East European Journal of Parkinson`s Disease and Movement Disorders最新文献

{"title":"DIABETIC POLYNEUROPATHY AND COMORBIDITY ARE DIABETIC FOOT SYNDROME FORMATION FACTORS","authors":"V.M. Dubуnetska","doi":"10.33444/2414-0007.9.2.14-18","DOIUrl":"https://doi.org/10.33444/2414-0007.9.2.14-18","url":null,"abstract":"Background. Data from the literature indicate about the development of diabetic polyneuropathy in 5 years after the onset of type 1 diabetes and in 10-15% of patients with newly diagnosed type 2 diabetes. \u0000The purpose of the study was to find out the clinical course of diabetic polyneuropathy and to determine the frequency of the occurrence of diabetic foot syndrome in conditions of the comorbidity. \u0000Methods. We examined 121 patients, aged from 19 to 69 years, diagnosed with diabetic polyneuropathy due to type 1 and type 2 diabetes. The examined patients were divided into three groups: with diabetic polyneuropathy and cardiovascular comorbidity (group A, n=52), multimorbidity (more than 3 nosologies) (group B, n=30), without comorbidity (group C, n=39). \u0000Conclusions. Clinical manifestations of the diabetic polyneuropathy were more significant in the individuals with the cardiovascular comorbidity. The presence of stenoses and occlusions in the arterial channel in groups A and B served as a basis for the formation of ulcerative defects of the limbs in the future.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"16 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140240765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ORTHOSTATIC HYPOTENSION AND FRAILTY SYNDROM","authors":"A. Ovchynnykova, Y. Trufanov, N. Svyrydova","doi":"10.33444/2414-0007.9.2.8-13","DOIUrl":"https://doi.org/10.33444/2414-0007.9.2.8-13","url":null,"abstract":"The objective of our research was to define the relationship between orthostatic hypotension (OH) and frailty syndrome (FS) in the older age group. \u0000Materials and methods: the cross-sectional study involved patients of the older age group diagnosed with Parkinson's disease (PD) and cerebrovascular disease (CVD - chronic cerebral ischemia, chronic phase of ischemic stroke). All patients had comorbid OH. OH was established on the basis of a classical orthostatic test [10]. Each group included patients with different functional classes of OH (FC OH), from 1 to 4 [7]. The functional class of OH was determined using the orthostatic hypotension questionnaire (assessment of OH symptoms and the OH daily activity scale) [8]. All participants were assessed for the FS index based on the Edmonton Frail Scale [9]. \u0000Results: OH and FS has a close relationship, which is reflected in the direct correlation between OH and FS index (r=0.9). The higher FC OH, the more severe FS (p=0.001). The FC OH 1 corresponds to vulnerable, FC OH 2 to mild FS, FC OH 3 to moderate FS, and FC OH 4 to severe FS. \u0000Conclusions: OH, having a close relationship with FS, may make an additional contribution to the reduction of the duration and quality of life of patients with FS and elderly patients [3, 5]. Unfortunately, currently, OH has not been included in the criteria of FS and is not evaluated in this cohort [9]. Therefore, we believe it is important to perform orthostatic testing in all patients with FS, which will prevent the occurrence of life-threatening complications caused by the persistence of OH [3, 5]. In the future, OH should be included in the criteria of FS.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":" 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140392206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ORGANIZATION OF CONTINUOUS PROFESSIONAL DEVELOPMENT IN REFLEXOLOGY","authors":"G. Chupryna, N. Svyrydova, Y. Trufanov, N.V. Hanenko","doi":"10.33444/2414-0007.9.2.3-7","DOIUrl":"https://doi.org/10.33444/2414-0007.9.2.3-7","url":null,"abstract":"The article analyzes the work experience of the Department of Neurology and Reflexology in organizing a continuous educational process in reflexology. The advantages of studying under the guidance of experienced teachers within the programs of specialization cycles organized by specialized departments have been demonstrated. For the purpose of continuous professional development, trainees are recommended to attend relevant cycles of thematic improvement, thematic schools, master classes, scientific and practical conferences.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"33 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DIABETIC POLYNEUROPATHY: FOCUS ON CLINIC AND DIAGNOSTICS","authors":"V.M. Dubуnetska","doi":"10.33444/2414-0007.8.1.15-18","DOIUrl":"https://doi.org/10.33444/2414-0007.8.1.15-18","url":null,"abstract":"The objective of our research was to describe various clinical manifestations of diabetic polyneuropathy, modern diagnostic methods to increase the level of awareness of neurologists, endocrinologists and general practitioners of family medicine. Materials and methods. Specialized medical literature, medical databases PubMed and Medscape were analyzed. Discussion. In the genesis of the acute sensory neuropathy take part sharply pronounced fluctuations of glycemia, in connection with which they can be united into a single pathogenetic whole. A rare lesion of the peripheral nervous system in diabetes is “Bruns-Garland syndrome”. In all patients at the stage of clinically asymptomatic neuropathy, on electroneuromyography are showed the signs of sensory axonal polyneuropathy, mainly of the lower extremities. Reduced heart rate variability is the earliest indicator of cardiac autonomic neuropathy.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132884851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ORTHOSTATIC HYPOTENSION AS A NON-MOTOR SYMPTOM OF PARKINSON’S DISEASE","authors":"A.S. Ovchynnykova, Y. Trufanov","doi":"10.33444/2414-0007.8.1.3-12","DOIUrl":"https://doi.org/10.33444/2414-0007.8.1.3-12","url":null,"abstract":"The objective of our research was to raise awareness of neurologists about orthostatic hypotension (OH) in Parkinson’s disease (PD) and to explore the current approach to the problem. Materials and methods. This work was performed by searching for current information on OH in PD, reflecting the pathophysiology, classification, symptoms, diagnosis, and treatment. PubMed and Google Scholar resources were used to write the review. Results. An important task in the management of patients with PD is diagnostic and treatment of OH due to the negative impact of the syndrome on somatic, psychological and cognitive status. According to recent data, the prevalence of OH among PD patients is 30-50% [1] with no association with the stage of the disease [2]. OH in PD is neurogenic (NOH); it results from neurodegenerative damage to the central and peripheral structures of the sympathetic nervous system, which leads to reduced postganglionic release of epinephrine [3]. It is often asymptomatic, as a result of compensatory tolerance mechanisms [1]. In about of 50% of patients [4], OH is associated with supine hypertension [2] and may have a connection with REM-sleep disorders [5]. Classification features of OH include: onset period under orthostatic stress, the relationship of OH to different parts of the cardiac cycle, mechanism of pathophysiology, clinical course, presence of symptoms and clinical severity [20, 31, 32]. OH symptoms usually occur during orthostatic stress. They include dizziness, blurred vision, cognitive slowing, syncope, coat-hanger pain, difficulty breathing, leg buckling or leg weakness, general weakness and fatigue [1, 5, 17, 18]. Bedside orthostatic test with blood pressure measurement at the 1st, 3rd and 5th minutes of standing and ambulatory blood pressure monitoring (ABPM) are used for diagnosis [6]. The treatment strategy is to evaluate the medications taken by the patient and obligatory inclusion of non-pharmacological treatment. Pharmacological treatment for supine hypertension and OH is only given if necessary [1, 2]. Conclusions. OH is a widespread non-motor symptom of PD [1], which should be timely diagnosed and treated because of the negative impact on quality of life with increased risk of death and injuries due to falls [31, 32, 33]. The relationship between OH and other non-motor symptoms of PD should be further explored, and optimal therapeutic strategies for different functional classes and a combination of non-pharmacological and pharmacological treatments for OH should be found as well.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"219 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130845295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EXTRACEREBELLAR SIGNS OF SPINOCEREBELLAR ATAXIA TYPE 5","authors":"Y. Trufanov","doi":"10.33444/2414-0007.8.1.13-14","DOIUrl":"https://doi.org/10.33444/2414-0007.8.1.13-14","url":null,"abstract":"Background: The vast majority of studies and reviews state that spinocerebellar ataxia type 5 (SCA5) is exclusively manifested by pure ataxia. We found scant information on extracerebellar manifestations of SCA5.\u0000Objective: The purpose of our review was to find any information about extracerebellar signs of spinocerebellar ataxia type 5.\u0000Methods: PubMed and Google Scholar resources were used to write the review article.\u0000Results: Ranum L.P., et al. (1994), and Bürk K., et al. (2004) described writer’s cramp dystonia, facial myokymia, limited lateral gaze, brisk reflexes, and impaired vibration sense in patients with SCA5 [1, 2]. \u0000Maschke M., et al. (2005) noticed the possible presence of hyperreflexia, incontinence, tingling and cramps, diplopia, horizontal and vertical ophthalmoparesis in patients with SCA5 [3].\u0000Spagnoli C., et al. (2020) documented infantile-onset SCA5 with optic atrophy and peripheral neuropathy, and bilateral cataracts as associated findings [4].\u0000Stevanin G., et al. (1999) had shown that facial myokymia and decreased vibration sense are frequent and reflect lesions of other structures than the cerebellum or its pathways [5].\u0000We did not find any article describing parkinsonism in patients with SCA5.\u0000Conclusion: Extracerebellar manifestations of SCA5 are rare, but at the same time they can occur and are described in the literature.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134394488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DISTRIBUTION OF TYPES OF PSYCHOLOGICAL RESPONSE TO THE DISEASE IN DIFFERENT GROUPS OF PATIENTS WITH CHRONIC PHASE OF ISCHEMIC STROKE","authors":"A. Babirad","doi":"10.33444/2414-0007.7.1-2.7-14","DOIUrl":"https://doi.org/10.33444/2414-0007.7.1-2.7-14","url":null,"abstract":"The objective of our research was to study the types of psychological response to the disease in different groups of patients with chronic phase of ischemic stroke.\u0000Material and methods. 100 consecutive patients with chronic phase of ischemic stroke and 17 patients with chronic cerebral ischemia were questioned in neurology in-patient department. The types of attitude towards disease were identified with the help of the Personal Questionnaire of the Bekhterev Institute.\u0000Results. Our data indicate that clinical (location of the ischemic lesion, severity of paresis), laboratory (cholesterol level) and individual (gender and education) factors are involved in the formation of the internal picture of the disease in patients with chronic phase of ischemic stroke.\u0000Keywords: ischemic stroke, the Personal Questionnaire of the Bekhterev Institute, attitudes towards disease.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123240391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ON THE VERGE OF THE PROFESSIONAL HALF-CENTURY WITH THE GLORY","authors":"O. Onoprienko","doi":"10.33444/2414-0007.7.1-2.15-18","DOIUrl":"https://doi.org/10.33444/2414-0007.7.1-2.15-18","url":null,"abstract":"The article tells about the history of the Anthem of Neurology, publishes words, notes and provides a link to the audio file (https://youtu.be/zVAVNAukUOA).\u0000The author of the words is Oleksiy Onoprienko. Composer is Volodymyr Ilemsky.\u0000The men’s choir of the G. Veryovka Ukrainian National Honored Academic Folk Choir sings.\u0000Keywords: neurology, Anthem of Neurology, The men’s choir of the G. Veryovka Ukrainian National Honored Academic Folk Choir sings.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133218681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLUTEN ATAXIA - A COMMON, COMMONLY MISDIAGNOSED DISEASE","authors":"Y. Trufanov, N. Svyrydova, M. Martynovsky","doi":"10.33444/2414-0007.7.1-2.3-7","DOIUrl":"https://doi.org/10.33444/2414-0007.7.1-2.3-7","url":null,"abstract":"The objective of our research was to raise awareness of neurologists and family physicians about gluten ataxia and improve the diagnostic approaches.\u0000Methods. PubMed and Google Scholar resources were used to write the review article.\u0000Discussion. It is incredibly important not to overlook treatable courses of ataxia. One of these diseases is gluten ataxia. Early diagnosis and timely treatment (gluten-free diet) of gluten ataxia leads to a significant improvement of clinical symptoms and prevents their progression. Gluten ataxia is one of the most common and commonly misdiagnosed ataxia. Its prevalence among all ataxias is 15% and reaches 40% among all idiopathic sporadic ataxias (Hadjivassiliou M., Sanders D.D., Aeschlimann D.P., 2015).\u0000Keywords: gluten ataxia, celiac disease, gluten-related disorders.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115576407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ATTITUDES TOWARDS DISEASE IN PATIENTS WITH CHRONIC PHASE OF ISCHEMIC STROKE BY THE RESULTS OF THE PERSONAL QUESTIONNAIRE OF THE BEKHTEREV INSTITUTE","authors":"A. Babirad","doi":"10.33444/2414-0007.6.3-4.19-26","DOIUrl":"https://doi.org/10.33444/2414-0007.6.3-4.19-26","url":null,"abstract":"Every year, strokes are diagnosed in about 16 million people, of whom 5.7 million die and about the same number become disabled (Feigin V.L., Forouzanfar M.H., Krishnamurthi R., et al., 2014; Virani S.S., Alonso A., Benjamin E.J., et al., 2020; Kim J., Thayabaranathan T., Donnan G.A., et al. 2020). The objective of our research was to study the attitudes towards disease in patients with chronic phase of ischemic stroke. Material and methods. 100 consecutive patients with chronic phase of ischemic stroke and 17 patients with chronic cerebral ischemia were questioned in neurology in-patient department. The types of attitude towards disease were identified with the help of the Personal Questionnaire of the Bekhterev Institute. Results. We found that pathological types of attitude towards disease begin to form before the development of a stroke as a result of chronic cerebral ischemia. Among patients with chronic phase of ischemic stroke, pathological types of attitude towards disease prevailed significantly, and the harmonious type was rare (84.0% vs 16.0%, p < 0.001). The most frequently observed were neurasthenic (36.0%), harmonious (16.0%), anxious (16.0%), ergopathic (10.0%) and sensitive (8.0%) types of attitude towards disease. Our study has shown that any ischemic stroke, even in the case of complete recovery of the lost functions, can be associated with pathological types of attitude towards disease. \u0000Keywords: ischemic stroke, the Personal Questionnaire of the Bekhterev Institute, attitudes towards disease.","PeriodicalId":135229,"journal":{"name":"East European Journal of Parkinson`s Disease and Movement Disorders","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121605546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}