Indian Journal of Microbiology最新文献

{"title":"Impact of Climate Change on Zoonotic Diseases and Antimicrobial Resistance.","authors":"Shailendra Yadav, Shipra","doi":"10.1007/s12088-024-01430-3","DOIUrl":"https://doi.org/10.1007/s12088-024-01430-3","url":null,"abstract":"<p><p>Climate change along with infectious disease and antimicrobial resistance are imposing threat to public health globally. Climate change mediates frequent rise in antimicrobial resistance leading to the emergence of zoonotic vectors. Both climate change and AMR contribute significantly to global morbidity and mortality and impose burden on the healthcare sector. Overexploitation of antimicrobials in various sectors causes broader dissemination of AMR. Therefore, the application of a holistic \"One Health Approach\" is required to combat both climate change and antimicrobial resistance. Increasing public awareness about the negative consequences of climate change and antimicrobial resistance is essential. Also, the discovery of new antimicrobials has become the need of the present world. The application of metagenomics has the potential to shed light on microbial community dynamics (taxonomic abundance and predominant biochemical pathways) in response to climate change. The application of modern tools like functional metagenomics has the potential to yield new antimicrobial compounds for combating AMR.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12088-024-01430-3.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"280-291"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147971972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradation of Heavy Metals by Biosorption: A Comprehensive Tool for Environmental Remediation.","authors":"Vijayakumar Vaguldas, Rajashekhar Musani, Madhusudan Reddy Dadireddy","doi":"10.1007/s12088-025-01468-x","DOIUrl":"https://doi.org/10.1007/s12088-025-01468-x","url":null,"abstract":"<p><p>Heavy metal poisoning of soil and water sources poses a serious risk to the environment and people's health. Heavy metal removal using conventional techniques is frequently costly and inefficient. Microorganism-based bioremediation techniques have gained popularity recently since they are both economical and environmentally benign. <i>Streptomyces species</i> have been identified as attractive candidates for the biosorption of heavy metals because of their diverse metabolic capacities. These bacteria use a range of surface interactions for their biosorption mechanism, including ion exchange, complexation, precipitation, and physical adsorption. Chitin, glucans, and proteins make up <i>Streptomyces</i>' distinctive cell wall composition, which is essential for heavy metal binding. The article covers how <i>Streptomyces</i>-mediated biosorption may be used to treat contaminated soils, mining effluents, and industrial wastes. To fully utilize <i>Streptomyces</i> species' biosorption potential for environmental remediation, additional studies are required with an emphasis on optimizing biosorption conditions, comprehending the underlying mechanisms, and scale-up protocols. The biosorption is the prospective uses of <i>Streptomyces</i>-mediated biosorption for the cleanup of contaminated soils, mining effluents, and industrial wastes. The difficulties and prospects for using <i>Streptomyces</i> species in extensive heavy metal bioremediation are also discussed.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"374-380"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Donor Vector for Efficient CRISPR/Cas9-Mediated Homology-Directed Integration at the <i>CAN1</i> Locus in <i>Saccharomyces cerevisiae</i>.","authors":"Vo Thi Hoang Lan, La Ho Truc Lam, Chau Quoc Cuong, Luc Mai Thanh, Le Thi Kim Lien, Le Kha Han, Nguyen Hieu Nghia","doi":"10.1007/s12088-025-01457-0","DOIUrl":"https://doi.org/10.1007/s12088-025-01457-0","url":null,"abstract":"<p><p><i>Saccharomyces cerevisiae</i> is a widely utilized host organism for recombinant protein production due to its robustness, versatility, and ease of genetic manipulation. Gene integration into its genome is a critical strategy for achieving stable and efficient protein expression. However, incorporating large gene cassettes at specific loci, such as the <i>CAN1</i> locus, remains technically challenging. While CRISPR/Cas9-based genome editing has significantly improved precision, the efficiency of integrating large constructs can still be limited. In this study, we optimized a CRISPR/Cas9-based approach using the pBlueHA donor vector, which contains approximately 500 bp homology arms flanking the <i>CAN1</i> locus, to enhance gene integration efficiency. By testing 13 genes of interest (GOIs) of various sizes, up to 4756 bp in size, we successfully achieved integration into the yeast genome. Linearized GOIs ranging exhibited significantly higher integration efficiencies, ranging from 85.3 to 100%, compared to circular cassettes. These results highlight the importance of extended homology arms in improving integration efficiency, providing a robust platform for optimizing genome engineering in <i>S. cerevisiae</i> to enhance recombinant protein production and other biotechnological applications.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12088-025-01457-0.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"352-358"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Trichoderma</i>'s Metabolomic Journey: Unveiling Bioactive Secondary Metabolites for Sustainable Solutions for Agriculture and Beyond.","authors":"Jasleen Kaur, Dweipayan Goswami, Meenu Saraf","doi":"10.1007/s12088-025-01507-7","DOIUrl":"https://doi.org/10.1007/s12088-025-01507-7","url":null,"abstract":"<p><p>The <i>Trichoderma</i> genus, a prolific producer of bioactive secondary metabolites (SM) serves as a promising alternative to chemical treatments for biological disease control. Phytopathogenic fungi and pests significantly reduce global crop yields, with synthetic pesticides posing severe ecological risks; thus, sustainable alternatives like <i>Trichoderma</i> are gaining prominence for crop protection and growth enhancement. Additionally, <i>Trichoderma</i> SM, hold immense potential for drug development, offering promising solutions against multidrug-resistant pathogens in human, veterinary medicine and other biotechnological sectors. SMs could be discovered through biochemical (production and structure elucidation), molecular (for exploring natural product diversity at genomic level) as well as computational approaches (understanding Biosynthetic Gene Cluster). The biosynthesis of SMs is closely regulated by BGCs, with proteins like LaeA1, TOR1, and Tmk3 playing critical roles. Transcription factors such as THCTF1, THMTF1, and the Tag1 gene further modulate SM production, either positively or negatively.The synthesis of these metabolites is intricately linked to biosynthetic gene clusters, providing avenues for understanding and modulating their expression for potential applications.These SMs, spanning anthraquinones, simple pyrones, peptaibols, sesquiterpenes, alkaloids, and non-ribosomal peptides (NRPs), displaying multifaceted bioactivities such as antibacterial, anticancer, antioxidant, anti-inflammatory, antifungal, antimalarial, and nematocidal properties. Noteworthy, SMs like longibrachins, 6-pentyl-α-pyrone, butyrolactone produced by <i>Trichoderma</i>, demonstrate significant antibacterial, antifungal, antitumor, antiviral as well as insecticidal properties towards various pathogens. A list of various SMs from <i>Trichoderma</i> strains with identified structures and various potent bioactivities are mentioned along with their chemical SMILES in this review. This article seeks to investigate potent bioactive metabolites, methods for their discovery; challenges faced upon direct usage of <i>Trichoderma</i> formulations and acknowledges the pivotal role of bioactive metabolites in not only enhancing agroecosystems but also promoting the overall health and well-being of various organisms.</p><p><strong>Graphical abstract: </strong></p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"292-312"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Core Bacterial Microbiome in Wild Sea Cucumbers (<i>Apostichopus japonicus</i>) from the Sea of Japan.","authors":"Elena Bogatyrenko, Tatiana Dunkai, Alexandra Kim","doi":"10.1007/s12088-025-01493-w","DOIUrl":"10.1007/s12088-025-01493-w","url":null,"abstract":"<p><p>The taxonomic composition of gut bacterial communities in wild Japanese sea cucumbers, <i>Apostichopus japonicus</i>, from coastal waters of the Russian part of the Sea of Japan was identified by high-throughput sequencing. The bacterial communities were comprised mainly of the phyla Proteobacteria (38.33-57.22%), Actinobacteriota (24.24-29.93%), Firmicutes (12.01-25.12%), and Bacteroidota (1.6-2.17%) that made up a total of 94.5% of the samples studied. As the results showed, the region and habitat have a significant effect on the bacterial structure of the gut microbiome in <i>A. japonicus</i>. The invertebrates from each of the water bodies under study were characterized by their unique sets of symbiotic microorganisms. However, 32 bacterial genera were found in the animals from all of the water bodies. Of these, nine bacterial genera were the dominant taxa in terms of percentage of their representation in the samples: <i>Stappia</i> (15.89-34.68%), <i>Stenotrophomonas</i> (3.45-11.44%), <i>Bacillus</i> (1.05-7.71%), <i>Staphylococcus</i> (4.64-11.76%), <i>Rhodococcus</i> (3.07-11.08%), <i>Corynebacterium</i> (2.55-7.77%), <i>Cutibacterium</i> (15.89-34.68%), <i>Pseudomonas</i> (1.2-1.7%), and <i>Streptococcus</i> (1.09-1.57%). The discovery of bacterial genera common across all samples indicates the existence of a core microbiome potentially essential for the host's health and functions.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12088-025-01493-w.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"441-451"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13180009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hog1B is Required for Spore Germination, Stress Response and Fungal Morphogenesis in <i>Mucor lusitanicus</i>.","authors":"Phuong Anh Nguyen, Cong Huy Ha, Tuoi Thi Le, Huyen Thi Bich Vu, Trung Anh Trieu","doi":"10.1007/s12088-024-01426-z","DOIUrl":"https://doi.org/10.1007/s12088-024-01426-z","url":null,"abstract":"<p><p><i>Mucor lusitanicus</i> is a dimorphic fungus that causes the rare but fatal fungal infection mucormycosis in human with compromised immune systems. Hog1 is a mitogen-activated protein kinase (MAPK) that initiates various responsive changes in transcription and translation, mitosis, and metabolism under stress conditions. In many fungi, the Hog1 protein play a role in response to stress such as osmotic, oxidative, heavy metal stress, as well as morphogenesis and virulence. To investigate the functions of Hog1pB protein in <i>M. lusitanicus</i>, a <i>hog1B</i>-silencing strain corresponding to Hog1pB protein (ID 157309) were generated using RNAi technique. The <i>hog1B</i>-suppressed fungal strain was evaluated in morphological and stress response characteristics. The silencing strain showed a considerably lower spore germination rate and an aberrant mycelia phenotype with unusually short, septate, inflated hyphae and the presence of yeast-like structures. Furthermore, in the presence of H₂O₂ as an oxidant, the <i>hog1B</i> knock-down strain of <i>M. lusitanicus</i> exhibits decreased spore germination and viability. Under osmotic stress conditions, this silencing strain also displayed aberrant mycelia morphology and spore germination rate depletion. However, Hog1pB appears to have no influence on <i>M. lusitanicus</i> spore aerobic germination under thermal stress. The data imply that the Hog1pB protein plays an important role in <i>M. lusitanicus</i> septation, morphology, and pathogenicity. The findings suggested that the Hog1pB protein as a possible target for future mucormycosis treatment.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12088-024-01426-z.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"313-319"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147971844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sorption of Microbial Electrogenic Bacterium Strain <i>Micrococcus luteus</i> on Charged Carbon Surface.","authors":"Michael N Saksonov, Devard I Stom, Ksenia A Khramtsova, Galina O Zhdanova, Aleksander B Kupchinsky, Sergey V Alferov, Qixing Zhou, Lepakshi Barbora","doi":"10.1007/s12088-025-01483-y","DOIUrl":"https://doi.org/10.1007/s12088-025-01483-y","url":null,"abstract":"<p><p>The sorption of cells of an electrogenic strain of microorganisms <i>Micrococcus luteus</i> 1-i onto the surface of carbon fabric polarized by applying a voltage of 1 V was studied. In the absence of voltage, the sorption of <i>M. luteus</i> cells on the carbon fabric was observed to be 36.5%. The sorption of <i>M. luteus</i> cells, pre-killed by heating under similar conditions, was notably lower, at 26.5%. This value remained almost the same when the voltage was increased to 1 V. Therefore, the specified voltage value had no adverse effect on the adhesion processes of microbial cells on the electrode surface. The determination of microbial cell viability was carried out using luminescence microscopy, a Luna-II YF cell counter, and double staining of cells with fluorescent dyes, specifically acridine orange and propidium iodide. The viability of microorganisms sorbed on carbon fabric at a voltage of 1 V was maintained at a level comparable to that of the control (0 V). Furthermore, the viability of the bacterial suspension remained the same following contact with the polarized electrodes (1 V). It was demonstrated that the voltage generated in a microbial fuel cell (MFC) exhibited no detrimental impact on the viability of <i>Micrococcus luteus</i> strain cells, whether suspended in the interelectrode space or adsorbed onto the electrodes. Furthermore, the investigated microorganisms remained viable across a broad pH range of the medium, from 4.0 to 12.0. The obtained results illustrate the remarkable resilience of the <i>Micrococcus luteus</i> 1-i bacterial strain to the harsh environmental conditions that are inherent to the functioning of MFCs.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 2","pages":"431-440"},"PeriodicalIF":1.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13179977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on Survival Strategies and Social Dynamics of Microbial Communities in Biofilm.","authors":"Tamanna Jafar, Sumita Rani Saha, Sameeha Alam, Otun Saha, Khandokar Fahmida Sultana","doi":"10.1007/s12088-025-01501-z","DOIUrl":"https://doi.org/10.1007/s12088-025-01501-z","url":null,"abstract":"<p><p>Single-celled organisms colonize biotic and abiotic surfaces via intrinsic mechanisms that differentiate them from free-floating bacteria. The vital role of these mechanisms is in communication and survival in challenging environments. Particularly concerning are the biofilms formed by bacteria, which pose substantial challenges in diverse settings, ranging from medical implants to industrial pipelines. Therefore, understanding the underlying mechanisms driving biofilm formation is essential as a foundational step in devising strategies to curb or prevent their growth. The rationale behind conducting this review study is to comprehensively address the intricate issue of bacterial biofilm formation and its far-reaching implications across various domains of human life and healthcare. Bacteria within biofilms exhibit complex multicellular behaviors, orchestrated through quorum sensing, which finely regulates gene expressions. This collective behavior fundamentally transforms the traditional perception of microbes, as they navigate three-dimensional colonization, evolve, allocate responsibilities within the biofilm consortium, and adapt to varying environmental conditions. Furthermore, the escalating crisis of antibiotic resistance in bacteria presents formidable challenges in treating biofilm-associated infections such as urinary tract infections, bacterial prostatitis, chronic otitis media, lung infections, etc. Conventional antibiotics, historically effective against bacterial infections, now falter in the face of biofilm-related ailments. Hence, the pressing need to deepen our comprehension of bacterial biofilms becomes evident. Considering all this, this review will provide insight into the biofilm formation, and intercellular communication within biofilm communities, as well as their survival and socializing strategies. We also address the pressing challenge of antibiotic resistance which has emerged as a major obstacle in healthcare. Therefore, it is critical and urgent for clinicians to effectively treat biofilm-mediated infections with antibiotics that are now accessible. To achieve this, a collaborative approach involving microbiologists, chemists, and clinicians is essential to develop novel nanoparticle-based therapeutics and preventive strategies to effectively target and eradicate biofilms. In Short, our goal is to improve patient management and address the root cause of several chronic diseases that are often exacerbated by biofilm infections.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 1","pages":"95-107"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endophytic Evaluation of Entomopathogenic Fungi for Management of <i>Orseolia oryzivora</i> Infestation on Rice Plants.","authors":"O E Oyetunji, A C Odebode, F E Nwilene, B C Kotun, O A Thonda, Sesan Abiodun Aransiola, Naga Raju Maddela, Ram Prasad","doi":"10.1007/s12088-025-01521-9","DOIUrl":"https://doi.org/10.1007/s12088-025-01521-9","url":null,"abstract":"<p><p><i>Orseolia oryzivora</i> (African Rice Gall Midge-AfRGM) infestation remains a critical problem of rice in lowland agro-ecologies in Sub-Saharan Africa. Substantial and increasing yield losses caused by AfRGM are putting food security at stake in the affected areas. Insecticide application is not ecofriendly and has resulted in the emergence of resistant pest strains, thus requiring an ecofriendly substitute. Entomopathogenic fungi including <i>Metarhizium anisopliae</i> and <i>Beauveria bassiana</i> have been extensively utilized for biological control of Dipteran. An endophytic experiment was conducted to assess the impact of entomopathogenic fungi to managing AfRGM in a systemic approach. The study was set up on Completely Randomized Design (CRD) in three replications. Three strains each of <i>B. bassiana</i> and <i>M. anisopliae</i> were tested for biocontrol activity Rice seeds were coated with the inoculum of fungal strains collected from International Institute of Tropical Agriculture entomopathogenic fungi collection. The strain was prepared aseptically in the laboratory before seeding and the seed box was placed inside wooden cage in the screen house. The good agronomical practices was applied as the plant grew and five adult AfRGM were introduced to each cage for oviposition. The level of oviposition and infestation were recorded while the physiological, agronomical and yield data were collected as the plants grew. According to the findings, <i>M. anisopliae</i> IC30 strain considerably reduces AfRGM in 98.16% of non-infested tillers, while <i>M. anisopliae</i> IC20 strain controls AfRGM in 89.55% of cases. Therefore, it is clear that <i>M. anisopliae</i> may be utilized to manage the AfRGM invasion.</p><p><strong>Graphical abstract: </strong></p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 1","pages":"37-45"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal Hydroxide Composite with g-C₃N₄ Catalyzed Oxidation of Antibiotics: A Step Towards Sustainable Development Goals for Antimicrobial Resistance.","authors":"Gajendar Singh, Karimullah Shaik, Vijay S Bhalekar, Ravi P Shah","doi":"10.1007/s12088-024-01417-0","DOIUrl":"https://doi.org/10.1007/s12088-024-01417-0","url":null,"abstract":"<p><p>The present study focused on the synthesis of novel g-C₃N₄/Cu₃(OH)₂(MoO₄)₂ composite nanostructures for their instant peroxidase-mimicking activity. The composite was characterized using various techniques, including X-ray diffraction, FTIR, UV/Vis spectroscopy, SEM, and XPS. It demonstrated effective oxidative degradation catalyst activity for antibiotics like Ampicillin, Tetracycline, and Oxytetracycline in the presence of hydrogen peroxide. This catalyst activity has been demonstrated at room temperature through heterogeneous mixing. Moreover, the composite material is insoluble and recoverable, making it suitable for industrial pharmaceutical wastewater treatment.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12088-024-01417-0.</p>","PeriodicalId":13316,"journal":{"name":"Indian Journal of Microbiology","volume":"66 1","pages":"260-265"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}