General hospital psychiatry最新文献

{"title":"Transforming primary care with transdiagnostic approaches: The future of mental health treatment through technology","authors":"Dwi Sri Rahayu , Erfan Ramadhani , Nila Zaimatus Septiana , Palasara Brahmani Laras , Rosalia Dewi Nawantara , Laelatul Arofah","doi":"10.1016/j.genhosppsych.2025.02.007","DOIUrl":"10.1016/j.genhosppsych.2025.02.007","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 129-130"},"PeriodicalIF":4.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing mental health outcomes in COPD patients: The global potential of telehealth interventions for anxiety and depression management","authors":"Nila Zaimatus Septiana , Binti Isrofin , Rosalia Dewi Nawantara","doi":"10.1016/j.genhosppsych.2025.02.003","DOIUrl":"10.1016/j.genhosppsych.2025.02.003","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 24-25"},"PeriodicalIF":4.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of antidepressant and antipsychotic use in the occurence of torsades de pointes arrhythmia: a case-control study","authors":"Samuel Cyr ,&nbsp;Lydia Abdelaziz ,&nbsp;Anthony Minichiello ,&nbsp;Maxime Bouvier ,&nbsp;Orielle Djona ,&nbsp;Céline Fiset ,&nbsp;Rafik Tadros ,&nbsp;Sylvie Levesque ,&nbsp;Charline Daval ,&nbsp;Viviane Lavigne ,&nbsp;Paul Khairy ,&nbsp;Stanley Nattel ,&nbsp;Judith Brouillette","doi":"10.1016/j.genhosppsych.2025.02.002","DOIUrl":"10.1016/j.genhosppsych.2025.02.002","url":null,"abstract":"<div><h3>Objectives and methods</h3><div>Psychotropic drugs may prolong the corrected QT interval (QTc), which has been associated with torsades de pointes (TdP). Our aim is to measure the relative impact of psychotropic drug use on TdP. A case-control study was conducted on 110 cases of confirmed TdP, and 330 matched controls. Hierarchical regression was performed by first including pre-identified risk factors (including demographic, medical conditions, and drugs such as antiarrhythmics) and then psychotropic drugs (antidepressants and antipsychotics). Population attributable risks (PAR) were calculated.</div></div><div><h3>Results</h3><div>At the time of admission, TdP was the primary, secondary, or complication diagnosis in 32.7 %, 30.9 %, and 36.4 % of cases, respectively. There were more patients with TdP who died during hospitalization compared to controls (7.3 % vs. 2.7 %, <em>p</em> &lt; 0.05), but TdP was the cause of death in only two (1.8 %) of them. In our final regression model, age, hepatic and/or renal failure and antidepressant/antipsychotic drug monotherapy were not associated with TdP. On the other hand, the use of other QTc-prolonging drugs, female sex, left ventricular dysfunction, acute myocardial infarction, hypokalemia, and use of ≥ 2 antidepressants were all significantly associated with TdP, with PAR of 55.3 %, 41.8 %, 26.2 %, 13.0 %, 11.7 %, and 6.3 % respectively.</div></div><div><h3>Conclusions</h3><div>In analyses adjusting for concomitant conditions/drugs, antidepressant or antipsychotic monotherapy was not associated with TdP while the use of ≥ 2 antidepressants was. However in terms of PAR, the use of other QTc-prolonging drug, including antiarrhythmics, sex, and left ventricular dysfunction carried a higher burden than the use of ≥2 antidepressants. These findings may inform and assist in balancing the risks and benefits of psychotropic drugs.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"94 ","pages":"Pages 16-23"},"PeriodicalIF":4.1,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143445396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming mental health: The impact of sensory substitution technologies on suicide ideation in hearing-impaired individuals","authors":"Nila Zaimatus Septiana ,&nbsp;Luthfi Atmasari ,&nbsp;Dwi Sri Rahayu ,&nbsp;Laelatul Arofah ,&nbsp;Rosalia Dewi Nawantara","doi":"10.1016/j.genhosppsych.2025.02.005","DOIUrl":"10.1016/j.genhosppsych.2025.02.005","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 127-128"},"PeriodicalIF":4.1,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of randomized controlled trials in a general practice setting aiming to reduce excess all-cause and enhance cardiovascular health in patients with severe mental illness","authors":"Kristina Langkilde ,&nbsp;Maria Haahr Nielsen ,&nbsp;Sofie Damgaard,&nbsp;Anne Møller,&nbsp;Maarten Pieter Rozing","doi":"10.1016/j.genhosppsych.2025.01.013","DOIUrl":"10.1016/j.genhosppsych.2025.01.013","url":null,"abstract":"<div><h3>Objective</h3><div>People with severe mental illness (SMI) have a reduced life expectancy, primarily due to chronic somatic diseases like cardiovascular disorders. Integrated care in general practice addressing mental and physical health may reduce excess mortality in this population. This review assessed the effectiveness of collaborative care, general integrated care, and physical health interventions in reducing overall mortality in patients with SMI. Secondary outcomes included disease-specific mortality, cardiovascular health indicators, and health-related quality of life.</div></div><div><h3>Methods</h3><div>We searched PubMed, PsycINFO, Cochrane Library, and Embase for randomized controlled trials published before April 24, 2024. Eligible studies focused on integrated care interventions targeting somatic health in patients with SMI. Two reviewers independently conducted data extraction and risk of bias assessment. The study was registered with PROSPERO (CRD42022328464).</div></div><div><h3>Results</h3><div>Of 2904 identified publications, 17 were included (covering 13 studies). Seven studies reported mortality data, with one showing reduced mortality in patients with major depressive disorder receiving collaborative care. No studies examined disease-specific mortality. Nine studies assessed cardiovascular outcomes, with three reporting reduced cardiovascular risk in collaborative care interventions simultaneously targeting depression and cardiovascular factors. Seven studies reported on quality of life, with three finding improvements. Study quality was rated moderate to high.</div></div><div><h3>Conclusion</h3><div>We found low-certainty evidence that collaborative care reduces mortality in depression. There was moderate evidence that collaborative care models, simultaneously addressing mental and cardiovascular health could potentially improve cardiovascular health in depression. The limited number of studies and their focus on depression limit the generalizability of these findings to other SMIs.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 131-143"},"PeriodicalIF":4.1,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health in the first year after ICU-treated sepsis: Analysis of administrative diagnoses in German health claims data","authors":"S. Sell ,&nbsp;C. Fleischmann-Struzek ,&nbsp;M. Spoden ,&nbsp;J. Rosendahl","doi":"10.1016/j.genhosppsych.2025.02.001","DOIUrl":"10.1016/j.genhosppsych.2025.02.001","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to quantify the (co-)occurrence of and risk factors for mental health impairments (MHI) in a cohort of sepsis survivors within 12 months after ICU stay in Germany.</div></div><div><h3>Method</h3><div>Population-based cohort study using nationwide de-identified health claims data of the German AOK health insurance. Patients with sepsis hospitalization and ICU treatment were identified by ICD-10 and procedural codes. Among 12-months survivors, we assessed new and prevalent MHI by ICD-10 diagnoses in the outpatient and inpatient health sector. Risk factors for MHI were assessed by multiple logistic regression analyses.</div></div><div><h3>Results</h3><div>Of 21,980 sepsis survivors, 54.8 % were diagnosed with any MHI in the 12 months post-discharge. 25.4 % of patients without pre-existing MHI had a new MHI diagnosis. Co-occurrence of MHI was common. Pre-existing depression, anxiety disorder, PTSD, substance use disorder and sleep disorder significantly increased the odds for a diagnosis of any MHI post-sepsis between six- and nine-fold, while treatment-related factors had no influence.</div></div><div><h3>Conclusions</h3><div>MHI is common among sepsis survivors, particularly in those affected by any pre-existing psychological diagnoses. Early assessment of pre-existing psychopathology might help to identify patients at risk for prevention or treatment interventions.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 109-115"},"PeriodicalIF":4.1,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The reliability and validity of the Chinese version of premenstrual dysphoric disorder questionnaire for DSM-5","authors":"Shanyi Huang ,&nbsp;Qiao Zhang ,&nbsp;Leire Aperribai ,&nbsp;Itziar Alonso-Arbiol ,&nbsp;Nekane Balluerka ,&nbsp;Ying Chen ,&nbsp;Yuecheng Wang ,&nbsp;Yuqun Zhang","doi":"10.1016/j.genhosppsych.2025.01.021","DOIUrl":"10.1016/j.genhosppsych.2025.01.021","url":null,"abstract":"<div><h3>Objective</h3><div>Premenstrual dysphoric disorder (PMDD) seriously affects women's work and life, and early screening and diagnosis of PMDD can improve the quality of life of potential PMDD patients. The Premenstrual Dysphoric Disorder Questionnaire for DSM-5 (CTDP-DSM-5) is a validated screening tool for PMDD based on the DSM-5. This study intends to conduct reliability testing and validity evaluation of the scale after translation and revision in Chinese women.</div></div><div><h3>Methods</h3><div>669 Chinese female college students were evaluated by a set of questionnaires including the Chinese version of CTDP-DSM-5 (CTDP-C), Patient Health Questionnaire-9 (PHQ-9), General Anxiety Disorder-7 (GAD-7) and Premenstrual Symptoms Screening Tool (PSST).</div></div><div><h3>Results</h3><div>CTDP-C is a bi-dimensional screening instrument with 25 items. The factor structure of the CTDP-C fits well to the factor model of the original Spanish version (CFI = 0.957; TLI = 0.953; RMSEA = 0.036; <em>χ</em>^<em>2</em> = 5983.585, <em>df</em> = 300, <em>p</em> &lt; 0.0001). The McDonald's omega reliability index obtained in this study was good (0.8) for both dimensions. In terms of convergent validity, the CTDP-C is significantly positively correlated with PSST (<em>r</em> = 0.533, <em>p</em> &lt; 0.01). Furthermore, the instrument correlates positively with depression and anxiety. Finally, the CTDP-C scores can sensitively differentiate depressed from non-depressed patients (<em>Cohen's d</em> = 0.72). Similarly, sensitively differentiated anxious from non-anxious patients (<em>Cohen's d</em> = 0.80).</div></div><div><h3>Conclusions</h3><div>CTDP-C has good validity and reliability and it is an effective screening tool to identify Chinese patients with PMDD among college students, providing a basis for early detection, early diagnosis and early treatment of PMDD.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 122-126"},"PeriodicalIF":4.1,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143395435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol use disorder and initiation of oral anticoagulant therapy in patients with atrial fibrillation: A nationwide cohort study","authors":"Miika Vanhanen ,&nbsp;Jussi Jaakkola ,&nbsp;Juhani K.E. Airaksinen ,&nbsp;Olli Halminen ,&nbsp;Jukka Putaala ,&nbsp;Pirjo Mustonen ,&nbsp;Jari Haukka ,&nbsp;Juha Hartikainen ,&nbsp;Alex Luojus ,&nbsp;Mikko Niemi ,&nbsp;Miika Linna ,&nbsp;Mika Lehto ,&nbsp;Konsta Teppo","doi":"10.1016/j.genhosppsych.2025.01.017","DOIUrl":"10.1016/j.genhosppsych.2025.01.017","url":null,"abstract":"<div><h3>Objective</h3><div>Patients with alcohol use disorders (AUD) often receive inferior care for somatic comorbidities. Our objective was to explore whether AUDs influence oral anticoagulant (OAC) initiation for stroke prevention among atrial fibrillation (AF) patients, using a nationwide dataset to assess treatment disparities.</div></div><div><h3>Methods</h3><div>The Finnish AntiCoagulation in Atrial Fibrillation registry includes data on all 229,565 patients diagnosed with incident AF in Finland during 2007–2018, identified from national registries covering all levels of care. The main outcome was OAC initiation compared between patients with and without AUD.</div></div><div><h3>Results</h3><div>The patients' mean age was 72.7 years, 50 % were female, 85.0 % were eligible for OAC therapy (CHA₂DS₂-VA score ≥ 1), and 4.7 % had AUD. OAC therapy was initiated in a smaller proportion of patients with AUD compared to those without (52.5 % vs. 71.4 %, <em>p</em> &lt; 0.001). This disparity remained significant even after adjusting for comorbidities, socioeconomic status, and laboratory values influencing OAC initiation (adjusted hazard ratio [HR] 0.68; 95 % confidence interval [0.66–0.71]). The absolute difference in OAC initiation between groups stayed consistent at approximately 20 % throughout the study period. Interaction analyses indicated that the association between AUD and lower OAC initiation was stronger in patients with lower income, lower educational attainment, and lower thrombocyte levels, but there was no significant interaction with sex, bleeding history, or hemoglobin levels.</div></div><div><h3>Conclusions</h3><div>AUDs are associated with a significantly lower rate of OAC initiation even after accounting for comorbidities that influence OAC initiation.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 116-121"},"PeriodicalIF":4.1,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies to safeguard psychiatric units in general hospitals: Overcoming closure risks for community support","authors":"Michitaka Funayama ,&nbsp;Fumi Maruyama ,&nbsp;Shigeru Nohara ,&nbsp;Naoko Satake ,&nbsp;Shigeki Sato ,&nbsp;Hiraki Koishikawa ,&nbsp;Ken Wada ,&nbsp;Yusuke Hasegawa ,&nbsp;On Kato ,&nbsp;Takaki Akahane ,&nbsp;Hisashi Wada ,&nbsp;Naohisa Tsujino ,&nbsp;Masayuki Noguchi ,&nbsp;Tomoji Takata ,&nbsp;Katsuji Nishimura","doi":"10.1016/j.genhosppsych.2025.01.014","DOIUrl":"10.1016/j.genhosppsych.2025.01.014","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 100-102"},"PeriodicalIF":4.1,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the efficacy of information technology-based CBT for older adults: Key considerations for future research","authors":"Wikan Galuh Widyarto ,&nbsp;Mufti Rasyid ,&nbsp;Muslihati ,&nbsp;IM. Hambali ,&nbsp;Adi Atmoko ,&nbsp;Dzinnun Hadi ,&nbsp;Muhammad Sholihuddin Zuhdi","doi":"10.1016/j.genhosppsych.2025.01.019","DOIUrl":"10.1016/j.genhosppsych.2025.01.019","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 103-104"},"PeriodicalIF":4.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143104314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}