International Journal of Biomaterials最新文献_第8页

One-Year Multicenter Randomised Controlled Trial Comparing OT Equator® and Locator Attachments to Retain an Early Loaded Implant Overdenture on Two Implants. 为期一年的多中心随机对照试验比较OT Equator®和Locator附着体在两个种植体上保留早期加载种植覆盖义齿的效果。

IF 3.1

International Journal of Biomaterials Pub Date : 2023-01-01 DOI: 10.1155/2023/2745262

Marco Tallarico, Luca Fiorillo, Marco Montanari, Roberto Scrascia, Corina Marilena Cristache, Emiliano Ferrari, Alessio Casucci, Erta Xhanari, Saturnino Marco Lupi, Irene Ieria, Edoardo Baldoni, Ruggero Rodriguez Y Baena, Gabriele Cervino

{"title":"One-Year Multicenter Randomised Controlled Trial Comparing OT Equator® and Locator Attachments to Retain an Early Loaded Implant Overdenture on Two Implants.","authors":"Marco Tallarico, Luca Fiorillo, Marco Montanari, Roberto Scrascia, Corina Marilena Cristache, Emiliano Ferrari, Alessio Casucci, Erta Xhanari, Saturnino Marco Lupi, Irene Ieria, Edoardo Baldoni, Ruggero Rodriguez Y Baena, Gabriele Cervino","doi":"10.1155/2023/2745262","DOIUrl":"https://doi.org/10.1155/2023/2745262","url":null,"abstract":"This investigation aimed to compare the effectiveness of the OT Equator® (Rhein, Bologna, Italy) and the Locator attachment systems used to retain early loaded implant-retained overdentures. This study was designed as a multicenter randomised controlled trial of parallel groups. After implant placement, the patients were randomised to receive OT Equator® attachments in the test group or Locator attachments in the control group. The outcome measures were implant and prosthetic success and survival rates, any biological and technical complication, marginal bone loss, patients' satisfaction, and periodontal parameters. Overall, 42 patients were consecutively enrolled and treated. One implant was lost in the control group, while no implants were lost in the test group. No prostheses failed in both groups. Only a few complications were experienced in both groups. The main was represented by loss of retention of the attachments (retentive caps). The OT Equator® attachment showed statistically lower periodontal parameters. In conclusion, both attachment systems were suitable for overdenture implant retention.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2023 ","pages":"2745262"},"PeriodicalIF":3.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9823634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Polyethylene Glycol-Modified Chitosan Scaffolds on the Proliferation and Differentiation of Osteoblasts. 聚乙二醇修饰壳聚糖支架对成骨细胞增殖分化的影响。

IF 3.1

International Journal of Biomaterials Pub Date : 2023-01-01 DOI: 10.1155/2023/4864492

Wei-Bor Tsai, Ibrahim Nasser Ahmed

{"title":"The Impact of Polyethylene Glycol-Modified Chitosan Scaffolds on the Proliferation and Differentiation of Osteoblasts.","authors":"Wei-Bor Tsai, Ibrahim Nasser Ahmed","doi":"10.1155/2023/4864492","DOIUrl":"https://doi.org/10.1155/2023/4864492","url":null,"abstract":"The objective of this study was to investigate the influence of polyethylene glycol (PEG) incorporated chitosan scaffolds on osteoblasts proliferation and differentiation. The chitosan polymer was initially modified by the predetermined concentration of the photoreactive azido group for UV-crosslinking and with RGD peptides (N-acetyl-GRGDSPGYG-amide). The PEG was mixed at different ratios (0, 10, and 20 wt%) with modified chitosan in 96-well tissue culture polystyrene plates to prepare CHI-100, CHI-90, and CHI-80 scaffolds. PEG-containing scaffolds exhibited bigger pore size and higher water content compared to unmodified chitosan scaffolds. After 10 days of incubation, the cell number of CHI-90 (1.1 × 106 cells/scaffold) surpasses that of CHI-100 (9.2 × 105 cells/scaffold) and the cell number of CHI-80 (7.6 × 105 cells/scaffold) were significantly lower. The ALP activity of CHI-90 was the highest on the fifth day indicating the favored osteoblasts' early-stage differentiation. Moreover, after 14 days of osteogenic culture, calcium deposition in the CHI-90 scaffolds (2.7 μmol Ca/scaffold) was significantly higher than the control (2.2 μmol Ca/scaffold) whereas on CHI-80 was 1.9 μmol/scaffold. The results demonstrate that PEG-incorporated chitosan scaffolds favored osteoblasts proliferation and differentiation; however, mixing relatively excess PEG (≥20% wt.) had a negative impact on osteoblasts proliferation and differentiation.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2023 ","pages":"4864492"},"PeriodicalIF":3.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10519052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Titanium Coated with Graphene and Niobium Pentoxide for Biomaterial Applications. 用于生物材料应用的涂有石墨烯和五氧化二铌的钛。

IF 3

International Journal of Biomaterials Pub Date : 2022-11-30 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2786101

Hazel Paloma Reis Corado, Francielly Moura de Souza Soraes, Dyanni Manhães Barbosa, Andreza Menezes Lima, Carlos Nelson Elias

{"title":"Titanium Coated with Graphene and Niobium Pentoxide for Biomaterial Applications.","authors":"Hazel Paloma Reis Corado, Francielly Moura de Souza Soraes, Dyanni Manhães Barbosa, Andreza Menezes Lima, Carlos Nelson Elias","doi":"10.1155/2022/2786101","DOIUrl":"10.1155/2022/2786101","url":null,"abstract":"Graphene and niobium oxide are used in biomaterial coatings. In this work, commercially pure titanium (cp Ti) was coated with graphene oxide (GO), niobium pentoxide (Nb2O5), and a mixture of both materials (NbGO) by the electrochemical deposition method. The surface morphology, roughness, wettability, and degradation of coated and uncoated samples were analyzed by scanning electron microscopy, interferometry, and contact angle. The results showed that the specimens coated with NbGO (cp Ti-NbGO) showed the highest surface roughness (Ra = 0.64 μm) and were hydrophobic. The contact (θ) angle between water and the surface of uncoated specimens (cp Ti), coated with GO (cp Ti-GO), coated with a mixture with GO and Nb2O5) (cp Ti-NbGO), and coated with Nb2O5 were 50.74°, 44.35°, 55.86°, and 100.35°, respectively. The electrochemical corrosion tests showed that coating with graphene oxide increased the corrosion resistance and coating with Nb2O5 decreased the corrosion resistance. The negative effect of the effect of Nb2O5 coating in corrosion resistance compensated for the release of Nb2O5, which helps osseointegration, increasing cell viability, and proliferation of osteoblasts. The NbGO coating may be a good way to combine the bactericidal effect of graphene oxide with the osseointegration effect of Nb2O5.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2022 ","pages":"2786101"},"PeriodicalIF":3.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10337284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications. 水凝胶在再生医学中的应用进展:性质和生物医学应用。

IF 3.1

International Journal of Biomaterials Pub Date : 2022-11-07 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3606765

Andrea Revete, Andrea Aparicio, Bruno A Cisterna, Javier Revete, Luis Luis, Ernesto Ibarra, Edwin A Segura González, Jay Molino, Diego Reginensi

{"title":"Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications.","authors":"Andrea Revete, Andrea Aparicio, Bruno A Cisterna, Javier Revete, Luis Luis, Ernesto Ibarra, Edwin A Segura González, Jay Molino, Diego Reginensi","doi":"10.1155/2022/3606765","DOIUrl":"https://doi.org/10.1155/2022/3606765","url":null,"abstract":"Due to their particular water absorption capacity, hydrogels are the most widely used scaffolds in biomedical studies to regenerate damaged tissue. Hydrogels can be used in tissue engineering to design scaffolds for three-dimensional cell culture, providing a novel alternative to the traditional two-dimensional cell culture as hydrogels have a three-dimensional biomimetic structure. This material property is crucial in regenerative medicine, especially for the nervous system, since it is a highly complex and delicate structure. Hydrogels can move quickly within the human body without physically disturbing the environment and possess essential biocompatible properties, as well as the ability to form a mimetic scaffold in situ. Therefore, hydrogels are perfect candidates for biomedical applications. Hydrogels represent a potential alternative to regenerating tissue lost after removing a brain tumor and/or brain injuries. This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":" ","pages":"3606765"},"PeriodicalIF":3.1,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40469591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Zinc Oxide Nanoparticles as Diagnostic Tool for Cancer Cells. 氧化锌纳米颗粒作为癌细胞的诊断工具。

IF 3.1

International Journal of Biomaterials Pub Date : 2022-11-02 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2807644

Sumayah Ibraheem, Afraa Ali Kadhim, Kadhim Ali Kadhim, Ihssan A Kadhim, Majid Jabir

{"title":"Zinc Oxide Nanoparticles as Diagnostic Tool for Cancer Cells.","authors":"Sumayah Ibraheem, Afraa Ali Kadhim, Kadhim Ali Kadhim, Ihssan A Kadhim, Majid Jabir","doi":"10.1155/2022/2807644","DOIUrl":"https://doi.org/10.1155/2022/2807644","url":null,"abstract":"ZnO nanoparticles have various characteristics that make them attractive to be used in many medical applications like a cancer diagnosis. It can be used as a nanoprobe for targeting different types of cancer cells in vitro as a cancer cell recognition system. The present study aims to investigate the permeability of ZnO NPs through both normal and cancerous cell lines in humans. In vitro experiments for ZnO NPs inside the environment of living cells have been described, which would contribute to the visualization of nanoparticles as cancer diagnostic and scanning techniques. MCF7, AMJ13, and RD cancer cells, and also the normal breast cell line HBL, were used in in vitro imaging experiments. The findings revealed that ZnO NPs specifically incorporated within tumor cells while accumulating less inside normal cells. Our findings show that ZnO NPs may be identified inside cancer cells after 1 h of exposure and can endure up to 3 h, providing them appropriate for tumor cell imaging. The findings showed that ZnO NPs might be employed as an alternate fluorophore for diagnostic imaging in the early identification of solid cancers. Therefore, here we studied in vitro applications of ZnO NPs and their beneficial use as a diagnostic tool for cancer cell lines rather than normal cells. Taken together, ZnO NPs can be used as good targeting NPs for the development of imaging agents for early diagnosis of cancers.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":" ","pages":"2807644"},"PeriodicalIF":3.1,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40469588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Color Matching of Universal Shade Resin-Based Composite with Natural Teeth and Its Stability before and after In-Office Bleaching. 通用色光树脂基复合材料与天然牙的配色及办公室漂白前后的稳定性

IF 3.1

International Journal of Biomaterials Pub Date : 2022-10-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8420890

AlHanouf AlHabdan, Ahoud AlShamrani, Randa AlHumaidan, AlJohrah AlFehaid, Sara Eisa

{"title":"Color Matching of Universal Shade Resin-Based Composite with Natural Teeth and Its Stability before and after In-Office Bleaching.","authors":"AlHanouf AlHabdan, Ahoud AlShamrani, Randa AlHumaidan, AlJohrah AlFehaid, Sara Eisa","doi":"10.1155/2022/8420890","DOIUrl":"https://doi.org/10.1155/2022/8420890","url":null,"abstract":"Objectives: Esthetics is an essential issue for the long-term success of composite resin restoration. Therefore, this study aimed to view the esthetics of universal shade composite resin restorations and to assess its color matching before and after bleaching.Materials and methods: Overall, 40 freshly extracted premolars were mounted in an acrylic resin mold, and Class V cavities were then prepared and restored by OMNICHROMA composite (Tokuyama Dental, Tokyo, Japan) and polished with 2-step polishing system. Baseline color analysis was performed using VITA Easyshade V digital spectrophotometer, and another color analysis was carried out 24 hours after storage in distilled water. In-office bleaching was carried out, and color measurements were taken after bleaching and 2 weeks postbleaching. The data were statistically analyzed using SPSS 26.0 Windows version statistical software. Changes were considered statistically significant at P = 0.05.Results: ΔE value of OMNICHROMA restoration before and after restoration was 6.474, 3.529 before and after bleaching, and 3.651 two-weeks postbleaching. In-office bleaching was effective in bleaching the OMNICHROMA specimens as the restoration showed positive ΔL ∗ values, which indicated that the specimens were lighter in color after bleaching; however, the bleaching effect was not maintained after 2 weeks.Conclusion: OMNICHROMA universal shade composite resin restoration showed different color matching values with the adjacent enamel of class Vs. The material appeared lighter in shade postbleaching, and the color change was not maintained 2 weeks postbleaching.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":" ","pages":"8420890"},"PeriodicalIF":3.1,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40670499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Comparative Study of Biotin and Hydroxyapatite on Biological Properties of Composite Coating. 生物素与羟基磷灰石对复合涂层生物学性能的比较研究。

IF 3.1

International Journal of Biomaterials Pub Date : 2022-09-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8802111

Qahtan A Hamad, Fatimah J Al-Hasani, Noor K Faheed

{"title":"Comparative Study of Biotin and Hydroxyapatite on Biological Properties of Composite Coating.","authors":"Qahtan A Hamad, Fatimah J Al-Hasani, Noor K Faheed","doi":"10.1155/2022/8802111","DOIUrl":"https://doi.org/10.1155/2022/8802111","url":null,"abstract":"The ultimate goal of using biomaterials is to improve human health by restoring the function of natural living tissues and organs in the body. The present work aims to modify the composite coating layer properties by using two different types of bioactive reinforcing materials (biotin and hydroxyapatite) particles in different percentages (5% and 10%). Coatings were applied onto commercially pure Ti, SS 316 L, and SS 304 substrates by the dip-coating method. Characterization of samples includes microstructure observation by field emission scanning electron microscopy (FE-SEM), contact angle measurement (wettability), and MTT. The results show the addition of metallic particles (bioparticles) (hydroxyapatite particles, biotin) at 5 Vol. % improved the whole properties of composite materials. Using different particles' scale size aids to enhance the combinations in the alginate matrix producing a dual effect on composite film properties. In addition, the inclusion of metallic particles has to increase the wettability by reducing the contact angle. At the same time, MTT graphs revealed that after 3 days of exposure in MG-63 cells, 316 L SS alloys' surface following pack adhesion became more active.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":" ","pages":"8802111"},"PeriodicalIF":3.1,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33490512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea. 油橄榄生物合成银纳米颗粒的优化、表征及抗癌潜力。

IF 3.1

International Journal of Biomaterials Pub Date : 2022-09-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6859637

Afnan I Felimban, Njud S Alharbi, Nehad S Alsubhi

引用次数: 2

Histological Evaluation of the Effect of Local Application of Punica granatum Seed Oil on Bone Healing. 局部应用石榴籽油对骨愈合影响的组织学评价。

IF 3.1

International Journal of Biomaterials Pub Date : 2022-09-24 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4266589

Ibrahim Fouad Mohamed, Ban A Ghani, Abdalbseet A Fatalla

{"title":"Histological Evaluation of the Effect of Local Application of Punica granatum Seed Oil on Bone Healing.","authors":"Ibrahim Fouad Mohamed, Ban A Ghani, Abdalbseet A Fatalla","doi":"10.1155/2022/4266589","DOIUrl":"https://doi.org/10.1155/2022/4266589","url":null,"abstract":"Background: Bone healing is a complex and dynamic process that represents a well-orchestrated series of biological events of cellular recruitment, proliferation, and differentiation. The use of medicinal plants in bone healing has attracted increasing interest because of their lower side effects. Punica granatum seed oil (PSO) contains high levels of phenolic compounds, promotes osteoblast function, and plays an important role in bone remodeling. A gelatin sponge (Spongostan) is a hemostatic agent that is extensively applied as scaffolds in engineering and as drug carriers in the medical field. This study aimed to evaluate the effectiveness of PSO for bone healing enhancement. Twenty adult male New Zealand rabbits, weighing an average of 1.5-2 kg, were used in this study. Three intrabony holes were created in the tibiae of each animal, which were filled with a gelatin sponge (GS group) and combined gelatin sponge and PSO (GS/PSO group). Holes without material application were designated as the control group (C group). The animals were sacrificed at the healing duration (2-4 weeks) to prepare bone specimens for histological and histomorphometric analyses.Results: Histological findings indicated that the bone defects in the GS/PSO group showed more bone formation, mineralization, and maturation compared with the C and GS groups. Multiple group differences for bone cells showed a highly significant difference among all groups in the 2- and 4-week healing periods except for the C/GS and GS/GS/PSO groups at 4-weeks duration. Furthermore, highly significant results were obtained between both durations regarding the trabecular area, trabecular number, and bone marrow area.Conclusion: The study revealed that the combined application of GS and PSO was more effective in enhancing bone regeneration and accelerating bone healing compared with the other groups.","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":" ","pages":"4266589"},"PeriodicalIF":3.1,"publicationDate":"2022-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9526640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33486549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Synthesis of Carbon-Encapsulated Magnetic Iron Oxide Nanocomposites for Bioapplication. 生物应用碳包封磁性氧化铁纳米复合材料的合成。

IF 3.1

International Journal of Biomaterials Pub Date : 2022-09-20 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3302082

Wubshet Mekonnen Girma

引用次数: 2