Indian Journal of Dental Research最新文献_第4页

Comparative Evaluation of Success of NeoPutty Mineral Trioxide Aggregate ® with Formocresol as Pulpotomy Medicaments in Primary Molars: A Clinical Study. NeoPutty Mineral Trioxide Aggregate® 与福莫甲酚作为小磨牙牙髓切除术药物的成功率比较评估：临床研究。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-08-22 DOI: 10.4103/ijdr.ijdr_730_23

Sonu Acharya, Deepa Gurunathan

{"title":"Comparative Evaluation of Success of NeoPutty Mineral Trioxide Aggregate ® with Formocresol as Pulpotomy Medicaments in Primary Molars: A Clinical Study.","authors":"Sonu Acharya, Deepa Gurunathan","doi":"10.4103/ijdr.ijdr_730_23","DOIUrl":"10.4103/ijdr.ijdr_730_23","url":null,"abstract":"Objective: This clinical study was aimed to investigate the clinical and radiographic outcomes of NeoPutty MTA ® (Nusmile), a novel mineral trioxide aggregate (MTA) pulpotomy material, in primary teeth of children aged 4-6 years.Methods: An in vivo study was done in children aged 4-6 years old. A total of 50 primary second molar teeth were included in the study, with 25 of them undergoing treatment with formocresol (FC) and 25 receiving treatment with NeoPutty MTA ® . The subjects were divided into two groups for treatment: the first group received a treatment involving a 1:5 dilution of Buckley's FC. The second group, however, underwent treatment with NeoPutty MTA ® . This study employs a meticulous approach to evaluate the impact of different treatments on a significant number of molar teeth, using FC and NeoPutty MTA ® as the respective treatment methods. The demographics of the subject pool are well-documented, comprising a balance of male and female participants. The technique employed for pulp removal and the subsequent management of bleeding are outlined, underscoring the thoroughness of the process.Results: At 12 months, the NeoPutty MTA ® pulpotomy group showed a significantly higher success rate clinically (96%) compared to the FC group (72%) ( P < 0.05), but radiographically although NeoPutty MTA ® was better (92%) than FC (82%), it was not statistically significant. NeoPutty ® -treated teeth exhibited no signs of pain or discomfort and demonstrated better pulp vitality compared to the FC group.Conclusion: NeoPutty MTA ® demonstrated superior clinical success rates and better radiographic outcomes compared to traditional FC pulpotomy.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dental Research and Noncommunicable Diseases. 牙科研究与非传染性疾病。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-10-03 DOI: 10.4103/ijdr.ijdr_664_24

S M Balaji

引用次数: 0

Cytotoxicity and Alkaline Phosphatase Activity of Curcumin, Aloin and MTA on Human Dental Pulp Cells. 姜黄素、芦荟素和 MTA 对人类牙髓细胞的细胞毒性和碱性磷酸酶活性

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-08-22 DOI: 10.4103/ijdr.ijdr_1184_21

Dilara Dinc, Mehmet F Seyhan, Oya Aktoren

{"title":"Cytotoxicity and Alkaline Phosphatase Activity of Curcumin, Aloin and MTA on Human Dental Pulp Cells.","authors":"Dilara Dinc, Mehmet F Seyhan, Oya Aktoren","doi":"10.4103/ijdr.ijdr_1184_21","DOIUrl":"10.4103/ijdr.ijdr_1184_21","url":null,"abstract":"Aim: The objective of this in-vitro study was to assess the cytotoxicity and alkaline phosphatase (ALP) activity of curcumin and aloin extracted from Curcuma longa and Aloe vera , and mineral trioxide aggregate (MTA) on human dental pulp stem cells.Methods: Human dental pulp stem cells (Lonza Group, Switzerland), curcumin (Sigma-Aldrich, USA), aloin (Sigma-Aldrich, USA), and ProRoot MTA (Dentsply, USA) were used in the study. 2.5-6.75-12.5-25-50 μg/ml of curcumin and aloin, 25%-50%-75%-100% of MTA were prepared; pulp cells unincubated with a material were assessed as controls. Cytotoxicity of all doses/concentrations of materials was analysed on days of 1, 2, 3, and 7 by WST-1 test. 2.5-6.75 μg/ml of curcumin and aloin, 25%-50% of MTA incubated with cells for 7-14 days were evaluated for ALP activity by ELISA test. Data was statistically analysed by One Way ANOVA, Tukey, and Sidak tests at GraphPad Prism 6.Results: The findings have shown that 2.5 μg/ml of curcumin, all doses of aloin, 25% and 50% of MTA increased cell proliferation significantly on day 1 ( P < 0.05). Curcumin, aloin, and MTA decreased the cell viability as dose/concentration and exposure time increased. All materials have shown no significant increases in ALP activity ( P > 0.05) on 7 and 14 days.Conclusion: Data of this study revealed that 2.5 - 6.75 μg/ml of curcumin/aloin, 25%-50% of MTA have promoted cell viability and proliferation of human dental pulp cells; and none of the materials have significantly increased the ALP activity at 7-14 days.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Stresses Generated with Two Different Self-Ligating Orthodontic Bracket Systems - A Finite Element Analysis. 评估两种不同的自锁式正畸托槽系统产生的应力--有限元分析。

Indian Journal of Dental Research Pub Date : 2024-04-01 Epub Date: 2024-09-14 DOI: 10.4103/ijdr.ijdr_937_23

Mohit Awaradi, Roshan M Sagarkar, Prashantha G Shivamurthy, Silju Mathew, Sharanya Sabrish, Nirajita Bhaduri

{"title":"Evaluation of Stresses Generated with Two Different Self-Ligating Orthodontic Bracket Systems - A Finite Element Analysis.","authors":"Mohit Awaradi, Roshan M Sagarkar, Prashantha G Shivamurthy, Silju Mathew, Sharanya Sabrish, Nirajita Bhaduri","doi":"10.4103/ijdr.ijdr_937_23","DOIUrl":"10.4103/ijdr.ijdr_937_23","url":null,"abstract":"Aim: To determine stresses generated in the posterior teeth region by two different self-ligating systems, 3M Unitek SmartClip and Damon Q Self-ligating brackets, using the finite element method (FEM).Methodology: Computed tomography (CT) scan of maxilla was taken using Mimics software, and the Dicom data were imported into Hypermesh 13.0 software to convert it into a geometric model and then into FEM. Physical models of both the brackets were constructed and positioned on the teeth. Post archwire modeling, contact is defined between the bracket slot and 0.014\" NiTi arch wire. The final assembled model was exported to ANSYS 12.1 for analysis, and 60 grams of load was applied at the ends of the arch wire.Results: On using 0.014\" CuNiTi in both the bracket systems, stresses generated on the root surface were found to be maximum on the first molar region, followed by the first premolar, second molar, canine, and second premolar regions. Comparison between the two bracket systems showed differences in the stresses generated, where higher stresses were generated at all regions in the Damon Q bracket system, except the inter-second premolar region.Conclusion: Maximum stresses were observed with the 3M Unitek SmartClip bracket system at the second premolar cervical region when compared to the Damon Q system. In both the cortical bone and cancellous bone, maximum stresses were observed at the second premolar cervical in the Damon Q bracket system region.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Evaluation of Implant-Protected Occlusion in Partially Edentulous Fixed Restoration Using Qualitative and Quantitative Assessment – A Prospective Clinical Trial 通过定性和定量评估对部分无牙颌固定修复体的种植体保护性咬合进行比较评估 - 一项前瞻性临床试验

Indian Journal of Dental Research Pub Date : 2024-02-16 DOI: 10.4103/ijdr.ijdr_191_23

Ramesh Chowdhary, S. Bukkapatnam

{"title":"Comparative Evaluation of Implant-Protected Occlusion in Partially Edentulous Fixed Restoration Using Qualitative and Quantitative Assessment – A Prospective Clinical Trial","authors":"Ramesh Chowdhary, S. Bukkapatnam","doi":"10.4103/ijdr.ijdr_191_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_191_23","url":null,"abstract":"\u0000 \u0000 \u0000 To compare and evaluate the occlusal variability/discrepancy recorded using qualitative (articulating paper) and quantitative (T-scan) techniques in partially edentulous implant-supported restorations.\u0000 \u0000 \u0000 \u0000 A total of 20 patients in the age group of 25–61 yrs participated in this study. All the patients had more than one tooth replaced with implant-supported prosthesis. After three months of restoration, occlusion reevaluated was carried out using qualitative (articulating paper) and quantitative (T-scan). T-scan data were used to measure implant occlusion time, occlusion time, and the relative occlusal force (ROFs) on implant prosthesis. And the data were statistically evaluated.\u0000 \u0000 \u0000 \u0000 The T-scan values showed high points on the implants in most of the patients, which could not be evaluated by that of articulating paper outcomes.\u0000 \u0000 \u0000 \u0000 The occlusal harmony achieved from using qualitative analysis of articulating paper was not supported by the finding of the quantitative analysis (T-scan). Also the T-scan provided the time interval of occlusion of the implant-supported restorations, which would help in better defining the implant-protected occlusal.\u0000 \u0000 \u0000 \u0000 The T-scan occlusal analysis system provides ROF and time intervals of occlusal contact. This allows accurate occlusal equilibration of implant-supported restoration according to implant protected occlusal concept.\u0000","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139961350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An In Vitro Comparative Study of the Push-out Bond Strengths of Various Endodontic Sealers to Radicular Dentin 各种牙髓密封剂与根管牙本质的推出粘接强度体外比较研究

Indian Journal of Dental Research Pub Date : 2024-02-16 DOI: 10.4103/ijdr.ijdr_708_22

Mohamed Abdelaziz El Sayed, Safiya Saeed Alderei

{"title":"An In Vitro Comparative Study of the Push-out Bond Strengths of Various Endodontic Sealers to Radicular Dentin","authors":"Mohamed Abdelaziz El Sayed, Safiya Saeed Alderei","doi":"10.4103/ijdr.ijdr_708_22","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_708_22","url":null,"abstract":"\u0000 \u0000 \u0000 The bond strength of an endodontic sealer to the root dentin is an important factor in maintaining the integrity of the root canal seal. The present study aimed to assess the push-out bond strength of three endodontic sealers used with the single-cone obturation technique.\u0000 \u0000 \u0000 \u0000 The root canals of 40 central maxillary incisors were instrumented using ProTaper Universal NiTi rotary files. The roots were divided into 4 groups (N = 10) according to the type of root canal sealers: Group 1 (control group): AH Plus/Gutta-percha lateral condensation technique (LC); Group 2: AH Plus/Gutta-percha single-cone technique (SC); Group 3: GuttaFlow 2/SC; Group 4: Realseal SE/SC. After obturation, each tooth was prepared for push-out assessment. The total and sectional push-out bond strengths were measured and statistically analysed. Furthermore, failure modes were identified microscopically.\u0000 \u0000 \u0000 \u0000 The results indicated that samples in the first group showed the highest total and sectional bond strengths. Samples from other groups showed statistically similar total bond strengths. The highest sectional bond strength was found mainly in the apical root sections. Cohesive failure was predominant for the first group, whereas adhesive failure was predominant in the other groups.\u0000 \u0000 \u0000 \u0000 It could be concluded that the dentin bond strengths of the tested sealers used with the single-cone technique were nearly similar but lower than those of AH Plus/LC. The highest sectional bond strength was observed in the apical thirds. The failure mode was mostly cohesive for AH Plus/LC and adhesive for sealers used with the single-cone obturation technique.\u0000","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Choosing Periodontology for Specialty Specialization: Perspective of Dental Undergraduate Students 选择牙周病学作为专科专业：从牙科本科生的角度看牙周病学

Indian Journal of Dental Research Pub Date : 2024-02-08 DOI: 10.4103/ijdr.ijdr_957_21

Prabhati Gupta, Z. Chowdhary, Vikas Singh, Aashima Bajaj, Disha Gupta, Monika Loitongbam

{"title":"Choosing Periodontology for Specialty Specialization: Perspective of Dental Undergraduate Students","authors":"Prabhati Gupta, Z. Chowdhary, Vikas Singh, Aashima Bajaj, Disha Gupta, Monika Loitongbam","doi":"10.4103/ijdr.ijdr_957_21","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_957_21","url":null,"abstract":"\u0000 \u0000 \u0000 The attitudes of dental students to study a particular specialty of dentistry in post-graduation are of great importance as these facilitate workforce planning in the dental sector.\u0000 \u0000 \u0000 \u0000 To assess the attitude of dental students towards choosing periodontology as their future career and to explore demographic variables that affect their choice.\u0000 \u0000 \u0000 \u0000 A cross-sectional survey based on a questionnaire was conducted, including students of the third and fourth years and interns of the dental college. Twenty-seven questions, graded on a Likert scale (5-point) were included in the questionnaire, and the responses were categorised via three attitudes: negative (score 0–21), neutral (score 22–44) and positive (score 45–64). The Chi-square test for proportions was used to examine the differences between groups.\u0000 \u0000 \u0000 \u0000 Among 114 participants, 53 (46.5%) were males and 61 (53.5%) were females. One-third of the respondents had a positive attitude towards selecting periodontology as their future career, and the majority had a neutral perspective, with a few students having a negative attitude (20.2%). Out of the total, 34.2% of respondents had a positive attitude, and 45.6% showed a neutral attitude or perspective.\u0000 \u0000 \u0000 \u0000 Efforts should be intensified, and undergraduate (UG) students should be motivated by broadening the scope of the field in the UG curriculum by the dental council so that the students show considerable interest in pursuing the field as their future career.\u0000","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139853555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Varied Time Interval and Micro-Current (Direct) on the Level of Biomarker (IL-6) and Rate of Tooth Movement: An Animal Study 不同时间间隔和微电流（直流）对生物标志物（IL-6）水平和牙齿移动速度的影响：一项动物研究

Indian Journal of Dental Research Pub Date : 2024-02-08 DOI: 10.4103/ijdr.ijdr_2_23

Parnita Dwivedi, Ashish Agrawal, Subash Chandra Gupta, Tehmin Chou

{"title":"The Effect of Varied Time Interval and Micro-Current (Direct) on the Level of Biomarker (IL-6) and Rate of Tooth Movement: An Animal Study","authors":"Parnita Dwivedi, Ashish Agrawal, Subash Chandra Gupta, Tehmin Chou","doi":"10.4103/ijdr.ijdr_2_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_2_23","url":null,"abstract":"\u0000 \u0000 \u0000 Exogenous application of direct current (DC) on piezoelectric biopolymers results in biochemical modifications in the intracellular/extracellular regions which profoundly affects the pace of bone turnover. A qualitative examination of DC (waveform and frequency) provides ideal qualities of current.\u0000 \u0000 \u0000 \u0000 20 female Wistar rats (Rattus norvegicus) were randomly selected and divided into control (group 1–4 rats) with orthodontic appliance (OA) and experimental groups (OA + Micro-current (MC). Experimental groups were subdivided into four groups (group 2–20 μA/5 sec, 3-20 μA/10 sec, 4-15 μA/5 sec, 5-15 μA/10 sec with four rats in each). The tooth movement was recorded every 24th hours for 7 days. Gingival crevicular fluid (GCF) was collected 6 hr, 12 hr, 24 hr, 3rd day and 168 hrs with the absorbent paper points at specific location around the tooth in control and experiment groups. Histopathological analysis was done on 168 hrs to assess the osteoclastic activity around the root. Interleukin-6 (IL-6) concentration was accessed using enzyme-linked immunosorbent assay (ELISA). The data were subjected to one-way ANOVA and Tukey’s post hoc test.\u0000 \u0000 \u0000 \u0000 There was a statistically significant difference in tooth movement, group 3 (20 μA/10 sec) showed an increased rate of tooth movement on the 168 hrs. The level of IL-6 was maximum on 72 hrs in experimental group 3.\u0000 \u0000 \u0000 \u0000 The study showed time interval/frequency, the waveform, and the amount of current play a significant role in determining bone turnover and rate of tooth movement.\u0000","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139791940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Choosing Periodontology for Specialty Specialization: Perspective of Dental Undergraduate Students 选择牙周病学作为专科专业：从牙科本科生的角度看牙周病学

Indian Journal of Dental Research Pub Date : 2024-02-08 DOI: 10.4103/ijdr.ijdr_957_21

Prabhati Gupta, Z. Chowdhary, Vikas Singh, Aashima Bajaj, Disha Gupta, Monika Loitongbam

{"title":"Choosing Periodontology for Specialty Specialization: Perspective of Dental Undergraduate Students","authors":"Prabhati Gupta, Z. Chowdhary, Vikas Singh, Aashima Bajaj, Disha Gupta, Monika Loitongbam","doi":"10.4103/ijdr.ijdr_957_21","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_957_21","url":null,"abstract":"\u0000 \u0000 \u0000 The attitudes of dental students to study a particular specialty of dentistry in post-graduation are of great importance as these facilitate workforce planning in the dental sector.\u0000 \u0000 \u0000 \u0000 To assess the attitude of dental students towards choosing periodontology as their future career and to explore demographic variables that affect their choice.\u0000 \u0000 \u0000 \u0000 A cross-sectional survey based on a questionnaire was conducted, including students of the third and fourth years and interns of the dental college. Twenty-seven questions, graded on a Likert scale (5-point) were included in the questionnaire, and the responses were categorised via three attitudes: negative (score 0–21), neutral (score 22–44) and positive (score 45–64). The Chi-square test for proportions was used to examine the differences between groups.\u0000 \u0000 \u0000 \u0000 Among 114 participants, 53 (46.5%) were males and 61 (53.5%) were females. One-third of the respondents had a positive attitude towards selecting periodontology as their future career, and the majority had a neutral perspective, with a few students having a negative attitude (20.2%). Out of the total, 34.2% of respondents had a positive attitude, and 45.6% showed a neutral attitude or perspective.\u0000 \u0000 \u0000 \u0000 Efforts should be intensified, and undergraduate (UG) students should be motivated by broadening the scope of the field in the UG curriculum by the dental council so that the students show considerable interest in pursuing the field as their future career.\u0000","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Varied Time Interval and Micro-Current (Direct) on the Level of Biomarker (IL-6) and Rate of Tooth Movement: An Animal Study 不同时间间隔和微电流（直流）对生物标志物（IL-6）水平和牙齿移动速度的影响：一项动物研究

Indian Journal of Dental Research Pub Date : 2024-02-08 DOI: 10.4103/ijdr.ijdr_2_23

Parnita Dwivedi, Ashish Agrawal, Subash Chandra Gupta, Tehmin Chou

{"title":"The Effect of Varied Time Interval and Micro-Current (Direct) on the Level of Biomarker (IL-6) and Rate of Tooth Movement: An Animal Study","authors":"Parnita Dwivedi, Ashish Agrawal, Subash Chandra Gupta, Tehmin Chou","doi":"10.4103/ijdr.ijdr_2_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_2_23","url":null,"abstract":"\u0000 \u0000 \u0000 Exogenous application of direct current (DC) on piezoelectric biopolymers results in biochemical modifications in the intracellular/extracellular regions which profoundly affects the pace of bone turnover. A qualitative examination of DC (waveform and frequency) provides ideal qualities of current.\u0000 \u0000 \u0000 \u0000 20 female Wistar rats (Rattus norvegicus) were randomly selected and divided into control (group 1–4 rats) with orthodontic appliance (OA) and experimental groups (OA + Micro-current (MC). Experimental groups were subdivided into four groups (group 2–20 μA/5 sec, 3-20 μA/10 sec, 4-15 μA/5 sec, 5-15 μA/10 sec with four rats in each). The tooth movement was recorded every 24th hours for 7 days. Gingival crevicular fluid (GCF) was collected 6 hr, 12 hr, 24 hr, 3rd day and 168 hrs with the absorbent paper points at specific location around the tooth in control and experiment groups. Histopathological analysis was done on 168 hrs to assess the osteoclastic activity around the root. Interleukin-6 (IL-6) concentration was accessed using enzyme-linked immunosorbent assay (ELISA). The data were subjected to one-way ANOVA and Tukey’s post hoc test.\u0000 \u0000 \u0000 \u0000 There was a statistically significant difference in tooth movement, group 3 (20 μA/10 sec) showed an increased rate of tooth movement on the 168 hrs. The level of IL-6 was maximum on 72 hrs in experimental group 3.\u0000 \u0000 \u0000 \u0000 The study showed time interval/frequency, the waveform, and the amount of current play a significant role in determining bone turnover and rate of tooth movement.\u0000","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0