Indian Journal of Dental Research最新文献

Implant Osteoblast Differentiation Under Low-Magnitude High-Frequency Vibrational Loading - An In Vitro Study. 低强度高频振动载荷下种植体成骨细胞分化的体外研究。

Indian Journal of Dental Research Pub Date : 2025-06-27 DOI: 10.4103/ijdr.ijdr_125_24

Sachin Chaware, Chetan Kakade, Siddhesh Borse

{"title":"Implant Osteoblast Differentiation Under Low-Magnitude High-Frequency Vibrational Loading - An In Vitro Study.","authors":"Sachin Chaware, Chetan Kakade, Siddhesh Borse","doi":"10.4103/ijdr.ijdr_125_24","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_125_24","url":null,"abstract":"Introduction: The present study aimed to assess the microscopic effects of low-magnitude high frequency on dental implant surfaces using MG-63 cells and vertical vibration loading.Materials and methods: 24 dental implants wrapped with collagen membranes were placed in a 12-well plate filled with MG-63 cell culture. A vibration device was constructed using 3D printing technology and employed a vertical vibration system. Three vibration cycles were utilized, including frequencies of 30 Hz, 60 Hz, and 90 Hz. Each cycle had durations of 1, 5, and 10 min/h, with a total duration of 6 h. The control group underwent no vibrational loading. After 24 h, analysis was conducted using an inverted microscope and a spectrophotometer. Alkaline phosphatase (ALP) expression was assessed using an ALP Kit.Results: The study yielded highly significant results (P < 0.001). cell activity was found to be highest with 30 Hz vibration loading compared to both 60 Hz and 90 Hz (P < 0.001). Among the various durations tested, the 30 Hz vibration with a 5-min cycle per hour, totalling 6 h, exhibited the highest cell activity. Additionally, ALP expression was most pronounced with 30 Hz vibrational loading. The cells displayed a dark green appearance surrounded by a pale green extracellular matrix.Conclusion: The highest cell activity and ALP expression were reported with the 30 Hz vibrational loading lasting 5 min/h, over a total duration of 6 h. However, a decline in cell activity was observed with both increased duration and frequency.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterisation of Macrophage Sub-populations in Oral Lichen Planus using CD64 and CD163 - An Evaluative Study. CD64和CD163对口腔扁平苔藓巨噬细胞亚群特征的评价研究

Indian Journal of Dental Research Pub Date : 2025-06-27 DOI: 10.4103/ijdr.ijdr_458_24

L Surya Surendran, Anna P Joseph, Varun B Raghavan Pillai, Freeda Mary Selvaraj

{"title":"Characterisation of Macrophage Sub-populations in Oral Lichen Planus using CD64 and CD163 - An Evaluative Study.","authors":"L Surya Surendran, Anna P Joseph, Varun B Raghavan Pillai, Freeda Mary Selvaraj","doi":"10.4103/ijdr.ijdr_458_24","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_458_24","url":null,"abstract":"Background: Oral lichen planus (OLP) stands out as one of the prevalent chronic inflammatory conditions affecting the oral cavity, with its aetiology linked to immune-mediated processes. Macrophages play a pivotal role in orchestrating immunological responses within the oral environment. While existing literature suggests significant involvement of macrophages in the progression and persistence of OLP, insights into their specific phenotype expression remain limited.Aims: This study aimed to evaluate and compare the expression of M1 and M2 macrophages in reticular and erosive OLP using CD64 and CD163.Materials and methods: This cross-sectional study comprised 15 clinically diagnosed and histopathologically confirmed cases of OLP, along with 15 cases of normal oral mucosa. Densities of CD64+ M1 and CD163+ M2 macrophages were assessed in the epithelial and sub-epithelial areas.Results: A significant correlation between macrophage sub-populations in OLP was observed (P < 0.001). Within OLP, higher densities of CD64+ M1 and CD163+ M2 macrophages were detected in sub-epithelial areas. Notably, M1 macrophage predominated over M2 macrophage sub-populations in OLP, potentially implicating them in the immunopathogenesis.Conclusions: These findings hold importance for future investigations targeting therapeutic interventions for OLP.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retentive Strength of Stainless-Steel Crown with Three Different Luting Cements - An In vitro Study. 三种不同固位剂对不锈钢冠固位强度的体外研究。

Indian Journal of Dental Research Pub Date : 2025-06-16 DOI: 10.4103/ijdr.ijdr_65_25

Amit Vilas Tandulkar, Lumbini Pathivada, Nishita Garg, Munagala Karthik Krishna, Ramakrishna Yeluri, Sayani Roy

{"title":"Retentive Strength of Stainless-Steel Crown with Three Different Luting Cements - An In vitro Study.","authors":"Amit Vilas Tandulkar, Lumbini Pathivada, Nishita Garg, Munagala Karthik Krishna, Ramakrishna Yeluri, Sayani Roy","doi":"10.4103/ijdr.ijdr_65_25","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_65_25","url":null,"abstract":"Background: Although stainless-steel crowns (SSCs) have a high clinical success rate, a key reason for its clinical failure is loss of crown due to cementation failure. Therefore, the choice of cementation material has an important effect on SSC retention.Aim: To evaluate the retention strength of SSCs luted on primary molars with glass ionomer cement (GIC), resin-modified glass ionomer cement (RMGIC) and resin-based cement.Materials and methods: A total of 45 freshly extracted human primary molars were prepared to receive SSCs and randomly divided into three equal groups, to receive the different luting cements: conventional glass ionomer, resin-modified glass ionomer and resin luting cement. The teeth were then stored in artificial saliva for 24 h. The retentive strength of the crowns was determined using a specially designed Universal Testing Machine.Statistical analysis: To compare the mean retentive strength between cements, ANOVA with post hoc test was applied.Results: Mean retentive strength for GC GOLD Label 1 group was 230.30 ± 13.46; GC FujiCEM group was 194.78 ± 13.03; and 269.25 ± 11.28 for the GC G-CEM One group. A comparison of luting cement showed the retentive strength of GC G-CEM One cement significantly higher than the rest of the two cements (P < 0.001). The retentive strength of GC GOLD Label 1 cement was significantly higher than GC FujiCEM cement (P < 0.001).Conclusion: Resin cement (GC G-CEM One) significantly improved crown retention when compared with RMGIC (GC FujiCem) and GIC (GC Gold label 1).","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Skeletal Class III Malocclusion in an Adolescent Using Maxillary Skeletal Expander and Facemask - A Case Report. 上颌骨扩张器与面罩治疗青少年骨骼III类错颌1例。

Indian Journal of Dental Research Pub Date : 2025-06-05 DOI: 10.4103/ijdr.ijdr_754_24

Nandita Krishnaswamy

引用次数: 0

Mitigation of Mouth Opening in Oral Submucous Fibrosis with Nutraceutical Products: A Network Meta-Analysis. 营养保健品减轻口腔黏膜下纤维化患者的开口：一项网络荟萃分析

Indian Journal of Dental Research Pub Date : 2025-03-29 DOI: 10.4103/ijdr.ijdr_578_24

Anusa A Mohandoss, Rooban Thavarajah, Elizabeth Joshua, Umadevi K Rao

{"title":"Mitigation of Mouth Opening in Oral Submucous Fibrosis with Nutraceutical Products: A Network Meta-Analysis.","authors":"Anusa A Mohandoss, Rooban Thavarajah, Elizabeth Joshua, Umadevi K Rao","doi":"10.4103/ijdr.ijdr_578_24","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_578_24","url":null,"abstract":"Abstract: Oral submucous fibrosis (OSF) is associated with habitual use of areca nut. Several nonsurgical interventions for OSF have been used, with increasing predilection to try plant-based products. The objective of the present study is to investigate the efficacy of nutraceutical products (NPs) and other classes of nonsurgical interventions in OSF management using the network meta-analysis (NMA) approach. After registering with PROSPERO, the present study systematically searched for relevant studies in databases. PICO framework was used to identify studies relevant to evaluate the effectiveness of NPs and other classes of interventions. Standard NMA tools were used to assess the quality of the included studies and perform analysis. A total of 51 studies were included for final analysis with 53 trials. The primary outcome of identified studies was the mean difference (MD) in mouth opening (MO) expressed as mean (95% confidence interval). There were 16 interventions including placebo involving 3850 patients. The highest MD is 10.14 (4.38-15.89) with steroids with/without spreading factor (SSF) with ultrasonography (USG), followed by 9.87 (2.96-16.78) with SSF and NP-systemic and USG application, while the least is 1.43 (-4.31 to 7.18) SSF (8.04%). The probability of placebo being the most effective intervention in MO is the highest (93.91%), followed by exercise (81.50%), as evidenced by Surface Under the Cumulative Ranking Curve (SUCRA) and litmus rank-o-gram. This NMA results, within its limitation, showed that several NP outcomes are statistically superior to placebo in improving the MO, but as a class of drugs, none of the classes exhibited supremacy over others, especially to placebo. The result of this NMA indicates that none of classes of non-surgical treatment, especially NPs, have no distinct advantage in mitigation MO in OSF treatment.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse Effects of 'Two-by-Four Fixed Orthodontic Appliance' in Mixed Dentition Period - A Systematic Review. “二乘四固定正畸矫治器”在混合牙列期不良反应的系统回顾。

Indian Journal of Dental Research Pub Date : 2025-01-01 Epub Date: 2025-05-28 DOI: 10.4103/ijdr.ijdr_217_24

Mohammad Kamran Khan, Ramanandvignesh Pandiyan, Shakir Hussain Rather

{"title":"Adverse Effects of 'Two-by-Four Fixed Orthodontic Appliance' in Mixed Dentition Period - A Systematic Review.","authors":"Mohammad Kamran Khan, Ramanandvignesh Pandiyan, Shakir Hussain Rather","doi":"10.4103/ijdr.ijdr_217_24","DOIUrl":"10.4103/ijdr.ijdr_217_24","url":null,"abstract":"Abstract: Malocclusion is a global public dental health problem with higher prevalence and treatment needs. However, there is a perplexing literature regarding early orthodontic intervention in the mixed dentition stage. '2 × 4 orthodontic appliances' have been highlighted in the literature as versatile appliances for the effective correction of various malocclusions in children. However, dental clinicians and researchers should also have updated knowledge about the negative aspects of '2 × 4 orthodontic appliances', which are reported in the exiting literature. Hence, this systematic review aimed to find out the evidence about the adverse effects/complications of 2 × 4 orthodontic appliance therapy in mixed dentition phase of paediatric patients by extensively exploring and critically appraising the pertinent literature. This systematic review was performed as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Its protocol was registered in International Prospective Register of Systematic Reviews. Literature was searched comprehensively in six databases and also manually. After the screening of the records (n = 1234) as per the eligibility criteria, finally, nine (n = 5) articles were included and critically analysed using different Joanna Briggs Institute critical appraisal tools. Eligible studies including Randomized Controlled Trial (RCT) (n = 1), non-RCT (n = 2), retrospective study (n = 1), case-report (n = 1) published from 1999 to 2023 in which 82 patients with mean-age of 10-year, mostly with pseudo class-III malocclusion, anterior cross-bite and crowding treated using 2 x 4 appliance were found. The literature-based evidence related to the adverse effects of 2 × 4 orthodontic appliances was found to be inadequate in quantity, but majority was of high quality (low risk of bias). However, various negative aspects/complications of this particular fixed orthodontic therapy were reported by the included primary studies.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":"36 1","pages":"94-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Self-etching Adhesive Only Versus in Combination with Gluma Desensitizer for Preventing Post-composite Sensitivity - A Prospective Study. 自蚀刻胶与Gluma脱敏剂联合预防复合后敏感性的有效性——一项前瞻性研究。

Indian Journal of Dental Research Pub Date : 2025-01-01 Epub Date: 2025-05-28 DOI: 10.4103/ijdr.ijdr_586_23

Hemamalini Rath, Shilpa Mahapatra, Sri Priya Narayanan

{"title":"Effectiveness of Self-etching Adhesive Only Versus in Combination with Gluma Desensitizer for Preventing Post-composite Sensitivity - A Prospective Study.","authors":"Hemamalini Rath, Shilpa Mahapatra, Sri Priya Narayanan","doi":"10.4103/ijdr.ijdr_586_23","DOIUrl":"10.4103/ijdr.ijdr_586_23","url":null,"abstract":"Introduction: An increase in the incidence of postoperative sensitivity following composite restorations has become an everyday clinical problem. The aim of this study was to evaluate and compare the clinical effectiveness of a self-etching adhesive in combination with a dentin desensitizer (Gluma desensitizer), to a self-etching adhesive only, in preventing post-composite sensitivity immediately and over 30 days following a single topical application.Materials and methods: This clinical trial included 112 patients (206 teeth), who were randomized to receive self-etching adhesive in combination with Gluma desensitizer or a self-etching adhesive only. The included teeth were tested for tactile, air blast and cold stimuli, following which patients were asked to rate their sensitivity on an 11-point Numeric Rating Scale (NRS). The subjects were then assessed for post-composite sensitivity immediately after, as well as 1 week and 1 month following the treatment. Descriptive statistics were compared using t-test and Chi-square test. Intergroup comparisons of change in NRS scores to various stimuli were compared using the Mann-Whitney U test.Results: The baseline comparison of NRS scores to air, water and tactile stimuli did not reveal any statistically significant differences. The change in NRS scores post air blast, 1 week and 1 month, after the treatment for sensitivity, was observed to be significantly higher in the Gluma group compared to self-etching adhesive (P = 0.001).Conclusion: Subjects belonging to the Gluma desensitizer group reported a statistically significant reduction in postoperative sensitivity to air blast stimuli, following composite restoration, at both 1 week and 1 month follow-up.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":"36 1","pages":"32-36"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Zinc Oxide-Eugenol, Zinc Oxide-Propolis and Endoflas as an Obturating Materials in Primary Molar Pulpectomies - A Comparative Study. 氧化锌-丁香酚、氧化锌-蜂胶和内膜作为初级臼齿切开术封闭材料的比较研究。

Indian Journal of Dental Research Pub Date : 2025-01-01 Epub Date: 2025-05-28 DOI: 10.4103/ijdr.ijdr_76_23

Sunita Singh, Ashish Saxena, Vishal Khandelwal, Neha Verma, Arvind Jain

{"title":"Evaluation of Zinc Oxide-Eugenol, Zinc Oxide-Propolis and Endoflas as an Obturating Materials in Primary Molar Pulpectomies - A Comparative Study.","authors":"Sunita Singh, Ashish Saxena, Vishal Khandelwal, Neha Verma, Arvind Jain","doi":"10.4103/ijdr.ijdr_76_23","DOIUrl":"10.4103/ijdr.ijdr_76_23","url":null,"abstract":"Background: The goal of effective primary tooth infection treatment is to keep the child healthy. The need to find the optimum root canal paste, however, was driven by the complex morphology of primary root canals and the desire for shorter therapy sessions.Aims: To evaluate and compare the clinical and radiographic success of zinc oxide eugenol, Zinc oxide-Propolis, and endoflas as obturating materials in the pulpectomy of primary teeth at 3, 6 and 9 months of follow-up.Materials and methods: Pulpectomy of 60 nonvital primary molars was accomplished in 50 children aged 4-9 years. Teeth were randomly divided into three equal groups of 20 molars according to the type of root canal filling material. Pulpectomy was performed in a single or multiple visits depending on the condition of the tooth, and a stainless-steel crown was used for final restoration. Clinical and radiographic results were evaluated double-blindly at baseline (1 week), and at 3, 6 and 9 months, while radiographic results were evaluated at baseline (1 week), and at 6 and 9 months. Data were analysed using the Chi-square/Fisher's exact test, and the P value was set at 0.05.Results: Endoflas and a mixture of zinc oxide powder with Propolis showed promising results (100%), whereas zinc oxide eugenol showed a lower success rate than the other two materials (85%).Conclusions: Endoflas and a combination of zinc oxide powder with Propolis can be a promising material as an alternative to Zinc Oxide Eugenol for obturation in primary teeth.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":"36 1","pages":"54-59"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prosthetic Rehabilitation of Three Dentinogenesis Imperfecta Patients using Hobo Twin Stage Technique and Implant Supported Overdenture - A Case Report. Hobo双阶段技术联合种植支撑覆盖义齿修复牙体发育不全3例。

Indian Journal of Dental Research Pub Date : 2025-01-01 Epub Date: 2025-04-10 DOI: 10.4103/ijdr.ijdr_790_23

Amina, S Abirami, Geeta Rajput, Shaista Afroz, Shua Aftab

引用次数: 0

Prevalence of Radiographically Detectable Non-syndromic Dental Anomalies amongst Orthodontic Patients - A Retrospective Study. 在正畸患者中放射可检测的非综合征性牙齿异常的患病率-一项回顾性研究。

Indian Journal of Dental Research Pub Date : 2025-01-01 Epub Date: 2025-05-28 DOI: 10.4103/ijdr.ijdr_589_22

Rahul Koul, Sanjeev Datana, Saugat Ray

{"title":"Prevalence of Radiographically Detectable Non-syndromic Dental Anomalies amongst Orthodontic Patients - A Retrospective Study.","authors":"Rahul Koul, Sanjeev Datana, Saugat Ray","doi":"10.4103/ijdr.ijdr_589_22","DOIUrl":"10.4103/ijdr.ijdr_589_22","url":null,"abstract":"Introduction: Developmental dental anomalies are variations from expected clinical appearance, shape, size, color, contour, number, eruption pattern, and degree of tooth development. Early diagnosis of such anomalies helps formulate a treatment plan and provide optimal dental care.Materials and method: Present study was a retrospective study designed to identify and analyze non-syndromic developmental dental anomalies amongst children and adolescents aged 9 to ≤19 years of Indian origin belonging to both genders who reported for orthodontic treatment. The data were subjected to descriptive and analytical statistics; Pearson's Chi-square test, and Spearman rank correlation coefficient were used.Results: In 1017 subjects (559 male, 458 female), a total of 569 individuals (277 male, 292 female) and 853 teeth had anomalies. The most common anomalies in the study sample were impacted with teeth (24.5%), dilaceration (10.4%), and hypodontia (6.8%). The maxillary canine was the most commonly involved in any form of anomaly. Approximately, 32.54% (n = 331) of subjects showed only one tooth anomaly, 26.74% (n = 272) of participants showed anomalies in two teeth, whereas 7.6% (n = 77) of patients showed anomalies in three or more teeth.Conclusion: Most commonly observed anomaly in the present study was impacted teeth (24.5%). The maxillary canine was the most commonly involved tooth in any form of anomaly.","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":"36 1","pages":"69-74"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0