{"title":"Telepsychiatry consults in an academic health organization","authors":"Julie Hwang , Xiaoming Zeng , Nathaniel A. Sowa","doi":"10.1016/j.genhosppsych.2025.07.015","DOIUrl":"10.1016/j.genhosppsych.2025.07.015","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 195-196"},"PeriodicalIF":4.1,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shannon L. Walker , Rebekah J. Walker , Joni S. Williams , Aprill Z. Dawson , Anna Palatnik , Leonard E. Egede
{"title":"Association between social determinants of health and postpartum quality of life in Black women","authors":"Shannon L. Walker , Rebekah J. Walker , Joni S. Williams , Aprill Z. Dawson , Anna Palatnik , Leonard E. Egede","doi":"10.1016/j.genhosppsych.2025.07.016","DOIUrl":"10.1016/j.genhosppsych.2025.07.016","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 197-198"},"PeriodicalIF":4.1,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cui Ma , De-Feng Zhao , Lu Zhai , Rong-Rui Huo , Yu-Hua Liu
{"title":"Role of depressive symptoms in accelerating cardiovascular diseases progression in cardiovascular-kidney-metabolic syndrome stages 0–3: A nationwide prospective cohort study","authors":"Cui Ma , De-Feng Zhao , Lu Zhai , Rong-Rui Huo , Yu-Hua Liu","doi":"10.1016/j.genhosppsych.2025.07.013","DOIUrl":"10.1016/j.genhosppsych.2025.07.013","url":null,"abstract":"<div><h3>Objective</h3><div>To examine the association of depressive symptoms with cardiovascular disease (CVD) risk in middle-aged and older adults with Cardiovascular-Kidney-Metabolic (CKM) syndrome stages 0–3 and to assess whether this association varies by CKM syndrome stages. Also, interactions of depressive symptoms with CKM syndrome stages in relation to CVD risk were evaluated.</div></div><div><h3>Methods</h3><div>This study analyzed data from the China Health and Retirement Longitudinal Study (CHARLS). Incident CVD events were identified based on self-reported physician-diagnosed (Participants were asked whether they had ever been diagnosed with disease by a physician). Cox proportional hazards regression models were used to estimate the association between depressive symptoms and CVD risk with interaction analyses across CKM syndrome stages.</div></div><div><h3>Results</h3><div>Among 3440 participants, 1833 (53.3 %) were women. Over the 7-year follow-up, 696 (20.2 %) developed CVD. After full adjustment, elevated depressive symptoms were associated with a 27.0 % higher CVD risk (HR, 1.27; 95 % CI, 1.07–1.50). Of the 10 individual depressive symptoms, only restless sleep (HR, 1.23; 95 % CI, 1.04–1.44), loneliness (HR, 1.26; 95 % CI, 1.05–1.52), and bothered by little things (HR, 1.21; 95 % CI, 1.01–1.45) were significantly associated with incident CVD. Moreover, depressive symptoms and CKM syndrome stages exhibited both multiplicative and additive interactions. Notably, in CKM syndrome stage 3, depressive symptoms were associated with a 36.0 % higher CVD risk (HR, 1.36; 95 % CI, 1.09–1.70).</div></div><div><h3>Conclusions</h3><div>Elevated depressive symptoms are associated with increased CVD risk in middle-aged and older adults with CKM syndrome stages 0–3, with a synergistic effect observed as CKM syndrome progresses. Highlighting the integration of mental health assessments into CKM risk stratification may enhance early intervention strategies and reduce CVD burden.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 183-192"},"PeriodicalIF":4.1,"publicationDate":"2025-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor: Referral to chronic pain management and physiotherapy services in adults with severe mental illness: A matched cohort study","authors":"Amina Irfan","doi":"10.1016/j.genhosppsych.2025.07.011","DOIUrl":"10.1016/j.genhosppsych.2025.07.011","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 181-182"},"PeriodicalIF":4.1,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaclyn Boozalis , Jaclyn Perreault , Helen I. Turner , Wen-Chih Wu , Julia Browne , Lan Jiang , Mitchell Wice , James L. Rudolph , Jensy P. Stafford
{"title":"A retrospective study of deceased veterans with serious mental illness and heart failure: Analysis of palliative care and mental health collaboration on hospice utilization","authors":"Jaclyn Boozalis , Jaclyn Perreault , Helen I. Turner , Wen-Chih Wu , Julia Browne , Lan Jiang , Mitchell Wice , James L. Rudolph , Jensy P. Stafford","doi":"10.1016/j.genhosppsych.2025.07.009","DOIUrl":"10.1016/j.genhosppsych.2025.07.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Serious Mental Illness (SMI) adds complexity to end of life care including medical decision making. For complex patients, enrollment in team-based hospice care providescoordinated services and supports. This retrospective study evaluated if the combinations of mental health care or palliative care increased hospice enrollment in the last 6 months of life.</div></div><div><h3>Methods</h3><div>We identified deceased Veterans with diagnoses of heart failure (HF) and SMI. SMI was defined as schizophrenia spectrum or bipolar spectrum disorder. We categorized the SMI population into 4 groups: those with mental health and palliative care (<em>n</em> = 2973), only mental health (<em>n</em> = 4333), only palliative care (<em>n</em> = 892), or neither (<em>n</em> = 1171). The outcome of hospice use in the 6-months before death was measured with VA and Medicare records. Logistic regression compared the mental health and palliative care groups to the reference group and included adjustment for demographics and comorbidities.</div></div><div><h3>Results</h3><div>The cohort included 9369 Veterans with HF and SMI who died between 2011 and 2020. Relative to the reference group (23.9 % hospice), those with mental health engagement had lower odds of receiving hospice (adjusted Odds Ratio (aOR) = 0.74; 95 % confidence interval (CI) 0.62,0.87). Exposure to palliative care increased the adjusted odds of hospice in those with mental health services (aOR = 6.67, 95 % CI 5.61, 7.92) and with only palliative care (aOR = 5.96, 95 % CI 4.86, 7.32).</div></div><div><h3>Conclusion</h3><div>This study demonstrates a gap in hospice enrollment for people with SMI. Palliative care improves the gap. Increased collaboration between mental health and palliative providers and cross-training may improve the experience of people with SMI.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 151-155"},"PeriodicalIF":4.1,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astrid M. Widjaja , Sarah Edwards , Shauna P. Reinblatt , Lily Stavisky , Grace S. McIlmoyle , Amie F. Bettencourt
{"title":"Role of child psychiatry access programs in pediatric feeding and eating concerns","authors":"Astrid M. Widjaja , Sarah Edwards , Shauna P. Reinblatt , Lily Stavisky , Grace S. McIlmoyle , Amie F. Bettencourt","doi":"10.1016/j.genhosppsych.2025.07.004","DOIUrl":"10.1016/j.genhosppsych.2025.07.004","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 168-170"},"PeriodicalIF":4.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144652969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-stroke depression risk prediction models in stroke patients: A systematic review","authors":"Xiang Zeng, Xiao Juan Chen","doi":"10.1016/j.genhosppsych.2025.07.003","DOIUrl":"10.1016/j.genhosppsych.2025.07.003","url":null,"abstract":"<div><h3>Background</h3><div>Post-stroke depression (PSD) is a severe complication that significantly affects patients' prognosis. It is widely believed that risk prediction models can be employed to identify patients early and develop intervention measures. Although the number of PSD prediction models has gradually increased, the quality and applicability of these models remain unclear.</div></div><div><h3>Objective</h3><div>This study aims to systematically review the published research on risk prediction models for PSD.</div></div><div><h3>Methods</h3><div>A computer search was conducted in databases including CNKI, WanFang Data, VIP, CBM, PubMed, EMbase, Web of Science, CINAHL, and The Cochrane Library, collecting studies on PSD risk prediction models. The search time frame spanned from the establishment of these databases to March 1, 2025. Two researchers independently screened the literature, extracted data, and assessed the risk of bias for the included studies before performing a qualitative systematic review.</div></div><div><h3>Results</h3><div>A total of 12 studies were included, comprising 13 risk prediction models. The area under the curve (AUC) or C-index of these models ranged from 0.726 to 0.928. The risk of bias assessment indicated that all the included models were at high risk, with three models demonstrating poor applicability. The most commonly included predictors in the models were, in order: Barthel Index, NIHSS score, age, hypertension, and education level.</div></div><div><h3>Conclusion</h3><div>Overall, the predictive performance of PSD risk prediction models is promising. However, limitations remain that require further optimization, including issues related to data sources, study design, and data processing. Future research should prioritize the external validation of existing prediction models or the development of higher-quality models with enhanced applicability.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 132-139"},"PeriodicalIF":4.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ziyu Wang , Lu Lin , Shufang Zuo , Cui Ye , Xuan Huang , Yong Xu
{"title":"Prevalence of cognitive frailty among Chinese older adults: A systematic review and meta-analysis","authors":"Ziyu Wang , Lu Lin , Shufang Zuo , Cui Ye , Xuan Huang , Yong Xu","doi":"10.1016/j.genhosppsych.2025.07.008","DOIUrl":"10.1016/j.genhosppsych.2025.07.008","url":null,"abstract":"<div><h3>Background and purpose</h3><div>With China's aging population, the prevalence of cognitive frailty (CF) is increasing, posing significant risks such as reduced quality of life, higher hospitalization and mortality rates, cognitive impairment, and dementia. This study aimed to determine the prevalence of CF among Chinese older adults through a systematic review and meta-analysis to provide evidence that informs healthcare policy and practice.</div></div><div><h3>Methods</h3><div>A systematic search was conducted across eight databases: PubMed, Web of Science, Embase, the Cochrane Library, CNKI, WanFang, VIP, and SinoMed from their inception up to April 5, 2024. Observational studies (cross-sectional, cohort, or population-based longitudinal studies) were included. Two researchers independently reviewed the literature, extracted data, and assessed the quality of the studies. All statistical analyses were performed using Stata 14.2.</div></div><div><h3>Results</h3><div>A total of 79,059 records were screened, of which 93 studies involving 89,760 Chinese older adults met the inclusion criteria. The pooled CF prevalence was determined to be 21 % (95 % CI: 0.19, 0.23, <em>P</em> < 0.001). Notably, CF prevalence varied significantly across subgroups, depending on variables such as age, gender, education, marital status, living arrangements, presence of hypertension, presence of diabetes, BMI, history of falls, nutritional status, sleep condition, exercise, activities of daily living, polypharmacy, and presence of depressive symptoms (all <em>P</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>This study revealed a pooled CF prevalence of 21 % among Chinese older adults, with a concerning upward trend from 2012 to 2023. The CF prevalence was influenced by demographic, health, and lifestyle factors. These findings underscore the complexity of CF and highlight the need to identify key risk and protective factors, as well as to develop targeted interventions that address both health and lifestyle factors in this population.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 156-167"},"PeriodicalIF":4.1,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bijen Upadhyay , Sheila Abdolmanafi , Tanmay Bhatnagar , Mustafa Al Jnainati , Jana Al Jnainati , Partha Baral , Muhammad Faisal Shakir
{"title":"High-dose olanzapine versus clozapine for treatment-resistant schizophrenia: A systematic review and meta-analysis","authors":"Bijen Upadhyay , Sheila Abdolmanafi , Tanmay Bhatnagar , Mustafa Al Jnainati , Jana Al Jnainati , Partha Baral , Muhammad Faisal Shakir","doi":"10.1016/j.genhosppsych.2025.07.006","DOIUrl":"10.1016/j.genhosppsych.2025.07.006","url":null,"abstract":"<div><div>Treatment-resistant schizophrenia (TRS) affects approximately 30 % of schizophrenia patients and represents a significant clinical challenge. Although clozapine remains the gold standard treatment, it is underutilized due to hematological monitoring requirements, though recent FDA guidance has made such monitoring less restrictive. High-dose olanzapine has emerged as a potential alternative; however, comparative evidence has been mixed. We conducted a systematic review and meta-analysis following PRISMA guidelines. Four electronic databases were searched, from inception to February 2025. Studies that directly compared high-dose olanzapine (≥20 mg/day) with clozapine in treatment-resistant populations were included. The primary outcomes included changes in overall psychopathology as measured by PANSS total scores or BPRS total scores, along with positive and negative symptom subscales, positive and negative symptoms, and adverse events. Twelve studies met the inclusion criteria, which were included in the meta-analysis. Using random-effects models, clozapine demonstrated significant superiority for positive symptoms (MD = −1.30, 95 % CI [−2.52, −0.08]), whereas differences in overall psychopathology (MD = −2.50, 95 % CI [−6.53, 1.53]) and negative symptoms (MD = 0.21, 95 % CI [−1.96, 2.38]) were not significant. High heterogeneity was observed across the outcomes (I<sup>2</sup> = 61–98 %). In the pediatric population, clozapine showed clear superiority. Olanzapine demonstrated better general tolerability with lower discontinuation rates due to adverse events but Some studies showed significantly greater weight gain with high-dose olanzapine (≥20 mg/day) compared to clozapine (15.9 vs 3.5 lbs). Although clozapine remains the most effective option for TRS, particularly for positive symptoms, high-dose olanzapine represents a viable alternative with a different efficacy and risk profile. Treatment decisions should be individualized, considering specific symptom profiles, prior treatment responses, susceptibility to side effects, and patient preferences. Both medications require careful monitoring for metabolic side effects.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 140-150"},"PeriodicalIF":4.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144623778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}