Indian Journal of Dental Research最新文献

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Salivary Calprotectin Levels and Bone Mineral Density in Post-Menopausal Women With and Without Chronic Periodontitis - An Evaluative Study. 患有和未患有慢性牙周炎的绝经后妇女的唾液钙粘蛋白水平和骨矿物质密度--一项评估性研究。
Indian Journal of Dental Research Pub Date : 2024-09-14 DOI: 10.4103/ijdr.ijdr_522_21
J Pavithra, Amitha Ramesh, Biju Thomas, N Suchetha Kumari, K P Sharmila
{"title":"Salivary Calprotectin Levels and Bone Mineral Density in Post-Menopausal Women With and Without Chronic Periodontitis - An Evaluative Study.","authors":"J Pavithra, Amitha Ramesh, Biju Thomas, N Suchetha Kumari, K P Sharmila","doi":"10.4103/ijdr.ijdr_522_21","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_522_21","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause is a normal developmental stage in a woman's life marking the permanent cessation of menstruation. Periodontitis and osteoporosis are noteworthy health concerns in post-menopausal women. Calprotectin is an inflammatory biomarker for precise diagnosis of periodontal disease.</p><p><strong>Materials and methods: </strong>This study was performed to evaluate the variations in salivary calprotectin levels and bone mineral density in post-menopausal women with and without chronic periodontitis. The study included 24 post-menopausal women aged 45-57 years and was divided into group 1 (12 post-menopausal women without chronic periodontitis) and group 2 (12 post-menopausal women with chronic periodontitis). Unstimulated salivary samples, panoramic radiographs and clinical examination were performed.</p><p><strong>Results: </strong>The collected samples were combined with CALPRO antibody with horseradish peroxide (HRP) that results in the formation of antigen-antibody complex. Tetramethylbenzidine (TMB) solution was added that turned blue. Colour change was measured at 450nm. A human ELISA kit was used. Data collected were sent for statistical analysis.</p><p><strong>Discussion: </strong>There was a statistically significant difference in salivary calprotectin levels between groups 1 and 2 (P = 0.016) and no statistical difference in mean bone mineral density levels between the two groups (P = 0.235). A positive correlation was seen between salivary calprotectin levels and bone mineral density in group 2 (P = 0.013).</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Caries Experience on the Oral Health-Related Quality of Life of Pre-school Children and their Families in an Indian City - An Evaluative Study. 龋齿经历对印度城市学龄前儿童及其家庭与口腔健康相关的生活质量的影响--一项评估性研究。
Indian Journal of Dental Research Pub Date : 2024-09-14 DOI: 10.4103/ijdr.ijdr_928_21
Neha Patyal, Hemamalini Rath, Shilpa Mahapatra
{"title":"Impact of Caries Experience on the Oral Health-Related Quality of Life of Pre-school Children and their Families in an Indian City - An Evaluative Study.","authors":"Neha Patyal, Hemamalini Rath, Shilpa Mahapatra","doi":"10.4103/ijdr.ijdr_928_21","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_928_21","url":null,"abstract":"<p><strong>Background: </strong>The presence of dental caries may have a negative impact on well-being of children and their parents, causing pain and discomfort, leading to poor oral health-related quality of life (OHRQoL) in them. The objective of this study was to evaluate the impact of different levels of caries experience on the OHRQoL of pre-school children and their families in Odisha, assessed using Odia version of Early Childhood Oral Health Impact Scale (Od-ECOHIS).</p><p><strong>Methodology: </strong>A cross-sectional survey was carried out on a sample of 369 pre-school children using Od-ECOHIS. Dental caries was recorded using International Caries Detection and Assessment System (ICDAS) index.</p><p><strong>Result: </strong>The total score of ECOHIS ranged from 0 to 42 with a mean of 2.4 (±5.3) and a median score of 0. The items bearing high mean scores in the child impact section were related to \"pain\", \"difficulty in drinking hot or cold beverages\", \"difficulty in eating some food\", and \"irritable or frustrated\". Though half of children (50.4%) had cavitated carious lesions, the prevalence of negative impact was 30.6%. Compared to the child being caries-free, the expected count of total Od-ECOHIS score increased by 1.54 times if the child had white spot lesion and 1.94 times if the child had a cavitated lesion.</p><p><strong>Conclusion: </strong>Presence of dental carious lesions has a significant impact on OHRQoL of pre-school children and their families measured by using Od-ECOHIS even after adjusting for SES and caregivers' perception of their children's oral health.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Lip Repositioning in Search of Aesthetics - A Case Series. 追求美感的唇部手术复位--病例系列。
Indian Journal of Dental Research Pub Date : 2024-09-14 DOI: 10.4103/ijdr.ijdr_835_23
Sk Aziz Ikbal, Zeba R Siddiqui, Siddhartha Dutta, Tasneem Fatima, Roopanshi Mehrotra, Surendra K Yadav
{"title":"Surgical Lip Repositioning in Search of Aesthetics - A Case Series.","authors":"Sk Aziz Ikbal, Zeba R Siddiqui, Siddhartha Dutta, Tasneem Fatima, Roopanshi Mehrotra, Surendra K Yadav","doi":"10.4103/ijdr.ijdr_835_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_835_23","url":null,"abstract":"<p><strong>Introduction: </strong>The gummy smile (GS) or excessive gum visibility (EGV) is an aesthetic concern that affects an individual's attractiveness and personality.</p><p><strong>Treatment planning: </strong>Lip Repositioning surgery (LRP) is a less invasive surgery that can be attributed to treating EGV due to hypermobile lip muscles or mild-to-moderate vertical maxillary excess (VME). Three patients went through LRP surgery by stripping overlying mucosa from the buccal vestibule, followed by suturing the lip mucosa to the mucogingival junction (MGJ), creating shallow vestibule and restricted muscle pull and reducing gingival visibility (GV) during a smile.</p><p><strong>Followup: </strong>Three months of follow-up showed a satisfactory result with 3.67 ± 0.58 mm mean reduction in GV.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Andrographis paniculata Herbal Extract on Cytotoxicity, Proliferation and Osteogenic/Odontogenic Differentiation of Human Dental Pulp Stem Cells: An In Vitro Study. 穿心莲草本提取物对人牙髓干细胞细胞毒性、增殖和成骨/成牙分化的影响:体外研究。
Indian Journal of Dental Research Pub Date : 2024-09-14 DOI: 10.4103/ijdr.ijdr_907_22
Savitha B Naik, N Kiran Kumar, P Annie Swathisha, Biji Brigit, H S Preetham, Chella S Karumaran
{"title":"Effect of Andrographis paniculata Herbal Extract on Cytotoxicity, Proliferation and Osteogenic/Odontogenic Differentiation of Human Dental Pulp Stem Cells: An In Vitro Study.","authors":"Savitha B Naik, N Kiran Kumar, P Annie Swathisha, Biji Brigit, H S Preetham, Chella S Karumaran","doi":"10.4103/ijdr.ijdr_907_22","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_907_22","url":null,"abstract":"<p><strong>Background: </strong>Research has been conducted to assess the regenerative potential of dental pulp stem cells (DPSCs) following pretreatment of stem cells with certain molecules, bioactive compounds, plant extract and physical stimulation. Andrographis paniculata (AP) herbal extract with important medicinal properties is proven to have a preosteogenic effect on osteoblasts.</p><p><strong>Aim: </strong>This study aimed to determine the effect of various concentrations of AP extract on the cytotoxicity and osteogenic and odontogenic potential of DPSCs.</p><p><strong>Methods and material: </strong>Dental pulp stem cells were subjected to treatment with various concentrations of AP herbal extract (7 ug/ml, 5.2 ug/ml, 3.5 ug/ml, 1.7 ug/ml and 0.8 ug/ml), following which the cells were subjected to tests-3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) analysis for cytotoxicity and real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test for expression of genes (bone morphogenetic protein (BMP), osteocalcin (OCN), dentin sialophosphoprotein (DSPP) and alkaline phosphatase (ALP)).</p><p><strong>Results: </strong>AP extract at concentration of 0.8 ug/ml-5.2 ug/ml had no cytotoxicity supporting cell growth. 3.5 ug/ml showed significant upregulation of genes on the third day.</p><p><strong>Conclusion: </strong>AP, a commonly occurring medicinal plant through its effect on DPSCs, could serve as an effective pretreatment modality for cell-based regenerative therapy and vital pulp therapy.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Stresses Generated with Two Different Self-Ligating Orthodontic Bracket Systems - A Finite Element Analysis. 评估两种不同的自锁式正畸托槽系统产生的应力--有限元分析。
Indian Journal of Dental Research Pub Date : 2024-09-14 DOI: 10.4103/ijdr.ijdr_937_23
Mohit Awaradi, Roshan M Sagarkar, Prashantha G Shivamurthy, Silju Mathew, Sharanya Sabrish, Nirajita Bhaduri
{"title":"Evaluation of Stresses Generated with Two Different Self-Ligating Orthodontic Bracket Systems - A Finite Element Analysis.","authors":"Mohit Awaradi, Roshan M Sagarkar, Prashantha G Shivamurthy, Silju Mathew, Sharanya Sabrish, Nirajita Bhaduri","doi":"10.4103/ijdr.ijdr_937_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_937_23","url":null,"abstract":"<p><strong>Aim: </strong>To determine stresses generated in the posterior teeth region by two different self-ligating systems, 3M Unitek SmartClip and Damon Q Self-ligating brackets, using the finite element method (FEM).</p><p><strong>Methodology: </strong>Computed tomography (CT) scan of maxilla was taken using Mimics software, and the Dicom data were imported into Hypermesh 13.0 software to convert it into a geometric model and then into FEM. Physical models of both the brackets were constructed and positioned on the teeth. Post archwire modeling, contact is defined between the bracket slot and 0.014\" NiTi arch wire. The final assembled model was exported to ANSYS 12.1 for analysis, and 60 grams of load was applied at the ends of the arch wire.</p><p><strong>Results: </strong>On using 0.014\" CuNiTi in both the bracket systems, stresses generated on the root surface were found to be maximum on the first molar region, followed by the first premolar, second molar, canine, and second premolar regions. Comparison between the two bracket systems showed differences in the stresses generated, where higher stresses were generated at all regions in the Damon Q bracket system, except the inter-second premolar region.</p><p><strong>Conclusion: </strong>Maximum stresses were observed with the 3M Unitek SmartClip bracket system at the second premolar cervical region when compared to the Damon Q system. In both the cortical bone and cancellous bone, maximum stresses were observed at the second premolar cervical in the Damon Q bracket system region.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trichofolliculoma - A Case Report. 毛囊角化瘤--病例报告。
Indian Journal of Dental Research Pub Date : 2024-08-22 DOI: 10.4103/ijdr.ijdr_6_22
G Suganya, Sahana Srinath, J Chandrakala, Satish T Yadav
{"title":"Trichofolliculoma - A Case Report.","authors":"G Suganya, Sahana Srinath, J Chandrakala, Satish T Yadav","doi":"10.4103/ijdr.ijdr_6_22","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_6_22","url":null,"abstract":"<p><strong>Abstract: </strong>Trichofolliculoma is a rare benign, hamartomatous adnexal tumour of the skin. Aetiology seems to be unclear. It is usually seen in adults, with no gender predilection. The most commonly involved sites are the face and scalp. It appears as a papule or nodule with small protruding hairs, which is a classic feature of the tumour. It has unique diagnostic and histopathological features that help in making a definitive diagnosis. Here, we report an exemplary case of an adult male patient aged 45 years with a gradual progressive diffuse swelling on the left side of the face for 1.5 years. Clinically, it was diagnosed as a sebaceous cyst, but after the biopsy histopathological evaluation was performed, and the diagnosis was confirmed as trichofolliculoma.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of Various Antioxidants on the Shear Bond Strength of Composite Resin to Bleached Enamel - An In Vitro Study. 各种抗氧化剂对复合树脂与漂白珐琅质剪切粘接强度的比较评估--一项体外研究。
Indian Journal of Dental Research Pub Date : 2024-08-22 DOI: 10.4103/ijdr.ijdr_893_23
N Bhasker, Pachalla Mayuri Sailaja, Shiva Sandeep, J Krishnaveni
{"title":"Comparative Evaluation of Various Antioxidants on the Shear Bond Strength of Composite Resin to Bleached Enamel - An In Vitro Study.","authors":"N Bhasker, Pachalla Mayuri Sailaja, Shiva Sandeep, J Krishnaveni","doi":"10.4103/ijdr.ijdr_893_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_893_23","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and compare the effect of various antioxidants on the shear bond strength of composite resin to bleached enamel.</p><p><strong>Materials and methods: </strong>Labial enamel surfaces of 90 extracted human maxillary central incisors were randomly divided into five groups based on the antioxidant used as follows: Group I (n = 20): Bleaching with 40% hydrogen peroxide gel for 10 min, without the use of an antioxidant; Group II (n = 20): Bleaching followed by the use of 10% sodium ascorbate solution; Group III (n = 20): Bleaching followed by the use of 5% grape seed extract solution; Group IV (n=20): Bleaching followed by the use of 5% pine bark extract solution; and Group V (n=20): Control group in which no bleaching was done. Groups I-IV were further subdivided into two subgroups of 10 teeth each, whether the antioxidant application and composite build-up was done immediately (subgroup A) or after 2 weeks of postbleaching (subgroup B). Shear bond strength of the specimens was tested under a universal testing machine.</p><p><strong>Results: </strong>One-way analysis of variance followed by Mann-Tukey posthoc multiple comparison test was used to analyse the data. The level of significance was established at P < 0.05.</p><p><strong>Conclusion: </strong>Within the limitations of this study, it was observed that the use of antioxidants effectively reversed the compromised bond strength of bleached enamel. Among the antioxidants, 5% pine bark extract application after bleaching showed better bond strength.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of the Efficacy of ProTaper & Mtwo Rotary Retreatment System and Conventional Hand H-files for Removal of Gutta-percha from Root Canal - A Stereomicroscopic Study. ProTaper & Mtwo 旋转再治疗系统与传统手工 H 型锉去除根管中水门汀胶的功效比较评估--一项立体显微镜研究。
Indian Journal of Dental Research Pub Date : 2024-08-22 DOI: 10.4103/ijdr.ijdr_145_23
Krutika D Chudasama, Shraddha Chokshi, Zarana Sanghvi, Nishit Patel, Naman Vaidya, Deesha Chhaya
{"title":"Comparative Evaluation of the Efficacy of ProTaper & Mtwo Rotary Retreatment System and Conventional Hand H-files for Removal of Gutta-percha from Root Canal - A Stereomicroscopic Study.","authors":"Krutika D Chudasama, Shraddha Chokshi, Zarana Sanghvi, Nishit Patel, Naman Vaidya, Deesha Chhaya","doi":"10.4103/ijdr.ijdr_145_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_145_23","url":null,"abstract":"<p><strong>Background: </strong>Root canal retreatment aims to eliminate or substantially reduce the microbial load from the root canal and removal of previous root filling materials is the primary goal of nonsurgical retreatment.</p><p><strong>Aim: </strong>To comparatively evaluate the effectiveness of ProTaper retreatment files, Mtwo retreatment files, and Hedstrom files along with Gates Glidden (GG) Drill by using a stereomicroscope for the detection of remaining gutta-percha after root canal retreatment using a stereomicroscope.</p><p><strong>Materials and methods: </strong>Forty-five test samples were divided into three experimental groups (15 samples each), such as Group A-ProTaper retreatment files; Group B-Mtwo retreatment files; Group C-Hedstrom files along with Gates Glidden Drill. After routine endodontic treatment in the test samples, gutta-percha was removed from the test samples as per the division of different retreatment file systems. Further, test samples were divided longitudinally and were evaluated under the stereomicroscope. Stereomicroscopic images were captured and analysed under Image Analyser Software-Image J.</p><p><strong>Statistical analysis: </strong>One-way ANOVA test was used for comparison of gutta-percha removal between the groups and Tukey's post hoc test was used for pairwise comparisons.</p><p><strong>Results: </strong>The least remaining filling material was seen in specimens retreated with the ProTaper universal system. The highest remaining filling material was seen in specimens retreated with Hedstrom file with Gates Glidden Drill.</p><p><strong>Conclusion: </strong>All experimental test techniques left gutta-percha remnants within the root canal. ProTaper universal rotary retreatment system proved to be an efficient method of removing gutta-percha and left relatively less volume in comparison with other test systems.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Periodontal Therapy on Rheumatoid Disease Activity in Patients on Anti-Rheumatoid Drugs - A Prospective Study. 牙周治疗对服用抗类风湿药物患者类风湿病活动性的影响--一项前瞻性研究。
Indian Journal of Dental Research Pub Date : 2024-08-22 DOI: 10.4103/ijdr.ijdr_535_23
Arunachalam Kaveri, Velayudham Rajendran, Tukaram Kshirsagar Jaishree, Krishnamoorthy Malathi, Mohanasundaram Kavitha
{"title":"Effect of Periodontal Therapy on Rheumatoid Disease Activity in Patients on Anti-Rheumatoid Drugs - A Prospective Study.","authors":"Arunachalam Kaveri, Velayudham Rajendran, Tukaram Kshirsagar Jaishree, Krishnamoorthy Malathi, Mohanasundaram Kavitha","doi":"10.4103/ijdr.ijdr_535_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_535_23","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this clinical trial rheumatoid arthritis-chronic periodontitis (RA-CP) is to assess the effect of non-surgical periodontal therapy in RA patients.</p><p><strong>Materials and methods: </strong>Sixty RA patients taking disease-modifying anti-rheumatoid drugs (DMARD) with CP were selected from the Institute of Rheumatology, Madras Medical College, randomised into the intervention group (IG) and control group (CG). IG received non-surgical periodontal therapy after the screening visit, but CG did not receive treatment until the 3 months study period. Periodontal parameters were recorded at baseline and after 3 months for both groups. Rheumatoid Disease activity (RD activity) was assessed using disease activity score (DAS28), inclusive of tender joints count (TJC), swollen joints count (SJC), visual analog scale (VAS), and erythrocyte sedimentation rate (ESR) for both groups at baseline and after 3 months.</p><p><strong>Results: </strong>At the end of 3 months, IG had significant reduction in RA parameters such as tender joints count (0.0005), swollen joints count (0.0005), ESR (0.003), VAS score (0.0005), and DAS28 values (0.0005) compared to CG. Periodontal parameters at the end of 3 months were also significantly reduced in IG than in CG.</p><p><strong>Conclusion: </strong>Non-surgical periodontal therapy might have reduced the burden of systemic inflammatory markers, thus reducing severity of RA in IG. Reduction in tenderness and swelling of joints in the upper arm might have enabled the patients in IG to perform better oral hygiene maintenance procedures.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Quantitative Assessment of Apoptotic Index with Varying Histological Degree of Dysplasia and Squamous Cell Carcinoma of Oral Cavity - A Light Microscopic Study. 不同组织学程度的口腔增生异常和鳞状细胞癌凋亡指数的定量评估--一项光学显微镜研究。
Indian Journal of Dental Research Pub Date : 2024-08-22 DOI: 10.4103/ijdr.ijdr_382_23
Chitrapriya Saxena, Vijay Wadhwan, Vijay Kumar, Aparna Singh, Siddharth Anand, Asib Ahmad
{"title":"A Quantitative Assessment of Apoptotic Index with Varying Histological Degree of Dysplasia and Squamous Cell Carcinoma of Oral Cavity - A Light Microscopic Study.","authors":"Chitrapriya Saxena, Vijay Wadhwan, Vijay Kumar, Aparna Singh, Siddharth Anand, Asib Ahmad","doi":"10.4103/ijdr.ijdr_382_23","DOIUrl":"https://doi.org/10.4103/ijdr.ijdr_382_23","url":null,"abstract":"<p><strong>Aim and objective: </strong>The aim of the present study was to quantitatively assess the apoptotic index at a light microscopic level in hyperkeratosis with varying histological degrees of dysplasia and different grades of oral squamous cell carcinoma (OSCC) and its correlation with prognostic significance.</p><p><strong>Study design: </strong>The study included the histo-pathologically diagnosed cases of hyperkeratosis with varying degrees of dysplasia and different grades of OSCC, which were retrieved from the archives of the department, and clinical details were retrieved from the case records of the patients. The sample size consisted of 80 biopsied cases, divided into seven groups of 10 experimental cases and one group of 10 cases of normal mucosa as a control group.</p><p><strong>Results: </strong>The age range of 50-59 shows maximum patients of hyperkeratosis with varying degrees of dysplasia and OSCC. Maximum apoptotic bodies were seen in cases of severe dysplasia and well-differentiated cases of OSCC. There was an observational difference noticed in apoptotic bodies between the patients who had less than 1-year disease-free survival rate.</p><p><strong>Conclusions: </strong>The apoptotic cells are being seen using routine light microscopy techniques with hematoxylin and eosin staining. In different grades of squamous cell carcinoma, a decrease in the apoptotic count was noticed from well-differentiated squamous cell carcinoma toward poorly differentiated squamous cell carcinoma cases. Increased mean apoptotic bodies were observed in patients showing less than 1 year of survival.</p>","PeriodicalId":13311,"journal":{"name":"Indian Journal of Dental Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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