Frontiers in Chemistry最新文献_第10页

Progress in antibacterial applications of nanozymes. 纳米酶的抗菌应用进展。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1478273

Keyuan Zhao, Ye Zhao, Yuwei Wang, Bo Han, Meiling Lian

{"title":"Progress in antibacterial applications of nanozymes.","authors":"Keyuan Zhao, Ye Zhao, Yuwei Wang, Bo Han, Meiling Lian","doi":"10.3389/fchem.2024.1478273","DOIUrl":"https://doi.org/10.3389/fchem.2024.1478273","url":null,"abstract":"Bacterial infections are a growing problem, and antibiotic drugs can be widely used to fight bacterial infections. However, the overuse of antibiotics and the evolution of bacteria have led to the emergence of drug-resistant bacteria, severely reducing the effectiveness of treatment. Therefore, it is very important to develop new effective antibacterial strategies to fight multi-drug resistant bacteria. Nanozyme is a kind of enzyme-like catalytic nanomaterials with unique physical and chemical properties, high stability, structural diversity, adjustable catalytic activity, low cost, easy storage and so on. In addition, nanozymes also have excellent broad-spectrum antibacterial properties and good biocompatibility, showing broad application prospects in the field of antibacterial. In this paper, we reviewed the research progress of antibacterial application of nanozymes. At first, the antibacterial mechanism of nanozymes was summarized, and then the application of nanozymes in antibacterial was introduced. Finally, the challenges of the application of antibacterial nanozymes were discussed, and the development prospect of antibacterial nanozymes was clarified.","PeriodicalId":12421,"journal":{"name":"Frontiers in Chemistry","volume":"12 ","pages":"1478273"},"PeriodicalIF":3.8,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142389266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and electrochemical studies of NaCoPO₄ as an efficient cathode material using natural deep eutectic solvents for aqueous rechargeable sodium-ion batteries. 利用天然深共晶溶剂合成 NaCoPO4 作为水性可充电钠离子电池的高效阴极材料并对其进行电化学研究。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-20 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1440639

C V V Eswara Rao, Sannapaneni Janardan, H Manjunatha, K Venkata Ratnam, Sandeesh Kumar, K Chandrababu Naidu, Shivendu Ranjan

{"title":"Synthesis and electrochemical studies of NaCoPO4 as an efficient cathode material using natural deep eutectic solvents for aqueous rechargeable sodium-ion batteries.","authors":"C V V Eswara Rao, Sannapaneni Janardan, H Manjunatha, K Venkata Ratnam, Sandeesh Kumar, K Chandrababu Naidu, Shivendu Ranjan","doi":"10.3389/fchem.2024.1440639","DOIUrl":"10.3389/fchem.2024.1440639","url":null,"abstract":"In this work, sodium cobalt phosphate (NaCoPO4) was successfully prepared by a cost-effective ionothermal method using a deep eutectic solvent (DES) for the first time. The synthesized NaCoPO4 was used to fabricate a cathode material for aqueous rechargeable sodium-ion batteries. The surface morphology of the prepared materials and its compositional analysis were done by using field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray (EDX) analysis, respectively. The X-ray diffraction (XRD), SEM, and EDX studies revealed that the material has orthorhombic-shaped particle morphology with uniform distribution and is in nanoscale (approximately 50 nm). The nature of the cation inserted (Na+ ion insertion) was confirmed by recording CV profiles at different concentrations of the Na2SO4 electrolyte. The reversibility of the electrode redox reaction was studied by varying the scan rate in CV studies, and it was found that the electrode exhibits a reversible behavior with a resistive behavior. In GCPL studies, the cell TiO2/2MNa2SO4/NaCoPO4 showed significant reversibility with a prominent discharge capacity of 85 mAh g-1 at 0.1°C and 88% of capacity retention after 100 cycles. Thus, the prepared materials could be used as an effective futuristic alternative battery material for rechargeable batteries.","PeriodicalId":12421,"journal":{"name":"Frontiers in Chemistry","volume":"12 ","pages":"1440639"},"PeriodicalIF":3.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11452910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142383295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication and growth mechanism of t-selenium nanorods during laser ablation and fragmentation in organic liquids. 有机液体中激光烧蚀和碎裂过程中 t-硒纳米棒的制造和生长机理。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-20 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1449570

Ilya V Baimler, Alexander V Simakin, Anastasia O Dikovskaya, Valery V Voronov, Oleg V Uvarov, Alexander A Smirnov, Alexey V Sibirev, Alexey S Dorokhov, Sergey V Gudkov

{"title":"Fabrication and growth mechanism of t-selenium nanorods during laser ablation and fragmentation in organic liquids.","authors":"Ilya V Baimler, Alexander V Simakin, Anastasia O Dikovskaya, Valery V Voronov, Oleg V Uvarov, Alexander A Smirnov, Alexey V Sibirev, Alexey S Dorokhov, Sergey V Gudkov","doi":"10.3389/fchem.2024.1449570","DOIUrl":"10.3389/fchem.2024.1449570","url":null,"abstract":"Introduction: The process of forming selenium nanoparticles with various shapes and structures through laser ablation and fragmentation in various solvents has been explored.Methods: Laser ablation and laser fragmentation techniques were employed using nanosecond Nd:YAG second harmonic laser irradiation in 9 different working fluids, including water. The characteristics of the resulting nanoparticles were assessed using transmission electron microscopy (TEM), dynamic light scattering (DLS), spectroscopy, and X-ray diffraction (XRD) methods.Results: Laser ablation and subsequent laser fragmentation of some organic solvents, such as ethanol, propanol-2, isobutanol, polyethylene glycol, and diethanolamine, have been found to produce trigonal selenium in the form of elongated nanorods approximately 1 μm long and 200 nm thick, with a well-defined crystal structure. In contrast, the use of deionized water, acetone, glycerol, and benzene as solvents results in the formation of spherical amorphous nanoparticles approximately 100 nm in diameter.Discussion: The polarity of the solvent molecules has been shown to influence the growth of crystalline selenium nanorods in solution during laser ablation and laser fragmentation. Generally, polar solvents hinder the growth of crystalline nanorods, due to interactions between selenium and solvent molecules. Nonpolar solvents, on the other hand, allow for laser fragmentation to reduce particle size and initiate the epitaxial growth of elongated, crystalline selenium nanorods.","PeriodicalId":12421,"journal":{"name":"Frontiers in Chemistry","volume":"12 ","pages":"1449570"},"PeriodicalIF":3.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities. 基于结构的虚拟筛选，发现具有抗肝癌活性的新型凝血酶抑制剂。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-20 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1451574

Xiaoxi Zhang, Xumei Zheng, Chun Han, Lintao Wu

{"title":"Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities.","authors":"Xiaoxi Zhang, Xumei Zheng, Chun Han, Lintao Wu","doi":"10.3389/fchem.2024.1451574","DOIUrl":"10.3389/fchem.2024.1451574","url":null,"abstract":"Introduction: Hepatic carcinoma (HCC) is one of the most lethal malignant tumors in the world, and new treatment regimens for this disease are urgently needed. Studies have shown that thrombin stimulates tumor progression by forming fibrin and activating platelets. Dabigatran etexilate, a thrombin inhibitor, can inhibit the activity of thrombin and prevent the proliferation and metastasis of HCC in cells and nude mice.Methods: The present study was designed to find thrombin inhibitors with novel skeletons, and further confirm the correlation between thrombin inhibition and HCC prevention to identify potential anti-HCC drug leads.Results and discussion: The potential thrombin inhibitors were firstly screened in the Topscience Database, and 20 potential active molecules were found by molecular docking. The effect of these molecules on thrombin inhibition, coagulation and tumor proliferation were evaluated, and the definite activity of ZXX-4 was identified. Further in vivo assays in nude mice showed that ZXX-4 inhibited tumor proliferation in nude mice, reduced tumor metastasis, and enhanced the clinical efficacy of first-line drug sorafenib for the treatment of HCC. ZXX-4 can be further explored as an anti-tumor lead compound with a novel skeleton, and inhibition of thrombin can serve as a potential treatment strategy for HCC.","PeriodicalId":12421,"journal":{"name":"Frontiers in Chemistry","volume":"12 ","pages":"1451574"},"PeriodicalIF":3.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Greening the way: Emerging green technologies in process intensification. 社论：绿色之路：工艺集约化中的新兴绿色技术。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-19 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1487667

Georgios Psakis, Sholeem Griffin, Maria Dimopoulou, Athanasios Angelis-Dimakis, Jose Manuel Lorenzo

引用次数: 0

Editorial: Advances in wound repair and regeneration: novel materials, targets and applications. 社论：伤口修复和再生的进展：新型材料、目标和应用。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-19 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1487091

Xinwei Cheng, Jia Zhou

引用次数: 0

The application of nanodiscs in membrane protein drug discovery & development and drug delivery 纳米盘在膜蛋白药物研发和药物输送中的应用

IF 5.5 3区化学

Frontiers in Chemistry Pub Date : 2024-09-18 DOI: 10.3389/fchem.2024.1444801

Yingkui Dong, Huan Tang, Han Dai, Hongxin Zhao, Junfeng Wang

引用次数: 0

Highlighting multicomponent reactions as an efficient and facile alternative route in the chemical synthesis of organic-based molecules: a tremendous growth in the past 5 years 强调多组分反应是有机基分子化学合成中一种高效、简便的替代途径：在过去 5 年中取得了巨大发展

IF 5.5 3区化学

Frontiers in Chemistry Pub Date : 2024-09-18 DOI: 10.3389/fchem.2024.1469677

Reagan Lehlogonolo Mohlala, Thompho Jason Rashamuse, Elena Mabel Coyanis

引用次数: 0

Editorial: Novel compounds from chemistry to druggable candidates. 社论：从化学到药物候选的新型化合物。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-17 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1494407

Pete Rose, Jawad Nasim, Yi-Zhun Zhu

引用次数: 0

A non-classical synthetic strategy for organic mesocrystals. 有机介晶的非经典合成策略。

IF 3.8 3区化学

Frontiers in Chemistry Pub Date : 2024-09-16 eCollection Date: 2024-01-01 DOI: 10.3389/fchem.2024.1454650

Shaoyan Wang, Thu Ha Tran, Jia Jia, Yuhua Feng

{"title":"A non-classical synthetic strategy for organic mesocrystals.","authors":"Shaoyan Wang, Thu Ha Tran, Jia Jia, Yuhua Feng","doi":"10.3389/fchem.2024.1454650","DOIUrl":"10.3389/fchem.2024.1454650","url":null,"abstract":"Mesocrystals are ordered nanoparticle superstructures, often with internal porosity, which receive much recent research interest in catalysis, energy storage, sensors, and biomedicine area. Understanding the mechanism of synthetic routes is essential for precise control of size and structure that affect the function of mesocrystals. The classical synthetic strategy of mesocrystal was formed via self-assembly of nanoparticles with a faceted inorganic core but a denser (or thicker) shell of organic molecules. However, the potential materials and synthetic handles still need to be explored to meet new applications. In this work, we develop a non-classical synthetic strategy for organic molecules, such as tetrakis (4-hydroxyphenyl) ethylene (TPE-4OH), tetrakis (4-bromophenyl) ethylene (TPE-4Br), and benzopinacole, to produce mesocrystals with composed of microrod arrays via co-solvent-induced crystal transformation. The aligned nanorods are grown epitaxially onto organic microplates, directed by small lattice mismatch between plates and rods. Thus, the present work offers general synthetic handle for establishing well-organized organic mesocrystals.","PeriodicalId":12421,"journal":{"name":"Frontiers in Chemistry","volume":"12 ","pages":"1454650"},"PeriodicalIF":3.8,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0