Foodborne pathogens and disease最新文献

{"title":"Prevalence and Antimicrobial Susceptibility Patterns of <i>Salmonella enterica</i> Serovars Along the Dairy Value Chain: A One Health-Relevant Surveillance of Dairy Farms.","authors":"Javed Ahamad Khan, Iqbal Ahmad, Fahad S Bazaid, Fohad Mabood Husain, Leena A Neyaz, Hussein H Abulreesh","doi":"10.1177/15353141261466779","DOIUrl":"https://doi.org/10.1177/15353141261466779","url":null,"abstract":"<p><p>Raw milk is highly prone to microbial contamination and can carry <i>Salmonella enterica</i> serovars-like zoonotic pathogens. This study follows the One Health-informed framework to investigate the occurrence and potential contamination pathways of <i>Salmonella enterica</i> serovars along the raw milk value chain in Bareilly, Uttar Pradesh, Northern India. A total of 900 samples consisted of raw milk (150), milk bucket swabs (150), milkers' hand swabs (150), and farm floor swabs (150) collected from one local dairy farm, and one institutional dairy farm, and one retail milk outlet over a 6-months period. Overall, 19 samples (2%) were <i>Salmonella enterica</i> serovars positive, where pathogen occurrence was noted as 4.7% in farm floor swabs, 4.7% in milking bucket swabs, and 2% in raw milk. <i>Salmonella enterica</i> serovars was not detected in udder swabs, towel swabs, and milker hand swabs. Antimicrobial susceptibility analysis demonstrated high <i>Salmonella enterica</i> serovars (<i>n</i> = 19) resistance to ampicillin (73.7%) and tetracycline (68.4%), whereas multiple isolates (48%) exhibited multidrug resistance as well. These findings necessitate upgraded dairy hygiene practices, controlled antimicrobial use in veterinary medicine, and integrated One Health-relevant surveillance to mitigate raw milk consumption-associated public health risks in the studied region.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"15353141261466779"},"PeriodicalIF":2.3,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148367640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Biocides in Eliminating Biofilms of <i>Enterobacteriaceae</i>, Lactic Acid Bacteria, and Spoilage Microorganisms Isolated from Meat Fabrication Equipment.","authors":"Cheyenne C Conrad, Yadav Barun, Tim McAllister, Xianqin Yang","doi":"10.1177/15353141261464411","DOIUrl":"https://doi.org/10.1177/15353141261464411","url":null,"abstract":"<p><p>The study aimed to evaluate the effectiveness of two cleaners (Tergazyme and PowerFoam Plus) and two sanitizers (Decon 7 and BioDestroy) against biofilms formed by a variety of bacterial species obtained from meat processing plants (<i>n</i> = 44). Biofilms were developed on polystyrene pegs at alternating temperatures of 8°C for 16 h, followed by 15°C for 8 h, over a duration of 6 days. Bacteria within biofilms were enumerated by plating, and biomass was quantified by crystal violet staining and measuring absorbance (<i>A</i>₅₇₀). Thirty of the 44 meat plant bacterial strains formed measurable biofilms, of which 43% (<i>n</i> = 19) were weak biofilm formers, 9% (<i>n</i> = 4) were moderate biofilm formers, and 16% (<i>n</i> = 7) were strong biofilm formers. Of the two sanitizers, Decon 7 was the most effective at biofilm eradication (100%). The effectiveness of BioDestroy for biofilm removal was improved by a pretreatment step of PowerFoam Plus and Tergazyme. These findings show that pretreatment with cleaning products is important for improving the effectiveness of some sanitizers, and soaking equipment with cleaners prior to application of sanitizers may improve biofilm removal in meat processing environments.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"15353141261464411"},"PeriodicalIF":2.3,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148367628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Houseflies as Vectors of ESBL-Producing Enterobacterales: Insights from Hospital Settings in a Low- to Middle-Income Country.","authors":"Noah Obeng-Nkrumah, Paul Kwao, Enid Owusu, Gloria Della Tawiah-Abrokwa, Jerry Dzidzornu-Gomez, David Baidoo, Francisca Nana Afua Duah, Sarah Saidu, Appiah-Korang Labi","doi":"10.1089/fpd.2024.0099","DOIUrl":"10.1089/fpd.2024.0099","url":null,"abstract":"<p><p>The spread of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) in communities has been facilitated by direct contact with humans or animal carriers and insects such as houseflies. Houseflies may have an increased risk of human exposure to antimicrobial-resistant pathogens, including ESBL-E. In this study, we determined the presence of ESBL-E in houseflies and ready-to-eat food samples from selected food vending sites in five health care facilities in Greater Accra, Ghana. Sixty (60) food vending sites were included in this study. Flies (10) were pooled, and food (5 g) was macerated and homogenized aseptically in brain-heart infusion agar. Suspensions were cultured on MacConkey agar supplemented with 4 µg/mL cefotaxime for ∼18 h. Phenotypic and molecular characterization of ESBL-E was performed using a combination disk diffusion method, multiplex polymerase chain reaction, and direct nucleotide sequencing. Of the 60 food vending sites, 62% (37) of the food vendors had flies within their premises that carried ESBL-E, and 15% (9) of the food samples collected from the vendors were contaminated with ESBL-E. The most predominant ESBL-producing Enterobacterales from housefly samples was <i>Proteus vulgaris</i> (54%) and that of food samples were <i>P. vulgaris</i> (22.5%) and <i>Escherichia coli</i> (22.5%). All Enterobacterales from flies and food samples harbored an ESBL gene with <i>bla_CTX-M</i>, mostly <i>bla_CTX-M-15</i>, being the predominant gene and gene type, respectively. Houseflies may be potential contributors to the spread of ESBL-producing Enterobacterales in Ghana.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"451-459"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobiota and Their Mycotoxins in Egyptian Dried Figs.","authors":"Helal F Al-Harthi, Hanan AlOmari, Ioan Pet, Youssuf A Gherbawy","doi":"10.1089/fpd.2025.0048","DOIUrl":"10.1089/fpd.2025.0048","url":null,"abstract":"<p><p>This study evaluates the impact of traditional sun drying and modern industrial drying techniques on fungal contamination and mycotoxin production in dried figs. A total of 80 samples (40 per drying method), collected from various retail sources in Upper Egypt, were analyzed. Fungal isolation was performed on Dichloran Rose Bengal Chloramphenicol agar medium and incubated at 28°C. Sun-dried figs exhibited significantly higher fungal loads (1395 colony-forming unit [CFU]/g) compared with industrially dried figs (750 CFU/g). Mycobiota analysis identified 33 fungal species across 12 genera in sun-dried figs, whereas industrial drying yielded 21 species. Internal transcribed spacer sequencing facilitated species identification, with accession numbers PV065865 to PV065896 deposited in GenBank. <i>Aspergillus</i> spp. were dominant in both drying methods, with <i>Aspergillus welwitschiae</i>, <i>A. flavus</i>, and <i>A. niger</i> being the most prevalent. Mycotoxin analysis revealed aflatoxin contamination in 37.5% of sun-dried and 15% of industrially dried figs, while ochratoxin A was detected in 57.5% and 27.5% of samples, respectively, for sun-dried and industrially dried figs. Total fumonisins were present in 12.5% of sun-dried and 5% of industrially dried figs. These findings highlight the efficacy of industrial drying techniques in mitigating fungal contamination and mycotoxin accumulation, thereby improving the microbiological safety of dried figs.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"482-493"},"PeriodicalIF":2.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controlling the Storage Time Is an Effective Measure to Reduce the Risk of Bongkrekic Acid Poisoning Caused by Wet Rice Noodles.","authors":"Zhiting Liu, Can Liu, Hongsheng Chen, Zihui Chen, Panpan Huang, Jiewen Peng, Jian Sun, Jianjun Zhao, Jian Wen, Junhua Liang, Manting Weng, Haiming Guo, Ping Gan, Qiong Huang","doi":"10.1089/fpd.2024.0131","DOIUrl":"10.1089/fpd.2024.0131","url":null,"abstract":"<p><p>In October 2018, bongkrekic acid (BKA) poisoning cases caused by consuming wet rice noodles contaminated with <i>Burkholderia gladioli</i> were first reported in Guangdong Province, resulting in three cases, and two of them died. Due to the high fatality rate, the Guangdong Health Commission issued a code. The core risk-control elements of the code were storage temperature and storage time management, and the storage time is controlled through adopting a small sealed package with a clearly labeled production date and shelf life. In this study, we followed up on the code's implementation and compared the incidence of related foodborne diseases before and after the implementation of the code. Due to the rarity of <i>B. gladioli</i> contamination, monitoring its prevalence directly was challenging. Therefore, we also assessed the levels of <i>B. cereus</i>, a more common foodborne pathogen in wet rice noodles, to infer trends in microbial contamination. Then the feasible and effective measures to control BKA poisoning caused by wet rice noodles were analyzed. A questionnaire survey revealed that the implementation rate of packaging management-utilizing complete independent small sealed package with clearly marked shelf life to control storage duration-reached 81.25%. However, the adoption rate of cold storage management was only 41.96%. The annual average number of BKA poisoning cases in Guangdong Province dropped from 6.25 before implementing the code to 0.5 after implementing the code. The detection rate of <i>B. gladioli</i> and <i>B. cereus</i> in the samples decreased from 1.56% (1/64) to 0.45% (1/220) and 42.26% (71/168) to 5% (11/220), respectively. The reduction of <i>B. gladioli</i> and <i>B. cereus</i> may reflect the improvement in microbial status. This study indicated that although the storage temperature control was not ideal, controlling the storage time through adopting a complete independent small sealed package with a clearly marked shelf life could still effectively mitigate BKA poisoning caused by wet rice noodles.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"468-472"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted Antimicrobial Resistance Gene Screening from Metagenomic DNA of Raw Milk Samples Identifies the Presence of Multiple Genes Including the <i>mcr9</i>.","authors":"Remina M Shajahan, Athul M, Farhana T A, Sreejith Sreekumaran, Divya Lakshmanan, Mithilesh Jaiswal, Radhakrishnan E K","doi":"10.1089/fpd.2024.0187","DOIUrl":"10.1089/fpd.2024.0187","url":null,"abstract":"<p><p>The current study has investigated the prevalence of antimicrobial resistance (AMR) genes in cow and goat raw milk samples. The misuse of antibiotics in the livestock sector has already been reported to be a major factor contributing to AMR risk. For the study, milk samples were collected from five different farms, and metagenomic DNA was extracted. Then, PCR amplification was carried out using primers specific to 15 different AMR genes. From the results obtained, the prevalence of β-lactam resistance genes, particularly <i>blaTEM</i> (24%), along with other genes like <i>blaZ</i> (12%) and <i>blaSHV</i> (8%), were observed in addition to the transmissible <i>mcr9</i> gene (12%) conferring resistance to colistin. These findings underscore the urgent need for monitoring AMR genes and regulating antibiotic use in dairy farming to safeguard public health, as it poses a potential risk with the consumption of unpasteurized milk.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"494-496"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomics Revealed Novel Chromosomal Integration of Antimicrobial Resistance Cluster <i>tet</i>(B), <i>sul</i>2, <i>bla</i>_TEM-1B, <i>aph(3″)</i>-Ib, and <i>aph(6)</i>-Id in <i>Salmonella</i> Typhimurium.","authors":"Zengfeng Zhang, Mengjun Hu, Kannappan Arunachalam, Chunlei Shi","doi":"10.1089/fpd.2024.0172","DOIUrl":"10.1089/fpd.2024.0172","url":null,"abstract":"<p><p>Antimicrobial-resistant <i>Salmonella</i> has posed a huge threat to food safety and public health, and tetracycline is the commonly used antibiotic for treating salmonellosis. In this study, eight <i>Salmonella</i> Typhimurium isolates from diarrhea patients (<i>n</i> = 7) and clam (<i>n</i> = 1) exhibited high-level tetracycline resistance (minimum inhibitory concentration = 128 μg/mL), and these isolates were further resistant to ampicillin and sulfonamides, formatting the R-type ASuT (ampicillin, sulfonamides, and tetracycline). Then, these eight isolates were sequenced using PacBio platform, revealing the presence of tetracycline resistance gene <i>tet</i>(B), along with sulfonamide-resistance gene <i>sul</i>2, extended-spectrum-β-lactamase gene <i>bla</i>_TEM-1B, and aminoglycoside resistance genes <i>aph(3″)</i>-Ib and <i>aph(6)</i>-Id on the chromosome, which was associated with R-type ASuT. Four types (A, B1, B2, and C) of genetic arrangement for chromosomally encoding <i>tet</i>(B) were found, inserted into <i>flj</i>BA operon. Type C (<i>flj</i>BA operon-<i>tet</i>(B)-<i>sul</i>2-<i>bla</i>_TEM-1B-<i>aph(3″)</i>-Ib-<i>aph(6)</i>-Id-<i>mer</i>ACDEPTR) was the most common type and was accompanied by various insertion sequences (ISs) (IS<i>26</i>, IS<i>1</i>, and IS<i>Vsa5</i>) and recombinases. Pairwise sequence alignment showed that type C arrangement likely resulted from stepwise acquisitions and rearrangements facilitated by the actions of ISs, followed by integration into the chromosome by prophages. Phylogenomic analysis showed that all eight <i>Salmonella</i> Typhimurium isolates from China in this study, along with a human-borne <i>Salmonella</i> Typhimurium isolate (DA34821) from Germany and a foodborne <i>Salmonella</i> Typhimurium isolate (CFSA629) from China, clustered into a single clade, sharing ≤67 SNPs, which suggested that clone spread occurred. These findings underline the emergence of R-type ASuT in <i>Salmonella</i> Typhimurium, which is attributed to the presence of an antimicrobial resistance gene cluster (<i>tet</i>(B), <i>sul</i>2, <i>bla</i>_TEM-1B, <i>aph(3″)</i>-Ib, and <i>aph(6)</i>-Id) encoded on the chromosome.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"441-450"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Identification, Antibiotic Resistance, Virulence Characteristics, and Genome Analysis of <i>Cronobacter</i> spp. Isolated from Infant Rice Cereal in Nanchang, China.","authors":"Rui Li, Huifen Jiang, Xiaosi Wang, Pingping Zhai, Xin Wu, Jiajun Wei","doi":"10.1089/fpd.2025.0002","DOIUrl":"10.1089/fpd.2025.0002","url":null,"abstract":"<p><p><i>Cronobacter</i> spp. are well known to be resistant to osmotic and dry stresses and can persist in a variety of foods. <i>C. sakazakii</i> and <i>C. malonaticus</i> are currently considered to be the primary pathogenic species that cause severe diseases. There are few studies on the prevalence of <i>Cronobacter</i> spp. in infant rice cereal. Information on the diversity, pathogenicity, and virulence of <i>Cronobacter</i> species obtained from foods is still relatively scarce and fragmentary. In this article, a total of 67 <i>Cronobacter</i> spp. strains were isolated from infant rice cereal in Nanchang, China. Forty-seven strains of <i>C. sakazakii</i> and 11 strains of <i>C. malonaticus</i> were identified by polymerase chain reaction (PCR). The resistance to 10 antibiotics was analyzed, showing that all isolates were sensitive except two strains. PCR detection for the five virulence genes (<i>cpa</i>, <i>aut</i>, <i>hly</i>, <i>inv</i>, and <i>sip</i>) and whole genome sequencing were performed. Co-existence of CSA or CMA with <i>ampH</i> was found in <i>C. sakazakii</i> and <i>C. malonaticus</i> strains. Compared with <i>C. sakazakii</i>, <i>C. malonaticus</i> lacked various virulence genes including <i>yeeJ</i>, <i>stjC</i>, and <i>nanAKT</i> genes. Another important observation was the presence of <i>csg</i> in the <i>C. malonaticus</i> genomes, while it was not found in the <i>C. sakazakii.</i> Notably, STs 1, 7, and 4, which are frequently associated with clinical infections, were observed. <i>C. sakazakii</i> and <i>C. malonaticus</i> strains induced higher apoptosis rate in Caco-2 cell in comparison with other <i>Cronobacter</i> species.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"460-467"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Helminthic Parasites in Slaughtered Small Ruminants in Qazvin Province, Iran: Implications for One Health and the Food Industry.","authors":"Mohammadreza Mohammadi, Fariba Najar Hoseini, Giovanni Sgroi, Saeed Bahadory, Kareem Hatam-Nahavandi, Meysam Olfatifar, Ali Asghari, Mohsen Imandar, Amir Javadi, Oskar Nowak, Aida Vafae Eslahi, Milad Badri","doi":"10.1089/fpd.2025.0040","DOIUrl":"10.1089/fpd.2025.0040","url":null,"abstract":"<p><p>Helminthic parasites are a significant concern for the food industry because of their detrimental effects on livestock health and food safety. This study aimed to provide data on the prevalence of helminthic parasites in 2250 slaughtered small ruminants in Qazvin Province, Iran. The overall infection rate was 56.6%, with sheep (64.9%) exhibiting a higher prevalence compared with goats (41.9%). Cystic echinococcosis (CE) was the most frequently detected parasite, followed by <i>Moniezia expansa</i> and <i>Cysticercus tenuicollis</i>. This study revealed higher susceptibility to infections in male animals and younger sheep, with infections occurring year-round, peaking in spring and summer. These findings highlight the need for targeted interventions, such as improved pasture management and deworming strategies, to mitigate economic losses and zoonotic risks. This research contributes significantly to livestock health and food safety efforts in Iran, advocating for integrated control measures within a One Health framework.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"473-481"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the Dual Role of <i>Campylobacter jejuni:</i> From Pathogen to Potential Tumorigenesis Catalyst.","authors":"Amina Zergui, Mohamed Merzoug, Choubaila Leksir, Yamina Merzouk, Hanane Fatma Chentouf, Imane Djaballi","doi":"10.1089/fpd.2025.0003","DOIUrl":"10.1089/fpd.2025.0003","url":null,"abstract":"<p><p><i>Campylobacter jejuni</i> is widely recognized as a leading cause of bacterial gastroenteritis worldwide. While its acute effects on human health are well documented, a growing body of research suggests that its impact extends far beyond transient infections. Emerging evidence indicates that <i>C. jejuni</i> may contribute to chronic inflammatory conditions and even tumorigenesis, particularly within the gastrointestinal tract. However, the potential role of this pathogen in cancer development remains underexplored, leaving a critical gap in the current literature. This review aims to bridge this gap by providing a comprehensive analysis of <i>C. jejuni</i>'s dual role as both a foodborne pathogen and a potential catalyst for long-term disease. We examine its transmission pathways, unique virulence factors, and evolving antimicrobial resistance patterns, highlighting their implications for public health. More importantly, we explore recent findings that suggest a mechanistic link between persistent <i>C. jejuni</i> infection, chronic inflammation, and carcinogenesis, focusing on its ability to induce deoxyribonucleic acid damage and immune evasion. By synthesizing insights from microbiology, epidemiology, and clinical research, this review offers a novel perspective on <i>C. jejuni</i>, shifting the focus beyond its acute pathogenicity to its broader health implications. In doing so, it underscores the urgent need for further studies to elucidate its oncogenic potential and inform new strategies for prevention and intervention. This review not only advances our understanding of <i>C. jejuni</i>'s impact on human health but also calls attention to a pressing yet overlooked research frontier in infectious disease and cancer biology.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":"431-440"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}