Frontiers in Nutrition最新文献

{"title":"Nutrition-sensitive agricultural interventions and maternal and child nutrition outcomes in arid and semi-arid lands of Kenya.","authors":"Frederick K E Grant, Dorcas Amunga, Chalmers K Mulwa, Mukani Moyo, Norman Kwikiriza, Jack Malit, Lucy Mwaura, Joyce Maru, Simon Heck","doi":"10.3389/fnut.2025.1465650","DOIUrl":"https://doi.org/10.3389/fnut.2025.1465650","url":null,"abstract":"<p><strong>Background: </strong>In regions facing chronic stress such as the arid and semi-arid lands (ASALs) of Kenya, there is poor quality of diet among women and children in humanitarian situations, mainly due to multiple climatic shocks that exacerbate local food systems. The objective of this study was to assess the effect of household participation in climate smart nutrition-sensitive agriculture (NSA) interventions on maternal and young child nutrition outcomes in Makueni, Garissa and Tana River counties.</p><p><strong>Methods: </strong>From March 2020 to October 2023, the International Potato Center and partners (World Food Program, Ministries of Agriculture and Health) implemented an NSA intervention in Makueni, Garissa and Tana River counties. The intervention comprised of household participating in three main activities: (1) access to orange fleshed sweetpotato (OFSP) vines; (2) participation in nutrition education activities and (3) receiving and utilizing infant feeding toolkits (Healthy Baby Toolkit/HBT). Approximately 3 months after intervention activities, we conducted a cross-sectional survey in intervention communities to assess effect of particpation in the interventions on maternal and child nutrition outcomes. The study utilized the doubly robust <i>inverse probability weighting regression adjustment</i> (IPWRA) estimator to evaluate the impact of participation in the project intervention on nutrition outcomes. Caregivers' knowledge of nutrition, health and childcare, women (MDD-W) and young child dietary diversity (MDD-C), vitamin A (VA) intakes, minimum meal frequency (MMF), and minimum acceptable diet (MAD) for children 6-23 months were analyzed. The comparison of means and proportions was assessed using Student's t-test and the Chi-square test, respectively, between the caregivers participating in NSA interventions and non-participants. The impact of the level of participation in NSA interventions and information on how to utilize these to improve infant and maternal feeding in the household on caregiver knowledge and practices scores was examined using regression analysis.</p><p><strong>Results: </strong>Of 494 caregivers surveyed, 72% indicated to have participated in at least one study intervention. In adjusted analyses, participation in at least one of the study interventions was significantly associated with improved caregiver nutrition [<i>β</i>: 0.943, <i>p</i> < 0.05], and VA [0.613, <i>p</i> < 0.05] knowledge scores and young child MMF [0.202, <i>p</i> < 0.05] and MAD [0.111, <i>p</i> < 0.05]. Participation in all three interventions (nutrition training, use of infant feeding toolkit and access to OFSP vines) significantly increased VA knowledge among caregivers (<i>p</i> ≤ 0.05) and infant MMF (<i>p</i> ≤ 0.05). While the use of infant feeding toolkit and access to OFSP vines alone had a significant positive effect on MDD-W and MDD-C (<i>p</i> ≤ 0.05).</p><p><strong>Conclusion: </strong>The findings show the ne","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1465650"},"PeriodicalIF":4.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical and agro-morphological traits-based mining for Malt Barley Germplasm.","authors":"Shakti Khera, Prakash Kumar, Shashi Bhushan Tripathi, Sherry Racheal Jacob, Dinesh Kumar, Charan Singh, Rakesh Bhardwaj, Sudhir Pal Ahlawat, Jai Chand Rana, Amritbir Riar","doi":"10.3389/fnut.2025.1480708","DOIUrl":"https://doi.org/10.3389/fnut.2025.1480708","url":null,"abstract":"<p><p>Barley serves as a crucial feed crop and is also utilized for baking, malting, and brewing purposes. In India, the consistent demand for malting-type barley has not been met due to the lack of suitable varieties. This study evaluated 136 barley germplasm accessions for diversity in biochemical and agro-morphological traits. The accessions were grown in Augmented Block Design and biochemical estimations were carried out using official and standard methods. The accessions exhibited substantial biochemical diversity with protein content (PC) ranging from 8.6 to 17.4%, starch content (SC) from 32.4 to 60.3%, amylose content (AC) from 13.3 to 19.3%, <i>β</i>-glucan content (βgC) from 1.31 to 6.06%, and total phenol content (TPC) from 8.6 to 17.4%. The agro-morphological traits also displayed considerable variation, with days to spike emergence (DSE) ranging from 74 to 124 days, days to physiological maturity (DPM) from 119 to 147 days, plant height (PH) from 82 to 165 cm, spike length (SL) from 5 to 11 cm, spikelet triplet groups (STG) per spike from 13 to 35, grain number per spike (GNS) from 15 to 71, hundred-grain weight (HGW) from 2 to 6.7 grams, and grain yield per meter row (GY) from 13.7 to 236.3 grams. Multivariate analyses, including the Mantel test, Pearson's correlation, principal component analysis (PCA), and hierarchical cluster analysis (HCA), were conducted. No significant correlation was observed between biochemical and agro-morphological traits. However, significant positive correlations were found between SC and AC (<i>r</i> = 0.48) and βgC with PC (<i>r</i> = 0.2). Significant negative correlations were observed between SC and PC (<i>r</i> = -0.41) and AC with PC (<i>r</i> = -0.4). Highly significant positive correlations were observed between DSE and DPM (<i>r</i> = 0.55), GY and PH (<i>r</i> = 0.29), PH and DPM (<i>r</i> = 0.2), and HGW and SL (<i>r</i> = 0.25). The GWL was significantly positively correlated with βgC (<i>r</i> = 0.257) and significantly negatively correlated with TPC (<i>r</i> = -0.235). Apart from Grain Width to Length Ratio (GWL), no other agro-morphological trait was significantly correlated with any biochemical trait. Various accessions suitable for malting, human food, and cattle feed applications were identified.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1480708"},"PeriodicalIF":4.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma: a clinical study.","authors":"Andreas Kiryttopoulos, Athanasios E Evangeliou, Irene Katsanika, Ioannis Boukovinas, Nikolaos Foroglou, Basilios Zountsas, Angeliki Cheva, Vaios Nikolopoulos, Thomas Zaramboukas, Tomas Duraj, Thomas N Seyfried, Martha Spilioti","doi":"10.3389/fnut.2024.1489812","DOIUrl":"https://doi.org/10.3389/fnut.2024.1489812","url":null,"abstract":"<p><strong>Introduction: </strong>Glioblastoma multiforme (GBM) ranks as one of the most aggressive primary malignant tumor affecting the brain. The persistent challenge of treatment failure and high relapse rates in GBM highlights the need for new treatment approaches. Recent research has pivoted toward exploring alternative therapeutic methods, such as the ketogenic diet, for GBM.</p><p><strong>Methods: </strong>A total of 18 patients with GBM, 8 women and 10 men, aged between 34 and 75 years participated in a prospective study, examining the impact of ketogenic diet on tumor progression. The pool of patients originated from our hospital during the period from January 2016 until July 2021 and were followed until January 2024. As an assessment criterion, we set an optimistic target for adherence to the ketogenic diet beyond 6 months. We considered the therapeutic combination successful if the survival reached at least 3 years.</p><p><strong>Results: </strong>Among the 18 patients participating in the study, 6 adhered to the ketogenic diet for more than 6 months. Of these patients, one patient passed away 43 months after diagnosis, achieving a survival of 3 years; another passed away at 36 months, narrowly missing the 3-year survival mark; and one is still alive at 33 months post-diagnosis but has yet to reach the 3-year milestone and is, therefore, not included in the final survival rate calculation. The remaining 3 are also still alive, completing 84,43 and 44 months of life, respectively. Consequently, the survival rate among these patients is 4 out of 6, or 66.7%. Of the 12 patients who did not adhere to the diet, only one reached 36 months of survival, while the rest have died in an average time of 15.7 ± 6.7 months, with a 3-year survival rate of 8.3%. Comparing the survival rates of the two groups, we see that the difference is 58.3% (66.7% versus 8.3%) and is statistically significant with <i>p</i> < 0.05 (0.0114) and X² = 6.409.</p><p><strong>Discussion: </strong>The outcomes observed in these patients offer promising insights into the potential benefits of the ketogenic diet on the progression of glioblastoma multiforme when compared to those who did not follow the diet consistently.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1489812"},"PeriodicalIF":4.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11876051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between constipation and the urine albumin-to-creatinine ratio in adults: the NHANES 2009-2010.","authors":"Yuying Yang, Siyi Rao, Yongjie Zhuo, Yuan Fang, Jianxin Wan, Danyu You","doi":"10.3389/fnut.2025.1477148","DOIUrl":"10.3389/fnut.2025.1477148","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the association between constipation and the urine albumin-to-creatinine ratio (ACR) using data from the National Health and Nutrition Examination Survey (NHANES) 2009-2010.</p><p><strong>Methods: </strong>In this cross-sectional study, a sample of 4,282 adults aged 20 and older was selected from the NHANES 2009-2010. Constipation was defined as having fewer than three bowel movements per week. The average of the two ACR measurements was used as the outcome variable. Logistic regression models (non-adjusted and multivariate adjusted models) were used to examine the relationship between constipation and ACR. Subgroup and interaction analyses related to gender, age, smoking, alcohol consumption, body mass index (BMI), hypertension, and diabetes were also conducted to assess the stability of the association between constipation and ACR.</p><p><strong>Results: </strong>In this study population of 4,282 individuals, 352 individuals with an ACR of 30 mg/g or higher were considered to have albuminuria. The prevalence of constipation was higher in the albuminuria group compared to the non-albuminuric group (6.4% vs. 3.5%, <i>p</i> = 0.002). The unadjusted model (Model I) showed an increased risk of ACR associated with constipation (OR 1.81, 95% CI 1.13-2.91, <i>p</i> = 0.014). After controlling for gender, age, race/ethnicity, marital status, and education level in Model II, the association between constipation and ACR remained significant (OR 2.20, 95% CI 1.34-3.60, <i>p</i> = 0.002). Upon further adjustment for BMI, smoking status, alcohol consumption, diabetes, hypertension, arthritis, asthma, coronary heart disease, liver disease, cancer, blood urea nitrogen (BUN), serum creatinine (Scr), uric acid (UA) and estimated glomerular filtration rate (eGFR) in Model III, the positive association between constipation and ACR was still significant (OR 1.88, 95% CI 1.09-3.23, <i>p</i> = 0.023). Subgroup analyses, stratified by gender, age, smoking status, alcohol consumption, BMI, hypertension, and diabetes, showed no statistically significant interactions (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>In summary, this study found a positive association between constipation and urinary albumin excretion rate. The significant association between constipation and ACR highlights the need for clinicians to monitor urinary albumin levels in patients with constipation.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1477148"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.","authors":"Chen Xu, Siyuan Bi, Wenxin Zhang, Lin Luo","doi":"10.3389/fnut.2025.1570800","DOIUrl":"https://doi.org/10.3389/fnut.2025.1570800","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fnut.2024.1424972.].</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1570800"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of dietary intake of saturated fatty acids with obstructive sleep apnea: mediating effects of Life's Crucial 9.","authors":"Ruoyu Gou, Lili Chen, Zeyi Cheng, Jiawei Cun, Guanghua Li","doi":"10.3389/fnut.2025.1503815","DOIUrl":"10.3389/fnut.2025.1503815","url":null,"abstract":"<p><strong>Introduction: </strong>Obstructive sleep apnea (OSA) is a global public health issue. Life's Crucial 9 (LC9) is recognized as a powerful tool for assessing cardiovascular health. Although the etiology of OSA remains unclear, saturated fatty acids (SFAs) and cardiovascular health are increasingly regarded as a non-negligible element. This study aims to assess the association between dietary intake of SFAs and the risk of OSA, and the mediating effect of LC9.</p><p><strong>Methods: </strong>Based on the National Health and Nutrition Examination Survey (NHANES), dietary questionnaires of participant were collected, and the average values of 24-h dietary recall data over 2 days were obtained. A continuous cross-sectional analysis with dietary energy adjustment was employed. Weighted multivariable logistic regression models were used to estimate the weighted odds ratios (ORs) and their 95% confidence intervals (CIs) for SFAs and OSA. Evaluate the mediating role of LC9 in the relationship between SFAs and OSA.</p><p><strong>Results: </strong>A total of 13,563 participants aged 20 years and above were included in this study. The intakes of Sfa 4.0 and LC9 among participants with OSA were significantly lower than those in the normal population. After adjusting for confounding factors, total SFAs could increase the risk of OSA [Model 1, Q3, 0.03, 1.49 (1.03, 2.15); Model 2, Q3, 0.04, 1.47 (1.01, 2.13)]. It was emphasized that dietary intake of Sfa 12.0, Sfa 14.0, and Sfa 16.0 were protective factors for OSA, especially among participants aged 45-64 years and white individuals. Moreover, Sfa 12.0 exhibited a better protective effect in female participants [Q3, 0.04, 0.66 (0.45, 0.99)]. In addition, the cardiovascular health score - LC9 had a mediating effect in Sfa4.0 on OSA [Proportion of mediation: -0.035, 95% CI: (-0.058, -0.01); <i>p</i>= 0.002]. There was a nonlinear relationship between dietary intake of Sfa 12.0, Sfa 16.0, and Sfa 18.0 and OSA (<i>P-Nonlinear</i> = 0.013).</p><p><strong>Discussion: </strong>These findings suggest that dietary mixtures of saturated fatty acids increase the risk of OSA. Among them, SFA 4:0 can increase the risk of OSA through the level of cardiovascular health. However, contrary to traditional beliefs, long-chain saturated fatty acids can reduce the risk of OSA.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1503815"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parenteral nutritional support in surgical patients: expert consensus statements regarding intravenous lipid emulsions containing omega-3 fatty acids.","authors":"Robert G Martindale, David C Evans, Dan Waitzberg, Malissa Warren, Manpreet S Mundi, Stanislaw Klek, Paul E Wischmeyer, Martin D Rosenthal","doi":"10.3389/fnut.2025.1546089","DOIUrl":"10.3389/fnut.2025.1546089","url":null,"abstract":"<p><strong>Objectives: </strong>The International Lipids in Parenteral Nutrition (PN) Summit was convened to offer practical guidance and expert consensus opinion regarding the use of intravenous lipid emulsions (ILEs) in various clinical settings. Herein, we briefly review aspects from this summit that are of particular importance for surgical/hospitalized patients.</p><p><strong>Methods: </strong>Summit participants identified and discussed new evidence, data, and analyses, that potentially influence the benefits and risks of ILEs in PN or their use in clinical practice. The summit meeting consisted of expert presentations that assessed recent clinical data and best practice, followed by periodic panel discussions to formulate consensus statements. Consensus statements were voted on, anonymously, by the meeting attendees.</p><p><strong>Results: </strong>This review briefly summarizes the rationale for considering ILE choice as a central component of any PN strategy for surgical/hospitalized patients. Thereafter, special patient populations are considered, such as surgery-related intestinal failure, major trauma, and those with chronic critical illnesses. Expert consensus statements are also provided to help bridge the gaps between evidence and clinical practice, hence complementing formal PN societal guideline recommendations.</p><p><strong>Conclusion: </strong>The choice of ILE in PN, particularly those containing fish oil, can play a vital role in improving outcomes for surgical patients.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1546089"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Various steaming durations alter digestion, absorption, and fermentation by human gut microbiota outcomes of <i>Polygonatum cyrtonema</i> Hua polysaccharides.","authors":"Weijing Wu, Yanling Wang, Ping Yi, Xufeng Su, Yan Mi, Lanlan Wu, Qianglai Tan","doi":"10.3389/fnut.2025.1561857","DOIUrl":"https://doi.org/10.3389/fnut.2025.1561857","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fnut.2024.1466781.].</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1561857"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: The nutritional and health benefits of <i>Vaccinium</i> berries.","authors":"Paulina M Nowaczyk, Patrick Turck, Małgorzata Jamka","doi":"10.3389/fnut.2025.1561116","DOIUrl":"10.3389/fnut.2025.1561116","url":null,"abstract":"","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1561116"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between dietary inflammatory index and anemia in individuals with diabetes mellitus.","authors":"Nengneng Cao, Jinlan Li, Chun Ling, Jiajia Wang, Furun An","doi":"10.3389/fnut.2025.1538696","DOIUrl":"10.3389/fnut.2025.1538696","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus (DM) has emerged as a significant component of the global health crisis, closely linked with anemia. Studies have demonstrated a connection between anemia and inflammation. The Dietary Inflammatory Index (DII) is a novel metric for evaluating the overall inflammatory or anti-inflammatory impact of dietary intake. While risk factors for DM are linked to an unhealthy diet, there is currently insufficient research regarding the correlation between DII and anemia among individuals with DM. This study aims to investigate the correlation between DII and anemia among American individuals with DM.</p><p><strong>Methods: </strong>This study utilized data from the National Health and Nutrition Examination Survey (NHANES) database, encompassing 4,435 participants recorded between 2007 and 2016. We conducted a weighted multivariable logistic regression analysis to investigate the correlation between the DII and anemia of individuals with DM. Furthermore, we explored their relationship through subgroup analysis and smooth curve fitting techniques.</p><p><strong>Results: </strong>This study comprised 726 participants with DM who were anemic and 3,709 who were non-anemic; notably, anemic participants exhibited elevated DII scores (2.05 ± 1.50 vs. 1.70 ± 1.59). In the fully adjusted model, we noted a positive correlation between the DII and anemia (Odds Ratio [OR] = 1.09, 95% Confidence Interval [CI] =1.03 to 1.16, <i>p</i> = 0.004). Participants in the fully adjusted model had a 9% higher prevalence of anemia for each unit increase in DII. The significant association between anemia and DII persisted even after subgroup analysis. Smooth curve fitting analysis revealed a positive correlation between DII and anemia.</p><p><strong>Conclusion: </strong>There is a positive correlation between DII and anemia in individuals with DM in the United States. It provides important insights into dietary management strategies for diabetic patients with anemia.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1538696"},"PeriodicalIF":4.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}