用辣木籽提取物减轻健康个体的身体不适:一项随机、双盲、安慰剂对照、平行组试验

IF 1.3 Q4 FOOD SCIENCE & TECHNOLOGY
Aya Abe, Mahendra P. Kapoor, So Morishima, Derek Timm, Atsushi Nakajima, Makoto Ozeki, Norio Sato
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引用次数: 1

摘要

背景:辣木因其丰富的营养成分和多种生物活性成分而受到广泛认可。辣木富含各种生物活性化合物,如黄酮类化合物和生物碱,存在于包括叶子、茎和根在内的所有植物部位,其种子中尤其富含糖甙。辣木素的抗氧化活性已经在许多细胞和动物实验中得到证实。目的:研究富含糖合成素的辣木籽提取物(MSE)对健康人群疲劳相关身体不适和睡眠质量的影响,并以此作为生活质量的指标。方法:进行了一项随机、双盲、安慰剂对照、平行组研究,连续四周每天给健康成年男性和女性服用含有12毫克糖促生成素或安慰剂的MSE。生活质量(QOL)问卷的疲劳,身体不适,睡眠和动机使用视觉模拟量表(VAS)在研究开始时和随后的每个星期结束时进行评估,直到第4周。通过主观评价和氧化应激指标评估对生活质量的影响。结果:结果证实了MSE摄入对减轻肩颈僵硬痛、关节痛和肌肉痛的疗效。在氧化应激指标上,氧化应激水平较高的受试者表现出显著的影响。在服用MSE的女性参与者中,身体不适、疲劳减少和睡眠质量也得到了更大的改善。结论:MSE具有降低疲劳引起的身体不适、提高整体生活质量和改善睡眠质量的潜力。(UMIN000049070)关键词:辣木属;moringin;glucomoringin;身体不适;睡眠质量;疲劳;疼痛
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alleviating the physical discomfort in healthy individuals with Moringa seed extract: a randomized, double-blind, placebo-controlled, parallel-group trial
Background: Moringa oleifera is well recognized for its rich nutritional content and diverse bioactive compounds. Moringa, abundant in various bioactive compounds such as flavonoids and alkaloids present across all plant parts including leaves, stems, and roots, is especially rich in glucomoringin within its seeds. The antioxidant activity of moringin has already been verified in numerous cellular and animal experiments.Objective: The study investigates the effects of Moringa seed extract (MSE), abundant in glucomoringin, on fatigue-related physical discomfort and sleep quality, as indicators of quality of life (QOL) in healthy individuals.Methods: A randomized, double-blind, placebo-controlled, parallel-group study was conducted, administering MSE containing 12 mg of glucomoringin or placebo to healthy adult males and females daily for four consecutive weeks. Quality of life (QOL) questionnaire on fatigue, physical discomfort, sleep, and motivation was evaluated using a visual analog scale (VAS) at the start of the study and the end of each subsequent week until week 4. The impact on QOL was assessed through subjective evaluations and oxidative stress markers.Results: As a result, the efficacy of MSE intake in reducing stiff shoulder/neck pain, joint pain, and muscle pain was confirmed. Based on the oxidative stress markers, significant effects were observed among the participants with relatively high oxidative stress. A greater improvement in physical discomfort, reduced fatigue, and enhanced sleep quality were also noticed among female participants with MSE consumption. Conclusion: MSE consumption has showed potential in lowering physical discomfort brought on by exhaustion, promoting overall QOL, and improving sleep quality. (UMIN000049070)Keywords:moringa; moringin; glucomoringin; physical discomfort; sleep quality; fatigue; pain
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来源期刊
Functional Foods in Health and Disease
Functional Foods in Health and Disease FOOD SCIENCE & TECHNOLOGY-
CiteScore
2.20
自引率
20.00%
发文量
47
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