Food Bioscience最新文献

{"title":"Electron beam and X-ray irradiation promote extraction of bioactive compounds from walnut green husk: Structural, physicochemical, and functional properties","authors":"Ruolin Wang, Heyu Shen, Anwei Luo","doi":"10.1016/j.fbio.2024.104739","DOIUrl":"https://doi.org/10.1016/j.fbio.2024.104739","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142007775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and in silico screening of novel angiotensin-converting enzyme inhibitory peptides from pacific saury: Interaction mechanism, network pharmacology, stability, Caco-2 monolayer transport","authors":"Shu Wang, Hui Wang, Zongcai Tu","doi":"10.1016/j.fbio.2024.104576","DOIUrl":"https://doi.org/10.1016/j.fbio.2024.104576","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142014089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pasting, rheology, structural properties and in vitro digestibility of potato starch complexes co-gelatinized with squash polysaccharides","authors":"Yu Zhang, Bingjie Yang, Jing Zhao","doi":"10.1016/j.fbio.2024.104932","DOIUrl":"https://doi.org/10.1016/j.fbio.2024.104932","url":null,"abstract":"","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viola stocksii: A rich source of antioxidant and anti-inflammatory flavonoid glycosides with converged therapeutic potential against SARS-CoV-2 MPro, spike trimer, and surface glycoproteins","authors":"","doi":"10.1016/j.fbio.2024.105095","DOIUrl":"10.1016/j.fbio.2024.105095","url":null,"abstract":"<div><p>This research presents the first comprehensive investigation into the phytochemical and nutraceutical properties of <em>Viola stocksii.</em> The study aimed to identify the therapeutic efficacy and bioactive constituents of this medicinal herb, traditionally used as an herbal tea for managing respiratory and abdominal issues in remote areas of Pakistan. The therapeutic efficacy of the plant was assessed as an anti-oxidant-rich health tonic coupled with anti-inflammatory and immunomodulatory activities against COVID-19 and its evolving variants. The study involved sequential extraction, bio-assay guided fractionation, isolation, characterization, and biological evaluation. Preliminary <em>in vitro</em> studies have demonstrated that polar fractions of the plant possess significant antioxidant and antiinflammatory potential. A diverse combination of chromatographic techniques (Diaion resin HP-20, Sephadex LH-20, ODS-C18, and RP-HPLC) facilitated the purification of active constituents of the plant. Comprehensive analysis of NMR (¹H, ¹³C, and 2D NMR) and mass (EIMS, HR-EIMS, and FAB-HRMS) spectral data lead to characterize the isolated compounds (<strong>1</strong>–<strong>4</strong>) as flavonoid glycosides. Results from <em>in vitro</em> and <em>in-silico</em> evaluations revealed that the isolated glycosides exhibit high antioxidant, antiinflammatory, and immunomodulatory activities, which synergistically show promising potential in combating SARS-CoV-2 variants. Besides M^Pro, therapeutic potential against two unexplored proteins i.e. the spike trimer (7WZ1) and surface glycoproteins (7QTJ) was studied for the first time. Kaempferol (<strong>KamGluαRh</strong>) and quercetin (<strong>QurGluαRh</strong>) carrying rutinoside, were identified as the most active constituents of the plant, with the highest binding affinities in the range of −10 to −13 kcal/mol. Ten distinct active regions were explored on the spike trimer, including strong binding affinity with the essential RBD region, spike head, and tail of the protein. MD simulation validated the stability of <strong>M</strong>^{<strong>pro</strong>}-<strong>KamGluαRh</strong> and <strong>M</strong>^{<strong>pro</strong>}<strong>-QurGluαRh</strong> complexes evidenced by an average RMSD of 0.2 nm led to the mechanistic understanding of M^pro inhibition. ADMET and pharmacokinetic studies authenticated the therapeutic ability and drug-likeness profiling of all extracted compounds. Results revealed the beneficial role of glycosides in boosting the medicinal effectiveness of flavonoids and the potential of <em>Viola stocksii</em> as an immunity booster against respiratory infections like COVID-19.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212429224015256/pdfft?md5=0677c54d568d48c4bdc8a7af9f9c2dfa&pid=1-s2.0-S2212429224015256-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142232208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the potential susceptibility of planktonic cells and bacterial biofilms by diosgenin","authors":"","doi":"10.1016/j.fbio.2024.105106","DOIUrl":"10.1016/j.fbio.2024.105106","url":null,"abstract":"<div><p>Bacterial biofilms are formed by a complex community of microorganisms, held together by a matrix that provides structural support and stability to microbial communities, making infections associated with biofilms more difficult to treat. In the face of growing research in the health area in search of antibiotics with action against biofilms, natural products present an effective alternative strategy. In this context, the aim of this study was to evaluate bacterial biofilm formation, assess the susceptibility of planktonic cells to diosgenin, and examine its efficacy on inhibiting and treating biofilms. The broth microdilution method was used to determine the Minimum Inhibitory Concentration (MIC). Six bacterial strains were tested: <em>Staphylococcus aureus</em> ATCC 25923, <em>Pseudomonas aeruginosa</em> ATCC 9027, <em>Pseudomonas aeruginosa</em> 24, <em>Enterococcus faecalis</em> INCQS 0017, <em>Enterococcus faecalis</em> INCQS 00018, and <em>Enterococcus faecalis</em> INCQS 654. The crystal violet method was employed to evaluate the potential of diosgenin in biofilm inhibition and eradication. Chlorhexidine gluconate served as a reference standard for the antibiofilm assays, along with the antibiotics norfloxacin, ampicillin, and gentamicin. MIC determination revealed that diosgenin exhibited intrinsic antimicrobial activity, with an MIC of 406 μg/mL against <em>S. aureus</em> ATCC 25923. The antibiofilm activity showed significant inhibition for <em>E. faecalis</em> 17 and moderate inhibition against <em>E. faecalis</em> 654 and <em>S. aureus</em> 25923. Furthermore, diosgenin effectively eradicated preformed biofilms of <em>S. aureus</em> 25923 and <em>P. aeruginosa</em> 9027, indicating its ability to interfere with biofilm biomass. These results suggest that diosgenin not only inhibits bacterial biofilm formation but also eradicates established biofilms, highlighting it as a promising candidate for the development of products aimed at combating bacterial biofilms.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The combination of oxalic acid and uric acid degrading probiotic from traditional Chinese fermented food reduces calcium accumulation and prevents kidney stones formation in rats","authors":"","doi":"10.1016/j.fbio.2024.105099","DOIUrl":"10.1016/j.fbio.2024.105099","url":null,"abstract":"<div><p>Kidney stones, often resulting from a complex interplay of factors including oxalic acid, uric acid, and calcium. Current treatments lack comprehensive consideration of these factors and come with side effects. In this study, <em>Lactobacillus paracasei</em> GR-10 and <em>Pediococcus acidilactici</em> GR-11 were isolated from the fermented food “Jiangshui”. GR-10 demonstrated the ability to degrade 62.70% of oxalic acid (10 mM) within 24 h, while GR-11 degraded 28.60% of uric acid (4 mM). Combined treatment with GR-10 and GR-11 significantly reduced the number of stones in rats with ethylene glycol-induced kidney stones. This reduction was accompanied by a 57.19% decrease in urinary oxalate and a 52.80% decrease in serum uric acid levels. Simultaneously, urinary calcium level decreased by 27.18%. Inflammatory markers and indicators of oxidative stress associated with kidney stones were restored. Furthermore, the combined treatment effectively regulated the microbiota imbalance induced by kidney stones, resulting in reduced purine nucleoside accumulation in rat feces. This study offers promising insights into probiotics as an adjunct therapy for the prevention of kidney stones in the future.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142232207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acesulfame potassium induces hepatic inflammation and fatty acids accumulation via disturbance of carnitine metabolism and gut microbiota","authors":"","doi":"10.1016/j.fbio.2024.105101","DOIUrl":"10.1016/j.fbio.2024.105101","url":null,"abstract":"<div><p>The controversy surrounding the impact of acesulfame potassium (Ace-K) on metabolic health has been growing. Here, male C57BL/6 mice were given Ace-K for 11 weeks (sterile water as the control group, 40 mg/kg body weight as the low dose group, 120 mg/kg as the high dose group), subsequently gut microbiome and targeted metabolomics were conducted to evaluate the effect of Ace-K on host health. Gut microbiota was perturbed by Ace-K, as evidenced by the down-regulation of beneficial bacteria and the increased abundance of <em>Collinsella</em> associated with inflammation. Fatty acids metabolism was altered by Ace-K, as evidenced by elevated long chain fatty acids (LCFAs) in liver and serum. Notably, the reduction of related genes and proteins correlated to carnitine metabolism and hepatic carnitine metabolites by Ace-K led to a reduction in the <em>β</em>-oxidation of LCFAs, ultimately causing the accumulation of LCFAs. These findings uncovered new perspectives on Ace-K-induced hepatic inflammation and fatty acids accumulation.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extraction of apple pomace polyphenols using natural deep eutectic solvents: A sustainable approach","authors":"","doi":"10.1016/j.fbio.2024.105083","DOIUrl":"10.1016/j.fbio.2024.105083","url":null,"abstract":"<div><p>To effectively utilize apple pomace resources, we extracted apple pomace polyphenols using natural deep eutectic solvent (NADES) as the medium, with a solvent-to-solid ratio of 50 mL/g, for a duration of 120 min. Compared to conventional extraction solvents (ethanol and methanol), four NADES significantly enhanced the extraction efficiency of polyphenols from apple pomace. Notably, NADES 1 (betaine: urea = 1:1, 30% water) and NADES 2 (betaine: malic acid = 1:1, 30% water) exhibited superior extraction capabilities, with maximum values reaching 5.245 ± 0.124 mg GAE/g pomace and 5.157 ± 0.164 mg GAE/g pomace, respectively, in Qinguan apple pomace. Both solvents reached their maximum extraction efficiency within 120 min, with NADES 1 achieving a maximum extraction amount of 4.8325 mg GAE/g and NADES 2 achieving 5.3039 mg GAE/g from Fuji apple pomace. NADES 1 and NADES 2 were more efficient in extracting monophenols such as quercetin, rutin, gallic acid, and procyanidin, whereas organic solvents (methanol and ethanol) were more effective for monophenols like methyl gallate and phlorizin. Furthermore, polyphenol extracts obtained using NADES from Fuji apple pomace displayed varying levels of antibacterial effectiveness, with NADES 4 (glucose: lactic acid = 1:5, 60% water) and NADES 2 showing superior efficacy against <em>Escherichia coli</em> and <em>Staphylococcus aureus</em>. This comprehensive study not only demonstrated the potential of NADES in extracting polyphenols from apple pomace but also highlighted their applicability as natural preservatives in the food industry.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142172420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intelligent quality control of gelatinous polysaccharide-based fresh products during cold chain logistics: A review","authors":"","doi":"10.1016/j.fbio.2024.105081","DOIUrl":"10.1016/j.fbio.2024.105081","url":null,"abstract":"<div><p>Gelatinous polysaccharide-based fresh products are influenced by environmental and temperature changes, and maintaining their quality and freshness has always been a challenge. Intelligent management and control of cold chain logistics systems have been extensively used in transporting and storing these goods to overcome the problem. This review introduces common quality deterioration issues, including those encountered during the transportation and storage of these products, such as softening, water loss, and color changes. The application of intelligent detection technologies, including gas detection, intelligent label, and spectral detection is reviewed to achieve real-time monitoring and evaluation of product status. This article also introduces the Internet of Things, wireless sensor networks, and radio frequency identification for product data transmission. It utilizes artificial neural networks and digital twins to build quality models, achieving better management of gelatinous polysaccharide-based fresh products in the cold chain. Moreover, some preservation techniques are used to increase the longevity of these products in storage and reduce losses in the cold chain. These techniques include irradiation, chemical treatment, and coating preservation. This review will, hopefully, encourage additional work that may help reach the goal of having better intelligent quality control of gelatinous polysaccharide-based fresh products during cold chain logistics.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142167857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating transcriptomics and metabolomics differences offers insights into the mechanisms of muscular fat deposition in common carp (Cyprinus carpio)","authors":"","doi":"10.1016/j.fbio.2024.105082","DOIUrl":"10.1016/j.fbio.2024.105082","url":null,"abstract":"<div><p>With the global population increasing and lifestyle improving, the demand for high-quality nutritional aquatic foods has been rising. Muscle fat is a crucial nutritional index for evaluating the quality of fish flesh. However, the comprehensive and systematic understanding of the molecular mechanism underlying differences in muscle fat deposition remains insufficient. In this study, we integrated transcriptomics and metabolomics of selected samples with extremely high and low muscle fat in common carp (<em>Cyprinus carpio</em>), the major freshwater aquaculture fish in Asia, to identify critical genes, metabolites and metabolic pathways. We totally identified 204 differentially expressed genes (DEGs) and 1528 differentially accumulated metabolites (DAMs). Glycerolipid, glycerophospholipid and glyoxylate and dicarboxylate metabolisms were enriched through both transcriptomics and metabolomics. These lipid metabolism pathways may be regulated by some critical signal transduction pathways, including Extracellular matrix [ECM]-receptor interaction, mTOR signaling pathway and FoxO signaling pathway. Combined with the validation of gene expression and biochemical indices, a supposed regulatory network was established. To our knowledge, it is the first study to apply a multi-omics approach in fish with naturally different muscle fat to comprehensively elucidate the mechanism. This study could deepen our understanding of the molecular mechanism of muscle fat deposition and be helpful for improving the quality of fish.</p></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142233894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}