IEEE transactions on ultrasonics, ferroelectrics, and frequency control最新文献_第8页

Unsupervised Test-Time Adaptation for Hepatic Steatosis Grading Using Ultrasound B-Mode Images 无监督测试时间适应肝脂肪变性分级使用超声b型图像。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-26 DOI: 10.1109/TUFFC.2025.3555180

Pedro Vianna;Paria Mehrbod;Muawiz Chaudhary;Michael Eickenberg;Guy Wolf;Eugene Belilovsky;An Tang;Guy Cloutier

{"title":"Unsupervised Test-Time Adaptation for Hepatic Steatosis Grading Using Ultrasound B-Mode Images","authors":"Pedro Vianna;Paria Mehrbod;Muawiz Chaudhary;Michael Eickenberg;Guy Wolf;Eugene Belilovsky;An Tang;Guy Cloutier","doi":"10.1109/TUFFC.2025.3555180","DOIUrl":"10.1109/TUFFC.2025.3555180","url":null,"abstract":"Ultrasound (US) is considered a key modality for the clinical assessment of hepatic steatosis (i.e., fatty liver) due to its noninvasiveness and availability. Deep learning methods have attracted considerable interest in this field, as they are capable of learning patterns in a collection of images and achieve clinically comparable levels of accuracy in steatosis grading. However, variations in patient populations, acquisition protocols, equipment, and operator expertise across clinical sites can introduce domain shifts that reduce model performance when applied outside the original training setting. In response, unsupervised domain adaptation techniques are being investigated to address these shifts, allowing models to generalize more effectively across diverse clinical environments. In this work, we propose a test-time batch normalization (TTN) technique designed to handle domain shift, especially for changes in label distribution, by adapting selected features of batch normalization (BatchNorm) layers in a trained convolutional neural network model. This approach operates in an unsupervised manner, allowing robust adaptation to new distributions without access to label data. The method was evaluated on two abdominal US datasets collected at different institutions, assessing its capability in mitigating domain shift for hepatic steatosis classification. The proposed method reduced the mean absolute error in steatosis grading by 37% and improved the area under the receiver operating characteristic curves (AUC) for steatosis detection from 0.78 to 0.97, compared to nonadapted models. These findings demonstrate the potential of the proposed method to address domain shift in US-based hepatic steatosis diagnosis, minimizing risks associated with deploying trained models in various clinical settings.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"601-611"},"PeriodicalIF":3.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BentRay-NeRF: Bent-Ray Neural Radiance Fields for Robust Speed-of-Sound Imaging in Ultrasound Computed Tomography BentRay-NeRF：用于超声计算机断层扫描中稳健声速成像的弯曲射线神经辐射场。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-26 DOI: 10.1109/TUFFC.2025.3554223

Shilong Cui;Qing Wu;Yiming Huang;Haizhao Dai;Yuyao Zhang;Jingyi Yu;Xiran Cai

{"title":"BentRay-NeRF: Bent-Ray Neural Radiance Fields for Robust Speed-of-Sound Imaging in Ultrasound Computed Tomography","authors":"Shilong Cui;Qing Wu;Yiming Huang;Haizhao Dai;Yuyao Zhang;Jingyi Yu;Xiran Cai","doi":"10.1109/TUFFC.2025.3554223","DOIUrl":"10.1109/TUFFC.2025.3554223","url":null,"abstract":"Ultrasound computed tomography (USCT) is a promising technique for breast cancer detection because of its quantitative imaging capability of the speed of sound (SOS) of soft tissues and the fact that malignant breast lesions often have a higher SOS compared to healthy tissues in the human breast. Compared to waveform inversion-based USCT, bent-ray tracing USCT is relatively less computationally expensive, which particularly suits breast cancer screening in a large population. However, SOS image reconstruction using bent-ray tracing in USCT is a highly ill-conditioned problem, making it susceptible to measurement errors. This presents significant challenges in achieving stable and high-quality reconstructions. In this study, we show that using implicit neural representation (INR), the ill-conditioned problem can be well mitigated, and stable reconstruction is achievable. This INR approach uses a multilayer perceptron (MLP) with hash encoding to model the slowness map as a continuous function, to better regularize the inverse problem and has been shown more effective than classical approaches of solely adding regularization terms in the loss function. Thereby, we propose the bent-ray neural radiance fields (BentRay-NeRF) method for SOS image reconstruction to address the aforementioned challenges in classical SOS image reconstruction methods, such as the Gauss-Newton method. In silico and in vitro experiments showed that BentRay-NeRF has remarkably improved performance compared to the classical method in many aspects, including the image quality and the robustness of the inversion to different acquisition settings in the presence of measurement errors.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"612-623"},"PeriodicalIF":3.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extended Field of View Imaging Through Correlation With an Experimental Database 通过与实验数据库的关联扩展视场成像。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-25 DOI: 10.1109/TUFFC.2025.3553784

Tamara Krpic;Maxime Bilodeau;Meaghan A. O’Reilly;Patrice Masson;Nicolas Quaegebeur

{"title":"Extended Field of View Imaging Through Correlation With an Experimental Database","authors":"Tamara Krpic;Maxime Bilodeau;Meaghan A. O’Reilly;Patrice Masson;Nicolas Quaegebeur","doi":"10.1109/TUFFC.2025.3553784","DOIUrl":"10.1109/TUFFC.2025.3553784","url":null,"abstract":"In this article, a correlation-based (CB) ultrasound imaging technique is implemented to extend the field of view (FOV) in the inspected medium and to enhance image homogeneity. This implementation involves the acquisition, the compression, and the adaptation of a database of experimental reference signals (CB-Exp), consisting of backpropagated reflections on point-like scatterers at different positions, as an improvement over preceding implementations involving a database of numerical reference signals (CB-Num). Starting from a large database acquired in water to a database with a 99% size reduction that can be applied to tissue-like media, CB-Exp has been validated in vitro on a CIRS 040GSE phantom. When compared with the synthetic aperture focusing technique (SAFT) and CB-Num, CB-Exp results show reduced sensitivity to the probe’s directivity, allowing an FOV extension from 25° with SAFT to 75° with CB-Exp. In vivo testing on a piglet’s heart with CB-Exp imaging showed a 3.5-dB contrast improvement on the pericardium wall. Overall benefits of this method include a reduction in the background gCNR standard deviation (std) of 0.2 and a reduction in the std of 10 dB in the point-like targets levels, which translates to more homogeneous sensitivity in the axial and lateral directions of the image.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"646-655"},"PeriodicalIF":3.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solidly Mounted Scandium Aluminum Nitride on Acoustic Bragg Reflector Platforms at 14–20 GHz 14-20 GHz声学Bragg反射平台固载氮化钪铝。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-25 DOI: 10.1109/TUFFC.2025.3554597

Ian Anderson;Omar Barrera;Nishanth Ravi;Lezli Matto;Kapil Saha;Supratik Dasgupta;Joshua Campbell;Jack Kramer;Eugene Kwon;Tzu-Hsuan Hsu;Sinwoo Cho;Pietro Simeoni;Jue Hou;Matteo Rinaldi;Mark S. Goorsky;Ruochen Lu

{"title":"Solidly Mounted Scandium Aluminum Nitride on Acoustic Bragg Reflector Platforms at 14–20 GHz","authors":"Ian Anderson;Omar Barrera;Nishanth Ravi;Lezli Matto;Kapil Saha;Supratik Dasgupta;Joshua Campbell;Jack Kramer;Eugene Kwon;Tzu-Hsuan Hsu;Sinwoo Cho;Pietro Simeoni;Jue Hou;Matteo Rinaldi;Mark S. Goorsky;Ruochen Lu","doi":"10.1109/TUFFC.2025.3554597","DOIUrl":"10.1109/TUFFC.2025.3554597","url":null,"abstract":"This article reports the first groups of low-loss acoustic solidly mounted resonators (SMRs) and acoustic delay lines (ADLs) at 14–20 GHz. Bulk acoustic waves (BAWs) are confined in thin-film scandium aluminum nitride (ScAlN) on top of dielectric acoustic Bragg reflectors, consisting of alternating silicon dioxide with tantalum pentoxide (Ta2O5/SiO<inline-formula> <tex-math>${}_{{2}}text {)}$ </tex-math></inline-formula> or niobium pentoxide (Nb2O5/SiO<inline-formula> <tex-math>${}_{{2}}$ </tex-math></inline-formula>) on Si carrier wafers. Stack material parameters are extracted via high-resolution X-ray diffraction (HRXRD) and X-ray reflectivity (XRR). The simulation and experiment show confinement for longitudinal BAW from 14 to 20 GHz. ADLs show high propagation Q above 478 and 171 for Ta2O5/SiO2 and Nb2O5/SiO2, respectively. SMRs in both stacks perform similarly, showing coupling coefficient (<inline-formula> <tex-math>${k}^{{2}}text {)}$ </tex-math></inline-formula> of 2.0%, series Q (<inline-formula> <tex-math>${Q}_{s}text {)}$ </tex-math></inline-formula> of 156, and parallel Q (<inline-formula> <tex-math>${Q}_{p}text {)}$ </tex-math></inline-formula> values of 140 for Ta2O5/SiO2, while <inline-formula> <tex-math>${k}^{{2}}$ </tex-math></inline-formula> of 2.4%, <inline-formula> <tex-math>${Q}_{s}$ </tex-math></inline-formula> of 140, and <inline-formula> <tex-math>${Q}_{p}$ </tex-math></inline-formula> of 109 for Nb2O5/SiO2, both at 18.6 GHz. Upon development, ScAlN solidly mounted platforms will enable signal processing elements with better power handling.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"656-662"},"PeriodicalIF":3.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scale Interdigital Transducer-Based Microacoustic Resonators Into mmWave Applications 基于数字间换能器的微声谐振器在毫米波中的应用。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-24 DOI: 10.1109/TUFFC.2025.3554004

Xingyu Liu;Junyan Zheng;Yansong Yang

{"title":"Scale Interdigital Transducer-Based Microacoustic Resonators Into mmWave Applications","authors":"Xingyu Liu;Junyan Zheng;Yansong Yang","doi":"10.1109/TUFFC.2025.3554004","DOIUrl":"10.1109/TUFFC.2025.3554004","url":null,"abstract":"Different orders of Lamb wave mode resonators using interdigital transducers (IDTs) and LiNbO3 thin films are increasingly important due to their large electromechanical coupling (<inline-formula> <tex-math>${k}_{text {t}}^{{2}}$ </tex-math></inline-formula>) and high phase velocities, essential for millimeter wave (mmWave) miniaturized acoustic filters. In <inline-formula> <tex-math>$50~Omega $ </tex-math></inline-formula> systems, achieving proper impedance matching necessitates large static capacitance. However, this capacitance may interact with self-inductance, leading to multiple electromagnetic (EM) self-resonances in the targeted spectrum, which is one of the major bottlenecks in using acoustic waves for mmWave applications. These resonances will decrease the series quality factor (Q) and alter the capacitive characteristics of the resonator, which significantly degrades the performance in filtering and frequency reference, especially with higher-order Lamb wave modes. Unlike the sub-6 GHz system, a new modeling method is needed to analyze the previously neglected EM-acoustic coupling in the 5 G/6G mmWave spectrum. This study proposes new design philosophies for IDTs to reduce self-inductance for mmWave applications, exploring the interactions between acoustic and EM waves within the IDTs and introducing new equivalent circuit models for various scenarios. To verify these methods, devices were fabricated on Y-128° cut LiNbO3 thin films. Both simulation and experimental results demonstrate the accuracy and efficiency of the proposed approaches. This work enables the effective use of IDT in the mmWave range without sacrificing necessary static capacitance and explains the EM effects based on the proposed multiphysic equivalent circuit models.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"674-685"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational Super-Resolution for Ultrasound Localization Microscopy Through Solving an Inverse Problem 求解逆问题的超声定位显微镜计算超分辨率。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-21 DOI: 10.1109/TUFFC.2025.3553735

Vassili Pustovalov;Duong Hung Pham;Corentin Alix;Jean-Pierre Remeniéras;Denis Kouamé

{"title":"Computational Super-Resolution for Ultrasound Localization Microscopy Through Solving an Inverse Problem","authors":"Vassili Pustovalov;Duong Hung Pham;Corentin Alix;Jean-Pierre Remeniéras;Denis Kouamé","doi":"10.1109/TUFFC.2025.3553735","DOIUrl":"10.1109/TUFFC.2025.3553735","url":null,"abstract":"Ultrasound localization microscopy (ULM) represents a significant advancement over traditional ultrasound (US) imaging, enabling super-resolution (SR) imaging of microvascular structures with unprecedented detail, by using microbubbles (MBs) as highly reflective contrast agents. After injection into the bloodstream, MBs are localized in US images to reconstruct the microvasculature. However, this technique faces a tradeoff between MB localization accuracy and acquisition time. Perfusion with low MB concentrations reduces signal overlap and achieves high localization accuracy but requires extended acquisition times. Conversely, higher MB concentrations shorten acquisition times but increase signal overlap, limiting localization precision. Traditionally, ULM consists of five main steps: tissue filtering, MB detection, MB super-localization, tracking, and rendering. In this study, we present a novel approach that combines a robust principal component analysis (RPCA) with a computational SR technique, replacing the first three steps of ULM with a single process based on solving an SR inverse problem. This method isolates MB signals from background noise and enhances the localization of overlapping MBs, thereby improving overall ULM performance. The experimental results from simulated and in vivo data demonstrate that our proposed approach increases the SR factor by up to 30% and enhances the contrast ratio (CR) by 3.5 dB. It also produces comparable results across other image quality metrics. These improvements enable denser, higher contrast vascular images.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"636-645"},"PeriodicalIF":3.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MRI Coregistered Rodent Histotripsy Array for Orthotopic Liver Models 用于原位肝脏模型的核磁共振成像共聚焦啮齿动物组织切片阵列

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-20 DOI: 10.1109/TUFFC.2025.3553083

Ryan Hubbard;David Choi;Tejaswi Worlikar;Ulrich Scheven;Hanna Kim;Jonathan R. Sukovich;Timothy L. Hall;Zhen Xu

{"title":"MRI Coregistered Rodent Histotripsy Array for Orthotopic Liver Models","authors":"Ryan Hubbard;David Choi;Tejaswi Worlikar;Ulrich Scheven;Hanna Kim;Jonathan R. Sukovich;Timothy L. Hall;Zhen Xu","doi":"10.1109/TUFFC.2025.3553083","DOIUrl":"10.1109/TUFFC.2025.3553083","url":null,"abstract":"Histotripsy has emerged as a promising therapeutic option for liver tumors, recently gaining food and drug administration (FDA) approval for clinical use in October 2023. Preclinical in vivo histotripsy experiments primarily utilize subcutaneous ectopic murine tumor models, which fail to accurately replicate the complex immunosuppressive tumor microenvironment (TME) of liver tumors. In order to address this gap, we present the design, development, and in vivo demonstration of a miniature, electronically steerable magnetic resonance imaging (MRI)-guided histotripsy array tailored for orthotopic murine liver tumor models. This novel system integrates an 89-element phased array within a 7.0-T small animal MRI scanner, enabling precise targeting through enhanced soft tissue contrast and 3-D visualization. The targeting accuracy of the array was validated in tissue-mimicking red blood cell (RBC) phantoms, exhibiting targeting precision of <inline-formula> <tex-math>$0.24~pm ~0.1$ </tex-math></inline-formula> mm. Subsequent in vivo experiments in naïve mice demonstrated successful liver ablations, confirmed by gross morphology and histological analysis. However, the presence of grating lobes led to undesired collateral damage, highlighted by lung hemorrhages, necessitating future adjustments in the array’s design. This study illustrates the foundational steps necessary for translating histotripsy experiments from subcutaneous to orthotopic models.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 5","pages":"581-590"},"PeriodicalIF":3.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single Probe Enabled Refraction-Corrected Transcranial Passive Acoustic Mapping Through Macaque Calvaria 猕猴颅部单探头折射校正经颅被动声学定位。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-19 DOI: 10.1109/TUFFC.2025.3570971

Gaofei Jin;Yi Zeng;Hui Zhu;Guotao Quan;Xiran Cai;Dean Ta

{"title":"Single Probe Enabled Refraction-Corrected Transcranial Passive Acoustic Mapping Through Macaque Calvaria","authors":"Gaofei Jin;Yi Zeng;Hui Zhu;Guotao Quan;Xiran Cai;Dean Ta","doi":"10.1109/TUFFC.2025.3570971","DOIUrl":"10.1109/TUFFC.2025.3570971","url":null,"abstract":"In microbubble (MB) cavitation-mediated blood-brain barrier (BBB) opening, prior knowledge of the skull’s sound speed properties is required to correct phase aberration and achieve accurate localization of the cavitation source using transcranial passive acoustic mapping (TPAM). Current approaches predominantly rely on CT scans to generate an empirically sound speed map (SSM) for correction after registering the two imaging modalities. This increases hardware complexity and cost while introducing additional errors from the registration process and the empirical sound speed values in the SSM. Here, we propose an all-ultrasound (US), single-probe method for refraction-corrected TPAM. This method first deploys the head wave technique to reconstruct an approximate multilayer SSM of the skull. This SSM is then combined with the heterogeneous angular spectrum approach (ASA) for PAM to efficiently reconstruct refraction-corrected TPAM images. In the in vitro hydrophone and MB cavitation experiments using two whole macaque calvariae, we showed that the source localization error could be reduced to a submillimeter scale with the proposed method in the area where the F-number is less than 1.2. Compared to the cases without phase aberration correction, the localization error was reduced by about 1.8–5.9 times in the corrected cases, clearly demonstrating the effectiveness of the proposed method for transcranial acoustic source localization. We also showed that the proposed method achieved comparable performance on correcting source localization to the CT-corrected method. These preliminary results suggest that our method represents a low-cost solution for monitoring transcranial MB cavitation activity, particularly in the cortical regions, which could facilitate the investigation of MB-mediated focused therapies in the brain and warrants further study for clinical translation.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 7","pages":"920-931"},"PeriodicalIF":3.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control Publication Information IEEE超音波学、铁电学与频率控制论文集

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-17 DOI: 10.1109/TUFFC.2025.3549670

引用次数: 0

Assessing Ultrasound Safety: A Method for Correlating Stimulus Parameters With MI and TI 超声安全性评估：一种将刺激参数与心肌梗死和心肌梗死相关联的方法。

IF 3 2区工程技术

IEEE transactions on ultrasonics, ferroelectrics, and frequency control Pub Date : 2025-03-16 DOI: 10.1109/TUFFC.2025.3570878

Benedikt George;Stefan J. Rupitsch

{"title":"Assessing Ultrasound Safety: A Method for Correlating Stimulus Parameters With MI and TI","authors":"Benedikt George;Stefan J. Rupitsch","doi":"10.1109/TUFFC.2025.3570878","DOIUrl":"10.1109/TUFFC.2025.3570878","url":null,"abstract":"Diagnostic ultrasound safety indices, such as the mechanical index (MI) and the thermal index (TI), serve as approved risk estimators of bioeffects that can result from an ultrasound stimulus. However, especially in ultrasound-based indirect therapeutic applications, only the MI is reported while the TI is overlooked, possibly due to its complex calculation. To simplify the calculation, we present an analytical-numerical method for computing the TI, restricted to the −6-dB region of the ultrasound beam, based on equations provided by the International Electrotechnical Commission (IEC) standards. Central to this calculation is the assumption of a linearly propagating ultrasound wave with minimal nonlinear distortion. This assumption was verified by COMSOL simulations and hydrophone measurements in a two-layer setup consisting of water and a tissue-mimicking phantom (TMP) for a single-element, spherically focusing transducer with a central opening driven at a frequency of 950 kHz. For this configuration, the peak-rarefactional pressure (PRP) was evaluated up to 1.5 MPa. To facilitate the immediate assessment of ultrasound safety, MI and TI were mapped into characteristic diagrams, correlating them with pulse durations (PDs) between 0.1 and 3.5 ms at a pulse repetition period (PRPP) of 0.1 s and PDs between 0.01 and 0.35 ms at a PRPP of 0.01 s. These diagrams serve as a practical tool for determining whether an ultrasound stimulus adheres to diagnostic safety limits for MI and TI.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 7","pages":"932-944"},"PeriodicalIF":3.0,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0