International Journal of Psychiatry in Clinical Practice最新文献

{"title":"Adult ADHD: associated medical conditions and related factors.","authors":"Gabriele Di Salvo, Lorenzo Filippo, Camilla Perotti, Luca Pellegrini, Gianluca Rosso, Giuseppe Maina","doi":"10.1080/13651501.2025.2517050","DOIUrl":"https://doi.org/10.1080/13651501.2025.2517050","url":null,"abstract":"<p><strong>Objective: </strong>The study aims to investigate the prevalence of general medical conditions (GMCs) within a sample of adult with Attention Deficit Hyperactivity Disorder (ADHD) and to ascertain whether such comorbidities may correlate with specific socio-demographic or clinical parameters.</p><p><strong>Methods: </strong>The sample included 196 outpatients with adult ADHD. Binary logistic regression (LogReg) was used to identify explanatory variables associated with GMC.</p><p><strong>Results: </strong>Ninety-four subjects (48%) had at least one GMC. ADHD patients with GMCs showed more psychiatric family history (56.7% vs 30.9%), more comorbidities with bipolar spectrum disorders (17% vs 5.9%), and greater impairment in social functioning (67% vs 52.9%). At the LogReg analysis, only the association with psychiatric family history and comorbidity with bipolar disorder remained significant.</p><p><strong>Conclusions: </strong>We observed a high prevalence of GMC among adult ADHD outpatients. The association found between GMC and a family history of psychiatric disorders allows to hypothesise that there may be a genetic predisposition substrate to both GMC and psychiatric disorders, while the association between GMC and comorbidity with bipolar spectrum disorders can be explained by the tendency of bipolar disorder itself to be associated with GMC. It appears crucial in these patients to perform routine medical examinations and to implement a healthy lifestyle.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-5"},"PeriodicalIF":2.9,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of regressive and non-regressive autism: a study of clinical patterns and environmental risk factors in Turkey.","authors":"Nagihan Cevher Binici, Ayşe Kutlu, Çisel Yazan Songür, Hande Emine Sabah Barış","doi":"10.1080/13651501.2025.2519522","DOIUrl":"https://doi.org/10.1080/13651501.2025.2519522","url":null,"abstract":"<p><strong>Objective: </strong>This study compared clinical features, symptom severity, and prenatal/perinatal risk factors in children with regressive (ASD-R) and non-regressive autism spectrum disorder (ASD-NR) in a Turkish paediatric sample.</p><p><strong>Method: </strong>A retrospective cross-sectional study was conducted with 143 children aged 2-6 years diagnosed with ASD, grouped as ASD-R (n = 29) or ASD-NR (n = 114). Symptom severity was assessed using the CARS, AuBC, and ABC. Data on prenatal and perinatal factors, epilepsy, and parental age were collected.</p><p><strong>Results: </strong>No significant differences were found in CARS, AuBC, or total ABC scores, except for higher lethargy/social withdrawal scores in the ASD-NR group. Prenatal and perinatal risk factors and epilepsy prevalence were similar. However, parental ages at birth were significantly higher in the ASD-R group. Logistic regression did not yield significant predictors of regression.</p><p><strong>Conclusion: </strong>The findings suggest that prenatal and perinatal factors may influence developmental regression in ASD when interacting with genetic vulnerability. Longitudinal studies are needed to clarify the role of early environmental exposures and epigenetic mechanisms in regression patterns.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perimenopausal depression: etiology, clinical characteristics, and the role of traditional Chinese medicine.","authors":"Ling Wang, Yunyun Liu, Xiaoying Qi, Hong Luo","doi":"10.1080/13651501.2025.2501250","DOIUrl":"https://doi.org/10.1080/13651501.2025.2501250","url":null,"abstract":"<p><strong>Background: </strong>Perimenopausal depression (PMD) is a common condition among women transitioning to menopause, characterised by various physical and psychological symptoms.</p><p><strong>Method: </strong>This review explores the aetiology, clinical manifestations, and latest treatment approaches for PMD, highlighting the complexity and multi-factorial nature of the disorder.</p><p><strong>Outcome: </strong>Key treatment strategies include hormone replacement therapy (HRT), antidepressants, traditional Chinese medicine (TCM), cognitive-behavioral therapy (CBT), and lifestyle modifications.</p><p><strong>Conclusion: </strong>Comprehensive and individualised treatment plans are essential for effectively managing PMD and improving the quality of life for affected women.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life in patients with: A longitudinal study with 10 years of follow-up.","authors":"Alejandra Caqueo-Urízar, Felipe Ponce-Correa, J Francisco Santibáñez-Palma, Alfonso Urzúa, Laurent Boyer","doi":"10.1080/13651501.2025.2517049","DOIUrl":"https://doi.org/10.1080/13651501.2025.2517049","url":null,"abstract":"<p><strong>Background: </strong>Quality of life (QoL) in patients with Schizophrenia has become one of the most important outcome measures in long-term treatment; however, in the Latin American context, longitudinal research that analyzes its trajectories over time and its relationship with clinical and sociodemographic aspects is still scarce. The aim of this study was to longitudinally evaluate QoL in conjunction with psychotic symptomatology, internalised stigma, social cognition, premorbid adjustment, and years of untreated psychosis in a sample of patients with a diagnosis of Schizophrenia in Northern Chile.</p><p><strong>Method: </strong>A total of 26 patients were able to complete the 10-year follow-up of measures and predictors of stigma, which were evaluated in Public Outpatient Mental Health Centres in the city of Arica between March-July 2012 and March-July 2022. The results show that QoL trajectories improve over time, especially in aspects such as family relationships, autonomy and resilience. On the other hand, depressive symptoms, self-stigma and premorbid adjustment were significant predictors of follow-up measures of QoL.</p><p><strong>Discussion: </strong>These results underscore the importance of overcoming stigma and depressive symptomatology to improve the QoL of patients with Schizophrenia. Also, the results yielded that premorbid successful psychosocial functioning and experiences are a significant predictor of QoL.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the role of subthreshold autistic traits on body image uneasiness: a study among Italian female with eating disorders.","authors":"Clara Lombardo, Maria Catena Silvestri, Fiammetta Iannuzzo, Fabrizio Turiaco, Giovanni Genovese, Maria Rosaria Anna Muscatello, Antonio Bruno, Carmela Mento, Gianluca Pandolfo","doi":"10.1080/13651501.2025.2517843","DOIUrl":"https://doi.org/10.1080/13651501.2025.2517843","url":null,"abstract":"<p><strong>Objective: </strong>The present study evaluate the presence of subthreshold autistic traits, assess the level of body image dissatisfaction, and explore their potential association in female patients with eating disorders.</p><p><strong>Method: </strong>The study used the Adult Autism Subthreshold Spectrum - AdAS and the Body Uneasiness Test - BUT to identify autistic traits that predict body image distress, applying linear and stepwise regression.</p><p><strong>Results: </strong>The sample consisted of 49 female patients with eating disorders with a mean duration of illness of 4 years. Regression analysis indicated that BUT 'Weight Phobia' factor was positively associated with AdAS 'Non-Verbal communication' and 'Inflexibility and adherence to routine' domains, BUT 'Body Image Concerns' factor was associated with AdAS 'Non-Verbal communication' and 'Inflexibility and adherence to routine' domains. BUT 'Compulsive Self-Monitoring' factor was associated with AdAS 'Inflexibility and adherence to routine' domain and, finally BUT 'Depersonalization' factor was positively associated with AdAS 'Hyper- and hypo reactivity to sensory input'. The average AdAS score is 73.8 (± SD 22.8).</p><p><strong>Conclusions: </strong>The study highlights that subthreshold autistic traits may play a role in altering body image in patients with eating disorders, possibly due to altered sensory perception. Further research is needed to explore causes and therapies.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term association of Ramadan fasting and depression score: results from MASHAD Cohort Study.","authors":"Habibollah Esmaily, Susan Darroudi, Maryam Saberi-Karimian, Mobina Imannezhad, Gordon A Ferns, Mohammad Reza Mohammad Taghizadeh Sarabi, Majid Ghayour-Mobarhan, Maryam Alinezhad-Namaghi","doi":"10.1080/13651501.2025.2489944","DOIUrl":"10.1080/13651501.2025.2489944","url":null,"abstract":"<p><strong>Background: </strong>Depression is a mood-related disease that affects a person's life. The effects of Ramadan fasting on mental health, including depression, have been investigated in a few previous studies. So, this study examines the long-term association between fasting during Ramadan and depression.</p><p><strong>Methods: </strong>This was a retrospective cohort study based on the data of the MASHAD (Mashhad stroke and heart atherosclerotic disorder) study. Depression was considered as scores >13 using Beck's depression inventory II (BDI II). The study subjects included three groups of healthy, people who developed depression during follow-up (Dep1-, Dep2+), and people who suffered from depression during study (Dep1+, Dep2+).</p><p><strong>Results: </strong>A total of 8609 individuals completed the study. There was no significant association between fasting throughout life and Ramadan with the incidence of depression (<i>p</i> > 0.05). However, an earlier age of initiation for the first experience of Ramadan fasting was associated with 8.4% higher incidence of depression (OR: 0.916, CI (0.889-0.944)) in Dep1-, Dep2 + group and 10.7% for Dep1+, Dep2+ (OR: 0.893, CI: (0.861-0.925)) (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Fasting during Ramadan may not be associated with the incidence of depression, but the lower age of first Ramadan fasting could be related to depression.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"66-73"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of children's emotional and behavioural problems and parents' psychological distress in child and adolescent psychiatric clinic Hospital Sultan Abdul Aziz Shah.","authors":"Ruziana Masiran, Kit-Aun Tan, Muhammad Afiq Ismanizan, Nordiana Alina Roslee, Priyadarshika Prabaharan","doi":"10.1080/13651501.2025.2500543","DOIUrl":"10.1080/13651501.2025.2500543","url":null,"abstract":"<p><strong>Objective: </strong>There is a growing concern regarding the increasing trend of emotional and behavioural problems (EBP) in children, alongside rising mental health challenges among Malaysian parents. This study aims to delineate the prevalence of EBP in children attending the child and adolescent psychiatric (CAP) clinic at Hospital Sultan Abdul Aziz Shah and assess the levels of psychological distress in their parents.</p><p><strong>Methods: </strong>In this cross-sectional study, 125 parents assessed the severity of their children's EBP and their own mental health using validated self-administered questionnaires.</p><p><strong>Results: </strong>The prevalence of EBP among children was 48.0%, while the prevalence of depression, anxiety, and stress among their parents was 32.8%, 45.6%, and 32.8%, respectively.</p><p><strong>Conclusion: </strong>In line with global literature, this study emphasises the critical need to address the mental health of parent-child dyads <i>via</i> the implementation of integrated services that manage these intertwined issues.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"91-95"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a predictive model for readmission of major depressive disorder patients with suicide attempts.","authors":"Xinmei Hao, Ligang Wang, Liqiang Dou, Yingying Huang, Jun Chen, Ping Sun","doi":"10.1080/13651501.2025.2510244","DOIUrl":"10.1080/13651501.2025.2510244","url":null,"abstract":"<p><p>The study aimed to investigate the determinants associated with readmission in first-hospitalised major depressive disorder (MDD) patients with suicide attempts. The study included a cohort of 3977 patients diagnosed with MDD, as retrieved from the hospital information system (HIS). The data were split into a training set and a validation set using R software. To develop a stepwise regression model, the multivariate logistic analysis included significant factors (p threshold <0.2 in univariate analysis).(1) There was a significant difference in the incidence of readmission between first-hospitalised MDD patients with suicide attempts and those without; (2) Length of stay, course of disease, somatic symptoms, psychosis symptoms, anxiety symptoms, alcohol/tobacco dependence, family history of psychiatric disease, continued use of antidepressants combined with antipsychotics or not after discharge, and total bilirubin (TBIL) were included in these variables to build a predictive model in R software; (3) The area under the curve (AUC) was 0.783 for the training set and 0.778 for the validation set. The Hosmer-Lemesho (H-L) test for calibration was <i>p</i> = 0.3521 for the training set and <i>p</i> = 0.8497 for the validation set. The study revealed a significantly increased risk of readmission in first-hospitalised MDD patients with suicide attempts compared to their counterparts.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"82-90"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive analysis of medical malpractice claims related to psychotropic substances: which psychotrop substances should be considered more medico-legal cautious?","authors":"Muhammed Emin Boylu, Caner Beşkoç, Yusuf Atan, Muhammed Oduncu, Hızır Aslıyüksek, Şenol Turan","doi":"10.1080/13651501.2025.2496504","DOIUrl":"10.1080/13651501.2025.2496504","url":null,"abstract":"<p><strong>Introduction: </strong>Psychotropic drugs are commonly employed in the treatment of various psychiatric disorders, yet they carry a number of risks due to their potential side effects and interactions with other drugs. Some medical errors in the prescribing of psychotropic medication may have adverse consequences for patients, which may result in physical harm or even death. The objective of this study is to define the processes to be considered by investigating medical malpractice claims related to psychotropic drug treatment.</p><p><strong>Method: </strong>A retrospective examination was conducted of the sociodemographic and clinical characteristics of medical malpractice cases alleged and reported by the relevant boards of the Turkish Council of Forensic Medicine (2nd Specialised Board, 7th Specialised Board, 8th Specialised Board, and 3rd Supreme Board) between 2013 and 2022.</p><p><strong>Results: </strong>The majority of cases were male (72%), with an average age of 33.10 ± 16.63 years. The most common diagnosis was schizophrenia (28%), and the most frequent malpractice claims involved the effects of antipsychotic medications (50%). The most common side effects leading to claims were cardiac side effects (34%) in cases that resulted in death (<i>p</i> < 0.001) and extrapyramidal system side effects in other cases (14%) (<i>p</i> < 0.001). It was observed that 29 cases (58%) resulted in death. Antidepressants were more often claimed for causing deaths (<i>p</i> = 0.045), while mood stabilisers were more often claimed for resulting in injuries (<i>p</i> = 0.039). In 81% of non-fatal cases, the clinical side effect in question was determined to be related to the treatment (<i>p</i> = 0.002) and was managed appropriately as a complication (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Psychotropic drugs can carry serious risks, especially cardiac and extrapyramidal side effects. Careful monitoring and management of these medicines are essential for patient outcomes and safety. These side effects may lead to medical error claims in some cases; however, when managed correctly, they are not considered malpractice.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"57-65"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotion regulation difficulties are associated with psychosocial functioning via trait anxiety levels in remitted bipolar disorder patients.","authors":"Sezgi İlke Danacı Sezgin, Tayfun Turan, Akif Asdemir, Saliha Özsoy","doi":"10.1080/13651501.2025.2492159","DOIUrl":"10.1080/13651501.2025.2492159","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to determine the effects of anxiety levels and emotion dysregulation on each other and their effects on psychosocial functioning in remitted BD patients.</p><p><strong>Methods: </strong>Sixty-six patients with BD and 38 healthy controls were included in this study. All the patients were assessed with the Hamilton Depression Rating Scale, the Young Mania Rating Scale, the Bipolar Disorder Functioning Questionnaire, the State-Trait Anxiety Inventory (STAI) and the Difficulties in Emotion Regulation Scale (DERS). Healthy controls were only assessed with the STAI and the DERS.</p><p><strong>Results: </strong>STAI and DERS scores were significantly higher in the patient group than in the control group. Higher scores of STAI and DERS were found to be associated with lower functionality in the patient group. The trait anxiety scores explained 22% of the variance in the psychosocial functionality scores of the patients while the total DERS score explained 51.5% of the variance in the trait anxiety scores. Patients on lithium treatment had less difficulty in regulating their emotions than those on valproic acid treatment.</p><p><strong>Conclusions: </strong>In light of these findings, planning interventions for emotion regulation difficulties during the management of patients would reduce anxiety levels and contribute to improving patients' psychosocial functionality.</p>","PeriodicalId":14351,"journal":{"name":"International Journal of Psychiatry in Clinical Practice","volume":" ","pages":"51-56"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}