General hospital psychiatry最新文献

{"title":"Functional limitations and suicidal ideation: Independent, interactive, and cumulative associations in a nationally representative sample","authors":"Ying Cui","doi":"10.1016/j.genhosppsych.2025.05.006","DOIUrl":"10.1016/j.genhosppsych.2025.05.006","url":null,"abstract":"<div><h3>Background</h3><div>Suicidal ideation is a critical public health issue, often linked to functional limitations that hinder daily activities. However, the independent, interactive, and cumulative effects of specific types and quantities of functional limitations on suicidal ideation remain underexplored.</div></div><div><h3>Methods</h3><div>Data were analyzed from 12,263 U.S. adults in the National Health and Nutrition Examination Survey (NHANES, 2013–2018). Functional limitations were assessed across six domains: vision, hearing, cognitive, mobility, dressing/bathing, and errands. Multivariable logistic regression and interaction models were used to examine associations between functional limitations and suicidal ideation. Dose-response relationships were evaluated using restricted cubic spline regression.</div></div><div><h3>Results</h3><div>Vision (OR = 1.77, 95 % CI = 1.00–3.13), cognitive (OR = 5.52, 95 % CI = 3.63–8.39), and errand limitations (OR = 1.75, 95 % CI = 1.09–2.79) were independently associated with suicidal ideation. A significant interaction effect was observed between hearing and cognitive limitations, with the co-occurrence amplifying suicidal ideation risk (OR = 5.80, 95 % CI = 3.84–8.78). Additionally, a dose-response relationship was found, with individuals experiencing ≥5 limitations having the highest risk.</div></div><div><h3>Conclusions</h3><div>Functional limitations, particularly cognitive and errand-related impairments, are strongly associated with suicidal ideation. Interaction effects and cumulative impacts underscore the need for integrated mental and physical healthcare approaches. Tailored interventions targeting specific limitations and addressing cumulative burdens may mitigate suicidal ideation in this vulnerable population.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 148-157"},"PeriodicalIF":4.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144071316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of the factor structure of the physical symptoms questionnaire (PSQ-51). Comparisons between Dutch and English samples","authors":"Sarah F. Allen ,&nbsp;Albert M. van Hemert ,&nbsp;Margot W.M. de Waal ,&nbsp;Christina van der Feltz-Cornelis","doi":"10.1016/j.genhosppsych.2025.05.002","DOIUrl":"10.1016/j.genhosppsych.2025.05.002","url":null,"abstract":"<div><div>The Physical Symptoms Questionnaire (PSQ-51) is a Dutch-language self-report tool listing 51 physical symptoms that may occur in patients with known medical conditions, somatic symptom disorders and the general population. However, the tool is currently only available in Dutch and is yet to be translated or validated into English for utility with English-speaking populations. This study aimed to translate and validate an English version of the tool and determine the PSQ-51's factor structure in both Dutch and UK samples. An English version was translated and then validated through back-translation and refined for clarity. Data from three Dutch samples (general population [<em>n</em> = 1699], general practice[<em>n</em> = 775], and psychiatric outpatients[<em>n</em> = 1404]) and one UK general population sample (<em>n</em> = 294) were then analysed to explore the factor structure. An iterative exploratory factor analysis (EFA) on the Dutch psychiatric sample revealed a seven-factor solution including symptom clusters: General Malaise, Autonomic, Musculoskeletal, Gastrointestinal, Loss of Function, Hot Flushes, and Urogenital symptoms. Confirmatory factor analysis (CFA) tested this model across the Dutch and UK samples, with mixed results for fit indices, although good internal reliability was demonstrated. Findings indicate partial cross-cultural consistency in the factor structure. Substantial differences in symptom prevalence between Dutch and UK population samples were observed, possibly due to cultural and situational factors. The PSQ-51 shows promise for assessing somatic symptom burden, for example in multimorbidity or in complex somatic symptom disorders, where it may enhance clinical consultations by identifying symptoms to address clinical complexity. Further research is needed to explore its applicability in diverse populations and refine its factor structure for broader clinical utility.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 140-147"},"PeriodicalIF":4.1,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143947572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospitalizations for pediatric catatonia in neurodivergent and neurotypical patients","authors":"James Luccarelli ,&nbsp;Jacqueline A. Clauss ,&nbsp;Tasia York ,&nbsp;Isaac Baldwin ,&nbsp;Simon Vandekar ,&nbsp;Trey McGonigle ,&nbsp;Gregory Fricchione ,&nbsp;Catherine Fuchs ,&nbsp;Joshua R. Smith","doi":"10.1016/j.genhosppsych.2025.05.003","DOIUrl":"10.1016/j.genhosppsych.2025.05.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Catatonia is a neuropsychiatric disorder that occurs in pediatric patients with a range of associated medical, psychiatric, and neurodevelopmental disorders (NDDs). This study describes hospital care of pediatric catatonia patients and compares treatments for neurotypical patients and those with NDDs.</div></div><div><h3>Methods</h3><div>Retrospective cohort study from 1/1/2018 to 6/1/2023 of two academic medical centers of patients aged 18 and younger with catatonia. Patients were retrospectively assessed using the clinical global impressions-improvement (CGI-I) by two independent reviewers.</div></div><div><h3>Results</h3><div>One hundred sixty-five patients were hospitalized for catatonia, of whom 50.3 % had an NDD. Median age was 15. One hundred sixty-four patients were treated with a benzodiazepine, with a median maximum 24-hour dose of 6 mg lorazepam-equivalents, which did not differ for patients with and without NDDs. Electroconvulsive therapy (ECT) was utilized in 14.5 % of patients. Median length of medical hospitalization was 5 days and hospitalizations were longer in neurotypical patients than in patients with NDDs. In an ordinal regression model, the probability of observing at least “much improvement” (CGI &lt; 3) was 88.3 % (95 % CI: 82.4 % to 92.3 %), with patients with a non-medical primary diagnosis and an NDD having a lower odds of response than non-medical primary diagnosis without an NDD.</div></div><div><h3>Conclusions</h3><div>The probability of patients achieving a CGI-I score indicating at least “much improvement” was 88.3 %. Administered benzodiazepine dose and ECT treatment were similar for all patients, but neurotypical patients had longer hospitalizations than those with NDDs and had a higher odds of a more favorable clinical response for patients with non-medical primary diagnoses. Research under controlled conditions is needed to optimize and endure equitable catatonia treatment in youth.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 133-139"},"PeriodicalIF":4.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143943537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy and acceptability of Lactobacillus reuteri for the treatment of depression: A systematic review and meta-analysis","authors":"Qisheng Cheng ,&nbsp;Yuxin Ran ,&nbsp;Xiaolong Mo ,&nbsp;Rui Xiao ,&nbsp;Dian He ,&nbsp;Siyi Guo ,&nbsp;Haiyang Wang ,&nbsp;Lanxiang Liu ,&nbsp;Peng Xie","doi":"10.1016/j.genhosppsych.2025.05.004","DOIUrl":"10.1016/j.genhosppsych.2025.05.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Some preclinical and clinical studies have demonstrated the positive effect of <em>Lactobacillus reuteri</em> (<em>L. reuteri</em>) supplementation on depressive symptoms. We conducted an updated systematic review on this topic.</div></div><div><h3>Method</h3><div>PubMed, EMBASE, Cochrane, Web of Science, and international trial registries were searched. We included randomized controlled trials (RCTs) and animal experiments on the use of mixed probiotics containing L. <em>reuteri</em> in the treatment of depression. Analyses were done using Review Manager version 5.4 and Stata 18.0.</div></div><div><h3>Results</h3><div>In total, 12 RCTs including 1258 patients were included. The efficacy of the mixed probiotics containing L. <em>reuteri</em> in the treatment of depression was superior to the control group (SMD: -0.44, 95 %CI: −0.72 to −0.16). In terms of acceptability, there was no significant difference between the probiotic and control groups (OR: 1.04, 95 %CI: 0.75 to 1.45). In 9 animal experiments, mixed probiotics containing L. <em>reuteri</em> improved the symptoms of anxiety and depression. Subgroup analyses showed patients using multi-strain interventions (SMD: -0.56, 95 %CI: −0.97 to −0.15), having depressive symptoms (SMD: -0.39, 95 %CI: −0.74 to −0.03), and other clinical populations (SMD: -0.59, 95 %CI: −1.06 to −0.13), age &lt; 60 years (SMD: -0.52, 95 %CI: −0.88 to −0.15), female patients (SMD: -0.45, 95 %CI: −0.78 to −0.13) may benefit more.</div></div><div><h3>Conclusion</h3><div>Mixed probiotics containing L. <em>reuteri</em> ameliorated depressive symptoms in patients and depression-like behaviors in animals. Combined microbiota seems to be more effective than single strain intervention in the treatment of depression. Patients with depressive symptoms, other clinical populations, age &lt; 60 years, female patients may benefit more from probiotics. <em>L. reuteri</em> alone did not improve depressive symptoms.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 122-132"},"PeriodicalIF":4.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of virtual reality-based rehabilitation on poststroke depression: A systematic review and meta-analysis","authors":"Ying Wei,&nbsp;Hao Tian,&nbsp;Cungen Ma,&nbsp;Lijuan Song","doi":"10.1016/j.genhosppsych.2025.05.001","DOIUrl":"10.1016/j.genhosppsych.2025.05.001","url":null,"abstract":"<div><h3>Background</h3><div>Depression is the most common neuropsychiatric sequela of stroke, negatively affecting functional recovery and quality of life. Although virtual reality-based rehabilitation (VRBR) is an effective intervention in stroke rehabilitation, its efficacy in treating poststroke depression (PSD) remains unclear.</div></div><div><h3>Objectives</h3><div>To evaluate the treatment effect of VRBR on PSD.</div></div><div><h3>Data sources and methods</h3><div>Six medical databases were systematically searched from inception to May 31, 2024, with an update on October 5, 2024. Potentially eligible studies were screened against the inclusion and exclusion criteria. Review Manager 5.4 and Stata 14.0 were used to conduct statistical analysis.</div></div><div><h3>Results</h3><div>Twelve studies published between 2015 and 2024 were included. The pooled results revealed that VRBR significantly reduced depression scores among poststroke patients [SMD = −0.56, 95 % CI (−0.90,<!--> <!-->−0.23), <em>P</em> = 0.001]. Subgroup analyses suggested numerically greater improvements in patients with a mean age &lt; 60 years and those receiving ≥20 intervention sessions, though between-subgroup differences were not statistically significant.</div></div><div><h3>Conclusion</h3><div>VRBR may be a promising therapy for PSD. However, methodologically rigorous studies are needed to further confirm its efficacy and safety.</div></div><div><h3>Trial registration</h3><div>PROSPERO, CRD42024550019.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 114-121"},"PeriodicalIF":4.1,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The overlooked reality of Misophonia: Urging scientific and clinical inquiry","authors":"Raazia Hasan ,&nbsp;Fnu Mubashirah","doi":"10.1016/j.genhosppsych.2025.04.013","DOIUrl":"10.1016/j.genhosppsych.2025.04.013","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 78-79"},"PeriodicalIF":4.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large decrease in posttraumatic stress disorder severity and cardiovascular disease outcomes","authors":"Joanne Salas ,&nbsp;Poorva Sheth ,&nbsp;Beth E. Cohen ,&nbsp;Kenneth E. Freedland ,&nbsp;Allan S. Jaffe ,&nbsp;Paula P. Schnurr ,&nbsp;Matthew Friedman ,&nbsp;Patrick J. Lustman ,&nbsp;Jeffrey F. Scherrer","doi":"10.1016/j.genhosppsych.2025.04.011","DOIUrl":"10.1016/j.genhosppsych.2025.04.011","url":null,"abstract":"<div><h3>Background</h3><div>Posttraumatic stress disorder (PTSD) is associated with risk for cardiovascular disease (CVD). Improved physical health often follows large decreases in PTSD severity, but it is not known if better CVD outcomes follow PTSD improvement in patients with comorbid PTSD and CVD.</div></div><div><h3>Methods</h3><div>De-identified medical record data between 2011 and 2022 was used to create a cohort of 7120 Veterans Health Administration patients with PTSD and comorbid CVD. The exposure was clinically meaningful PTSD improvement defined as ≥20-point PTSD Checklist (PCL) decrease. Entropy balance controlled for confounding. Cox proportional hazard models estimated the association between clinically meaningful PCL decrease and CVD outcomes: myocardial infarction or revascularization procedure, all-cause mortality, and stroke.</div></div><div><h3>Results</h3><div>About half (52.2 %) of the sample was 65–80 years of age, 95.5 % were male, 17.3 % identified as Black and 79.2 % as White race. Clinically meaningful PTSD improvement occurred for 20.4 % of patients. After controlling for confounding, those with vs. without clinically meaningful PTSD improvement did not significantly differ on risk for myocardial infarction or revascularization procedure (HR = 1.07; 95 %CI:0.94–1.20), all-cause mortality (HR = 1.02; 95 %CI:0.89–1.17), and stroke (HR = 1.10; 95 %CI:0.96–1.26). Neither race, age nor depression significantly modified the association of PTSD improvement and risk for adverse CVD outcomes.</div></div><div><h3>Conclusions</h3><div>In this sample of veterans, large reductions in PTSD severity were not associated with better or worse CVD outcomes. Research is needed to determine if clinically meaningful PTSD improvement and the lack of association with CVD outcomes is seen in other populations of patients with comorbid PTSD and CVD.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 102-108"},"PeriodicalIF":4.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnic disparities in rapid tranquillisation use and explanations in adult mental health emergency settings?","authors":"Martin Locht Pedersen ,&nbsp;Alessio Bricca ,&nbsp;John Baker ,&nbsp;Ole Schjerning ,&nbsp;Trine Munk-Olsen ,&nbsp;Frederik Alkier Gildberg","doi":"10.1016/j.genhosppsych.2025.04.014","DOIUrl":"10.1016/j.genhosppsych.2025.04.014","url":null,"abstract":"<div><h3>Objective</h3><div>Ethnicity is a frequently reported risk factor for rapid tranquillisation (RT) use in mental health. We aimed to investigate the association between ethnicity and RT use in adult mental health emergency settings and explore potential explanations for the relationship between ethnicity and RT use in these settings.</div></div><div><h3>Methods</h3><div>Studies were included if they reported the association between ethnicity and RT use in adult mental health emergency settings. Searches were conducted across six databases and in grey sources and references until 15 April 2024. A narrative synthesis was performed and, in addition, a random-effects model was used for meta-analysis, with odds ratio as the measure. GRADE was applied to evaluate the overall certainty of evidence. Potential explanations for RT use in relation to ethnicity were also synthesised narratively.</div></div><div><h3>Results</h3><div>Five studies from Norway (<em>n</em> = 1), Spain (n = 1) and the United States (<em>n</em> = 3) were included (14,777 individuals). Multiple classifications of ethnicity were used, with White, non-Hispanic and native-born serving as the ethnic majority group compared to ethnic minority counterparts. Overall, ethnic minorities in adult mental health emergency settings were non-statistically more likely to receive RT than ethnic majority populations. The overall certainty of evidence was deemed as low according to GRADE.</div></div><div><h3>Conclusion</h3><div>While RT use was not statistically significantly higher among ethnic minorities overall, Black individuals, as a specific ethnic group, had significantly increased odds of experiencing RT compared to ethnic majority populations. Additional research is necessary to confirm these findings and better understand the reasons behind these disparities through valid explanations.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of multimorbidity on suicidal behaviour: A systematic review and meta-analysis","authors":"Richmond Opoku ,&nbsp;Adwoa Konadu Mensah ,&nbsp;Mintu Nath","doi":"10.1016/j.genhosppsych.2025.04.008","DOIUrl":"10.1016/j.genhosppsych.2025.04.008","url":null,"abstract":"<div><h3>Introduction</h3><div>Multimorbidity, the co-occurrence of multiple health conditions, is increasingly recognised as a significant public health concern. While the association between multimorbidity and suicidal thoughts is well-documented, its relationship with suicidal behaviour remains underexplored. This study aims to quantify the association between multimorbidity and both suicide attempts and suicide mortality.</div></div><div><h3>Methods</h3><div>We searched Medline, PsycINFO, and Scopus databases for studies published from January 1990 up to July 2024. We applied prespecified eligibility criteria to select studies for inclusion. To assess the risk of bias, we used the Mixed Methods Appraisal Tool. We conducted meta-analyses using random-effects models and assessed heterogeneity with Cochran's <em>Q</em> and <em>I</em>^<em>2</em> statistics. We evaluated publication bias using funnel plots and Egger's test. Sub-group analysis was conducted incorporating potential moderator variables.</div></div><div><h3>Results</h3><div>Out of 2202 identified records, 38 studies were included in the analysis. Participants with multimorbidity were over five times more likely to attempt suicide compared to those without multimorbidity (pooled odds ratio [OR] = 5.31; 95 % confidence interval [CI] = 3.98, 7.09; <em>I</em>^<em>2</em> = 94.9 %). Multimorbidity was associated with an 83 % increased likelihood of suicide mortality (pooled OR = 1.83; 95 % CI = 1.21, 2.77; <em>I</em>^<em>2</em> = 99.9 %). Mental multimorbidity was associated with the highest odds of suicide attempts (OR = 6.96; 95 % CI = 4.94, 9.81; <em>I</em>^<em>2</em> = 81.8 %), with higher odds also observed in studies with single disease comparator (OR = 6.16; 95 % CI = 3.68, 10.31; <em>I</em>^<em>2</em> = 95.5 %), and across both high income and low-middle income regions. For suicide mortality, significant associations were found in studies assessing physical-mental multimorbidity (OR = 2.32; 95 % CI = 1.14, 4.71; <em>I</em>^<em>2</em> = 99.8 %), studies from Europe/USA and Asia, and those using a mixed comparator group, with additional significant effects noted by study design, publication year, covariate adjustment, and risk of bias.</div></div><div><h3>Conclusions</h3><div>Multimorbidity significantly increases the risk of both suicide attempts and suicide mortality. We recommend enhanced suicide risk assessment among patients with multiple chronic conditions, especially when mental health diagnoses are present.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 80-92"},"PeriodicalIF":4.1,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence of physical deconditioning during psychiatric hospitalization in a Veteran sample","authors":"Laura E. Ong ,&nbsp;Gilbert Ramirez ,&nbsp;Steven H. Woodward","doi":"10.1016/j.genhosppsych.2025.04.009","DOIUrl":"10.1016/j.genhosppsych.2025.04.009","url":null,"abstract":"<div><div>Prior observations of low physical activity in psychiatric inpatient care suggest a risk of physical deconditioning, but to date no studies have explicitly investigated this possibility by measuring change in cardiovascular fitness over the course of hospitalization. The present study used mattress actigraphy to obtain a passive measure of sleep heart rate (sHR) among a sample of 111 male Veterans receiving treatment for PTSD at the VA Palo Alto Health Care System Trauma Recovery Program (TRP). A linear mixed-effect regression model indicated that sHR significantly increased over nights hospitalized, though this effect was attenuated among those who participated at least once in a voluntary cycling program. Conversely, higher BMI at intake was associated with greater increases in sHR over nights. These findings provide evidence of physical deconditioning in the context of residential psychiatric treatment, while suggesting that at least some patients are protected from its impacts. Whole health interventions that promote exercise in tandem with mental health treatment may help to counteract physical deconditioning in psychiatric inpatient settings and should be designed to support patients of diverse fitness levels.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"95 ","pages":"Pages 109-113"},"PeriodicalIF":4.1,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}