Frontiers in Veterinary Science最新文献

{"title":"Environmental surveillance: harnessing environmental sample data to protect animal health.","authors":"Bayyppa Gundallahalli Manjunatha Reddy, Uzma Jabeen, Hinal Kharva, Muthannan Andavar Ramakrishnan","doi":"10.3389/fvets.2026.1965480","DOIUrl":"https://doi.org/10.3389/fvets.2026.1965480","url":null,"abstract":"<p><p>Infectious diseases in domestic animals-including those with zoonotic potential-impose a substantial global burden on food security, livelihoods, and public health. Environmental surveillance (ES) offers a critical complement to conventional animal-level diagnostics by detecting pathogens or their genetic signatures directly in the matrices through which they persist and spread: water, soil, air, manure, fomites, and arthropod vectors. This review synthesizes evidence across three analytical dimensions-matrix suitability, detection method performance, and wastewater-based epidemiology (WBE)-for 15 viral, bacterial, and parasitological diseases of domestic animals. Key findings reveal that matrix choice profoundly governs detection sensitivity: surface water and wetland sediments support infectious avian influenza virus isolation; pooled environmental feces and slurry outperform individual animal sampling for <i>Mycobacterium avium subsp. paratuberculosis</i> (MAP); and electrostatic dust cloths enable simultaneous detection of peste-des-petits ruminants virus (PPRV) and capripoxviruses at livestock markets. Molecular methods, principally quantitative RT-PCR and droplet digital PCR, consistently outperform conventional culture in sensitivity and turnaround time, though viability-linked assays remain an important unresolved need. WBE is increasingly applied beyond human pathogens: piggery effluent surveillance for Japanese encephalitis virus and wastewater metagenomics for antimicrobial resistance exemplify its veterinary potential. Interpretive limitations persist, including matrix-driven inhibition, absence of harmonized protocols, and the challenge of equating nucleic-acid signals with infectious risk. Realizing the full promise of ES within a One Health framework requires standardized, field-validated sampling workflows, viability-linked molecular assays, and formal integration of environmental signals into routine veterinary surveillance and outbreak-response systems.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1965480"},"PeriodicalIF":3.1,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and surgical outcomes of full-thickness abdominal wall injuries complicated by evisceration and fistulation in dromedary camels (<i>Camelus dromedarius)</i>.","authors":"El-Sayed El-Shafaey, Mahmoud Najeb, Mohamed Abdo Rizk, Mahmoud G El Sebaei","doi":"10.3389/fvets.2026.1926549","DOIUrl":"https://doi.org/10.3389/fvets.2026.1926549","url":null,"abstract":"<p><strong>Background: </strong>Abdominal wall injuries in dromedary camels often result in life-threatening evisceration or persistent fistulation. While well documented in equines and bovines, standardized surgical management protocols and survival outcomes for camelids remain scarce in veterinary literature. This retrospective study evaluated the clinical patterns, visceral involvement, surgical treatments, and survival outcomes of full-thickness abdominal wall injuries complicated by evisceration or fistulation in dromedary camels.</p><p><strong>Methods: </strong>A retrospective study was conducted on 14 dromedary camels presenting with full-thickness abdominal wall trauma complicated by acute evisceration (<i>n</i> = 11) or chronic fistulation (<i>n</i> = 3) at a specialized camel hospital between September 2023 and December 2025. All animals underwent detailed clinical and ultrasonographic examinations. Surgical management was tailored according to lesion type, tissue viability, and the degree of contamination.</p><p><strong>Results: </strong>Females (85.7%) and the Wadeh breed (78.6%) were predominantly affected. Injury distribution was equally split between ventral/umbilical (50.0%) and ventrolateral (50.0%) zones, driven by external trauma (57.1%), hernia rupture (28.6%), or gastroschisis (14.3%). The intestines were the most frequently involved viscera (50.0%), and gross environmental contamination was present in 78.6% of cases. One camel (7.1%) died during initial stabilization. Following surgery of acute evisceration cohort, (63.6%) (7/11) survived and were successfully discharged from the hospital. Conversely, 27.3% (3/11) of the camels developed rapid hemodynamic collapse and hyperacute systemic sepsis within 24-48 h post-injury, which resulted in death. Postoperative recovery and successful hospital discharge of chronic fistulation were achieved in 66.7% (2/3) of the cases. One camel (33.3%, 1/3) developed uncontrollable severe sepsis secondary to chronic focal necrosis on postoperative day 4 and died.</p><p><strong>Conclusion: </strong>Accurate rapid diagnosis and prompt surgical interventions of full-thickness abdominal wall injuries complicated by evisceration and fistulation can yield a favorable prognosis in dromedary camels. Lesion type, tissue viability, and injury duration are the key factors influencing management choices and overall prognosis for camelid full-thickness abdominal wall injuries.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1926549"},"PeriodicalIF":3.1,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Vibrio alginolyticus</i>: an emerging marine pathogen at the intersection of aquaculture, public health, and antimicrobial resistance.","authors":"Songlin Wei, Jingmin Lin, Ruichao Xue, Wei Xu","doi":"10.3389/fvets.2026.1965608","DOIUrl":"https://doi.org/10.3389/fvets.2026.1965608","url":null,"abstract":"<p><p><i>Vibrio alginolyticus</i> is a halophilic, Gram-negative marine bacterium that has emerged as a significant opportunistic pathogen affecting both marine animals and humans. As one of the most abundant vibrios in coastal and estuarine environments worldwide, <i>V. alginolyticus</i> causes substantial economic losses in aquaculture through vibriosis in fish, shrimp, and shellfish, while also being responsible for wound infections, otitis externa, and occasionally gastroenteritis in humans following seawater exposure or seafood consumption. The pathogenesis of <i>V. alginolyticus</i> is multifactorial, involving an arsenal of virulence determinants including secretion systems (type III, type VI, and type II), haemolysins, adhesins, biofilm formation, quorum sensing-regulated factors, and the recently recognized contributions of non-coding RNAs and outer membrane vesicles. Recent genomic analyses have revealed considerable genetic diversity among isolates and identified a ubiquitous presence of β-lactam resistance genes, raising concerns about natural resistance and the potential for horizontal gene transfer. The interplay between rising seawater temperatures, intensive aquaculture practices, and increasing antimicrobial resistance has positioned <i>V. alginolyticus</i> as an emerging pathogen of growing concern. This Review synthesizes current knowledge on the epidemiology, genomics, virulence mechanisms, host interactions, and control strategies of <i>V. alginolyticus</i>, with an emphasis on the molecular determinants of pathogenesis, including the regulatory networks governing adhesion, biofilm formation, and metabolic adaptation, and the challenges posed by antimicrobial resistance. We also discuss promising alternative control approaches, including phage therapy, vaccination, and probiotic strategies, and identify key knowledge gaps that warrant future investigation.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1965608"},"PeriodicalIF":3.1,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing gastroenteritis in puppies: veterinary practices in Trinidad and Tobago and Barbados.","authors":"Natasha Mootoo, Anya Doorpat, Fariah Karim, Karishma Maharajh, Oluwatomi Oredein, Kegan Romelle Jones","doi":"10.3389/fvets.2026.1813429","DOIUrl":"https://doi.org/10.3389/fvets.2026.1813429","url":null,"abstract":"<p><p>This research explored the approaches of veterinarians to diagnosis and treatment of gastroenteritis in puppies up to 1 year of age in Trinidad and Tobago and Barbados. The study assessed clinical decision-making, therapeutic interventions, and utilisation of evidence-based practices. Data were gathered from veterinarians through online surveys and semi-structured interviews. The study revealed a significant association between the diagnosis of parvovirus and hospitalisation (<i>p</i> < 0.001), as well as between the diagnosis of parvovirus and intravenous (IV) fluid administration (<i>p</i> = 0.002). All veterinarians used a multi-drug regimen in treatment. Similarities in treatment protocols among veterinarians with different years of activity were observed, with the most used therapeutic agents being lactated ringer's solution (fluid therapy), metronidazole (antibiotic), vitamins (nutraceutical), metoclopramide (antiemetic), and Fortiflora® (probiotic). Based on the data collected, symptomatic treatment modalities consistent with current international literature are widely utilized by the veterinarians in Barbados. However, due to a low response rate, the same cannot be concluded for Trinidad and Tobago.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1813429"},"PeriodicalIF":3.1,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bovine blood products modulate the effect of ophthalmic antibiotics against common bacterial pathogens in dogs with infectious keratitis.","authors":"Helen O Kim, Melissa A Kubai, Levi Brock, Chloe C Stinman, Janelle Gapp, Danyang Zhang, Rachel A Allbaugh","doi":"10.3389/fvets.2026.1880844","DOIUrl":"https://doi.org/10.3389/fvets.2026.1880844","url":null,"abstract":"<p><p>Bacterial keratitis is a common condition that can result in serious complications including vision impairment and loss of the eye if not treated aggressively. Topical blood products are often utilized concurrently with topical antibiotics for their known anti-collagenolytic properties. These blood products contain albumin that could affect the antibiotic efficacy due to drug-protein binding. In this study, serum and plasma were harvested from 10 healthy bovines, utilizing fresh and frozen (1 month at -20 °C) aliquots for the experiment. Albumin and alpha-2 macroglobulin levels were quantified using species-specific ELISA kits. 30 bacterial isolates (10 <i>Staphylococcus pseudintermedius</i>, 10 <i>Streptococcus canis</i>, 10 <i>Pseudomonas aeruginosa</i>), isolated from canine patients with infectious keratitis were tested with blank plates as well as commercial susceptibility plates (Sensititre™ JOEYE2) to assess the minimal inhibitory concentration (MIC) of 17 different antibiotics in the absence (control) or presence of serum or plasma (fresh or frozen) from bovines (4 test groups). Mean bovine albumin levels ranged from 1.98 to 2.00 mg/ml. The median bovine alpha-2 macroglobulin levels were similar between frozen serum (4,403 ng/ml [range 3,542-5,499 ng/ml]) and frozen plasma (4,959 ng/ml [range 3,305-5,447 ng/ml]). No bacteriological susceptibility differences were noted between fresh and frozen samples for either serum or plasma. Bovine serum/plasma had direct antimicrobial effects in selected bacterial isolates (up to 49% with frozen plasma for <i>Staphylococcus pseudintermedius</i>). When compared with control, bovine serum/plasma increased MICs (1.33-4-fold) or decreased MICs (0.5-0.75 fold) depending on the specific antibiotic and bacterial isolate. In practice, clinicians should consider using bovine serum/plasma over other species' blood products (equine or canine) given direct antimicrobial effects, good anti-collagenolytic potential, and lesser impact on antimicrobial susceptibility to topical antibiotics. Serum and plasma can alter antibiotic efficacy (antibiotic-protein binding from high levels of albumin); therefore, serum/plasma should be applied last and spaced ≥15 min after topical antibiotics.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1880844"},"PeriodicalIF":3.1,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hematologic follow-up of metamizole-associated Heinz body anemia in dogs.","authors":"Cathrina Richter, Vera Geisen, Jelena Palić, René Dörfelt","doi":"10.3389/fvets.2026.1913770","DOIUrl":"https://doi.org/10.3389/fvets.2026.1913770","url":null,"abstract":"<p><strong>Introduction: </strong>Heinz body (HB) anemia is uncommon in dogs. Metamizole is described as a potential trigger in isolated cases.</p><p><strong>Aim of the study: </strong>The present study describes the course of metamizole-associated HB anemia in dogs with the development of hematocrit, HBs, and eccentrocytes. In addition, the correlation between HBs, eccentrocytes, hematocrit, and reticulocytes is investigated.</p><p><strong>Materials and methods: </strong>In this prospective observational study, 25 dogs with metamizole-associated HB anemia were included. Hematologic examinations and blood smear evaluations for quantification of HBs and eccentrocytes (stained with brilliant cresyl blue and modified Wright's stain) were performed on day 0 and at the control intervals 1-3, 4-6, 7-13, and 14-20 days after discontinuation of metamizole and initiation of antioxidant treatment. Known alternative causes of oxidative erythrocyte damage were excluded. Data were analyzed using Kruskal-Wallis test, Friedman test, and Spearman correlation.</p><p><strong>Results: </strong>HB anemia was detected a median of 10 days after initiation of metamizole (median cumulative dose 720 mg/kg). On day 0, HB percentage did not correlate with metamizole dose or hematocrit. The eccentrocyte count did not correlate with metamizole dose, hematocrit, or reticulocyte count. However, a moderate to strong correlation was identified between HB percentage and reticulocyte count (<i>r</i> = 0.630). Median HBs and eccentrocytes decreased from 26.5% and 2.6% on day 0 to 1.3% and 0% on days 14-20, while median hematocrit increased from 24 to 33%. Four dogs received blood transfusions. All patients had at least one concurrent disease. Twenty-one dogs survived and four dogs were euthanized or died.</p><p><strong>Conclusion: </strong>In dogs with concurrent disease, metamizole administration may be associated with clinically relevant erythrocyte oxidative damage. Discontinuation of metamizole and initiation of antioxidant therapy were followed by a decrease in HBs and recovery of hematocrit. The use of metamizole in multimorbid dogs should be carefully considered and accompanied by regular hematology controls.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1913770"},"PeriodicalIF":3.1,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bleomycin-based electrochemotherapy for recurrent oral CD8-positive epitheliotropic T-cell lymphoma in a dog with durable local control and necrotic regional lymph node changes: a case report.","authors":"Makoto Akiyoshi, Masaharu Hisasue","doi":"10.3389/fvets.2026.1942467","DOIUrl":"https://doi.org/10.3389/fvets.2026.1942467","url":null,"abstract":"<p><strong>Background: </strong>Oral epitheliotropic T-cell lymphoma (ETCL) is an uncommon form of canine cutaneous lymphoma involving the oral mucosa and mucocutaneous junctions. Information regarding optimal treatment strategies and prognosis is limited. Electrochemotherapy (ECT) has demonstrated efficacy against various cutaneous and subcutaneous tumors in dogs and cats; however, reports describing its use for canine oral ETCL are scarce.</p><p><strong>Case description: </strong>A 13-year-old male Beagle presented with multiple nodular lesions involving the right maxillary gingiva, buccal mucosa, and mandibular gingiva. Histopathology and immunohistochemistry confirmed CD8-positive epitheliotropic T-cell lymphoma, with more than 90% of neoplastic cells expressing CD3 and CD8. Initial treatment with oclacitinib resulted in a reduction in the size and number of the oral lesions; however, disease progression was observed after 149 days. Bleomycin-based electrochemotherapy (BLM-ECT) was subsequently performed using intravenous bleomycin (20 mg/m²) followed by electric pulse delivery with a four-needle electrode (1,000 V/cm, eight pulses). Two BLM-ECT sessions were administered on days 205 and 238, resulting in marked reduction in the size and number of the oral lesions and prolonged local disease control. On day 354, enlargement of the left mandibular lymph node was observed. Histopathological examination revealed extensive necrosis that precluded definitive determination of lymphoma involvement. Although residual CD3-positive lymphocytes were identified, neither flow cytometry nor polymerase chain reaction for antigen receptor rearrangement (PARR) confirmed a neoplastic lymphoid population. A third BLM-ECT session was performed on day 555 for recurrent erythematous lesions of the median upper and lower lip mucosa, in which T-cell lymphoma was histologically confirmed. At the latest evaluation on day 608, no grossly visible oral lesions were detected, and there was no clinical evidence of systemic dissemination. The dog remained clinically well.</p><p><strong>Conclusion: </strong>BLM-ECT provided prolonged local disease control in a dog with recurrent multifocal oral CD8-positive ETCL that had progressed despite oclacitinib treatment. Unusual necrotic changes also developed in regional lymph nodes. The etiology of these changes remained undetermined, and a causal relationship with ECT could not be established. Investigation of pathological and immunological changes following ECT is warranted. BLM-ECT may represent a feasible and repeatable local treatment option for selected dogs with oral ETCL.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1942467"},"PeriodicalIF":3.1,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Statistical shape modeling of the geometric morphology of the canine femur, tibia, and patella.","authors":"Jeremy Huart, Antonio Pozzi, Jason Bleedorn, Tung-Wu Lu, Sebastian Knell, Brian Park","doi":"10.3389/fvets.2026.2000605","DOIUrl":"https://doi.org/10.3389/fvets.2026.2000605","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fvets.2024.1366827.].</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"2000605"},"PeriodicalIF":3.1,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of quercetin supplementation on the quality and metabolomic characteristics of sex-sorted frozen semen from Australian Wagyu bulls.","authors":"Chao Yuan, Yuefu Yin, Xin Wang, Bo Yu, Junda Wu, Yuanfeng Zhao, Jing Liu, Kaikai Zhang, Wenzhang Zhou, Yongcai Zhu, Longxin Xu","doi":"10.3389/fvets.2026.1951637","DOIUrl":"https://doi.org/10.3389/fvets.2026.1951637","url":null,"abstract":"<p><p>This study aimed to evaluate the effects of different concentrations of quercetin on the post-thaw sperm quality of sex-sorted frozen semen from Australian Wagyu bulls and to investigate the underlying metabolic regulatory mechanisms using untargeted metabolomics. Sex-sorted frozen semen from Australian Wagyu bulls was treated with 0, 10, 50, 100, 150, and 200 μM quercetin. Sperm motility parameters, plasma membrane integrity, acrosome integrity, mitochondrial membrane potential, DNA integrity, reactive oxygen species (ROS) levels, and antioxidant-related indices were assessed. Metabolomic profiling was further performed to compare the 50 μM quercetin-treated group with the control group. The results showed that the 50 μM quercetin group exhibited better sperm viability, motility, straight-line velocity (VSL), curvilinear velocity (VCL), and average path velocity (VAP), together with reduced ROS levels and increased activities of antioxidant enzymes, including SOD, CAT, and GSH-Px. High concentrations of quercetin (≥150 μM) adversely affected sperm motility and several functional parameters. Metabolomic analysis revealed clear metabolic differences between the 50 μM quercetin-treated group and the control group, with 131 upregulated and 395 downregulated differential metabolites identified. KEGG enrichment analysis indicated that these differential metabolites were mainly involved in lipid-related pathways, including glycerophospholipid metabolism and arachidonic acid metabolism. These results suggest that an appropriate concentration of quercetin may improve the post-thaw quality of sex-sorted frozen semen from Australian Wagyu bulls by alleviating oxidative stress and regulating lipid metabolism. This study provides experimental evidence and metabolomic insights for optimizing cryoprotectant formulations for bovine sex-sorted frozen semen.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1951637"},"PeriodicalIF":3.1,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term CT and US imaging of canine prostatic carcinoma after prostatic artery embolization: a 900-day follow-up case report.","authors":"Saneyuki Isshiki, Sachiyo Tsuji-Kawahara, Mayu Ogata, Shinya Hisamoto, Moe Hashimoto, Tetsuya Hasegawa, Ikuo Tsunoda","doi":"10.3389/fvets.2026.1947473","DOIUrl":"https://doi.org/10.3389/fvets.2026.1947473","url":null,"abstract":"<p><p>Canine prostatic carcinoma is a highly aggressive malignancy with a poor prognosis and limited long-term treatment options. Prostatic artery embolization (PAE) has emerged as a minimally invasive alternative, but long-term intraprostatic imaging changes after PAE in dogs remain poorly documented. We performed PAE on a 13-year-old neutered male Chihuahua with prostatic carcinoma. Designating PAE as Day 0, we monitored the prostate, bladder, and lungs with computed tomography (CT), ultrasonography (US), and thoracic radiography for approximately 900 days. Clinical signs remained well controlled; the dog survived until Day 918. CT showed intraprostatic hypoattenuating lesions (Day 33) that enlarged with gas accumulation (Day 173); US showed hypoechoic lesions (Day 271) that became scattered hyperechoic foci (Day 678). Following PAE, the prostatic parenchymal volume decreased by approximately 33% and remained stable until Day 481. No serious PAE-related complications were observed. These findings suggest that PAE induced sustained ischemic, cavitary, and chronic remodeling changes within the prostate, which may have contributed to the prolonged local disease control observed in this dog. To our knowledge, this represents the longest time-course imaging reported after PAE in a dog with prostatic carcinoma and illustrates the potential of PAE as a feasible, minimally invasive treatment option in general veterinary practice.</p>","PeriodicalId":12772,"journal":{"name":"Frontiers in Veterinary Science","volume":"13 ","pages":"1947473"},"PeriodicalIF":3.1,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}