Functional Foods in Health and Disease最新文献

{"title":"Juice yield and pectin indicators in apple and carrot pomace","authors":"Arkan Al-Yasari, Nadezhda Barakova, Reem Alkhateeb, Filipp Hovhannisyan, Angelina Baskovtcev, Elena Kiprushkina","doi":"10.31989/ffhd.v13i11.1186","DOIUrl":"https://doi.org/10.31989/ffhd.v13i11.1186","url":null,"abstract":"Background: Pectin exhibits different properties based on its degree of esterification, forming gels and serving as a structure-forming agent in food products, or forming complexes with heavy metal ions, finding applications in the development of therapeutic products for the elimination of heavy metal ions from the human body. Context and purpose of this study: The purpose of this study is to investigate the influence of enzymatic treatment on the yield and quality of apple and carrot juices, as well as the quality parameters of pectin in pomace. Our objectives were to select an enzymatic preparation for processing apple and carrot pomace and to study changes in the properties of pectins present in the pomace depending on the dosage of the enzyme preparation.Results: The results of our experiments revealed that for apple pomace processing, it is more beneficial to use the enzyme preparation Vegazym M with a dosage of 0.09% of the pomace mass, while for carrot pomace processing, the enzyme preparation Fructozym MA with a dosage of 0.07% of the pomace mass proved to be the most suitable. These enzyme preparations in the specified amounts ensure maximum juice yield. It has been established that changing the dose of enzymes changes the complexing properties of pectin, which allows its use in food products with therapeutic and prophylactic properties.Conclusions: The enzyme preparations allow for specific modifications, such as pectin modification in this case, enabling the versatile use of pectin as either a structure-forming agent or for the development of therapeutic and preventive food products.Keywords:Apple and carrot juices, enzyme preparations, apple and carrot pomace, pectin, soluble and insoluble pectin, degree of esterification and pectin complexation, functional products.","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"33 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135876282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The phytochemical study of Eleutherococcus senticosus (Rupr. & Maxim) leaves in hydroponics and soil culture","authors":"Anush Vardanyan, Laura Ghalachyan, Anna Tadevosyan, Varduhi Baghdasaryan, Anjelika Stepanyan, Mahsa Daryadar","doi":"10.31989/ffhd.v13i11.1183","DOIUrl":"https://doi.org/10.31989/ffhd.v13i11.1183","url":null,"abstract":"Background: In the medical fieldEleutherococcus senticosus (Rupr. & Maxim) (E. senticosus) or Siberian ginseng is known as a natural adaptogen and immunomodulator. All parts of E. senticosus: roots, stems, leaves, and berries, have medicinal properties. In medicine, E. senticosus is used to treat depression, Alzheimer's and Parkinson’s diseases, cardiovascular diseases, cerebral ischemia, and diabetes. The adaptogenic properties of the plant are related to its rich composition of biologically active compounds (phenylpropanoids, eleuterosides, flavonoids, phenolic acids, anthocyanins, vitamins, etc.). E. senticosus activates the body’s protection mechanisms, directly affecting tissue metabolism. It increases mental and physical performance, immunity, and protects from stress, making its use important in sports medicine and the military. The use of E. senticosus in food and dietary supplements has become popular in recent years, whereas some studies suggest that its potential benefits are the reduction of stress and enhancement of immune system function. Objective: To study the content of the main biologically active compounds of medicinal raw material (leaves) of E. senticosus, cultivated in outdoor hydroponics and soil conditions during different stages of growth and development. Methods: The spectrophotometric method was used to determine the content of total phenols, flavonoids, phenolic acids and eleutherosides in a 70 % water-alcohol extract from E. senticosus dry leaves at different phases of vegetation period. The spectra were recorded using an Agilent Cary 60 UV-Vis spectrophotometer. Moreover, the content of extractive substances was determined, and the content of vitamin C, and β-carotene in fresh leaves (State Pharmacopoeia 2015).Results:The results of our study showed that levels of phenolic compounds in the leaves of E. senticosus obtained in hydroponics and soil culture are the highest during the flowering phase (August-September). It was observed that during the flowering period, the content of total phenols, phenolic acids, and eleutherosides was 1.3 times higher, and flavonoids - 1.2 times higher compared to the vegetative phase. It is worth noting that the content of vitamin “C”, β-carotene and extractives was also higher during the flowering period. Hydroponic plants had higher content of vitamin “C”, β-carotene, and extractives, respectively by 1.4, 1.2 and 1.2 times compared to soil plants. This could be due to several factors such as the optimal content of nutrients (N=200 mg/L, P=65 mg/L, K=350 mg/L), and the high content of oxygen in the hydroponic system. Conclusion: According to the results of a phytochemical study of E. senticosus leaves grown in outdoor hydroponics and soil culture in the Ararat Valley, the highest content of biologically active compounds (eleutherosides, phenols, phenolic acids, vitamins) is recorded in hydroponic plants in the flowering period. In general, the research has practical importance,sin","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"150 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135933425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perch essence prevents cell death to improve skeletal muscle mass and strength: Evidence from in vitro and human model","authors":"Chih-Cheng Lin, Chih-Yu Hsieh, Ling-Ni Chen, Mao-Hsiang Lee, Yi-Han Ting, Ting-Ming Wang, Jia-Feng Chang","doi":"10.31989/ffhd.v13i10.1177","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1177","url":null,"abstract":"Background:Fish protein supplementation may maintain muscle strength and prevent sarcopenia as it contains a complex array of macro- and micronutrients essential for building the skeletal muscle. Objective:The aim of this study was to evaluate the influence of perch essence (PE) supplementation on muscle mass and muscle function of through human and cell model. Methods:The open label clinical trial was conducted to assess the therapeutic effect of PE on muscle mass improvement. The mouse skeletal muscle cell (C2C12) model of muscle atrophy was analyzed for cell viability. Results:Our results showed PE contained abundant branched chain amino acid, taurine, hydroxyproline and collagen. After one month of supplementation with PE in our human model, there was a significant increase in muscle mass in the whole body and all parts of the body, with an increase of 1.55 % in the whole body, 1.79% in the trunk, 1.64% in the arms and 1.38% in the legs. The percentage of subcutaneous fat in the trunk, arms and legs also decreased significantly by 2.49%, 3.21% and 3.40% respectively. PE supplementation also improves muscle grip strength, especially with the dominant hand. The cell model results demonstrated that PE could effectively prevent skeletal muscle cell from death induced by dexamethasone. Conclusion:This study suggests that the branched chain amino acids, taurine, hydroxyproline and collagen in PE have the potential to serve as a good source of dietary supplements for the improvement of skeletal muscle mass and strength through cell protection.Keywords:branched chain amino acid, collagen, perch, skeletal muscle, sarcopenia","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"15 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136105158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional Value of Soybean under Outdoor Hydroponics and Soil Conditions of the Ararat Valley","authors":"Artur Matevosyan, Anna Tadevosyan, Anahit Tovmasyan, Armenuhi Asatryan, Stepan Mairapetyan","doi":"10.31989/ffhd.v13i10.1208","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1208","url":null,"abstract":"Background: Population growth increases the demand for food all over the world. According to the Food and Agriculture Organization of the United Nations, by 2050 the world population will reach 9.1 billion people, for whom food production is expected to increase by 25-70 %. That will lead to an increase in the demand for alternative farming technologies allowing us to ensure higher yields in less time. One such alternative and highly profitable plant growing technology is soilless culture or hydroponics. Climate change, improved technological capabilities, and need to increase self-sufficiency are good reasons for the introduction of soybean in Armenia.Soy, as one of the richest and cheapest sources of protein, plays an important role in the diet of people in many countries. The seed of soybeans contains 17 % oil and about 50 % protein. Because soybeans contain no starch, they are a good source of protein for diabetics.Objective: To establish the possibility and efficiency of soybean cultivation in Ararat Valley by traditional agricultural method and by the regulated hydroponic system and to investigate the nutritional value of soybean seeds.Results: The cultivation method had some influence on soybean yield and on the biosynthesis of several nutritional components. Thus, soilless culture conditions contributed to the increase in soybean yield: the weight of seeds obtained from one plant was 38.7 g while in the soil it was only 19.9 g. Soil plants were distinguished by the maximum accumulation of fat (28.9 %), while hydroponic ones by the maximum content of protein (31.5 %) and sugar (6.3 %).Conclusion: The obtained results established the effectiveness of soybean cultivation in Armenia. The regulated hydroponic method ensures obtaining about 11.6 tons ha-1 of soybean seeds, 3.7 tons ha-1 of protein and 2.6 tons ha-1 of fat. The work was supported by the Science Committee of the Republic of Armenia, in the frames of the research project N 21T-4B167.Keywords: Glycine max (L.) Merr., soilless culture, proteins, fats, sugars","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"3 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136376115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of theobromine content and the relationship between cocoa percentages in dark chocolates","authors":"Fatma Hulyam Eren, Seray Kabaran","doi":"10.31989/ffhd.v13i10.1141","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1141","url":null,"abstract":"Background: There are no specific regulations governing the labeling of dark chocolate or its bioactive component quantities.. The main alkaloid of the cocoa bean is theobromine. Chocolate is by far the main source of theobromine in the Western diet. To assess their effects on health, it is essential to understand the ingredients and composition of biologically active substances in chocolates available in stores.Objective: The present study aims to analyze the theobromine contents of commercial chocolates and evaluates the association between the labeled cocoa mass percentage (%), theobromine contents and evaluated non-fat cocoa solid (NFCS) parameters of dark chocolates. Materials and Methods: Several types of chocolates (bittersweet dark [60-80% cacao], semisweet dark [45-50% cacao], milk chocolate, and chocolate spreads) were analyzed using UV-Vis spectrophotometry with duplicate measurements.. Samples (n=20) typically 6 months apart from production dates have been selected. Results: Overall range for theobromine content varied from 1.9 to 9.6 mg/g. Of all, bittersweet dark chocolate had the highest (8.1±1.01 mg/g) concentration of theobromine in comparison to semisweet dark chocolate (6.4±0.79 mg/g). Milk-chocolate (2.7±0.26 mg/g) and chocolate-spreads (2.7±0.81 mg/g) had the lowest concentration of theobromine. A strong correlation between theobromine content and declared cocoa solid % was found in both of the dark chocolate categories (r = 0.523, p = 0.081 and r = 0.771, p = 0.009 for semisweet and bittersweet dark chocolate, respectively). NFCS indicated a correlation between the labeled cocoa solid % (R2 = 0.766) and the calculated cocoa solid % (R2 = 0.803) in dark chocolates. A high correlation has also been determined between the labeled cocoa solid percentage and the calculated cacao solid percentage in dark chocolates (R2 = 0.902).Conclusion: The labeled content of the cocoa mass of dark chocolates could be a preliminary information for the consumer about theobromine capacity.Keywords: Theobromine, chocolate, dark chocolate, cocoa-percentage, UV-Vis spectrophotometry","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"28 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135265856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking the potential of carrot pomace: Enzymatic and impact-disintegrator-activator processing for elevated beta-carotene concentration in carrot powder","authors":"Angelina Baskovtceva, Nadezhda Barakova, Evgeniy Samodelkin, Elena Kiprushkina, Reem Alkhateeb, Grigory Tochilnikov","doi":"10.31989/ffhd.v13i10.1184","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1184","url":null,"abstract":"Backgrounds: Carrot pomace is a by-product of the juice industry, which quickly spoils due to its high moisture content and is usually considered waste. However, it is a valuable product containing a significant amount of bioactive compounds, particularly carotenoids.Context and purpose of this study:In this study, we aimed to develop a technology for obtaining carrot powder from carrot pomace with an increased availability of beta-carotene. The unique aspect of the technology involved the use of enzymatic and impact-disintegration-activation processing (IDAP) of the raw material to enhance the release of beta-carotene from plant cells.Objective of this study:To achieve the goal, we have set objectives to compare various dosages of enzyme preparation and to evaluate devices for grinding carrots that can be used to make powder. At all stages, it was necessary to measure the amount of beta-carotene in the samples.Results: It has been found that the yield of carotenoids from carrot pomace is 185% higher compared to whole carrots. Moreover, the application of enzymatic and impact-disintegration-activation processing significantly increases the carotenoid yield in the powder by 17 times compared to carrots (200% in terms of dry matter). This remarkable result was achieved through the described processing method and the selection of the enzyme preparation. Additionally, the mechanoactivation obtained by using the Desi-15 disintegrator played a crucial role. It was also observed that the use of impact-disintegration-activation processing for further grinding of dried carrots can increase the beta-carotene yield by 8 times. Conclusions: The carrot pomace was processed, resulting in a fine-dispersed carrot powder that shows promising applications in the food or agricultural industries.Keywords: Carrot pomace, beta-carotene, impact-disintegrator-activator processing (IDAP), enzymatic processing, pectolytic enzyme preparations","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"1 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135366282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation of a novel gallotannin-enriched Galla Rhois extract (GRE) on vital cognitive functions in healthy volunteers: A randomized, double-blind, placebo-controlled study","authors":"Marvin Heuer, Christopher Baker, Michael Sedlak, Kim Jin Woo, Kim Hyun Kee, Debasis Bagchi","doi":"10.31989/ffhd.v13i10.1213","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1213","url":null,"abstract":"Background: Oxidative damage has emerged as one of the significant factors in the onset of neurodegenerative disorders, primarily owing to a) higher usage of oxygen by brain cells and b) higher amounts of lipids in the neuronal membranes. Together, these have resulted in higher susceptibility of brain cells to ROS-induced lipid peroxidation, damage to other cellular macromolecules, including nucleic acids and proteins, and death of neurons by apoptosis, ferroptosis, and necrosis. The design of therapeutics to prevent oxidative damage-induced brain stroke or other irreversible injuries has remained a challenge owing to the continuous production of free radicals at the site of damage. In this respect, plant-derived tannins and tannic acid derivatives have exhibited promising results in scavenging free radicals and inhibiting lipid peroxidation.Objective: This investigation reports the effect of Ghala Rois extract (GRE), a methyl gallate enriched gall formed on the nutgall sumac tree, Rhus javanica L. (Anacardiaceae), on enhancing the cognitive function and overall well-being through a double-blind, placebo-controlled, randomized, parallel-group design study on 80 healthy adult volunteers over a period of six consecutive weeks.Results: Administration of GRE in the dosage of 750 mg/day p.o. (with an equal amount of corn starch as a placebo) after breakfast resulted in significant improvement in cognitive functions as assessed by HappyNeuroPro, a digital therapy tool, and the cognitive tools under Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MOCA) and Adult ADHD Self-Reported Scale (ASRSv1.1). Concomitantly, the GRE-treated subjects also scored significantly higher (p = 0.033) in the roles of Physical and Emotional Problems, Energy/Fatigue, Emotional well-being, and pain as evaluated by linearly independent pairwise comparisons among the estimated marginal means and computed using alpha = 0.05. In the Global Evaluation Questionnaire, over 77% of the treated subjects believed that the product increased their attention span, and helped their memory by 70%, and they also indicated their willingness to buy the commercially available GRE. Evaluation of the complete metabolic profile in the GRE-treated subjects significantly lowered the blood urea nitrogen (BUN) (11.98 mg/dL) as compared to placebo (13.27 mg/dL) (p = 0.011) as well as SGPT/ALT from 28.09 U/L (placebo) to 18.17 U/L (GRE-treated) (p<0.001). However, the vital parameters, including heart rate and systolic/diastolic pressure, were not affected by the consumption of GRE extract.Conclusion: The study demonstrated that GRE could be used as an effective new phytotherapeutic for reversing oxidative damage-induced neuronal degeneration and improving cognitive health in these study individuals.Keywords: Galla Rhois extract (GRE); Rhus javanica L. (family Anacardiaceae); Cognitive functions; ADHD; Executive function; Verbal memory; Safety, Reactive Oxygen Species (ROS)","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"31 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135567623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The possible anti-inflammatory properties of hydro-ethanolic extract of Oregano","authors":"Armenuhi Moghrovyan, Mikayel Ginovyan, Nikolay Avtandilyan, Lilya Parseghyan, Armen Voskanyan, Naira Sahakyan, Anna Darbinyan","doi":"10.31989/ffhd.v13i10.1211","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1211","url":null,"abstract":"Backgrounds: Plant compounds are of great value due to their analgesic, anti-inflammatory, cytotoxic, and other characteristics. This study aimed to examine the chemical composition and impact of the Origanum vulgare hydro-ethanolic extract on nociceptive behavior and anti-inflammatory properties in in vivo mice models.Methods: Gas chromatography-mass spectrometry and high-performance liquid chromatography techniques were employed to determine the major active phytochemicals of the extract. The effects of the extract on nociceptive reactions were evaluated using formalin and hot plate tests, while the anti-inflammatory effect was determined using the Carrageenan test. The methyl-thiazolyl-tetrazolium assay was applied to analyze growth-inhibiting properties of the extract on MCF-7 breast cancer cells.Results: Various flavonoids and organic acids were identified in O. vulgare hydro-ethanolic extract. The extract possessed low cytotoxicity on MCF-7 cells as only 1 mg/mL or higher concentrations of the extract induced considerable growth inhibition. The formalin and hot plate tests demonstrated some sensitizing effects of the investigated extract (5 mg/kg) on mice. Moreover, the Carrageenan test revealed pronounced anti-inflammatory properties of the O. vulgare extract.Conclusion: The potent biological activity of the wild oregano herb extract makes it a promising source for the development of medicinal preparations. Keywords: Nociceptive behavior, anti-inflammatory effect, Oregano, flavonoids, chemical composition, cytotoxicity, in vivo mice models.","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"2011 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134973532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alleviating the physical discomfort in healthy individuals with Moringa seed extract: a randomized, double-blind, placebo-controlled, parallel-group trial","authors":"Aya Abe, Mahendra P. Kapoor, So Morishima, Derek Timm, Atsushi Nakajima, Makoto Ozeki, Norio Sato","doi":"10.31989/ffhd.v13i10.1142","DOIUrl":"https://doi.org/10.31989/ffhd.v13i10.1142","url":null,"abstract":"Background: Moringa oleifera is well recognized for its rich nutritional content and diverse bioactive compounds. Moringa, abundant in various bioactive compounds such as flavonoids and alkaloids present across all plant parts including leaves, stems, and roots, is especially rich in glucomoringin within its seeds. The antioxidant activity of moringin has already been verified in numerous cellular and animal experiments.Objective: The study investigates the effects of Moringa seed extract (MSE), abundant in glucomoringin, on fatigue-related physical discomfort and sleep quality, as indicators of quality of life (QOL) in healthy individuals.Methods: A randomized, double-blind, placebo-controlled, parallel-group study was conducted, administering MSE containing 12 mg of glucomoringin or placebo to healthy adult males and females daily for four consecutive weeks. Quality of life (QOL) questionnaire on fatigue, physical discomfort, sleep, and motivation was evaluated using a visual analog scale (VAS) at the start of the study and the end of each subsequent week until week 4. The impact on QOL was assessed through subjective evaluations and oxidative stress markers.Results: As a result, the efficacy of MSE intake in reducing stiff shoulder/neck pain, joint pain, and muscle pain was confirmed. Based on the oxidative stress markers, significant effects were observed among the participants with relatively high oxidative stress. A greater improvement in physical discomfort, reduced fatigue, and enhanced sleep quality were also noticed among female participants with MSE consumption. Conclusion: MSE consumption has showed potential in lowering physical discomfort brought on by exhaustion, promoting overall QOL, and improving sleep quality. (UMIN000049070)Keywords:moringa; moringin; glucomoringin; physical discomfort; sleep quality; fatigue; pain","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135590574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reproductive health-promoting effects of functional foods","authors":"Omowumi Kayode, Nkechinyere J. Ohanaka, Ikeoluwa O. Kolawole, Olatayo A. Afolabi, Matthew E. Iyobhebhe","doi":"10.31989/ffhd.v13i9.1130","DOIUrl":"https://doi.org/10.31989/ffhd.v13i9.1130","url":null,"abstract":"Functional foods are foods that, in addition to providing basic nutrients, have health-promoting effects when ingested consistently over a period of time. These foods can exist in their natural forms or might have been enhanced through fortification, biotransformation, or genetic modification. Globally, a lot of attention has been drawn to its consumption as a cheaper and safer remedy for the prevention, treatment, and management of several health-related conditions, including those of reproductive difficulties such as infertility. Infertility is a condition that is prevalent among some married couples and involves difficulty in procreation after about twelve months of unprotected intercourse between heterosexual couples. Oxidative stress-related infertility can be managed by functional foods rich in antioxidants and other phytochemicals with modulatory effects on reproductive tissues. Consumption of prescribed functional foods can alleviate functional disorders of the reproductive tissues and hence encourage higher success rates at conception trials.Keywords: functional foods, reproductive, infertility, health, antioxidants","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135534753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}