基于虚拟现实的康复对脑卒中后抑郁的影响：一项系统综述和荟萃分析

IF 4.1 2区医学 Q1 PSYCHIATRY

General hospital psychiatry Pub Date : 2025-05-03 DOI:10.1016/j.genhosppsych.2025.05.001

Ying Wei, Hao Tian, Cungen Ma, Lijuan Song

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引用次数: 0

摘要

抑郁症是中风最常见的神经精神后遗症，对功能恢复和生活质量产生负面影响。尽管基于虚拟现实的康复（VRBR）是一种有效的卒中康复干预手段，但其对卒中后抑郁（PSD）的治疗效果尚不清楚。目的评价VRBR治疗PSD的疗效。数据来源与方法对6个医学数据库进行系统检索，检索时间为建库至2024年5月31日，更新时间为2024年10月5日。根据纳入和排除标准筛选可能符合条件的研究。采用Review Manager 5.4和Stata 14.0进行统计分析。结果纳入2015 - 2024年间发表的12项研究。综合结果显示，VRBR显著降低脑卒中后患者的抑郁评分[SMD = - 0.56, 95% CI (- 0.90, - 0.23), P = 0.001]。亚组分析表明，平均年龄的患者在数值上有更大的改善；60岁和接受≥20次干预的患者，但亚组间差异无统计学意义。结论vrbr是治疗PSD的有效方法。然而，需要方法学上严格的研究来进一步证实其有效性和安全性。试验注册号prospero， CRD42024550019。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Impact of virtual reality-based rehabilitation on poststroke depression: A systematic review and meta-analysis

Background

Depression is the most common neuropsychiatric sequela of stroke, negatively affecting functional recovery and quality of life. Although virtual reality-based rehabilitation (VRBR) is an effective intervention in stroke rehabilitation, its efficacy in treating poststroke depression (PSD) remains unclear.

Objectives

To evaluate the treatment effect of VRBR on PSD.

Data sources and methods

Six medical databases were systematically searched from inception to May 31, 2024, with an update on October 5, 2024. Potentially eligible studies were screened against the inclusion and exclusion criteria. Review Manager 5.4 and Stata 14.0 were used to conduct statistical analysis.

Results

Twelve studies published between 2015 and 2024 were included. The pooled results revealed that VRBR significantly reduced depression scores among poststroke patients [SMD = −0.56, 95 % CI (−0.90, −0.23), P = 0.001]. Subgroup analyses suggested numerically greater improvements in patients with a mean age < 60 years and those receiving ≥20 intervention sessions, though between-subgroup differences were not statistically significant.

Conclusion

VRBR may be a promising therapy for PSD. However, methodologically rigorous studies are needed to further confirm its efficacy and safety.

Trial registration

PROSPERO, CRD42024550019.

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来源期刊

General hospital psychiatry 医学-精神病学

CiteScore

9.60

自引率

2.90%

发文量

125

审稿时长

20 days

期刊介绍： General Hospital Psychiatry explores the many linkages among psychiatry, medicine, and primary care. In emphasizing a biopsychosocial approach to illness and health, the journal provides a forum for professionals with clinical, academic, and research interests in psychiatry''s role in the mainstream of medicine.