General hospital psychiatry最新文献

{"title":"Prevalence of reversible visual impairments and their association with the psychiatric illness severity among inpatients with psychotic disorders.","authors":"Mathieu Fradet, Fannie Nadeau, Alexandre Suey, Mazen Choulakian, Sylvain Grignon","doi":"10.1016/j.genhosppsych.2024.11.005","DOIUrl":"https://doi.org/10.1016/j.genhosppsych.2024.11.005","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health effects of neurosurgery for drug-resistant epilepsy.","authors":"Irving Gabriel Calisaya-Madariaga, Lia Valentina Ubillús Peña","doi":"10.1016/j.genhosppsych.2024.11.002","DOIUrl":"https://doi.org/10.1016/j.genhosppsych.2024.11.002","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer screening among people with schizophrenia before and after the COVID-19 pandemic in Ontario, Canada: Retrospective cohort study.","authors":"Braden O'Neill, John Wang, Jessica Gronsbell, Debra Butt, Anthony Train, Angela Ortigoza, Bianca Seaton, Andrea Gershon, Karen Tu","doi":"10.1016/j.genhosppsych.2024.10.017","DOIUrl":"https://doi.org/10.1016/j.genhosppsych.2024.10.017","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxidative stress and inflammatory factors mediate the association between dietary antioxidant intake and depressive symptoms in middle and old-aged individuals: A cross-sectional study from NHANES","authors":"Fangbo Lin ,&nbsp;Yanyao Deng ,&nbsp;Jie Li ,&nbsp;Chao Liu ,&nbsp;Le Xiao","doi":"10.1016/j.genhosppsych.2024.10.016","DOIUrl":"10.1016/j.genhosppsych.2024.10.016","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between dietary antioxidant intake and depression remains controversial. This study aimed to explore the intermediary role of oxidative stress and inflammatory markers in linking dietary antioxidant intake to depression among middle-aged and older adults.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study from the 2003–2014 National Health and Nutrition Examination Survey (NHANES), depressive symptoms were identified using a score of 10 or above on the Patient Health Questionnaire-9 (PHQ-9). Dietary antioxidant intake was measured via the Composite Dietary Antioxidant Index (CDAI). We utilized multivariable logistic regression to assess the link between CDAI and depression risk, followed by mediation analysis to explore the potential mediating effects of oxidative stress and inflammatory markers.</div></div><div><h3>Results</h3><div>In the multivariate analysis, a robust inverse relationship was noted between the Composite Dietary Antioxidant Index (CDAI) and depression risk, with participants in the upper CDAI tertile demonstrating a 36 % reduced risk compared to those in the lower tertile (OR: 0.64, 95 % CI: 0.53–0.79; <em>P</em> &lt; 0.001). The relationship was nearly linear, as indicated by restricted cubic splines. Furthermore, higher CDAI scores were linked to lower depression scores (β = −0.03, 95 % CI: −0.05 to −0.01; <em>P</em> &lt; 0.001). Mediation analysis indicated that GGT, albumin, and the systemic immune-inflammation index (SII) accounted for 4.6 %, 6.3 %, and 6.1 % of the CDAI-depression association, respectively, with a total mediated effect of 11.4 % (all <em>P</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The CDAI exhibits a significant negative association with depression, potentially mediated by oxidative stress and inflammation among middle-aged and older adults.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 160-166"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of tele-based interventions for depression and anxiety symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD): A systematic review and meta-analysis","authors":"Yu-Fei Qiu ,&nbsp;Ji-Sheng Hu ,&nbsp;Man Wu ,&nbsp;Jia-Li Liu ,&nbsp;Chao-Yang Li ,&nbsp;Yi-Qing Yu ,&nbsp;Li-Juan Zeng ,&nbsp;Fen Yang ,&nbsp;Lan Zheng","doi":"10.1016/j.genhosppsych.2024.10.014","DOIUrl":"10.1016/j.genhosppsych.2024.10.014","url":null,"abstract":"<div><h3>Background</h3><div>Depression and anxiety are common psychiatric symptoms in patients with Chronic Obstructive Pulmonary Disease (COPD). While face-to-face psychotherapy is a common option, tele-based interventions provide a more accessible alternative. However, a comprehensive synthesis of evidence from clinical trials for COPD patients has yet to be conducted.</div></div><div><h3>Objective</h3><div>This study aims to evaluate the effects of tele-based interventions in reducing depressive and anxiety symptoms in patients with COPD.</div></div><div><h3>Methods</h3><div>A systematic search of PubMed, EMBASE, the Cochrane Library, Web of Science, PsycINFO, and MEDLINE databases was conducted from inception to May 5, 2024. Eligible studies included Randomized Controlled Trials (RCTs) of people with COPD patients receiving tele-based interventions reporting on the outcomes of depression or anxiety. Data extraction and quality assessment were performed independently by two researchers. The quality of the included studies was assessed using the Cochrane risk-of-bias tool. Meta-analysis was performed using RevMan (version 5.4) and Stata (version 18.0) software.</div></div><div><h3>Results</h3><div>Following the search, 9 RCTs with a total of 2064 patients with COPD were included. The meta-analysis revealed that tele-based interventions reduced depressive symptoms in patients with COPD (Standardized Mean Difference [SMD] = −0.15, 95 % CI −0.24 to −0.06; <em>P</em> = 0.001). The subgroup analysis indicated that the PHQ-9 (SMD = −0.24, 95 % CI −0.37 to −0.10; <em>P =</em> 0.001) was better at detecting changes in depressive symptoms compared to other scales; the first 3 months of intervention (SMD = −0.36, 95 % CI −0.52 to −0.19; <em>P</em> <em>&lt;</em> 0.001) was the most pronounced improvement; and telehealth interventions were more effective (SMD = −0.30, 95 % CI −0.46 to −0.15; <em>P &lt;</em> 0.001) than telemonitoring interventions. Tele-based interventions also reduced anxiety symptoms in patients with COPD (SMD = −0.12, 95 % CI −0.22 to −0.02; <em>P</em> = 0.02).</div></div><div><h3>Conclusions</h3><div>The evidence supports the efficacy of tele-based interventions in alleviating depression and anxiety symptoms in COPD patients. However, further large-scale and rigorously designed studies are warranted to strengthen the evidence.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 143-150"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of N-acetylcysteine for patients with depression: An updated systematic review and meta-analysis","authors":"Tzu-Rong Peng ,&nbsp;Hung-Hong Lin ,&nbsp;Tzu-Ling Tseng ,&nbsp;Yun-Hui Huang ,&nbsp;Pei-Yun Tsai ,&nbsp;Chia-Yu Lin ,&nbsp;Ming-Chia Lee ,&nbsp;Shih-Ming Chen","doi":"10.1016/j.genhosppsych.2024.10.018","DOIUrl":"10.1016/j.genhosppsych.2024.10.018","url":null,"abstract":"<div><h3>Background</h3><div>Results on whether <em>N</em>-acetylcysteine (NAC) ameliorates depression in patients with psychiatric problems, such as bipolar disorder and major depressive disorder, remain inconsistent, and several new studies have recently been published. Thus, we conducted an uptodated meta-analysis to evaluate the efficacy of NAC against depression.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis included randomized controlled trials where NAC was used to treat depression. The present study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Embase (Ovid), and Cochrane were searched for relevant articles. A random-effects model was used to evaluate the primary outcome—efficacy of NAC in ameliorating depression.</div></div><div><h3>Results</h3><div>This review included 12 studies (904 patients with depression). The daily dose of NAC in the included studies ranged from 1000 to 3000 mg. The duration of NAC treatment ranged from 8 to 24 weeks. A significant difference was noted between NAC and placebo in terms of the change in mean depression score from baseline to treatment conclusion (standardized mean difference = −0.24; 95 % confidence interval (CI) = −0.44 to −0.05; <em>I</em>² = 45 %; <em>P</em> = .02).</div></div><div><h3>Conclusion</h3><div>Our findings indicate that adjunctive NAC can ameliorate depressive symptoms in patients with psychiatric problems, particularly bipolar disorder. However, large-scale clinical trials were needed to substantiate our results due to the wide CI value.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 151-159"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review and meta-analysis of transdiagnostic interventions for common mental disorders in primary care","authors":"Marie Vogel ,&nbsp;Christopher Ebert ,&nbsp;Jochen Gensichen ,&nbsp;Hanna Applis ,&nbsp;Alkomiet Hasan ,&nbsp;Kirsten Lochbühler ,&nbsp;POKAL-Group","doi":"10.1016/j.genhosppsych.2024.11.003","DOIUrl":"10.1016/j.genhosppsych.2024.11.003","url":null,"abstract":"<div><h3>Objective</h3><div>In primary care, treating common mental disorders according to the ICD or DSM is challenging. A transdiagnostic approach may facilitate the management of mental health problems by treating across psychiatric diagnoses.</div><div>This meta-analysis aims to identify and compare transdiagnostic interventions delivered in primary care and to determine the effectiveness of these interventions, focusing on common mental disorders.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted by searching the databases Medline, Embase, Web of Science, and PsycINFO. Standardized mean differences (SMD) were calculated for the outcomes, and additional subgroup analyses were performed.</div></div><div><h3>Results</h3><div>From an initial set of 10,618 RCTs, 38 studies were included and retained for data extraction. Transdiagnostic interventions led to a significant reduction in symptoms of depression (SMD: −0.38) and anxiety (SMD: - 0.47). Treatment outcomes for somatoform disorders were not significant (SMD: - 0.22). About half of the interventions were provided by health professionals not specifically trained in psychotherapy; these interventions also proved to be effective (depression: SMD: −0.47; anxiety: −0.39).</div></div><div><h3>Conclusion</h3><div>This meta-analysis supports the use of transdiagnostic interventions for common mental disorders in primary care. Transdiagnostic interventions carried out by medical and health professionals not specifically trained in psychotherapy are feasible in PC, but emphasis should be placed on adequate training for them.</div><div>Trial registration: The protocol for this study is registered with PROSPERO: CRD42024459073, Date of registration: 2024/01/03.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 167-179"},"PeriodicalIF":4.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thematic analysis of cardiac arrest survivors' and their caregivers' psychosocial intervention needs.","authors":"Alexander M Presciutti, Bonnie Siry-Bove, Robert A Parker, Ona Wu, Jonathan Elmer, Michael W Donnino, Sarah M Perman, Ana-Maria Vranceanu","doi":"10.1016/j.genhosppsych.2024.10.015","DOIUrl":"https://doi.org/10.1016/j.genhosppsych.2024.10.015","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142498441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-cardiac chest pain: psychopathology, pathophysiology, and response to escitalopram.","authors":"Edwin S Meresh, Anton Shkundin, Erin T Tobin, John Piletz, Angelos Halaris","doi":"10.1016/j.genhosppsych.2024.10.013","DOIUrl":"https://doi.org/10.1016/j.genhosppsych.2024.10.013","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and measurement of post-exertional malaise in post-acute COVID-19 syndrome: A systematic review and meta-analysis","authors":"Yi An,&nbsp;Ziyu Guo,&nbsp;Jin Fan,&nbsp;Tingting Luo,&nbsp;Huimin Xu,&nbsp;Huiying Li,&nbsp;Xi Wu","doi":"10.1016/j.genhosppsych.2024.10.011","DOIUrl":"10.1016/j.genhosppsych.2024.10.011","url":null,"abstract":"<div><h3>Objective</h3><div>Post-exertional malaise (PEM) is a common and debilitating symptom of post-acute COVID-19 syndrome (PACS), and it is also included in the core outcome set for PACS. Our aims are to determine the prevalence of PEM in patients with PACS, and to review the measurement tools utilized in studies assessing PEM among these patients.</div></div><div><h3>Methods</h3><div>A systematic literature search was conducted up to 29 February 2024 across four databases: PubMed, EMBASE, Web of Science, and Cochrane Library. Studies were included if they evaluated PACS individuals who had at least one persistent symptom, with the mean or median follow-up duration of at least 3 months after COVID-19 diagnosis or hospital discharge, and specially reported on PEM or any measurement tools utilized to assess PEM. Data extraction and quality assessment were performed independently by two authors.</div></div><div><h3>Results</h3><div>After screening 953 articles, 12 studies comprising 2665 patients were included in the meta-analysis, and 16 studies were included in the narrative review. The pooled prevalence of PEM among PACS patients at 3 months or more after COVID-19 diagnosis was 0.55 (95 % CI, 0.38, 0.71). Moreover, narrative review identified seven questionnaires used to assess PEM in PACS individuals, with the DePaul Symptom Questionnaire–Post Exertional Malaise (DSQ-PEM) being the most frequently utilized instrument.</div></div><div><h3>Conclusion</h3><div>Our findings indicate that over half of the PACS individuals experience PEM, and seven questionnaires have been identified for researchers to assess PEM. It is imperative to develop effective intervention strategies to treat and alleviate the burden of PEM.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"91 ","pages":"Pages 130-142"},"PeriodicalIF":4.1,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142530766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}