Foodborne pathogens and disease最新文献

{"title":"Experience and Perspectives on Antibacterial Therapy for Listeriosis in a Tertiary Teaching Hospital in China: A Retrospective Study and Health Care Provider Survey.","authors":"Naiju Zhang, Zhenjie Wang, Zhijun Li, Yongzhong Xie, Jinchun Liu, Chunming Gao, Chuanmiao Liu, Tianping Chen","doi":"10.1089/fpd.2024.0079","DOIUrl":"https://doi.org/10.1089/fpd.2024.0079","url":null,"abstract":"<p><p>Listeriosis is a rare, life-threatening bacterial infection. Prompt, appropriate antibiotic treatment is essential to save lives. We aimed to investigate antibiotic selection and listeriosis knowledge among health care providers. We first performed a retrospective study on patients with listeriosis who were treated in a hospital in China from January 2013 to March 2023. Patient characteristics and antibiotic selections were recorded. Antibiotics were classified as effective or ineffective based on the efficacy classifications listed in <i>The Sanford Guide to Antimicrobial Therapy</i> (50^th edition). We then conducted a questionnaire survey of health care providers to investigate their listeriosis knowledge and practices between April 2023 to May 2023. Fifteen listeriosis patients were identified, with a case fatality rate of 26.7% (4/15). Empirical treatments assessed as effective antibiotics or ineffective antibiotics were given to 33.3% (5/15) and 66.7% (10/15) of the patients, respectively. After <i>Listeria monocytogenes</i> was identified, 40% (6/15) of the patients received an adjustment to their antibiotics, although 50% (3/6) patients still received ineffective antibiotics. The questionnaire survey of 77 participating health care providers showed that 32.9% (24/73) of the clinicians were unaware of the appropriate antibiotics for listeriosis. Most participants (83.1%, 64/77) would read the drug sensitivity report before selecting the antibiotics. The selection of effective antibiotics differed between the infectious diseases department and other departments (<i>p</i> < 0.001), but did not differ between junior title and other titles (<i>p</i> = 0.088). Most patients with listeriosis did not receive appropriate antibiotics, which might have accounted for the high fatality rate, and may have resulted from inadequate listeriosis knowledge. More education and correct reporting of drug sensitivity results are urgently needed.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Listeriosis Case Associated with Ice Cream Consumption in China in 2019.","authors":"Xiaoyuan Zhang, Yanlin Niu, Yuzhu Liu, Penghang Zhang, Xiaochen Ma","doi":"10.1089/fpd.2024.0009","DOIUrl":"https://doi.org/10.1089/fpd.2024.0009","url":null,"abstract":"<p><p>During the 2019 Chinese National Microbiological Food Safety Surveillance program, <i>Listeria monocytogenes</i> was detected in ice cream samples produced by Manufacturer A. By comparing the sequences of isolates derived from the ice cream with those of isolates derived from humans, we identified one human-derived isolate that was genetically indistinguishable from one ice cream-derived isolates. The patient was hospitalized with listeriosis in Beijing, China in March 2019. Food history obtained from the patient indicated that he had consumed ice cream produced by Manufacturer A during the 30-day period before the onset of illness. No cases of listeriosis were detected after the ice cream produced by Manufacturer A was removed from the shelves. Overall, this report presents the first case of <i>L. monocytogenes</i> infection associated with ice cream in China.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morbidity, Mortality, and Epidemiological Features of Clinical Invasive Listeriosis Isolates from Sentinel Surveillance in Beijing, China, 2013-2022.","authors":"Tongyu Wang, Yanlin Niu, Jinru Jiang, Xiaoyuan Zhang, Chao Wang, Yangbo Wu, Yunchang Guo, Weiwei Li, Penghang Zhang, Yuzhu Liu, Linlin Wang, Xiaochen Ma","doi":"10.1089/fpd.2024.0067","DOIUrl":"https://doi.org/10.1089/fpd.2024.0067","url":null,"abstract":"<p><p>Listeriosis is a relatively rare but severe foodborne disease, which has significant public health concern of persons with underlying conditions and pregnant women. This study aimed to estimate the morbidity, mortality, and fatality rates of listeriosis over a 10-year period and clarify the epidemiological features of the pathogen in Beijing, China, based on voluntary reporting of sentinel surveillance. A total of 228 listeriosis cases were reported with annual morbidity rate of 1.054 per million inhabitants, including 113 maternal-neonatal cases with mean annual morbidity rate of 63.401 per million live births in Beijing from 2013 to 2022.The morbidity rate increased from 0.094 to 0.868 per million inhabitants from 2013 to 2019 (<i>p</i> for trend = 0.003). The overall and maternal-neonatal fatality rate were 31.82% and 42.86%, respectively. Four serogroups were identified in this study, and 1/2b predominated (89 strains). We observed the morbidity rate of listeriosis increased in Beijing over the past 10 years. Maternal-neonatal cases accounted for a higher proportion than that described in other countries, considering population base and fertility policy in China, official recommendations targeting pregnant women should be actively promoted.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142947054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Virulence Gene and Drug Resistance Analysis of Shiga Toxin-Producing <i>Escherichia coli</i> from Diarrhea Calves in Xinjiang, China.","authors":"Lei Wang, Yixin Bai, Xuhui Shi, Xiaofeng Zheng, Yingyu Liu, Yi Zhang, Mengfei Zhang, Zhanqiang Su, Jinxin Xie, Panpan Tong","doi":"10.1089/fpd.2024.0056","DOIUrl":"https://doi.org/10.1089/fpd.2024.0056","url":null,"abstract":"<p><p>This investigation aimed to examine the virulence genes and antimicrobial resistance profiles of Shiga toxin-producing <i>Escherichia coli</i> (STEC) strains found in diarrheal calves in Xinjiang between 2016 and 2022. A total of 800 samples, including 232 fecal and 568 rectal swabs from calves under 2 months old with diarrhea, were analyzed for Shiga toxin (Stx)-encoding genes using polymerase chain reaction. The study characterized the isolates based on their <i>stx</i> subtypes, virulence genes, O serogroups, phylogenetic groups, hemolytic phenotypes, antibiotic resistance, and resistance genes. This investigation detected 32 STEC isolates, with <i>stx1</i> and <i>stx2</i> genes in 37.5% and 12.5% of the isolates, respectively. Additionally, half of the isolates contained both genes. The combination of <i>stx</i> subtypes was predominantly observed as follows: <i>stx1a/stx2d</i> (31.3%), <i>stx1a</i> only (31.3%), <i>stx1a/stx2a/stx2d</i> (12.5%), <i>stx2d</i> only (9.4%), <i>stx1a/stx1d/stx2d</i> (6.2%), <i>stx1a/stx1d</i> (6.2%), and <i>stx2a/stx2d</i> (3.1%). The <i>eae</i> gene was found in one isolate that carried <i>stx1</i>, <i>stx2</i>, and <i>hlyA</i>, defining it as enterohemorrhagic <i>E. coli</i>. Additionally, six STEC carrying the <i>astA</i> gene were identified as EAST1⁺ STEC. These isolates did not correspond to the serotypes in the \"top seven\" category. The phylogenetic analysis revealed that most strains belonged to groups B1 (43.8%) and A (40.6%), with 56.3% exhibiting hemolytic activity. Moreover, among the 34.4% resistant isolates (2021∼2022), the drug resistance rates of STEC isolates to tetracycline, florfenicol, ceftazidime, ampicillin, cefotaxime, gentamicin, and sulphamethoxazole ranged from 21.9% to 34.4%, to streptomycin, piperacillin, ceftazidime, aztreonam-polymyxin B, and cefepime ranged from 3.1% to 18.8%. All isolates exhibited multiple drug resistance. The most common resistance genes identified were <i>floR</i> (31.3%), <i>tetA</i> (25.0%), <i>sulR</i> (15.6%), <i>strA</i> and <i>strB</i> (12.5%), and <i>bla</i>_CTX-M-1, <i>bla</i>_TEM-1, and <i>mph</i>(A) (9.4%). These findings offer valuable information that might aid in developing preventative measures and enhance the comprehension of the epidemiological characteristics of STEC in calves.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whole-Genome Sequencing of Antimicrobial Resistant <i>Klebsiella quasipneumoniae</i>, a Novel Sequence Type 5655 from Retail Fish Market, Assam, India.","authors":"Sahadevan Sangeetha, Sudha Sajeev, Muneeb K Hamza, Bibek R Shome, Claire Raisen, Mark A Holmes, Gopalan Krishnan Sivaraman","doi":"10.1089/fpd.2023.0017","DOIUrl":"https://doi.org/10.1089/fpd.2023.0017","url":null,"abstract":"<p><p><i>Klebsiella quasipneumoniae</i> is a recently described species that can be differentiated from <i>Klebsiella pneumoniae</i>. However, in clinical settings, they are frequently misidentified as <i>K. pneumoniae</i>. In this study, our objective was to conduct genomic characterization and bioinformatics analysis of <i>K. quasipneumoniae</i> subsp. <i>quasipneumoniae</i> (KpII-A) isolated from a sample obtained from a retail fish market in Assam, India. Notably, this particular isolate was identified as <i>K. pneumoniae</i> when identified using BD Pheonix™ M50 (BD Difco, USA). This represents a serious pitfall of conventional microbiological methods for distinguishing between <i>K. pneumoniae</i> and <i>K. quasipneumoniae</i>. In this connection, identifying differences in nuclear gene content is key to avoid misidentification. The isolate was confirmed to be KpII-A using species identification by Mash Screen and whole-genome sequencing by the Illumina platform. We report the draft genome sequence of this strain, comprising of 53 contigs with an average GC content of 58.11%. The annotation revealed 5,095 protein coding sequences, 69 tRNA genes, and 4 rRNA genes. The isolated strain acknowledges the presence of <i>oqxA, oqxB, fosA,</i> and <i>bla</i>_OKP-A-3 antimicrobial resistance genes (ARGs). Additionally two phage genomes were detected in contigs 3 and 19 of the bacterial genome. Based on the multilocus sequence typing and genome sequencing, the isolate was identified as a novel sequence type, ST5655, within the species <i>K. quasipneumoniae</i> under the phylogroup KpII-A. The presence of antimicrobial resistance genes in KpII-A, isolated from retail fish samples, raises concerns regarding transmission across barriers in ecological niches and possible transmission to consumers. Given that fish may serve as a potential vehicle for ARG transmission, our findings are highly relevant and paramount to human health. Moreover, our study supports the robustness of the sequence-based microbial identification.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Listeria monocytogenes, Salmonella</i> spp., and <i>Staphylococcus aureus:</i> Threats to the Food Industry and Public Health.","authors":"Vinicius B Mantovam, David F Dos Santos, Luis C Giola Junior, Mariza Landgraf, Uelinton M Pinto, Svetoslav D Todorov","doi":"10.1089/fpd.2024.0124","DOIUrl":"https://doi.org/10.1089/fpd.2024.0124","url":null,"abstract":"<p><p>Foodborne pathogens have always been of public health concern and represent safety issues for food processors. These pathogens develop new ways to overcome antibiotics, survive in different environmental conditions, and the ability to reproduce in many hostile environments configure them as serious health hazards. Considering the huge number of microorganisms, three bacterial representatives were selected to provide a better knowledge about the question of which one is the worst enemy for humans, from the food industry point of view, taking into consideration their multiplication specificity, virulence, and resistance. As we constantly are exposed to these pathogens in our nutritional habits, this overview aims to summarize the most relevant characteristics associated with the pathogenicity, clinical symptoms and most importantly, how deadly <i>Listeria monocytogenes</i>, <i>Salmonella</i> spp., and <i>Staphylococcus aureus</i> can be in the hospital and the food industry, by comparing among them. Overall, the microbiological knowledge clearly suggests that while all three pathogens are dangerous, <i>L. monocytogenes</i> presents the highest risk of death due to their ability to cause severe complications in vulnerable populations as it presents a range of virulence factors that facilitate evasion of the immune system and cytological effects. Additionally, it shows great resistance to standard food processing and preservation techniques, making it one of the most difficult pathogens to control. Understanding the risks and characteristics of these foodborne pathogens is essential for implementing effective control measures to prevent their occurrence in food products and to promote public health.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serogroups and Toxin Variants of Clinical Shiga Toxin-Producing <i>Escherichia coli</i> Strains Isolated from Patients with Hemolytic Uremic Syndrome in Turkey.","authors":"Elif Okumuş, Aynur Karadenizli, Elif Bahat Özdoğan, Kenan Bek","doi":"10.1089/fpd.2024.0140","DOIUrl":"https://doi.org/10.1089/fpd.2024.0140","url":null,"abstract":"<p><p>Shiga toxin-producing <i>Escherichia coli</i> (STEC) refers to a group of bacteria that can cause infections, which are common worldwide and pose a serious public health problem, as they can lead to conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS). HUS is a disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. Determination of serogroups and toxin profiles of STEC is important for estimating their disease-causing potential and predicting epidemiological changes. This study analyzed STEC isolates from 46 pediatric HUS patients across Turkey, using polymerase chain reaction to determine O serogroups and Shiga toxin (Stx) variants from stool samples collected between 2016 and 2019. Of the patients, 25 (54.3%) were in the 0-2 age group. Of the isolates, 82.6% were non-O157 serogroup. The most detected serogroup was O145 (32.6%), and 28.3% of the serogroups were not typed. Of the strains, 8 (17.4%) had Stx1 alone, 26 (56.5%) had Stx2 alone, and 12 (26.1%) had both Stx1 and Stx2. The Stx variants occurred in seven combinations, with the most common being Stx2a alone (56.5%). The duration of hospitalization for patients with Stx2a was found to be longer than that for patients with other variants (<i>p</i> = 0.01). This study highlights a concerning trend in Turkey, where non-O157 serogroups, particularly O145, emerged as prevalent causes of HUS. The predominance of Stx2a among our isolates and the longer hospitalization duration for patients with Stx2a support findings linking this variant to severe clinical outcomes, including HUS. Understanding the dynamics of these Stx variants will help better prepare for and mitigate the impacts of STEC infections in our population.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142893212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Immunization of Mice with a Nonantibiotic Recombinant <i>Lactobacillus plantarum</i> Coexpressing <i>Trichinella spiralis</i> TsNd and gp43 Protein Vaccine Combined with a Murine Interleukin-33 Adjuvant.","authors":"Hong-Ye Li, Dan Wang, Qiu-Yu Xie, Xin Liu, Jun-Yi Li, Hai-Bin Huang, Nan Wang, Chun-Wei Shi, Tian-Xu Pan, Ming-Han Li, Dong-Yu Zhao, Shu-Yuan Yu, Jia-Yao Guan, Gui-Lian Yang","doi":"10.1089/fpd.2024.0125","DOIUrl":"https://doi.org/10.1089/fpd.2024.0125","url":null,"abstract":"<p><p>Trichinellosis, a zoonotic disease transmitted through food and caused by <i>Trichinella spiralis</i>, is a significant health concern worldwide. Therefore, developing a safe and effective vaccine to combat <i>T. spiralis</i> infection is essential. In this study, a nonantibiotic <i>Lactobacillus plantarum</i> strain lacking the <i>alr</i> gene served as a live bacterial vector to deliver antigens to the host, creating a novel oral vaccine. A nonantibiotic vaccine was constructed to coexpress <i>T. spiralis</i> Nudix hydrolase (TsNd protein) and the gp43 protein alongside a food-grade murine IL-33 adjuvant. The objective of this study was to evaluate the efficacy of this novel strategy in preventing trichinellosis and mitigating intestinal damage. The integrated vaccination strategy was found to increase specific serum immunoglobulin G and mucosal secretory IgA (sIgA) concentration in BALB/c mice. Additionally, this approach significantly increased the release of cytokines such as interleukin-4 (IL-4) from lymphocytes, along with increased CD4⁺ expression on lymph cells from both splenic and mesenteric sources. Post-larval exposure, significant reductions in the populations of adult worms by 59.80% at 7 d postinfection (dpi) and in the larval load by 51.29% at 28 dpi were documented. Furthermore, oral vaccination reduced the number of encysted larvae present in the tongue and masseter muscles after challenge with <i>T. spiralis</i>. Overall, the results demonstrated that combined vaccination with the IL-33 adjuvant effectively prevented trichinellosis and reduced intestinal damage, highlighting the potential of food-grade <i>Lactobacillus</i> vaccines in preventing intestinal parasitic infections, with IL-33 serving as an effective adjuvant.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142881475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic Comparison of Reoccurring, Emerging, and Persistent (REP) Shiga Toxin-Producing <i>Escherichia coli</i> O157:H7.","authors":"Yishan Yang, Xianghe Yan, Bradd J Haley, Charles Li, Xiangwu Nou","doi":"10.1089/fpd.2024.0144","DOIUrl":"https://doi.org/10.1089/fpd.2024.0144","url":null,"abstract":"<p><p><i>Escherichia coli</i> O157:H7 strains associated with several recent (2017-2020) multi-state outbreaks linked to leafy green vegetables have been characterized as \"reoccurring, emerging, and persistent\" (REP). Our recent unpublished work demonstrated that the REP strains had significantly enhanced potential for biofilm formation. In this study, comparative genomic analyses were conducted for a better understanding of the mechanisms behind the enhanced biofilm formation, and thereby potentially increased environmental fitness, by the REP strains. Phylogenetically, the recent outbreak strains formed two distinct clusters represented by REPEXH01 and REPEXH02. Compared with EDL933 and other previous outbreak reference strains, the REP strains (clustering with REPEXH02) exhibiting strong biofilm formation were found to have acquired two genes encoding proteins of unknown functions (hypothetical proteins) and lost certain prophage-related genes. In addition, several single nucleotide polymorphisms in genes related to biofilm formation were identified.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Meta-Analysis of the Detection of Shiga Toxin-Producing <i>Escherichia coli</i> in Cattle in China in the Past 10 Years.","authors":"Baili Zheng, Yaling Cheng, Lan Ma, Yvxuan Cai, Yongchao Li, Yingyu Liu","doi":"10.1089/fpd.2024.0120","DOIUrl":"https://doi.org/10.1089/fpd.2024.0120","url":null,"abstract":"<p><p>Shiga toxin-producing <i>Escherichia coli</i> (STEC) is a significant pathogen that can cause foodborne illnesses and pose a serious public health problem. To date, no systematic evaluation or meta-analysis of STEC carriage in Chinese cattle has been conducted. Therefore, we conducted a systematic review and meta-analysis to assess the prevalence of STEC in cattle in China over the past decade. We retrieved 1868 articles from 6 databases (PubMed, Web of Science, CNKI, Wanfang, VIP, and Baidu). Based on criteria such as sample source, isolation time, and species, we selected 39 studies (comprising 16,437 samples from 14 provinces) for systematic review and meta-analysis. The analysis results indicated that the pooled prevalence of <i>E. coli</i> in cattle during the selected time period was 6% (95% CI: 0.03-0.09). Subgroup analysis revealed variations in STEC positivity rates across different sectors. The highest positivity rate was observed in the slaughter and processing sector (12%, 95% CI: 0.03-0.17), followed by the retail sector (6%, 95% CI: 0.01-0.13), with the breeding sector showing the lowest rate (5%, 95% CI: 0.03-0.17). Among the regions studied, Shandong exhibited the highest pooled prevalence (15%, 95% CI: 0.01-0.30), followed by Hebei (12%, 95% CI: 0.00-0.30) and Hubei (11%, 95% CI: 0.03-0.09). These findings indicate an uneven distribution of STEC in cattle across China. Our systematic evaluation of data over the past decade provides insights into the prevalence of STEC in cattle in China. These findings may assist in the prevention and control of STEC in cattle in the country. We recommend conducting further epidemiological investigations and establishing comprehensive surveillance programs to identify risk factors associated with STEC in cattle, thereby enhancing prevention and control strategies.</p>","PeriodicalId":12333,"journal":{"name":"Foodborne pathogens and disease","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}