{"title":"Establishment and clinical impacts of decision-support system for older patients with aortic valve stenosis: A retrospective observational study","authors":"Sayoko Kawano , Yoko Eguchi , Azusa Oosumi , Hiroyoshi Takeuchi , Michiyo Takubo , Noriko Kimura , Naomi Nakano , Toshinobu Ryuzaki , Kentaro Hayashida , Masaki Ieda , Hiroyuki Uchida , Masaru Mimura , Daisuke Fujisawa","doi":"10.1016/j.genhosppsych.2024.12.024","DOIUrl":"10.1016/j.genhosppsych.2024.12.024","url":null,"abstract":"<div><h3>Objectives</h3><div>Treatment decisions for severe aortic stenosis (AS) are complex, since there are two active and comparable options: transcatheter aortic valve implantation and surgical aortic valve replacement. The disease predominantly affects older individuals, who are frequently comorbid with from cognitive impairment. This study aimed to establish a screening-triggered system to assess the decision-making capacity of patients with AS, support their decision-making, and facilitate referrals to specialists when necessary.</div></div><div><h3>Methods</h3><div>This is a retrospective pre-post observational study. Relevant healthcare professionals were trained to assess and support patients' decision-making capacities.</div></div><div><h3>Results</h3><div>Subtotals of 203 and 244 patients were enrolled before and after the implementation of the system, respectively. The requests for decision-making support significantly increased (from 1.5 % to 14.8 % of the patients). 11.5 % of the patients were identified as with declined decision-making capacity. The proportion of patients who received active treatments for AS significantly decreased from 95.0 % to 83.0 %. The nurses' documentation of patients' decision-making capacities significantly increased.</div></div><div><h3>Conclusion</h3><div>This screening-triggered system identified a substantial proportion of patients with declined decision-making capacity. A significant decrease in patients receiving active treatments for AS and increased documentation of patients' decision-making capacities in nursing records were observed. A future randomized controlled is warranted.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 106-111"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina M. van der Feltz-Cornelis , Fidan Turk , Jennifer Sweetman , Kamlesh Khunti , Mark Gabbay , Jessie Shepherd , Hugh Montgomery , W. David Strain , Gregory Y.H. Lip , Dan Wootton , Caroline Leigh Watkins , Daniel J. Cuthbertson , Nefyn Williams , Amitava Banerjee
{"title":"Corrigendum to “Prevalence of mental health conditions and brain fog in people with long COVID: A systematic review and meta-analysis” [General Hospital Psychiatry volume 88 (2024)10–22 10.1016/j.genhosppsych.2024.02.009]","authors":"Christina M. van der Feltz-Cornelis , Fidan Turk , Jennifer Sweetman , Kamlesh Khunti , Mark Gabbay , Jessie Shepherd , Hugh Montgomery , W. David Strain , Gregory Y.H. Lip , Dan Wootton , Caroline Leigh Watkins , Daniel J. Cuthbertson , Nefyn Williams , Amitava Banerjee","doi":"10.1016/j.genhosppsych.2024.09.006","DOIUrl":"10.1016/j.genhosppsych.2024.09.006","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Page 112"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142283604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk of agranulocytosis and neutropenia in patients with Parkinson's disease psychosis receiving clozapine treatment: A systematic review and meta-analysis","authors":"Nahathai Limveeraprajak , Worawut Makkapavee , Surinporn Likhitsathian , Manit Srisurapanont","doi":"10.1016/j.genhosppsych.2024.12.003","DOIUrl":"10.1016/j.genhosppsych.2024.12.003","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the cumulative incidence of severe neutropenia and agranulocytosis (SNA) and mild and moderate neutropenia (MMN) in patients with Parkinson's disease psychosis (PDP) who receive clozapine treatment.</div></div><div><h3>Methods</h3><div>We searched multiple databases to identify clozapine studies in PDP patients. Incidence rates were assessed during short-term (within 1 month), medium-term (within 6 months), and long-term (> 6 months) monitoring periods. A proportional meta-analysis was performed using random-effects and generalized linear mixed models (GLMMs).</div></div><div><h3>Results</h3><div>We included 691 PDP patients from 19 studies. During the short-term monitoring period, none of the 573 participants in 16 studies developed SNA. The pooled incidence of SNA was 0.001 (95 % confidence interval [CI]: 0.000–0.253, 525 participants, 15 studies) during the medium-term period and 0.002 (95 % CI: 0.000–0.015, 475 participants, 12 studies) during the long-term period. The pooled incidence of MMN was 0.004 (95 % CI: 0.000–0.281, 164 participants, 7 studies) for short- and medium-term periods and 0.013 (95 % CI: 0.002–0.094, 193 participants, 7 studies) in the long-term period. Funnel plot asymmetry indicated potential bias in the medium-term dataset of SNA (<em>p</em> = 0.035).</div></div><div><h3>Conclusion</h3><div>Clozapine treatment in PDP patients may carry a very low risk of SNA and a low risk of MMN.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 4-11"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Home-Based Transcranial Direct Current Stimulation for Major Depressive Disorder: A Meta-Analysis of Randomized Controlled Trials","authors":"Omar Kassar , Moaz Elsayed Abouelmagd , Ahmed Elshahat , Sheikh Shoib","doi":"10.1016/j.genhosppsych.2024.12.015","DOIUrl":"10.1016/j.genhosppsych.2024.12.015","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 48-49"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142893806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of reversible visual impairments and their association with the psychiatric illness severity among inpatients with psychotic disorders","authors":"Mathieu Fradet , Fannie Nadeau , Alexandre Suey , Mazen Choulakian , Sylvain Grignon","doi":"10.1016/j.genhosppsych.2024.11.005","DOIUrl":"10.1016/j.genhosppsych.2024.11.005","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 135-136"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142618304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sharon Taub , Noa Menkes-Caspi , Tom Fruchtman-Steinbok , Shiri Kamhi-Nesher , Amir Krivoy
{"title":"Patients with severe mental illness in the general emergency department: Clinical characteristics, quality of care and challenges","authors":"Sharon Taub , Noa Menkes-Caspi , Tom Fruchtman-Steinbok , Shiri Kamhi-Nesher , Amir Krivoy","doi":"10.1016/j.genhosppsych.2024.11.014","DOIUrl":"10.1016/j.genhosppsych.2024.11.014","url":null,"abstract":"<div><h3>Background</h3><div>Morbidity and mortality rates are notably higher among individuals with severe mental illnesses (SMI). People with SMI often have lower access to healthcare services, and the medical care they receive is known to be suboptimal. Consequently, treatment in an acute care setting rather than a community setting is more common. We aim to explore medical care in the emergency department (ED) for people with SMI compared to a control population.</div></div><div><h3>Methods</h3><div>In this matched cohort study, data on all adult Clalit Health Services (CHS) members who were referred to the general ED during the years 2018–2021 were extracted. Patients with SMI (ICD-10 codes for schizophrenia, schizoaffective disorder, and bipolar disorder) were matched with a control group of ED patients without SMI in a 1:3 ratio. The two groups were compared regarding ED admission reasons, management, and outcomes.</div></div><div><h3>Results</h3><div>The total sample (<em>n</em> = 92,848) included ED patients with SMI (<em>n</em> = 23,212) and without (<em>n</em> = 69,636). The most common ED admission reasons in both groups were pain, traumatic injury, and cardiac symptoms. Patients in the SMI group had higher rates of diagnosed diabetes mellitus and obstructive pulmonary disease.</div><div>ED assessment, measured by resource allocation, was less comprehensive for patients with SMI who presented with subjective complaints such as pain and weakness, while it was comparable between patients with and without SMI for other main presenting complaints. Workup for patients with SMI lasted longer and necessitated hospitalization at higher rates for most admission reasons. Mortality during the study period was almost twice as high among the SMI group (5 % vs. 2.3 %, <em>p</em> < 0.001).</div></div><div><h3>Discussion</h3><div>Our findings indicate higher rates of morbidity and treatment complexity among patients with SMI. As expected, the mortality rate was higher in this group. An alarming gap in resource allocation for ED assessment was observed when patients presented with subjective complaints. Enhanced awareness and integrated resources in primary care are required to improve the management and physical healthcare of patients with SMI.</div></div>","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 100-105"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: “Global prevalence of poor sleep quality in cancer patients: A systematic review and meta-analysis”","authors":"Jingjing Hu, Shuangqin Chen","doi":"10.1016/j.genhosppsych.2024.11.001","DOIUrl":"10.1016/j.genhosppsych.2024.11.001","url":null,"abstract":"","PeriodicalId":12517,"journal":{"name":"General hospital psychiatry","volume":"92 ","pages":"Pages 131-132"},"PeriodicalIF":4.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}