General hospital psychiatry最新文献

{"title":"Expert and patient cognitive interviews in the development of a novel alcohol insight scale for use in hepatology and liver transplantation.","authors":"Gerald Scott Winder, Victoria Gill, Shivali Patel, Haila Asefa, Jessica L Mellinger","doi":"10.1016/j.genhosppsych.2024.09.010","DOIUrl":"10.1016/j.genhosppsych.2024.09.010","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":"256-258"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between depressive symptoms and participation in influenza vaccination and health checkups: Findings from the Korea National Health and Nutrition Examination Survey","authors":"Seong-Uk Baek ,&nbsp;Jin-Ha Yoon","doi":"10.1016/j.genhosppsych.2024.11.006","DOIUrl":"10.1016/j.genhosppsych.2024.11.006","url":null,"abstract":"<div><h3>Objective</h3><div>Promoting preventive healthcare service utilization is essential for disease prevention. This study explored the association between depressive symptoms and participation in influenza vaccinations and health checkups.</div></div><div><h3>Methods</h3><div>This cross-sectional study included a nationwide sample consisting of 26,692 Korean adults. Depressive symptoms were assessed using the Patient Health Questionnaire–9 and categorized as none, mild, and moderate-to-severe. Participation in influenza vaccination during the past year and routine health checkups during the past two years were assessed. Logistic regression analysis was used to determine the association between depressive symptoms and participation in influenza vaccination and health checkups, with odds ratios (ORs) and 95 % confidence intervals (CIs).</div></div><div><h3>Results</h3><div>The prevalence of non-, mild, and moderate-to-severe depressive symptoms was 80.7 %, 14.1 %, and 5.3 %, respectively. A total of 38.5 % and 66.9 % of the individuals participated in influenza vaccination and health checkups, respectively. In the adjusted model, the ORs (95 % CIs) of the association between depressive symptoms and vaccination uptake were 0.93 (0.84–1.02) for mild and 0.78 (0.67–0.90) for moderate-to-severe depressive symptoms, compared with those for non-depressive symptoms. Additionally, the adjusted ORs (95 % CIs) of the association between depressive symptoms and health checkup participation were 0.87 (0.79–0.96) for mild and 0.76 (0.65–0.87) for moderate-to-severe depressive symptoms, compared with those for non-depressive symptoms.</div></div><div><h3>Conclusion</h3><div>Our findings suggest that depressive symptoms are associated with the underuse of preventive healthcare services. This study underscores the need for targeted policy interventions to increase preventive healthcare utilization among individuals with depressive symptoms.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 180-185"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxidative stress and inflammatory factors mediate the association between dietary antioxidant intake and depressive symptoms in middle and old-aged individuals: A cross-sectional study from NHANES","authors":"Fangbo Lin ,&nbsp;Yanyao Deng ,&nbsp;Jie Li ,&nbsp;Chao Liu ,&nbsp;Le Xiao","doi":"10.1016/j.genhosppsych.2024.10.016","DOIUrl":"10.1016/j.genhosppsych.2024.10.016","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between dietary antioxidant intake and depression remains controversial. This study aimed to explore the intermediary role of oxidative stress and inflammatory markers in linking dietary antioxidant intake to depression among middle-aged and older adults.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study from the 2003–2014 National Health and Nutrition Examination Survey (NHANES), depressive symptoms were identified using a score of 10 or above on the Patient Health Questionnaire-9 (PHQ-9). Dietary antioxidant intake was measured via the Composite Dietary Antioxidant Index (CDAI). We utilized multivariable logistic regression to assess the link between CDAI and depression risk, followed by mediation analysis to explore the potential mediating effects of oxidative stress and inflammatory markers.</div></div><div><h3>Results</h3><div>In the multivariate analysis, a robust inverse relationship was noted between the Composite Dietary Antioxidant Index (CDAI) and depression risk, with participants in the upper CDAI tertile demonstrating a 36 % reduced risk compared to those in the lower tertile (OR: 0.64, 95 % CI: 0.53–0.79; <em>P</em> &lt; 0.001). The relationship was nearly linear, as indicated by restricted cubic splines. Furthermore, higher CDAI scores were linked to lower depression scores (β = −0.03, 95 % CI: −0.05 to −0.01; <em>P</em> &lt; 0.001). Mediation analysis indicated that GGT, albumin, and the systemic immune-inflammation index (SII) accounted for 4.6 %, 6.3 %, and 6.1 % of the CDAI-depression association, respectively, with a total mediated effect of 11.4 % (all <em>P</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The CDAI exhibits a significant negative association with depression, potentially mediated by oxidative stress and inflammation among middle-aged and older adults.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 160-166"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding identification of housing instability and referral to homeless programing: VA suicide risk screening and evaluation as a critical intercept.","authors":"Ryan Holliday, Evan Polzer, Lindsey L Monteith, Bridget B Matarazzo, Jack Tsai","doi":"10.1016/j.genhosppsych.2024.07.007","DOIUrl":"10.1016/j.genhosppsych.2024.07.007","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":"225-226"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141787781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicidal ideation among U.S. adults aged 20 and older with and without tinnitus: A retrospective study.","authors":"Ying Cui, Tong Wu, Wen Zhang","doi":"10.1016/j.genhosppsych.2024.09.009","DOIUrl":"10.1016/j.genhosppsych.2024.09.009","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":"253-255"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results from a benzodiazepine-minimizing protocol for inpatient management of alcohol withdrawal","authors":"Jennifer Gaston ,&nbsp;Emily J. Cox ,&nbsp;Hsin-Fang Li ,&nbsp;Caitlin Klamper ,&nbsp;John F. Wurzel III","doi":"10.1016/j.genhosppsych.2024.11.010","DOIUrl":"10.1016/j.genhosppsych.2024.11.010","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 191-193"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of tele-based interventions for depression and anxiety symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD): A systematic review and meta-analysis","authors":"Yu-Fei Qiu ,&nbsp;Ji-Sheng Hu ,&nbsp;Man Wu ,&nbsp;Jia-Li Liu ,&nbsp;Chao-Yang Li ,&nbsp;Yi-Qing Yu ,&nbsp;Li-Juan Zeng ,&nbsp;Fen Yang ,&nbsp;Lan Zheng","doi":"10.1016/j.genhosppsych.2024.10.014","DOIUrl":"10.1016/j.genhosppsych.2024.10.014","url":null,"abstract":"<div><h3>Background</h3><div>Depression and anxiety are common psychiatric symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD). While face-to-face psychotherapy is a common option, tele-based interventions provide a more accessible alternative. However, a comprehensive synthesis of evidence from clinical trials for COPD patients has yet to be conducted.</div></div><div><h3>Objective</h3><div>This study aims to evaluate the effects of tele-based interventions in reducing depressive and anxiety symptoms in patients with COPD.</div></div><div><h3>Methods</h3><div>A systematic search of PubMed, EMBASE, the Cochrane Library, Web of Science, PsycINFO, and MEDLINE databases was conducted from inception to May 5, 2024. Eligible studies included Randomized Controlled Trials (RCTs) of people with COPD patients receiving tele-based interventions reporting on the outcomes of depression or anxiety. Data extraction and quality assessment were performed independently by two researchers. The quality of the included studies was assessed using the Cochrane risk-of-bias tool. Meta-analysis was performed using RevMan (version 5.4) and Stata (version 18.0) software.</div></div><div><h3>Results</h3><div>Following the search, 9 RCTs with a total of 2064 patients with COPD were included. The meta-analysis revealed that tele-based interventions reduced depressive symptoms in patients with COPD (Standardized Mean Difference [SMD] = −0.15, 95 % CI −0.24 to −0.06; <em>P</em> = 0.001). The subgroup analysis indicated that the PHQ-9 (SMD = −0.24, 95 % CI −0.37 to −0.10; <em>P =</em> 0.001) was better at detecting changes in depressive symptoms compared to other scales; the first 3 months of intervention (SMD = −0.36, 95 % CI −0.52 to −0.19; <em>P</em> <em>&lt;</em> 0.001) was the most pronounced improvement; and telehealth interventions were more effective (SMD = −0.30, 95 % CI −0.46 to −0.15; <em>P &lt;</em> 0.001) than telemonitoring interventions. Tele-based interventions also reduced anxiety symptoms in patients with COPD (SMD = −0.12, 95 % CI −0.22 to −0.02; <em>P</em> = 0.02).</div></div><div><h3>Conclusions</h3><div>The evidence supports the efficacy of tele-based interventions in alleviating depression and anxiety symptoms in COPD patients. However, further large-scale and rigorously designed studies are warranted to strengthen the evidence.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 143-150"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of N-acetylcysteine for patients with depression: An updated systematic review and meta-analysis","authors":"Tzu-Rong Peng ,&nbsp;Hung-Hong Lin ,&nbsp;Tzu-Ling Tseng ,&nbsp;Yun-Hui Huang ,&nbsp;Pei-Yun Tsai ,&nbsp;Chia-Yu Lin ,&nbsp;Ming-Chia Lee ,&nbsp;Shih-Ming Chen","doi":"10.1016/j.genhosppsych.2024.10.018","DOIUrl":"10.1016/j.genhosppsych.2024.10.018","url":null,"abstract":"<div><h3>Background</h3><div>Results on whether <em>N</em>-acetylcysteine (NAC) ameliorates depression in patients with psychiatric problems, such as bipolar disorder and major depressive disorder, remain inconsistent, and several new studies have recently been published. Thus, we conducted an uptodated meta-analysis to evaluate the efficacy of NAC against depression.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis included randomized controlled trials where NAC was used to treat depression. The present study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Embase (Ovid), and Cochrane were searched for relevant articles. A random-effects model was used to evaluate the primary outcome—efficacy of NAC in ameliorating depression.</div></div><div><h3>Results</h3><div>This review included 12 studies (904 patients with depression). The daily dose of NAC in the included studies ranged from 1000 to 3000 mg. The duration of NAC treatment ranged from 8 to 24 weeks. A significant difference was noted between NAC and placebo in terms of the change in mean depression score from baseline to treatment conclusion (standardized mean difference = −0.24; 95 % confidence interval (CI) = −0.44 to −0.05; <em>I</em>² = 45 %; <em>P</em> = .02).</div></div><div><h3>Conclusion</h3><div>Our findings indicate that adjunctive NAC can ameliorate depressive symptoms in patients with psychiatric problems, particularly bipolar disorder. However, large-scale clinical trials were needed to substantiate our results due to the wide CI value.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 151-159"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ACT with CF: A randomized trial of acceptance and commitment therapy vs supportive psychotherapy for adults with cystic fibrosis","authors":"C. Virginia O'Hayer ,&nbsp;Patrick J. Smith ,&nbsp;Christopher F. Drescher ,&nbsp;Heather Bruschwein ,&nbsp;Chelsi N. Nurse ,&nbsp;Hallie M. Kushner ,&nbsp;Krista Ingle ,&nbsp;Michael J. Stephen ,&nbsp;Jeffrey B. Hoag","doi":"10.1016/j.genhosppsych.2024.11.011","DOIUrl":"10.1016/j.genhosppsych.2024.11.011","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;Psychological distress, including anxiety and depression, is common among adults with CF, associating with poor quality of life, lung function, and healthcare utilization. This 3-year, multi-site, telehealth-delivered randomized trial sought to determine whether Acceptance and Commitment Therapy (ACT with CF) is superior to supportive psychotherapy (SP), in improving psychological functioning for adults with CF.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;One hundred twenty-four adults with CF and elevated anxiety and/or depressive symptoms were recruited coincident with the first COVID lockdown, from Thomas Jefferson University Hospitals, University of Virginia, Augusta University, Duke University Medical Center, and social media. Participants were randomized to 6 weeks of either ACT with CF or SP, delivered via Zoom. They completed measures of psychological functioning: depression (BDI-II), anxiety (BAI), cognitive fusion (CFQ-13), acceptance and committed action (AAQ-II); and barriers to adherence at baseline, post-treatment, and at 3-months follow-up. Biobehavioral outcomes, including CF severity and treatment burden, were gathered using EMR data.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Participants were young adults (mean age 25 years [SD = 12]), female (75 %), on CFTR modulators (67 %), psychotropic medication(s) (60 %), with previous psychotherapy engagement (72 %). Treatment effects were evaluated using analysis of covariance, controlling for baseline levels of respective outcomes, age, biological sex, and FEV&lt;sub&gt;1&lt;/sub&gt;. ACT demonstrated greater improvements in psychological functioning at 6-weeks (mean score = 57.3 [51.6, 63.0]) relative to SP (mean score = 67.8 [62.2, 73.5], Cohen's d = 0.59, &lt;em&gt;P&lt;/em&gt; = .017), with largest improvements in cognitive fusion (CFQ-13) and acceptance and committed action (AAQ-II). Treatment improvements in psychological functioning persisted at 3-months (ACT: 59.7 (53.5, 65.9) vs. SP: 69.0 [62.6, 75.4], Cohen's d = 0.40, &lt;em&gt;P&lt;/em&gt; = .041), with ACT demonstrating continued improvements in the CFQ-13 and AAQ-II. Negative affect scores were not consistently improved on our mean-rank composite outcome variable (Cohen's d = 0.22, &lt;em&gt;P&lt;/em&gt; = .170), despite post hoc reductions in BDI-II scores (ACT: −7.4 [−9.4, −5.4] vs. SP: −4.5 [−6.4, −2.6], &lt;em&gt;P&lt;/em&gt; = .040). Improvements in psychological flexibility (CFQ-13 and AAQ-II) were also robustly associated with reductions in negative affect (B = −0.45, &lt;em&gt;P&lt;/em&gt; &lt; .001). Individuals in ACT with greater baseline barriers to medication adherence reported greater reductions in barriers after treatment (&lt;em&gt;P&lt;/em&gt; = .026). Individuals with lower baseline FEV&lt;sub&gt;1&lt;/sub&gt;/FVC ratios (e.g. ≤ 65 %) demonstrating greater improvements in ACT compared with SP (ACT: 7.3 [1.7, 12.8] vs. SP: 1.3 [−3.2, 5.8], &lt;em&gt;P&lt;/em&gt; = .036 for interaction).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;ACT with CF was superior to SP in improving psychological functioning am","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 212-222"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142759310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of a French hospital administrative database to measure self-harm in epidemiology studies.","authors":"C Quantin, J Cottenet, A S Mariet, S Maach, J C Chauvet, F Jollant","doi":"10.1016/j.genhosppsych.2024.07.008","DOIUrl":"10.1016/j.genhosppsych.2024.07.008","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":"227-229"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}