Alexander Swalsky, Sammy S Noumbissi, Thomas G Wiedemann
{"title":"The systemic and local interactions related to titanium implant corrosion and hypersensitivity reactions: a narrative review of the literature.","authors":"Alexander Swalsky, Sammy S Noumbissi, Thomas G Wiedemann","doi":"10.1186/s40729-024-00578-3","DOIUrl":"10.1186/s40729-024-00578-3","url":null,"abstract":"<p><p>Both commercially pure titanium and titanium alloys are established biomaterials for implantation in bone and are widely used today in dentistry. Titanium particulates have been shown in some patient clusters to induce cellular immune mediators responsible for type I and IV hypersensitivity reactions, causing amplified corrosion, osteolysis, and increased odds of implant failure. Systemically, titanium particles were found to affect varying organ tissues and cause potentially harmful effects. In vivo and vitro studies have shown that titanium dental implant corrosion can be induced by factors relating to bio-tribocorrosion. In this literature review, the consequences of titanium implant corrosion and particulate dissemination are discussed and later juxtaposed against a promising novel implant material, zirconia. Zirconia offers characteristics similar to titanium along with additional advantages such as being non-corrosive and having a lower propensity for inducing immune responses. From the mounting evidence discussed in this article, metal allergy testing would be advantageous for choosing an appropriate implant material to minimize potential adverse effects on cellular functions of local and diffuse tissues. Objective: This literature review aims to elucidate and describe mechanisms in which titanium implants may become corroded and induce cellular aberrations both locally and systemically in vivo. Implications of this study provide supportive evidence regarding the selection of appropriate biomaterials for implant patients susceptible to mounting a hypersensitivity reaction to titanium.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"58"},"PeriodicalIF":3.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implant-supported fixed prostheses with cantilever: a systematic review and meta-analysis.","authors":"Yusuke Kondo, Kiyoshi Sakai, Hajime Minakuchi, Takuya Horimai, Takuo Kuboki","doi":"10.1186/s40729-024-00573-8","DOIUrl":"10.1186/s40729-024-00573-8","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review (SR) aimed to investigate whether the presence of a cantilever affects the results of implant treatment for partial edentulism, including an analysis of the anterior and posterior regions of the dental arches.</p><p><strong>Methods: </strong>An electronic search was performed, and original articles published between 1995 and November 2023 were included. The outcomes were the implant survival rate, patient satisfaction, occurrence of mechanical complications, and marginal bone loss around the implants. Two SR members independently examined the validity of the studies, extracted evidence from the included studies, and performed risk of bias assessment, comprehensive evidence evaluation, and meta-analysis.</p><p><strong>Results: </strong>Nine studies met our inclusion criteria. Implant survival rate tended to be lower in the cantilever group, and marginal bone loss tended to be higher in the cantilever group; however, there was no significant difference. There was no significant difference in patient satisfaction based on the presence or absence of a cantilever. Moreover, the incidence of mechanical complications was significantly higher in the cantilever group. According to the analysis of anterior and posterior regions, implant survival rate tended to be lower in the cantilever group of the posterior region, and marginal bone loss around the implants tended to be higher in the cantilever group of the anterior region.</p><p><strong>Conclusion: </strong>Implant-supported fixed prostheses with cantilevers did not negatively affect implant survival rate, marginal bone loss, or patient satisfaction. However, the incidence of mechanical complications significantly increased in the cantilever group.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"57"},"PeriodicalIF":3.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunil Kumar Vaddamanu, Ravinder S Saini, Rajesh Vyas, Masroor Ahmed Kanji, Abdulkhaliq Ali F Alshadidi, Salah Hafedh, Marco Cicciù, Giuseppe Minervini
{"title":"A comparative study on bone density before and after implant placement using osseodensification technique: a clinical evaluation.","authors":"Sunil Kumar Vaddamanu, Ravinder S Saini, Rajesh Vyas, Masroor Ahmed Kanji, Abdulkhaliq Ali F Alshadidi, Salah Hafedh, Marco Cicciù, Giuseppe Minervini","doi":"10.1186/s40729-024-00565-8","DOIUrl":"10.1186/s40729-024-00565-8","url":null,"abstract":"<p><strong>Background: </strong>Dental implant success critically depends on the primary stability of the implant, which is significantly influenced by the bone density at the osteotomy site. Traditional drilling techniques for osteotomy preparation often compromise bone volume and quality. This study aimed to evaluate the impact of osseodensification, a novel osteotomy preparation technique, on bone density and implant stability. The technique utilizes specialized drills that operate in a counter-clockwise direction to compact autografted bone laterally and apically, preserving and enhancing bone density.</p><p><strong>Methods: </strong>A total of 32 patients undergoing dental implant surgery were included in this study. Pre-operative and post-operative bone densities at the apical, mesial, and distal regions of the osteotomy sites were measured using Dentascan (CT) and analyzed with Radiant DICOM software. The study utilized osseodensification drills for osteotomy preparation, comparing pre-operative and post-operative bone densities to assess the technique's efficacy.</p><p><strong>Results: </strong>The study found a statistically significant increase in bone density post-operatively (p < 0.001), with the greatest improvement observed in the distal region, followed by the mesial and apical regions. The findings underscore osseodensification's effectiveness in enhancing bone density and primary stability, with the distal region exhibiting the highest bone density.</p><p><strong>Conclusion: </strong>Osseodensification represents a significant advancement in implant dentistry for osteotomy preparation. By preserving and increasing bone density through compact autografting, this technique not only improves primary stability but also offers potential benefits in indirect sinus lifting and alveolar ridge expansion. The study advocates for the broader adoption of osseodensification drills in clinical practice to achieve better outcomes in dental implantology.</p><p><strong>Trial registration: </strong>This study received ethical approval from The Research Ethics Committee at King Khalid University's under Approval no. ECM#2024 - 216. Additionally, it was registered with ClinicalTrials.gov, identifier no: NCT06268639.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"56"},"PeriodicalIF":3.1,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11576667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siddharth Shanbhag, Javier Sanz-Esporrin, Carina Kampleitner, Stein-Atle Lie, Reinhard Gruber, Kamal Mustafa, Mariano Sanz
{"title":"Peri-implant bone regeneration in pigs.","authors":"Siddharth Shanbhag, Javier Sanz-Esporrin, Carina Kampleitner, Stein-Atle Lie, Reinhard Gruber, Kamal Mustafa, Mariano Sanz","doi":"10.1186/s40729-024-00572-9","DOIUrl":"10.1186/s40729-024-00572-9","url":null,"abstract":"<p><strong>Purpose: </strong>To review the current literature to answer the focused question: in the experimental pig model (population), which types of peri-implant bone defects (exposure) have been used evaluate different modes of therapy and what is their capacity for spontaneous healing and regeneration (outcome)?</p><p><strong>Methods: </strong>Following PRISMA guidelines, electronic databases were searched for studies reporting peri-implant bone defects in the maxillae or mandibles of pigs. Those studies which reported a control group of untreated defects with assessment of spontaneous regeneration [new bone area (BA)] and/or re-osseointegration [new bone-to-implant contact (BIC)] via quantitative radiography or histomorphometry were included in a random effects meta-analysis for the outcomes BA and BIC.</p><p><strong>Results: </strong>Overall, 21 studies, mostly performed in the mandibles of minipigs, were included. Most studies reported 'acute' intrabony (circumferential and/or dehiscence; n = 12) or supra-alveolar defects (horizontal; n = 4). Five studies attempted to induce 'chronic' peri-implantitis lesions using ligatures with conflicting results. Meta-analyses revealed pooled estimates (with 95% confidence intervals) of 48.07% BIC (30.14-66%) and 64.31% BA (42.71-85.91%) in intrabony defects, and 52.09% BIC (41.83-62.35%) and 28.62% BA (12.97-44.28%) in supra-alveolar defects. Heterogeneity in the meta-analysis was high (I<sup>2</sup> > 90%).</p><p><strong>Conclusion: </strong>Current evidence for peri-implant bone regeneration in pigs is mainly based on acute intrabony defects, which demonstrate a high capacity for spontaneous regeneration and re-osseointegration. The evidence for chronic peri-implantitis is limited and does not clearly indicate a spontaneous progression of the disease in this animal model.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"55"},"PeriodicalIF":3.1,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan-Tobias Weitkamp, Adrian Hogreve, Johannes Spille, Salih Veziroglu, Oral Cenk Aktas, Christian Flörke, Kim Rouven Liedtke, Jörg Wiltfang, Aydin Gülses
{"title":"Effectiveness of cold atmospheric plasma in decontaminating enterococcus faecalis colonized collagen and PTFE membranes used in guided bone regeneration: a comparative in vitro investigation.","authors":"Jan-Tobias Weitkamp, Adrian Hogreve, Johannes Spille, Salih Veziroglu, Oral Cenk Aktas, Christian Flörke, Kim Rouven Liedtke, Jörg Wiltfang, Aydin Gülses","doi":"10.1186/s40729-024-00576-5","DOIUrl":"10.1186/s40729-024-00576-5","url":null,"abstract":"<p><strong>Purpose: </strong>Wound healing disorders caused by bacterial infections in dental surgery, especially where membranes are used, are a common issue in oral surgery. Cold atmospheric plasma (CAP) offers a non-invasive solution for surface decontamination, including dental implants. The aim of this study was to evaluate the antibacterial effectiveness of CAP on various clinically applied membranes made of collagen and polytetrafluoroethylene (PTFE).</p><p><strong>Materials and methods: </strong>To assess the antibacterial properties of CAP, enterococcus faecalis were seeded on different membranes: Memlock (collagen), Memlock Pliable (collagen), Agronaut (collagen), and PermaPro (PTFE); n = 4. After in vitro cultivation for 6 days, CAP using a kINPen<sup>®</sup> MED with an output of 5 W was applied 5 min and 10 min. Bacterial colony-forming units (CFU) were quantified to detect decontamination effectiveness. In addition, live and dead staining as well as scanning electron microscopy (SEM) of membranes was performed for validation and surface texture analysis.</p><p><strong>Results: </strong>Bacterial colonization was highest on collagen-based membranes (CFU Memlock: 14.38 ± 8.91). The results showed that CAP significantly reduced bacterial colonization on all membrane types after 10 min application of CAP; Memlock (CFU after 10 min 0.22 ± 0.16^10<sup>6</sup>; p = 0.0256), Argonaut (CFU after 10 min 0.02 ± 0.01^10<sup>6</sup>; p = 0.0129) and PermaPro (complete bacterial decontamination; p = 0.0058). This was paralleled by fluorescence and scanning electron microscopy. CAP was most effective on smooth membrane surfaces as SEM revealed.</p><p><strong>Conclusion: </strong>CAP thus offers a non-invasive, cost-effective method to reduce bacterial infections in guided bone regeneration using membranes.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"53"},"PeriodicalIF":3.1,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nengwen Huang, Yang Li, Wen Li, Rui Zhao, Yanjing Ou, Jiang Chen, Jinjin Li
{"title":"The clinical efficacy of laser in the nonsurgical treatment of peri-implantitis: a systematic review and meta-analysis.","authors":"Nengwen Huang, Yang Li, Wen Li, Rui Zhao, Yanjing Ou, Jiang Chen, Jinjin Li","doi":"10.1186/s40729-024-00570-x","DOIUrl":"10.1186/s40729-024-00570-x","url":null,"abstract":"<p><strong>Objective: </strong>To systematically assess studies regarding the efficacy of lasers in the nonsurgical treatment of peri-implantitis.</p><p><strong>Methods: </strong>Electronic and manual searches were performed by two reviewers independently. Randomized controlled trials (RCTs) comparing lasers vs. mechanical debridement or air abrasive on primary outcome (probing depth (PD)) and secondary outcomes (bone loss, bleeding on probing (BOP), clinical attachment level (CAL) and plaque index (PI)) were included. Data extraction and quality assessment were conducted independently. Weighted mean difference (WMD) or standardized mean difference (SMD) and 95% confidence interval (CI) were calculated for continuous outcomes. Publication bias, leave-one-out analysis and GRADE assessment were conducted.</p><p><strong>Result: </strong>13 eligible publications were included in the review and 12 in the meta-analysis. Solid-state lasers significantly improved in PD (WMD = -0.39, 95% CI (-0.70, -0.09), p = 0.01, moderate-certainty evidence), BOP (SMD =-0.76, 95% CI (-1.23, -0.28), p = 0.002, moderate-certainty evidence) and CAL (WMD =-0.19, 95% CI (-0.39, -0.00), p = 0.05, moderate-certainty evidence), but not in bone loss (WMD = 0.03, 95% CI (-0.13, 0.18), p = 0.74, low-certainty evidence) and PI (SMD =-0.19, 95% CI (-0.42, 0.04), p = 0.11, moderate-certainty evidence) compared with the control group. However, the diode lasers showed no clinical advantages. No publication bias was detected, and leave-one-out analysis confirmed the robustness of findings.</p><p><strong>Conclusion: </strong>In the nonsurgical treatment of peri-implantitis, solid-state lasers yielded positive influence in term of PD, BOP and CAL, while diode laser provided no beneficial effect. Future well-designed large RCTs are still needed, considering the limitations of included studies.</p><p><strong>Clinical relevance: </strong>This review aimed to guide clinicians in choosing the appropriate laser for peri-implantitis, enhancing treatment strategies and attaining better outcomes.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"54"},"PeriodicalIF":3.1,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ausra Ramanauskaite, Katharina Melissa Müller, Carla Schliephake, Karina Obreja, Amira Begic, Iulia Dahmer, Puria Parvini, Frank Schwarz
{"title":"Volumetric changes of porcine collagen matrix and free gingival grafts for soft-tissue grafting to increase the width of keratinized tissue around dental implants: a retrospective clinical study.","authors":"Ausra Ramanauskaite, Katharina Melissa Müller, Carla Schliephake, Karina Obreja, Amira Begic, Iulia Dahmer, Puria Parvini, Frank Schwarz","doi":"10.1186/s40729-024-00575-6","DOIUrl":"10.1186/s40729-024-00575-6","url":null,"abstract":"<p><strong>Aim: </strong>To compare three-dimensional changes of aporcine derived collagen matrix (CM) and free gingival grafts (FGG) for increasing keratinized tissue (KT) at dental implants over a 24-month follow-up period.</p><p><strong>Materials and methods: </strong>This retrospective study enrolled 25 patients exhibiting 41 implants with deficient KT width (i.e., < 2 mm) who underwent soft tissue augmentation using either CM (11 patients/15 implants) or FGG (14 patients/26 implants). The primary outcome was tissue thickness change (mm) at treated implant sites between 1- (S0), 12- (S1), and 24-months (S2). Secondary outcome was the changes of KT width over a 24-month follow-up period.</p><p><strong>Results: </strong>Dimensional analyses from S0 to S1 and from S0 to S2 revealed a mean decrease in tissue thickness of -0.05 ± 0.35 mm and - 0.31 ± 0.41 mm in the CM group, and - 0.23 ± 0.38 mm and - 0.22 ± 0.81 mm in the FGG group, with no significant differences found between the groups (S0-S1: p = 0.14, S0-S2: p = 0.58). Within S1 and S2, the CM and FGG groups displayed comparable tissue thickness reduction (CM: -0.32 ± 0.53 mm, FGG: -0.02 ± 0.21 mm; p = 0.07). The FGG group exhibited a significantly greater KT gain 24-months compared to the CM group (CM: 1.50 ± 1.14 mm, FGG: 4.04 ± 1.65 mm; p < 0.001).</p><p><strong>Conclusions: </strong>CM and FGG were associated with comparable three-dimensional thickness changes over a period of 24 months. A significantly wider KT band could be established in the FGG group.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"52"},"PeriodicalIF":3.1,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11557777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anatomical study of pterygoid implants: artery and nerve passage through bone dehiscence of the greater palatine canal.","authors":"Shuichiro Taniguchi, Masahito Yamamoto, Tomohito Tanaka, Tianyi Yang, Genji Watanabe, Yuki Sugiyama, Takahiro Takagi, Gen Murakami, Shogo Hayashi, Shinichi Abe","doi":"10.1186/s40729-024-00560-z","DOIUrl":"10.1186/s40729-024-00560-z","url":null,"abstract":"<p><strong>Purpose: </strong>Pterygoid implants are an alternative approach to avoid sinus-lifting or other grafting procedures. During pterygoid implant placement, dental surgeons risk damaging the greater palatine canal (GPC). However, they do not have sufficient reasons to avoid GPC injury. This study performed a detailed morphological analysis of the GPC to determine susceptibility to damage during pterygoid implant surgery.</p><p><strong>Methods: </strong>To understand the detailed morphology of the GPC, gross anatomical analysis, histological analysis, and bone morphometry via micro-computed tomography were performed.</p><p><strong>Results: </strong>We found that the medial wall of the GPC communicated with the nasal cavity through the bone dehiscence. The dehiscence appeared near the inferior nasal concha in 72.4% of the cadavers. The nerve and artery passed from the GPC to the nasal mucous membrane through the dehiscence. Given that the greater palatine nerve passed medial to the descending palatine artery in the GPC, the descending palatine artery is damaged first rather than the greater palatine nerve during pterygoid implant surgery.</p><p><strong>Conclusions: </strong>Dental surgeons who penetrate the GPC using an implant body may extend the bleeding to the nasal mucosa, which seems to spread the inflammation to the nasal cavity.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"51"},"PeriodicalIF":4.3,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study of peri-implant tissue clinical parameters in patients starting anti-osteoporosis medication after existing implant function: a prospective cohort study.","authors":"Keisuke Seki, Takaaki Tamagawa, Hiroyasu Yasuda, Soichiro Manaka, Daisuke Akita, Atsushi Kamimoto, Yoshiyuki Hagiwara","doi":"10.1186/s40729-024-00569-4","DOIUrl":"10.1186/s40729-024-00569-4","url":null,"abstract":"<p><strong>Purpose: </strong>Recently, rare cases of medication-related peri-implant osteonecrosis of the jaw (PI-MRONJ) have been reported. In patients with functional implants who begin using anti-osteoporosis medications (AOMs) after implantation, PI-MRONJ is unpredictable and poses a significant threat to the patient. In this study, we aimed to evaluate the impact of AOMs on peri-implant tissues and to examine risk factors for peri-implantitis, a presumed trigger for PI-MRONJ.</p><p><strong>Methods: </strong>The study cohort consisted of patients who underwent implant maintenance treatment between January 2016 and February 2024. Patients were divided into AOM users (AOM group) and controls (control group). Clinical parameters were statistically evaluated, including implant probing depth (iPPD), implant bleeding on probing (iBoP), marginal bone resorption (MBL), and mandibular cortical index (MCI) measured at baseline and at the last visit. Risk factors were examined by multivariate analysis for adjusted odds ratios.</p><p><strong>Results: </strong>A total of 94 patients (35 male, 59 female) with 270 implants were recruited. The AOM group had 93 implants (24 patients). Comparison of clinical parameters showed significantly greater changes in iBoP (p = 0.000768) and MBL (p = 0.000863) scores over time in the AOM group than in the control group. Risk factors for peri-implantitis were a history of moderate or severe periodontal disease (OR: 15.8, 95% CI 3.6-69.3, p = 0.000256) and MCI class 3 (OR: 3.3, 95% CI 1.4-7.8, p = 0.00534).</p><p><strong>Conclusions: </strong>In implant treatment of AOM users, special attention should be paid to local inflammation, which is presumed to be the cause of PI-MRONJ.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"50"},"PeriodicalIF":3.1,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral function status of older patients seeking dental implant treatment.","authors":"Risako Taue, Tokiko Osawa, Yoshiki Uchida, Myu Hayashi, Kentaro Kitakabu, Yuji Sato, Junichi Furuya","doi":"10.1186/s40729-024-00571-w","DOIUrl":"10.1186/s40729-024-00571-w","url":null,"abstract":"<p><strong>Purpose: </strong>In recent years, dental implant treatment has become an option for prosthetic treatment for missing teeth and is often performed in older patients. However, the complex oral functional decline in old age presents challenges in terms of frailty prevention, making oral function management after prosthetic treatment crucial. Nonetheless, the actual status of oral function in older patients seeking dental implant treatment remains unclear. In this study, we aimed to assess the oral function status of older patients seeking dental implant treatment.</p><p><strong>Methods: </strong>Among patients receiving prosthetic treatment for missing teeth, 227 older patients (111 in the pre-dental implant group and 116 in the pre-bridge/denture group) who underwent a thorough examination of their oral function were included in this study. Age, sex, comorbidities, smoking status, number of functional teeth, and occlusal support status were obtained from the medical records. Statistical analyses were performed using the t-test, chi-square test, and logistic regression (p < 0.05).</p><p><strong>Results: </strong>Compared with the pre-bridge/denture group, the pre-dental implant group had significantly better oral hygiene, occlusal force, tongue-lip motor function, tongue pressure, masticatory function, and swallowing function and a significantly lower prevalence of oral hypofunction. Older age and decreased occlusal support were associated with the diagnosis of oral hypofunction, even after adjusting for confounding factors including prosthetic treatment.</p><p><strong>Conclusions: </strong>Although older patients seeking dental implant treatment have a higher oral function than those seeking general prosthetic treatment, older age and a lower number of occlusal supports suggest that appropriate oral function management is needed.</p>","PeriodicalId":14076,"journal":{"name":"International Journal of Implant Dentistry","volume":"10 1","pages":"49"},"PeriodicalIF":3.1,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}