Food BiosciencePub Date : 2025-04-18DOI: 10.1016/j.fbio.2025.106640
Akib Ali , Pankaj Bharali
{"title":"The rise of plant-based meat alternatives: Challenges and perspectives","authors":"Akib Ali , Pankaj Bharali","doi":"10.1016/j.fbio.2025.106640","DOIUrl":"10.1016/j.fbio.2025.106640","url":null,"abstract":"<div><div>As we navigate the complexities of a rapidly changing food landscape, plant-based meat alternatives offer a compelling vision of a more sustainable, ethical, and inclusive future. From reducing our environmental footprint and promoting animal welfare to improving public health and fostering culinary innovation, the rise of plant-based meats represents a transformative shift in how we nourish ourselves and our planet. Consumption of Plant based meat products also aligns with sustainable developments goals (SDG 2, 3, 12, 13 & 15). Therefore, continued innovation, collaboration, and conscious consumption can leverage these alternatives to build a resilient and equitable food system for future generations. Despite their rapid growth, the plant-based meat industry faces both challenges and opportunities. The hypothetical question raised about its nutritive value continues to be a topic of debate. In view to that, this comprehensive review emphasized into the plant-based industry's evolution, explores its key drivers, assesses its environmental and ethical impacts, and evaluates its future potential.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106640"},"PeriodicalIF":4.8,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143864806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epigenetic regulation on fungal disease affecting plant-based food: A review from the perspectives of host, pathogen and their interactions","authors":"Yanling Ren , Linyan Feng , Xin Xu , Jianbo Xiao , Yueming Jiang , Taotao Li","doi":"10.1016/j.fbio.2025.106633","DOIUrl":"10.1016/j.fbio.2025.106633","url":null,"abstract":"<div><div>Fungal diseases of plant-based food cause substantial loss in food availability and financial profits as well as security concern. It is absolutely imperative to understand the pathogenesis and manage fungal diseases of crop plants. In recent years, increasing body of evidence showed that epigenetic regulation acts a key role in modulating plant immune responses during fungal infection on plant hosts. We reviewed current progress on epigenetic regulation mechanisms underlying fungal infection and offered an in-depth view of how epigenetic regulation efficiently manipulated plant immune responses. We mainly focused on the role of DNA methylation, histone modification, chromatin structures, and non-coding RNAs in fungal pathogenicity. In detail, the roles of these epigenetic modifications in plant response to fungal infection, fungal virulence on plant hosts, and effector-mediated phytopathogenic fungus-host interactions were summarized. These epigenetic modifications provided a dynamic and reversible mechanism for pathogens to adapt to host environments and evade plant defenses. Based on the knowledge of how fungal effectors subvert plant host immunity or defense system through epigenetic regulation, the possible application of epigenetic mechanism-based disease management strategies was proposed, including artificial intelligence based methods. Further investigation on necrotic effectors and their host targets will expand our knowledge of fungal pathogenesis as well as plant resistance. In addition, we highlighted the possible role of effectors in the complex interactions between plant immunity, microbial pathogenesis, and the environment, with the goal of designing adaptation strategies in dynamically changing environments.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106633"},"PeriodicalIF":4.8,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food BiosciencePub Date : 2025-04-17DOI: 10.1016/j.fbio.2025.106624
Mohamed E. Abd El-Hack , Ahmed A. Allam , Ahmed K. Aldhalmi , Mahmoud Kamal , Muhammad Arif , Abdullah S. Alawam , Hassan A. Rudayni , Ayman E. Taha , Elwy A. Ashour , Mohammad M.H. Khan
{"title":"Nutritional value and therapeutic applications of Chenopodium album for human and livestock health: A comprehensive review","authors":"Mohamed E. Abd El-Hack , Ahmed A. Allam , Ahmed K. Aldhalmi , Mahmoud Kamal , Muhammad Arif , Abdullah S. Alawam , Hassan A. Rudayni , Ayman E. Taha , Elwy A. Ashour , Mohammad M.H. Khan","doi":"10.1016/j.fbio.2025.106624","DOIUrl":"10.1016/j.fbio.2025.106624","url":null,"abstract":"<div><div><em>Chenopodium album</em>, commonly known as lamb's quarters or wild spinach, has long been recognized as a nutrient-dense plant, yet its applications in human and livestock nutrition and pharmaceutical sciences remain significantly underexplored. This article presents a novel perspective on the epigenetic, microbiome-modulating, metabolic-enhancing, and therapeutic roles of <em>Chenopodium album</em>. By leveraging its bioactive phytochemicals, high nutrient density, and adaptive growth properties, this research highlights how the <em>Chenopodium album</em> can be integrated into precision human diets, sustainable livestock feeding strategies, and pharmaceutical formulations to enhance health, immunity, and productivity. We propose a cutting-edge framework for its use in functional foods, livestock dietary supplementation, and drug development, setting the stage for a new era in nutrition and medicine.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106624"},"PeriodicalIF":4.8,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food BiosciencePub Date : 2025-04-16DOI: 10.1016/j.fbio.2025.106626
Guangdong Yang , Xiaoxiao Qin , Jing Ma , Zhong Zhang , Jizhuang Wang , Xingbin Yang
{"title":"Micro/nanomotors: A novel platform for food safety detection and auxiliary processing","authors":"Guangdong Yang , Xiaoxiao Qin , Jing Ma , Zhong Zhang , Jizhuang Wang , Xingbin Yang","doi":"10.1016/j.fbio.2025.106626","DOIUrl":"10.1016/j.fbio.2025.106626","url":null,"abstract":"<div><div>Micro/nanomotors, as dynamic micro/nano carriers, enhance reaction rates, reduce costs, and enable multifunctional tasks through functionalization. As alternatives to traditional detection and processing methods, a variety of functionalized MNMs have been developed, with preliminary applications explored in food safety detection and auxiliary processing. This review summarizes the propulsion mechanisms of MNMs tailored for food matrices, covering chemical-fueled propulsion (e.g., water, acid, H<sub>2</sub>O<sub>2</sub>, glucose) and external-field-controlled propulsion (e.g., magnetic, light, ultrasonic). It highlights the strengths and limitations of MNMs in food safety detection (e.g., pathogens, toxins, heavy metals) and auxiliary processing (e.g., sterilization, allergen removal, water purification), emphasizing their high reaction efficiency and recyclability. However, challenges such as scalable and low-cost preparation, intelligent control, and biocompatibility must be addressed to advance practical applications. Future research should focus on homogenized fabrication techniques, multifunctional integration, and expanding MNMs' roles in nutrient delivery and real-time monitoring. Addressing these gaps will unlock their full potential in revolutionizing food safety and industrial processing, paving the way for sustainable and intelligent food systems.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106626"},"PeriodicalIF":4.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in structure and function of non-heme proteins in food stuffs: A promising dietary iron source for human health","authors":"Yilin Xing , Xuetong Wang , Selenge Erdenechimeg , Qiuhong Liao , Jiachen Zang","doi":"10.1016/j.fbio.2025.106621","DOIUrl":"10.1016/j.fbio.2025.106621","url":null,"abstract":"<div><div>Non-heme proteins, particularly transferrins, ferritins, and iron-sulfur proteins, play essential roles in iron metabolism and have promising applications in dietary supplementation, functional foods, and medical applications. These proteins regulate iron through diverse mechanisms such as chelation, mineralization, and redox cycling, enabling controlled transport, release, and storage. Compared to conventional ferrous salts, non-heme proteins offer a safer and more effective approach to iron supplementation. However, the absorption and bioavailability of non-heme iron remain influenced by external factors, including pH variations, redox conditions, and dietary inhibitors such as phytates and polyphenols. This review explores recent advancements in their structural properties, functional roles, and emerging applications, with a focus on strategies to enhance dietary iron absorption and stability during food processing. Additionally, current challenges in their food and pharmaceutical applications are discussed, along with bioengineering strategies to improve their functionality.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106621"},"PeriodicalIF":4.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food BiosciencePub Date : 2025-04-11DOI: 10.1016/j.fbio.2025.106434
Juan Li , Zhaozhan Liu , Yan Du , Zhiming Zhong , Zhaoxin Tu , Wenju Zhou , Zhengxing Chen , Li Wang , Xinxia Zhang , Ting Li
{"title":"Highland barley functional tea extract alleviates alcoholic liver disease by modulating gut microbiota and reducing hepatic oxidative stress and inflammation in mice","authors":"Juan Li , Zhaozhan Liu , Yan Du , Zhiming Zhong , Zhaoxin Tu , Wenju Zhou , Zhengxing Chen , Li Wang , Xinxia Zhang , Ting Li","doi":"10.1016/j.fbio.2025.106434","DOIUrl":"10.1016/j.fbio.2025.106434","url":null,"abstract":"<div><div>Alcoholic liver injury is a prevalent health issue worldwide, characterized by oxidative stress, inflammation, and gut microbiota imbalance. Traditional treatments often focus on reducing alcohol intake and managing symptoms, but novel therapeutic approaches targeting gut microbiota and oxidative stress are gaining attention. Highland barley functional tea (HBFT) extract was known for its antioxidant and anti-inflammatory properties, but its effects on alcoholic liver injury and gut microbiota remained unclear. This study aimed to evaluate the protective effects of HBFT on alcoholic liver injury and elucidated its underlying mechanisms of action. Male C57BL/6 J mice were divided into six groups (n = 12): control, model (0.2 mL/20 g per day), positive drug (0.2 mL/20 g per day), low-dose HBFT (1.4 g/kg per day), medium-dose HBFT (2.8 g/kg per day), and high-dose HBFT (5.6 g/kg per day). The findings indicated that HBFT intervention significantly inhibited the increase in ALT and AST serum levels. HBFT also enhanced the activity of enzymes and expression of proteins associated with oxidative stress, inflammatory damage, and hepatic lipid metabolism. Furthermore, HBFT promoted the proliferation of beneficial gut bacteria in mice, such as Akkermansia and Lactobacillus. Moreover, the HBFT intervention helped restore the levels of short-chain fatty acids (SCFAs) in mice caused by alcohol exposure. Taken together, these results suggested that HBFT extract may act as a novel gut microbiota modulator, alleviating alcoholic liver injury by restoring gut microbial balance and ameliorating hepatic oxidative stress and inflammation.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106434"},"PeriodicalIF":4.8,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food BiosciencePub Date : 2025-04-10DOI: 10.1016/j.fbio.2025.106584
Yaya Yang , Shunli Jing , Le Zhang , Jiali Shao , Jixuan Chen , Guohua Xia , Huan Yang , Cunshan Zhou
{"title":"Structure, function, synthesis and improved strategies of fucosylated human milk oligosaccharides and their future perspectives: A review","authors":"Yaya Yang , Shunli Jing , Le Zhang , Jiali Shao , Jixuan Chen , Guohua Xia , Huan Yang , Cunshan Zhou","doi":"10.1016/j.fbio.2025.106584","DOIUrl":"10.1016/j.fbio.2025.106584","url":null,"abstract":"<div><div>Human milk oligosaccharides (HMOs) are a diverse group of lactose-derived carbohydrates and represent the third most abundant component in human milk. Fucosylated HMOs, which are particularly abundant, offer significant benefits to infants and have garnered increasing interest in recent decades. However, their widespread application in the food industry and other sectors remains limited due to challenges associated with their synthesis and isolation on a large scale. This review summarizes the chemical structures of fucosylated HMOs and their biological functions, critically evaluates conventional and cutting-edge synthetic strategies, and discusses the major challenges and future prospects in this field. Despite advancements, our understanding of the bioactivities and functions of fucosylated HMOs remains limited, necessitating further <em>in vitro</em> and <em>in vivo</em> studies. Fucosidase-catalyzed transfucosylation and metabolic engineering have emerged as promising strategies for their synthesis. Additionally, plant-based synthesis offers a sustainable alternative for large-scale production. Genetic modification, reaction condition optimization, and protein engineering have significantly improved the production of fucosylated HMOs. However, challenges such as identifying economical substrates, obtaining enzyme crystal structures for molecular engineering, developing advanced purification techniques, and ensuring the safety of synthesized products remain. Systematic evaluation and integration of knowledge are essential to drive progress in this field.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106584"},"PeriodicalIF":4.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food BiosciencePub Date : 2025-04-10DOI: 10.1016/j.fbio.2025.106571
Izamara de Oliveira , Celestino Santos-Buelga , Yara Aquino , Lillian Barros , Sandrina A. Heleno
{"title":"New frontiers in the exploration of phenolic compounds and other bioactives as natural preservatives","authors":"Izamara de Oliveira , Celestino Santos-Buelga , Yara Aquino , Lillian Barros , Sandrina A. Heleno","doi":"10.1016/j.fbio.2025.106571","DOIUrl":"10.1016/j.fbio.2025.106571","url":null,"abstract":"<div><div>Phenolic compounds are secondary metabolites widely distributed in the plant kingdom, valued for their strong antioxidant and antimicrobial properties. These bioactive compounds are promising natural alternatives to artificial preservatives in the food industry, aligning with consumer demand for sustainable solutions that ensure food quality and safety. In this review, the structural complexity of bioactive phenolic compounds, which include their various subclasses and the chemical basis of their antioxidant and antimicrobial activity, is explored. This review examines innovative extraction methods designed to preserve the bioactivity of these compounds. Additionally, it examines their incorporation as natural preservatives, focusing on stability issues and applications in the food sector. The structural diversity of phenolic compounds underpins their broad applications in food preservation. These include antimicrobial and antioxidant properties, which contribute to food safety and offer potential health benefits. The use of agro-industrial biowastes as a sustainable supply of phenolics is a promising approach; however, standardization is necessary to obtain extracts with consistent and effective biological activity. Innovative techniques, such as encapsulation and integration into edible films, are being developed to improve the stability and effectiveness of these compounds, expanding their application in various food products.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106571"},"PeriodicalIF":4.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Species identification in meat products using quantitative and qualitative PCR techniques, with emphasis on chicken detection","authors":"Zahra Sarlak , Nayebali Rezvani , Ehsan Parandi , Nasrin Karami , Maryam Azizi-Lalabadi , Milad Rouhi","doi":"10.1016/j.fbio.2025.106568","DOIUrl":"10.1016/j.fbio.2025.106568","url":null,"abstract":"<div><div>Undeclared adulteration of chicken in processed meat products is commonly reported because of easier and cheaper access. As a result, authenticating techniques should be applied to evaluate their existence in these products. The DNA's higher stability during processing than lipids and proteins makes DNA-based techniques ideal for meat authenticity and traceability. Among these, polymerase chain reaction (PCR) techniques are reliable, highly sensitive, and specific for detecting species origin in foodstuffs. DNA-based methods are divided into two categories including qualitative (species-specific PCR, PCR-RFLP, and DNA barcoding) and quantitative (real-time PCR, droplet-digital PCR, and next-generation sequencing-based DNA metabarcoding) assays. Therefore, the present review intends to critically investigate the principles, advantages, challenges, and advances of PCR techniques, and their practicality for the detection of undeclared chicken in meat products. Among qualitative PCR techniques, capillary and microchip electrophoresis assays could simultaneously detect the animal species with a lower limit of detection than traditional gel electrophoresis. Nevertheless, the detection of undeclared species may occur due to accidental cross-contamination with minute quantities of various meat species during food processing. Quantitative PCR methods, on the other hand, are capable of distinguishing between deliberate and unintentional mislabeling. Additionally, despite the higher cost, NGS-assisted DNA sequencing surpasses other species authentication methods as it can quantitatively identify all target and non-target species using high-quality barcode sequence reference databases. This review could act as a reference guide for researchers, DNA-based technique developers, and regulatory authorities seeking to enhance the global standard protocol for chicken identification in meat products through PCR methodologies.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106568"},"PeriodicalIF":4.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143817033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in CRISPR/Cas9-driven strategies for microbial production and optimization of sugar polyols for food applications: A review","authors":"Manoj Kumar , Sumit Totade , Kanika Sharma , Ajinath Dukare , K. Pandiyan , Sujata Saxena","doi":"10.1016/j.fbio.2025.106553","DOIUrl":"10.1016/j.fbio.2025.106553","url":null,"abstract":"<div><div>Sugar polyols, including xylitol, erythritol, mannitol and sorbitol are vital nutritional sweeteners having significant applications across various sectors like food, pharmaceuticals, and cosmetics. Metabolic engineering in microbes is a center of attraction to produce value-added products from the lignocellulosic biomass. Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 has emerged as a powerful and transformative platform in molecular biology, offering innovative solutions for enhancing the biosynthesis of sugar polyols, paving the way for more efficient and cost-effective production methods. This review aims to offer a thorough overview of CRISPR/Cas9 technology and its role in enhancing production of sugar polyols in microbial systems. It focuses on recent advancements and optimization strategies for improving polyol biosynthesis and productivity through CRISPR/Cas9 based gene editing and fermentation process optimization. The review highlights several successful implementations of CRISPR/Cas9 technology in modifying biosynthetic pathways for sugar polyol production in microbes. Continued research and development in this area are likely to lead to further improvements in efficiency and scalability, benefiting various industries particularly food and pharmaceutical industry that rely on these valuable compounds.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"68 ","pages":"Article 106553"},"PeriodicalIF":4.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}