F1000Research最新文献

筛选
英文 中文
Impact of Nutritional and Organoleptic Use of Underutilized Green Leafy Vegetables in Bakery Products: A Systematic Review of Novel Food Applications. 未充分利用的绿叶蔬菜在烘焙产品中的营养和感官利用的影响:对新型食品应用的系统回顾。
F1000Research Pub Date : 2026-08-26 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.180136.2
Madhusudhanan Santhanam, Somu Ga, Senthil Kumaran Piramanayagam, Suresh Sukumar, Nagarajan Theruveethi, Anusha Priyadarsini Kumaresan, Nishar Ahmed Jalaludeen, Rajmohan Dhandapani, Guruprasad Vijayasarathi
{"title":"Impact of Nutritional and Organoleptic Use of Underutilized Green Leafy Vegetables in Bakery Products: A Systematic Review of Novel Food Applications.","authors":"Madhusudhanan Santhanam, Somu Ga, Senthil Kumaran Piramanayagam, Suresh Sukumar, Nagarajan Theruveethi, Anusha Priyadarsini Kumaresan, Nishar Ahmed Jalaludeen, Rajmohan Dhandapani, Guruprasad Vijayasarathi","doi":"10.12688/f1000research.180136.2","DOIUrl":"10.12688/f1000research.180136.2","url":null,"abstract":"<p><strong>Background: </strong>The low utilization of green leafy vegetables (GLVs) makes them a nutrient-dense food that is frequently overlooked in the food system. Their integration into baked products may confer nutritional and organizational benefits. However, few studies have addressed their impact on bakery formulations.</p><p><strong>Objectives: </strong>This systematic review aimed to jointly appraise the nutritional enrichment and sensory properties of bakery products enhanced with the incorporation of underutilized GLVs, and to highlight their potential new food and industrial applications.</p><p><strong>Methods: </strong>Systematic searches were conducted in scientific databases, PubMed, Scopus, Google Scholar, and Web of Science, according to the PRISMA guidelines. Original peer-reviewed research articles reporting nutritional, sensory, functional, technological, or organoleptic outcomes associated with the incorporation of underutilized green leafy vegetables into bakery products. We documented the micronutrient content, bioactive components, consumer acceptability, and technological challenges.</p><p><strong>Results: </strong>One significant difference found in food products was that GLV incorporation increased essential nutrients. Bioactive compounds from GLVs offer health benefits including improved glycemic control and reduced oxidative stress. However, sensory acceptability remains an issue, with bitterness and texture as main obstacles. Consumer studies show acceptable GLV levels depend on species and processing methods. Techniques such as dehydration and fermentation mitigate unwanted sensory effects.</p><p><strong>Conclusions: </strong>As we incorporate more underutilised green leafy vegetables in bakery products, it becomes increasingly evident that they have substantial potential to provide significant nutritional and functional benefits to humans. Future research should address the fine-tuning of formulations to maximize benefits while meeting consumer preferences and ensuring commercial feasibility on a large scale in the food industry.</p><p><strong>Registration: </strong>This systematic review was registered with the Open Science Framework (OSF). DOI: https://doi.org/10.17605/OSF.IO/7YHDZ.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"732"},"PeriodicalIF":0.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148197944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
VIETNAMESE POLITICAL CULTURE: STRUCTURE, ROLE, AND DEVELOPMENT ORIENTATION IN THE NEW ERA. 越南政治文化:新时期的结构、作用与发展方向。
F1000Research Pub Date : 2026-08-25 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.177771.2
Pham Thi Thuy Van, Lai Quoc Khanh
{"title":"VIETNAMESE POLITICAL CULTURE: STRUCTURE, ROLE, AND DEVELOPMENT ORIENTATION IN THE NEW ERA.","authors":"Pham Thi Thuy Van, Lai Quoc Khanh","doi":"10.12688/f1000research.177771.2","DOIUrl":"10.12688/f1000research.177771.2","url":null,"abstract":"<p><p>This article examines the structure and role of Vietnamese political culture in the context of the country's new stage of development, considering the orientations set out in the Draft Political Report submitted to the Fourteenth National Congress of the Communist Party of Vietnam. Applying an interdisciplinary approach that integrates Marxist-Leninist theory, Ho Chi Minh Thought, and contemporary political culture studies, the article conceptualizes political culture not only as a spiritual foundation but also as an internal resource, a soft regulatory mechanism, and a driving force for sustainable development. On this basis, the study proposes a threetier analytical framework of Vietnamese political culture, encompassing values and ideology, norms and political behavior, and institutions and governance culture. Drawing on a synthesis of theoretical perspectives and an analysis of Vietnam's Renovation experience from 1986 to 2025, the article clarifies the dialectical relationship between political culture, institutional quality, governance effectiveness, and social trust. The findings indicate that Vietnamese political culture is undergoing a gradual transformation from a mobilization-oriented model toward a development- and creativity-oriented model, reflecting the interaction between national traditions, socialist ideals, and modern governance principles. The article also outlines policy implications for institutionalizing politicalculture values, strengthening political culture within governance institutions, and supporting Vietnam's development goals through 2030 and the strategic vision for 2045.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"676"},"PeriodicalIF":0.0,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13562953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148955141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving the Uplift Capacity Performance of the Structural Skirt Foundation by Enhancing its Properties. 通过提高裙边基础的性能来提高裙边基础的抗拔性能。
F1000Research Pub Date : 2026-08-24 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.175992.2
Aqeel Jaafar Al-Zubaidi, A'amal A H Al-Saidi
{"title":"Improving the Uplift Capacity Performance of the Structural Skirt Foundation by Enhancing its Properties.","authors":"Aqeel Jaafar Al-Zubaidi, A'amal A H Al-Saidi","doi":"10.12688/f1000research.175992.2","DOIUrl":"https://doi.org/10.12688/f1000research.175992.2","url":null,"abstract":"<p><strong>Background: </strong>Geotechnical engineers are making extensive efforts to improve soil properties and make it suitable and safe for the structures built above it. This research has investigated the use of skirts under shallow footing located on loose sand exposed to uplift loading as a promising method for improving the uplift capacity of soil and a suitable economic alternative to pile foundations.</p><p><strong>Methods: </strong>A loading device, a square footing model, and two groups of skirts (chamfered and straight corners) with different properties (length, inclination angle, roughness, and wings) of the skirt were used. The performance of un-skirted footing situated on loose sand with 30% relative density was analyzed and compared with skirted footing.</p><p><strong>Results: </strong>The results showed that adding (Hy-Rib) metal lath and wings to the skirt significantly improved the uplift capacity. For the footing at L/B = 2 (where L is the skirt length and B is the footing width) and a skirt inclination angle of 0°, the maximum values were 7 and 12 times higher than for the un-skirted footing. When the inclination angle was increased to 45° while maintaining the same embedment ratio of L/B = 2, the uplift capacity significantly increased, reaching values of 27 and 20 times for the straight and chamfered corners with the (Hy-Rib) addition, respectively, and 38 and 27 times for the straight and chamfered corners with the wings added.</p><p><strong>Conclusions: </strong>A significant increase in the uplift capacity of soil was observed by improving its properties by adding a skirt to the shallow footing and making modifications to it using expanded metal lath (Hy-Rib) and wings. The use of skirts has proven to be economically feasible and a successful and promising alternative to the use of uplift piles.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"995"},"PeriodicalIF":0.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13680842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149237468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of General Surgery Education on Dental Students: A Cross-Sectional Study in Iraqi Dental Schools. 普通外科教育对牙科学生的影响:伊拉克牙科学校的横断面研究。
F1000Research Pub Date : 2026-08-24 eCollection Date: 2025-01-01 DOI: 10.12688/f1000research.163454.3
Ali Jabbar Alsheakh, Najih Alaridhy, Saif Anmar Badran, Faaiz Alhamdani
{"title":"The Influence of General Surgery Education on Dental Students: A Cross-Sectional Study in Iraqi Dental Schools.","authors":"Ali Jabbar Alsheakh, Najih Alaridhy, Saif Anmar Badran, Faaiz Alhamdani","doi":"10.12688/f1000research.163454.3","DOIUrl":"10.12688/f1000research.163454.3","url":null,"abstract":"<p><strong>Background: </strong>Different dental schools might adopt different educational approaches in relation to general surgery subject. In Iraqi dental schools' general surgery subject is usually given for the fourth academic year students. To the best of the authors' knowledge, no previous study tried to investigate undergraduate dental students' attitude toward different aspects of this subject.</p><p><strong>Methods: </strong>Google-form questionnaire of three main domains was circulated to fourth- and fifth-year dental students in 3 dental schools. These students are given lectures on general surgery by either a physician or oral surgeon.</p><p><strong>Results: </strong>Two hundred and sixty-five students participated in this study. most responses were positive toward general surgery subject. Chi-Square Test showed a highly significant relationship ( <i>P</i>=0.000) between the relevance of GS to OS and the extent that general surgery helps in understanding oral surgery. The same test showed a significant relationship ( <i>P</i>=0.021) between willingness to become OMF surgeon and the wish to be given GS subject by oral surgeon.</p><p><strong>Conclusion: </strong>General surgery enjoys a reasonable level of popularity among undergraduate senior dental students. This popularity seems to influence the willingness of undergraduate students to become oral and maxillofacial surgeons. This in turn made students prefer general surgery to be given by oral surgeon.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"14 ","pages":"521"},"PeriodicalIF":0.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13560059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148955269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of social marketing practices in promoting digital etiquette: a descriptive and analytical study on a sample of Fallujah University students. 社会营销实践对促进数字礼仪的影响:对费卢杰大学学生样本的描述性和分析性研究。
F1000Research Pub Date : 2026-08-24 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.173990.2
Reham Moatasem Hamza, Ahmed Abbas Hammadi
{"title":"The impact of social marketing practices in promoting digital etiquette: a descriptive and analytical study on a sample of Fallujah University students.","authors":"Reham Moatasem Hamza, Ahmed Abbas Hammadi","doi":"10.12688/f1000research.173990.2","DOIUrl":"https://doi.org/10.12688/f1000research.173990.2","url":null,"abstract":"<p><strong>Background: </strong>The research aims to know the role of social marketing practices in enhancing digital etiquette at the University of Fallujah, through a descriptive and analytical study on a sample of students amounting to (215) students. The research problem was the deficiency in some students' commitment to digital etiquette. The importance of the study is highlighted in analyzing the impact of social marketing tools on raising awareness of ethical values on the Internet and elsewhere. The research recommends the necessity for Iraqi universities to adopt innovative social marketing practices to enhance digital responsibility, and develop technological infrastructure and human resources in line with the modern digital environment.</p><p><strong>Methodology: </strong>The research followed the descriptive analytical approach, and the data were collected via a questionnaire. The data were analyzed using the program (SPSS V.24) based on arithmetic means, standard deviations, the simple correlation coefficient (Pearson), and multiple linear regression testing to verify the influence relationships between the study variables.</p><p><strong>Results: </strong>Analytical results indicate that the university regularly adopts social marketing tools and activates its four dimensions (social product, social pricing, social promotion, and social distribution), which has had a positive impact on digital transformation. The data showed an increase in the level of commitment to digital etiquette among students by (25%) according to the approved digital behavior standards, with a significant moral impact (p < 0.05) of social marketing practices in promoting positive digital behaviors and reducing irresponsible behaviors.</p><p><strong>Conclusions: </strong>Social marketing practices play an important role in raising awareness among Fallujah University students about the importance of responsible digital behavior. The use of various methods such as awareness videos, graphics, and direct interaction with students also helped deliver ethical messages more effectively. The study confirms that social marketing is a real catalyst for social change in the digital environment.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"553"},"PeriodicalIF":0.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13631445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149106447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Dynamics Study of Supramolecular Complexes to the Carbohydrate-Cation System. 碳水化合物-阳离子体系超分子配合物的分子动力学研究。
F1000Research Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.173339.2
Dhaidan Khalaf Kafi, Ali Taher Mohi
{"title":"Molecular Dynamics Study of Supramolecular Complexes to the Carbohydrate-Cation System.","authors":"Dhaidan Khalaf Kafi, Ali Taher Mohi","doi":"10.12688/f1000research.173339.2","DOIUrl":"10.12688/f1000research.173339.2","url":null,"abstract":"<p><strong>Background: </strong>It is known that calcium ions lead to aggregation of disaccharides, while magnesium ions do not. In this study, simulation results indicated that the cations primarily bind to the sulfate groups of the disaccharides.</p><p><strong>Methods: </strong>From molecular dynamics simulations, the differences between the calcium and magnesium cation systems can be explained. Additionally, when a modified water model is used in the case of the magnesium system, in which the charges of the water atoms are reduced, the magnesium ions bind the hydration shell less strongly than in the 'normal' water model, which facilitates complex formation with the disaccharides. To verify whether the stability differences between the two saccharides are also observed in the simulations, the simulations of the calcium system were repeated with the monosaccharide.</p><p><strong>Results: </strong>Moreover, result in the formation of carbohydrate-cation-carbohydrate complexes, with the disaccharides primarily binding to the glucose unit, which is attached to the sulfate group. If the cation is not present, the sulfate groups repel each other and complex formation is not possible. The differences between the two cation systems can be explained as follows: Magnesium ions bind much weaker to the disaccharide than calcium ions. The reason is that magnesium ions bind more strongly to the hydration shell due to their smaller ion radius compared to calcium ions. This is energetically more expensive in the case of magnesium ions, which leads to a kinetic hindrance of complex formation compared to the calcium system. The other significant difference between the two cation complexes is that in the case of calcium ions, both disaccharides bind directly to the cation through the sulfate groups.</p><p><strong>Conclusions: </strong>As expected, the binding energy of the monosaccharide complex was found to be lower than that of the disaccharide complex (6 kJ/mol). The difference in binding energies between the two complexes was relatively small. A significantly lower rupture force was found in the simulations for an individual complex.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"503"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13571022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148967335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the Impact of Disaggregates Government Expenditure on Economic Growth in Iraq. 分类政府支出对伊拉克经济增长的影响分析。
F1000Research Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.177997.2
Abdullah Qasim Mohammed, Muhannad Khamis Abd
{"title":"Analysis of the Impact of Disaggregates Government Expenditure on Economic Growth in Iraq.","authors":"Abdullah Qasim Mohammed, Muhannad Khamis Abd","doi":"10.12688/f1000research.177997.2","DOIUrl":"https://doi.org/10.12688/f1000research.177997.2","url":null,"abstract":"<p><strong>Background: </strong>Iraq heavily depends on oil revenues, which expose it to global oil price fluctuations as well as structural crises. Therefore, in the 2004-2023 crisis period, Iraq experienced economic shocks that followed the change in global prices and internal disturbances that undermined the stability and an enabling environment for growth. The government spending in the last five years has increased; however, its contribution to economic growth has been limited due to poor targeting on productive investment-driven expenditure and high reliance on current spending in the budget.</p><p><strong>Methods: </strong>This study adopts a quantitative methodology using time series data for the period 2004-2023 in Iraq. The Autoregressive Distributed Lag (ARDL) model was used, which is employed to analyse the short- and long-term correlation between economic variables.</p><p><strong>Results: </strong>Finally, the econometric tests findings indicate a long-term cointegration correlation between government spending components, oil prices, and the inflation rate, and economic growth. There was a direct correlation between investment spending, education spending, and oil barrel price and economic growth, and an inverse correlation between current spending, health spending, and the inflation rate and economic growth.</p><p><strong>Conclusions: </strong>While the impact of the current spending factor is of low intensity, investment spending is an active factor in stimulating economic growth in Iraq. Therefore, it is important to reorient the fiscal regime to support investment fields with production tendency and introduction of reform policies that promote economic elasticity and weak dependence on oil money.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"1112"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13560066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148955354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The complete Chloroplast Genome of Dianthus Helenae, an Endemic Species with Medicinal Potential from the Nuratau Mountains, Uzbekistan. 乌兹别克努拉托山具有药用价值的特有种滇石竹的叶绿体全基因组研究。
F1000Research Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.180038.4
Ibrokhimjon Ergashov, Farkhodjon Mingboev, Farruhbek Rasulov, Diyorjon Hamrayev, Davronjon Sultonov, Risolat Achilova, Saidkamol Xaydarov, Bakhrom Khujamkulov, Feruza Utayeva, Oysha Jabborova, Ziyoviddin Yusupov
{"title":"The complete Chloroplast Genome of <i>Dianthus Helenae</i>, an Endemic Species with Medicinal Potential from the Nuratau Mountains, Uzbekistan.","authors":"Ibrokhimjon Ergashov, Farkhodjon Mingboev, Farruhbek Rasulov, Diyorjon Hamrayev, Davronjon Sultonov, Risolat Achilova, Saidkamol Xaydarov, Bakhrom Khujamkulov, Feruza Utayeva, Oysha Jabborova, Ziyoviddin Yusupov","doi":"10.12688/f1000research.180038.4","DOIUrl":"10.12688/f1000research.180038.4","url":null,"abstract":"<p><p><i>Dianthus helenae</i> Vved. is an endemic medicinal species of the Nuratau Mountains, Uzbekistan, and its genomic resources have remained largely unavailable. In this study, we sequenced, assembled, and characterized the complete chloroplast genome of <i>D. helenae</i> and evaluated its phylogenetic position within <i>Dianthus.</i> The plastome exhibited a typical circular quadripartite structure with a total length of 149,567 bp, comprising a large single-copy (LSC) region of 82,856 bp, a small single-copy (SSC) region of 17,105 bp, and a pair of inverted repeats (IRs) of 24,803 bp each. The genome contained the typical set of chloroplast genes, including protein-coding genes, transfer RNAs, and ribosomal RNAs, with duplicated genes located in the IR regions. Phylogenetic analysis based on complete chloroplast genome sequences strongly supported the placement of <i>D. helenae</i> within <i>Dianthus</i> and recovered it as a distinct lineage relative to other sampled species. Sliding window analysis of nucleotide diversity revealed uneven sequence variation across the plastome, with higher variability in the SSC and LSC regions than in the IRs. Several highly variable loci, including <i>trnK-UUU</i> , <i>rps16-trnQ-UUG</i> , <i>rpl32</i>, <i>ycf1</i>, and ndh-associated regions, were identified as potential molecular markers. These results provide an important genomic resource for <i>Dianthus</i> and establish a foundation for future phylogenetic, taxonomic, conservation, and molecular identification studies of this endemic Central Asian species.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"727"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13562929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148955087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Quality Draft Genome Sequence of Endophytic Kluyvera Ascorbata Strain PCL31 Isolated from Piper Crocatum (red betel). 红槟榔内生Kluyvera Ascorbata菌株PCL31的高质量基因组序列草图
F1000Research Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.183746.2
Elizabeth Sidhartha, Rahadian Pratama, Ernst Richard Ng, Irene Nathania Christiawan, Yeshaya Valentine, Rio Hermantara, I Made Artika, Okti Nadia Poetri, Mega Safithri
{"title":"High-Quality Draft Genome Sequence of Endophytic <i>Kluyvera Ascorbata</i> Strain PCL31 Isolated from <i>Piper Crocatum</i> (red betel).","authors":"Elizabeth Sidhartha, Rahadian Pratama, Ernst Richard Ng, Irene Nathania Christiawan, Yeshaya Valentine, Rio Hermantara, I Made Artika, Okti Nadia Poetri, Mega Safithri","doi":"10.12688/f1000research.183746.2","DOIUrl":"https://doi.org/10.12688/f1000research.183746.2","url":null,"abstract":"<p><p>Endophytic bacteria within medicinal plants are a largely untapped reservoir of bioactive compounds and adaptive genetic traits. <i>Piper crocatum</i> (red betel), a Southeast Asian medicinal herb rich in flavonoids, alkaloids, and phenolics, offers a chemically selective niche for endophytes, yet the genomes of its microbial associates remain poorly characterised. <i>Kluyvera ascorbata</i> occurs as a plant-associated endophyte and an opportunistic human pathogen, and its chromosomal <i>bla</i>KLUA gene is the recognised progenitor of the clinically important CTX-M-2 β-lactamase sublineage. We report a high-quality draft genome of endophytic strain PCL31, isolated from surface-sterilised <i>Piper crocatum</i> tissues collected in Bogor, Indonesia. Whole-genome sequencing used the Oxford Nanopore PromethION platform, with <i>de novo</i> assembly in Flye, polishing in Medaka, and quality assessment by QUAST and BUSCO. The assembly spans 4,978,299 bp across eight contigs (N50 1.45 Mbp; GC content 54.26%; 100% BUSCO completeness, <i>enterobacterales_odb10</i>, n = 440). Species identity was confirmed by digital DNA-DNA hybridisation (dDDH 88.6% against the type strain <i>K. ascorbata</i> ATCC 33433) and average nucleotide identity (ANI 98.6% against reference genome NZ_CP096201.1). Annotation identified 4,579 protein-coding sequences, 22 ribosomal RNA, 88 transfer RNA, and 81 non-coding RNA genes, and no CRISPR/Cas systems. antiSMASH 8.0 predicted four biosynthetic gene clusters (BGCs): a 53.8 kb non-ribosomal peptide synthetase (NRPS)-metallophore cluster matching the conserved enterobactin locus (MIBiG similarity 0.83), plus three low-similarity clusters (≤ 0.50) of uncertain novelty - a ribosomally synthesised and post-translationally modified peptide (RiPP)-like cluster, a terpene-precursor cluster, and an azole-containing RiPP. CARD-RGI profiling returned one Perfect hit ( <i>bla</i>CTX-M-2) and 25 Strict hits, the latter dominated by intrinsic <i>Enterobacteriaceae</i> efflux and target-modification genes; phenotypic confirmation was not performed. This genome provides a resource for bioprospecting secondary metabolites from medicinal-plant endophytes and underscores the value of plant-associated isolates for biosafety and antimicrobial-resistance surveillance in opportunistic pathogens.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"1073"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13687735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychosocial Factors Explaining Academic Dropout among Scholarship Students at a Public University in Peru. 心理社会因素解释秘鲁一所公立大学奖学金学生的学业辍学。
F1000Research Pub Date : 2026-08-21 eCollection Date: 2026-01-01 DOI: 10.12688/f1000research.174541.2
Yefferson Llonto-Caicedo, Guido Alarcón-Villanueva, Ofrmar Dionell Jiménez-Garay, Debora Margarita De Jesus Paredes-Olano, Yessica Marilu Acuña-Romero, Isaí Geremias Ruiz-Díaz, Diana Marilú Sánchez-Alamo, Jorge Luis Vargas-Espinoza, Oscar Jovani Zambrano-Infante, Rogger Orlando Morán-Santamaría
{"title":"Psychosocial Factors Explaining Academic Dropout among Scholarship Students at a Public University in Peru.","authors":"Yefferson Llonto-Caicedo, Guido Alarcón-Villanueva, Ofrmar Dionell Jiménez-Garay, Debora Margarita De Jesus Paredes-Olano, Yessica Marilu Acuña-Romero, Isaí Geremias Ruiz-Díaz, Diana Marilú Sánchez-Alamo, Jorge Luis Vargas-Espinoza, Oscar Jovani Zambrano-Infante, Rogger Orlando Morán-Santamaría","doi":"10.12688/f1000research.174541.2","DOIUrl":"10.12688/f1000research.174541.2","url":null,"abstract":"<p><strong>Introduction: </strong>Student dropout in higher education is one of the most concerning issues on the agendas of countries, and it remains a challenge for the higher education system. This is reflected in cases where, despite the benefits and support provided by the state, students decide to give up their scholarships for various reasons. These reasons include economic, social, psychological, organizational, and interaction-related factors, as well as internal and external factors, all of which highlight the inefficiency of the higher education system.</p><p><strong>Objective: </strong>To examine the associations of social and psychological factors with academic and social integration among scholarship students with low academic performance at a Peruvian public university in 2024.</p><p><strong>Methods: </strong>The methodology involves a quantitative approach, with a descriptive-explanatory level and a non-experimental design, as it is framed within the social sciences.</p><p><strong>Results: </strong>The results of the structural equations rely on the confirmatory factor analysis, whose indices yield the following outcomes: χ <sup>2</sup> = CMIN/df = 1.649, GFI = 0.923, AGFI = 0.955, NFI = 0.906, CFI = 0.996, RMSEA = 0.081 and SRMR = 0.100. These values demonstrate adequate indices for the constructs in the estimated model, which is explained by the six factors associated with academic and social integration in the analyzed sample.</p><p><strong>Conclusions: </strong>The social factors that students consider relevant to academic dropout relate to issues such as difficulties in making friends, the institution failing to provide conditions for healthy social interaction, and family environment. Meanwhile, the motivational factors that students consider relevant to academic dropout pertain to issues related to emotional aspects that influence decision-making, the normative aspect in terms of understanding how higher education functions, and psychological health.</p>","PeriodicalId":12260,"journal":{"name":"F1000Research","volume":"15 ","pages":"405"},"PeriodicalIF":0.0,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13562923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书