中国老年人认知衰弱的患病率：系统回顾和荟萃分析

IF 4.1 2区医学 Q1 PSYCHIATRY

General hospital psychiatry Pub Date : 2025-07-10 DOI:10.1016/j.genhosppsych.2025.07.008

Ziyu Wang , Lu Lin , Shufang Zuo , Cui Ye , Xuan Huang , Yong Xu

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引用次数: 0

摘要

背景与目的随着中国人口的老龄化，认知衰弱（CF）的患病率正在上升，带来了生活质量下降、住院率和死亡率上升、认知功能障碍和痴呆等重大风险。本研究旨在通过系统回顾和荟萃分析来确定中国老年人CF的患病率，为卫生保健政策和实践提供证据。方法系统检索PubMed、Web of Science、Embase、Cochrane Library、中国知网（CNKI）、万方网（WanFang）、维普网（VIP）、中国医学信息网（SinoMed）等8个数据库自其成立至2024年4月5日的数据。包括观察性研究（横断面、队列或基于人群的纵向研究）。两名研究人员独立审查了文献，提取了数据，并评估了研究的质量。所有统计分析均使用Stata 14.2进行。结果共筛选到79,059条记录，其中93项研究涉及89760名中国老年人符合纳入标准。合并CF患病率确定为21% (95% CI: 0.19, 0.23, P <；0.001)。值得注意的是，CF患病率在各个亚组之间差异显著，这取决于年龄、性别、教育程度、婚姻状况、生活安排、是否存在高血压、是否存在糖尿病、BMI、跌倒史、营养状况、睡眠状况、运动、日常生活活动、多种药物和是否存在抑郁症状等变量(所有P <；0.001)。本研究显示，中国老年人CF的总患病率为21%，并且从2012年到2023年有上升趋势。CF患病率受人口统计学、健康和生活方式因素的影响。这些发现强调了CF的复杂性，并强调需要确定关键的风险和保护因素，以及制定针对这一人群的健康和生活方式因素的有针对性的干预措施。

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Prevalence of cognitive frailty among Chinese older adults: A systematic review and meta-analysis

Background and purpose

With China's aging population, the prevalence of cognitive frailty (CF) is increasing, posing significant risks such as reduced quality of life, higher hospitalization and mortality rates, cognitive impairment, and dementia. This study aimed to determine the prevalence of CF among Chinese older adults through a systematic review and meta-analysis to provide evidence that informs healthcare policy and practice.

Methods

A systematic search was conducted across eight databases: PubMed, Web of Science, Embase, the Cochrane Library, CNKI, WanFang, VIP, and SinoMed from their inception up to April 5, 2024. Observational studies (cross-sectional, cohort, or population-based longitudinal studies) were included. Two researchers independently reviewed the literature, extracted data, and assessed the quality of the studies. All statistical analyses were performed using Stata 14.2.

Results

A total of 79,059 records were screened, of which 93 studies involving 89,760 Chinese older adults met the inclusion criteria. The pooled CF prevalence was determined to be 21 % (95 % CI: 0.19, 0.23, P < 0.001). Notably, CF prevalence varied significantly across subgroups, depending on variables such as age, gender, education, marital status, living arrangements, presence of hypertension, presence of diabetes, BMI, history of falls, nutritional status, sleep condition, exercise, activities of daily living, polypharmacy, and presence of depressive symptoms (all P < 0.001).

Conclusions

This study revealed a pooled CF prevalence of 21 % among Chinese older adults, with a concerning upward trend from 2012 to 2023. The CF prevalence was influenced by demographic, health, and lifestyle factors. These findings underscore the complexity of CF and highlight the need to identify key risk and protective factors, as well as to develop targeted interventions that address both health and lifestyle factors in this population.

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来源期刊

General hospital psychiatry 医学-精神病学

CiteScore

9.60

自引率

2.90%

发文量

125

审稿时长

20 days

期刊介绍： General Hospital Psychiatry explores the many linkages among psychiatry, medicine, and primary care. In emphasizing a biopsychosocial approach to illness and health, the journal provides a forum for professionals with clinical, academic, and research interests in psychiatry''s role in the mainstream of medicine.