A. Tadevosyan, A. Hakobjanyan, A. Tovmasyan, A. Asatryan, H. Roosta, M. Daryadar
{"title":"Hypoglycemic and hypolipidemic activity of moringa grown in hydroponics and soil in Ararat Valley","authors":"A. Tadevosyan, A. Hakobjanyan, A. Tovmasyan, A. Asatryan, H. Roosta, M. Daryadar","doi":"10.31989/ffhd.v13i8.1158","DOIUrl":"https://doi.org/10.31989/ffhd.v13i8.1158","url":null,"abstract":"Background: Moringa has a hypoglycemic and hypolipidemic influence, and the water extract of its leaves can decrease the amount of glucose during Diabetes Mellitus. Moringa leaves in extract or powder form influenced type I and type II diabetes by enhancing insulin secretion and improving glycogen synthesis and glucose uptake in the liver and muscles. This occurred in the case of type I diabetes, as well as by inhibiting glucose uptake and slowing gastric emptying in the case of type II diabetes.Objective: In our study, we try to evaluate the hypoglycemic, hypolipidemic, and antistress activity of Moringa grown for the first time in Armenia in hydroponic and soil conditions to find out the beneficial cultivation method of Moringa from the point of view of these activities.Materials and Methods: The study was done with the usage of a rabbit model, using water extract of Moringa leaves made with a 150 mg count of leaves on 1 kg weight of the animal. Hyperglycemia in the rabbits was induced by 21-day immobilization stress (3 hours a day). Rabbits were divided into 4 groups: the first group was treated with the extract from the hydroponic Moringa in a dose of 2 ml/day, the second group received the extract from the soil Moringain a dose of 2 ml/day, the third group was the control—which did not receive any extract, but was exposed to stress, like first and second groups— and the fourth group was the norm, which did not receive any extract and was stress free. Each group included 3 animals as means of replication. The glycogen level was measured in the livers, hearts, and muscles of rabbits. The level of glucose, total cholesterol, HDL, and LDL were measured in the serum of animals.Results: Our results showed that after a 21-day period of stress, the increased level of glucose stays at a high level in control groups, while the use of a hydroponic Moringa extract developed stress tolerance in animals and in soil Moringa extract stabilizes glucose levels in the blood. The cholesterol exceeded the norm 1.8 times in the control group and was inferior in hydroponic and soil groups by 1.5 and 1.4 times, respectively. These changes reflect the amount of HDL and LDL. Under stress conditions, the quantity of glycogen decreased from the norm in the liver, muscles, and heart muscle in the control group (2.5; 2.4; and 2.4 times, respectively) and increased in hydroponic (1.6; 1.5; and 2.1 times, respectively) and soil (1.6; 1.5; and 2.4 times, respectively) groups. This evidence shows that under stress conditions the glucose level of blood is improved on the 21st day of stress in groups that received the extract of moringa because of glucose exchange to glycogen with high efficiency in different organs.Keywords: antistress activity, diabetes, HDL, glucose, Moringa oleifera, total cholesterol","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43145192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Hadi, D. Shaban, M.A.H. Morgab, Safa Mohammed Jasim
{"title":"Chemical composition and effective compounds of dates and their use in a snack to give energy to athletes","authors":"S. Hadi, D. Shaban, M.A.H. Morgab, Safa Mohammed Jasim","doi":"10.31989/ffhd.v13i8.1147","DOIUrl":"https://doi.org/10.31989/ffhd.v13i8.1147","url":null,"abstract":"Background: Dates are recognized as a rich source of nutrients, so they are considered a complementary food element positioning them as functional food for athletes. Energy balls are nutritious snack foods that people, individuals and athletes enjoy. They are a source of natural sugars, fibers and proteins that are nutritionally balanced. Food supplements consist of protein, fats, vitamins, minerals and carbohydrates. Objective:Enrichment some food products, especially energy-rich balls for athletes that made from dates as a main component for it. Materials and Methods: Date fruits from five cultivars (Dekel Nour, Barhi, zahdi, khlas, sukari) were collected from the orchards of Baghdad Governorate. The fruits were cleaned and dried in an oven at a temperature of 45 ° C until dryn, then the fruits were ground by means of a grinder. The ground forms were kept in sealed glass containers at a laboratory temperature of 20-25 °C until use.Results: Variability in contents was observed across the different cultivars, with the highest percentage of total sugars, amounting to 86.70%, being recorded in Barhi dates. Conversely, the lowest sugar percentage was found in date meat, measuring at 69.20%. The fruits recorded the highest moisture percentage with a value of 30.01%. The mineral composition showed that P was the predominant mineral, followed in descending order by Mg, Ca, and proteins. The protein content ranged from 2.14 to 3.20%, while crude fat ranged from (0.15 - 0.44) %. Moisture content in date varieties with early ripening time was between low and high values of 10% to 30%. The comprehensive nutritional profile encompassed minerals and numerous vitamins, most notably B vitamins. Carbohydrates constitute 70% of the date’s composition, including fructose and glucose. Additionally, dates are rich in calcium, magnesium, selenium, copper, phosphorous, potassium, zinc, sulfur, cobalt, fluorine, and manganese. Lately, interest in dates has increased because of their health importance, catalyzing the development of food products.Keywords: Dates, active substances, chemical compounds, functional foods, oat, nuts","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47739541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Daryadar, J. Alexanyan, Stepan K. Mayrapetyan, Kh.S. Mayrapetyan, A. Tovmasyan, A. Tadevosyan
{"title":"Estimating peppermint essential oil levels: water-stream and classical hydroponic systems","authors":"M. Daryadar, J. Alexanyan, Stepan K. Mayrapetyan, Kh.S. Mayrapetyan, A. Tovmasyan, A. Tadevosyan","doi":"10.31989/ffhd.v13i7.1123","DOIUrl":"https://doi.org/10.31989/ffhd.v13i7.1123","url":null,"abstract":"Background: The leaves of peppermint and the essential oil received from them are used in medicine. The chemical content of essential oil is quite complex. It contains about 30 terpene compounds. The content of essential oil in flowers is 4-6%; in leaves – 2.4-2.8%, and in stems 0.3%. The main components that define the quality of essential oils are menthol, menthone, limonene, menthofuran, and isomenthone. Peppermint is used in the form of tea, tincture, extract, and salves. It has a regulating influence on the heart and circulatory system. It calms the heartbeat and supports the decrease of blood pressure, and the oil stream is used for dyspnea in the form of inhalation. Plant cream is used against insect bites, eczema, hemorrhoids, muscle pains, and some chronic diseases.Context and purpose of this study: The work aimed to study the content of the main components from the quality indicators of the essential oil of peppermint grown in different water-stream and classical hydroponic systems for the first time in Armenia.Results: From the analyses, it was revealed that the strengthening of the essential oil of peppermint grown in different systems of the water-stream hydroponics (cylindrical, gully, continuous) and classical hydroponics was observed in August. At the same time, high-yield plants of cylindrical and classical hydroponic systems exceeded other variants by 1.3-1.5 times with the essential oil output. In hydroponic systems, the specificities of the physical-chemical indices of peppermint essential oil were also studied. In August, the refractive indicator of essential oil increased to some extent in all variants, except for continuous hydroponics. The lack of increase in continuous hydroponics can likely be explained by the change in the ratio of essential oil to different compounds. At the end of vegetation, in September, some increase of essential oils' specific gravity was observed in the gully (2.1-3.5%) and continuous (4.5-4.7%) modules, while in cylindrical and classical hydroponics the change was minor. During vegetation, the essential oil of plant leaves was subject to not only quantitative but also qualitative changes. The cylindrical system exceeded other water-stream hydroponics variants with the main essential oil menthol component by 1.1-1.4 times and classical hydroponics by 1.1 times. The Gully system exceeded other water-stream systems with the content of D-Limonene and Menthyl acetate 3.6-9.7 and 1.3-3.0 times, respectively. And classical hydroponics 1.4 and 1.7 times, respectively. In the continuous system, the content of Isomentone, Pulegone, and Mint furanone was 1.3-2.0, 3.3-3.5, and 5.7-6.2 times higher, respectively, compared with the other water-stream hydroponic systems, and 1.6, 2.6, and 1.7 times, compared with classical hydroponics. Classical hydroponics exceeded all variants of water-stream hydroponics in the content of Piperidone by 3.3-4.1 times.Conclusion:Although the strengthening of essential oil bios","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41656723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Food and medicinal plants from Nigeria with anti-Helicobacter pylori activities induce apoptosis in colon and gastric cancer cell lines","authors":"T. Lawal, Shital R Patel, G. Mahady","doi":"10.31989/ffhd.v13i7.1105","DOIUrl":"https://doi.org/10.31989/ffhd.v13i7.1105","url":null,"abstract":"Background: Food and medicinal plants are used traditionally in Nigeria to treat gastrointestinal (GI) disorders such as gastritis, peptic ulcer disease and GI-related cancers. We have previously reported that specific extracts of Nigerian food and medicinal plants inhibited the growth of Helicobacter pylori, a bacterium known to cause peptic ulcer disease, as well as gastric and colon cancer. Objective: To determine the effects of three food plants, namely Anogeissus leiocarpus (DC.) Guill. & Perr. (African birch, Combretaceae), Terminalia glaucescens Planch ex Benth. (Nigerian chewing sticks, Combretaceae) and Dillenia indica L. (Elephant apple, Dilleniaceae) used in Nigeria for the treatment of GI disorders and cancer in six colon and gastric cancer cell lines, and two non-cancerous cell lines. Methods: Cancer cells were grown in appropriate media and CellTiter-Glo® 2.0 and ApoTox-Glo™ Triplex assays were used to measure cell growth and apoptosis in SW480, SW620, HCT116, Caco2 cell lines, as well as AGS and NCI-N87 gastric cancer cells. Caspase-Glo® 3/7, and Caspase-Glo® 8 were used to determine caspase activities and apoptosis. Gene expression was measured using quantitative PCR.Results: The methanol extract of A. leiocarpus roots inhibited the growth of HCT-116, SW480 and SW620 colon cancer cells (IC50 of 15.8, 10.0, and 20.8 µg/mL, respectively), but weakly active in the AGS and NCI-N87 cells (IC50 77.0 and >100 µg/mL respectively). The T. glaucescens extract was weakly active in HCT-116 cells (IC50 64.9 µg/ml) and AGS cells (52.2 µg/ml). The D. indica extract was active in SW480 (IC50 15.8 µg/mL), and weakly active in Caco2 (IC50 35.2 µg/mL) and HCT-116 (IC50 53.2 µg/mL). In HCT-116 cells, A. leiocarpus root extract and its aqueous partition increased caspase 8 activity, as well as mRNA expression of p53, while expression of Bcl-2 and HDAC1 mRNA was reduced. Bioassay guided fractionation of the aqueous partition led to the isolation and identification of the known compound methyl gallate.Conclusions: These data suggest that the Nigerian food plants with anti-Helicobacter pylori activities increase the expression of the tumor suppressor p53 and inhibit HDAC1, thereby inducing apoptosis in HCT-116 colon cancer cells.Running Title: Inhibitory Effects of Nigerian food plants on GIT CancersKeywords: African birch, AGS, Apoptosis, Anogeissus leiocarpus, Dillenia indica, Elephant apple, Terminalia glaucescens, Nigerian chewing sticks, HCT-116, SW480, SW620","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48144379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Abitayeva, G. Bissenova, B. Mussabayeva, Yerassyl Naimanov, Тamara Тultabayeva, Z. Sarmurzina
{"title":"Development, quality and safety evaluation of a probiotic whey beverage","authors":"G. Abitayeva, G. Bissenova, B. Mussabayeva, Yerassyl Naimanov, Тamara Тultabayeva, Z. Sarmurzina","doi":"10.31989/ffhd.v13i7.1121","DOIUrl":"https://doi.org/10.31989/ffhd.v13i7.1121","url":null,"abstract":"Background: This study was aimed at the development of a whey beverage enriched with a probiotic starter culture, prebiotics, vitamins, and minerals, and evaluation of microbiological, physico-chemical, and toxicological characteristics of the developed beverage.Methods: The beverage formulation was determined based on organoleptic analysis. The assessment of microbiological and physico-chemical parameters was carried out in accordance with regulatory standards. The safety assessment of the developed drink was carried out in vivo.Results:A beverage formulation based on whey enriched with probiotic bacteria Lactobacillus casei 1A, Lactobacillus paracasei 2A, Lactobacillus brevis 4 LB, prebiotic inulin, vitamins (A, C) and minerals (potassium iodide) was developed. The organoleptic, physico-chemical, and microbiological properties of the developed drink were determined. The quality of the beverage complied with food safety regulations, the viability of probiotic bacteria and the acidity of the beverage remained stable during storage. Acute score toxicity and allergenic properties in vivo did not reveal any physiological abnormalities and made it possible to classify the developed product as a low-hazard substance.Conclusion:The optimal composition of a probiotic whey beverage has been developed, which can be considered as a potential product for functional nutrition.Keywords: Whey beverage, Formulation, Probiotic, Functional, Safety Assessment, Toxicity, Allergenic properties, In vivo","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46078059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Youovop, G. Takuissu, Christelle Mbopda, F. Nwang, Raissa Ntentié, Mary-ann A. Mbong, B. Azantsa, Harinder Singh, J. Oben
{"title":"The effects of DyglomeraⓇ (dichrostachys glomerata extract) on body fat percentage and body weight: a randomized, double-blind, placebo-controlled clinical trial","authors":"J. Youovop, G. Takuissu, Christelle Mbopda, F. Nwang, Raissa Ntentié, Mary-ann A. Mbong, B. Azantsa, Harinder Singh, J. Oben","doi":"10.31989/ffhd.v13i6.1088","DOIUrl":"https://doi.org/10.31989/ffhd.v13i6.1088","url":null,"abstract":"Introduction: Previous studies have shown the beneficial effects of Dyglomera®, a hydroethanolic extract of Dichrostachys glomerata, on inflammation as well as parameters linked to metabolic syndrome. Its effect on body fat was however not verified. The present study was therefore carried out to evaluate the anti-obesity effect of the Dyglomera®, on overweight and obese subjects.Methods: This 12-week randomized, double-blind placebo-controlled trial had percentage body fat measured by dual-energy X-ray absorptiometry, body weight and body mass index set as efficacy endpoints. On the other hand, key biochemical parameters were measured as secondary endpoints. The values of these parameters at T12 compared to T0 for the placebo and Dyglomera® groups were used as a measure of the efficacy. Results: Subjects treated with Dyglomera® for 12 weeks showed significant differences, with 6.73 kg (p<0.05) decrease in the body weight and 22.85% (p<0.05) reduction in the percentage body fat. In addition, the markers of lipid profile, adipocytokines, glycemia and transaminases plasmatic activities were also improved by the intake of Dyglomera®.Conclusions: This study shows that Dyglomera® effectively decreases the body weight in obese subjects after 12 weeks of treatment, which was accompanied by a reduction in the body fat and related disorders. Dyglomera®is a good agent for overweight and obesity management.Keywords: Dichrostachys glomerata, Dyglomera®, body fat percentage, body weight, clinical trials.","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45352788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahraa Adil Ahmed, N. K. Mohammed, A. S. Meor Hussin
{"title":"Acrylamide content and quality characteristics of French fries influenced by different frying methods","authors":"Zahraa Adil Ahmed, N. K. Mohammed, A. S. Meor Hussin","doi":"10.31989/ffhd.v13i6.1126","DOIUrl":"https://doi.org/10.31989/ffhd.v13i6.1126","url":null,"abstract":"Background: This study aimed to compare the effects of three different frying methods, namely air frying (AF), microwave frying (MF), and deep frying (DF) in corn oil, on the moisture and texture, as well as the content and absorption of oil, carbohydrates and acrylamide in French fries. Materials and Methods: For the DF, the fresh potatoes were fully dipped in corn oil and the oil temperature was set at 160 °C for three intervals of 3, 5, and 7 minutes. In the MF, the oil was preheated to 180 °C for three time intervals of 160, 180, and 200 seconds. The AF was set at a temperature of 170 °C for three time intervals of 8, 10, and 12 minutes, without adding oil.Results: The results showed that AF resulted in a lower acrylamide content (21.8 ppm) after 8 minutes at 170°C compared to the other frying methods. However, DF in corn oil was preferred in terms of color, flavor, and overall acceptance in the sensory evaluation of the French fries. MF resulted in the hardest French fry texture due to excessive evaporation of moisture.Conclusion: The findings suggest that AF may be a healthier option with a lower acrylamide content, while DF in corn oil may be preferred for its superior sensory characteristics.Keywords: Acrylamide, Air frying, Deep frying, Microwave, Oil absorption, Sensory evaluation. ","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43094028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacokinetic effect of Astragalus membranaceus and Panax notoginseng saponins on arginine absorption and nitric oxide production in healthy subjects","authors":"Ching-Pin Lin, Chao Lin, I-Chin Wu, Tingtiao Pan, You-Cheng Shen","doi":"10.31989/ffhd.v13i6.1104","DOIUrl":"https://doi.org/10.31989/ffhd.v13i6.1104","url":null,"abstract":"Background: To the best of our knowledge, there are no clinical trials conducted with Astragalus and ginseng extracts on nitric oxide (NO) levels in humans. Therefore, this study aimed to examine whether the standardized intake of Astragalus membranaceus and Panax notoginseng saponins (APS) could increase NO production by enhancing arginine absorption and reducing levels of asymmetric dimethylarginine (AMDA).Methods: A clinical trial involving healthy adult participants aged between 20 to 80 years was conducted as a randomized, double-blind, cross-over study. The participants received 5 g of arginine powder and one capsule of APS or placebo twice, with a wash-out period between each administration. Plasma and urine were collected for testing, and 24 subjects were included for analysis after excluding six subjects with great individual differences.Results:It was found that after APS supplementation, the area under the curve (AUC) of arginine significantly increased by 17.3% (p = 0.041), the maximum concentration (Cmax) increased by 11.1%, and the Arg/ADMA ratio significantly increased by 167.1% (p = 0.007). Moreover, urinary nitrate and cGMP levels increased by 20.8% and 18.9%, respectively.Conclusions: APS showed increases in arginine absorption, decrease ADMA levels, and enhance NO production. With these findings, the addition of APS to arginine supplements could be advantageous for pre-workout and cardiovascular health.Keywords:Astragalus membranaceus and Panax notoginseng saponins (APS), arginine, asymmetric dimethylarginine (ADMA), nitric oxide (NO), cyclic guanosine monophosphate (cGMP)Clinical trial registration: NCT05024123","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41762530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of sulforaphane glucosinolates from broccoli seed extract on the immune system of healthy Japanese adults","authors":"Naoyuki Kouno, N. Suzuki, T. Takara","doi":"10.31989/ffhd.v13i6.1089","DOIUrl":"https://doi.org/10.31989/ffhd.v13i6.1089","url":null,"abstract":"Background: The Purpose of this study was to investigate the effects of sulforaphane glucosinolate (SGS) from broccoli seed extracts on immune function and common cold symptoms in healthy Japanese adults.Methods: This randomized, placebo-controlled, double-blind, parallel-group comparison study was conducted on Japanese adults who had worse health-related quality of life on the SF-8 and were more likely to catch colds from October 22, 2020 to April 2, 2021.Individuals who agreed to participate in the study were randomly assigned to either the SGS 100 mg/day group or the placebo group (n = 33 each). The intervention lasted 8 weeks. The outcomes of this study were the cumulative and the maximum number of days for which common cold symptoms persisted during the intervention period per subject (primary), and the frequency with which subjects experienced these symptoms per group (secondary). Additionally, the incidence rate of subjects infected with the influenza virus, immune indices, and SF-8 were assessed.Results: Based on a per protocol set, 64 subjects (33 in the SGS group and 31 in the placebo group) were analyzed. After the 8-week interventional period, the cumulative number of days for which common cold symptoms per subject was significantly lower for the SGS group than the placebo group (12.1 ± 13.5 for the SGS group and 20.2 ± 18.2 for the placebo group). The cumulative number of days of common cold symptoms per group was also significantly lower in the SGS group than in the placebo group (400 days in the SGS group and 626 days in the placebo group). No changes attributable to the SGS intervention were observed in the other outcomes. There were no adverse events due to food ingestion.Conclusion: A period of 8 weeks of SGS intake was shown to alleviate the onset of common cold symptoms in healthy Japanese adults who were prone to catching colds and had a low subjective sense of wellness.Keywords: Broccoli, sulforaphane, glucoraphanin, cold symptoms, immunityTrial registration: UMIN-CTR: UMIN000042195.Foundation: Murakami Farm Co., Ltd.","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48336847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hrachya Tspnetyan, Elya S. Pepoyan, A. Pepoyan, Syuzanna Abrahamyan
{"title":"Marketability level of potato in Armenia: potato functional properties","authors":"Hrachya Tspnetyan, Elya S. Pepoyan, A. Pepoyan, Syuzanna Abrahamyan","doi":"10.31989/ffhd.v13i5.1103","DOIUrl":"https://doi.org/10.31989/ffhd.v13i5.1103","url":null,"abstract":"Background: Functional food is becoming more and more important for professionals and also for consumers. On the other hand, it is known that the main factors affecting the sale of agricultural products are the general market dynamics, legislation, product range, seasonal sales dynamics, competitors, pricing, buyers and distribution channels. What’s also important is the profile of the company's personnel and the work of personnel in the market, advertising related to the quality of the product, which in recent times is especially based on the \"natural\" origin and functional value of the product․ Objective: The aim of the current study is to quantify the factors influencing the level of potato marketability through econometric analysis in Armenia. One of the objectives was also to observe whether the population appreciates the functional value of potatoes, which may affect future marketability and yield of potatoes. Methods:Quantitative assessment of the factors influencing the level of potato marketability was carried out with a number of indicators: the yield of the sowing area, the gross harvest and the volume of export and import. Observations were carried out during 10 years (2009 - 2018). A seven-item questionnaire was developed to explore consumer preferences for purchasing potatoes. Results:The level of marketability of potatoes had an increasing trend with the certain fluctuations (years: 2010, 2014, 2016 and 2018). The data on the correlation coefficients on the factors influencing the level of potato marketability indicated that the relationship between the marketability level and potato planting area is inverse to the average level (ryx1 = - 0.615). The correlation between the level of commerciality and yield is direct in the lower middle range (ryx2 = 0.461). The latter shows that increasing the level of yield contributes to the level of marketability. The effects of gross harvest, export and import volumes have a negative impact on the level of commoditization, but the relationship is extremely weak with ryx3 = - 0.214 and ryx4 = - 0.0532 and ryx5 = - 0.105. Interview studies show that factors affecting potato marketability and productivity are subject to change. Conclusion: The increase in metabolic/non-communicable diseases, increased consumer awareness of these diseases and their prevention, as well as developments in organic agriculture and functional food production require changes in economic research and calculations, also related to functional foods. Keywords: potato, market, marketability, organic agriculture, functional food","PeriodicalId":12623,"journal":{"name":"Functional Foods in Health and Disease","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43126812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}