Yihang Lian;Yi Zeng;Suian Zhou;Hui Zhu;Fei Li;Xiran Cai
{"title":"Deep Beamforming for Real-Time 3-D Passive Acoustic Mapping With Row-Column-Addressed Arrays","authors":"Yihang Lian;Yi Zeng;Suian Zhou;Hui Zhu;Fei Li;Xiran Cai","doi":"10.1109/TUFFC.2024.3524436","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3524436","url":null,"abstract":"Passive acoustic mapping (PAM) is a promising tool to monitor acoustic cavitation activities for focused ultrasound (FUS) therapies. While 2-D matrix arrays allow 3-D PAM, the high channel count requirement and the complexity of the receiving electronics limit their practical value in real-time imaging applications. In this regard, row-column-addressed (RCA) arrays have shown great potential in addressing the difficulties in real-time 3-D ultrasound imaging. However, currently, there is no applicable method for 3-D PAM with RCA arrays. In this work, we propose a deep beamformer for real-time 3-D PAM with RCA arrays. The deep beamformer leverages a deep neural network (DNN) to map radio frequency (RF) microbubble (MB) cavitation signals acquired with the RCA array to 3-D PAM images, achieving similar image quality to the reconstructions performed using the fully populated 2-D matrix array with the angular spectrum (AS) method. In the simulation, the images reconstructed by the deep beamformer showed less than 13.2% and 1.8% differences in the energy spread volume (ESV) and image signal-to-noise ratio (ISNR), compared with those reconstructed using the matrix array. However, the image reconstruction time was reduced by 11 and 30 times on the CPU and GPU, respectively, achieving 42.4 volumes per second image reconstruction speed on a GPU for a volume sized <inline-formula> <tex-math>$128times 128times 128$ </tex-math></inline-formula>. Experimental data further validated the capabilities of the deep beamformer to accurately localize MB cavitation activities in 3-D space. These results clearly demonstrated the feasibility of real-time and 3-D monitoring of MB cavitation activities with RCA arrays and neural network-based beamformers.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"226-237"},"PeriodicalIF":3.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniek A. C. van Aarle;Floor Fasen;Harold A. W. Schmeitz;Frederik J. de Bruijn;Marc R. H. M. van Sambeek;Hans-Martin Schwab;Richard G. P. Lopata
{"title":"Numerical Simulation of Intravascular Ultrasound Images Based on Patient-Specific Computed Tomography","authors":"Daniek A. C. van Aarle;Floor Fasen;Harold A. W. Schmeitz;Frederik J. de Bruijn;Marc R. H. M. van Sambeek;Hans-Martin Schwab;Richard G. P. Lopata","doi":"10.1109/TUFFC.2024.3523037","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3523037","url":null,"abstract":"Intravascular ultrasound (IVUS) provides detailed imaging of the artery circumference. Over the past years, the interest in artificial intelligence (AI) for interpretation and automatic analysis of IVUS images has grown. Development of such algorithms typically requires considerable amounts of annotated data. However, manual annotation of IVUS data is time-consuming and expensive. An alternative solution would be the simulation of IVUS data, which yields images with all necessary ground-truth data available. Therefore, in this study, we present an IVUS simulator to simulate realistic IVUS data based on computed tomography (CT) images. The IVUS transducer is modeled accurately, which is reflected in the in vitro and in silico measurements of the point-spread function (PSF) and speckle size. The capability of simulating realistic IVUS images is showcased on an in vivo co-registered CT-IVUS dataset of two patients with an abdominal aortic aneurysm (AAA). Quantitative results, expressed in terms of the Jensen-Shannon divergence (JSD), speckle signal-to-noise ratio (sSNR), and contrast-to-noise ratio (CNR), reveal the high similarity between the in vivo and in silico IVUS images. The proposed simulator is promising for ultrasound data generation, enabling the generation of IVUS images with the desired ground truth.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"215-225"},"PeriodicalIF":3.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Saccher;Alessandro Stuart Savoia;Rob van Schaijk;Johan H. Klootwijk;Ronald Dekker
{"title":"Pre-Charged Collapse-Mode Capacitive Micromachined Ultrasonic Transducer (CMUT) Receivers for Efficient Power Transfer","authors":"Marta Saccher;Alessandro Stuart Savoia;Rob van Schaijk;Johan H. Klootwijk;Ronald Dekker","doi":"10.1109/TUFFC.2024.3523179","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3523179","url":null,"abstract":"Capacitive micromachined ultrasonic transducers (CMUTs) offer several advantages over standard lead zirconate titanate (PZT) transducers, particularly for implantable devices. To eliminate their typical need for an external bias voltage, we embedded a charge storage layer in the dielectric. The objective of this study was to evaluate the performance of plasma-enhanced chemical vapor deposition (PECVD) Si3N4 and atomic layer deposition (ALD) Al2O3 as materials for the charge storage layer and two different dielectric layer thicknesses, focusing on their application as receivers in a wireless power transfer link. Capacitance–voltage (CV) measurements revealed that Si3N4 has a higher charge storage capacity compared to Al2O3. Additionally, a thicker dielectric layer between the bottom electrode and the charge storage layer (Bdiel) improved both charge trapping and retention, as assessed in dynamic accelerated lifetime transmit (TX)-mode tests. We then analyzed the power conversion performance of the fabricated CMUTs through both simulations and experiments. We performed extensive modeling based on an equivalent circuit derived from electrical impedance measurements of the fabricated CMUTs. The model was used to predict the power conversion efficiency under various conditions, including the charging field strength, the operating frequency, and parasitic series resistance. Power transfer experiments at 1- and 2.4-MHz recorded efficiencies exceeding 80% with an optimally matched load and up to 54% with a purely resistive load. Results confirmed that, with optimal load matching, the efficiency of different CMUT variants is comparable, indicating that the optimal variant should be selected based on additional criteria, such as charge retention time.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"283-297"},"PeriodicalIF":3.0,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10816438","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wenxuan Li;Zilin Li;Yang Yang;Luyang Liu;Ruchuan Shi;Chengtao Luo;Tao Han
{"title":"Generalized Multiphysical Fields Coupled Model of SAW Resonators: From Methodology to Applications","authors":"Wenxuan Li;Zilin Li;Yang Yang;Luyang Liu;Ruchuan Shi;Chengtao Luo;Tao Han","doi":"10.1109/TUFFC.2024.3522109","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3522109","url":null,"abstract":"Multiphysics modeling is crucial in surface acoustic wave (SAW) resonators. Existing coupling methods primarily focus on the displacement and electrical potential originating from the piezoelectric effect. As SAW technology advances, novel interaction mechanisms introduce new challenges in multiphysics modeling. In order to address these complexities, simulations must incorporate additional physical fields, such as semiconducting, thermal, and other fields. This study presents a comprehensive methodology for multiphysics coupling in SAW resonators, categorizing the couplings into direct and indirect types based on whether they occur through constitutive relations or through initial and boundary conditions. For direct coupling, we extend the intrinsic piezoelectric effect to piezoelectric and semiconducting coupling via constitutive laws as an illustrative example. Specifically, we simulate the electromechanical (EM)-carrier coupling in a multilayered SAW resonator, providing insights into the parasitic surface conduction (PSC) effect. In contrast, indirect coupling involves physical fields with frequencies significantly lower than that of SAW. As a representative case, we analyze the bidirectional interaction between the thermal field and SAW, where the bias field is simplified into initial and boundary conditions. A thermoelastic model using the sequential algorithm is proposed to predict the temperature coefficient of frequency (TCF) and the self-heating effect in multilayered SAW structures. Simulation results demonstrate excellent agreement with experimental data. Based on these findings, we propose optimization strategies to enhance the performance of SAW resonators.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"263-274"},"PeriodicalIF":3.0,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke D. Doucette;Morton G. Greenslit;Mauricio Pereira da Cunha
{"title":"Nuclear Irradiation and Characterization of Langasite SAWR Sensors up to 800 ∘C","authors":"Luke D. Doucette;Morton G. Greenslit;Mauricio Pereira da Cunha","doi":"10.1109/TUFFC.2024.3520421","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3520421","url":null,"abstract":"For next-generation advanced nuclear reactors, there is a significant need for new sensor materials and sensor technologies that are capable of withstanding in-core high gamma radiation (e.g., >10 Gy/s), neutron flux levels [<inline-formula> <tex-math>$gt 10^{{12}}$ </tex-math></inline-formula> n/(cm<inline-formula> <tex-math>$^{{2}} cdot $ </tex-math></inline-formula>s)], and high operating temperatures (<inline-formula> <tex-math>$gt 700~^{circ }$ </tex-math></inline-formula>C). In this work, langasite (LGS)-based surface acoustic wave resonator (SAWR) sensor devices were designed, fabricated, and tested in a research grade test reactor and demonstrated the ability to quantify total neutron flux by monitoring the SAWR frequency responses calibrated against the reactor’s total neutron flux when exposed to reactor powers of 100, 300, and 461 kW [or 0.42, 1.3, and <inline-formula> <tex-math>$2.0times 10^{{12}}$ </tex-math></inline-formula> n/(cm<inline-formula> <tex-math>$^{{2}} cdot $ </tex-math></inline-formula>s)] at temperatures up to <inline-formula> <tex-math>$800~^{circ }$ </tex-math></inline-formula>C and at a maximum gamma dose rate of 21 Gy/s. The effects of gamma heating on SAWR sensor frequency responses were accounted for by using instrumented control of an in situ furnace, where the sensor devices were loaded during irradiation. The controlled furnace allowed for the SAWR devices to be kept at a fixed temperature when exposed to different reactor powers/neutron flux levels. Using this approach, the measured variations in sensor frequency responses were then primarily attributed to neutron flux induced material softening of the SAWR devices. For irradiation measurements acquired at <inline-formula> <tex-math>$800~^{circ }$ </tex-math></inline-formula>C, the LGS SAWR sensors produced linear shifts in frequency response as a function of reactor power at a rate of approximately 3 kHz/100 kW.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"169-177"},"PeriodicalIF":3.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lenin Chinchilla;Régine Guillermin;Emilie Franceschini;Alessandro Stuart Savoia
{"title":"Study of the Impact of Probe Steering Capability on the Performance of Off-Axis Measurements of Backscattered Signals","authors":"Lenin Chinchilla;Régine Guillermin;Emilie Franceschini;Alessandro Stuart Savoia","doi":"10.1109/TUFFC.2024.3519194","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3519194","url":null,"abstract":"In the field of quantitative ultrasound (QUS), several studies have been conducted to parameterize tissue anisotropy by measuring the angular dependence of the backscatter coefficient (BSC). Early foundational studies utilized a single-element transducer, and more recent ones used ultrasound linear array probes. However, probe features such as directivity and crosstalk can strongly affect both, the transmission of an ultrasound beam and the measurements of the backscattered signals, independent of the imaging strategy used, either the focused beam steering or the plane wave imaging (PWI). In this work, we present a comparative analysis between a capacitive micromachined ultrasonic transducer (CMUT) probe and a commercial piezoelectric probe, in which the BSC is measured using the focused beam steering imaging strategy on isotropic and anisotropic tissue-mimicking phantoms along different insonification angles. The results show how the limited steering capabilities of linear probes can affect the measurement of BSC, and, in general, the anisotropic QUS parameters, bringing into discussion their consideration in the development of experimental strategies for the assessment of tissue anisotropy.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"251-262"},"PeriodicalIF":3.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10807367","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qi Zeng;Shahed K. Mohammed;Tajwar Abrar Aleef;Mohammad Honarvar;Caitlin Schneider;Emily H. T. Pang;James Jago;Alnoor Ramji;Eric M. Yoshida;Robert Rohling;Septimiu E. Salcudean
{"title":"Validation of Volumetric Multifrequency Shear Wave Vibro-Elastography With Matrix Array Transducer for the In Vivo Liver","authors":"Qi Zeng;Shahed K. Mohammed;Tajwar Abrar Aleef;Mohammad Honarvar;Caitlin Schneider;Emily H. T. Pang;James Jago;Alnoor Ramji;Eric M. Yoshida;Robert Rohling;Septimiu E. Salcudean","doi":"10.1109/TUFFC.2024.3519192","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3519192","url":null,"abstract":"Three-dimensional shear wave absolute vibro-elastography (S-WAVE) is a steady-state, volumetric elastography imaging technique similar to magnetic resonance elastography (MRE), with the additional advantage of multifrequency imaging and a significantly shorter examination time. We present a novel ultrasound matrix array implementation of S-WAVE for high-volume refresh rate acquisition. This new imaging setup is equipped with real-time shear wave monitoring for an improved data collection workflow and image quality. The image processing and elasticity reconstruction pipeline is tailored for high body mass index (BMI) subjects. We characterized this system with tissue phantoms and a human study cohort composed of 7 healthy volunteers and 25 patients with nonalcoholic fatty liver disease. The validation results show that S-WAVE can maintain a high agreement with the liver tissue stiffness measurements obtained with both the 2-D and 3-D MRE techniques, with an average cross correlation >93% and an average <inline-formula> <tex-math>${R} ^{{2}} =0.87$ </tex-math></inline-formula>, which outperforms the conventional transient elasticity technique. Our findings show that the matrix array-based 3-D S-WAVE is a suitable volumetric elastography imaging solution for delivering a similar assessment of liver fibrosis as MRE in a more accessible, flexible, and cost-effective way.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"178-190"},"PeriodicalIF":3.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"4-D Vector Doppler Imaging Using Row-Column Addressed Array","authors":"Qiandong Sun;Yapeng Fu;Shaoyuan Yan;Kailiang Xu","doi":"10.1109/TUFFC.2024.3519179","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3519179","url":null,"abstract":"Large aperture 4-D blood flow Doppler imaging with high temporal resolution remains an important challenge. Different from the conventional matrix-array strategy, we proposed a 4-D ultrasound vector Doppler (4D-UVD) imaging method using a <inline-formula> <tex-math>$128+128$ </tex-math></inline-formula> row-column addressed (RCA) array and a 256-channel ultrasound platform. This method integrates ultrafast 2-D plane wave transmission sequence and least-squares multiangle Doppler velocity estimator. The accuracy of the proposed method was evaluated in both simulations and phantom experiments of parabolic flow. The simulated result shows that the root-mean-squared error (RMSE) of estimated velocity is less than 15%. In the phantom experiments, the relative mean bias <inline-formula> <tex-math>$overline {B}$ </tex-math></inline-formula> and the standard deviation (SD) <inline-formula> <tex-math>$overline {sigma }$ </tex-math></inline-formula> of the velocity profiles are less than 7.9% and 6.9%, respectively, suggesting a high estimated precision. Furthermore, in vivo feasibility of the approach was demonstrated in the human carotid artery. The blood flow velocity of the carotid artery was continuously measured over seven cardiac cycles at a 1-kHz volume rate. The fluctuations of the estimated mean and peak velocities were highly consistent with the pulse waves measured using a gating pulse sensor, yielding synchronization coefficients of 0.85 and 0.87, respectively. It is thus concluded that the proposed method can achieve a large aperture 4-D vector flow imaging with high temporal resolution using an RCA probe.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 2","pages":"202-214"},"PeriodicalIF":3.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Mougharbel;Jonathan Porée;Stephen A. Lee;Paul Xing;Alice Wu;Jean-Claude Tardif;Jean Provost
{"title":"A Unified Framework Combining Doppler-Based Motion Compensation, Harmonic Imaging, and Angular Coherence for High-Quality B-Mode in Ultrafast Echocardiography","authors":"Michael Mougharbel;Jonathan Porée;Stephen A. Lee;Paul Xing;Alice Wu;Jean-Claude Tardif;Jean Provost","doi":"10.1109/TUFFC.2024.3505060","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3505060","url":null,"abstract":"Various methods have been proposed to enhance image quality in ultrafast ultrasound. Coherent compounding can improve image quality using multiple steered diverging transmits when motion occurring between transmits is corrected. Harmonic imaging has been adapted for ultrafast imaging to reduce clutter. Coherence-based approaches have also been shown to increase contrast in clinical settings by enhancing signals from coherent echoes. Herein, we introduce a simple, unified framework that combines motion correction, harmonic imaging, and angular coherence, showing for the first time that their benefits can be combined in real time. To do so, harmonic imaging was achieved through pulse inversion (PI), phase delay between successive transmits was assessed to perform motion compensation (MoCo), and ensemble autocorrelation between transmits was used to generate a weight applied to the coherently compounded frames. Validation was conducted through in vitro testing on a spinning disk model and in vivo on four volunteers. In vitro results confirmed the unified framework capability to achieve high contrast in large-motion contexts up to 17 cm/s. In vivo testing highlighted proficiency in generating images of high quality during low and high tissue velocity phases of the cardiac cycle. Specifically, during ventricular filling, the unified framework increased the generalized contrast-to-noise ratio (gCNR) from 0.47 to 0.87 when compared against coherent compounding.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"72 1","pages":"141-152"},"PeriodicalIF":3.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143107102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel 2x2D Radial Basis Function-Based Interpolation for Short Acquisition Time and Relaxed Frame Rate Ultrasound Localization Microscopy","authors":"Sajjad Afrakhteh;Giulia Tuccio;Libertario Demi","doi":"10.1109/TUFFC.2024.3515218","DOIUrl":"https://doi.org/10.1109/TUFFC.2024.3515218","url":null,"abstract":"Ultrasound localization microscopy (ULM) has become a potent technique for microvascular imaging using ultrasound waves. However, one major challenge is the high frame rate and lengthy acquisition time needed to produce super-resolved (SR) images. To overcome this, our goal is to relax the frame rate and shorten this acquisition time while preserving SR image quality, thereby enhancing ULM’s clinical applicability. To this end, we propose two distinct strategies: first, we suggest acquiring the data at lower frame rate followed by applying the reconstruction technique to compensate the lost information due to low frame rate imaging. Second, to tackle the prolonged acquisition time, we propose compressing acquisition time by a compression ratio (CR), which can degrade SR image quality due to reduced temporal information. To mitigate this, we temporally upsample the in-phase-quadrature (IQ) data by a factor equal to the CR after compressed acquisition. In addition, we introduce a novel bidirectional (2x2D) interpolation (IP) using radial basis function (RBF)-based reconstruction to estimate unknown values in the 3D IQ data (x–z–t), thereby enhancing temporal resolution. The rationale behind using 2x2D IP is its ability to integrate spatiotemporal information from two orthogonal x–t and z–t planes, effectively addressing anisotropies and nonuniformities in microbubble motion. This 2x2D approach improves the reconstruction of microbubbles’ dynamics by interpolating along both the x- and z-directions. The method was tested on rat brain and rat kidney datasets recorded at 1 kHz, demonstrating relaxing the frame rate to 100 Hz (using the first strategy) and a reduction in acquisition time by a factor of 3 to 4 (using the second strategy) while maintaining SR image quality comparable to the original uncompressed data, including density and velocity maps.","PeriodicalId":13322,"journal":{"name":"IEEE transactions on ultrasonics, ferroelectrics, and frequency control","volume":"71 12: Breaking the Resolution Barrier in Ultrasound","pages":"1855-1867"},"PeriodicalIF":3.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10793238","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142938380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}