International Journal of Psychiatry in Clinical Practice最新文献

Presenting a new scoring system based on clinical and inflammatory factors to classify the severity of bipolar disorder. 提出了一种新的基于临床和炎症因素的双相情感障碍严重程度评分系统。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-10-06 DOI: 10.1080/13651501.2026.2739885

Maryam Mousavibazaz, Niloufar Mahdavi Hezaveh, Yousef Semnani, Soheila Kianpour Rad

{"title":"Presenting a new scoring system based on clinical and inflammatory factors to classify the severity of bipolar disorder.","authors":"Maryam Mousavibazaz, Niloufar Mahdavi Hezaveh, Yousef Semnani, Soheila Kianpour Rad","doi":"10.1080/13651501.2026.2739885","DOIUrl":"https://doi.org/10.1080/13651501.2026.2739885","url":null,"abstract":"Background: Various clinical and laboratory factors are related to the severity of bipolar disorder, but there is no global agreement for the role of these factors.Methods: Forty patients with the definitive diagnosis of bipolar disorder were included in this prospective study. The severity of the disease was measured by the Young Mania Rating Scale (YMRS). using the SPSS software.Results: Using multivariable logistic regression modelling, the main correlates for moderate to severe bipolar disease included baseline interleukin-6 level > 5.5 pg/ml (OR = 2.820, p = 0.001), disease duration >7.5 years (OR = 2.155, p = 0.003), and positive family history of bipolar disease (OR = 1.300, p = 0.036). Based on the weight of these three factors, a scoring system was designed for the severity of the disorder, which ranged from 3 to 9. A total risk score of less than 5, between 5 and 7, or higher than 7 was considered low or moderate and high.Conclusion: The use of the presented new scoring system provides the possibility of classifying the severity of the disorder and, therefore, the possibility of better treatment and management of the illness.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-5"},"PeriodicalIF":2.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Everything you always wanted to know about sleep, but you were afraid to ask: expert concise guide and recommendations on assessing sleep-wake disturbances within a psychiatric context in contemporary times. 你一直想知道的关于睡眠的一切，但你不敢问：在当代精神病学背景下评估睡眠-觉醒障碍的专家简明指南和建议。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-10-06 DOI: 10.1080/13651501.2026.2743008

Laura Palagini, Anna Castelnovo, Armando D'Agostino, Matteo Balestrieri, Bearnardo M Dell'Osso, Andrea Fagiolini, Luigi Ferini Strambi, Pierre A Geoffroy, Claudio Liguori, Giovanni Martinotti, Claudio Mencacci, Lino Nobili, Dieter Riemann, Gabriele Sani, Gianluca Serafini, Antonio Vita, Andrea Fiorillo

{"title":"Everything you always wanted to know about sleep, but you were afraid to ask: expert concise guide and recommendations on assessing sleep-wake disturbances within a psychiatric context in contemporary times.","authors":"Laura Palagini, Anna Castelnovo, Armando D'Agostino, Matteo Balestrieri, Bearnardo M Dell'Osso, Andrea Fagiolini, Luigi Ferini Strambi, Pierre A Geoffroy, Claudio Liguori, Giovanni Martinotti, Claudio Mencacci, Lino Nobili, Dieter Riemann, Gabriele Sani, Gianluca Serafini, Antonio Vita, Andrea Fiorillo","doi":"10.1080/13651501.2026.2743008","DOIUrl":"https://doi.org/10.1080/13651501.2026.2743008","url":null,"abstract":"Objective: While disrupted sleep has long been linked to mental disorders there has been a notable decrease in interest and sleep-wake disorders have received low priority in psychiatric care. The aim of the paper was to present a concise guide for evaluating common sleep-wake disturbances within a psychiatric framework to revitalise the importance of sleep in psychiatry.Methods: A systematic search strategy was conducted on the importance of sleep-wake assessment in psychiatry (search #1), the typology of sleep-wake disturbances in psychiatric practice (search #2), the guidelines on assessment of sleep-wake disturbances (search#3). Results were summarised and discussed in a narrative way.Results: Evidence suggests that assessing sleep-wake disturbances improves prevention and treatment outcomes in psychiatric patients. Insomnia remains the most common disorder, though other sleep disturbances are highly prevalent. A structured two-step evaluation-combining initial patient clinical interviews with standardised self-report questionnaires-may assist in diagnosis and monitor outcomes.Conclusion: A concise guide on how to assess sleep-wake disturbances in psychiatry was summarised for psychiatric clinical practice.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-11"},"PeriodicalIF":2.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse childhood experiences and autism spectrum disorder: a retrospective cohort study among late adolescents. 不良童年经历与自闭症谱系障碍：一项晚期青少年的回顾性队列研究。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-10-05 DOI: 10.1080/13651501.2026.2743009

Shlomi Abuhasira, Leah Shelef, Liya Kerem, Jacob Rotschield, Shir Lerner, Ariel Tenenbaum

{"title":"Adverse childhood experiences and autism spectrum disorder: a retrospective cohort study among late adolescents.","authors":"Shlomi Abuhasira, Leah Shelef, Liya Kerem, Jacob Rotschield, Shir Lerner, Ariel Tenenbaum","doi":"10.1080/13651501.2026.2743009","DOIUrl":"https://doi.org/10.1080/13651501.2026.2743009","url":null,"abstract":"Objective: To examine the association between Adverse Childhood Experiences (ACEs) and Autism Spectrum Disorder (ASD) identification among Israel Defense Forces (IDF) personnel, focusing on predictors of ASD identification during military service.Methods: A retrospective cohort study was conducted on 288,633 IDF conscripts evaluated between 2009 and 2021. ASD diagnoses at enlistment and during service were analysed in relation to demographic factors, cognitive scores, and self-reported ACEs. Logistic regression was used to assess predictors of in-service ASD diagnosis.Results: At enlistment, 935 individuals (0.33%) had an ASD diagnosis, and 635 were identified during service. Those with ASD were more likely to be male (90.1%), Jewish (97.9%), Israeli-born (91.4%), from higher socioeconomic backgrounds, and to have ≥12 years of education and high IQ scores (31.8% vs. 19.7%, p < .001). Several ACEs, including emotional/verbal abuse, physical abuse, neglect, parental substance use, and incarceration, were significantly associated with ASD identification during service. A cumulative ACE score of ≥2 predicted ASD diagnosis with an odds ratio of 2.27.Conclusions: Early-life adversity is associated with increased risk of ASD identification during military service. Integrating ACE screening into enlistment procedures may help identify recruits at risk for later ASD identification and facilitate timely clinical interventions.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-8"},"PeriodicalIF":2.3,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility, tolerability, and preliminary effectiveness of an accelerated bilateral intermittent theta-burst stimulation protocol in adults with posttraumatic stress disorder and comorbid depressive disorder following mild traumatic brain injury. 加速双侧间歇性脑波爆发刺激方案在轻度颅脑损伤后创伤后应激障碍和共病抑郁症患者中的可行性、耐受性和初步有效性

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-19 DOI: 10.1080/13651501.2026.2733584

Safa Rubaye, Aditya Shah, Waleed Aldulaimy, Ashley Hernandez, Hannah Park, Verena Sorial, Pooja Prasad, Seema Iyengar

{"title":"Feasibility, tolerability, and preliminary effectiveness of an accelerated bilateral intermittent theta-burst stimulation protocol in adults with posttraumatic stress disorder and comorbid depressive disorder following mild traumatic brain injury.","authors":"Safa Rubaye, Aditya Shah, Waleed Aldulaimy, Ashley Hernandez, Hannah Park, Verena Sorial, Pooja Prasad, Seema Iyengar","doi":"10.1080/13651501.2026.2733584","DOIUrl":"https://doi.org/10.1080/13651501.2026.2733584","url":null,"abstract":"Posttraumatic stress disorder (PTSD), depressive disorder, and persistent post-concussive symptoms commonly co-occur after mild traumatic brain injury (TBI). Evidence is limited for accelerated bilateral intermittent theta-burst stimulation (AB-iTBS) in outpatient care for this triad. Single-site retrospective cohort of 64 AB-iTBS courses in 55 adults (aged 18-69; 52.7% female) with PTSD, depressive disorder, and predominantly mild TBI (2023-2026). The protocol delivered 20 sessions/day for 4 days (80/course), alternating left and right dorsolateral prefrontal cortex at 120% resting motor threshold (600-pulse theta-burst). Outcomes were feasibility, tolerability, and within-patient change in PHQ-9, PCL-5, GAD-7, and PSS at Post-treatment and Follow-up. 55/64 courses (85.9%; 95% CI, 75.0-93.4) completed; no treatment-emergent adverse events (0/64; 95% CI, 0.0-5.6). Baseline-to-Follow-up reductions were significant for PHQ-9 (dz = -0.60; p = .004), PCL-5 (dz = -0.54; p = .008), GAD-7 (dz = -0.77; p < .001), and PSS (dz = -0.67; p = .002). At Follow-up, response was 35.7% (PHQ-9), 50.0% (PCL-5), and 44.4% (GAD-7); remission was 35.0%, 33.3%, and 44.4%. Overall improvement increased from Post-treatment to Follow-up; 20.0%-28.6% first met criterion at Follow-up. AB-iTBS protocol was feasible, tolerated without documented adverse events, and associated with short-term improvement across depressive, posttraumatic, anxiety, and perceived-stress domains.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-12"},"PeriodicalIF":2.3,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and associated factors of cognitive impairment in patients with major depressive disorder: a cross-sectional study in Vietnam. 越南重度抑郁症患者认知障碍的患病率及相关因素：一项横断面研究

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-18 DOI: 10.1080/13651501.2026.2730216

Hung The Nguyen, Nhung Thi Hong Nguyen, Phuc Truong Vinh Le, Linh Tich Ngo, Nghia Trung Tran, Chau Thi Minh Pham, Phu Thi Nguyen, Tho Quoc Truong, Manh Xuan Bui

{"title":"Prevalence and associated factors of cognitive impairment in patients with major depressive disorder: a cross-sectional study in Vietnam.","authors":"Hung The Nguyen, Nhung Thi Hong Nguyen, Phuc Truong Vinh Le, Linh Tich Ngo, Nghia Trung Tran, Chau Thi Minh Pham, Phu Thi Nguyen, Tho Quoc Truong, Manh Xuan Bui","doi":"10.1080/13651501.2026.2730216","DOIUrl":"https://doi.org/10.1080/13651501.2026.2730216","url":null,"abstract":"Objective: Cognitive impairment is increasingly recognised as a core feature of major depressive disorder (MDD), but data from low- and middle-income countries, including Vietnam, remain scarce. This study examined the prevalence of cognitive impairment among patients with MDD and identified associated factors.Method: A cross-sectional study was conducted among 88 outpatients with MDD at the Mental Health Hospital of Ho Chi Minh City (December 2024-July 2025). Sociodemographic and clinical data were collected, cognitive function assessed with the Montreal Cognitive Assessment (MoCA), and logistic regression applied to examine associated factors.Results: The mean MoCA score was 22.6 ± 4.2; 72.7% of participants had cognitive impairment. Verbal fluency, abstraction, and delayed recall were most affected, while orientation and attention were relatively preserved. Older age (OR = 1.1, 95% CI: 1.05-1.3, p = 0.003) and male sex (OR = 0.1, 95% CI: 0.03-0.8, p = 0.021) were significantly associated, while economic dependence showed a weak link (OR = 5.0, 95% CI: 1.01-24.7, p = 0.048).Conclusion: Cognitive impairment is highly prevalent in MDD, especially in executive and memory domains. Older age and male sex were significant predictors, highlighting the need for routine cognitive screening in depression care.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-7"},"PeriodicalIF":2.3,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The distinct roles of assessment method and theoretical framework in predicting functional impairment and alcohol use. 评估方法和理论框架在预测功能障碍和酒精使用中的独特作用。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-04 DOI: 10.1080/13651501.2026.2726385

Tibor Cece Kiss, György Zsolt Rubovszky, Zsolt Demetrovics, Rózsa Vivien Szabó, András Láng

{"title":"The distinct roles of assessment method and theoretical framework in predicting functional impairment and alcohol use.","authors":"Tibor Cece Kiss, György Zsolt Rubovszky, Zsolt Demetrovics, Rózsa Vivien Szabó, András Láng","doi":"10.1080/13651501.2026.2726385","DOIUrl":"10.1080/13651501.2026.2726385","url":null,"abstract":"Objective: The DSM-5 Alternative Model for Personality Disorders (AMPD) and Kernberg's object relations theory are prominent frameworks for assessing personality dysfunction. This study investigates their structural overlap and evaluates their specific capacity to predict clinical outcomes using a multi-method approach.Methods: A sample of 189 Hungarian psychotherapy inpatients (127 females, 55 males, 7 undisclosed; mean age = 34.0 years) were assessed using four personality dysfunction measures (SCID-5-AMPD, STIPO-R, LPFS-BF, IPO) alongside measures of functional impairment (WSAS) and alcohol use risk (AUDIT). Confirmatory Factor Analysis (CFA) and Structural Equation Modelling (SEM) evaluated latent structures and predictive validity.Results: CFA supported a model with three distinct latent constructs: levels of self-functioning, interpersonal functioning, and personality organisation, alongside specific method factors. SEM revealed distinct predictive patterns: general functional impairment was uniquely predicted by descriptive self-functioning, while alcohol use risk was associated with the level of personality organisation. However, these findings are limited to a low-risk inpatient psychotherapy sample and should not be generalised to broader substance-dependent populations.Conclusions: The AMPD and Kernberg models are complementary rather than redundant. Assessing both descriptive functioning and dynamic organisation via a multi-method approach provides a more comprehensive, clinically actionable understanding of personality pathology and specific behavioural risks.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-11"},"PeriodicalIF":2.3,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuropsychiatric characteristics of capgras syndrome in Alzheimer's disease in the CATIE-AD. CATIE-AD中阿尔茨海默病capgras综合征的神经精神特征

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-02 DOI: 10.1080/13651501.2026.2724972

Antonina Luca, Maria Luca, Paolo Olgiati, Raffaele Ferri, George Perry, Alessandro Serretti

{"title":"Neuropsychiatric characteristics of capgras syndrome in Alzheimer's disease in the CATIE-AD.","authors":"Antonina Luca, Maria Luca, Paolo Olgiati, Raffaele Ferri, George Perry, Alessandro Serretti","doi":"10.1080/13651501.2026.2724972","DOIUrl":"https://doi.org/10.1080/13651501.2026.2724972","url":null,"abstract":"Introduction: Capgras syndrome (CS) is a recurrent and transient delusional misidentification disorder in which an individual is firmly convinced that a familiar person has been replaced by an identical impostor. The aim of the study was to evaluate neuropsychiatric characteristics of CS in a cohort of patients with Alzheimer's disease (AD).Methods: 150 participants [84 (56.0%) women, mean age 77.4 ± 7.5 years)] were collected within the Clinical Antipsychotic Trials of Intervention Effectiveness-Alzheimer disease (CATIE-AD). According to the Neuropsychiatric Inventory, patients were classified into Capgras+ and Capgras-.Results: Fifty-five (36.7%) AD patients were Capgras+. CS was strongly associated with other misidentification syndromes including phantom boarder (p < 0.001) and misidentification of places (p < 0.001). Moreover, Capgras+ were presented more frequently with agitation (p = 0.036), depressive (p = 0.018) and anxious (p = 0.004) symptoms, and aberrant motor behaviours (p = 0.020).Conclusions: According to our findings, CS was not an 'isolated' phenomenon but rather a complex neuropsychiatric syndrome frequently associated with other misidentification syndromes and specific behavioural disturbances.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-5"},"PeriodicalIF":2.3,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroconvulsive therapy and its image: towards a balanced perspective. A response to https://pubmed.ncbi.nlm.nih.gov/41697857/ int J psychiatry clin pract. 2026 feb 16:1-3. 电休克疗法及其图像：走向平衡的视角。对https://pubmed.ncbi.nlm.nih.gov/41697857/的回应J精神病学临床实践。2026 feb 16:1-3。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-01 Epub Date: 2026-04-29 DOI: 10.1080/13651501.2026.2657050

Pia Baldinger-Melich

引用次数: 0

Evaluating social effort in schizophrenia: psychometric properties of the social effort and conscientiousness scale (SEACS) in patients with schizophrenia. 评估精神分裂症患者的社会努力：精神分裂症患者社会努力和责任心量表（SEACS）的心理测量特征。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-01 Epub Date: 2026-04-20 DOI: 10.1080/13651501.2026.2658482

Sevde Nur Karabulut, Deniz Büyükgök, Nehir Zeren, Çağla Ceren Türkoğlu, Alp Üçok, Ezgi İnce Guliyev

{"title":"Evaluating social effort in schizophrenia: psychometric properties of the social effort and conscientiousness scale (SEACS) in patients with schizophrenia.","authors":"Sevde Nur Karabulut, Deniz Büyükgök, Nehir Zeren, Çağla Ceren Türkoğlu, Alp Üçok, Ezgi İnce Guliyev","doi":"10.1080/13651501.2026.2658482","DOIUrl":"10.1080/13651501.2026.2658482","url":null,"abstract":"Background: The effort invested in establishing and maintaining social relationships is a key component of socialisation, yet it remains difficult to assess. Understanding the difficulties that individuals with schizophrenia experience in forming social connections through a self-reported assessment appears particularly important.Aims: This study aimed to adapt the Social Effort and Conscientiousness Scale (SEACS) into Turkish and examine its psychometric properties in individuals with schizophrenia.Methods: Sixty-four patients with schizophrenia and 70 healthy controls completed the SEACS-TR and related scales. Psychometric analyses included internal consistency, factor analysis, and convergent validity.Results: SEACS-TR demonstrated good internal consistency (α = .86). Using principal component analysis, we identified a three-factor solution (social initiation, connection, conscientiousness) explaining nearly 60% of the variance. A preliminary confirmatory factor analysis conducted within the same dataset supported the three-factor model with good fit (CFI = .927). Patients scored significantly lower than controls (t = 3.844, p < .001). SEACS-TR scores correlated moderately to strongly with social functioning, anhedonia, and negative symptoms.Conclusions: SEACS-TR is a reliable and valid tool for assessing social effort in schizophrenia and may inform personalised interventions.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"280-289"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clozapine underutilization in Saudi Arabia: insights from a national survey of psychiatrists and implications for clinical training and practice. 氯氮平在沙特阿拉伯的利用不足：从精神科医生的全国调查的见解和对临床培训和实践的影响。

IF 2.3 4区医学

International Journal of Psychiatry in Clinical Practice Pub Date : 2026-09-01 Epub Date: 2026-04-27 DOI: 10.1080/13651501.2026.2661356

Muath M Alqarni, Ahad R Almuallim, Yasemin Y Demiroz, Hussain Khrad, Rozan Omdah, Hanady Gouta, Ahmad S Alzahrani

{"title":"Clozapine underutilization in Saudi Arabia: insights from a national survey of psychiatrists and implications for clinical training and practice.","authors":"Muath M Alqarni, Ahad R Almuallim, Yasemin Y Demiroz, Hussain Khrad, Rozan Omdah, Hanady Gouta, Ahmad S Alzahrani","doi":"10.1080/13651501.2026.2661356","DOIUrl":"10.1080/13651501.2026.2661356","url":null,"abstract":"Objective: To examine psychiatrists' prescribing patterns, attitudes, and knowledge regarding clozapine use in Saudi Arabia, and to identify factors associated with clozapine prescribing.Methods: A cross-sectional survey was distributed to psychiatrists and trainees across Saudi Arabia between January and June 2024. The questionnaire assessed demographics, prescribing patterns, attitudes, and clinical decision-making regarding clozapine. Descriptive statistics summarised responses, and comparisons between consultants and trainees were conducted using chi-square and t-tests. Binary logistic regression was applied to identify independent predictors of clozapine prescribing.Results: Ninety-seven psychiatrists participated; 69.1% had prescribed clozapine during the previous year. Consultants were significantly more likely than trainees to prescribe clozapine (p = 0.012). The majority (79.4%) agreed that clozapine is the most effective antipsychotic, yet 71% viewed its initiation as an administrative burden. Only 42.3% reported confidence in managing side effects, and 36.1% indicated access to clozapine-specific clinics. Logistic regression showed that perceiving clozapine initiation as an administrative burden significantly reduced the likelihood of prescribing (B = -1.44, p = 0.045, OR = 0.24, 95% CI = 0.06-0.97).Conclusions: Despite high awareness of clozapine's efficacy, administrative and structural barriers continue to limit its use among psychiatrists in Saudi Arabia.","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"290-298"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0