International Journal of Implant Dentistry最新文献

{"title":"The surface-agnostic advantage for peri-implant health: UV photofunctionalization as a positive-sum strategy for biofilm suppression and soft-tissue barrier-a systematic review with qualitative synthesis.","authors":"Keiji Komatsu, Jasper Kim, Nicholas Her, Ryan Alpers, Natsumi Saito, Rune Shibata, Irina Fedorowicz, Sei Jin Kim, Naryung Kim, Tammy Lu, Andrew Tran, Jisub Lim, Wakako Sakaguchi, Takuma Sato, Shugo Haga, Takanori Matsuura, Wonhee Park, Takahiro Ogawa","doi":"10.1186/s40729-026-00695-1","DOIUrl":"10.1186/s40729-026-00695-1","url":null,"abstract":"<p><strong>Purpose: </strong>Long-term dental implant success depends on a biologic \"race to the surface,\" in which osteogenic cells, peri-implant soft-tissue cells, and bacterial pathogens compete for early dominance at the implant-tissue interface. Because implant surface design is often optimized for one objective at the expense of another (e.g., micro-roughness to accelerate osteoconductivity but with increased plaque-retention risk; relatively smooth transmucosal surfaces to discourage bacterial attachment despite uncertainty regarding optimal soft-tissue integration), strategies that enhance peri-implant health without forcing topographical trade-offs are needed. Ultraviolet (UV) photofunctionalization-by removing storage-acquired hydrocarbons (\"biological aging\") and converting surfaces to a high-energy, superhydrophilic state-has been proposed as a chairside, topography-preserving approach to improve interfacial biology. This systematic review evaluates whether UV photofunctionalization of titanium and zirconia surfaces provides clinically relevant advantages for (1) reduction of bacterial attachment and biofilm formation, (2) peri-implant soft-tissue responses relevant to mucosal sealing, and (3) human clinical outcomes.</p><p><strong>Methods: </strong>After systematic literature search, screening and full-text evaluation, a total of 34 articles, including 9 bacterial/biofilm, 13 soft-tissue (1 overlapping between bacterial and soft-tissue), and 13 clinical studies were selected. Findings were synthesized qualitatively with attention to protocol heterogeneity (UV wavelength band, exposure duration, device configuration, and material and surface types).</p><p><strong>Results: </strong>Across experimental models, UV photofunctionalization most consistently reduced early bacterial attachment and/or early biofilm accumulation across several titanium surface topographies, supporting an early anti-adhesive and biofilm-suppressive phenotype. Soft-tissue studies generally demonstrated enhanced fibroblast/epithelial attachment, spreading, and functional behaviors relevant to sealing on both titanium and zirconia, although the optimal underlying topography for soft-tissue integration remains unresolved. Clinically, the most consistent signal was accelerated and enhanced implant stability development, while selected studies also suggested favorable trends in peri-implant soft-tissue parameters and/or crestal bone maintenance. However, clinical outcomes remained variable and were limited by heterogeneity in UV protocols, surface systems, endpoints, and follow-up duration.</p><p><strong>Conclusions: </strong>UV photofunctionalization can be conceptualized as a surface-agnostic physicochemical reactivation technology: a topography-preserving enhancement that restores high surface energy and favorable surface chemistry without altering the underlying surface architecture. Current evidence for this concept is strongest for titanium, whereas supportive e","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13291283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148271243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement accuracy of dental cone-beam computed tomography for assessing submillimeter distances between implant and mandibular canal: a phantom study.","authors":"Hozumi Yoshihara, Eiichi Honda, Yoshizo Matsuka","doi":"10.1186/s40729-026-00694-2","DOIUrl":"10.1186/s40729-026-00694-2","url":null,"abstract":"<p><strong>Purpose: </strong>Accurate assessment of the distance between dental implants and the mandibular canal is essential for preventing nerve injury. Although cone-beam computed tomography (CBCT) is widely used for implant planning, its accuracy in resolving submillimeter distances remains uncertain. This study evaluated the measurement accuracy of CBCT for assessing distances below 1.0 mm.</p><p><strong>Methods: </strong>A custom phantom enabling 0.0-1.0 mm implant-canal distances in 0.1-mm increments was developed. CBCT images were acquired at varying distances, positional shifts (X, Y, Z), and tube voltages. Five dentists involved in implant treatment measured the implant-canal distances using medical-grade and general-purpose monitors. Measurement error and contributing imaging factors were statistically analyzed.</p><p><strong>Results: </strong>CBCT did not reliably distinguish distances ≤ 0.4 mm, with the greatest instability observed at 0.3 mm (interquartile range = 0.121). Although a linear trend was observed from 0.1 to 0.4 mm, variability exceeded clinically acceptable limits. For distances ≥ 0.5 mm, reproducibility was high, but CBCT consistently underestimated the true gap by 0.2-0.3 mm. The central field of view produced the most stable measurements, whereas accuracy decreased with off-center positioning. Tube voltage and monitor type had minimal influence on measurement accuracy.</p><p><strong>Conclusions: </strong>CBCT cannot accurately identify implant-canal distances ≤ 0.4 mm, which may directly affect clinical risk assessment. Even for distances ≥ 0.5 mm, CBCT underestimates the true distance by 0.2-0.3 mm. These findings provide practical guidance for setting safe margins in implant planning and postoperative evaluation.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13385543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148194560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resorbable scaffolds for alveolar ridge augmentation procedures: A systematic review.","authors":"Marcus Seiler, Alessandro Cucchi, Markus Tröltzsch, Matthias Tröltzsch, P W Kämmerer, Bilal Al-Nawas, Amely Hartmann","doi":"10.1186/s40729-026-00679-1","DOIUrl":"10.1186/s40729-026-00679-1","url":null,"abstract":"<p><strong>Purpose: </strong>To systematically review the efficacy and safety of resorbable scaffolds for bone augmentation of alveolar bone defects.</p><p><strong>Methods: </strong>A specific PICO question was formulated: In partially or fully edentulous patients requiring alveolar ridge augmentation (P), how do resorbable scaffolds (I), compared with non-resorbable devices (e.g., titanium meshes) or conventional bone augmentation techniques (C), perform in terms of clinical outcomes including bone gain, implant loss and success, and complication rates (O)? A PubMed/MEDLINE electronic search was conducted to identify clinical studies published until December 2025. No restrictions on publication date were imposed, and only studies published in the English language were considered. Selected studies were all studies on humans using resorbable devices for alveolar ridge augmentation; in vivo and in vitro studies were excluded. Study characteristics, operative techniques, materials, and clinical outcomes including complications, bone augmentation techniques, implant stability, survival and success rates were extracted and analyzed. Resorbable materials evaluated included polylactide (PLA), polycaprolactone (PCL), Polylactic Acid-Polyglycolic Acid (PLGA), and beta-tricalcium phosphate (β-TCP).</p><p><strong>Results: </strong>A total of 3704 articles were found, but only 7 studies met the pre-established inclusion criteria and were considered suitable for analysis. These studies included 39 patients and 45 edentulous ridges. Implant loss was only reported in one study. Complications occurred in three studies, with graft loss in 5 cases. Primary implant stability values averaged 35Ncm. Degradation time is an important determinant, but remains insufficiently studied/evaluated in the included evidence base.</p><p><strong>Conclusions: </strong>Resorbable scaffolds seem to represent viable alternatives to conventional bone grafting approache. Customized scaffolds may offer additional esthetic advantages. However, larger randomized controlled trials with longer follow-up periods and standardized outcome measures-including CBCT-based volumetric and linear bone gain, clearly defined complication categories, and implant-related outcomes such as stability, survival, and success-are required to enable robust evidence-based clinical recommendations.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"12 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13226745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical, radiographic, and histological evaluation of autogenous demineralized dentin matrix versus xenograft in alveolar ridge preservation: a randomized controlled trial.","authors":"Yin Xu, Hui Zhang","doi":"10.1186/s40729-026-00682-6","DOIUrl":"10.1186/s40729-026-00682-6","url":null,"abstract":"<p><strong>Purpose: </strong>This randomized controlled trial aimed to evaluate the clinical and histological efficacy of autogenous demineralized dentin matrix (DDM) compared with deproteinized bovine bone mineral (DBBM) for alveolar ridge preservation (ARP), with a specific focus on dimensional stability and remodeling dynamics over a 6-month follow-up period.</p><p><strong>Methods: </strong>Fifty patients requiring single-tooth extraction were randomized to receive ARP with either DDM (test group, n = 25) or DBBM (control group, n = 25). Dimensional changes were assessed by CBCT at baseline, 3 months, and 6 months. Histomorphometric analysis was performed on bone core biopsies harvested at 6 months.</p><p><strong>Results: </strong>Fifty patients were enrolled and randomly assigned to the test (DDM, n = 25) or control (DBBM, n = 25) group. At 3 months post-surgery, the test group exhibited significantly greater horizontal bone resorption at the mid-socket level (50%) compared with the control group (p = 0.006). However, at 6 months, no statistically significant differences were observed between the two groups regarding horizontal width reduction at any level (coronal, middle, apical) or vertical height reduction (p > 0.05). Histomorphometric analysis at 6 months revealed active new bone formation and good integration of graft particles in the DDM group, confirming its biodegradability and osteoconductive potential.</p><p><strong>Conclusions: </strong>Although autogenous DDM exhibited a faster remodeling rate and dimensional contraction in the early healing phase (3 months), it achieved long-term (6-month) dimensional stability comparable with that of the gold-standard xenograft. Furthermore, histological evidence of superior tissue integration suggests that DDM is a biologically viable and cost-effective alternative for alveolar ridge preservation.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13216369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148005320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of graft materials on bone regeneration using the osseous shell technique: an experimental study in rats.","authors":"Nyungkwang Kwon, Kazuhiro Imoto, Yuta Yanagisawa, Reina Minohara, Atsuya Abe, Shinnosuke Nogami, Shinsuke Ohba, Kensuke Yamauchi","doi":"10.1186/s40729-026-00693-3","DOIUrl":"10.1186/s40729-026-00693-3","url":null,"abstract":"<p><strong>Background: </strong>Autogenous bone (AB) is considered the gold standard for alveolar bone grafting, but its limitations have prompted the development of synthetic alternatives. The Shell technique provides a stable framework for bone augmentation. However, few studies have directly compared different graft materials under intraoral-like conditions, especially in mandibular models. This study aimed to quantitatively compare the osteogenic capacity of four graft materials-autogenous bone (AB), β-tricalcium phosphate (β-TCP), octacalcium phosphate collagen composite (OCPC), and atelocollagen absorbable sponge (AAS)-using a rat mandibular shell model that simulates intraoral conditions.</p><p><strong>Methods: </strong>Cortical bone blocks were harvested from the mandibular body of 36 male Wistar rats, and mandibular reconstruction was performed using the Shell technique with cortical bone plates. Four graft materials, particulate AB, β-tricalcium phosphate (β-TCP), octacalcium phosphate collagen composite (OCPC), and Atelocollagen Absorbable Sponge (AAS), were evaluated. Each postoperative cohort consisted of 12 rats in total (n = 3 per group × 4 groups), and histological and histomorphometric analyses were performed at 8, 12, and 16 weeks postoperatively.</p><p><strong>Results: </strong>AB generated significantly more new bone than the other materials at all time points. OCPC induced moderate limited regeneration until later stages, while β-TCP and AAS resulted in limited bone growth. The mandibular model effectively simulated oral anatomy and provided reliable structural support throughout the procedure.</p><p><strong>Conclusions: </strong>AB showed better osteogenic capacity than synthetic and composite materials. Use of the mandibular Shell technique with a rat model of mandibular defects proved useful for evaluating bone grafts under clinically relevant conditions.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13350785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomized controlled pilot trial comparing peri-implant tissue health beneath CAD/CAM-milled PEEK versus cobalt-chromium telescopic crowns for mandibular overdentures.","authors":"Iman A El Asfahani, Amr Khalifa, Doaa Tawfik, Emad Agamy, Mahmoud G Salloum","doi":"10.1186/s40729-026-00690-6","DOIUrl":"10.1186/s40729-026-00690-6","url":null,"abstract":"<p><strong>Purpose: </strong>This pilot randomized clinical trial compared peri-implant tissue health around milled cobalt-chromium (CoCr) versus polyether ether ketone (PEEK) secondary telescopic crowns in implant-retained mandibular overdentures over 12 months.</p><p><strong>Methods: </strong> Twelve completely edentulous patients received two implants each. After randomization, secondary crowns were fabricated from milled CoCr (n = 6 patients) or PEEK (n = 6 patients). Assessor-blinded outcome assessments such as marginal bone loss (MBL), probing depth (PD), and plaque index (PI) were performed at baseline, 6, 9, and 12 months post-loading. Statistical analysis used the patient as the unit of analysis.</p><p><strong>Results: </strong> No statistically significant inter-group differences were found at any time point. At 12 months, mean MBL was 0.48 ± 0.15 mm for CoCr and 0.45 ± 0.16 mm for PEEK (p = 0.735). PD increased over time within groups but remained comparable between groups (CoCr: 2.58 ± 0.58 mm, PEEK: 2.33 ± 0.41 mm at 12 months; p = 0.411). PI scores also showed no significant inter-group differences (p > 0.05).</p><p><strong>Conclusions: </strong> Over 12 months, milled PEEK and CoCr secondary telescopic crowns demonstrated comparable peri-implant tissue health. PEEK presents a viable metal-free alternative for this application. These preliminary findings warrant confirmation in larger, long-term studies.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"12 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147929043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volumetric analysis of bone resorption rate during lateral sinus lift: a retrospective study.","authors":"Thouveny Gabriel, Cuny Constance, Zitouni Anissa, Pujos Théo, Canceill Thibault, Cousty Sarah, Dubuc Antoine","doi":"10.1186/s40729-026-00691-5","DOIUrl":"10.1186/s40729-026-00691-5","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate 1-year bone resorption after lateral sinus lift and assess the influence of contributing factors (Schneiderian membrane perforation, sinus anatomy, and surgical variables).</p><p><strong>Methods: </strong>This observational retrospective monocentric study compared CBCT-based volumetric outcomes in patients undergoing lateral sinus lift between 2020 and 2025. Scans were obtained immediately postoperatively and at 1-year follow-up, allowing precise three-dimensional assessment of grafted bone volume and evaluation of the impact of intraoperative membrane perforation. Bone volumes were measured using 3D Slicer^® with semi-automatic segmentation, a 3D imaging method enabling precise volumetric assessment of grafted bone. Multivariate analyses were performed to explore associations between anatomical features, graft characteristics, and bone resorption.</p><p><strong>Results: </strong>Forty-one sinuses were analyzed (mean age 62.8 ± 11.4 years). Bone loss was classified as < 10% (n = 4), 10-25% (n = 12), 25-50% (n = 18), and ≥ 50% (n = 7). No significant differences in age, sex, initial bone height, volume, or membrane thickness were observed between perforation and control groups. Multivariate analysis suggested that initial graft volume and sinus morphology influenced cases with ≥ 50% resorption, while properly managed membrane perforations did not significantly affect graft stability.</p><p><strong>Conclusions: </strong>One-year bone resorption after lateral sinus lift is multifactorial, and proper management of Schneiderian membrane perforations minimizes their impact on graft volume. The management of perforations and surgical technique appear to play a more significant role in graft stability than the simple occurrence of a perforation.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13338078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147929002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technical and biological complications of implant-supported fixed complete dentures: a retrospective cohort study with up to 17 years of follow-up.","authors":"Djan Pelser, Markus Schepers, Samir Abou-Ayash, Monika Bjelopavlovic, Mark K Bremer, Leonie Grander, Stefan Wentaschek","doi":"10.1186/s40729-026-00689-z","DOIUrl":"10.1186/s40729-026-00689-z","url":null,"abstract":"<p><strong>Purpose: </strong>To retrospectively evaluate biological and technical complication rates of implant-supported fixed complete dentures (IFCDs) in edentulous jaws and to identify factors associated with complications over long-term follow-up.</p><p><strong>Methods: </strong>Between 2003 and 2023, 91 IFCDs supported by 498 implants were placed in 72 patients. Mean observation period was 6.8 years (0.5-17). Biological and technical complications were compared between materials. Time until first complication was estimated using Kaplan-Meier analysis and risk factors for recurrent complications were assessed through multivariable Andersen-Gill Cox regression.</p><p><strong>Results: </strong>Seven IFCDs failed, corresponding to a cumulative overall IFCD survival of 92.3%. Twenty-one of 498 implants (4.2%) were explanted. Overall prosthesis survival of resin veneered (RV) and ceramic veneered (CV) IFCDs did not differ (p = 0.85), whereas veneer fracture-free survival was significantly higher for CV IFCDs (p = 0.0094). In total, 169 complications were recorded, including recurrent events, whereas 49.5% of prostheses remained complication-free. Technical complications predominated, with veneer fractures representing the most frequent event. Biological complications such as peri-implantitis and implant loss occurred less frequently. Compared to base metal alloy-ceramic IFCDs, titanium-resin IFCDs exhibited a significantly higher overall complication risk (HR 4.25, p = 0.0015), particularly for veneer fractures (HR 7.11, p = 0.0029).</p><p><strong>Conclusions: </strong>Within the limitations of this long-term retrospective cohort study, IFCDs demonstrated high prosthesis and implant survival rates, but a considerable number of predominantly technical complications. The choice of framework and veneering material appears to influence long-term complication risk and should be carefully considered during treatment planning.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"12 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13172220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147928971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of internal irrigation versus external and combined irrigation during dental implant bed preparation, a systematic review.","authors":"Valerio Cimini, Alexandre Perez, Hamzah Shabana, Roberto Di Felice, Tommaso Lombardi","doi":"10.1186/s40729-026-00688-0","DOIUrl":"10.1186/s40729-026-00688-0","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to analyze the role and capacity of internal irrigation compared to external irrigation and, when applicable, combined irrigation to reduce and control bone heating during implant bed preparation.</p><p><strong>Methods: </strong>This systematic review was conducted according to predefined inclusion and exclusion criteria. A comprehensive literature search was performed in PubMed, Embase, Cochrane, Web of Science, and Google Scholar up to September 2025. Studies evaluating irrigation methods during implant osteotomy were included. Screening, selection, and risk of bias assessment were performed following a standardized protocol.</p><p><strong>Results: </strong>201 records were found. After deduplication, screening, and full-text evaluation, 10 in vitro studies were included for qualitative analysis and evaluation of risk of bias. At the same time, no animal studies fully met the inclusion criteria, and no randomized clinical trials were identified. Reports show that the peak temperature changes (ΔT) varied substantially, from 1.48 to 75.4 °C.</p><p><strong>Conclusion: </strong>In most studies, internal irrigation was shown to have superior cooling efficiency during the implant bed preparation compared to external irrigation, particularly in deeper osteotomies or when surgical guides were used. Combined irrigation also appeared to be a beneficial method. However, its performance varied depending on drill design and experimental setup. Risk of bias, assessed with the QUIN tool, was moderate to high, reflecting heterogeneity in study model, sampling, and reporting. Within the limitations of current evidence, internal irrigation emerges as an efficient method to control thermal and heat elevation during implant osteotomy.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13323638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary clinical evaluation of guided bone regeneration using carbonate apatite granules and poly(lactic acid/caprolactone) membranes: a prospective interventional study.","authors":"Akira Takahashi, Yoichiro Ogino, Tatsuya Matsuzaki, Masafumi Kihara, Satomi Wachi, Tomotaka Sugi, Yuma Hashiguchi, Kiyoshi Koyano, Yasunori Ayukawa","doi":"10.1186/s40729-026-00687-1","DOIUrl":"10.1186/s40729-026-00687-1","url":null,"abstract":"<p><strong>Purpose: </strong>This prospective clinical study aimed to evaluate the effectiveness and clinical applicability of guided bone regeneration (GBR) using a combination of carbonate apatite granules and poly(lactic acid/caprolactone) (PLCL) membranes in patients with alveolar bone deficiencies.</p><p><strong>Methods: </strong>A single-arm interventional study was conducted involving 16 participants and 18 grafted sites. GBR was performed using carbonate apatite granules mixed with saline and covered with PLCL membranes. Radiopaque markers were placed at the grafted sites to enable standardized radiographic evaluation. Pre- and post-operative computed tomography (CT) scans were analyzed to assess changes in crestal bone width and cross-sectional bone area. Postoperative complications were monitored at multiple time points, and statistical analyses were performed to evaluate bone augmentation outcomes.</p><p><strong>Results: </strong>Radiographic analysis revealed a statistically significant increase in crestal bone width and cross-sectional bone area following GBR (P < 0.01). Minor wound dehiscence was observed in 33.3% of cases at 2 weeks and 22.2% at 1 month, but no infections occurred at any time point. At 3 and 6 months, all sites showed uneventful healing. The combination of carbonate apatite and PLCL membranes demonstrated favorable biocompatibility and mechanical stability, contributing to predictable bone augmentation.</p><p><strong>Conclusions: </strong>GBR using carbonate apatite granules and PLCL membranes resulted in significant bone regeneration with low complication rates. This synthetic material combination may offer a reliable approach for GBR. Further studies with larger cohorts and longer follow-up are recommended to validate long-term outcomes and clinical relevance.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13323431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}