DIABETIC POLYNEUROPATHY AND COMORBIDITY ARE DIABETIC FOOT SYNDROME FORMATION FACTORS

V.M. Dubуnetska
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Abstract

Background. Data from the literature indicate about the development of diabetic polyneuropathy in 5 years after the onset of type 1 diabetes and in 10-15% of patients with newly diagnosed type 2 diabetes. The purpose of the study was to find out the clinical course of diabetic polyneuropathy and to determine the frequency of the occurrence of diabetic foot syndrome in conditions of the comorbidity. Methods. We examined 121 patients, aged from 19 to 69 years, diagnosed with diabetic polyneuropathy due to type 1 and type 2 diabetes. The examined patients were divided into three groups: with diabetic polyneuropathy and cardiovascular comorbidity (group A, n=52), multimorbidity (more than 3 nosologies) (group B, n=30), without comorbidity (group C, n=39). Conclusions. Clinical manifestations of the diabetic polyneuropathy were more significant in the individuals with the cardiovascular comorbidity. The presence of stenoses and occlusions in the arterial channel in groups A and B served as a basis for the formation of ulcerative defects of the limbs in the future.
糖尿病多发性神经病变和合并症是糖尿病足综合征的形成因素
背景。文献数据显示,1 型糖尿病患者在发病 5 年后会出现糖尿病多发性神经病变,新确诊的 2 型糖尿病患者中有 10%-15%会出现糖尿病多发性神经病变。本研究旨在了解糖尿病多发性神经病变的临床过程,并确定在合并症的情况下糖尿病足综合征的发生频率。研究方法我们对 121 名因 1 型和 2 型糖尿病而被诊断为糖尿病多发性神经病变的患者进行了研究,他们的年龄在 19 岁至 69 岁之间。受检患者分为三组:合并糖尿病多发性神经病变和心血管疾病(A 组,52 人)、多病(3 种以上病名)(B 组,30 人)、无合并症(C 组,39 人)。结论糖尿病多发性神经病变的临床表现在合并心血管疾病的患者中更为明显。A 组和 B 组的动脉通道存在狭窄和闭塞,为日后肢体溃疡性缺损的形成奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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