M.E. Deichen Hansen, J. Day, A.M. Spitz, S. Goldfarb, J.S. Harman
{"title":"A national movement or just a ripple? Few outpatient perinatal visits engage in essential perinatal behavioral health screening practices","authors":"M.E. Deichen Hansen, J. Day, A.M. Spitz, S. Goldfarb, J.S. Harman","doi":"10.1016/j.genhosppsych.2025.05.012","DOIUrl":"10.1016/j.genhosppsych.2025.05.012","url":null,"abstract":"<div><h3>Objectives</h3><div>Perinatal behavioral health conditions are currently the leading cause of US maternal mortality. To prevent morbidity and mortality, obstetrics clinicians must screen for behavioral health conditions using a validated screener. However, many women's behavioral health conditions go undetected and untreated. This brief highlights the extent of the US health system's failure to adequately screen for critical perinatal health conditions.</div></div><div><h3>Methods</h3><div>Pooled data from the 2015–16, and 2018–19 National Ambulatory Medical Care Survey were generated to assess rates of screening for depression, alcohol use, substance use, and domestic violence during routine prenatal care visits.</div></div><div><h3>Results</h3><div>In the pooled 2015–2016 and 2018–2019 NAMCS sample (<em>n</em> = 1135) there were 82,986,275 weighted office visits for routine prenatal care. Clinicians most frequently identified as physicians. Screening data was nearly absent from the data, with domestic violence screenings being conducted most frequently at a reported 2.7 %.</div></div><div><h3>Conclusions</h3><div>This study found behavioral health screening tools are used infrequently during office visits for routine prenatal care. While many clinicians endorse at least some behavioral health screening practices, the adoption of these screenings in all healthcare settings has not occurred.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 16-17"},"PeriodicalIF":4.1,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xingbo Suo , Yang Zhang , Yi Zhang , Shenshuai Zhang , Jinguo Zhai , Maorong Hu
{"title":"The relationship between perceived stress and burnout among Chinese nurses: A moderated-mediation model","authors":"Xingbo Suo , Yang Zhang , Yi Zhang , Shenshuai Zhang , Jinguo Zhai , Maorong Hu","doi":"10.1016/j.genhosppsych.2025.05.010","DOIUrl":"10.1016/j.genhosppsych.2025.05.010","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 11-12"},"PeriodicalIF":4.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The rise of AI-generated content in academic writing: A cautionary note for commentaries and letters to the editor.","authors":"Stéphanie Baggio , Kali Tal","doi":"10.1016/j.genhosppsych.2025.05.008","DOIUrl":"10.1016/j.genhosppsych.2025.05.008","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 158-159"},"PeriodicalIF":4.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Ji , Karen Tu , John Wang , Debra A. Butt , Andrea S. Gershon , Jessica Gronsbell , Anthony D. Train , Braden O'Neill
{"title":"SARS-CoV-2 vaccination for individuals with schizophrenia in Ontario, Canada: A retrospective cohort study","authors":"Catherine Ji , Karen Tu , John Wang , Debra A. Butt , Andrea S. Gershon , Jessica Gronsbell , Anthony D. Train , Braden O'Neill","doi":"10.1016/j.genhosppsych.2025.05.009","DOIUrl":"10.1016/j.genhosppsych.2025.05.009","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 13-15"},"PeriodicalIF":4.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Semra Worrall , Naomi Carlisle , Olivia Pike , John Moffitt , Jenny Carter , Paul Christiansen , Asma Khalil , Sergio A. Silverio , Victoria Fallon
{"title":"The relationship between prenatal anxiety and gestational age: A systematic review","authors":"Semra Worrall , Naomi Carlisle , Olivia Pike , John Moffitt , Jenny Carter , Paul Christiansen , Asma Khalil , Sergio A. Silverio , Victoria Fallon","doi":"10.1016/j.genhosppsych.2025.05.007","DOIUrl":"10.1016/j.genhosppsych.2025.05.007","url":null,"abstract":"<div><div>Preterm birth poses a significant risk to short- and long-term infant health, and can have significant negative effects on maternal mental health. Increased levels of anxiety during pregnancy might be related to gestational age. Identifying potential risk factors for preterm birth may offer the opportunity for early intervention and reduce adverse outcomes. Ten databases, including empirical and grey literature, were searched. Articles were screened at title, abstract, and full-text review by two independent reviewers, and were quality assessed using the JBI critical appraisal tools. Forty-one studies were identified for inclusion in the review, published between 1990 and 2022. Data were narratively synthesised due to heterogeneity in study designs. Results of the data synthesis indicate there is an inverse relationship between anxiety and gestational age or preterm birth. This relationship may be dependent upon timing of assessment, and measure of anxiety used. Assessing anxiety at a single timepoint may not be as accurate as assessments across all three trimesters. Concerted efforts should be made to distinguish between spontaneous preterm birth and medically indicated preterm birth, as anxieties during pregnancy may present differently between the two groups. Future studies should consider the assessment of anxiety across trimesters to assess change in mood, as well as the use of pregnancy-specific measures alongside general measures to support intervention during pregnancy.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"96 ","pages":"Pages 1-10"},"PeriodicalIF":4.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144138077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional limitations and suicidal ideation: Independent, interactive, and cumulative associations in a nationally representative sample","authors":"Ying Cui","doi":"10.1016/j.genhosppsych.2025.05.006","DOIUrl":"10.1016/j.genhosppsych.2025.05.006","url":null,"abstract":"<div><h3>Background</h3><div>Suicidal ideation is a critical public health issue, often linked to functional limitations that hinder daily activities. However, the independent, interactive, and cumulative effects of specific types and quantities of functional limitations on suicidal ideation remain underexplored.</div></div><div><h3>Methods</h3><div>Data were analyzed from 12,263 U.S. adults in the National Health and Nutrition Examination Survey (NHANES, 2013–2018). Functional limitations were assessed across six domains: vision, hearing, cognitive, mobility, dressing/bathing, and errands. Multivariable logistic regression and interaction models were used to examine associations between functional limitations and suicidal ideation. Dose-response relationships were evaluated using restricted cubic spline regression.</div></div><div><h3>Results</h3><div>Vision (OR = 1.77, 95 % CI = 1.00–3.13), cognitive (OR = 5.52, 95 % CI = 3.63–8.39), and errand limitations (OR = 1.75, 95 % CI = 1.09–2.79) were independently associated with suicidal ideation. A significant interaction effect was observed between hearing and cognitive limitations, with the co-occurrence amplifying suicidal ideation risk (OR = 5.80, 95 % CI = 3.84–8.78). Additionally, a dose-response relationship was found, with individuals experiencing ≥5 limitations having the highest risk.</div></div><div><h3>Conclusions</h3><div>Functional limitations, particularly cognitive and errand-related impairments, are strongly associated with suicidal ideation. Interaction effects and cumulative impacts underscore the need for integrated mental and physical healthcare approaches. Tailored interventions targeting specific limitations and addressing cumulative burdens may mitigate suicidal ideation in this vulnerable population.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 148-157"},"PeriodicalIF":4.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah F. Allen , Albert M. van Hemert , Margot W.M. de Waal , Christina van der Feltz-Cornelis
{"title":"Exploration of the factor structure of the physical symptoms questionnaire (PSQ-51). Comparisons between Dutch and English samples","authors":"Sarah F. Allen , Albert M. van Hemert , Margot W.M. de Waal , Christina van der Feltz-Cornelis","doi":"10.1016/j.genhosppsych.2025.05.002","DOIUrl":"10.1016/j.genhosppsych.2025.05.002","url":null,"abstract":"<div><div>The Physical Symptoms Questionnaire (PSQ-51) is a Dutch-language self-report tool listing 51 physical symptoms that may occur in patients with known medical conditions, somatic symptom disorders and the general population. However, the tool is currently only available in Dutch and is yet to be translated or validated into English for utility with English-speaking populations. This study aimed to translate and validate an English version of the tool and determine the PSQ-51's factor structure in both Dutch and UK samples. An English version was translated and then validated through back-translation and refined for clarity. Data from three Dutch samples (general population [<em>n</em> = 1699], general practice[<em>n</em> = 775], and psychiatric outpatients[<em>n</em> = 1404]) and one UK general population sample (<em>n</em> = 294) were then analysed to explore the factor structure. An iterative exploratory factor analysis (EFA) on the Dutch psychiatric sample revealed a seven-factor solution including symptom clusters: General Malaise, Autonomic, Musculoskeletal, Gastrointestinal, Loss of Function, Hot Flushes, and Urogenital symptoms. Confirmatory factor analysis (CFA) tested this model across the Dutch and UK samples, with mixed results for fit indices, although good internal reliability was demonstrated. Findings indicate partial cross-cultural consistency in the factor structure. Substantial differences in symptom prevalence between Dutch and UK population samples were observed, possibly due to cultural and situational factors. The PSQ-51 shows promise for assessing somatic symptom burden, for example in multimorbidity or in complex somatic symptom disorders, where it may enhance clinical consultations by identifying symptoms to address clinical complexity. Further research is needed to explore its applicability in diverse populations and refine its factor structure for broader clinical utility.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 140-147"},"PeriodicalIF":4.1,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143947572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Luccarelli , Jacqueline A. Clauss , Tasia York , Isaac Baldwin , Simon Vandekar , Trey McGonigle , Gregory Fricchione , Catherine Fuchs , Joshua R. Smith
{"title":"Hospitalizations for pediatric catatonia in neurodivergent and neurotypical patients","authors":"James Luccarelli , Jacqueline A. Clauss , Tasia York , Isaac Baldwin , Simon Vandekar , Trey McGonigle , Gregory Fricchione , Catherine Fuchs , Joshua R. Smith","doi":"10.1016/j.genhosppsych.2025.05.003","DOIUrl":"10.1016/j.genhosppsych.2025.05.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Catatonia is a neuropsychiatric disorder that occurs in pediatric patients with a range of associated medical, psychiatric, and neurodevelopmental disorders (NDDs). This study describes hospital care of pediatric catatonia patients and compares treatments for neurotypical patients and those with NDDs.</div></div><div><h3>Methods</h3><div>Retrospective cohort study from 1/1/2018 to 6/1/2023 of two academic medical centers of patients aged 18 and younger with catatonia. Patients were retrospectively assessed using the clinical global impressions-improvement (CGI-I) by two independent reviewers.</div></div><div><h3>Results</h3><div>One hundred sixty-five patients were hospitalized for catatonia, of whom 50.3 % had an NDD. Median age was 15. One hundred sixty-four patients were treated with a benzodiazepine, with a median maximum 24-hour dose of 6 mg lorazepam-equivalents, which did not differ for patients with and without NDDs. Electroconvulsive therapy (ECT) was utilized in 14.5 % of patients. Median length of medical hospitalization was 5 days and hospitalizations were longer in neurotypical patients than in patients with NDDs. In an ordinal regression model, the probability of observing at least “much improvement” (CGI < 3) was 88.3 % (95 % CI: 82.4 % to 92.3 %), with patients with a non-medical primary diagnosis and an NDD having a lower odds of response than non-medical primary diagnosis without an NDD.</div></div><div><h3>Conclusions</h3><div>The probability of patients achieving a CGI-I score indicating at least “much improvement” was 88.3 %. Administered benzodiazepine dose and ECT treatment were similar for all patients, but neurotypical patients had longer hospitalizations than those with NDDs and had a higher odds of a more favorable clinical response for patients with non-medical primary diagnoses. Research under controlled conditions is needed to optimize and endure equitable catatonia treatment in youth.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 133-139"},"PeriodicalIF":4.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143943537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qisheng Cheng , Yuxin Ran , Xiaolong Mo , Rui Xiao , Dian He , Siyi Guo , Haiyang Wang , Lanxiang Liu , Peng Xie
{"title":"The efficacy and acceptability of Lactobacillus reuteri for the treatment of depression: A systematic review and meta-analysis","authors":"Qisheng Cheng , Yuxin Ran , Xiaolong Mo , Rui Xiao , Dian He , Siyi Guo , Haiyang Wang , Lanxiang Liu , Peng Xie","doi":"10.1016/j.genhosppsych.2025.05.004","DOIUrl":"10.1016/j.genhosppsych.2025.05.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Some preclinical and clinical studies have demonstrated the positive effect of <em>Lactobacillus reuteri</em> (<em>L. reuteri</em>) supplementation on depressive symptoms. We conducted an updated systematic review on this topic.</div></div><div><h3>Method</h3><div>PubMed, EMBASE, Cochrane, Web of Science, and international trial registries were searched. We included randomized controlled trials (RCTs) and animal experiments on the use of mixed probiotics containing L. <em>reuteri</em> in the treatment of depression. Analyses were done using Review Manager version 5.4 and Stata 18.0.</div></div><div><h3>Results</h3><div>In total, 12 RCTs including 1258 patients were included. The efficacy of the mixed probiotics containing L. <em>reuteri</em> in the treatment of depression was superior to the control group (SMD: -0.44, 95 %CI: −0.72 to −0.16). In terms of acceptability, there was no significant difference between the probiotic and control groups (OR: 1.04, 95 %CI: 0.75 to 1.45). In 9 animal experiments, mixed probiotics containing L. <em>reuteri</em> improved the symptoms of anxiety and depression. Subgroup analyses showed patients using multi-strain interventions (SMD: -0.56, 95 %CI: −0.97 to −0.15), having depressive symptoms (SMD: -0.39, 95 %CI: −0.74 to −0.03), and other clinical populations (SMD: -0.59, 95 %CI: −1.06 to −0.13), age < 60 years (SMD: -0.52, 95 %CI: −0.88 to −0.15), female patients (SMD: -0.45, 95 %CI: −0.78 to −0.13) may benefit more.</div></div><div><h3>Conclusion</h3><div>Mixed probiotics containing L. <em>reuteri</em> ameliorated depressive symptoms in patients and depression-like behaviors in animals. Combined microbiota seems to be more effective than single strain intervention in the treatment of depression. Patients with depressive symptoms, other clinical populations, age < 60 years, female patients may benefit more from probiotics. <em>L. reuteri</em> alone did not improve depressive symptoms.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 122-132"},"PeriodicalIF":4.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of virtual reality-based rehabilitation on poststroke depression: A systematic review and meta-analysis","authors":"Ying Wei, Hao Tian, Cungen Ma, Lijuan Song","doi":"10.1016/j.genhosppsych.2025.05.001","DOIUrl":"10.1016/j.genhosppsych.2025.05.001","url":null,"abstract":"<div><h3>Background</h3><div>Depression is the most common neuropsychiatric sequela of stroke, negatively affecting functional recovery and quality of life. Although virtual reality-based rehabilitation (VRBR) is an effective intervention in stroke rehabilitation, its efficacy in treating poststroke depression (PSD) remains unclear.</div></div><div><h3>Objectives</h3><div>To evaluate the treatment effect of VRBR on PSD.</div></div><div><h3>Data sources and methods</h3><div>Six medical databases were systematically searched from inception to May 31, 2024, with an update on October 5, 2024. Potentially eligible studies were screened against the inclusion and exclusion criteria. Review Manager 5.4 and Stata 14.0 were used to conduct statistical analysis.</div></div><div><h3>Results</h3><div>Twelve studies published between 2015 and 2024 were included. The pooled results revealed that VRBR significantly reduced depression scores among poststroke patients [SMD = −0.56, 95 % CI (−0.90,<!--> <!-->−0.23), <em>P</em> = 0.001]. Subgroup analyses suggested numerically greater improvements in patients with a mean age < 60 years and those receiving ≥20 intervention sessions, though between-subgroup differences were not statistically significant.</div></div><div><h3>Conclusion</h3><div>VRBR may be a promising therapy for PSD. However, methodologically rigorous studies are needed to further confirm its efficacy and safety.</div></div><div><h3>Trial registration</h3><div>PROSPERO, CRD42024550019.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 114-121"},"PeriodicalIF":4.1,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}