silvestri, Fiammetta Iannuzzo, Fabrizio Turiaco, Giovanni Genovese, Maria Rosaria Anna Muscatello, Antonio Bruno, Carmela Mento, Gianluca Pandolfo
{"title":"Exploring the role of subthreshold autistic traits on body image uneasiness: a study among Italian female with eating disorders.","authors":"Clara Lombardo, Maria Catena Silvestri, Fiammetta Iannuzzo, Fabrizio Turiaco, Giovanni Genovese, Maria Rosaria Anna Muscatello, Antonio Bruno, Carmela Mento, Gianluca Pandolfo","doi":"10.1080/13651501.2025.2517843","DOIUrl":"10.1080/13651501.2025.2517843","url":null,"abstract":"<p><strong>Objective: </strong>The present study evaluate the presence of subthreshold autistic traits, assess the level of body image dissatisfaction, and explore their potential association in female patients with eating disorders.</p><p><strong>Method: </strong>The study used the Adult Autism Subthreshold Spectrum - AdAS and the Body Uneasiness Test - BUT to identify autistic traits that predict body image distress, applying linear and stepwise regression.</p><p><strong>Results: </strong>The sample consisted of 49 female patients with eating disorders with a mean duration of illness of 4 years. Regression analysis indicated that BUT 'Weight Phobia' factor was positively associated with AdAS 'Non-Verbal communication' and 'Inflexibility and adherence to routine' domains, BUT 'Body Image Concerns' factor was associated with AdAS 'Non-Verbal communication' and 'Inflexibility and adherence to routine' domains. BUT 'Compulsive Self-Monitoring' factor was associated with AdAS 'Inflexibility and adherence to routine' domain and, finally BUT 'Depersonalization' factor was positively associated with AdAS 'Hyper- and hypo reactivity to sensory input'. The average AdAS score is 73.8 (± SD 22.8).</p><p><strong>Conclusions: </strong>The study highlights that subthreshold autistic traits may play a role in altering body image in patients with eating disorders, possibly due to altered sensory perception. Further research is needed to explore causes and therapies.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"130-135"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriele Di Salvo, Lorenzo Filippo, Camilla Perotti, Luca Pellegrini, Gianluca Rosso, Giuseppe Maina
{"title":"Adult ADHD: associated medical conditions and related factors.","authors":"Gabriele Di Salvo, Lorenzo Filippo, Camilla Perotti, Luca Pellegrini, Gianluca Rosso, Giuseppe Maina","doi":"10.1080/13651501.2025.2517050","DOIUrl":"10.1080/13651501.2025.2517050","url":null,"abstract":"<p><strong>Objective: </strong>The study aims to investigate the prevalence of general medical conditions (GMCs) within a sample of adult with Attention Deficit Hyperactivity Disorder (ADHD) and to ascertain whether such comorbidities may correlate with specific socio-demographic or clinical parameters.</p><p><strong>Methods: </strong>The sample included 196 outpatients with adult ADHD. Binary logistic regression (LogReg) was used to identify explanatory variables associated with GMC.</p><p><strong>Results: </strong>Ninety-four subjects (48%) had at least one GMC. ADHD patients with GMCs showed more psychiatric family history (56.7% vs 30.9%), more comorbidities with bipolar spectrum disorders (17% vs 5.9%), and greater impairment in social functioning (67% vs 52.9%). At the LogReg analysis, only the association with psychiatric family history and comorbidity with bipolar disorder remained significant.</p><p><strong>Conclusions: </strong>We observed a high prevalence of GMC among adult ADHD outpatients. The association found between GMC and a family history of psychiatric disorders allows to hypothesise that there may be a genetic predisposition substrate to both GMC and psychiatric disorders, while the association between GMC and comorbidity with bipolar spectrum disorders can be explained by the tendency of bipolar disorder itself to be associated with GMC. It appears crucial in these patients to perform routine medical examinations and to implement a healthy lifestyle.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"125-129"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nagihan Cevher Binici, Ayşe Kutlu, Çisel Yazan Songür, Hande Emine Sabah Barış
{"title":"Comparative analysis of regressive and non-regressive autism: a study of clinical patterns and environmental risk factors in Turkey.","authors":"Nagihan Cevher Binici, Ayşe Kutlu, Çisel Yazan Songür, Hande Emine Sabah Barış","doi":"10.1080/13651501.2025.2519522","DOIUrl":"10.1080/13651501.2025.2519522","url":null,"abstract":"<p><strong>Objective: </strong>This study compared clinical features, symptom severity, and prenatal/perinatal risk factors in children with regressive (ASD-R) and non-regressive autism spectrum disorder (ASD-NR) in a Turkish paediatric sample.</p><p><strong>Method: </strong>A retrospective cross-sectional study was conducted with 143 children aged 2-6 years diagnosed with ASD, grouped as ASD-R (n = 29) or ASD-NR (n = 114). Symptom severity was assessed using the CARS, AuBC, and ABC. Data on prenatal and perinatal factors, epilepsy, and parental age were collected.</p><p><strong>Results: </strong>No significant differences were found in CARS, AuBC, or total ABC scores, except for higher lethargy/social withdrawal scores in the ASD-NR group. Prenatal and perinatal risk factors and epilepsy prevalence were similar. However, parental ages at birth were significantly higher in the ASD-R group. Logistic regression did not yield significant predictors of regression.</p><p><strong>Conclusion: </strong>The findings suggest that prenatal and perinatal factors may influence developmental regression in ASD when interacting with genetic vulnerability. Longitudinal studies are needed to clarify the role of early environmental exposures and epigenetic mechanisms in regression patterns.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"136-143"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction.","authors":"","doi":"10.1080/13651501.2025.2527430","DOIUrl":"10.1080/13651501.2025.2527430","url":null,"abstract":"","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"177"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandra Caqueo-Urízar, Felipe Ponce-Correa, J Francisco Santibáñez-Palma, Alfonso Urzúa, Laurent Boyer
{"title":"Quality of life in Patients with Schizophrenia-spectrum Disorder: A longitudinal study with 10 years of follow-up.","authors":"Alejandra Caqueo-Urízar, Felipe Ponce-Correa, J Francisco Santibáñez-Palma, Alfonso Urzúa, Laurent Boyer","doi":"10.1080/13651501.2025.2517049","DOIUrl":"10.1080/13651501.2025.2517049","url":null,"abstract":"<p><strong>Background: </strong>Quality of life (QoL) in patients with Schizophrenia has become one of the most important outcome measures in long-term treatment; however, in the Latin American context, longitudinal research that analyzes its trajectories over time and its relationship with clinical and sociodemographic aspects is still scarce. The aim of this study was to longitudinally evaluate QoL in conjunction with psychotic symptomatology, internalised stigma, social cognition, premorbid adjustment, and years of untreated psychosis in a sample of patients with a diagnosis of Schizophrenia in Northern Chile.</p><p><strong>Method: </strong>A total of 26 patients were able to complete the 10-year follow-up of measures and predictors of stigma, which were evaluated in Public Outpatient Mental Health Centres in the city of Arica between March-July 2012 and March-July 2022. The results show that QoL trajectories improve over time, especially in aspects such as family relationships, autonomy and resilience. On the other hand, depressive symptoms, self-stigma and premorbid adjustment were significant predictors of follow-up measures of QoL.</p><p><strong>Discussion: </strong>These results underscore the importance of overcoming stigma and depressive symptomatology to improve the QoL of patients with Schizophrenia. Also, the results yielded that premorbid successful psychosocial functioning and experiences are a significant predictor of QoL.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"117-124"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Loneliness and suicidal behaviour in military veterans.","authors":"Leo Sher","doi":"10.1080/13651501.2025.2523291","DOIUrl":"10.1080/13651501.2025.2523291","url":null,"abstract":"<p><strong>Objective: </strong>Loneliness can be defined as a subjective distressing experience that results from perceived isolation or the difference between an individual's preferred and actual social experience. Loneliness is associated with an increase in the incidence of psychiatric and medical disorders and suicidal behaviour. The goal of this article is to attract attention to underappreciated issues of loneliness in veterans and suicidality in lonely veterans.</p><p><p><b>Methods:</b> A review of the relevant literature.</p><p><strong>Results: </strong>Military veterans have unique experiences of loneliness, especially older veterans. Suicide in veterans is a major social issue. Studies suggest that loneliness may contribute to suicidality among veterans. Loneliness is a transdiagnostic suicide prevention and intervention target in the veteran population.</p><p><strong>Conclusions: </strong>Prevention of suicide in lonely veterans should include six components: (1) Recognition of loneliness; (2) Reduction of loneliness; (3) Management of psychiatric and medical disorders; (4) Assessment of suicide risk; (5) Restricting access to the means for suicide; and (6) Specific interventions to reduce suicidality.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"170-176"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelica De Sandi, Giordano D'Urso, Edoardo Nicolò Aiello, Natale Vincenzo Maiorana, Mariachiara Calloni, Denise Mellace, Angelica Marfoli, Gaia Del Prete-Ferrucci, Barbara Poletti, Sergio Barbieri, Alberto Priori, Roberta Ferrucci
{"title":"Relationship between creativity and schizophrenia: a study of patients with psychiatric disorders.","authors":"Angelica De Sandi, Giordano D'Urso, Edoardo Nicolò Aiello, Natale Vincenzo Maiorana, Mariachiara Calloni, Denise Mellace, Angelica Marfoli, Gaia Del Prete-Ferrucci, Barbara Poletti, Sergio Barbieri, Alberto Priori, Roberta Ferrucci","doi":"10.1080/13651501.2025.2528695","DOIUrl":"10.1080/13651501.2025.2528695","url":null,"abstract":"<p><strong>Objective: </strong>Creativity is the ability to generate original ideas, solutions and new concepts. This includes divergent thinking, defined as the ability to think outside of established patterns. Research has focused on the link between creativity and schizophrenia, but results are heterogeneous and contradictory. This study examined divergent thinking using the Divergent Thinking Test (DTT), which compared healthy subjects and subjects with a psychiatric disorder, including schizophrenia.</p><p><strong>Methods: </strong>48 Patients (schizophrenia, <i>n</i> = 20, psychiatric disorder other than schizophrenia, <i>n</i> = 28) and 38 healthy subjects performed the DTT, which includes five factor scores: fluidity (FL), flexibility (FS), originality (O), elaboration (E), title (T). Linear models were employed for between-group comparisons.</p><p><strong>Results: </strong>The results indicated that psychiatric patients show a lower performance on the DTT than healthy subjects. Within the patient group, subjects with schizophrenia show greater difficulties than subjects with other psychiatric disorders.</p><p><strong>Conclusions: </strong>The DTT scores of the control group are higher than those of the psychiatric group. Regarding to the type of diagnosis, performance on the DTT task is lower in schizophrenic patients than in patients with another psychiatric disorder, suggesting the existence of a negative association between creativity and schizophrenia.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"160-166"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefan Jerotic, Milica Nestorovic, Janko Nesic, Anastazja Szuła, Marcin Moskalewicz
{"title":"When mood and time align: nasal esketamine reduces lived time disturbances in treatment-resistant depression.","authors":"Stefan Jerotic, Milica Nestorovic, Janko Nesic, Anastazja Szuła, Marcin Moskalewicz","doi":"10.1080/13651501.2025.2528692","DOIUrl":"10.1080/13651501.2025.2528692","url":null,"abstract":"<p><p>These two cases highlight the utility of a focused, structured clinical phenomenological interview in measuring treatment effectiveness in subjective experience. Two male patients, aged 35 and 27, of Serbian ethnicity with treatment-resistant depression were treated with nasal esketamine, with clinical progress monitored using both the Montgomery-Åsberg Depression Rating Scale (MADRS) and the Transdiagnostic Assessment of Temporal Experience (TATE), a structured instrument assessing the patient's felt sense of time. Notably, TATE scores in the first case reached general population levels at week 4, one week prior to the treatment response, as indicated by MADRS. These findings underscore the value of phenomenological assessments in complementing traditional depression scales to capture nuanced improvements during treatment.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"167-169"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of legislative amendment on the use of seclusion and restraint in psychiatry: a French mirror-image study.","authors":"Dolly Dronnier, Assia Mazari, Eirini Rari, Catherine Martelli, Amine Benyamina, Bruno Roméo","doi":"10.1080/13651501.2025.2537661","DOIUrl":"10.1080/13651501.2025.2537661","url":null,"abstract":"<p><strong>Introduction: </strong>A legislative amendment regarding seclusion and restraint in psychiatry was enacted in France in 2020, aligning with global efforts to reduce coercive measures in mental health care. This study aimed to evaluate whether the amendment was associated with a change in these clinical practices.</p><p><strong>Methods: </strong>A single-centre, mirror-image observational study was conducted, analysing data from hospitalised patients subjected to seclusion and/or restraint between May 2018 and September 2023. Sociodemographic and clinical data were compared for patients before and after the legislative change.</p><p><strong>Results: </strong>The study included 126 patients, with 77 requiring both seclusion and restraint. Results indicated no significant effect of the amendment on the frequency of seclusion (<i>p</i> = .7) or restraint (<i>p</i> = .7). Similarly, no differences were observed in the duration of seclusion (<i>p</i> = .4) or restraint (<i>p</i> = .6). Sociodemographic and clinical characteristics remained consistent between the two periods.</p><p><strong>Conclusion: </strong>The findings suggest that the legislative amendment was not associated with a change in practices. This highlights the need for complementary strategies such as staff training, institutional initiatives, and resource allocation to effectively reduce coercive measures. Further multicentric and longitudinal studies are recommended to assess the broader and long-term impacts of the law.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"152-159"},"PeriodicalIF":2.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between heart rate variability and emotion dysregulation in adolescents with non-suicidal self-injury.","authors":"Maya Aulya Saputri, Andrian Fajar Kusumadewi, Kamilaturrizqi Sakinah","doi":"10.1080/13651501.2025.2551772","DOIUrl":"https://doi.org/10.1080/13651501.2025.2551772","url":null,"abstract":"<p><strong>Introduction: </strong>Non-suicidal self-injury (NSSI) is a strong predictor of increased future suicidal ideation and risk. The highest prevalence of NSSI is in adolescents. NSSI is performed as a maladaptive response to emotion regulation distress when facing an intense negative emotional load. One of the physiological markers of Emotion Dysregulation (ED) can be measured quantitatively through changes in Heart Rate Variability (HRV).</p><p><strong>Objective: </strong>The purpose of this review is to provide an overview about studies on HRV and ED in adolescents with NSSI to shed light on potential associations and to identify prospective approaches for future studies.</p><p><strong>Method: </strong>Literature was searched through Pubmed using Heart Rate Variability (HRV), Emotion Dysregulation (ED), and Non Suicidal Self-Injury (NSSI) as the keywords. Inclusion criteria were full-text journal articles in English or Indonesian within the last 10 years.</p><p><strong>Results: </strong>Studies show that ED in certain mental disorders has been associated with HRV changes through the autonomic nervous system imbalance pathway. For individuals with ED, NSSI may serve certain perceived benefits, reinforcing its repetition whenever adverse events are encountered.</p><p><strong>Conclusions: </strong>ED in adolescents with NSSI can be observed through HRV reduction. This approach may help improve adolescent mental health by reducing NSSI and preventing suicidal tendencies.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-6"},"PeriodicalIF":2.7,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}