Frontiers in Nutrition最新文献

{"title":"Angiotensin-I-converting enzyme inhibitory peptides from eel (<i>Anguilla japonica</i>) bone collagen: preparation, identification, molecular docking, and protective function on HUVECs.","authors":"Huan Xiang, Hui Huang, Yanqiu Shao, Shuxian Hao, Laihao Li, Ya Wei, Shengjun Chen, Yongqiang Zhao","doi":"10.3389/fnut.2024.1462656","DOIUrl":"https://doi.org/10.3389/fnut.2024.1462656","url":null,"abstract":"<p><strong>Introduction: </strong>Hypertension is a chronic cardiovascular disease, which can trigger some disease such as heart failure, loss of vision or kidney. There were various peptides derived from food that are recognized for their ability to inhibit ACE activity, potentially leading to a reduction in blood pressure levels <i>in vivo</i>. The primary objective of this research is to discover ACE inhibitory peptides from protein hydrolysates of eel bone collagen (EBCHs).</p><p><strong>Methods: </strong>To begin, EBCHs were created and then divided through the process of ultrafiltration. The second step involved screening of peptides capable of inhibiting ACE by combining peptidomics and molecular docking. And the mechanism by which ACE interacts with peptides has been studied. Finally, the hypotensive mechanism of identified peptide through cell experiments with HUVEC (Human Umbilical Vein Endothelial Cells).</p><p><strong>Results: </strong>Eel (<i>Anguilla japonica</i>) bone collagen was hydrolyzed by alcalase and the hydrolysate was separated into three fractions, among which the F2 displayed a higher level of ACE inhibitory activity. According to molecular docking calculations, a total of 615 peptides were identified through nano-HPLC-MS/MS, with the prediction of seven newly discovered ACE inhibitory peptides (PMGPR, GPMGPR, GPAGPR, GPPGPPGL, GGPGPSGPR, GPIGPPGPR, GPSGAPGPR). Notably, GPPGPPGL had the lowest IC₅₀ value of 535.84 μM among the identified peptides, indicating its potency as an ACE inhibitor. The ACE S2 pocket formed hydrogen and hydrophobic interactions with GPPGPPGL. Lineweaver-Burk plots revealed that GPPGPPGL competitively bound to ACE's active site residues. Treatment with GPPGPPGL significantly increased nitric oxide secretion (<i>p</i> < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.</p><p><strong>Discussion: </strong>Our findings suggest that combining peptidomics with molecular docking is effective for rapidly screening ACE inhibitory peptides. Future studies should assess the bioavailability and <i>in vivo</i> activity of the identified peptide GPPGPPGL from EBCHs.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1462656"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the gastric digestion behavior of commercial infant formulae using an <i>in vitro</i> dynamic infant digestion model.","authors":"Faith Bernadette Descallar, Debashree Roy, Xin Wang, Peter Zhu, Aiqian Ye, Yichao Liang, Shikha Pundir, Harjinder Singh, Alejandra Acevedo-Fani","doi":"10.3389/fnut.2024.1507093","DOIUrl":"https://doi.org/10.3389/fnut.2024.1507093","url":null,"abstract":"<p><p>The gastric digestion behavior of different commercial Stage 1 infant formulae (for 0-6 months) with different formulation backgrounds was investigated using an <i>in vitro</i> dynamic infant human gastric simulator (iHGS). The microstructural arrangements of the protein and lipid, colloidal stability and protein hydrolysis during digestion were elucidated. During gastric digestion, casein-dominant formulations showed a higher extent of aggregation due to their high proportion of casein micelles that underwent coagulation upon acidification and via the action of pepsin. The extensive protein coagulation/curd formation in casein-dominant infant formulae slowed the rate of protein hydrolysis and resulted in the retention of caseins in the iHGS for longer times. Confocal micrographs showed that oil droplets were entrapped in the curd particles of casein-dominant infant formulae, which consequently slowed the gastric emptying of lipids. Conversely, whey-dominant formulations showed a lower degree of protein aggregation that resulted in faster protein hydrolysis and rapid protein and lipid emptying from the iHGS. It was also revealed that whey-dominant infant formulae in the presence of biopolymers increased the viscosity of gastric chyme and induced the flocculation of oil droplets. This altered the rate of protein hydrolysis and emptying of lipids. Correlation analyses depicted the overall kinetics of gastric emptying of macronutrients during digestion and comprised two stages: (i) driven by the continuous stomach emptying and (ii) influenced by aggregation and coalescence indices. The present study highlights the similarities and differences in the digestion behaviors of commercial infant formulae based on important ingredients such as types of proteins and biopolymers, regardless of the formulation or processing histories.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1507093"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of different types of milk with depression and anxiety: a prospective cohort study and Mendelian randomization analysis.","authors":"Chunying Wu, Yusheng Liu, Yigui Lai, Qiang Wang, Siqi Wu, Huijie Fan, Yanyan Liu, Xiaoshan Zhao, Xuefeng Jiang","doi":"10.3389/fnut.2024.1435435","DOIUrl":"https://doi.org/10.3389/fnut.2024.1435435","url":null,"abstract":"<p><strong>Background: </strong>The relationship between different types of milk and depression and anxiety remains unclear, with limited evidence from prospective cohort studies. This study aims to evaluate this relationship using data from the UK Biobank cohort and to explore its potential causality through Mendelian randomization (MR) analysis.</p><p><strong>Methods: </strong>Cox proportional hazards models were used to assess the association between different milk types and the risk of depression and anxiety among 357,568 UK Biobank participants free of these conditions at baseline. To further explore causality, a 2-sample MR analysis was conducted using data from the FinnGen study.</p><p><strong>Results: </strong>During a median follow-up period of 13.5 years (interquartile range, 12.6-14.2 years), among 357,568 participants (mean [SD] age, 56.83 [8.06] years, 171,246 male individuals [47.9%]), a total of 13,065 and 13,339 participants were diagnosed with depression and anxiety, respectively. In the fully adjusted model (adjusted for sociodemographics characteristics, lifestyle behaviors and health indicators), full cream milk was related to a lower risk of anxiety (HR = 0.84, 95% CI: 0.75-0.94). Semi-skimmed milk had a lower risk of depression (HR = 0.88, 95% CI: 0.80-0.96) and anxiety (HR = 0.90, 95% CI: 0.82-0.98). No significant relationships were found between skimmed milk and depression/anxiety. Other types were related to an increased risk of depression (HR = 1.14, 95% CI: 1.02-1.28). After Bonferroni correction, the 2-sample MR analysis revealed a potential protective causal relationship between semi-skimmed milk and depression (OR = 0.83, 95% CI: 0.73-0.95, <i>p</i> = 0.006) and anxiety (OR = 0.71, 95% CI: 0.59-0.85, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>These findings indicate that semi-skimmed milk consumption may be linked to a lower risk of depression and anxiety, potentially highlighting its role in dietary strategies to promote mental health.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1435435"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyphenol-rich extracts enhance growth, immune function, and antioxidant defense in juvenile rainbow trout (<i>Oncorhynchus mykiss</i>).","authors":"Aghil Mansoori, Hamid Allaf Noveirian, Seyed Hossein Hoseinifar, Mirmasoud Sajjadi, Ghasem Ashouri, Roberta Imperatore, Marina Paolucci","doi":"10.3389/fnut.2024.1487209","DOIUrl":"https://doi.org/10.3389/fnut.2024.1487209","url":null,"abstract":"<p><strong>Introduction: </strong>The present study was conducted to investigate the effects of PMIX, a polyphenol-rich extract mixture from chestnut wood and olive, on growth performance, hematological parameters, immunity in serum and skin mucus, hepatic antioxidant enzymes, and intestinal cytokine expression in rainbow trout (<i>Oncorhynchus mykiss</i>).</p><p><strong>Methods: </strong>Four experimental diets containing 0 g PMIX kg^-1 diet (control, C), 0.5 g PMIX kg^-1 diet (P0.5), 1 g PMIX kg^-1 diet (P1), and 2 g PMIX kg^-1 diet (P2) were fed to rainbow trout in an eight-week feeding trial. Triplicate groups of fish received each treatment. Growth performance, feed conversion ratio, protein efficiency, hepatosomatic and viscerosomatic indices, hematological parameters, immunity markers, hepatic antioxidant enzyme activities, and intestinal cytokine expression were determined.</p><p><strong>Results: </strong>PMIX supplementation significantly improved feed conversion ratios, while groups P0.5 and P1 evidenced an increase in growth performance along with protein efficiency ratios. It also showed decreased hepatosomatic and viscerosomatic indices in the P1 group. Except for higher percentages of monocytes in P0.5 and P1, most hematological parameters of the fish did not differ from that of the control. Serum lysozyme and respiratory burst activities were heightened in all PMIX-treated groups, and the skin mucus lysozyme activity was enhanced in P1. The blood phagocytic activity and phagocytic index, serum immunoglobulin, total protein, and bactericidal activity against <i>A. hydrophila</i> did not change. Hepatic superoxide dismutase activity significantly increased in P1 and P2, even though catalase activity did not change. Intestinal interleukin-6 expression was upregulated in all PMIX-treated groups, while tumor necrosis factor-alpha and interleukin-1 beta were upregulated in P1, P2, and P0.5 respectively.</p><p><strong>Discussion: </strong>The present results evidence that dietary polyphenols from chestnut wood and olive extracts enhance growth performance, antioxidant capacity, and several immunological parameters in the blood, skin mucus, and intestine of rainbow trout. A suitable supplementation level was 1 g PMIX kg^-1 diet to separate these improvements.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1487209"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of GLIM criteria for hospital malnutrition diagnosis by comparison of three different anthropometric approaches to evaluate reduced muscle mass: a prospective cohort study.","authors":"Mostafa Shahraki Jazinaki, Mohammad Safarian, Seyyed Mostafa Arabi, Jamshid Jamali, Abdolreza Norouzy","doi":"10.3389/fnut.2024.1438158","DOIUrl":"https://doi.org/10.3389/fnut.2024.1438158","url":null,"abstract":"<p><strong>Background and aim: </strong>The Global Leadership Initiative on Malnutrition (GLIM) recently proposed a new malnutrition diagnostic tool known as the GLIM criteria. The GLIM criteria need confirmed validation before being widely used in each population or healthcare system. This study aimed to investigate the validation of the GLIM criteria for malnutrition diagnosis in hospitalized patients.</p><p><strong>Methods: </strong>The content validity was assessed by calculating the content validity ratio (CVR) and content validity index (CVI). Subjective global assessment (SGA) is considered the reference tool to diagnose malnutrition in concurrent validation. In addition, the Kuder-Richardson 20 was used to evaluate the reliability of the GLIM criteria. Furthermore, hospital mortality, length of hospitalization (LOS), prolonged hospital stays (LOS >6 days), 30-day hospital readmission, and 30- and 60-day mortality were identified as malnutrition-related outcomes in predictive validity.</p><p><strong>Results: </strong>A total of 332 adult/elderly hospitalized patients (median age: 58 (IQR: 24.7), 60.5% men) were enrolled to present the study. Appling GLIM criteria by considering the calf circumference < 31 cm in both genders or mid-upper arm (MUAC) < 23 cm in men and MUAC <22 cm in women as reduced muscle mass had an appropriate accuracy (84.6 and 83.4%, respectively), good ability to distinguish malnourished patients (AUC ROC: 0.85 and 0.83, respectively), satisfactory sensitivity (89.58 and 84.02%, respectively), and satisfactory specificity (81 and 83%, respectively) compared to the SGA tool. Furthermore, the reliability of the GLIM criteria for malnutrition diagnosis in hospitalized patients was acceptable in all 3 applied approaches (KR-20 > 0.5). The malnutrition diagnosed by GLIM criteria could significantly predict the odds of prolonged hospital stays, 30-day hospital readmission, and 60-day mortality, while it had no significant association with the risk of hospital mortality.</p><p><strong>Conclusion: </strong>The current study revealed that applying GLIM criteria had satisfactory validity in diagnosing hospital malnutrition in non-critically ill hospitalized patients.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1438158"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autophagy and nutrigenomics: a winning team against chronic disease and tumors.","authors":"Roberto Chiarelli, Fabio Caradonna, Flores Naselli","doi":"10.3389/fnut.2024.1409142","DOIUrl":"https://doi.org/10.3389/fnut.2024.1409142","url":null,"abstract":"<p><p>Autophagy, a vital cell process, has garnered attention for its role in various diseases and potential therapeutic interventions. Dysregulation of autophagy contributes to conditions such as metabolic diseases, neurodegenerative disorders, and cancer. In diseases such as diabetes, autophagy plays a crucial role in islet β-cell maintenance and glucose homeostasis, offering potential targets for therapeutic intervention. Nutrigenomics, which explores how dietary components interact with the genome, has emerged as a promising avenue for disease management. It sheds light on how diet influences gene expression and cellular processes, offering personalized approaches to disease prevention and management. Studies have showed the impact of specific dietary components, such as polyphenols and omega-3 fatty acids, on autophagy processes, suggesting their potential therapeutic benefits in neurodegenerative conditions and metabolic disorders. In cancer, autophagy's dual role in either suppressing tumorigenesis or promoting cancer cell survival underscores the importance of understanding its modulation through dietary interventions. Combined with conventional chemotherapy drugs, dietary compounds show synergistic effects in cancer treatment. Furthermore, phytochemicals such as indicaxanthin have been found to epigenetically regulate genes involved in autophagy, offering novel insights into personalized cancer therapies. This comprehensive review has the aim to study the autophagy in a combined view with nutrigenomics effects of some dietary molecules in maintaining cellular homeostasis and responding to pathological stimuli. Overall, the intersection of autophagy and nutrigenomics effect of bioactive compounds holds promise for developing targeted interventions for various diseases, emphasizing the significance of dietary interventions in disease prevention and management.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1409142"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoding diets: insights on ultra-processed food consumption among Lebanese adults from the updated LEBANese natiONal food consumption survey (LEBANON-FCS).","authors":"Maroun Khattar, Nikolaos Tzenios, Esraa Antar, Dana Malli, Maha Hoteit","doi":"10.3389/fnut.2024.1475223","DOIUrl":"https://doi.org/10.3389/fnut.2024.1475223","url":null,"abstract":"<p><strong>Introduction: </strong>Ultra-processed foods are evident to play a role in the development of nutrition-related non-communicable diseases (NR-NCDs). There's a scarcity of data in the Eastern Mediterranean Region (EMR) regarding ultra-processed food consumption, which highlights the need for such data in this region that is witnessing a nutrition transition. This study was conducted to assess the dietary pattern of Lebanese adults according to different degrees of food processing.</p><p><strong>Methods: </strong>A cross-sectional study involving a nationally representative sample (<i>n</i> = 444) of Lebanese adults (18-64 years) was conducted over the course of 5 months. A validated food frequency questionnaire and two non-consecutive 24-h recalls were used to collect the dietary intake. Sociodemographic and medical characteristics were collected using a validated questionnaire. Anthropometric measurements were taken by trained dietitians. Food items were classified according to the NOVA food classification system, and the percent contribution of every type of processing to the energy intake was calculated.</p><p><strong>Results: </strong>Ultra-processed foods contributed to the highest percent of energy intake in the sample (46.7%), followed by unprocessed and minimally processed foods (39.6%). Being male, and younger increased the odds of higher ultra-processed food intake; being employed and food secure increased the odds of a higher NOVA-UPF score. Compared with participants in Beirut, participants residing in North Lebanon and Akkar had higher odds of having a high UPF intake and lower odds of having a high NOVA-UPF score. The three most contributing food items to energy intake were ultra-processed (breads and breakfast cereals, fast foods, sweets and desserts). Compared to the unprocessed and minimally processed food diet fraction, the ultra-processed food diet fraction was significantly higher in sodium and thiamin and lower in proteins, fiber, and essential vitamins and minerals such as vitamins A, D, B12, folate, iron, calcium, and magnesium.</p><p><strong>Conclusion: </strong>UPF intake was the main contributor to TEI, and the intake was considerably higher among those who reported having renal disease, younger adults, and males. In comparison to the minimally processed diet fraction, the UPF diet fraction was found to have considerably greater levels of sodium and thiamin and lower levels of proteins, fiber, and essential vitamins and minerals. The study findings call for public health policies and interventions to encourage the consumption of minimally processed foods and decrease the consumption of ultra-processed foods, especially sweets and sweetened beverages, which are especially problematic.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1475223"},"PeriodicalIF":4.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11656934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of fish to food and nutrition security in Southern Africa: challenges and opportunities in fish production.","authors":"Sahya Maulu, Confred Godfrey Musuka, Montshwari Molefe, Tlou Kevin Ngoepe, Ndakalimwe Naftal Gabriel, Joseph Mphande, Msumenji Phiri, Valdemiro Muhala, Messias Alfredo Macuiane, Mzime Regina Ndebele-Murisa, Oliver Jolezya Hasimuna, Thethela Bokhutlo, Mexford Mulumpwa, Victoria Ndinelago Erasmus, Wilson Jere, Chipo Hazel Dekesa, Chipo Plaxedes Mubaya, Manecas Francisco Baloi, Johannes Angala Iitembu, Enock Siankwilimba, Lin Zhang","doi":"10.3389/fnut.2024.1424740","DOIUrl":"https://doi.org/10.3389/fnut.2024.1424740","url":null,"abstract":"<p><p>This study investigated the role of fish in addressing food and nutrition security challenges in Southern Africa, focusing on 10 countries including Angola, Zambia, Malawi, Mozambique, Namibia, Botswana, Zimbabwe, Lesotho, Eswatini, and South Africa. It examined the current state of food and nutrition security, fish production, and fish consumption patterns. Additionally, the study investigated the challenges and opportunities to enhance fish production in these countries thereby enhancing food and nutrition security. The findings revealed persistent challenges such as a high prevalence of food insecurity and malnutrition throughout the region. Fish production is hindered by overexploitation of fishery resources, inadequate fisheries management, susceptibility to climate-related shocks, limited investments in aquaculture, and inadequate access to input supplies such as quality fish seed and feed. Despite these obstacles, opportunities exist to promote sustainable fish production to enhance food security and nutrition. Countries endowed with extensive coastlines and inland waters exhibit significant potential for fishery development, while landlocked nations are increasingly exploring aquaculture as a viable solution. Addressing the challenges in fish production and capitalizing on opportunities requires comprehensive governance, technological innovation, policy interventions, and investment to ensure the sustainability and resilience of the fisheries and aquaculture industries in the region.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1424740"},"PeriodicalIF":4.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between carbohydrate intake and sleep patterns.","authors":"Yan Zhao, Hailong Guo","doi":"10.3389/fnut.2024.1491999","DOIUrl":"https://doi.org/10.3389/fnut.2024.1491999","url":null,"abstract":"<p><strong>Background: </strong>A healthy dietary habit may contribute to good sleep quality. The present study investigates the correlation between the quality and quantity of daily carbohydrate consumption and poor sleep patterns.</p><p><strong>Methods: </strong>The exposures of interest included low-and high-quality carbohydrate consumption and total daily carbohydrate consumption. Subjects were classified into four different carbohydrate consumption patterns: Pattern 1 was characterized by high-quality carbohydrates below the median and low-quality carbohydrates above the median; Pattern 2 included both high-and low-quality carbohydrates below the median; Pattern 3 was defined as high-and low-quality carbohydrates above the median; Pattern 4 referred to high-quality carbohydrates above the median and low-quality carbohydrates below the median. The comprehensive sleep patterns included three different sleep behaviors: sleep duration, daytime sleepiness, and snoring, which were used to score sleep patterns. A score ranging from 0 to 1 was classified as having a healthy sleep pattern, while a score between 2 and 3 showed poor sleep patterns. Survey-weighted multivariable logistic regression analyses were adopted.</p><p><strong>Results: </strong>In the multivariate analysis, individuals who consumed more high-quality carbohydrates were linked to a decreased likelihood of experiencing poor sleep patterns [odds ratio (OR) 0.71; 95% confidence interval (CI) 0.62-0.81], while increased consumption of low-quality carbohydrates (OR 1.39; 95%CI 1.20-1.61) and total daily carbohydrates (OR 1.31; 95%CI 1.10-1.57) was related to an elevated risk of poor sleep patterns. Participants who adhered to carbohydrate intake pattern 4 exhibited a 36% lower risk of poor sleep patterns than those who followed carbohydrate intake pattern 1 (OR 0.64; 95%CI 0.56-0.74). There was a positive correlation between elevated added sugar consumption and an increased probability of developing poor sleep patterns. In contrast, an elevated intake of whole grains, fruits, or non-starchy vegetables was related to a decreased likelihood of experiencing poor sleep patterns.</p><p><strong>Conclusion: </strong>The increased consumption of low-quality carbohydrates may heighten the susceptibility to poor sleep patterns, whereas the increased consumption of high-quality carbohydrates may mitigate the risk of developing poor sleep patterns.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1491999"},"PeriodicalIF":4.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11652137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Association between different composite dietary antioxidant indexes and constipation in American male adults: a cross-sectional study.","authors":"Wei Sun, Yuchao Wang, Lu Han, Yinshi Liu, Hongru Liu, Yunbing Tong, Ziying Jiang, Chen Xu, Daqing Sun","doi":"10.3389/fnut.2024.1530119","DOIUrl":"https://doi.org/10.3389/fnut.2024.1530119","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fnut.2024.1404400.].</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"11 ","pages":"1530119"},"PeriodicalIF":4.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}