{"title":"Trauma as a predictor of remission and SSRI response in major depression","authors":"Rikas Saputra , Yenni Lidyawati , Rani Mega Putri , Sigit Dwi Sucipto","doi":"10.1016/j.genhosppsych.2024.12.025","DOIUrl":"10.1016/j.genhosppsych.2024.12.025","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 93-94"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding years of life lost to psychiatric disorders: A review and recommendations for further research","authors":"Rikas Saputra , Yenni Lidyawati , Rani Mega Putri , Kiki Mariah , Isnaria Rizki Hayati , Sigit Dwi Sucipto","doi":"10.1016/j.genhosppsych.2024.12.023","DOIUrl":"10.1016/j.genhosppsych.2024.12.023","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 62-63"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pao-Huan Chen , Cheng-Yi Hsiao , Jiunn-Kae Wang , Hsiao-Lun Ku , Kuo-Hsuan Chung , Shang-Ying Tsai
{"title":"Association between allostatic load and cardiac structural and functional abnormalities in young adults with serious mental disorders","authors":"Pao-Huan Chen , Cheng-Yi Hsiao , Jiunn-Kae Wang , Hsiao-Lun Ku , Kuo-Hsuan Chung , Shang-Ying Tsai","doi":"10.1016/j.genhosppsych.2024.12.011","DOIUrl":"10.1016/j.genhosppsych.2024.12.011","url":null,"abstract":"<div><h3>Objective</h3><div>Allostatic load refers to the pathophysiological consequences of uncompensated adaptation to chronic stress. Few studies have investigated the effect of allostatic load on cardiac health in patients with serious mental disorders (SMDs), a population at high risk of cardiac mortality. Herein we evaluated associations between allostatic load and cardiac structure and function in young adults with SMDs.</div></div><div><h3>Method</h3><div>A total of 106 participants aged younger than 45 years underwent echocardiographic study, blood biochemistry examination, and blood cell count analysis. Echocardiographic imaging was conducted in accordance with recommendations of the American Society of Echocardiography and European Association of Cardiovascular Imaging. Allostatic load index was calculated using 15 measures representing cardiovascular, metabolic, and inflammatory or oxidative stress markers.</div></div><div><h3>Results</h3><div>The SMD group exhibited a significantly higher allostatic load index than did control (Cohen's <em>d</em> = 0.59). Additionally, they exhibited a greater left ventricular relative wall thickness (LVRWT, Cohen's <em>d</em> = 0.39) and a less favorable mitral valve E/A ratio (Cohen's <em>d</em> = 0.31), left ventricular ejection fraction (Cohen's <em>d</em> = 0.51), and global longitudinal strain (Cohen's <em>d</em> = 0.71). After demographic and clinical characteristics were adjusted for, multiple linear regression revealed that allostatic load index was positively associated with LVRWT (<em>β</em> = 0.255) and negatively associated with mitral valve E/A ratio (<em>β</em> = −0.247) in the SMD group.</div></div><div><h3>Conclusions</h3><div>This is the first study to suggest that allostatic load may play a critical role in accelerated adverse cardiac remodeling among young patients with SMDs. Future studies should elucidate the underlying mechanisms.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 40-45"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Runtang Meng , Nongnong Yang , Yi Luo , Ciarán O'Driscoll , Haiyan Ma , Alice M. Gregory , Joseph M. Dzierzewski
{"title":"Detecting psychometric and diagnostic performance of the RU_SATED v2.0 multidimensional sleep health scale in community-dwelling adults combining exploratory graph analysis and ROC analysis","authors":"Runtang Meng , Nongnong Yang , Yi Luo , Ciarán O'Driscoll , Haiyan Ma , Alice M. Gregory , Joseph M. Dzierzewski","doi":"10.1016/j.genhosppsych.2024.12.001","DOIUrl":"10.1016/j.genhosppsych.2024.12.001","url":null,"abstract":"<div><h3>Objective</h3><div>The RU_SATED scale is increasingly used across the globe to measure sleep health. However, there is a lack of consensus around its psychometric and diagnostic performance. We conducted an empirical investigation into the psychometrics of the Chinese version of the RU_SATED (RU_SATED-C) scale, with a focus on structural validity and diagnostic performance.</div></div><div><h3>Methods</h3><div>1171 adults were enrolled from three communities in Hangzhou, China in July 2022. The dataset was spilt in half, and we ran a bootstrapped exploratory graph analysis (bootEGA) in one half and a confirmatory factor analysis (CFA) in the other half to assess structural validity. Correlations with insomnia, wellness, anxiety, and depression symptoms were examined in order to assess concurrent validity; and Cronbach's α and McDonald's ω were calculated to assess internal consistency. Additionally, a Receiver Operating Characteristic (ROC) analysis established and externally validated the optimal score for identifying insomnia symptoms.</div></div><div><h3>Results</h3><div>A one-dimensional structure, as identified by bootEGA, was corroborated in the CFA [comparative fit index = 0.934, root mean square error of approximation = 0.088, standardized root mean square residual = 0.051]. A moderate correlation was shown with insomnia symptoms, while weak correlations were observed with wellness, anxiety, and depression symptoms. The RU_SATED-C scale displayed sub-optimal internal consistency where coefficients dropped if any item was removed. A recommended cutoff score of ≤13 was derived for probable insomnia with a satisfactory diagnostic performance.</div></div><div><h3>Conclusion</h3><div>The RU_SATED-C scale displayed a one-dimensional model, along with adequate concurrent validity, internal consistency, and diagnostic performance. Further work necessitates multi-scenario testing and additional validation using objective sleep assessments.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 75-83"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robin M. Masheb , Adam Batten , Sarah E. Siegel , Joy Huggins , Alison Marsh , Jennifer L. Snow , Lindsay F. Munro , Dawne Vogt , Marney A. White , Shira Maguen
{"title":"Development and validation of the BRief Eating Disorder Screener (BREDS) for US veterans in healthcare and community settings","authors":"Robin M. Masheb , Adam Batten , Sarah E. Siegel , Joy Huggins , Alison Marsh , Jennifer L. Snow , Lindsay F. Munro , Dawne Vogt , Marney A. White , Shira Maguen","doi":"10.1016/j.genhosppsych.2024.12.021","DOIUrl":"10.1016/j.genhosppsych.2024.12.021","url":null,"abstract":"<div><h3>Objective</h3><div>To develop a Diagnostic and Statistical Manual of Mental Disorders (DSM-5) eating disorder screener.</div></div><div><h3>Method</h3><div>Veterans enrolled in VA healthcare (<em>N</em> = 344) completed a survey of screening items and established measures. A validation subset (<em>n</em> = 166) participated in diagnostic interviews to confirm an eating disorder diagnosis. Items most predictive of diagnosis were included or adapted for a confirmatory national survey (<em>N</em> = 405).</div></div><div><h3>Results</h3><div>Item selection models using machine learning techniques resulted in a five-item screen with good sensitivity, specificity and area under the curve (0.75, 0.87, and 0.83). Items included: (1) Do you do things to rid your body or stomach of calories or food (vomiting, excessive exercise, laxative or diuretic use, or something else)? (2) Do you ever eat an extremely large amount of food without thinking? (3) Are you or other people in your life concerned about a recent change in your weight? (4) Is your weight or shape one of the main ways you judge yourself? (5) Do you need to eat in order to get back to sleep when you wake up at night?</div></div><div><h3>Conclusion</h3><div>The 5-item BRief Eating Disorder Screener (BREDS) is the first screen developed and validated for a broad range of DSM-5 eating disorder diagnoses.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"93 ","pages":"Pages 1-8"},"PeriodicalIF":4.1,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}