Frontiers in Pediatrics最新文献

{"title":"Breathe easy, baby, breathe. Lung ultrasound in neonatal critical care.","authors":"Mateusz Jagła, Andrzej Grudzień, Tomasz Tomasik, Michał Wroński, Przemko Kwinta","doi":"10.3389/fped.2025.1631563","DOIUrl":"10.3389/fped.2025.1631563","url":null,"abstract":"<p><p>Lung ultrasound (LUS) has emerged as an essential tool in neonatology over the past two decades, offering unique advantages for this patient population. The small size, high water content, and delayed rib calcification of neonates make them particularly suited for ultrasonographic imaging. By replacing traditional chest radiographs, it significantly reduces exposure to ionizing radiation. Furthermore, it is widely accessible, easy to use, and provides repeatable, real-time imaging without requiring patient transport. These features make it invaluable in managing acute respiratory conditions, where timely intervention is critical. This review emphasizes the role of LUS in neonates with acute respiratory distress as a fundamental component of the point-of-care ultrasound (PoCUS) protocol. The technique is crucial for conditions such as respiratory distress syndrome (RDS), supporting decisions on surfactant therapy. It also aids in diagnosing and managing air-leak syndromes like pneumothorax (PTX) and detecting congenital respiratory malformations. Additionally, LUS ensures safer transport of critically ill neonates and optimizes mechanical ventilation. By delivering accurate, real-time imaging, LUS has become an essential diagnostic tool in infant care. Its integration into clinical practice enhances the management of life-threatening conditions, making it an essential skill for clinicians in neonatal intensive care units (NICU) and during neonatal transport.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1631563"},"PeriodicalIF":2.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12500432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic ultrasound safety and efficacy in pediatric pancreatobiliary and gastrointestinal disorders: single-center retrospective trial.","authors":"Jiayu Zhang, Zhaohui Deng","doi":"10.3389/fped.2025.1684339","DOIUrl":"10.3389/fped.2025.1684339","url":null,"abstract":"<p><strong>Background: </strong>While endoscopic ultrasound (EUS) is well established as a standard diagnostic and therapeutic tool in adults, its use in children remains limited. This study assessed the indications, safety, and clinical impact of diagnostic and therapeutic EUS in children with pancreatobiliary and gastrointestinal disorders.</p><p><strong>Methods: </strong>We retrospectively analyzed pediatric patients with pancreatobiliary and gastrointestinal disorders who underwent EUS at our institution between January 2022 and June 2025.</p><p><strong>Results: </strong>Fifty-three EUS procedures were conducted in children with a median age of 9.6 ± 3.0 years. Indications for EUS included acute recurrent pancreatitis (<i>n</i> = 15), suspected chronic pancreatitis (<i>n</i> = 12), suspected choledocholithiasis (<i>n</i> = 7), obstructive jaundice (<i>n</i> = 5), pancreatic mass (<i>n</i> = 1), gastric mucosal lesions (<i>n</i> = 6), suspected esophageal lymphoma recurrence (<i>n</i> = 1), suspected autoimmune hepatitis (<i>n</i> = 1) and pancreatic pseudocyst (PPC, <i>n</i> = 5). ERCP was performed during the same anesthesia for all children requiring it post-EUS. Five patients underwent cystogastrostomy for symptomatic PPC with 100% technical and clinical success. The efficacy of EUS in guiding definitive therapeutic decisions and invasive interventions was 100%. Notably, no major complications occurred.</p><p><strong>Conclusion: </strong>EUS is safe and effective diagnostic and therapeutic modality in pediatric patients with pancreatobiliary and gastrointestinal disorders.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1684339"},"PeriodicalIF":2.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12500564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145250576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between objectively and subjectively measured sleep outcomes among elementary school children in Rhode Island.","authors":"Aliana Rodriguez Acevedo, Diane Story, Lovisa Werner, David H Barker, John E McGeary, Shira I Dunsiger, Diana S Grigsby-Toussaint","doi":"10.3389/fped.2025.1622943","DOIUrl":"10.3389/fped.2025.1622943","url":null,"abstract":"<p><strong>Objective: </strong>Although sleep is essential for healthy child development, parents generally misconstrue definitions of sleep duration and sleep quality. This study examines differences between objective and parent-reported measures of sleep in children, with a particular focus on Latino and non-Latino groups. We hypothesized that significant discrepancies exist between objective and subjective sleep measures and differences in sleep outcomes between Latino and non-Latino subgroups.</p><p><strong>Methods: </strong>Children in grades one, two, and three in Rhode Island (<i>n</i> = 102; age range 6-10 years; 57.8% female) wore an accelerometer for seven days to objectively measure time in bed, sleep duration, wake after sleep onset, and sleep latency. Parents also reported perceived sleep outcomes, and whether they believed their child generally \"sleeps the right amount\". Emphasis was placed on the Latino population.</p><p><strong>Results: </strong>Based on parent-reported sleep measures, 83.3% of children met sleep guidelines (defined as 9-12 h per night), compared to 14.7% based on accelerometry (<i>ρ</i> = -0.036, <i>p</i> = 0.711). Average sleep duration significantly differed between parent reports (9.58 h, SD = 1.42) and actigraphy (8.32 h, SD = 0.70; <i>ρ</i> = 0.405, <i>p</i> < 0.001). There were no discrepancies between objective and subjective reported sleep latency and WASO, although paired tests indicated significant within-person differences in WASO (<i>p</i> < .001). Finally, there were significant discrepancies in sleep duration between Latinos and non-Latinos, with Latino caregivers reporting significantly shorter sleep and their children experiencing shorter sleep duration as measured via actigraphy, and being less likely to meet sleep guidelines.</p><p><strong>Conclusion: </strong>These findings suggest that there is a discrepancy between perceived and objectively measured sleep. It also suggests discrepancies in sleep duration between Latino and non-Latino children, and differences in parental knowledge of sleep behaviors between Latinos and non-Latinos.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1622943"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for mortality and development of a predictive model in pediatric sepsis.","authors":"Caizhen Wang, Lijie Feng, Xiaohui Yang, Pan Wang, Yuan Chen","doi":"10.3389/fped.2025.1661086","DOIUrl":"10.3389/fped.2025.1661086","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical characteristics and risk factors associated with mortality in pediatric sepsis patients, and to establish a predictive model for early identification of high-risk children.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted including 143 pediatric sepsis cases admitted to the Pediatric Intensive Care Unit of the Second Hospital of Hebei Medical University from January 2020 to December 2024. Clinical data, laboratory indicators, and treatment history were collected. Univariate and multivariate logistic regression analyses were performed to identify risk factors for mortality. A nomogram model was constructed based on significant predictors, and its predictive performance was evaluated by receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>Among the 143 cases, 121 survived and 22 died. Significant differences were observed between the survival and death groups in lymphocyte count, platelet count, albumin, D-dimer, liver function tests (ALT, TBIL), CALLY index, and pre-admission glucocorticoid use (<i>P</i> < 0.05). Multivariate analysis identified platelet count (OR = 0.992, 95% CI: 0.987-0.997), D-dimer (OR = 7.571, 95% CI: 2.642-21.698), and CALLY index (OR = 0.532, 95% CI: 0.323-0.877) as independent risk factors for mortality. The nomogram model incorporating these factors showed good predictive accuracy with an area under the ROC curve of 0.859 (95% CI = 0.742-0.953).</p><p><strong>Conclusion: </strong>Platelet count, D-dimer level, and CALLY index are valuable indicators for assessing prognosis in pediatric sepsis and can aid in early risk stratification. The established nomogram provides a useful tool for clinical decision-making to improve outcomes in high-risk pediatric sepsis patients. Further multicenter prospective studies are warranted to validate and refine these findings.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1661086"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Clinical case analysis of gaucher disease management in a resource-limited setting: a single center experience from Kashigar, Xinjiang Uygur Autonomous Region, the Western China.","authors":"Gulinuer Maimaititusvn, Maierhaba Kulaixi, Abudouwaili Atawula, Fang Liu","doi":"10.3389/fped.2025.1530177","DOIUrl":"10.3389/fped.2025.1530177","url":null,"abstract":"<p><strong>Objective: </strong>This report presents the inaugural case of Gaucher disease identified in Kashgar Prefecture, Xinjiang, the westernmost region of China. It emphasizes an analysis of the clinical characteristics, diagnostic challenges, and treatment strategies within the unique geographical, cultural, and ethnic contexts. The study aims to investigate potential associations between environmental factors, genetic backgrounds, and lifestyle in Kashgar Prefecture, as they relate to the diagnosis, treatment, and prognosis of Gaucher disease, with the goal of optimizing diagnostic and therapeutic approaches in similar regions.</p><p><strong>Methods: </strong>We performed a retrospective analysis of the patient's clinical data, employing advanced diagnostic methods in conjunction with multidisciplinary collaboration. The data encompassed clinical symptoms, laboratory tests, imaging examinations, genetic testing, diagnostic procedures, and individualized treatment plans.</p><p><strong>Results: </strong>A 12-year-old female patient from Kashgar, Xinjiang, China, presented with chronic anemia, hepatosplenomegaly, thrombocytopenia, recurrentepistaxis, and osseous pain. She was diagnosed with Gaucher disease type I through genetic testing and enzymatic examination. This case represents the first reported instance of this condition in the Xinjiang region. Notably, it exhibited unique clinical features, including the age of onset, severity of symptoms, and potential regional complications. Treatment with high-dose ambroxol and imiglucerase significantly alleviated the patient's symptoms, and continuous follow-up was conducted to assess long-term efficacy.</p><p><strong>Conclusion: </strong>This report underscores the critical importance of early diagnosis and timely intervention in the management of Gaucher disease, particularly in regions with limited medical resources such as Kashgar. The successful diagnosis and treatment of this case have facilitated communication and cooperation between primary healthcare units and external medical institutions. This has further driven interactions in various aspects such as academic exchanges, teleconsultations, and medical assistance. In turn, this has provided a solid foundation for safeguarding patients' rights and improving medical services.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1530177"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neonatal anemia due to spontaneous fetomaternal hemorrhage in a term neonate: a case report of an incidental finding and brief review.","authors":"Xinxin Hao, Yuyu Zhang, Chang Gao, Qiushi Wang","doi":"10.3389/fped.2025.1625557","DOIUrl":"10.3389/fped.2025.1625557","url":null,"abstract":"<p><p>Fetomaternal hemorrhage (FMH) is a rare perinatal condition characterized by the transplacental transfer of fetal erythrocytes into the maternal circulation. It poses significant risks, including fetal anemia, hydrops fetalis, and maternal alloimmunization, and often remains underdiagnosed due to non-specific clinical presentations and limited diagnostic accessibility. We present a case of a term neonate delivered via cesarean section at 38 weeks' gestation who exhibited severe anemia and hyperbilirubinemia. Blood group analysis revealed maternal-neonatal Rh incompatibility, while flow cytometry quantified 2.0% fetal erythrocytes in maternal blood. This case underscores the diagnostic value of integrating blood group serology and flow cytometry in FMH confirmation, particularly when standard tests yield equivocal results. A multidisciplinary evaluation of the fetus is the key to early diagnosis and intervention to improve the clinical outcome of perinatal infants.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1625557"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Multidisciplinary approaches in pediatric gastrointestinal and liver diseases.","authors":"Maria Oana Săsăran, Ancuța Lupu, Vasile Valeriu Lupu","doi":"10.3389/fped.2025.1678818","DOIUrl":"https://doi.org/10.3389/fped.2025.1678818","url":null,"abstract":"","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1678818"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and duration of clinical symptoms of pediatric long COVID: findings from a one-year prospective study.","authors":"Vita Perestiuk, Tetyana Kosovska, Liubov Volianska, Oksana Boyarchuk","doi":"10.3389/fped.2025.1645228","DOIUrl":"10.3389/fped.2025.1645228","url":null,"abstract":"<p><strong>Background: </strong>Long COVID in children remains a poorly understood condition with wide variability in clinical presentation, duration, and risk factors. <b>The aim of this study</b> was to assess the prevalence, spectrum, and duration of long COVID symptoms in pediatric patients following acute SARS-CoV-2 infection using a standardized follow-up tool.</p><p><strong>Methods: </strong>We conducted a prospective cohort study involving 127 unvaccinated children aged 1 month to 18 years with long COVID according to the WHO definition and confirmed SARS-CoV-2 infection. Participants were followed up at 1-3, 3-6, 6-9, and 9-12 months post-infection using an adapted ISARIC Global Pediatric COVID-19 Follow-Up Questionnaire.</p><p><strong>Results: </strong>Persistent symptoms of long COVID were reported in 85.8% of patients at 3 months, decreasing to 56.1% at 9 months and 32.5% at 12 months. The most common long-term symptoms included fatigue (52.0%), reduced physical activity (44.1%), and headache (35.3%). Multivariable logistic regression showed that older age was significantly associated with a higher risk of decreased physical activity (OR = 1.51, <i>p</i> = 0.038), lack of energy (OR = 2.00, <i>p</i> = 0.003), neurological symptoms (OR = 1.86, <i>p</i> = 0.007), headache (OR = 4.51, <i>p</i> = 0.000), memory impairment (OR = 5.12, <i>p</i> = 0.000), difficulty communicating (OR = 4.28, <i>p</i> = 0.000), difficulty concentrating (OR = 2.74, <i>p</i> = 0.001), cardiological symptoms (OR = 2.34, <i>p</i> = 0.022), sensory symptoms (OR = 2.66, <i>p</i> = 0.011), and dizziness (OR = 10.02, <i>p</i> = 0.034). Younger age was associated with insomnia (OR = 0.49, <i>p</i> = 0.018). Female sex was significantly associated with a greater likelihood of lack of energy (OR = 2.55, <i>p</i> = 0.048). Hospitalization status was only significantly associated with muscle pain, with outpatients more frequently affected (OR = 0.28, <i>p</i> = 0.029).Overall, 32.5% of all participants continued to experience symptoms of long COVID more than one year acute infection, with fatigue persisting in 19.8%, reduced physical activity in 13.9%, headache in 12.3%.</p><p><strong>Conclusions: </strong>Long COVID affects children across all age groups and may persist beyond one year in a significant subset. These findings highlight age- and sex-specific symptom profiles and underscore the need for structured pediatric follow-up.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1645228"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of preterm neonatal mortality in the neonatal intensive care unit at a tertiary medical institution in Ethiopia.","authors":"Tihun Feleke, Gudeta Kaweti","doi":"10.3389/fped.2025.1414127","DOIUrl":"10.3389/fped.2025.1414127","url":null,"abstract":"<p><strong>Background: </strong>Premature death is a serious health concern in developing countries, including Ethiopia.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted in Hawassa University Comprehensive Specialized Hospital from 9 May 2019 to 22 April 2021. A total of 723 preterm neonates were enrolled in this study. The Kaplan-Meier survival curve was used to calculate the survival rate. The Cox proportional hazard ratio was used to evaluate the relationship between the dependent and independent variables. A 95% confidence level was used to check for significance.</p><p><strong>Results: </strong>Preterm neonatal mortality accounted for 33.3% of neonatal admissions. Early neonatal sepsis [adjusted hazard ratio (AHR) = 1.34; 95% CI: 1.003, 1.79], a 5-min Apgar score of less than 7 (AHR = 1.73; 95% CI: 1.17, 2.55), perinatal asphyxia (AHR = 2.25; 95% CI: 1.67, 3.02), and recent multiple pregnancies (AHR = 1.66; 95% CI: 1.22, 2.26) were predictors of preterm neonatal mortality.</p><p><strong>Conclusion: </strong>Early breastfeeding, prevention and early treatment of perinatal hypoxia and neonatal infections, identification, and monitoring of multiple pregnancies could help to reduce preterm neonatal mortality.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1414127"},"PeriodicalIF":2.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the current transition readiness of adolescent patients with kidney disease and the factors influencing it.","authors":"Shuo Bai, Maomao Lv, Jinteng Liu, Wenjun Liu, Lili Jia","doi":"10.3389/fped.2025.1613963","DOIUrl":"10.3389/fped.2025.1613963","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the transition readiness of adolescent patients with kidney disease to understand their readiness status and ability to transition to adult healthcare and study the influencing factors, to provide a theoretical basis for improving the transition readiness of adolescent patients with kidney disease and developing intervention strategies.</p><p><strong>Methods: </strong>The study sample was obtained from the follow-up data of the pediatric department at the General Hospital of the Eastern Theater of Operations from December 2024 to January 2025, and patients aged 13-18 years with renal disease were selected as the study subjects. The scores of the Chinese version of the Self-Management and Transitional Readiness Questionnaire were used to determine the readiness status of the study subjects, and binary logistic regression was used to analyze the influencing factors.</p><p><strong>Results: </strong>A total of 242 questionnaires were distributed, and 12 invalid questionnaires were excluded, resulting in the inclusion of 230 samples for the analysis. Transitional readiness was at a low level in 123 cases (53.48%) and at a medium-high level in 107 cases (46.52%). The results of the binary logistic regression showed that the number of hospitalizations, treatment modalities, place of residence, caregiver's literacy, monthly income, and healthcare payment method were influencing factors for transition readiness in adolescent patients with kidney disease (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The readiness of adolescent patients with kidney disease during their transition to adulthood is not ideal and is affected by a combination of factors related to themselves, their families, and their socioeconomic status. The relevant medical personnel should implement a multidimensional approach and carry out targeted interventions to improve these patients' readiness for the transition.</p>","PeriodicalId":12637,"journal":{"name":"Frontiers in Pediatrics","volume":"13 ","pages":"1613963"},"PeriodicalIF":2.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}