Food Bioscience最新文献

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Identification and mechanistic characterization of digestion-stable angiotensin-converting enzyme inhibitory peptides from Sophora moorcroftiana seed protein 苦参种子蛋白中消化稳定型血管紧张素转换酶抑制肽的鉴定及机理研究
1区 农林科学
Food Bioscience Pub Date : 2026-03-23 DOI: 10.1016/j.fbio.2026.108724
Xinling Nie, Lu Bai, Lu Hou, Fei Wang, Hao Shi, Xun Li
{"title":"Identification and mechanistic characterization of digestion-stable angiotensin-converting enzyme inhibitory peptides from Sophora moorcroftiana seed protein","authors":"Xinling Nie, Lu Bai, Lu Hou, Fei Wang, Hao Shi, Xun Li","doi":"10.1016/j.fbio.2026.108724","DOIUrl":"https://doi.org/10.1016/j.fbio.2026.108724","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"79 1","pages":"108724-108724"},"PeriodicalIF":0.0,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147879916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioactive constituents from Rhinacanthus nasutus tea ameliorate insulin resistance via modulation of the IRS1/PI3K/Akt/GSK 3β and sphingolipid metabolism pathways 鼻棘茶中的生物活性成分通过调节IRS1/PI3K/Akt/GSK 3β和鞘脂代谢途径改善胰岛素抵抗
1区 农林科学
Food Bioscience Pub Date : 2026-03-05 DOI: 10.1016/j.fbio.2026.108587
Junyu Liu, Xudong Yi, Yiman Yao, Jinrui Zhang, Min Zhang, Pharkphoom Panichayupakaranant, Joseph Buhagiar, Haixia Chen
{"title":"Bioactive constituents from Rhinacanthus nasutus tea ameliorate insulin resistance via modulation of the IRS1/PI3K/Akt/GSK 3β and sphingolipid metabolism pathways","authors":"Junyu Liu, Xudong Yi, Yiman Yao, Jinrui Zhang, Min Zhang, Pharkphoom Panichayupakaranant, Joseph Buhagiar, Haixia Chen","doi":"10.1016/j.fbio.2026.108587","DOIUrl":"https://doi.org/10.1016/j.fbio.2026.108587","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"78 1","pages":"108587-108587"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147879307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using integrated multi-omics and molecular docking to decode stone epiphytic culture as a strategy for enhancing flavonoids and bioactivity in Dendrobium officinale leaves for functional tea development 利用整合多组学和分子对接技术对石斛附生培养进行解码,提高石斛叶片黄酮类化合物和生物活性,开发功能茶
1区 农林科学
Food Bioscience Pub Date : 2026-03-04 DOI: 10.1016/j.fbio.2026.108590
LI Jian-jun, Rong Zhou, S. L. Hu, Y Chen, Shaohao Xie, Jinyu Wu, Jianzhong Chen, Hongbin Hou, Du Guangying
{"title":"Using integrated multi-omics and molecular docking to decode stone epiphytic culture as a strategy for enhancing flavonoids and bioactivity in Dendrobium officinale leaves for functional tea development","authors":"LI Jian-jun, Rong Zhou, S. L. Hu, Y Chen, Shaohao Xie, Jinyu Wu, Jianzhong Chen, Hongbin Hou, Du Guangying","doi":"10.1016/j.fbio.2026.108590","DOIUrl":"https://doi.org/10.1016/j.fbio.2026.108590","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"78 1","pages":"108590-108590"},"PeriodicalIF":0.0,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shaping distinct flavor profiles of barley malt wort through aerobic fermentation with Saccharomyces cerevisiae and Monascus ruber 通过酿酒酵母和红曲霉橡胶有氧发酵形成独特风味的大麦麦芽汁
1区 农林科学
Food Bioscience Pub Date : 2026-03-04 DOI: 10.1016/j.fbio.2026.108594
Yingjie Wu, Yingying Huang, Jialan Zhang, Mengxiang Gao, Suo Chen, Li Li
{"title":"Shaping distinct flavor profiles of barley malt wort through aerobic fermentation with Saccharomyces cerevisiae and Monascus ruber","authors":"Yingjie Wu, Yingying Huang, Jialan Zhang, Mengxiang Gao, Suo Chen, Li Li","doi":"10.1016/j.fbio.2026.108594","DOIUrl":"https://doi.org/10.1016/j.fbio.2026.108594","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"78 1","pages":"108594-108594"},"PeriodicalIF":0.0,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discovery of Pseudomonas iridis HZAU-219 as a potential uricase producer and investigation of its uric acid degradation activity 绿假单胞菌HZAU-219的发现及其尿酸降解活性研究
1区 农林科学
Food Bioscience Pub Date : 2026-03-03 DOI: 10.1016/j.fbio.2026.108589
Mingyu Wu, Chenyu Ding, Jiale Ding, Shufang Guo, Haoyang Xu, Yanchun Huang, Ailing Guo
{"title":"Discovery of Pseudomonas iridis HZAU-219 as a potential uricase producer and investigation of its uric acid degradation activity","authors":"Mingyu Wu, Chenyu Ding, Jiale Ding, Shufang Guo, Haoyang Xu, Yanchun Huang, Ailing Guo","doi":"10.1016/j.fbio.2026.108589","DOIUrl":"https://doi.org/10.1016/j.fbio.2026.108589","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"78 1","pages":"108589-108589"},"PeriodicalIF":0.0,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-enhanced novel fluorescence quencher with internal hollow structure and external polydopamine layer for sensitive detection of chlortetracycline in milk 新型内中空外聚多巴胺层双增强荧光猝灭剂用于牛奶中氯四环素的灵敏检测
IF 5.9 1区 农林科学
Food Bioscience Pub Date : 2026-03-01 Epub Date: 2026-01-23 DOI: 10.1016/j.fbio.2026.108364
Shijin Huang , Ganggang Zhang , Zongyou Chen , Jiawei Chen , Xiaocui Lai , Weihua Lai
{"title":"Dual-enhanced novel fluorescence quencher with internal hollow structure and external polydopamine layer for sensitive detection of chlortetracycline in milk","authors":"Shijin Huang ,&nbsp;Ganggang Zhang ,&nbsp;Zongyou Chen ,&nbsp;Jiawei Chen ,&nbsp;Xiaocui Lai ,&nbsp;Weihua Lai","doi":"10.1016/j.fbio.2026.108364","DOIUrl":"10.1016/j.fbio.2026.108364","url":null,"abstract":"<div><div>Chlortetracycline (CTC), a broad-spectrum veterinary antibiotic, poses serious risks to human health through bioaccumulation due to excessive use. To address the critical need for CTC monitoring, we developed a fluorescence quenching lateral flow immunoassay (FQ-LFIA) employing black bimetallic hollow nanoparticles (BBHNPs) as quencher. BBHNPs were engineered with a unique dual-advantage architecture: an internal hollow structure for enhanced light capture capability and an external polydopamine layer for higher spectral overlap with fluorophores. This design resulted in exceptional photophysical characteristics, including a remarkable molar extinction coefficient (2.18 × 10<sup>12</sup> L mol<sup>−1</sup> cm<sup>−1</sup>) and an unprecedented fluorescence quenching constant (5.20 × 10<sup>13</sup> L mol<sup>−1</sup>). BBHNP-based FQ-LFIA achieved a limit of detection (LOD) of 0.32 ng mL<sup>−1</sup>, representing a 6.91-fold improvement over conventional gold nanoparticle-based lateral flow immunoassay (LFIA). Validation studies in spiked milk samples showed excellent recovery rates (87.73–118.09 %) with high precision (coefficient of variation &lt;10.36 %). Method comparison with liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis confirmed the reliability of BBHNP-FQ-LFIA for real-world applications.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"77 ","pages":"Article 108364"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146075882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality assessment of dealcoholized wines produced by dialysis, osmotic distillation, and hybrid membrane technologies 透析、渗透蒸馏和混合膜技术生产的脱醇葡萄酒的质量评价
IF 5.9 1区 农林科学
Food Bioscience Pub Date : 2026-03-01 Epub Date: 2026-01-20 DOI: 10.1016/j.fbio.2026.108343
Yogesh Kumar , Lorenzo Italiano , Matthias Schmitt , Sayali Bhor , Florian Kiene , Arianna Ricci , Giuseppina Paola Parpinello , Andrea Versari
{"title":"Quality assessment of dealcoholized wines produced by dialysis, osmotic distillation, and hybrid membrane technologies","authors":"Yogesh Kumar ,&nbsp;Lorenzo Italiano ,&nbsp;Matthias Schmitt ,&nbsp;Sayali Bhor ,&nbsp;Florian Kiene ,&nbsp;Arianna Ricci ,&nbsp;Giuseppina Paola Parpinello ,&nbsp;Andrea Versari","doi":"10.1016/j.fbio.2026.108343","DOIUrl":"10.1016/j.fbio.2026.108343","url":null,"abstract":"<div><div>This study investigates dealcoholization approaches, including dialysis (Dia), osmotic distillation (OD), and a hybrid membrane system combining nanofiltration (NF) and OD (NF-OD), for producing dealcoholized white wines (≤0.5 % v/v ethanol) in compliance with regulatory standards. Physicochemical results showed an increase in density for all dealcoholized wines (DWs). OD showed no significant change in the total dry extract, and an increase in acidity and glycerol content compared to the original wine (OW). In contrast, Dia caused significant losses in acidity (−63 %), glycerol (−45 %), and dry extract (−32 %), while NF-OD showed intermediate effects. Minerals were best retained in OD and NF-OD, whereas Dia induced severe depletion (&gt;80 % loss of K, Ca, Mg). Colour parameters for OD/NF-OD remained stable (ΔE &lt; 1), while Dia showed perceptible differences (ΔE = 1.30). GC–MS analysis showed more than a 73 % reduction in volatile compounds in the produced DWs compared to OW, with esters and higher alcohols being the most affected. Sensory evaluation indicated reduced sweetness, hotness and body/fullness in all DWs, but NF-OD preserved acidity, bitterness, and overall acceptability comparable to OW, outperforming OD and Dia. NF-OD emerges as the optimal technique for quality preservation.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"77 ","pages":"Article 108343"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146075883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reformulating savory biscuit-like snacks for a healthier diet by using ancient grain and glasswort powder: effect on quality, sensory descriptors and acceptability 通过使用古老的谷物和玻璃草粉,为更健康的饮食重新制定美味的饼干状零食:对质量,感官描述符和可接受性的影响
IF 5.9 1区 农林科学
Food Bioscience Pub Date : 2026-03-01 Epub Date: 2026-01-24 DOI: 10.1016/j.fbio.2026.108310
Antonio Derossi, Grazia Marinaro, Carmela Lamacchia, Rossella Caporizzi, Giulia Conversa
{"title":"Reformulating savory biscuit-like snacks for a healthier diet by using ancient grain and glasswort powder: effect on quality, sensory descriptors and acceptability","authors":"Antonio Derossi,&nbsp;Grazia Marinaro,&nbsp;Carmela Lamacchia,&nbsp;Rossella Caporizzi,&nbsp;Giulia Conversa","doi":"10.1016/j.fbio.2026.108310","DOIUrl":"10.1016/j.fbio.2026.108310","url":null,"abstract":"<div><div>Aligning with the growing demand for salt reduction strategies and the need to protect food biodiversity, this study aims to develop healthy savory biscuit-like snacks with reduced sodium content. An ancient (Automonia B) and modern (Bolero) soft wheat variety were combined with various concentrations of salt (0 %, 1 %, 2 %) and glasswort powder (1 %, 4 %, and 8 %).</div><div>Physical and microstructural analysis revealed that Bolero samples exhibited significantly higher hardness values (76.88 ± 15.4 N) compared to Autonomia B (54.5 ± 11.5 N). However, hardness decreased in both varieties as the concentration of glasswort increased, reaching average values of 67.17 ± 5 N for Bolero and 41.6 ± 3.5 N for Autonomia B. The total porosity of Bolero snacks was lower compared to Autonomia B, but other microstructural attributes, e.g. structure thickness and separation, were closely linked to textural properties. Salt and glasswort concentrations significantly influenced the sensory properties of biscuits formulated with two wheat varieties, while visual attributes remained consistently acceptable. Saltiness perception was mainly driven by salt but was also significantly enhanced by glasswort, supporting its role as a natural <em>“green salt”</em> ingredient. Overall taste showed a non-linear response, with moderate salt and glasswort levels maximizing pleasantness. These results highlight glasswort as a promising strategy for sodium reduction without compromising sensory quality, offering an innovative, scalable and biodiversity-enhancing strategy solution for industry-driven salt-reduction programs.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"77 ","pages":"Article 108310"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146075887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterologous expression of phospholipase A1 gene in PichiaPink™ and optimization of catalytic conditions for phospholipid ω-3 fatty acid synthesis 磷脂酶A1基因在PichiaPink™中的异源表达及磷脂ω-3脂肪酸合成催化条件的优化
IF 5.9 1区 农林科学
Food Bioscience Pub Date : 2026-03-01 Epub Date: 2026-01-21 DOI: 10.1016/j.fbio.2026.108344
Mingwei Liu , Ke Zhao , Shufan Liu , Yaoheng Cui , Qing Kong , Dongxing Yu , Yunxiao Ma
{"title":"Heterologous expression of phospholipase A1 gene in PichiaPink™ and optimization of catalytic conditions for phospholipid ω-3 fatty acid synthesis","authors":"Mingwei Liu ,&nbsp;Ke Zhao ,&nbsp;Shufan Liu ,&nbsp;Yaoheng Cui ,&nbsp;Qing Kong ,&nbsp;Dongxing Yu ,&nbsp;Yunxiao Ma","doi":"10.1016/j.fbio.2026.108344","DOIUrl":"10.1016/j.fbio.2026.108344","url":null,"abstract":"<div><div>In this study, a highly efficient and stable phospholipase A<sub>1</sub> (PLA<sub>1</sub>) gene was cloned from <em>Aspergillus oryzae</em> and heterologously expressed in PichiaPink™. The optimized PLA<sub>1</sub> achieved a maximum enzyme activity of 26.42 ± 0.38 U/mL, designated as <em>P1pink</em>. Through scale-up cultivation in a 50 L fermenter, the PLA<sub>1</sub> activity reached 114.30 ± 1.41 U/mL, representing the highest reported activity of PLA<sub>1</sub> in the <em>Pichia</em> expression system. Using fatty acids from fish oil and phosphatidylcholine (PC) from soybeans as substrates, immobilized PLA<sub>1</sub> catalyzed transesterification to successfully synthesize PC containing ω-3 polyunsaturated fatty acids (PUFAs). Detailed investigations on immobilization were conducted, with 724 resin selected as the carrier; the enzyme activity of PLA<sub>1</sub> more than doubled after immobilization. Through transesterification modification of PC, key reaction parameters were optimized to determine the optimal conditions: a substrate mass ratio of 1:5, enzyme addition of 25 %, reaction temperature of 60 °C, water addition of 0.75 %, and reaction time of 32 h. Under these conditions, the total incorporation rate of docosahexaenoic acid/eicosapentaenoic acid (DHA/EPA) reached 22.77 ± 0.62 %. Additionally, the immobilized PLA<sub>1</sub> exhibited excellent reusability, retaining over 50 % of its initial activity after four repeated uses.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"77 ","pages":"Article 108344"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146026247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polydatin in rheumatological diseases: Multitarget mechanisms and therapeutic potential 多聚糖在风湿病中的作用:多靶点机制和治疗潜力
IF 5.9 1区 农林科学
Food Bioscience Pub Date : 2026-03-01 Epub Date: 2026-02-09 DOI: 10.1016/j.fbio.2026.108453
Chiara Baggio , Paolo Sfriso , Amelia Carmela Damasco , Giacomo Cozzi , Giampietro Ravagnan , Roberta Ramonda , Francesca Oliviero
{"title":"Polydatin in rheumatological diseases: Multitarget mechanisms and therapeutic potential","authors":"Chiara Baggio ,&nbsp;Paolo Sfriso ,&nbsp;Amelia Carmela Damasco ,&nbsp;Giacomo Cozzi ,&nbsp;Giampietro Ravagnan ,&nbsp;Roberta Ramonda ,&nbsp;Francesca Oliviero","doi":"10.1016/j.fbio.2026.108453","DOIUrl":"10.1016/j.fbio.2026.108453","url":null,"abstract":"<div><div>Rheumatological diseases encompass a wide range of conditions primarily affecting the musculoskeletal system. They represent a significant burden on modern society, affecting millions of people worldwide. These chronic and debilitating conditions require long-term management and a multidisciplinary approach that combines pharmacological interventions with lifestyle modifications for optimal patient outcomes. In this context, diet is emerging as a crucial support in managing rheumatological diseases. Certain dietary patterns and specific nutrients can play a significant role in reducing inflammation, alleviating symptoms, and potentially slowing disease progression. Bioactive compounds, which are found in many plant-based foods and are abundant in the Mediterranean diet, are increasingly being recognized as valuable supports to traditional treatments in arthritis. Among them, polydatin has shown potent antioxidant and anti-inflammatory properties.</div><div>This review aims to comprehensively examine the therapeutic potential of polydatin in various rheumatological diseases, including rheumatoid arthritis, osteoarthritis, crystal-induced arthritis, spondyloarthritis, and systemic lupus erythematosus. Articles included have been identified using keyword-based searches in multiple scientific databases, including PubMed and Scopus.</div><div>The review highlights polydatin's multi-targeted mechanisms, including antioxidant activity, modulation of inflammatory pathways, regulation of apoptosis and autophagy, and direct interactions with molecular targets like sirtuin 1 and chemokine receptor type 1. Although clinical studies specifically investigating polydatin in rheumatological conditions are scarce, the translational potential of this compound is supported by randomized controlled trials involving other human inflammatory and pain-related disorders. Polydatin's favorable pharmacokinetic profile, enhanced bioavailability, and diverse biological actions position it as a promising natural compound for managing rheumatological diseases.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"77 ","pages":"Article 108453"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147399022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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