International Journal of Food Sciences and Nutrition最新文献_第2页

Effects of aerobic exercise and antioxidant micronutrients on leptin levels in pregnancy: a sub-analysis from a double-blinded randomised controlled trial. 有氧运动和抗氧化微量营养素对妊娠期瘦素水平的影响：一项双盲随机对照试验的亚分析

IF 3.3 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-09-01 Epub Date: 2025-07-09 DOI: 10.1080/09637486.2025.2525905

Milton Fabián Suárez-Ortegón, José Guillermo Ortega-Avila, Isabella Echeverri, Julio Cesar Mateus, Mildrey Mosquera

{"title":"Effects of aerobic exercise and antioxidant micronutrients on leptin levels in pregnancy: a sub-analysis from a double-blinded randomised controlled trial.","authors":"Milton Fabián Suárez-Ortegón, José Guillermo Ortega-Avila, Isabella Echeverri, Julio Cesar Mateus, Mildrey Mosquera","doi":"10.1080/09637486.2025.2525905","DOIUrl":"10.1080/09637486.2025.2525905","url":null,"abstract":"Hyperleptinemia is associated with pregnancy complications. We assessed the effects of aerobic exercise, antioxidant micronutrient supplementation (AMS), and their combination on leptin levels during pregnancy. Healthy pregnant women were randomized to four groups: exercise (n = 19), AMS (zinc/magnesium/tocopherol/vitamin C/niacin) (n = 19), exercise plus AMS (n = 19), and controls (n = 20). Leptin levels were measured at 16-20 and 32-36 gestational weeks. Fat mass percentage (FM%) and high-sensitivity C-reactive protein (hs-CRP) were secondary outcomes. No significant baseline differences were observed across groups. Post-intervention leptin levels were significantly lower in the exercise group compared to controls [Geometric mean (95% CI): 24 (20-28.8) vs. 33.8 (26.9-42.3), p = 0.028]. No significant differences were found for the other interventions or for FM% and hs-CRP. Leptin increased in all groups (p < 0.05) except the exercise group (p = 0.682). In conclusion, aerobic exercise prevented leptin elevation during pregnancy, independently of fat mass changes. AMS attenuated this benefit when combined with exercise.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"624-633"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Southern Italian Children, Adolescents and paRents cOhort Study on nutrition and health: protocol of the ICARO Study. 意大利南部儿童、青少年和父母营养与健康队列研究：ICARO研究方案。

IF 3.3 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-09-01 Epub Date: 2025-07-09 DOI: 10.1080/09637486.2025.2523393

Marialaura Bonaccio, Emilia Ruggiero, Giuseppe Grosso, Augusto Di Castelnuovo, Giuseppe Di Costanzo, Marika Dello Russo, Annarita Formisano, Fabio Lauria, Nadia Paladino, Giovanni de Gaetano, Licia Iacoviello

{"title":"The Southern Italian Children, Adolescents and paRents cOhort Study on nutrition and health: protocol of the ICARO Study.","authors":"Marialaura Bonaccio, Emilia Ruggiero, Giuseppe Grosso, Augusto Di Castelnuovo, Giuseppe Di Costanzo, Marika Dello Russo, Annarita Formisano, Fabio Lauria, Nadia Paladino, Giovanni de Gaetano, Licia Iacoviello","doi":"10.1080/09637486.2025.2523393","DOIUrl":"10.1080/09637486.2025.2523393","url":null,"abstract":"In Italy, around 30% of children and adolescents are overweight or obese, with higher rates in the South. Parental dietary habits influence children's eating behaviours, yet most studies focus on food composition without considering the level of food processing. The Nova classification categorises foods by processing levels, suggesting that food processing may affect health beyond nutritional content. Ultra-processed foods (UPFs), such as sugary drinks and packaged snacks, are calorie-dense and contain cosmetic food additives. High UPF consumption is linked to obesity, chronic diseases, and poor cognitive development in children. However, no comprehensive up-to-date assessment of UPF consumption among Italian children exists. To address this gap, the ICARO Study was launched in Southern Italy as a web-based cohort of children, adolescents, and their parents. This study aims to evaluate UPF consumption and its correlates, and assess the impact of a nutrition education intervention on reducing UPF intake at the family level.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"601-610"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The bidirectional association between incidence of depression and obesity in Brazilian graduates (CUME study): a 6-year prospective study. 巴西大学毕业生抑郁和肥胖发生率的双向关联（CUME研究）：一项为期6年的前瞻性研究。

IF 3.3 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-09-01 Epub Date: 2025-08-08 DOI: 10.1080/09637486.2025.2543252

Arieta Carla Gualandi Leal, Josefina Bressan, Leidjaira Juvanhol Lopes, Adriano Marçal Pimenta, Helen Hermana Miranda Hermsdorff

{"title":"The bidirectional association between incidence of depression and obesity in Brazilian graduates (CUME study): a 6-year prospective study.","authors":"Arieta Carla Gualandi Leal, Josefina Bressan, Leidjaira Juvanhol Lopes, Adriano Marçal Pimenta, Helen Hermana Miranda Hermsdorff","doi":"10.1080/09637486.2025.2543252","DOIUrl":"10.1080/09637486.2025.2543252","url":null,"abstract":"To evaluate the bidirectional relationship between the incidence of depression and obesity in Brazilian graduates. This 6-year longitudinal follow-up study included 3,426 participants from the CUME study in assessing the incidence of obesity and 3,414 participants in assessing the incidence of depression. Risk ratios were estimated and the interaction by sex was tested using the multiplicative method. After an average follow-up of 2.13 years, 387 incident cases of depression and 216 cases of obesity were identified. When stratified by sex, women with an initial diagnosis of depression were at increased risk of developing obesity over time (HR: 2.14; 95% CI: 1.47 - 3.11). The association between initial obesity and incidence of depression was also positive, but only for men (HR: 1.82; 95% CI 1.05 - 3.16). As conclusion, there is bidirectional association for incidence of depression and obesity over time and the risks of developing these diseases are associated differently by sex.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"646-653"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimated dietary intake of polyphenols from culinary herbs and herbal infusions in the HYDRIA survey. 在HYDRIA调查中，从烹饪草药和草药输液中估计的膳食多酚摄入量。

IF 3.3 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1080/09637486.2025.2556816

Eleni Peppa, Ekaterina-Michaela Tomou, Georgia Vourli, Antonia Trichopoulou

{"title":"Estimated dietary intake of polyphenols from culinary herbs and herbal infusions in the HYDRIA survey.","authors":"Eleni Peppa, Ekaterina-Michaela Tomou, Georgia Vourli, Antonia Trichopoulou","doi":"10.1080/09637486.2025.2556816","DOIUrl":"10.1080/09637486.2025.2556816","url":null,"abstract":"This study evaluates the daily intake of polyphenols from culinary herbs and herbal infusions among the Greek adult population through the HYDRIA survey. The polyphenol content was assessed through the Phenol-Explorer database. The mean intake of total polyphenols from culinary herbs was 3.30 mg/day, and 70.35 mg/day from herbal infusions. Phenolic acids were the primary contributors from herbal infusions, accounting for 63.92 mg/day, with hydroxycinnamic acids making up the majority (54.43 mg/day). Flavonoids, particularly flavonols, were the most consumed polyphenol class from culinary herbs across all sexes and age groups. The most prevalent phenolic acids found in herbal infusions were those derived from mountain tea. Men aged 18-64 years old had the highest total polyphenol intake from herbal infusions, while women aged 65+ had the lowest intake. These findings provide a comprehensive overview of polyphenol consumption from culinary herbs and herbal infusions in Greece and can offer valuable insights for future nutritional research.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"666-674"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Faecal short-chain fatty acids and nutritional factors in Thai adults with hypercholesterolaemia compared to normocholesterolemic subjects. 泰国成人高胆固醇血症患者与正常胆固醇血症患者的粪便短链脂肪酸和营养因子比较

IF 3.3 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-09-01 Epub Date: 2025-07-02 DOI: 10.1080/09637486.2025.2525901

Parunya Thiyajai, Pimwatchanok Trangcasanchai, Phornthip Thapprathum, Thananya Soonkum, Pimnapanut Sridonpai, Sarunya Kitdumrongthum, Kunchit Judprasong, Wantanee Kriengsinyos, Aree Prachansuwan

{"title":"Faecal short-chain fatty acids and nutritional factors in Thai adults with hypercholesterolaemia compared to normocholesterolemic subjects.","authors":"Parunya Thiyajai, Pimwatchanok Trangcasanchai, Phornthip Thapprathum, Thananya Soonkum, Pimnapanut Sridonpai, Sarunya Kitdumrongthum, Kunchit Judprasong, Wantanee Kriengsinyos, Aree Prachansuwan","doi":"10.1080/09637486.2025.2525901","DOIUrl":"10.1080/09637486.2025.2525901","url":null,"abstract":"Previous studies have highlighted differences in faecal short-chain fatty acids (SCFAs) between hypercholesterolemic (HC) and normocholesterolemic (NC) individuals; however, the impact of nutritional factors on SCFAs remains underexplored. This cross-sectional observational study involved 42 HC and 38 NC Thai adults and examined faecal SCFA concentrations and their associations with nutritional factors. Aliphatic (acetic, propionic, butyric acids) and branched (isobutyric and isovaleric acids) SCFAs were analysed. Although NC participants exhibited higher aliphatic and total SCFAs than HC participants, these differences were insignificant. Carbohydrate intake was positively associated with acetic and propionic acid, in the NC group. Sugar intake was negatively correlated with isobutyric and isovaleric acids in the NC group but positively correlated in the HC group. These findings suggest less efficient sugar and carbohydrate fermentation in the HC group, potentially affecting SCFA profiles. Future studies should investigate gut microbiota composition, bile acid secretion and gut pH as contributing factors.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"611-623"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimating β-casomorphin-7 exposure from milk and dairy product consumption: a comprehensive assessment for the European population. 估计牛奶和乳制品消费中β-酪啡肽-7的暴露：对欧洲人口的综合评估。

IF 3.5 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-08-01 Epub Date: 2025-07-01 DOI: 10.1080/09637486.2025.2521298

Francesca Danesi, Filippo Rossi, Giulia Leni, Giorgia Antonelli, Alessandra Bordoni, Terenzio Bertuzzi, Mattia Santoni, Davide Risso, Federico Canzoneri, Roberto Menta, Margherita Dall'Asta

{"title":"Estimating β-casomorphin-7 exposure from milk and dairy product consumption: a comprehensive assessment for the European population.","authors":"Francesca Danesi, Filippo Rossi, Giulia Leni, Giorgia Antonelli, Alessandra Bordoni, Terenzio Bertuzzi, Mattia Santoni, Davide Risso, Federico Canzoneri, Roberto Menta, Margherita Dall'Asta","doi":"10.1080/09637486.2025.2521298","DOIUrl":"10.1080/09637486.2025.2521298","url":null,"abstract":"β-Casomorphin-7 (BCM-7), a heptapeptide derived from β-casein hydrolysis, has gained attention for its potential role in gastrointestinal discomfort and certain diseases, yet its effects remain controversial. This study aimed to provide the first reliable estimation of BCM-7 exposure for low, medium and high consumers of milk and dairy products in the European population. We developed a database on BCM-7 released after simulated digestion, combining literature review and direct analysis of milk and selected dairy products. Using European food consumption data, we estimated BCM-7 daily exposure for adults (132-2541 μg), adolescents (163-2594 μg) and children (200-2357 μg). Milk emerged as the most significant source of BCM-7 exposure across all population groups. Statistical analysis revealed differences in exposure levels between adults and children at medium consumption levels. This work provides the first comprehensive estimation of dietary BCM-7 exposure, laying the groundwork for future research on its potential health effects.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"571-580"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When knowledge is not enough: understanding the barriers to sustainable food choices in Italy. 当知识不够时：了解意大利可持续食品选择的障碍。

IF 3.5 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-08-01 Epub Date: 2025-06-08 DOI: 10.1080/09637486.2025.2515109

Vittoria Aureli, Alessandra Nardi, Nadia Palmieri, Daniele Peluso, Laura Rossi

{"title":"When knowledge is not enough: understanding the barriers to sustainable food choices in Italy.","authors":"Vittoria Aureli, Alessandra Nardi, Nadia Palmieri, Daniele Peluso, Laura Rossi","doi":"10.1080/09637486.2025.2515109","DOIUrl":"10.1080/09637486.2025.2515109","url":null,"abstract":"The actual food system negatively impacts human health and the environment. To promote sustainable food consumption, a cross-sectional survey of 815 Italian adults, representative for age, gender, and geographical areas, explored consumer perceptions and purchasing barriers. Correspondence and cluster analysis were applied. Most respondents identified sustainable foods as having low environmental impact (88.6%), being healthy (81.3%), and locally sourced (81.2%). However, high prices and unclear labelling emerged as key obstacles. The cluster analysis identified four consumer groups. Notably, even the group aware of sustainability issues (Aware consumers with barriers - Cluster 2) still struggled to make sustainable choices due to persistent obstacles. Conversely, a small segment (Ditched consumers - Cluster 1), despite high socio-economic and educational status, showed no interest in sustainability. These results highlight the complex nature of barriers to sustainable consumption, shaped by diverse sociodemographic factors. Tailored strategies are needed to overcome these obstacles and support more sustainable consumer behavior.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"560-570"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adherence to mediterranean diet attenuates the link between impaired fasting glucose and 20-year cumulative incidence of type 2 diabetes: the ATTICA cohort study (2002-2022). ATTICA队列研究（2002-2022）：坚持地中海饮食可减弱空腹血糖受损与20年2型糖尿病累积发病率之间的联系。

IF 3.5 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-08-01 Epub Date: 2025-06-29 DOI: 10.1080/09637486.2025.2525899

Ioanna Kechagia, Fotios Barkas, Evangelos Liberopoulos, Polyxeni Kaloudi, Christina Chrysohoou, Petros P Sfikakis, Costas Tsioufis, Christos Pitsavos, Demosthenes Panagiotakos

{"title":"Adherence to mediterranean diet attenuates the link between impaired fasting glucose and 20-year cumulative incidence of type 2 diabetes: the ATTICA cohort study (2002-2022).","authors":"Ioanna Kechagia, Fotios Barkas, Evangelos Liberopoulos, Polyxeni Kaloudi, Christina Chrysohoou, Petros P Sfikakis, Costas Tsioufis, Christos Pitsavos, Demosthenes Panagiotakos","doi":"10.1080/09637486.2025.2525899","DOIUrl":"10.1080/09637486.2025.2525899","url":null,"abstract":"The aim of the present study was to evaluate the association between impaired fasting glucose and the 20-year cumulative incidence of type 2 diabetes (T2D), and the role of lifestyle habits, in the ATTICA cohort study (2002-2022). The present analysis was based on 2000 individuals free of T2D at baseline examination (age 43 ± 13 years; 51% women), 773 (39%) had IFG defined by fasting glucose 100-125 mg/dL and HbA1c 5.7-6.4%. Sociodemographic, anthropometric, lifestyle, and clinical parameters were collected at baseline and follow-up examinations. The 20-year cumulative incidence of T2D was 347 out of 773 (45%) participants with IFG. Male sex [RR 1.82, 95%CI (1.36, 2.43)], overweight [RR 6.3, 95%CI (3.7, 10.5)], obesity [RR 5.3, 95%CI (2.5, 11.3)], hypercholesterolaemia [RR 1.71, 95%CI (1.28, 2.28)], smoking [RR 1.67, 95%CI (1.14, 2.44)] and adherence to Mediterranean diet (high vs. low) [RR 0.41, 95%CI (0.26, 0.65)], were significantly associated with the development of T2D in the subjects with IFG, during the 20-year of follow-up. IFG significantly increases the risk of T2D, with male sex, obesity, hypercholesterolaemia, and smoking as key risk factors. Adherence to the Mediterranean diet and weight management were protective, in preventing diabetes progression.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"581-591"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144527906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of berry consumption on cardiometabolic risk factors in patients with metabolic syndrome: a systematic review and meta-analysis of randomised controlled trials. 浆果食用对代谢综合征患者心脏代谢危险因素的影响：随机对照试验的系统回顾和荟萃分析

IF 3.5 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-08-01 Epub Date: 2025-05-28 DOI: 10.1080/09637486.2025.2510358

Mohammad Amin Mohammadi, Ali Ebrahimi Dabagh, Shirin Hassanizadeh, Gholamreza Askari, Mohammad Bagherniya, Amirhossein Sahebkar

{"title":"Effects of berry consumption on cardiometabolic risk factors in patients with metabolic syndrome: a systematic review and meta-analysis of randomised controlled trials.","authors":"Mohammad Amin Mohammadi, Ali Ebrahimi Dabagh, Shirin Hassanizadeh, Gholamreza Askari, Mohammad Bagherniya, Amirhossein Sahebkar","doi":"10.1080/09637486.2025.2510358","DOIUrl":"10.1080/09637486.2025.2510358","url":null,"abstract":"The current study explored the effect of berry consumption on metabolic syndrome (MetS) factors. After full screening, 14 trials were selected for final analysis, involving 327 intervention and 284 control subjects with MetS. Berry consumption significantly increased HDL-C (WMD: 1.771 mg/dL, 95% CI: 1.415-2.128) without affecting LDL-C, TC, TG or leptin levels. BMI, waist circumference, systolic and diastolic BP, TNF-α, IL-6, CRP, adiponectin, HbA1C, HOMA-IR, glucose and insulin remained unaffected. The subgroup analysis showed that interventions <12 weeks resulted in a significant increase in HDL-C levels and a significant decrease in serum TG levels. On the other hand, reductions in IL-6 and glucose levels were observed in interventions >12 weeks. It was also shown that CRP and HDL-C improvements were seen only in studies that included more than 50 participants. Berry consumption may improve HDL-C, glucose, IL-6 and CRP, supporting its inclusion in dietary strategies for managing MetS.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"495-516"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lactobacillus kefiranofaciens and its enhancement effect on the anti-inflammatory function of CII/Gln in MIA-induced osteoarthritis by protecting the intestinal barrier and gut microecology. 乳杆菌kefiranofaciens及其通过保护肠道屏障和肠道微生态增强mia诱导骨关节炎CII/Gln抗炎功能的作用

IF 3.5 2区农林科学

International Journal of Food Sciences and Nutrition Pub Date : 2025-08-01 Epub Date: 2025-05-22 DOI: 10.1080/09637486.2025.2508173

Longgang Jia, Jiahu Yuan, Yu Chen, Peixin Liang, Jiangtao Wu, Yufeng Xie, Xiaojia Bai, Yanping Wang, Weitao Geng

{"title":"Lactobacillus kefiranofaciens and its enhancement effect on the anti-inflammatory function of CII/Gln in MIA-induced osteoarthritis by protecting the intestinal barrier and gut microecology.","authors":"Longgang Jia, Jiahu Yuan, Yu Chen, Peixin Liang, Jiangtao Wu, Yufeng Xie, Xiaojia Bai, Yanping Wang, Weitao Geng","doi":"10.1080/09637486.2025.2508173","DOIUrl":"10.1080/09637486.2025.2508173","url":null,"abstract":"Osteoarthritis (OA) is a globally chronic disease affecting middle-aged and elderly individuals, with growing evidences implicating gut microbiota in its pathogenesis. Lactobacillus kefiranofaciens ZW3 (ZW3) shows potential in modulating gut microbiota, protecting intestinal barrier, and regulating immunity. This study explored the therapeutic effects of ZW3, alone and combined with CII/Gln, using a monoiodoacetate (MIA)-induced OA model. Results indicated that ZW3 significantly mitigated cartilage damage and inflammation alone or combined with CII/Gln, possibly by improving intestinal integrity, reduced oxidative stress, and regulated MMPs expression. 16S rDNA sequencing showed ZW3, especially with CII/Gln, increased beneficial bacteria of Ruminococcaceae and Lachnospiraceae abundances. Furthermore, ZW3 or with CII/Gln elevated SCFAs levels in intestinal contents in OA rats. These findings propose a novel probiotic-based strategy, potentially combined with functional foods, for OA intervention and treatment.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"530-543"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0