DIABETIC POLYNEUROPATHY AND COMORBIDITY ARE DIABETIC FOOT SYNDROME FORMATION FACTORS

Background. Data from the literature indicate about the development of diabetic polyneuropathy in 5 years after the onset of type 1 diabetes and in 10-15% of patients with newly diagnosed type 2 diabetes. The purpose of the study was to find out the clinical course of diabetic polyneuropathy and to determine the frequency of the occurrence of diabetic foot syndrome in conditions of the comorbidity. Methods. We examined 121 patients, aged from 19 to 69 years, diagnosed with diabetic polyneuropathy due to type 1 and type 2 diabetes. The examined patients were divided into three groups: with diabetic polyneuropathy and cardiovascular comorbidity (group A, n=52), multimorbidity (more than 3 nosologies) (group B, n=30), without comorbidity (group C, n=39). Conclusions. Clinical manifestations of the diabetic polyneuropathy were more significant in the individuals with the cardiovascular comorbidity. The presence of stenoses and occlusions in the arterial channel in groups A and B served as a basis for the formation of ulcerative defects of the limbs in the future.