Indian Journal of Dental Research最新文献_第3页

Effect of Densah Burs on Primary and Secondary Stability of Immediately Loaded Implants in Addition to Crestal Bone Loss and Gingival Probing Depth - An Evaluative Study. Densah 车针对即刻加载种植体的初级和次级稳定性以及嵴骨损失和牙龈探查深度的影响--一项评估性研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_908_23

Shraddha Rathi, N D Gupta, Sarwar Hashmi, S Abirami, Faiz Noor Khan Yusufi

{"title":"Effect of Densah Burs on Primary and Secondary Stability of Immediately Loaded Implants in Addition to Crestal Bone Loss and Gingival Probing Depth - An Evaluative Study.","authors":"Shraddha Rathi, N D Gupta, Sarwar Hashmi, S Abirami, Faiz Noor Khan Yusufi","doi":"10.4103/ijdr.ijdr_908_23","DOIUrl":"10.4103/ijdr.ijdr_908_23","url":null,"abstract":"Introduction: Osseodensification (OD) compaction increases primary stability by leaving the residual bone particles in the osteotomy site, which in turn act as an autograft. [ 1 ] Condensing the bone trabeculae through OD has demonstrated to have a potentiating influence on secondary stability. [ 2 ].Materials and methods: A split-mouth study was conducted in 40 patients to determine the effect of OD on implant success rate in terms of primary and secondary stability in situations including immediate loading of implants placed in low-density bone, which was tested using resonance frequency analysis (RFA) at the interval of 0, 6 th month. In order to assess the implant success rate, gingival probing depth and crestal bone loss (CBL) around the implant were also assessed at baseline and 6 months.Results: With respect to primary stability, at baseline, the mean RFA of Densah burs is 71.6 ± 9.5 and of conventional drills is 67.6 ± 10.4. The mean stability of Densah burs is significantly higher than conventional drills, both at baseline and after 6 months as well. CBL, at baseline, the mean CBL of Densah burs is 0.58 ± 0.11 and of conventional drills is 0.64 ± 0.12. The mean CBL of Densah burs is significantly lower than that of conventional drills for both.Conclusion: The implant stability values found in the present study were remarkable when compared between OD and conventional osteotomy techniques. Decreased loss of bone at the crest probing depth also aided in the increased success rate.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microleakage of Class II Posterior Composite Restorations with and Without use of Liners - A Comparative Study. 使用和不使用衬垫的 II 类后期复合树脂修复体的微渗漏--一项比较研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_973_23

Tariq Mohammad Shekh, Pravin Kumar, Yogender Kumar, Karishma Pathak, Sandhaya Kapoor Punia, Arun K Patnana

{"title":"Microleakage of Class II Posterior Composite Restorations with and Without use of Liners - A Comparative Study.","authors":"Tariq Mohammad Shekh, Pravin Kumar, Yogender Kumar, Karishma Pathak, Sandhaya Kapoor Punia, Arun K Patnana","doi":"10.4103/ijdr.ijdr_973_23","DOIUrl":"10.4103/ijdr.ijdr_973_23","url":null,"abstract":"Aim: This study aims to compare the effect of liner on microleakage in Class II restorations at the occlusal and gingival levels when restored with a nanocomposite.Methodology: A total of 60 mandibular molars were selected and divided into three groups. Cavities in Group A were restored with posterior nanocomposite without liner, samples of Group B were restored with posterior nanocomposite with flowable composite liner and in Group C samples were restored with posterior nanocomposite with resin-modified glass ionomer cement (RMGIC) liner. Samples were stored at 37°C in 100% humidity for 14 days. Samples were subsequently immersed in 0.5% methylene blue dye and then placed under water for 15 mins. Teeth were sectioned mesiodistally with a diamond disc and examined under a stereomicroscope.Results: All the cavities exhibited dye penetration along the occlusal and gingival margins of the restored cavities. Group A showed maximum leakage compared to Groups B and C, which was statistically significant ( P = 0.001 and P < 0.0001). No significant difference in microleakage was observed between Groups B and C. Microleakage was more in gingival margins as compared to occlusal margins in all the groups.Conclusion: Based on the results of the present study, it may be concluded that the placement of liner beneath nanocomposite restoration results in a significant reduction in microleakage.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_792_21

Ambar Khan, Rafia Untoo, Basavaraj Patthi, Ashish Singla, Monika Kumari, Ananthalekshmy Rajeev

{"title":"Oral Health-Related Quality of Life (OHRQoL) in Elderly Patients with and without Alzheimer's Disease - An Evaluative Study.","authors":"Ambar Khan, Rafia Untoo, Basavaraj Patthi, Ashish Singla, Monika Kumari, Ananthalekshmy Rajeev","doi":"10.4103/ijdr.ijdr_792_21","DOIUrl":"10.4103/ijdr.ijdr_792_21","url":null,"abstract":"Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterised by the loss of intellectual functions. The disorder is usually seen after the age of 60 years, and these elderly patients tend to experience a progressive decline in their cognitive and behavioural abilities.Aim: The present study was carried out to assess the oral health-related quality of life (OHRQoL) in elderly patients suffering from AD as compared to subjects without the disease.Materials and method: One hundred elderly subjects with AD and 150 subjects without AD were included in the study. The subjective assessment of OHRQoL was done using the General Oral Health Assessment Index (GOHAI). Demographic and oral characteristics were assessed for dentition status with the Decayed, Missing and Filled Teeth (DMFT) index, Oral Hygiene Index (OHI), prosthesis use, xerostomia and presence of oral pathologies.Results: GOHAI values were found to be statistically higher ( P = 0.0003) in the subjects with AD. The subjects with AD were found to have a higher DMFT (mean difference = 4.11), Oral Hygiene Index (OHI) scores (mean difference = 1.54), xerostomia ( P = 0.0128) and number of oral pathologies. However, the educational level ( P = 0.2603) and number of natural teeth ( P = 0.0006) were found to be lower in the group with AD.Conclusion: The present study reported that the elderly subjects suffering from AD had poorer OHRQoL than those without the disease. There is a need to comprehensively evaluate the oral health conditions of elderly patients with AD and actively provide management to improve their OHRQoL.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Caries Experience on the Oral Health-Related Quality of Life of Pre-school Children and their Families in an Indian City - An Evaluative Study. 龋齿经历对印度城市学龄前儿童及其家庭与口腔健康相关的生活质量的影响--一项评估性研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_928_21

Neha Patyal, Hemamalini Rath, Shilpa Mahapatra

{"title":"Impact of Caries Experience on the Oral Health-Related Quality of Life of Pre-school Children and their Families in an Indian City - An Evaluative Study.","authors":"Neha Patyal, Hemamalini Rath, Shilpa Mahapatra","doi":"10.4103/ijdr.ijdr_928_21","DOIUrl":"10.4103/ijdr.ijdr_928_21","url":null,"abstract":"Background: The presence of dental caries may have a negative impact on well-being of children and their parents, causing pain and discomfort, leading to poor oral health-related quality of life (OHRQoL) in them. The objective of this study was to evaluate the impact of different levels of caries experience on the OHRQoL of pre-school children and their families in Odisha, assessed using Odia version of Early Childhood Oral Health Impact Scale (Od-ECOHIS).Methodology: A cross-sectional survey was carried out on a sample of 369 pre-school children using Od-ECOHIS. Dental caries was recorded using International Caries Detection and Assessment System (ICDAS) index.Result: The total score of ECOHIS ranged from 0 to 42 with a mean of 2.4 (±5.3) and a median score of 0. The items bearing high mean scores in the child impact section were related to \"pain\", \"difficulty in drinking hot or cold beverages\", \"difficulty in eating some food\", and \"irritable or frustrated\". Though half of children (50.4%) had cavitated carious lesions, the prevalence of negative impact was 30.6%. Compared to the child being caries-free, the expected count of total Od-ECOHIS score increased by 1.54 times if the child had white spot lesion and 1.94 times if the child had a cavitated lesion.Conclusion: Presence of dental carious lesions has a significant impact on OHRQoL of pre-school children and their families measured by using Od-ECOHIS even after adjusting for SES and caregivers' perception of their children's oral health.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salivary Calprotectin Levels and Bone Mineral Density in Post-Menopausal Women With and Without Chronic Periodontitis - An Evaluative Study. 患有和未患有慢性牙周炎的绝经后妇女的唾液钙粘蛋白水平和骨矿物质密度--一项评估性研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_522_21

J Pavithra, Amitha Ramesh, Biju Thomas, N Suchetha Kumari, K P Sharmila

{"title":"Salivary Calprotectin Levels and Bone Mineral Density in Post-Menopausal Women With and Without Chronic Periodontitis - An Evaluative Study.","authors":"J Pavithra, Amitha Ramesh, Biju Thomas, N Suchetha Kumari, K P Sharmila","doi":"10.4103/ijdr.ijdr_522_21","DOIUrl":"10.4103/ijdr.ijdr_522_21","url":null,"abstract":"Introduction: Menopause is a normal developmental stage in a woman's life marking the permanent cessation of menstruation. Periodontitis and osteoporosis are noteworthy health concerns in post-menopausal women. Calprotectin is an inflammatory biomarker for precise diagnosis of periodontal disease.Materials and methods: This study was performed to evaluate the variations in salivary calprotectin levels and bone mineral density in post-menopausal women with and without chronic periodontitis. The study included 24 post-menopausal women aged 45-57 years and was divided into group 1 (12 post-menopausal women without chronic periodontitis) and group 2 (12 post-menopausal women with chronic periodontitis). Unstimulated salivary samples, panoramic radiographs and clinical examination were performed.Results: The collected samples were combined with CALPRO antibody with horseradish peroxide (HRP) that results in the formation of antigen-antibody complex. Tetramethylbenzidine (TMB) solution was added that turned blue. Colour change was measured at 450nm. A human ELISA kit was used. Data collected were sent for statistical analysis.Discussion: There was a statistically significant difference in salivary calprotectin levels between groups 1 and 2 ( P = 0.016) and no statistical difference in mean bone mineral density levels between the two groups ( P = 0.235). A positive correlation was seen between salivary calprotectin levels and bone mineral density in group 2 ( P = 0.013).","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Lip Repositioning in Search of Aesthetics - A Case Series. 追求美感的唇部手术复位--病例系列。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_835_23

Sk Aziz Ikbal, Zeba R Siddiqui, Siddhartha Dutta, Tasneem Fatima, Roopanshi Mehrotra, Surendra K Yadav

引用次数: 0

Effect of Periodontal Therapy on Rheumatoid Disease Activity in Patients on Anti-Rheumatoid Drugs - A Prospective Study. 牙周治疗对服用抗类风湿药物患者类风湿病活动性的影响--一项前瞻性研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-08-22 DOI: 10.4103/ijdr.ijdr_535_23

Arunachalam Kaveri, Velayudham Rajendran, Tukaram Kshirsagar Jaishree, Krishnamoorthy Malathi, Mohanasundaram Kavitha

{"title":"Effect of Periodontal Therapy on Rheumatoid Disease Activity in Patients on Anti-Rheumatoid Drugs - A Prospective Study.","authors":"Arunachalam Kaveri, Velayudham Rajendran, Tukaram Kshirsagar Jaishree, Krishnamoorthy Malathi, Mohanasundaram Kavitha","doi":"10.4103/ijdr.ijdr_535_23","DOIUrl":"10.4103/ijdr.ijdr_535_23","url":null,"abstract":"Aim: The aim of this clinical trial rheumatoid arthritis-chronic periodontitis (RA-CP) is to assess the effect of non-surgical periodontal therapy in RA patients.Materials and methods: Sixty RA patients taking disease-modifying anti-rheumatoid drugs (DMARD) with CP were selected from the Institute of Rheumatology, Madras Medical College, randomised into the intervention group (IG) and control group (CG). IG received non-surgical periodontal therapy after the screening visit, but CG did not receive treatment until the 3 months study period. Periodontal parameters were recorded at baseline and after 3 months for both groups. Rheumatoid Disease activity (RD activity) was assessed using disease activity score (DAS28), inclusive of tender joints count (TJC), swollen joints count (SJC), visual analog scale (VAS), and erythrocyte sedimentation rate (ESR) for both groups at baseline and after 3 months.Results: At the end of 3 months, IG had significant reduction in RA parameters such as tender joints count (0.0005), swollen joints count (0.0005), ESR (0.003), VAS score (0.0005), and DAS28 values (0.0005) compared to CG. Periodontal parameters at the end of 3 months were also significantly reduced in IG than in CG.Conclusion: Non-surgical periodontal therapy might have reduced the burden of systemic inflammatory markers, thus reducing severity of RA in IG. Reduction in tenderness and swelling of joints in the upper arm might have enabled the patients in IG to perform better oral hygiene maintenance procedures.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Quantitative Assessment of Apoptotic Index with Varying Histological Degree of Dysplasia and Squamous Cell Carcinoma of Oral Cavity - A Light Microscopic Study. 不同组织学程度的口腔增生异常和鳞状细胞癌凋亡指数的定量评估--一项光学显微镜研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-08-22 DOI: 10.4103/ijdr.ijdr_382_23

Chitrapriya Saxena, Vijay Wadhwan, Vijay Kumar, Aparna Singh, Siddharth Anand, Asib Ahmad

{"title":"A Quantitative Assessment of Apoptotic Index with Varying Histological Degree of Dysplasia and Squamous Cell Carcinoma of Oral Cavity - A Light Microscopic Study.","authors":"Chitrapriya Saxena, Vijay Wadhwan, Vijay Kumar, Aparna Singh, Siddharth Anand, Asib Ahmad","doi":"10.4103/ijdr.ijdr_382_23","DOIUrl":"10.4103/ijdr.ijdr_382_23","url":null,"abstract":"Aim and objective: The aim of the present study was to quantitatively assess the apoptotic index at a light microscopic level in hyperkeratosis with varying histological degrees of dysplasia and different grades of oral squamous cell carcinoma (OSCC) and its correlation with prognostic significance.Study design: The study included the histo-pathologically diagnosed cases of hyperkeratosis with varying degrees of dysplasia and different grades of OSCC, which were retrieved from the archives of the department, and clinical details were retrieved from the case records of the patients. The sample size consisted of 80 biopsied cases, divided into seven groups of 10 experimental cases and one group of 10 cases of normal mucosa as a control group.Results: The age range of 50-59 shows maximum patients of hyperkeratosis with varying degrees of dysplasia and OSCC. Maximum apoptotic bodies were seen in cases of severe dysplasia and well-differentiated cases of OSCC. There was an observational difference noticed in apoptotic bodies between the patients who had less than 1-year disease-free survival rate.Conclusions: The apoptotic cells are being seen using routine light microscopy techniques with hematoxylin and eosin staining. In different grades of squamous cell carcinoma, a decrease in the apoptotic count was noticed from well-differentiated squamous cell carcinoma toward poorly differentiated squamous cell carcinoma cases. Increased mean apoptotic bodies were observed in patients showing less than 1 year of survival.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Andrographis paniculata Herbal Extract on Cytotoxicity, Proliferation and Osteogenic/Odontogenic Differentiation of Human Dental Pulp Stem Cells: An In Vitro Study. 穿心莲草本提取物对人牙髓干细胞细胞毒性、增殖和成骨/成牙分化的影响：体外研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_907_22

Savitha B Naik, N Kiran Kumar, P Annie Swathisha, Biji Brigit, H S Preetham, Chella S Karumaran

{"title":"Effect of Andrographis paniculata Herbal Extract on Cytotoxicity, Proliferation and Osteogenic/Odontogenic Differentiation of Human Dental Pulp Stem Cells: An In Vitro Study.","authors":"Savitha B Naik, N Kiran Kumar, P Annie Swathisha, Biji Brigit, H S Preetham, Chella S Karumaran","doi":"10.4103/ijdr.ijdr_907_22","DOIUrl":"10.4103/ijdr.ijdr_907_22","url":null,"abstract":"Background: Research has been conducted to assess the regenerative potential of dental pulp stem cells (DPSCs) following pretreatment of stem cells with certain molecules, bioactive compounds, plant extract and physical stimulation. Andrographis paniculata (AP) herbal extract with important medicinal properties is proven to have a preosteogenic effect on osteoblasts.Aim: This study aimed to determine the effect of various concentrations of AP extract on the cytotoxicity and osteogenic and odontogenic potential of DPSCs.Methods and material: Dental pulp stem cells were subjected to treatment with various concentrations of AP herbal extract (7 ug/ml, 5.2 ug/ml, 3.5 ug/ml, 1.7 ug/ml and 0.8 ug/ml), following which the cells were subjected to tests-3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) analysis for cytotoxicity and real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test for expression of genes (bone morphogenetic protein (BMP), osteocalcin (OCN), dentin sialophosphoprotein (DSPP) and alkaline phosphatase (ALP)).Results: AP extract at concentration of 0.8 ug/ml-5.2 ug/ml had no cytotoxicity supporting cell growth. 3.5 ug/ml showed significant upregulation of genes on the third day.Conclusion: AP, a commonly occurring medicinal plant through its effect on DPSCs, could serve as an effective pretreatment modality for cell-based regenerative therapy and vital pulp therapy.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral Risk Factors in Patients with Cancer Undergoing Chemotherapy - A Pilot Study. 接受化疗的癌症患者的口腔风险因素--一项试点研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-08-22 DOI: 10.4103/ijdr.ijdr_516_23

Anupama Aradya, P K Kiran, K N Raghavendra Swamy, Vidya G Doddawad, Narahari Ranganatha, Koduru Sravani

{"title":"Oral Risk Factors in Patients with Cancer Undergoing Chemotherapy - A Pilot Study.","authors":"Anupama Aradya, P K Kiran, K N Raghavendra Swamy, Vidya G Doddawad, Narahari Ranganatha, Koduru Sravani","doi":"10.4103/ijdr.ijdr_516_23","DOIUrl":"10.4103/ijdr.ijdr_516_23","url":null,"abstract":"Background: Treatment modalities for cancer including surgery, radiotherapy and chemotherapy, have some complications even in the oral cavity. The literature describes oral lesions that may arise as a result of chemotherapy. However, information regarding oral symptoms in advanced cancer patients is poor.Objective: To identify the oral manifestations like oral mucositis, dry mouth and loss of taste in patients undergoing chemotherapy treatment.Methods: We evaluated 60 patients affected by malignancy undergoing chemotherapy treatment. The clinical and pathological data such as age, gender, diagnosis of malignancy and types of treatments with anticancer chemotherapeutic drug treatment, were obtained. Patients were routinely evaluated for the presence of oral mucositis based on the Common Terminology Criteria for Adverse Events (CTCAE) v5.0 scale for adverse effects and graded. Other findings like dry mouth and loss of taste were recorded.Results: Of the 60 patients, 40 (66.6%) were male, and 20 (33.3%) females with a mean age of 53.7 years. Most patients about 63% and 83% were diagnosed with dry mouth and loss of taste, respectively and 71% of patients had mucositis. Chemotherapy drugs like Cyclophosphamide, carboplatin, nanoxel, paclitaxel, oxaliplatin, docetaxel and doxorubicin, were directly associated with oral mucositis.Conclusion: Patients treated with chemotherapy for cancer most often suffer from a multitude of intense and debilitating oral dysfunctions. Oral lesions found in patients undergoing chemotherapy were mucositis, dry mouth and loss of taste. These adverse effects and an appropriate symptomatic therapy need to be discussed with the patients. Chemotherapy has a significant but transient effect on the oral symptoms.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0