International Journal of Biomaterials最新文献

{"title":"Effect of <i>Moringa oleifera</i> Protein-Coated Gold Nanoparticles as Naturally Derived Disruptors of Biofilms.","authors":"Lakshmi Sudhir Menon, Narendranath Ghosh, Sumit Biswas","doi":"10.1155/ijbm/1381604","DOIUrl":"10.1155/ijbm/1381604","url":null,"abstract":"<p><strong>Background: </strong>Microbes having affinity to metallic surfaces develop a highly structured and sessile colony known as biofilms which poses significant challenges to the domain of implant surgery. Biofilm-mediated infections and the associated burden have prompted the search for multipronged approaches to tackle the problem. Gram-positive pathogens, most notably <i>Staphylococcus aureus</i>, has been known to colonize human tracts and form biofilms on implants and prosthetic devices. Antibiotic tolerance, drug efflux, and recalcitrance to the host immune response have added to the existing predicament of the biofilm infections.</p><p><strong>Objective: </strong>The search for inexpensive but effective avenues for combating biofilms has led to the use of metal nanoparticles conjugated with plant-derived proteins.</p><p><strong>Methods: </strong>In this study, a protein from <i>Moringa oleifera</i> leaf extract, p62, which has been previously identified to have antibiofilm properties, was conjugated with spherical gold nanoparticles (AuNPs) to target <i>S. aureus</i> biofilm formation.</p><p><strong>Results: </strong>The adsorption of p62 on the AuNPs was confirmed through microscopy, and the kinetics of binding was determined by plasmon resonance. The p62 coated AuNPs remained stable in solution and caused the successful disintegration of mature biofilms, more efficiently than the protein alone. The p62-AuNPs were also found to disrupt the morphology of the cocci and cause cell death as evidenced from the live/dead cell imaging through confocal microscopy. The protein and the nanoparticle were not cytotoxic to C2C12 human myoblast cell lines, affirming their suitability to be used on implants.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2026 ","pages":"1381604"},"PeriodicalIF":4.5,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12892876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanocomposite Bone Scaffolds Based on Magnesium Alloy: A Detailed Investigation of Their In-Vitro Biodegradation Performance.","authors":"Adithya Garimella, Firoz Alam Faroque, Subrata Bandhu Ghosh, Sanchita Bandyopadhyay-Ghosh","doi":"10.1155/ijbm/9617232","DOIUrl":"10.1155/ijbm/9617232","url":null,"abstract":"<p><p>Polymeric biomaterials and their composites have been extensively explored for orthopaedic applications; however, their inadequate mechanical performance significantly restricts their use in load-bearing environments. Metallic biomaterials, by contrast, offer superior mechanical strength and structural stability. Among them, magnesium (Mg) has emerged as a particularly attractive candidate for temporary orthopaedic implants owing to its elastic modulus and density being close to those of natural bone, thereby minimising stress shielding. In addition, Mg inherently fulfils two critical requirements for orthopaedic implants-biocompatibility and biodegradability. In this study, a bioactive magnesium-alloy-based nanocomposite scaffold was engineered to overcome the limitations of conventional biomaterials while closely replicating the porous microarchitecture of human bone. A novel bioactive glass-ceramic, nano-fluorcanasite (n-FC), was incorporated into the Mg-alloy matrix to enhance osteogenic activity and accelerate bone tissue regeneration. The introduction of an interconnected porous structure was designed to promote efficient nutrient diffusion, facilitate metabolic waste removal and reduce implant density. Furthermore, the controlled addition of selected alloying elements in specific weight fractions effectively moderated the degradation kinetics of the Mg-based scaffold. The nanocomposite scaffolds were fabricated using a powder metallurgy route followed by sintering. Tailored porosity was achieved through the controlled incorporation of carbamide particles as a space-holding agent. The in vitro degradation behaviour of the scaffolds was systematically evaluated using a weight-change method after immersion in phosphate-buffered saline (PBS) for predetermined durations. The results demonstrate that, compared with unalloyed magnesium, the degradation rate of the nanocomposite scaffolds can be precisely and consistently regulated, highlighting their potential as mechanically competent, bioactive and biodegradable candidates for orthopaedic implant applications.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2026 ","pages":"9617232"},"PeriodicalIF":4.5,"publicationDate":"2026-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12884007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herbal Cocktail Hydrogel Film (<i>Garcinia mangostana</i>, <i>Centella asiatica</i>, and <i>Chromolaena odorata</i> Extracts): A Novel Wound Dressing Approach.","authors":"Tanikan Sangnim, Chonlada Panpipat, Suwisit Manmuan, Nontanat Leehueng, Wasutthanat Suphan, Chanapa Thuenaram, Kampanart Huanbutta","doi":"10.1155/ijbm/5576769","DOIUrl":"10.1155/ijbm/5576769","url":null,"abstract":"<p><p>Chronic and infected wounds remain a significant clinical challenge due to delayed healing and the risk of microbial contamination. Conventional wound dressings often fail to provide comprehensive therapeutic support, necessitating the development of advanced multifunctional materials. This study aimed to develop a multifunctional hydrogel wound dressing incorporating herbal extracts from <i>Garcinia mangostana</i>, <i>Centella asiatica</i>, and <i>Chromolaena odorata</i>, targeting key biological functions essential for wound healing. The novelty lies in the synergistic combination of these three extracts to address multistage healing needs and the systematic optimization of the polymer matrix via a design-of-experiments (DOE) approach. The extracts were obtained through optimized extraction techniques and quantified using HPLC, confirming the presence of bioactive markers. Pharmacological evaluations revealed distinct and synergistic activities: <i>Garcinia mangostana</i> extract showed potent antibacterial effects against <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i> (MIC of 7.8 μg/mL) and strong antioxidant capacity (ABTS IC₅₀ of 26.5 μg/mL). In contrast, <i>Centella asiatica</i> extract demonstrated high biocompatibility on human keratinocytes (IC₅₀ of 736.11 μg/mL), while <i>Chromolaena odorata</i> provided significant anti-inflammatory and hemostatic benefits. A hydrogel base was developed using a polyvinyl alcohol (PVA)/sodium carboxymethyl cellulose (SCMC) polymer matrix, optimized via factorial design for texture, swelling ratio, and moisture retention. The extract-loaded hydrogel maintained skin-compatible pH, showed improved tensile strength and flexibility, and exhibited superior swelling capacity (188.7%) compared to the blank (120.3%). Overall, the formulated hydrogel demonstrates promise as an effective wound dressing with antibacterial, anti-inflammatory, and antioxidant properties, suitable for chronic or infected wound applications.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2026 ","pages":"5576769"},"PeriodicalIF":4.5,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12860223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative Medicine Advancements: A Systematic Review on the Combinatory Effect of Platelet-Rich Plasma/Fibrin and Collagen.","authors":"Nunzia Gallo, Chiara Kodra, Domenico Rocco, Cosimo Saponaro, Alessandro Sannino, Luca Salvatore","doi":"10.1155/ijbm/1679626","DOIUrl":"10.1155/ijbm/1679626","url":null,"abstract":"<p><strong>Background: </strong>The regeneration of injured tissues remains a major clinical challenge. Among emerging biomaterials, collagen with platelet-rich plasma (PRP) or platelet-rich fibrin (PRF) showed promising outcomes, individually and in combination.</p><p><strong>Objective: </strong>To systematically review clinical evidence on the efficacy, applications, and safety of PRP/PRF and collagen for regenerative medicine applications.</p><p><strong>Methods: </strong>A systematic literature search was conducted in PubMed, Wiley Online Library, Google Scholar, and ClinicalTrials.gov (search date: September, 2025). Inclusion criteria: clinical studies evaluating PRP/PRF and collagen formulations. Exclusion: preclinical only or nonoriginal research. Data were synthesized narratively.</p><p><strong>Results: </strong>Twenty-six clinical studies were included. Applications included gingival recession, periodontitis, tendon injuries, bone regeneration, peripheral nerve repair, and chronic ulcers. Most studies reported positive outcomes, though many lacked control groups or had small sample sizes. No serious adverse events were reported.</p><p><strong>Conclusion: </strong>PRP/PRF and collagen show potential for various clinical applications in regenerative medicine. However, randomized clinical studies are necessary to demonstrate their superiority to standard treatment and to standardize protocols.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2026 ","pages":"1679626"},"PeriodicalIF":4.5,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12794683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145964952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Extracellular Vesicles (BEVs) Derived From <i>Lactococcus lactis</i> as Multimodal Drug Delivery Platforms.","authors":"Sushmita Das, Subrata Das, Subhadeep Gupta, Afruja Khan, Pradip Kumar Tarafdar, Amirul Islam Mallick","doi":"10.1155/ijbm/3141223","DOIUrl":"10.1155/ijbm/3141223","url":null,"abstract":"<p><p>Advances in drug delivery technologies involve the extracellular vesicles as a promising bioactive drug delivery vehicle expected to improve targeted therapeutic delivery in pharmaceutical innovations. Recently, Gram-negative bacterial extracellular vesicles (outer membrane vesicles or OMVs) have gained attention for their role in host-microbe interactions and potential in drug delivery. Bacterial extracellular vesicle (BEV) shedding is a conserved mechanism of intra- and interspecies communication, providing critical insights into host-microbe interactions. However, the biogenesis and compositional diversity of BEVs produced by Gram-positive bacteria remain underexplored. Understanding the translational application potential of BEVs remains elusive due to the suboptimal isolation of BEVs and limited structural-functional characterization. A comprehensive study to develop BEVs as delivery vehicles will provide critical insights into the perspective of microbial-host interplay and illuminate the modulation of the drug delivery strategy. Here, using a food-grade probiotic <i>Lactococcus lacti</i>s subsp. <i>cremoris</i> MG1363 (strain NZ9000), we demonstrated that perturbing peptidoglycan biosynthesis with ampicillin, which targets penicillin-binding proteins (PBPs), significantly enhances BEV production. We further explored the interaction between BEVs and host cells through this optimized BEV biogenesis, revealing its cargo-delivering capability. Furthermore, to understand the potential of BEVs as a multimodal drug delivery platform, we target multidrug-resistant microbial pathogens and cancer cell proliferation with drug-encapsulated BEVs. With a generally recognized as safe (GRAS) recognition of <i>L. lactis,</i> we demonstrated that drug-loaded <i>L. lactis</i> BEVs can offer recognizable therapeutic effects. These findings highlight the versatile nature of <i>L. lactis</i> BEVs as stable, safe, natural nanocarriers capable of personalized cargo delivery with broad therapeutic applications.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2025 ","pages":"3141223"},"PeriodicalIF":4.5,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12755118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145889136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sterilization by Ozone: Effects on Electrospun Polycaprolactone Membrane Properties and Cell Viability.","authors":"Taisa L S Farias, Ivanildes Bastos, Joelma Cavalcante Ricardo, Jessica F Cunha, Yonny Romaguera-Barcelay, Ariamna Gandarilla, Karen Segala, Patrícia Puccinelli Orlandi, Rúben Fernandes, Marcos Marques da Silva Paula, Walter Ricardo Brito","doi":"10.1155/ijbm/9230130","DOIUrl":"10.1155/ijbm/9230130","url":null,"abstract":"<p><p>This study focuses on developing and characterizing electrospun polycaprolactone (PCL) membranes as scaffolds for cell growth, leveraging their ability to mimic the extracellular matrix and promote cell proliferation. The membranes were fabricated by electrospinning and sterilized using ozone at room temperature. Comprehensive characterization techniques, including scanning electron microscopy (SEM), contact angle measurements, ultraviolet-visible spectroscopy (UV-Vis), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, and in vitro biocompatibility assays with MRC-5 cells, were employed. The electrospun membranes exhibited uniform fibers with an average diameter of 403 ± 100 nm and demonstrated sterility, with no microbial growth observed after incubation. Contact angle measurements revealed values of 123 ± 0.42° and 123 ± 0.25° for nonsterilized and sterilized membranes, respectively, indicating consistent hydrophobicity. Thermal analyses confirmed the structural stability of PCL membranes, while UV-Vis studies validated their controlled degradation and release kinetics. FTIR and Raman spectroscopy confirmed that ozone sterilization preserved the chemical integrity of the membranes, with no new organic functions observed. Biocompatibility assays demonstrated high cell viability (> 97%) and effective adhesion on the membranes, highlighting their compatibility and suitability for supporting cell proliferation. These results demonstrate the efficacy of ozone sterilization and the potential of electrospun PCL membranes for a wide range of biomedical applications, including tissue engineering, wound healing, and drug delivery systems.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2025 ","pages":"9230130"},"PeriodicalIF":4.5,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12752849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Casein Phosphopeptide-Amorphous Calcium Phosphate and Gallic Acid as a Complementary Approach for the Treatment of Early Enamel Lesions.","authors":"Mahtab Mottaghi, Hossein Bagheri, Sara Majidinia, Abdolrasoul Rangrazi, Ali Faramarzi Garmroodi, Aliakbar Hodjatpanah Montazeri","doi":"10.1155/ijbm/5536375","DOIUrl":"10.1155/ijbm/5536375","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) in combination with gallic acid (GA) compared to their individual effects on improving the microhardness of artificial enamel lesions at different depths from the surface.</p><p><strong>Materials and methods: </strong>Forty enamel blocks were fabricated, with one-third of each block coated in varnish to establish a protected sound zone. The blocks were submerged in a demineralizing solution for 96 h to create artificial enamel lesions. Subsequently, half of the demineralized region was coated with varnish to create a reference demineralized area. The samples were allocated to four groups, with the remaining exposed portions treated with three experimental pastes (CPP-ACP paste, GA paste, and CPP-ACP + GA paste) and one control paste, representing the remineralized area. Vickers microhardness was assessed at depths of 20, 50, 100, 150, and 200 μm from the enamel surface in each region. Data were analyzed utilizing one-way ANOVA, followed by post hoc LSD tests. Cohen's d effect sizes and 95% confidence intervals (CIs) were also calculated to assess the strength of pairwise comparisons.</p><p><strong>Results: </strong>The CPP-ACP + GA paste exhibited the most significant enhancement in enamel microhardness at depths of 20, 50, and 100 μm with large effect sizes. While both CPP-ACP paste and GA paste significantly enhanced microhardness at 20 and 50 μm depths, they did not considerably impact microhardness at 100 μm depth.</p><p><strong>Conclusion: </strong>The combined use of CPP-ACP and GA showed a superior enhancement in the microhardness of artificial enamel lesions compared to the individual application of each agent.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2025 ","pages":"5536375"},"PeriodicalIF":4.5,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12672058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Janus Magnetic Polymeric Colloids Gradient Thin Films of Amino Dextran Coated Core-Shell Poly (Styrene/Divinylbenzene/Methacrylic Acid) for Ultrasensitive Magnetic Resonance Imaging.","authors":"Sundas Khalid, Rafay Naseer, Aqsa Zaheen, Mudassara Saqib, Naveed Ahmed, Abdelhamid Elaissari, Asad Ullah Khan, Kashif Mairaj Deen, Nauman Naseer, Nasir M Ahmad","doi":"10.1155/ijbm/6630827","DOIUrl":"10.1155/ijbm/6630827","url":null,"abstract":"<p><p>The present study focuses on developing novel gradient thin films for surface-based magnetic resonance imaging of fluids such as water. Four types of magnetic-polymer colloids were investigated as T2 contrast agents, including Janus magnetic-polystyrene and core-shell magnetic-poly(styrene/divinylbenzene/methacrylic acid) particles. These colloids were coated with amino dextran to enhance their performance. Key factors such as emulsion composition, particle size, and surface properties were systematically examined. Gradient thin films were fabricated on glass slides using a layer-by-layer self-assembled multilayer (LbL-SAMu) technique. The films consisted of positively charged poly(dimethyl diallyl ammonium chloride) and negatively charged magnetic-polymer colloids. The developed colloids and thin films were characterized by their surface wettability, surface morphology, and zeta potential. These films exhibited relatively improved hydrophilicity and T2 contrast. The utilization of such gradient thin films as molecular probes could enhance clinical MRI for in vitro diagnosis. This study indicated that thin-film gradients can offer a facile technique for unique cellular imaging via a lab-on-chip device to enable effective point-of-care molecular diagnostics.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2025 ","pages":"6630827"},"PeriodicalIF":4.5,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12558693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145389085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formulation and Optimization of Sustained-Release Diclofenac Microspheres for Orally Disintegrating Tablets.","authors":"Meron Amdework, Fantahun Molla, Afewerk Getachew","doi":"10.1155/ijbm/5552692","DOIUrl":"10.1155/ijbm/5552692","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic musculoskeletal problems necessitate long-term symptomatic treatments. In such cases, diclofenac (D_fNa) is frequently prescribed. However, its demand for frequent administration might result in serious dose-dependent complications. Furthermore, most patients with these illnesses are elderly and may have difficulty swallowing. Such factors can contribute to patients' noncompliance. Therefore, this study aimed to develop a sustained-release orally disintegrating D_fNa tablet using locally accessible excipients.</p><p><strong>Methods: </strong>D_fNa microspheres were prepared using the emulsion solvent evaporation technique. Several parameters, including drug-to-polymer ratio (DPR), stirring speed (SS), internal phase volume, and polyethylene glycol content, were explored for their effect on microsphere characteristics. Significant factors were then selected and further optimized to produce microspheres with desirable responses. Eventually, the optimized microspheres were compressed into orally disintegrating tablets with appropriate excipients through direct compression.</p><p><strong>Results: </strong>Preliminary studies indicated that the DPR and SS significantly influenced the response variables. Consequently, their effects on the selected response variables (entrapment efficiency [EE] and Z) were further optimized. This optimization identified optimal conditions at a DPR of 1:1.41 and SS of 905.17 rpm with a predicted EE (69.44%) and Z (175.33 μm). Confirmation tests indicated that the experimental results are in agreement with the predicted values (a percentage error below 5%). Furthermore, the three confirmation batches showed no significant difference in their characteristics, indicating remarkable reproducibility. The microspheres exhibited a non-Fickian anomalous release mechanism, best described by the Higuchi model. All the orally disintegrating tablets prepared from the microspheres met the USP specifications. However, FT1 (compressed at 10 KN) showed a release profile and kinetics similar to those of the uncompressed microspheres. Therefore, it was selected as the best formulation of D_fNa in this study.</p><p><strong>Conclusion: </strong>This study successfully formulated microsphere-based sustained-release orally disintegrating D_fNa tablets that sustained drug release for at least 12 h.</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2025 ","pages":"5552692"},"PeriodicalIF":4.5,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12543618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145354537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Comparative Release of Platelet-Derived Growth Factor-AA and Evaluation of Osteoblastic Proliferation of Two Liquid Platelet-Rich Fibrin Formulations (C-PRF and I-PRF): An In Vitro Study\".","authors":"","doi":"10.1155/ijbm/9852454","DOIUrl":"https://doi.org/10.1155/ijbm/9852454","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/ijbm/3568968.].</p>","PeriodicalId":13704,"journal":{"name":"International Journal of Biomaterials","volume":"2025 ","pages":"9852454"},"PeriodicalIF":4.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}