Frontiers in Nutrition最新文献

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Protein quality malnutrition. 蛋白质质量营养不良。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-23 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1428810
Mark J Manary, Donna R Wegner, Kenneth Maleta
{"title":"Protein quality malnutrition.","authors":"Mark J Manary, Donna R Wegner, Kenneth Maleta","doi":"10.3389/fnut.2024.1428810","DOIUrl":"10.3389/fnut.2024.1428810","url":null,"abstract":"<p><p>Protein quality refers to the evaluation of a food or a diet based on its amino acid composition, protein digestibility, and protein bioavailability. When these parameters are specified, either through direct measurement or estimation, the amino acids provided by the diet are compared to those required by a healthy individual, and based on this comparison, an adequacy ratio or score is assigned. Two widely used protein quality scoring systems are the protein digestibility-corrected amino acid score (PDCAAS) and the digestible indispensable amino acid score (DIAAS), neither of which account for the dietary source of the protein. In malnourished children, metabolic adaptations reduce the endogenous availability of amino acids and increase the demand for protein synthesis. These increased amino acid requirements are primarily driven by the presence of acute infection and the need for tissue accretion. This review examines two large clinical feeding trials involving moderately malnourished children, where dietary protein quality was carefully measured. The finding s suggest that protein quality scores alone do not reliably predict weight gain or recovery in these children and that consuming milk protein provides distinct advantages over vegetable-based proteins.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1428810"},"PeriodicalIF":4.0,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11537847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011-2018 data. 美国成年女性饮茶与中风之间的关系:NHANES 2011-2018 年数据分析。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1452137
Yongyue Miao, Sijia Ma, Xian Wu
{"title":"Association between tea consumption and stroke in the American adult females: analyses of NHANES 2011-2018 data.","authors":"Yongyue Miao, Sijia Ma, Xian Wu","doi":"10.3389/fnut.2024.1452137","DOIUrl":"10.3389/fnut.2024.1452137","url":null,"abstract":"<p><strong>Background: </strong>Epidemiological surveys show that there is a significant gender difference in the incidence of stroke, with females having a noticeably higher rate than males. Accordingly, it is crucial to seek preventive measures for stroke specifically targeted at females. Although previous studies have shown that tea has been proven to be negatively correlated with stroke, the relationship between tea and stroke in American adult females is still unclear. Therefore, we aimed to investigate the relationship between tea consumption and the occurrence of stroke in American adult females.</p><p><strong>Methods: </strong>The data analyzed is derived from the NHANES database between 2011 and 2018. The quantity of tea consumed was gathered from a 24-h dietary review. Stroke was identified by using questionnaire. The association between tea consumption and stroke was investigated using a weighted regression model. Then we used interaction testing and subgroup analysis to conduct a thorough analysis. Simultaneously, the association between the sugar content in tea and stroke was examined.</p><p><strong>Results: </strong>This study included 5731 adult females aged between 20 and 60 years. Compared to those who did not consume tea, the likelihood of stroke decreased by 9% for each additional 100 g of tea ingested by participants (OR = 0.91, 95%CI: 0.83-1.00). In the unadjusted model, those who drank 307.5-480 g of tea per day had a substantially decreased risk of stroke than those who did not drink tea (OR = 0.23, 95%CI: 0.08-0.64). After adjustment, this relationship also persisted (Model II: OR = 0.23, 95% CI: 0.08-0.64; Model III: OR = 0.23, 95% CI: 0.08-0.66). In both Model II and Model III, there was a statistically significant relationship between consuming 480-744 g of tea per day and the risk of stroke (Model II: OR = 0.39, 95%CI: 0.16-0.94; Model III: OR = 0.42, 95% CI: 0.18-0.98). Subgroup analysis revealed an interaction only with level of education (<i>P</i> = 0.031). Ultimately, we also demonstrated that people who drink sugar free tea have a lower risk of stroke, and even after adjusting for mixed factors.</p><p><strong>Conclusion: </strong>This study suggested that proper tea consumption was associated with a lower risk of stroke in adult females, which recommended drinking sugar free tea.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1452137"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Anti-inflammatory diet in autoimmune diseases. 社论:自身免疫性疾病中的抗炎饮食。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1497058
Ifigenia Kostoglou-Athanassiou, Panagiotis Athanassiou
{"title":"Editorial: Anti-inflammatory diet in autoimmune diseases.","authors":"Ifigenia Kostoglou-Athanassiou, Panagiotis Athanassiou","doi":"10.3389/fnut.2024.1497058","DOIUrl":"10.3389/fnut.2024.1497058","url":null,"abstract":"","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1497058"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation of gut microbiome in response to the combination of Escherichia coli Nissle 1917 and sugars: a pilot study using host-free system reflecting impact on interpersonal microbiome. 大肠杆菌 Nissle 1917 与糖的结合对肠道微生物群的调节:一项使用无宿主系统的试验研究,反映了对人际微生物群的影响。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1452784
Kiran Heer, Manpreet Kaur, Dwinder Sidhu, Priyankar Dey, Saumya Raychaudhuri
{"title":"Modulation of gut microbiome in response to the combination of <i>Escherichia coli</i> Nissle 1917 and sugars: a pilot study using host-free system reflecting impact on interpersonal microbiome.","authors":"Kiran Heer, Manpreet Kaur, Dwinder Sidhu, Priyankar Dey, Saumya Raychaudhuri","doi":"10.3389/fnut.2024.1452784","DOIUrl":"10.3389/fnut.2024.1452784","url":null,"abstract":"<p><strong>Introduction: </strong>The differential effects of probiotic, prebiotic, and synbiotic formulations on human health are dictated by the inter-individual gut microbial profile. The effects of probiotics such as <i>Escherichia coli</i> Nissle 1917 (ECN) on gut microbiota may vary according to the microbiome profiles of individuals and may be influenced by the presence of certain carbohydrates, which can impact microbial community structure and treatment results.</p><p><strong>Method: </strong>Processed fecal samples from donors having contrasting lifestyles, dietary patterns, and disease histories were mixed with 5 × 10<sup>6</sup> CFU/mL ECN with or without 1% (w/v) sugars (glucose, galactose, or rice starch) in a host-free system. Post-incubation, 16 s rRNA sequencing was performed. Microbial diversity and taxonomic abundance were computed in relation to the probiotic, prebiotic, and synbiotic treatment effects and interpersonal microbiome variance.</p><p><strong>Result: </strong>Baseline gut microbial profiles showed significant inter-individual variations. ECN treatment alone had a limited impact on the inter-personal gut microbial diversity and abundance. Prebiotics caused a substantial enrichment in Actinobacteria, but there were differences in the responses at the order and genus levels, with enrichment shown in <i>Bifidobacterium</i>, <i>Collinsella</i>, and <i>Megasphaera</i>. Subject B exhibited enrichment in Proteobacteria and Cyanobacteria, but subject A showed more diversified taxonomic alterations as a consequence of the synbiotic treatments. Despite negligible difference in the <i>α</i>-diversity, probiotic, prebiotic, and synbiotic treatments independently resulted in distinct segregation in microbial communities at the <i>β</i>-diversity level. The core microbiota was altered only under prebiotic and synbiotic treatment. Significant correlations primarily for minor phyla were identified under prebiotic and synbiotic treatment.</p><p><strong>Conclusion: </strong>The interindividual microbiome composition strongly influences the effectiveness of personalized diet and treatment plans. The responsiveness to dietary strategies varies according to individual microbiome profiles influenced by health, diet, and lifestyle. Therefore, tailored approaches that consider individual microbiome compositions are crucial for maximizing gut health and treatment results.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1452784"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and evaluation of a web-based diet quality screener for vegans (VEGANScreener): a cross-sectional, observational, multicenter, clinical study. 开发和评估基于网络的素食者饮食质量筛选器(VEGANScreener):一项横断面、观察性、多中心临床研究。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1438740
Tooba Asif, Anna Ouřadová, Ainara Martínez Tabar, Vanessa Bullón-Vela, Sandra Müller, Joelina Dietrich, Vanessa Keller, Marina Heniková, Eliška Selinger, Isabelle Herter-Aeberli, Maria Wakolbinger, Willem De Keyzer, Wendy Van Lippevelde, Monika Cahová, Leonie H Bogl, Marek Kuzma, Maira Bes-Rastrollo, Stefaan De Henauw, Markus Keller, Selma Kronsteiner-Gicevic, Eva Schernhammer, Jan Gojda
{"title":"Development and evaluation of a web-based diet quality screener for vegans (VEGANScreener): a cross-sectional, observational, multicenter, clinical study.","authors":"Tooba Asif, Anna Ouřadová, Ainara Martínez Tabar, Vanessa Bullón-Vela, Sandra Müller, Joelina Dietrich, Vanessa Keller, Marina Heniková, Eliška Selinger, Isabelle Herter-Aeberli, Maria Wakolbinger, Willem De Keyzer, Wendy Van Lippevelde, Monika Cahová, Leonie H Bogl, Marek Kuzma, Maira Bes-Rastrollo, Stefaan De Henauw, Markus Keller, Selma Kronsteiner-Gicevic, Eva Schernhammer, Jan Gojda","doi":"10.3389/fnut.2024.1438740","DOIUrl":"10.3389/fnut.2024.1438740","url":null,"abstract":"<p><p>Consumption of plant-based diets, including vegan diets, necessitates attention to the quality of the diet for the prevention and early detection of nutritional deficiencies. Within the VEGANScreener project, a unique brief screening tool for the assessment and monitoring of diet quality among vegans in Europe was developed. To provide a standardized tool for public use, a clinical study will be conducted to evaluate the VEGANScreener against a reference dietary assessment method and nutritional biomarkers. An observational study is set to include 600 participants across five European sites - Belgium, Czech Republic, Germany, Spain, and Switzerland. In total, 400 self-reported vegans (≥2 years on a vegan diet), and 170 self-reported omnivore controls will be examined, aged between 18 and 65 years, with males and females being equally represented in a 1:1 ratio for two age groups (18-35 and 36-65 years). Participants with diseases affecting metabolism and intestinal integrity will be excluded. The clinical assessment will include a structured medical history, along with taking blood pressure and anthropometric measurements. Blood and urine will be sampled and analyzed for a set of dietary biomarkers. Metabolomic analyses will be conducted to explore potential novel biomarkers of vegan diet. Moreover, saliva samples will be collected to assess the metabolome and the microbiome. Participants will receive instructions to complete a nonconsecutive 4-day diet record, along with the VEGANScreener, a socio-demographic survey, a well-being survey, and a FFQ. To evaluate reproducibility, the VEGANScreener will be administered twice over a three-weeks period. Among vegans, the construct validity and criterion validity of the VEGANScreener will be analyzed through associations of the score with nutrient and food group intakes, diet quality scores assessed from the 4-day diet records, and associations with the dietary biomarkers. Secondary outcomes will include analysis of dietary data, metabolomics, and microbiomes in all participants. Major nutrient sources and variations will be assessed in the sample. Exploratory metabolomic analysis will be performed using multivariable statistics and regression analysis to identify novel biomarkers. Standard statistical models will be implemented for cross-sectional comparisons of geographical groups and vegans versus omnivores.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1438740"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of nitrogen and phosphorus application on starch characteristics and quality of rice with different nitrogen efficiency. 施氮和施磷对不同氮效率水稻淀粉特性和品质的影响
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1462689
Guotao Yang, Qin Wang, Guohao Zhang, Chunyan Jiang, Peng Ma, Yungao Hu
{"title":"Effect of nitrogen and phosphorus application on starch characteristics and quality of rice with different nitrogen efficiency.","authors":"Guotao Yang, Qin Wang, Guohao Zhang, Chunyan Jiang, Peng Ma, Yungao Hu","doi":"10.3389/fnut.2024.1462689","DOIUrl":"10.3389/fnut.2024.1462689","url":null,"abstract":"<p><strong>Introduction: </strong>The application of nitrogen and phosphorus fertilizers is an important factors affecting the quality of rice, and different nitrogen-efficient rice varieties show significant differences in their response to nitrogen and phosphorus application.</p><p><strong>Methods: </strong>In this experiment, a low-nitrogen-high efficiency variety (Deyou 4727) and a high-nitrogen-high efficiency variety (Jingyou 781) were selected, and the changes in rice quality and differences in starch structure under nitrogen-phosphorus interaction treatments were determined.</p><p><strong>Results: </strong>Appearance, flavor, starch content and thermodynamic properties, endosperm cell arrangement, and starch granule morphology and size were significantly influenced by variety, nitrogen-phosphorus interactions, and their interaction effects. The effect of nitrogen fertilizer on quality was greater than that of phosphorus fertilizer. The whiteness and chalkiness rates of Deyou 4727 first decreased and then increased with increasing nitrogen fertilizer application, wheras the appearance quality of Jingyou 781 increased with increasing nitrogen fertilizer application. Starch crystallinity in Deyou 4727 first increased and then decreased with increasing nitrogen fertilizer application, whereas starch crystallinity in Jingyou 781 increased continuously with increasing nitrogen fertilizer application. The application of phosphorus fertilizer led to an increase in starch crystallinity in both nitrogen-efficient rice varieties, consistent with the response of different rice varieties to nitrogen and phosphorus in terms of appearance and chalkiness. With the increasing application of nitrogen and phosphorus fertilizers, the differences in the physicochemical properties and structure of starch became more significant.</p><p><strong>Discussion: </strong>High-nitrogen-efficient rice varieties can significantly improve appearance quality under high nitrogen conditions, and the interactions of medium-high nitrogen and low-medium phosphorus can lead to a significant decrease in starch thermal parameters and retention rate, thus improving rice cooking quality. Low-nitrogen-efficient rice varieties can also improve the quality of rice under low-medium-nitrogen conditions with appropriate application of phosphorus fertilizer.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1462689"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and validation of a novel prognostic prediction system based on GLIM-defined malnutrition for colorectal cancer patients post-radical surgery. 基于 GLIM 定义的结直肠癌患者根治术后营养不良的新型预后预测系统的开发与验证。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1425317
Xialin Yan, Junchang Zhu, Junqi Wang, Yingjie Lu, Xingzhao Ye, Xiangwei Sun, Haojie Jiang, Zongze Li, Chenhao He, Wenbo Zhai, Qiantong Dong, Weizhe Chen, Zhen Yu, Yifei Pan, Dongdong Huang
{"title":"Development and validation of a novel prognostic prediction system based on GLIM-defined malnutrition for colorectal cancer patients post-radical surgery.","authors":"Xialin Yan, Junchang Zhu, Junqi Wang, Yingjie Lu, Xingzhao Ye, Xiangwei Sun, Haojie Jiang, Zongze Li, Chenhao He, Wenbo Zhai, Qiantong Dong, Weizhe Chen, Zhen Yu, Yifei Pan, Dongdong Huang","doi":"10.3389/fnut.2024.1425317","DOIUrl":"10.3389/fnut.2024.1425317","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition often occurs in patients with colorectal cancer. This study aims to develop a predictive model based on GLIM criteria for patients with colorectal cancer who underwent radical surgery.</p><p><strong>Methods: </strong>From December 2015 to May 2021, patients with colorectal cancer who underwent radical surgery at our center were recruited for this study. We prospectively collected data on GLIM-defined malnutrition and other clinicopathological characteristics. Using Cox regeneration, we developed a novel nomogram for prognostic prediction, which was validated and compared to traditional nutritional factors for predictive accuracy.</p><p><strong>Results: </strong>Among the 983 patients enrolled in this study, malnutrition was identified in 233 (23.70%) patients. Multivariate analysis indicated that GLIM-defined malnutrition is the independent risk factor for overall survival (HR = 1.793, 95% CI = 1.390-2.313 for moderate malnutrition and HR = 3.485, 95% CI = 2.087-5.818 for severe malnutrition). The novel nomogram based on the GLIM criteria demonstrated a better performance than existing criteria, with AUC of 0.729, 0.703, and 0.683 for 1-year, 3-year, and 5-year OS, respectively, in the validation cohort. In addition, the risk score determined by this system exhibited significantly poorer short-term and long-term clinical outcomes in high-risk groups in both malnourished and well-nourished patients.</p><p><strong>Conclusion: </strong>Combining handgrip strength, serum albumin level, and TNM stage would help improve the predictive effect of GLIM criteria for colorectal cancer patients post-radical surgery and benefit the individual prognostic prediction of colorectal cancer.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1425317"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reinventing gut health: leveraging dietary bioactive compounds for the prevention and treatment of diseases. 重塑肠道健康:利用膳食生物活性化合物预防和治疗疾病。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1491821
Qiurong Wang, Hui Huang, Ying Yang, Xianglan Yang, Xuemei Li, Wei Zhong, Biao Wen, Feng He, Jun Li
{"title":"Reinventing gut health: leveraging dietary bioactive compounds for the prevention and treatment of diseases.","authors":"Qiurong Wang, Hui Huang, Ying Yang, Xianglan Yang, Xuemei Li, Wei Zhong, Biao Wen, Feng He, Jun Li","doi":"10.3389/fnut.2024.1491821","DOIUrl":"10.3389/fnut.2024.1491821","url":null,"abstract":"<p><p>The human gut harbors a complex and diverse microbiota essential for maintaining health. Diet is the most significant modifiable factor influencing gut microbiota composition and function, particularly through bioactive compounds like polyphenols, dietary fibers, and carotenoids found in vegetables, fruits, seafood, coffee, and green tea. These compounds regulate the gut microbiota by promoting beneficial bacteria and suppressing harmful ones, leading to the production of key microbiota-derived metabolites such as short-chain fatty acids, bile acid derivatives, and tryptophan metabolites. These metabolites are crucial for gut homeostasis, influencing gut barrier function, immune responses, energy metabolism, anti-inflammatory processes, lipid digestion, and modulation of gut inflammation. This review outlines the regulatory impact of typical bioactive compounds on the gut microbiota and explores the connection between specific microbiota-derived metabolites and overall health. We discuss how dietary interventions can affect disease development and progression through mechanisms involving these metabolites. We examine the roles of bioactive compounds and their metabolites in the prevention and treatment of diseases including inflammatory bowel disease, colorectal cancer, cardiovascular diseases, obesity, and type 2 diabetes mellitus. This study provides new insights into disease prevention and underscores the potential of dietary modulation of the gut microbiota as a strategy for improving health.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1491821"},"PeriodicalIF":4.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11534667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Higher protein intake may benefit in patients with prolonged mechanical ventilation. 长期机械通气患者摄入较多蛋白质可能会有好处。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1449240
Chiung-Hsin Chang, Chun-Yu Lin, Yu-Lun Lo, Ting-Yu Lin, Chen-Yiu Hung, Meng-Heng Hsieh, Yueh-Fu Fang, Hung-Yu Huang, Shu-Min Lin, Horng-Chyuan Lin
{"title":"Higher protein intake may benefit in patients with prolonged mechanical ventilation.","authors":"Chiung-Hsin Chang, Chun-Yu Lin, Yu-Lun Lo, Ting-Yu Lin, Chen-Yiu Hung, Meng-Heng Hsieh, Yueh-Fu Fang, Hung-Yu Huang, Shu-Min Lin, Horng-Chyuan Lin","doi":"10.3389/fnut.2024.1449240","DOIUrl":"10.3389/fnut.2024.1449240","url":null,"abstract":"<p><strong>Background: </strong>Patients with prolonged mechanical ventilation (PMV) is usually associated with muscle wasting and diaphragm weakness, resulting in high medical costs and mortality. Adequate energy and protein intake were beneficial in sarcopenia patients. We aimed to investigate the impact of protein intake in weaning parameters in patients with PMV.</p><p><strong>Materials and methods: </strong>We enrolled patients with PMV (mechanical ventilation ≥6 h/day for ≥21 days) from a respiratory care center (RCC) of a tertiary medical center from December 2020 to October 2022, and classified them into weaning success and weaning failure groups. The patients' characteristics, nutrition records, weaning parameters and outcomes were analyzed.</p><p><strong>Results: </strong>A total of 289 patients were included (mean age 73.5 years). Of the 289 patients, 149 were weaned successfully and 140 were not. The average protein intake was higher in the weaning success group than in the weaning failure group (1.22 ± 0.320 versus 0.99 ± 0.332 g/kg/day, <i>p</i> < 0.001). No significant differences were noted in the average calorie intake and whey protein intake between the two groups. RSBI <90 breaths/min/L (OR = 2.38, <i>p</i> = 0.045), serum albumin at 4th week ≥3 g/dL (OR = 2.89, <i>p</i> = 0.027), daily protein intake ≥1.01 g/kg/day (OR = 8.10, <i>p</i> < 0.001), PaO<sub>2</sub>/FiO<sub>2</sub> (PF) ratio ≥ 300 (OR = 2.56, <i>p</i> = 0.027) were independent predictors for weaning from ventilator. Weak positive correlations were found between average protein intake with PF ratio (<i>r</i> = 0.1576, <i>p</i> = 0.0227) and PaO<sub>2</sub> (<i>r</i> = 0.13359, <i>p</i> = 0.0497).</p><p><strong>Conclusion: </strong>Daily protein intake had positively correlated with PF ratio and had independently benefit for weaning in patients with PMV.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1449240"},"PeriodicalIF":4.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11533934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum: Validity and agreement between dual-energy X-ray absorptiometry, anthropometry and bioelectrical impedance in the estimation of fat mass in young adults. 更正:双能 X 射线吸收测定法、人体测量法和生物电阻抗法在估算青壮年脂肪量方面的有效性和一致性。
IF 4 2区 农林科学
Frontiers in Nutrition Pub Date : 2024-10-21 eCollection Date: 2024-01-01 DOI: 10.3389/fnut.2024.1488063
Malek Mecherques-Carini, Mario Albaladejo-Saura, Raquel Vaquero-Cristóbal, Nicolás Baglietto, Francisco Esparza-Ros
{"title":"Corrigendum: Validity and agreement between dual-energy X-ray absorptiometry, anthropometry and bioelectrical impedance in the estimation of fat mass in young adults.","authors":"Malek Mecherques-Carini, Mario Albaladejo-Saura, Raquel Vaquero-Cristóbal, Nicolás Baglietto, Francisco Esparza-Ros","doi":"10.3389/fnut.2024.1488063","DOIUrl":"https://doi.org/10.3389/fnut.2024.1488063","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fnut.2024.1421950.].</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1488063"},"PeriodicalIF":4.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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