Adult ADHD: associated medical conditions and related factors.

IF 2.9 4区医学 Q2 PSYCHIATRY

International Journal of Psychiatry in Clinical Practice Pub Date : 2025-06-17 DOI:10.1080/13651501.2025.2517050

Gabriele Di Salvo, Lorenzo Filippo, Camilla Perotti, Luca Pellegrini, Gianluca Rosso, Giuseppe Maina

{"title":"Adult ADHD: associated medical conditions and related factors.","authors":"Gabriele Di Salvo, Lorenzo Filippo, Camilla Perotti, Luca Pellegrini, Gianluca Rosso, Giuseppe Maina","doi":"10.1080/13651501.2025.2517050","DOIUrl":null,"url":null,"abstract":"Objective: The study aims to investigate the prevalence of general medical conditions (GMCs) within a sample of adult with Attention Deficit Hyperactivity Disorder (ADHD) and to ascertain whether such comorbidities may correlate with specific socio-demographic or clinical parameters.Methods: The sample included 196 outpatients with adult ADHD. Binary logistic regression (LogReg) was used to identify explanatory variables associated with GMC.Results: Ninety-four subjects (48%) had at least one GMC. ADHD patients with GMCs showed more psychiatric family history (56.7% vs 30.9%), more comorbidities with bipolar spectrum disorders (17% vs 5.9%), and greater impairment in social functioning (67% vs 52.9%). At the LogReg analysis, only the association with psychiatric family history and comorbidity with bipolar disorder remained significant.Conclusions: We observed a high prevalence of GMC among adult ADHD outpatients. The association found between GMC and a family history of psychiatric disorders allows to hypothesise that there may be a genetic predisposition substrate to both GMC and psychiatric disorders, while the association between GMC and comorbidity with bipolar spectrum disorders can be explained by the tendency of bipolar disorder itself to be associated with GMC. It appears crucial in these patients to perform routine medical examinations and to implement a healthy lifestyle.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-5"},"PeriodicalIF":2.9000,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Psychiatry in Clinical Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/13651501.2025.2517050","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: The study aims to investigate the prevalence of general medical conditions (GMCs) within a sample of adult with Attention Deficit Hyperactivity Disorder (ADHD) and to ascertain whether such comorbidities may correlate with specific socio-demographic or clinical parameters.

Methods: The sample included 196 outpatients with adult ADHD. Binary logistic regression (LogReg) was used to identify explanatory variables associated with GMC.

Results: Ninety-four subjects (48%) had at least one GMC. ADHD patients with GMCs showed more psychiatric family history (56.7% vs 30.9%), more comorbidities with bipolar spectrum disorders (17% vs 5.9%), and greater impairment in social functioning (67% vs 52.9%). At the LogReg analysis, only the association with psychiatric family history and comorbidity with bipolar disorder remained significant.

Conclusions: We observed a high prevalence of GMC among adult ADHD outpatients. The association found between GMC and a family history of psychiatric disorders allows to hypothesise that there may be a genetic predisposition substrate to both GMC and psychiatric disorders, while the association between GMC and comorbidity with bipolar spectrum disorders can be explained by the tendency of bipolar disorder itself to be associated with GMC. It appears crucial in these patients to perform routine medical examinations and to implement a healthy lifestyle.

查看原文本刊更多论文

成人多动症：相关医疗条件和相关因素。

目的：本研究旨在调查患有注意缺陷多动障碍（ADHD）的成人样本中一般医疗状况（GMCs）的患病率，并确定这些合并症是否与特定的社会人口统计学或临床参数相关。方法：收集成人ADHD门诊患者196例。采用二元逻辑回归（loggreg）识别与GMC相关的解释变量。结果：94名受试者（48%）至少有一次GMC。伴有gmc的ADHD患者表现出更多的精神家族史（56.7%对30.9%），更多的双相情感障碍合并症（17%对5.9%），以及更大的社会功能障碍（67%对52.9%）。在LogReg的分析中，只有与精神家族史和双相情感障碍共病的关联仍然显著。结论：我们观察到成人ADHD门诊患者中GMC的患病率很高。GMC与精神疾病家族史之间的关联允许假设GMC和精神疾病可能存在遗传易感性底物，而GMC与双相情感障碍共病之间的关联可以通过双相情感障碍本身与GMC相关的倾向来解释。对这些病人来说，进行常规医学检查和实行健康的生活方式似乎至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Psychiatry in Clinical Practice 医学-精神病学

CiteScore

6.00

自引率

3.30%

发文量

审稿时长

>12 weeks

期刊介绍： International Journal of Psychiatry in Clinical Practice provides an international forum for communication among health professionals with clinical, academic and research interests in psychiatry. The journal gives particular emphasis to papers that integrate the findings of academic research into realities of clinical practice. Focus on the practical aspects of managing and treating patients. Essential reading for the busy psychiatrist, trainee and interested physician. Includes original research papers, comprehensive review articles and short communications. Key words: Psychiatry, Neuropsychopharmacology, Mental health, Neuropsychiatry, Clinical Neurophysiology, Psychophysiology, Psychotherapy, Addiction, Schizophrenia, Depression, Bipolar Disorders and Anxiety.