International Journal of Implant Dentistry最新文献

{"title":"Dental implant nanotopography for peri-implant tissue stability: soft-tissue sealing, innate immune calibration, and active biointerface regulation.","authors":"Takeru Kondo, Masahiro Yamada, Sara Ambo, Hiroshi Egusa","doi":"10.1186/s40729-026-00703-4","DOIUrl":"10.1186/s40729-026-00703-4","url":null,"abstract":"<p><strong>Purpose: </strong>Peri-implantitis is a major biological complication in implant dentistry, associated with bacterial biofilm formation and amplified by dysregulated host immune responses. Increasing evidence indicates that implant and abutment surface properties influence not only osseointegration but also microbial retention, soft-tissue sealing, and innate immune cell behavior. This narrative review aimed to summarize the current evidence on how dental implant nanotopography may affect peri-implantitis-related biological responses, with particular emphasis on innate immunity, region-specific peri-implant biointerfaces, and peri-implant tissue stability.</p><p><strong>Methods: </strong>Clinical, animal, and in vitro studies were reviewed to examine the pathogenesis of peri-implantitis, the roles of innate immune cells, the influence of implant and abutment surface topography on microbial and immune responses, and emerging nano-enabled strategies for the active regulation of peri-implant tissue responses.</p><p><strong>Results: </strong>Peri-implantitis progression is shaped by the interplay among the disruption of transmucosal soft-tissue sealing, microbial invasion, implant- or abutment-derived foreign-body stimuli, and sustained dysregulated innate immune activation. Nanotopographic surfaces regulate epithelial and fibroblastic attachment, extracellular matrix organization, neutrophil and macrophage responses, and osteocyte network formation via mechanotransduction. The biological effects of nanotopography are design-dependent and are influenced by nanoscale geometry, size, hydrophilicity, and associated physicochemical properties, including surface chemistry, wettability, and charge. Additionally, anisotropic nanospike surfaces and nano-enabled biomolecule delivery technologies illustrate the future possibility of active nanointerface regulation beyond conventional surface modification, although intracellular delivery technologies currently remain conceptual for dental implant applications.</p><p><strong>Conclusions: </strong>Implant and abutment nanotopography may contribute to peri-implant tissue stability by coordinating soft-tissue sealing, microbial retention control, innate immune calibration, and bone-interface resilience. Although direct clinical evidence remains limited, region-specific and functionally active nano-biointerfaces may offer new opportunities to reduce susceptibility to peri-implant inflammatory tissue breakdown.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13642854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-year marginal bone loss and survival rate of triangular-neck dental implants: a systematic review and meta-analysis.","authors":"Ziqi Xie, Sara Reda Sammour, Ryuji Shigemitsu, Nobuhiro Yoda, Toru Ogawa","doi":"10.1186/s40729-026-00702-5","DOIUrl":"10.1186/s40729-026-00702-5","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review aimed to evaluate the clinical performance of dental implants with a triangular neck, focusing on 1-year marginal bone loss (MBL) and implant survival rate.</p><p><strong>Methods: </strong>This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search of databases (PubMed, Scopus, and Web of Science) was completed on June 8, 2025. Randomized controlled trials (RCTs), retrospective and prospective studies, and case series that studied ≥ 10 implants, reporting on triangular-neck implants, were included. The Cochrane risk of bias 2 tool was used for RCTs, and the Joanna Briggs Institute case series checklist was used for nonrandomized studies. The results were summarized using a random-effects meta-analysis and sensitivity analysis was performed to assess robustness. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method was used to determine the certainty of evidence.</p><p><strong>Results: </strong>The search provided 115 titles after removal of duplicates. Eight studies met the inclusion criteria, five of which provided sufficient data for quantitative synthesis. The pooled analysis demonstrated a 1-year mean MBL of 0.35 mm (95% confidence interval [CI]: 0.24-0.46; heterogeneity; I² = 23.2%; p = 0.25) and an implant survival rate of 97.8% (95% CI: 95.4%-99.4%; I² = 0.0%; p = 0.96).</p><p><strong>Conclusions: </strong>Available single-arm evidence indicates that triangular-neck implants were associated with high implant survival rates and limited marginal bone level changes during the first year of follow-up. However, the current evidence does not permit conclusions regarding comparative clinical benefits relative to other implant designs.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13638964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148421067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of lithium disilicate and feldspathic CAD-on systems in implant-supported crowns: a combined mechanical testing and FEA study.","authors":"Elif Yeğin, Mustafa Hayati Atala","doi":"10.1186/s40729-026-00701-6","DOIUrl":"10.1186/s40729-026-00701-6","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to compare the failure loads and stress distribution of two different CAD-on systems used for implant-supported crowns.</p><p><strong>Methods: </strong>Implant-supported crowns were designed with CAD/CAM software (Cerec InLab V15.0) and fabricated using the CAD-on technique (n = 12 per group): Group ZF (zirconia core veneered with feldspathic ceramic) and Group ZL (zirconia core veneered with lithium disilicate ceramic). Following cementation onto titanium abutments, the restorations were subjected to failure load testing using a universal testing machine. Simultaneously, 3D models of FEA were generated to evaluate Von Mises, Maximum Principal, and Minimum Principal stress distributions across the restoration, implant, abutment, and supporting bone. The mean failure loads were compared using the independent samples t-test (p < 0.05).</p><p><strong>Results: </strong>Group ZL exhibited significantly higher failure loads (4649.22 ± 733.42 N) compared to Group ZF (2085.91 ± 555.61 N) (p < 0.001). While stress concentrations were primarily located at the implant neck in both groups, the distribution on the abutments differed significantly. In Group ZF, delamination was the primary failure mode (100%), whereas Group ZL presented bulk fractures and abutment deformation.</p><p><strong>Conclusion: </strong>While the Group ZL exhibited significantly superior failure load, the veneer delamination observed in Group ZF could act as a protective failure mode. Although the FEA revealed that different veneer ceramics did not alter the stress distribution across the implant and the bone, the selection of restorative system should ideally balance high fracture resistance with the biomechanical safety of the implant components.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the long-term prognosis (3-13 Years) of full mouth implant prosthetics combining zygomatic implants based on the all-on-four concept.","authors":"Takashi Uesugi, Yoshiaki Shimoo, Motohiro Munakata, Daisuke Sato, Kikue Yamaguchi, Minoru Sanda, Michiya Fujimaki, Kazuhisa Nakayama, Tae Watanabe, Paulo Malo","doi":"10.1186/s40729-026-00700-7","DOIUrl":"10.1186/s40729-026-00700-7","url":null,"abstract":"<p><strong>Purpose: </strong>Zygomatic implants (ZIs) are indicated for severely atrophic maxillae where conventional implant (CI) placement is difficult. Although ZIs show favourable outcomes, factors influencing their survival remain unclear. This retrospective study evaluated implant- and patient-related factors associated with ZI survival in full-arch immediate-loading rehabilitation using the all-on-four concept combining ZIs and CIs.</p><p><strong>Methods: </strong>A total of 923 implants (323 ZIs and 600 CIs) placed in 203 patients between 2010 and 2021 were analysed. Cumulative survival rates were estimated using the Kaplan-Meier method, and intergroup comparisons were performed using the log-rank test. Cox proportional hazards regression analyses were performed to calculate hazard ratios (HRs). Statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>Cumulative survival rates at 3-13 years were 94.5% and 95.9% at the patient and implant levels, respectively, for ZIs, and 97.9% and 98.7%, respectively, for CIs. ZIs showed significantly lower implant-level survival than CIs (p = 0.0178). Palatal positioning of the ZI platform was significantly associated with reduced implant-level survival (HR = 18.177, 95% CI: 1.418-233.053, p = 0.026). Systemic disease was significantly associated with reduced patient-level ZI survival after adjustment for sex and smoking status (HR = 14.872, 95% CI: 1.812-122.077, p = 0.012).</p><p><strong>Conclusions: </strong>Immediate full-arch rehabilitation combining ZIs and CIs achieved high long-term survival; however, palatal platform positioning and systemic disease were associated with ZI failure.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The masseter-buccinator periosteal flap prior to vertical bone augmentation in the mandibular region: case report and technical notes.","authors":"Elias Jean-Jacques Khoury, Tristan Hampe, Fouad Khoury","doi":"10.1186/s40729-026-00699-x","DOIUrl":"10.1186/s40729-026-00699-x","url":null,"abstract":"<p><strong>Background: </strong>Vertical bone augmentation in the posterior mandible presents significant challenges due to anatomical constraints and frequent deficiencies in soft tissue. Optimizing the soft-tissue phenotype prior to augmentation is critical to ensure stable wound closure and to provide the vascular support necessary for successful graft integration. This article introduces the pedicled masseter-buccinator periosteal flap, a novel technique that uses highly vascularized tissue to improve the quality and quantity of soft-tissue covering while also promoting graft survival.</p><p><strong>Case presentation: </strong>A patient presented with an edentulous site in the left mandibular molar region, exhibiting a severe combined vertical and horizontal ridge deficiency. Panoramic radiography revealed a non-restorable implant and a hopeless tooth in the premolar area, resulting in an extensive defect at this site. Following removal of the implant and tooth, a large three-dimensional ridge defect was confirmed intraoperatively. After local decontamination, a pedicled masseter-buccinator periosteal flap was dissected from the inner aspect of the cheek. A partial-thickness flap, which included limited buccinator and masseter muscle fibers along with the periosteal layer was elevated. The flap was rotated mesially and sutured to the lingual periosteum to achieve stable soft tissue augmentation. Finally, the overlying primary mucoperiosteal flap was sutured, resulting in a double-layered tissue closure. Two months later, three-dimensional ridge augmentation in the left mandibular premolar-molar region was performed using the split-bone block technique with autogenous graft harvested from the ipsilateral mandibular retromolar area. After three months, two implants were inserted in combination with a Kazanjian vestibuloplasty. After three months of healing, the implants were uncovered, allowing completion of the prosthetic rehabilitation. Radiographic follow-up at two years showed stable peri-implant bone levels and clinical examination confirmed healthy and stable soft-tissue conditions.</p><p><strong>Conclusion: </strong>The pedicled masseter-buccinator periosteal flap demonstrated to be a reliable and effective approach for soft tissue augmentation in the posterior mandible and support vertical bone grafting. Early clinical results indicate a high level of predictability with few complications making this technique a promising option in anatomically challenging cases.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148367952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trueness of implant placement, safety and surgeon experience with dynamic computer-assisted implant surgery : a prospective multi-centre cohort study.","authors":"Valentin Herber, Michael Gahlert, Achim von Bomhard, Florian Stelzle, Marcel Hanisch, Sebastian Kühl, Stefan Roehling","doi":"10.1186/s40729-026-00698-y","DOIUrl":"10.1186/s40729-026-00698-y","url":null,"abstract":"<p><strong>Purpose: </strong>This prospective multi-centre cohort study aims to evaluate the trueness and safety of implant placement using a Dynamic Navigation System (DNS) for implant bed preparation.</p><p><strong>Materials and methods: </strong>A total of 109 dental implants were inserted using a DNS for implant bed preparation in 76 patients by five experienced surgeons in four study centres. Before implantation, a preoperative CBCT scan was performed for each patient. This was subsequently aligned with an intraoral scan. After digital planning of the implant position, a holding tray for the intra-oral marker was designed and printed with a 3D printer. Procedure duration as well as adverse events were recorded. After implant bed preparation with DNS, the implants were placed in a freehand manner. Postoperative surface scans were superimposed onto the pre-operative planning data to evaluate the angular and spatial deviations. Descriptive statistics were followed by a one-sided, one-sample t-test to compare the data with performance goals extracted from literature-based benchmark data from freehand surgery.</p><p><strong>Results: </strong>The overall mean angular deviation was 3.37°±2.01° with a minimum of 0.20° and a maximum of 11.10°. The mean mesiodistal and orovestibular deviation at implant tip was 1.18 ± 0.66 mm. 3D deviation at implant base showed a mean ± SD of 1.24 ± 0.65 mm. No Serious Adverse Device Effects (SADE) were reported. The angular and mesiodistal, and orovestibular deviations were significantly better than the performance goals from freehand surgery (P<.001). The mean VAS was of 87.5 ± 14.3.</p><p><strong>Conclusions: </strong>The study-related DNS demonstrates trueness, safety and surgeon satisfaction.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13558529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148329098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro analysis of a glass solder matrix on ATZ-ceramic-samples using human dental pulp cells and L929 mouse fibroblasts.","authors":"Sandra Fuest, Moritz L Dyck, Mustafa Becerikli, Andreas Schmoock, Anders Henningsen, Christian Moss, Robert Mau, Hermann Seitz, Reinhard E Friedrich, Martin Gosau, Ralf Smeets, Levi Matthies","doi":"10.1186/s40729-026-00697-z","DOIUrl":"10.1186/s40729-026-00697-z","url":null,"abstract":"<p><strong>Purpose: </strong>Optimized surface properties are a pivotal factor for dental ceramic implants and overall implant success. After grit-blasting and spray-coating Aluminum Toughened Zirconia (ATZ) ceramic samples with a glass solder, the biological cell response was examined and compared to uncoated and solely grit-blasted samples of the same ceramic.</p><p><strong>Methods: </strong>In this study, a silica-based glass solder was evaluated for cytocompatibility, osteogenic differentiation, and hemocompatibility using L929 mouse fibroblasts and human dental pulp cells (HDPCs).</p><p><strong>Results: </strong>No toxic effects were observed for either coated or uncoated ATZ samples in direct or indirect tests, as assessed by live/dead staining. Differentiation and viability assays with HDPCs and L929 mouse fibroblasts showed no toxicity, and osteogenic differentiation was not impaired by the coating. Hemocompatibility testing with human whole blood revealed similar results for coated and uncoated ceramic specimens, with no hemolysis or adverse effects on standard hematological parameters.</p><p><strong>Conclusions: </strong>The glass solder coating was cytocompatible and hemocompatible under the tested in vitro conditions and did not impede osteogenic differentiation. These findings indicate that it can serve as a suitable substrate for the proliferation and spreading of L929 fibroblasts and HDPCs, with potential benefits for improving dental ceramic implant surfaces.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"12 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13294409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a preoperative accuracy prediction model using machine learning for implant placement in static-guided surgery: retrospective observational study.","authors":"Takuya Mino, Yurina Matsuoka, Ken'ichi Morooka, Kana Tokumoto, Hiroaki Shimizu, Yoko Kurosaki, Aya Kimura-Ono, Hiromitsu Kishimoto, Takuo Kuboki, Kenji Maekawa","doi":"10.1186/s40729-026-00696-0","DOIUrl":"10.1186/s40729-026-00696-0","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to develop a machine learning model capable of preoperatively predicting three-dimensional implant placement errors at the implant apex in static-guided surgery and to identify the clinical features associated with placement accuracy.</p><p><strong>Methods: </strong>Clinical data partially derived from a previous observational study were analyzed. In total, 181 patients and 480 implants placed using fully static-guided surgery were included in this study. The outcome variable was defined as three-dimensional implant placement error at the implant apex relative to the preoperative simulation, dichotomized as less than 0.5 mm or ≥ 0.5 mm. Twenty-one clinical and radiographic factors previously suggested to influence the placement accuracy were used as explanatory variables. The feature importance was evaluated using three gradient boosting decision tree models. Furthermore, a stacking model combining multiple classifiers was constructed, and the classification performance was assessed using ten-fold cross-validation.</p><p><strong>Results: </strong>The feature importance analysis identified 12 features associated with implant placement errors. The stacking model demonstrated superior classification performance compared to individual classifiers. The true positive rate was 0.73, false negative rate was 0.27, false positive rate was 0.14, and true negative rate was 0.86.</p><p><strong>Conclusions: </strong>The proposed stacking model correctly classified 86% of cases with implant placement error less than 0.5 mm and 73% of cases with implant placement error of ≥ 0.5 mm. These findings suggest that the proposed model may support the preoperative evaluation of implant placement accuracy in static-guided surgeries.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13538333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148294669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The surface-agnostic advantage for peri-implant health: UV photofunctionalization as a positive-sum strategy for biofilm suppression and soft-tissue barrier-a systematic review with qualitative synthesis.","authors":"Keiji Komatsu, Jasper Kim, Nicholas Her, Ryan Alpers, Natsumi Saito, Rune Shibata, Irina Fedorowicz, Sei Jin Kim, Naryung Kim, Tammy Lu, Andrew Tran, Jisub Lim, Wakako Sakaguchi, Takuma Sato, Shugo Haga, Takanori Matsuura, Wonhee Park, Takahiro Ogawa","doi":"10.1186/s40729-026-00695-1","DOIUrl":"10.1186/s40729-026-00695-1","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;Long-term dental implant success depends on a biologic \"race to the surface,\" in which osteogenic cells, peri-implant soft-tissue cells, and bacterial pathogens compete for early dominance at the implant-tissue interface. Because implant surface design is often optimized for one objective at the expense of another (e.g., micro-roughness to accelerate osteoconductivity but with increased plaque-retention risk; relatively smooth transmucosal surfaces to discourage bacterial attachment despite uncertainty regarding optimal soft-tissue integration), strategies that enhance peri-implant health without forcing topographical trade-offs are needed. Ultraviolet (UV) photofunctionalization-by removing storage-acquired hydrocarbons (\"biological aging\") and converting surfaces to a high-energy, superhydrophilic state-has been proposed as a chairside, topography-preserving approach to improve interfacial biology. This systematic review evaluates whether UV photofunctionalization of titanium and zirconia surfaces provides clinically relevant advantages for (1) reduction of bacterial attachment and biofilm formation, (2) peri-implant soft-tissue responses relevant to mucosal sealing, and (3) human clinical outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;After systematic literature search, screening and full-text evaluation, a total of 34 articles, including 9 bacterial/biofilm, 13 soft-tissue (1 overlapping between bacterial and soft-tissue), and 13 clinical studies were selected. Findings were synthesized qualitatively with attention to protocol heterogeneity (UV wavelength band, exposure duration, device configuration, and material and surface types).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Across experimental models, UV photofunctionalization most consistently reduced early bacterial attachment and/or early biofilm accumulation across several titanium surface topographies, supporting an early anti-adhesive and biofilm-suppressive phenotype. Soft-tissue studies generally demonstrated enhanced fibroblast/epithelial attachment, spreading, and functional behaviors relevant to sealing on both titanium and zirconia, although the optimal underlying topography for soft-tissue integration remains unresolved. Clinically, the most consistent signal was accelerated and enhanced implant stability development, while selected studies also suggested favorable trends in peri-implant soft-tissue parameters and/or crestal bone maintenance. However, clinical outcomes remained variable and were limited by heterogeneity in UV protocols, surface systems, endpoints, and follow-up duration.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;UV photofunctionalization can be conceptualized as a surface-agnostic physicochemical reactivation technology: a topography-preserving enhancement that restores high surface energy and favorable surface chemistry without altering the underlying surface architecture. Current evidence for this concept is strongest for titanium, whereas supportive e","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13291283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148271243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement accuracy of dental cone-beam computed tomography for assessing submillimeter distances between implant and mandibular canal: a phantom study.","authors":"Hozumi Yoshihara, Eiichi Honda, Yoshizo Matsuka","doi":"10.1186/s40729-026-00694-2","DOIUrl":"10.1186/s40729-026-00694-2","url":null,"abstract":"<p><strong>Purpose: </strong>Accurate assessment of the distance between dental implants and the mandibular canal is essential for preventing nerve injury. Although cone-beam computed tomography (CBCT) is widely used for implant planning, its accuracy in resolving submillimeter distances remains uncertain. This study evaluated the measurement accuracy of CBCT for assessing distances below 1.0 mm.</p><p><strong>Methods: </strong>A custom phantom enabling 0.0-1.0 mm implant-canal distances in 0.1-mm increments was developed. CBCT images were acquired at varying distances, positional shifts (X, Y, Z), and tube voltages. Five dentists involved in implant treatment measured the implant-canal distances using medical-grade and general-purpose monitors. Measurement error and contributing imaging factors were statistically analyzed.</p><p><strong>Results: </strong>CBCT did not reliably distinguish distances ≤ 0.4 mm, with the greatest instability observed at 0.3 mm (interquartile range = 0.121). Although a linear trend was observed from 0.1 to 0.4 mm, variability exceeded clinically acceptable limits. For distances ≥ 0.5 mm, reproducibility was high, but CBCT consistently underestimated the true gap by 0.2-0.3 mm. The central field of view produced the most stable measurements, whereas accuracy decreased with off-center positioning. Tube voltage and monitor type had minimal influence on measurement accuracy.</p><p><strong>Conclusions: </strong>CBCT cannot accurately identify implant-canal distances ≤ 0.4 mm, which may directly affect clinical risk assessment. Even for distances ≥ 0.5 mm, CBCT underestimates the true distance by 0.2-0.3 mm. These findings provide practical guidance for setting safe margins in implant planning and postoperative evaluation.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13385543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148194560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}