Jaana-Sophia Kern, Esra Salin, Gregor Slavicek, Florian Slavicek, Dirk Elvers, Frank Hölzle, Stefan Wolfart
{"title":"A clinical pilot study on overdentures retained by two unsplinted narrow-diameter implants- oral health-related quality of life and masticatory function.","authors":"Jaana-Sophia Kern, Esra Salin, Gregor Slavicek, Florian Slavicek, Dirk Elvers, Frank Hölzle, Stefan Wolfart","doi":"10.1186/s40729-025-00637-3","DOIUrl":"https://doi.org/10.1186/s40729-025-00637-3","url":null,"abstract":"<p><strong>Purpose: </strong>This prospective clinical pilot study aimed to evaluate oral health-related quality of life (OHRQoL) and both objective and subjective masticatory function following treatment with implant-supported overdentures on two reduced-diameter titanium-zirconium implants in the edentulous maxilla and mandible.</p><p><strong>Methods: </strong>Ten edentulous patients received two implants each in the maxillary and mandibular canine regions. Implant-supported overdentures were placed after a conventional healing period. Patients completed a shortened form of the Oral Health Impact Profile (OHIP-G14) and rated their chewing ability on a visual analog scale (VAS) at baseline and after 6, 12, 24, and 36 months. A standardized masticatory function test assessed objective chewing function. Statistical analysis comprised descriptive analysis and changes or differences in means were analyzed using different tests (Wilcoxon signed rank test, Friedman test).</p><p><strong>Results: </strong>Significant increases in subjective ability to eat various foods were noted after six months (P ≤.05). The mean total OHIP score decreased significantly from 33.2 at baseline to 4.7 at the 36-month follow-up. Objective masticatory efficacy showed significant improvement immediately after treatment (P =.005), with effects consistent over 36 months. At that time, six maxillary implants had been lost, while no mandibular implants had failed.</p><p><strong>Conclusions: </strong>In this clinical pilot study, the rehabilitation of a completely edentulous maxilla and mandible with two implants and a removable overdenture significantly enhanced OHRQoL and both subjective and objective masticatory ability over an observation period of 36 months.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"48"},"PeriodicalIF":3.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chutikarn Somngam, Sutiwat Samartkit, Sukrit Kanchanasurakit, Frank Peter Strietzel, Pathawee Khongkhunthian
{"title":"New bone formation of biphasic calcium phosphate bone substitute material: a systematic review and network meta-analysis of randomized controlled trials (RCTs).","authors":"Chutikarn Somngam, Sutiwat Samartkit, Sukrit Kanchanasurakit, Frank Peter Strietzel, Pathawee Khongkhunthian","doi":"10.1186/s40729-025-00636-4","DOIUrl":"10.1186/s40729-025-00636-4","url":null,"abstract":"<p><strong>Objective: </strong>• To systematically determine the effectiveness of biphasic calcium phosphate (BCP) as bone substitute materials (BSM) compared to other BSMs for new bone formation in dental implant treatment through a network meta-analysis (NMA).</p><p><strong>Materials and method: </strong>• Following PRISMA-NMA guidelines, randomized controlled trials (RCTs) on lateral sinus augmentation and dental implants comparing BCP with other BSMs for histomorphometric new bone formation were included. Studies were retrieved from MEDLINE, Cochrane, Scopus, and Embase (up to November 2024), with quality assessed via the Cochrane risk of bias 2 (RoB2.0) tool. Analysis included direct and network meta-analyses using a random-effects model, with SUCRA scores determining treatment rankings. The PROSPERO registration number was CRD42024607526.</p><p><strong>Results: </strong>• Of 268 studies, 11 met criteria, covering 283 patients and 362 sinus augmentations using autografts (AB), allografts (AL), beta tricalcium phosphate (TCP), BCP, and xenografts (Xeno). NMA showed AB resulted in 12.33% more new bone formation than BCP (95% CI: 10.74, 13.93), with AL showing 5.14% more (95% CI: 3.33, 6.95). Xeno showed 4.14% less bone formation than BCP (95% CI: -6.38, -1.90). AB ranked highest for new bone formation, followed by AL, BCP, TCP, and Xeno. Residual graft material was highest in Xeno (6.21%; 95% CI: 2.81, 9.61).</p><p><strong>Conclusion: </strong>• BCP demonstrated sufficient new bone formation, outperforming xenografts in both bone formation and residual graft material. While autografts and allografts exhibited superior bone regeneration, BCP remains an effective option for bone augmentation treatments.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"47"},"PeriodicalIF":3.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of digital and conventional methods for verifying the fitness of CAD/CAM crowns on abutments with different shapes.","authors":"Michi Abe, Kazuhiro Kon, Shota Fukazawa, Hisatomo Kondo","doi":"10.1186/s40729-025-00632-8","DOIUrl":"10.1186/s40729-025-00632-8","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the marginal and internal compatibility of computer-aided design and computer-aided manufacturing crowns produced via a digital workflow using an intraoral scanner, and to compare this digital-detection technique with the conventional fit test using silicone rubber (silicone-compatibility technique) on various abutments.</p><p><strong>Methods: </strong>Implant bodies were placed in the maxillary right central incisor and mandibular right first molar of reference models. Digital scans were acquired using an intraoral scanner, and abutments were prepared. Twenty-four crowns with a cement space of 70 μm were fabricated from the digital file of the abutment. The crown's inner surface, abutment, and occlusal surface were scanned. The gaps between the crown and abutment were measured using stereoscopic image analysis software based on standard triangulated language data, and the accuracy of the fit was verified using silicone rubber.</p><p><strong>Results: </strong>Significant differences (P < 0.05) were observed between the silicone-compatibility and digital-detection techniques for the maxillary central incisor at the incisal edge and the palatal lower region, and for the mandibular first molar at the occlusal surface and the center of lingual axis. The digital-detection technique yielded values closer to 70 μm for the cement space. The values measured using the silicone-compatibility technique exhibited greater variation than those measured using the digital-detection technique.</p><p><strong>Conclusions: </strong>The novel digital-detection technique had superior or equivalent performance compared to the silicone-compatibility technique and could be beneficial for verifying crown fitness accuracy.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"46"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12214169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kun Wang, Jiatong Zhang, Mengyao Ding, Yifan Xie, Yan Wang, Chuyi Jin, Mengqing Yan, Lipei Liu, Cheng Ding, Xing Chen
{"title":"Comparative evaluation of porcine and bovine bone xenografts in bone grafting: a systematic review and meta-analysis.","authors":"Kun Wang, Jiatong Zhang, Mengyao Ding, Yifan Xie, Yan Wang, Chuyi Jin, Mengqing Yan, Lipei Liu, Cheng Ding, Xing Chen","doi":"10.1186/s40729-025-00630-w","DOIUrl":"10.1186/s40729-025-00630-w","url":null,"abstract":"","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"45"},"PeriodicalIF":3.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Muchnik, Gavriel Chaushu, Eli Rosenfeld, Shaked Adut, Aiman Elmograbi, Meir Debecco, Amir Laviv, Daya Masri
{"title":"Implant displacement to the maxillary sinus- a retrospective multicenter cohort study and a management protocol.","authors":"Daniel Muchnik, Gavriel Chaushu, Eli Rosenfeld, Shaked Adut, Aiman Elmograbi, Meir Debecco, Amir Laviv, Daya Masri","doi":"10.1186/s40729-025-00629-3","DOIUrl":"10.1186/s40729-025-00629-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the potential complication of implant displacement into the maxillary sinus, exploring its etiology and various management strategies, while proposing a systematic approach for clinicians to effectively address this evolving complication.</p><p><strong>Materials and methods: </strong>This retrospective multi-center cohort study evaluated patients with dental implant migration into the maxillary sinus treated between 2010 and 2023 at two Israeli medical centers. Data included demographics, symptoms, clinical findings, and treatment modalities.</p><p><strong>Results: </strong>32 patients (mean age: 62.3 years) were analyzed, with a notable incidence of sinusitis and oroantral fistulas. 91% required surgical intervention, predominantly Functional Endoscopic Sinus Surgery (63%). The majority of displacements occurred during the implantation process, often correlating with clinical symptoms.</p><p><strong>Conclusion: </strong>As shown in our study, displacement of implants into maxillary sinus, often leads to sinusitis and oroantral fistula. A proposed treatment algorithm emphasizes surgical intervention, particularly Functional Endoscopic Sinus Surgery, based on symptoms and clinical signs.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"44"},"PeriodicalIF":3.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebahat Kaya, Bhárbara Marinho Barcellos, Shengchi Fan, Adriano Azaripour, Christian Walter, Amely Hartmann, Keyvan Sagheb
{"title":"Risk factors for dehiscence in alveolar ridge augmentation using patient-specific titanium mesh: a retrospective analysis.","authors":"Sebahat Kaya, Bhárbara Marinho Barcellos, Shengchi Fan, Adriano Azaripour, Christian Walter, Amely Hartmann, Keyvan Sagheb","doi":"10.1186/s40729-025-00623-9","DOIUrl":"10.1186/s40729-025-00623-9","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective study aimed to evaluate the incidence of dehiscence following bone augmentation with patient-specific titanium meshes and to identify factors associated with its occurrence.</p><p><strong>Material and methods: </strong>Patients who underwent bone grafting with patient-specific titanium mesh between December 2014 and October 2021 were included. The primary outcome was the occurrence of dehiscence. The occurrence of dehiscences was recorded during the following time phases, enabling the determination of whether dehiscences occur early (< 2 weeks), in the mid-term (2-9 weeks), or later in the healing phase (> 9 weeks).</p><p><strong>Results: </strong>A total of 78 patients undergoing 85 titanium mesh augmentations were included, with a mean follow-up period of 1.2 years. Dehiscence occurred in 33 meshes (38.8%), with 51.5% of these events arising during the early healing phase. In no case was premature removal of the titanium mesh required due to dehiscence. A statistically significant association was observed between dehiscence and both smoking behavior (p < 0.001) and the anatomical location of the maxillary defect (p = 0.029). No significant associations were found between dehiscence and gender (p = 0.160), periodontitis (p = 0.512), gingival phenotype (p = 0.495), defect type (p = 0.490), augmented bone volume (p = 0.373), or incision type (p = 0.354). Logistic regression analysis further identified smoking (odds ratio: 7.07; 95% CI: 2.19-22.80) and maxillary defect alveolar (odds ratio: 11.86; 95% CI: 0.34-4.60) as significant predictors of dehiscence.</p><p><strong>Conclusion: </strong>Dehiscence following customized titanium mesh augmentation was significantly associated with smoking and the location of the maxillary defect, underscoring the importance of early detection and timely intervention.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"42"},"PeriodicalIF":3.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
So-Ra Lee, Jooseong Kim, Woong Kim, Seok-Jun Kim, Yong-Gun Kim, Won-Pyo Lee
{"title":"Volumetric stability of moldable octacalcium phosphate in guided bone regeneration: a CBCT-based ex vivo study.","authors":"So-Ra Lee, Jooseong Kim, Woong Kim, Seok-Jun Kim, Yong-Gun Kim, Won-Pyo Lee","doi":"10.1186/s40729-025-00631-9","DOIUrl":"10.1186/s40729-025-00631-9","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to evaluate the effect of flap suturing on the movement of graft materials during Guided Bone Regeneration (GBR) and to analyze the stability of moldable octacalcium phosphate (mOCP) depending on the type of graft material and membrane fixation method using Cone Beam Computed Tomography (CBCT).</p><p><strong>Methods: </strong>A total of 60 standardized rectangular-shaped bone defects were created in the alveolar ridges of mandibles from 5-6-month-old pigs (20 defects per group), and implants (4.0 mm in diameter, 10.0 mm in height) were placed into each defect. The control group employed particle-type OCP and a collagen membrane, experimental group 1 utilized particle-type OCP and a collagen membrane with fixation pins, and experimental group 2 employed mOCP and a collagen membrane. CBCT analysis was performed to evaluate changes in horizontal thickness (HT) at the grafted sites.</p><p><strong>Results: </strong>CBCT analysis revealed that the percentage reduction in HT at the implant shoulder level was significantly lower in experimental group 1 (16.7%) and experimental group 2 (16.3%) compared to the control group (31.5%), with no statistically significant difference observed between experimental groups 1 and 2.</p><p><strong>Conclusion: </strong>The use of mOCP in guided bone regeneration demonstrated comparable volumetric stability to grafts utilizing collagen membranes fixed with titanium pins, suggesting its potential to simplify surgical procedures by eliminating the need for additional fixation devices.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"43"},"PeriodicalIF":3.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jung Min Cho, Namki Hong, Yumie Rhee, Wonse Park, Kyung Chul Oh, Yanggyung Seo, Hwangyu Lee, Hyeon-Gyu Jo, Yunji Shin, Jun-Young Kim
{"title":"Clinical outcomes and bone marker changes in postmenopausal women with dental implants: a one-year prospective study.","authors":"Jung Min Cho, Namki Hong, Yumie Rhee, Wonse Park, Kyung Chul Oh, Yanggyung Seo, Hwangyu Lee, Hyeon-Gyu Jo, Yunji Shin, Jun-Young Kim","doi":"10.1186/s40729-025-00628-4","DOIUrl":"10.1186/s40729-025-00628-4","url":null,"abstract":"<p><strong>Objectives: </strong>The feasibility of dental implants in patients with osteoporosis remains controversial, with limited prospective studies on quantitative changes in bone mineral density (BMD) and bone turnover markers (BTMs). This study assessed implant survival and clinical outcomes while evaluating systemic changes during 1 year of implant treatment.</p><p><strong>Materials and methods: </strong>Postmenopausal women requiring dental implants were enrolled at the Yonsei University Dental Hospital. BMD and BTMs were evaluated in collaboration with the endocrinology department. Participants were divided into two groups: Group A (T-score ≥ -2) and Group B (T-score < -2). All implants used in the study were surface-treated with hydroxyethyl piperazine ethane sulfonic acid (HEPES), and clinical, radiographic, and systemic parameters were monitored for over 1 year.</p><p><strong>Results: </strong>Between April 2022 and May 2024, 45 implants were placed in 36 patients (mean age: 68 years). Group A included 17 patients with 21 implants (mean age: 66 years), and Group B included 19 patients with 24 implants (mean age: 70 years). The cumulative survival rate was 100%. Resonance frequency analysis at 12 months revealed a mean implant stability tester value of 71.4 ± 5.52, indicating excellent osseointegration. Peri-implant bone loss averaged 0.54 ± 0.35 mm. No implant failures occurred, with stable plaque scores, probing depths, and bleeding upon probing. BMD and BTMs changes were minimal.</p><p><strong>Conclusions: </strong>Both groups achieved high implant survival and stable clinical outcomes. Systemic evaluations confirmed only minor changes in BMD and BTMs over 1 year. Larger multicenter studies are required to confirm the systemic safety of dental implants in patients with osteoporosis.</p><p><strong>Clinical relevance: </strong>Dental implants show excellent survival and stability in postmenopausal women with osteoporosis, with minimal impact on bone density and turnover-supporting their safe use in this population.</p><p><strong>Clinical trial registration: </strong>This study was prospectively registered at the Clinical Research Information Service of the National Research Institute of Health, Republic of Korea (KCT0007100). The registration details can be accessed at https://cris.nih.go.kr .</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"41"},"PeriodicalIF":3.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philipp Becker, Andreas Pabst, Diana Heimes, Nadine Wiesmann-Imilowski, Sven Schumann, Peer W Kämmerer
{"title":"Biomechanical and cellular assessment of novel partially demineralized allogeneic bone plates: an ex-vivo and in-vitro study.","authors":"Philipp Becker, Andreas Pabst, Diana Heimes, Nadine Wiesmann-Imilowski, Sven Schumann, Peer W Kämmerer","doi":"10.1186/s40729-025-00625-7","DOIUrl":"10.1186/s40729-025-00625-7","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare commercial allogeneic cortical bone plates (cCP) with innovative, differently demineralized CP (dCP) in biomechanics and human osteoblast (HOB) viability ex-vivo and in-vitro.</p><p><strong>Methods: </strong>Breaking strength (BS; in N) and flexibility (F; in mm) of cCP and dCP were assessed and compared using four groups ((1) non-hydrated, (2) hydrated for 10, (3) 30, and (4) 60 min in saline), respectively. Cell viability of HOB was evaluated by resazurin reduction on non-hydrated cCP and dCP after 3, 7, and 10 days. Scanning electron microscopy (SEM) visualized CP breaking edges, internal structures, HOB cell morphology, and growth patterns.</p><p><strong>Results: </strong>BS of hydrated dCP (d10: 15.45 ± 7.01 N, d30: 19.40 ± 3.78 N, d60: 20.31 ± 4.90 N) was significantly lower than that of non-hydrated dCP (d0: 74.70 ± 29.48 N) and native and hydrated cCP (c0: 75.00 ± 19.27 N, c10: 83.73 ± 10.92 N, c30: 83.80 ± 22.63 N, c60: 75.58 ± 14.25 N, p < 0.001 each). Next, dCP groups (d0: 2.64 ± 0.78 mm, d10: 2.14 ± 1.15 mm, d30: 2.76 ± 3.78 mm, d60: 2.86 ± 0.89 mm) exhibited significantly higher F than cCP groups (c0: 0.49 ± 0.14 mm, c10: 0.66 ± 0.10 mm, c30: 0.67 ± 0.16 mm, c60: 0.59 ± 0.12 mm, p < 0.05 each). No significant differences in F were observed among the different dCP groups. HOB cell viability was significantly increased on cCP compared to dCP after 7 (97.64 ± 2.11% vs. 76.88 ± 4.82%) and 10 days (96.14 ± 4.13% vs. 76.45 ± 4.64%; p < 0.001 each). SEM revealed well-defined breaking edges in cCP, whereas dCP displayed tear-off edges with shearing extensions. SEM showed disordered growth patterns and a physiological HOB cell morphology on dCP, contrasting with a parallel growth of fibroblast-like-looking HOB on cCP.</p><p><strong>Conclusions: </strong>Compared to cCP, dCP showed increased flexibility but lower breaking strength and reduced HOB vitality. The increased flexibility and a decrease in breaking strength are likely due to differences in elasticity between dCP and cCP. The use of dCP may improve clinical handling efficiency.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"40"},"PeriodicalIF":3.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12092848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kirollos H Botros, Doaa Adel-Khattab, Abdelrahman K Eldabe, Hala A Abuel Ela
{"title":"Early versus conventional loading for fully guided immediate implant placement in molar sites: a randomized controlled clinical study.","authors":"Kirollos H Botros, Doaa Adel-Khattab, Abdelrahman K Eldabe, Hala A Abuel Ela","doi":"10.1186/s40729-025-00624-8","DOIUrl":"10.1186/s40729-025-00624-8","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate early versus conventional loading in immediate implants for molars. This study aims to answer the following PICO (Patient, Intervention, Comparison, and Outcome) question: In patients over 18 years of age, does early loading of immediately placed implants in molar areas result in a similar implant survival rate and marginal bone loss as conventional loading?</p><p><strong>Methods: </strong>Twenty-seven patients (15 women and 12 men) received a total of 30 implants immediately after molar extraction. The surgical treatment protocol entailed atraumatic tooth extraction without flap elevation. Non-invasive quantitative analyses were used to assess implant stability. After an uneventful healing period, the 30 implants were restored with screw-retained monolithic zirconia prosthesis, half of which after 6 weeks (G1) and the other half after 3 months (G2).</p><p><strong>Results: </strong>Regarding the survival rate, the Kaplan-Meier and log-rank test showed that there was no statistically significant difference between both groups (p = 1). Implant stability quotient at the prosthetic phase of both groups (6 weeks in G1 and 3 months in G2) revealed no statistically significant difference (G1 RFA74.4 (SD 5.54) - DCA 79.07 (SD 5.75))/G2 RFA 73.67 (SD 5.7), - DCA78.93 (SD 4.48).</p><p><strong>Conclusions: </strong>Early loading of immediately placed implants in molar sites is considered a predictable treatment modality provided that ideal implant position and adequate insertion torque are achieved.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"11 1","pages":"39"},"PeriodicalIF":3.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12092919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}