Frontiers in Veterinary Science最新文献

{"title":"Biosecurity implementation in poultry farms across Europe and neighboring countries: a systematic review.","authors":"Ronald Vougat Ngom, Marta Leite, Giuditta Tilli, Andrea Laconi, Qamer Mahmood, Jasna Prodanov-Radulović, Alberto Allepuz, Ilias Chantziaras, Alessandra Piccirillo","doi":"10.3389/fvets.2025.1653543","DOIUrl":"10.3389/fvets.2025.1653543","url":null,"abstract":"<p><strong>Introduction: </strong>Modern poultry production systems inherently concentrate large numbers of birds, which also increases the risk and potential impact of disease outbreaks. Biosecurity is widely recognized as the most important tool for reducing the risk of disease introduction, establishment, and spread to, within, and from an animal population. Thus, effective biosecurity is essential for sustainable poultry production, and assessing its implementation represents a crucial step. This systematic review aimed to evaluate biosecurity implementation in poultry farms across European and neighboring countries.</p><p><strong>Methods: </strong>The Cochrane Handbook and PRISMA 2020 guidelines were followed to perform the systematic review.</p><p><strong>Results: </strong>Of the 1,515 articles retrieved from four databases, only 44 met the inclusion criteria and 16 provided usable data for assessing biosecurity implementation. Despite relatively broad geographical coverage, including eight multi-country studies involving 36 national assessments, the distribution of studies was uneven. Moreover, most studies (77%) were pathogen- or disease-specific (e.g., <i>Campylobacter</i> spp., avian influenza, etc.) and focused on a single poultry species, primarily broilers (55%), while assessments involving minor poultry species were rare. There was also marked variability in the methods used to assess biosecurity, and the level of biosecurity implementation differed significantly across countries. Based on descriptive evaluations, 58% of farms implemented all the biosecurity measures assessed. According to scoring-based assessments, the overall average biosecurity score was 66.9 out of 100. The most frequently implemented measures were those related to infrastructure and control of biological vectors, disease management, and purchase of one-day-old chicks.</p><p><strong>Discussion: </strong>The heterogeneity of results, driven by differences in study design, poultry species, production systems, and methodological approach, highlights the complexity of evaluating biosecurity across diverse national contexts. This variability may reflect differences in epidemiological conditions, research funding, and national priorities. Although this review focused solely on primary research studies, the findings underscore the need to promote cross-country collaboration to enhance knowledge sharing and data harmonization.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1653543"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The expanding role of microRNAs in the biology and control of veterinary parasitic nematodes.","authors":"Vishnu Manikantan, Andrea Pires Dos Santos, Sriveny Dangoudoubiyam","doi":"10.3389/fvets.2025.1668932","DOIUrl":"10.3389/fvets.2025.1668932","url":null,"abstract":"<p><p>Parasitic nematodes threaten animal health globally, contributing to substantial losses in livestock productivity and posing zoonotic risks through infections in companion animals. There is a growing concern over widespread resistance to anthelmintic drugs, necessitating new molecular approaches for parasite control. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression and have emerged as key modulators of nematode development, growth, stage transitions, host-pathogen interactions, and parasite survival. Certain miRNAs are expressed in a stage- and sex-specific manner, and many are selectively secreted via extracellular vesicles, enabling direct interactions with the host. The detection of worm-derived miRNAs in blood of an infected host highlights their potential as early diagnostic biomarkers for nematode infections. Emerging evidence links miRNAs to anthelmintic resistance. This review provides an overview of miRNA biogenesis, gene regulation mechanisms, and current miRNA discovery and experimental validation approaches. Importantly, it highlights species-specific advances in miRNA research in parasitic nematode infections of veterinary importance, emphasizing their roles in parasite biology, immune modulation, and drug resistance.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1668932"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adiponectin receptor agonist reduces broiler hepatic lipid deposition.","authors":"Wenhao Tan, Kunyu Jiang, Yuhan Zhang, Hang Gao, Xingyi Tang, Sha Jiang","doi":"10.3389/fvets.2025.1667501","DOIUrl":"10.3389/fvets.2025.1667501","url":null,"abstract":"<p><p>To investigate the effects of AdipoRon on fatty liver syndrome (FLS) in chicken, we used a corticosterone (CORT)-induced fatty liver model in Cobb broilers <i>in vivo</i> and fat emulsion-induced model in Leghorn male hepatoma cells (LMH) <i>in vitro</i>. In the <i>in vivo</i> study, eighteen 33-day-old male Cobb broilers were randomly assigned to three groups: control group (CONT, vehicle), corticosterone-treated group (CORT, 4 mg/kg), and corticosterone with AdipoRon-treated group (CORT-AR, 4 mg/kg and 0.2 mg/kg, 1 time/1 day) for 5 days. The results showed AdipoRon reduced CORT-induced increase in liver crude fat content (<i>p</i> < 0.05), increased protein expressions of peroxisome proliferator-activated receptor <i>α</i> (PPARα) (<i>p</i> < 0.05) and adiponectin (ADPN) (<i>p</i> < 0.05), and suppressed the protein expressions of Acetyl-CoA carboxylase 1 (ACC) (<i>p</i> < 0.05) and phosphorylated c-Jun N-terminal kinase 1 (p-JNK1) (<i>p</i> < 0.05) in the liver. In the <i>in vitro</i> study, LMH cells were divided into control (CN), fat emulsion (FE, 10%), and FE + AdipoRon (4 μM) group (FE-AR). AdipoRon reduced FE-induced lipid accumulation (<i>p</i> < 0.05), decreased the protein expression of ACC and tumor necrosis factor-alpha (TNF-<i>α</i>), and enhanced PPARα, the phosphorylation of adenosine 5'-monophosphate-activated protein kinase (AMPK), and carnitine palmitoyl transferase 1 (CPT-1) (<i>p</i> < 0.05). In conclusion, AdipoRon effectively reduces hepatic lipid deposition in CORT-induced FLS broilers, likely through PPARα activation and inhibition of lipid synthesis via ACC downregulation.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1667501"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From burnout to engagement: enhancing the wellbeing and performance of conservationists.","authors":"Thirza A C Loffeld, Simon A Black, Tatyana Humle","doi":"10.3389/fvets.2025.1567931","DOIUrl":"10.3389/fvets.2025.1567931","url":null,"abstract":"<p><p>The purpose of this study was to explore how job characteristics relate to multiple dimensions of work performance in conservation professionals, with burnout and work engagement as mediating factors. A global sample of 561 conservation professionals across 98 countries completed an online survey. Using the Job Demands-Resources (JD-R) model and structural equation modelling, we found that participants with more frequent access to job resources (e.g., autonomy in work methods, social support at work, and availability of useful information), reported higher levels of work engagement. In turn, greater work engagement, characterised by vigour, dedication and absorption, was associated with increased task performance (e.g., working efficiently, managing time effectively) and contextual performance (e.g., taking initiative, creative problem-solving). Contrary to previous research in other sectors, job demands did not show a direct relationship to burnout in this conservation sample. However, higher burnout was linked to lower task performance. Moreover, burnout mediated the relationship between job resources and task performance: greater job resources were associated with lower levels of burnout, which in turn was associated with higher task performance. Our findings underscore the importance for both individual professionals and conservation organisations to enhance job resources and work engagement, given their positive relationships with multiple work performance indicators. These results may guide efforts to identify which perceived job characteristics are most likely to enhance performance, either directly or indirectly, through increased work engagement or reduced burnout. Furthermore, when organisations observe a decline across various performance indicators, this may signal a need to strengthen support for staff wellbeing and motivation. This study is the first to quantitatively examine relationships between job characteristics and multiple dimensions of work performance in a global sample of conservation professionals, highlighting the JD-R model's relevance to conservation.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1567931"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed tomographic signs of hyoid apparatus disease in 165 horses.","authors":"Bettina Hartl, Carina Strohmayer, Yasamin Vali, Manolis Lyrakis, Sibylle M Kneissl","doi":"10.3389/fvets.2025.1631185","DOIUrl":"10.3389/fvets.2025.1631185","url":null,"abstract":"<p><strong>Introduction: </strong>Horses with hyoid bone disease may present with clinical symptoms such as exercise intolerance, resistance to ridden work, anorexia, or headshaking. This study aims to describe the computed tomographic (CT) signs and prevalence of hyoid disease and to evaluate their association with other CT changes of the head.</p><p><strong>Methods: </strong>In this study, four investigators conducted a retrospective analysis of their findings after reviewing the medical records of 200 horses that had undergone CT scans between 2009 and 2019. A total of 32 parameters were analyzed, and associations were evaluated between those parameters and the effects of age, weight, and use on the development of hyoid bone disease.</p><p><strong>Results: </strong>The temporohyoid joint (THJ) exhibited the most common CT signs, with 52% of cases showing marginal exostosis of the temporal bone, 44.4% displaying osteophytes of the proximal stylohyoid, and 40.2% demonstrating reduced tympanohyoid on the examined sides. The most frequently observed CT signs at the styloceratohyoid/epiceratohyoid joint were marginal exostosis of the distal stylohyoid, identified in 29.0% of the examined sides, and osteoproliferative changes of the proximal ceratohyoid, present in 16.5% of the examined sides. CT signs of disease were rarely found at the ceratobasihyoid joint. Pathological CT signs of the ceratobasihyoid joint were associated with those of the styloceratohyoid/epiceratohyoid joint, and disease in this joint was associated with those of the THJ. The findings of the present study revealed an age-related effect on the occurrence of marginal exostosis and osseous cyst-like lesions (OCLLs) of the temporal bone, as well as on OCLLs and osteophytes of the proximal stylohyoid, and on the thickening of the THJ, and a reduction in the tympanohyoid. Age was also found to influence the incidence of the two styloceratohyoid/epiceratohyoid joint CT signs: marginal exostosis of the distal stylohyoid and osteoproliferative changes at the proximal ceratohyoid. The weight and use of the horses did not affect the occurrence of the evaluated changes.</p><p><strong>Conclusion: </strong>CT signs of disease of the hyoid apparatus are common and should be considered as part of the differential diagnosis when examining a horse with poor performance, riding complaints, or headshaking.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1631185"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk assessment of African swine fever transmission by spray-dried porcine plasma in piglet feed and the effect of UV irradiation treatment as an additional safety step.","authors":"Clazien J de Vos, Lourens Heres, Aldo Dekker, Manon Swanenburg, W Meindert Pelser, Jacob Post, Marcel M Hulst","doi":"10.3389/fvets.2025.1463720","DOIUrl":"10.3389/fvets.2025.1463720","url":null,"abstract":"<p><p>The increase of African swine fever (ASF) outbreaks worldwide has raised concerns about the feeding of spray-dried porcine plasma (SDPP) to pigs. The processing of blood into SDPP should thus guarantee sufficient inactivation of ASF virus (ASFV) to render a safe product. The objective of this study was to evaluate (i) the required level of inactivation if blood of ASF-infected pigs would be processed into SDPP and fed to piglets, and (ii) the additional safety achieved if UV treatment is applied to plasma before spray-drying. A quantitative microbial risk assessment (QMRA) model was built to assess the infection probability (<i>P_inf</i> ) of weaned piglets fed with SDPP produced from blood collected from a single ASF-infected herd. The inactivation of ASFV by UV treatment was quantified using a mobile, laboratory-scale \"Cold Pasteurization\" apparatus (Lyras inc, Aalborg, Denmark). Porcine plasma spiked with blood collected from pigs experimentally infected with ASFV was irradiated with different doses of UV-C and the log₁₀ reduction factor (LRF) calculated. An average LRF of 2.2 was achieved by the highest dose of UV-C irradiation applied (~137 Joule/m²). QMRA model results indicate that an LRF of 5 needs to be achieved during processing to arrive at a median value of <i>P_inf</i> < 0.01, i.e., less than 1 out of 100 ASF-infected batches resulting in new infections. With an LRF of 8, also the 95th percentile value of <i>P_inf</i> is < 0.01. These results were compared to reported LRF values of spray-drying and dry storage of SDPP, which varied between 5.2 and 11.1. Applying UV-C irradiation as an additional step in SDPP production thus provides extra safety guarantees as the combined inactivation levels of spray-drying, dry storage and UV treatment are likely to result in an overall LRF ≥ 8, implying a very low risk of new ASF infections (median <i>P_inf</i> 7.3 × 10^-6; 95th percentile 1.6 × 10^-3). The QMRA model did not account for the probability that ASF-infected pigs are unintendedly processed into SDPP. This probability is low if SDPP is not sourced from pigs in ASF-infected areas, therewith further reducing the ASF infection risk of SDPP.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1463720"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peritumoral MRI findings and brain herniations in epileptic dogs with prosencephalic brain tumors: a multicentre retrospective study.","authors":"Marco Tabbì, Domenico Fugazzotto, Chiara Caterino, Simone Minniti, Valeria Toneatti, Giuseppe Barillaro, Simone Minato, Claudia Giannetto, Gerardo Fatone, Francesco Macrì","doi":"10.3389/fvets.2025.1661131","DOIUrl":"10.3389/fvets.2025.1661131","url":null,"abstract":"<p><p>Prosencephalic brain tumors (PBTs) are frequently associated with epileptic seizure in dogs, yet the incidence and characteristics of brain herniations (BHs) in this context remain poorly described. This multicentre retrospective study aimed to evaluate the incidence and distribution of BHs and other associated MRI findings in 80 dogs presenting with epileptic seizures secondary to PBTs. MRI studies were assessed for peritumoral edema, lateral ventricular compression, midline shift (MS), subfalcine herniation (SH), caudal transtentorial herniation (CTH), foramen magnum herniation (FMH), and displacement of the quadrigeminal lamina (DQL). Peritumoral edema and lateral ventricular compression were observed in 85 and 77.5% of cases, respectively. MS was observed in 87.5% of cases. SH and CTH were the most common BHs, present in over 75 and 31% of cases, respectively. DQL was observed in 57% of cases, including dogs with tumors anatomically distant from the midbrain. Although tumor volume did not significantly differ between groups, larger lesions were positively correlated with the presence of edema, lateral ventricular compression and laminar displacement. These findings demonstrate that MRI features reflecting mass effect-particularly peritumoral edema, MS, and specific types of BHs-are highly prevalent in dogs with seizure-associated PBTs and may contribute to epileptic seizures generation. The MRI features identified in this study may have prognostic value for potential epileptic seizures development, and should therefore be considered during the clinical evaluation of affected dogs.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1661131"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mouse models for enteral and parenteral nutrition after surgery.","authors":"Can Kong, Dingsheng Kong, Junjie Hu, Lianggong Liao, Zhiguo Xiong, Tao Fu","doi":"10.3389/fvets.2025.1626574","DOIUrl":"10.3389/fvets.2025.1626574","url":null,"abstract":"<p><strong>Background: </strong>This study aims to establish a mouse model with different nutritional support modalities [enteral nutrition (EN) and parenteral nutrition] after abdominal surgery, providing a stable and effective animal model for further study on the intestinal barrier damage caused by total parenteral nutrition.</p><p><strong>Methods: </strong>Twenty mice were randomly assigned to either an enteral nutrition (EN) group (<i>n</i> = 10) or a total parenteral nutrition (TPN) group (<i>n</i> = 10). After abdominal surgery via appendectomy, the two groups of mice received different modes of nutritional support (TPN or EN). A properly sized central venous catheter was placed in the right internal jugular or an enteral nutrition catheter was inserted into the duodenum. Parenteral or enteral nutrition was infused through these catheters. The survival rate, intestinal villus height, epithelial cell proliferation, changes in goblet cells and Paneth cells, as well as the expression levels of the tight junction (TJ) proteins ZO-1 and occludin, were observed.</p><p><strong>Results: </strong>No difference was found in survival rate (<i>P</i> < 0.01) between the two groups. However, significant differences were observed in the height of small intestinal villi, epithelial proliferation rate, number of goblet cells [Periodic Acid-Schiff (PAS+)], Paneth cell function (Lysozyme+), and expression of ZO-1 and occludin proteins. All of these markers were significantly decreased in the TPN group compared to the EN group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The mouse model is suitable and effective for investigating the pathogenesis of intestinal barrier dysfunction, as it provides different types of nutritional support after abdominal surgery.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1626574"},"PeriodicalIF":2.9,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the motivations, deterrents, and incentives for rural Albertan veterinary practice.","authors":"Hanna Mughal, Thomas A O'Neill, Lena Le Huray, Megan Bergman, John Remnant, Angelica M Galezowski, Kent G Hecker, Robert McCorkell","doi":"10.3389/fvets.2025.1633149","DOIUrl":"10.3389/fvets.2025.1633149","url":null,"abstract":"<p><strong>Introduction: </strong>The shortage of rural veterinarians is a growing concern globally. This shortage increases the risk of significant negative impacts on livestock management, agriculture, and public health in rural and remote communities. To provide concrete solutions to sustain our rural veterinarian workforce, we examine motivations, incentives, and deterrents to rural veterinary practice (RVP). We do this through a qualitative study in Alberta, Canada, which is a geographically unique and understudied context.</p><p><strong>Methods: </strong>We surveyed veterinary students and practicing veterinarians, obtaining 124 responses. Data were analyzed using thematic analysis.</p><p><strong>Results: </strong>Results revealed key motivating factors that influence attraction and retention included personal and family considerations that require living in rural contexts, the nature of strong relationships that develop in rural communities, experiencing a range in work factors that enhances professional development, feeling fulfilled by rural veterinary work, and exposure during veterinary school leading to a strong interest in rural settings. Deterrents included limited resources and supports in rural contexts, personal and family needs that require living in urban settings, and challenges inherent to rural communities and environmental characteristics. Finally, key incentives included better salary and benefits, financial incentives, tuition/debt forgiveness, enhanced mentorship, fewer on-call duties, and tailored incentives.</p><p><strong>Discussion: </strong>Strong alignment between student and practicing veterinarian motivations, deterrents, and incentives was observed, extending previous findings that only look at the perceptions of a single group. The results corroborated previous findings, while revealing that the same motivations and deterrents remained important for students and PVs in Alberta's geographically unique context. Finally, they provided key insights to inform policy, practice, and education developments to enhance attraction and retention rates of rural veterinarians, contributing to a path forward for addressing the rural shortage of veterinary services.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1633149"},"PeriodicalIF":2.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12488401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrotizing <i>E. coli</i> pneumonia with subsequent pneumothorax in a dog: a case report.","authors":"Victoria Vida Vazin, Sara Huebner, Teagan Deforge, Michael Wood, Athanasia Mitropoulou","doi":"10.3389/fvets.2025.1587810","DOIUrl":"10.3389/fvets.2025.1587810","url":null,"abstract":"<p><p>Necrotizing pneumonia is a poorly described and rarely reported phenomenon in veterinary medicine. The objective of this case report is to describe the successful management of a case of necrotizing pneumonia in a dog requiring medical and surgical management. This case describes a 9-year-old male neutered Siberian Husky mix that presented to an emergency center for a chronic cough not responsive to antibiotics including doxycycline and amoxicillin-clavulanate. Diagnostic imaging studies were consistent with severe multilobular pneumonia, pleural effusion and secondary pneumothorax. Aerobic culture of a bronchoalveolar lavage sample isolated <i>Escherichia coli</i> that was susceptible to enrofloxacin. A median sternotomy was performed when antibiotics alone were unable to fully clear the infection and the cranial segment of the left cranial lung lobe was removed. Histopathology of this lung lobe indicated subacute suppurative and fibrinohemorrhagic bronchopneumonia with parenchymal and pleural necrosis. The dog survived to discharge with resolution of pneumonia based on thoracic radiographs after 38 days. Necrotizing pneumonia can potentially be adequately treated with appropriate escalation of medical and surgical management.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"12 ","pages":"1587810"},"PeriodicalIF":2.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}